Review Phenomena in dermatology Article Bhushan Madke, Bhavana Doshi, Sushil Pande1, Uday Khopkar Department of Dermatology, ABSTRACT Seth GS Medical College and KEM Hospital, Parel, Mumbai For a better understanding of various dermatoses, it is imperative for any physician practising - 400 012, 1Department of Dermatology, NKP Salve dermatology to have a good theoretical knowledge of the underlying pathophysiologic Institute of Medical Sciences processes involved in various systemic diseases involving the skin. For an easy grasp over and Lata Mangeshkar this topic, we have discussed the various phenomena under three broad categories, like (a) Hospital, Hingna, Nagpur, India clinical – Meyerson, Meirowsky, pathergy, Renbok, (b) laboratory – LE cell, prozone and (c) histopathology – Splendore-Hoeppli. Address for correspondence: Dr. Uday Khopkar, Department of Dermatology, Key words: Borst Jadassohn, Olfleck’s, Splendore Hoeppli, phenomenon, dermatology Seth GS Medical College and KEM Hospital, Mumbai - 400 012, India. E-mail:
[email protected] “To study the phenomenon of disease without books is Phenomena in dermato-venereology can be divided to sail an uncharted sea, while to study books without into three broad categories, those described in a clinical patients is not to go to sea at all.” setting, in the laboratory or as a histopathological observation [Table 1]. Sir William Osler- British (Canadian born) physician (1849–1919) CLINICAL PHENOMENA INTRODUCTION Koebner/Isomorphic phenomenon In 1877, Heinrich Koebner described the appearance Phenomenon is defined as any sign or objective of psoriatic lesions in the uninvolved skin of symptom; any observable occurrence or fact.[1] In the psoriatic patients as a consequence of trauma.[2] This dermatological literature, the term phenomenon has phenomenon has been dealt in greater detail by several been applied to several peculiar clinical occurrences or laboratory observations.