Hepatitis A Vaccine

Vaccines have saved more lives in Canada in the last 60 years than any other medical intervention. Vaccines help your immune system to recognize and fight bacteria and viruses that cause diseases. Hepatitis A is a vaccine preventable disease. Who can get this vaccine for free? • Hepatitis A (HA) is a virus that infects the liver. For • HA case contacts 6 months and older who are identified every 1,000 people infected, 1 to 3 could die. In adults within 14 days of an exposure. 50 years and older, 18 out of 1,000 cases can die. • Children aged 1-15 years living in northern health • There is no known cure or specific treatment for HA regions or on reserves in Saskatchewan (excluded: infection as it is a self-limiting disease. 25% of adults Creighton, Air Ronge and La Ronge). with HA are hospitalized. • Liver transplant candidates or recipients. • HA is spread through the fecal-oral route: • Haematopoietic stem cell transplant (HSCT) recipients.  By ingesting contaminated food or water (e.g., • Non-immune individuals with bleeding disorders and through food preparation by infected food others who receive repeated infusions of blood or handlers); blood products or plasma-derived replacement clotting  From direct person-to-person contact; or factors.  From contamination of the environment or objects • Individuals who have chronic liver disease (including (e.g., on counter tops and on dishes) as the HA virus alcoholism, hepatitis C, hepatitis B, cirrhosis) who are may remain infectious in the environment for non-immune to HA. several weeks. • Men who have sex with men. • People who eat or drink with or use the same • Individuals that use or share illicit drug snorting, bathrooms as a person who is infectious with HA are at smoking or injection equipment. high risk of becoming infected themselves. • Sexual partners and household contacts of individuals • HA can be spread by sexual contact or through sharing who use illicit drugs. of equipment used for drug use such as straws or pipes. Who should not get this vaccine? What are the symptoms of HA? • A mild illness, with or without fever, is not a reason to • The time between becoming infected and developing avoid immunizations. symptoms is 15 to 50 days. • Persons who have a serious illness, with or without a • Symptoms usually last from 1-2 weeks, but may last for fever, should delay immunization. months and include: • Persons who have had a life-threatening reaction to a  Fatigue, fever, loss of appetite and nausea. previous dose of a HA containing vaccine, or any  Jaundice (yellow colouring of the skin and whites of components of the vaccine. the eyes). • Women who are pregnant or breastfeeding should  Dark-colour urine and light colour stools. inform their nurse or doctor before receiving the • Some infected persons may not develop any symptoms vaccine. but can still spread the HA virus. • Cases are infectious 2 weeks before they start What are common reactions to this vaccine? developing symptoms and for 1 week after developing • Vaccines are very safe. It is much safer to get this jaundice. vaccine than to get HA. • Temporary soreness, redness and swelling at the How can HA be prevented? injection site. • Be immunized. When you / your child get immunized, • Headache, fatigue, fever, and stomach upset may also you help protect others as well. occur after getting the vaccine. • Practice good hygiene (e.g. handwashing). • These reactions are mild and generally last 1 to 2 days.

It is important to stay in the clinic for 15 minutes after getting What does this vaccine contain? any vaccine because there is an extremely rare possibility of a AVAXIM® and AVAXIM® PEDIATRIC contain inactivated life-threatening allergic reaction called anaphylaxis. hepatitis A virus (GBM strain), 2-phenoxyethanol, This may include hives, difficulty breathing, or swelling of the formaldehyde, aluminum hydroxide (expressed as throat, tongue or lips. If aluminum), Medium 199 Hanks in water for injection, this happens after you polysorbate 80, neomycin is present in trace amounts. leave the clinic, call 911 or Thimerosal-free. Latex-free. the local emergency number. This reaction can HAVRIX® 1440 and HAVRIX® 720 contain formaldehyde- be treated, and occurs in inactivated hepatitis A virus aluminum hydroxide, amino less than one in one acids for injection, disodium phosphate, monopotassium million people who get the phosphate, neomycin sulphate, polysorbate 20, vaccine. potassium chloride, sodium chloride and water for injection. May contain traces of bovine serum albumin. Who should you report reactions to? Thimerosal-free. Latex-free. • Report any adverse or unexpected reactions to your local public health nurse, your doctor, or nurse practitioner as VAQTA® contains inactivated hepatitis A virus protein, soon as possible. aluminum hydroxyphosphate sulfate, sodium chloride, Talk to a public health nurse: sodium borate, water for injection, neomycin, bovine • If you have questions or concerns about your or your albumin, and formaldehyde. Thimerosal-free. Latex is child’s reaction to an immunization. present in the vial stopper. • If you had to take your child to a doctor, a hospital or to a health centre with a symptom that might be related to To ensure that a complete immunization record is immunization. maintained, every immunization administered to an individual will be documented by Public Health into the For more information contact your local public health office, electronic provincial immunization registry, known as your physician, nurse practitioner, HealthLine online or by Panorama. Panorama is a secure electronic system used calling 811. in Saskatchewan to record and manage immunization records and the health information related to Mature Minor Consent immunization for all Saskatchewan residents. It is recommended that parents/guardians discuss consent for Immunization records may be shared with other health immunization with their children. Efforts are first made to get care professionals to provide public health services; parental/guardian consent for immunizations. However, assist with diagnosis and treatment; and to control the children at least 13 years of age up to and including 17 years of spread of vaccine preventable diseases. Information age, who are able to understand the benefits and possible about Panorama is detailed in the “Protecting the Privacy reactions for each vaccine and the risks of not getting of Your Immunization Record” fact sheet. immunized, can legally consent to or refuse immunizations in Saskatchewan by providing mature minor informed consent to References: Product monographs (AVAXIM® 2015; a healthcare provider. AVAXIM® PEDIATRIC 2015; HAVRIX® 2016; VAQTA® 2013).

Rev. August 2017