The Holocaust Is a Significant and Independent
ANTICANCER RESEARCH 41 : 2745-2757 (2021) doi:10.21873/anticanres.15056 Review The Holocaust Is a Significant and Independent Risk Factor of Late-Onset Cancers: A Systematic Review of the Literature and Original Data on Jewish Israeli, Jewish Non-Israeli and Non-Jewish Non-Israeli Survivors EDOARDO VIRGILIO 1,2 , DANIELE CAMILLI 3, GIORGIA GILI 4, FILIPPO MONTALI 2,5 , CARLO SALVEMINI 2, ALFREDO ANNICCHIARICO 1, LORENZO PAGLIAI 1, ANDREA MORINI 1, ANDREA ROMBOLI 6 and RENATO COSTI 1,2 1Department of Medicine and Surgery, University of Parma, Parma, Italy; 2Department of General Surgery, di Vaio Hospital, Fidenza, Italy; 3Tusciaweb Journal, Viterbo, Italy; 4Science for the Conservation and Restoration of Cultural Heritage, Pesaro, Italy; 5Department of Experimental Medicine, University of L’Aquila, L’Aquila, Italy; 6Department of General Surgery, Guglielmo da Saliceto Hospital, Piacenza, Italy Abstract. Background/Aim: Seventy-six years after Auschwitz A statistically significant association between the Holocaust and Liberation, the Holocaust keeps on persecuting its surviving development of late-onset cancer in HS was seen in most studies victims. As witnessed by the psychiatric and medical literature with cancer adversely impacting the survival. We also selected in the last decades, in fact, the Holocaust survivors (HS) appear 330 noted Jewish non-Israeli HS: genocide-related late-onset to suffer from several Shoah-related late-onset diseases cancer resulted to be a significant and independent risk factor impacting their survival, such as internal illnesses and post- of poor prognosis (p<0.0001) imparting shorter survival in traumatic stress disorder (PTSD). Cancer represents a further affected versus non-cancer subjects (57 versus 64 years, severe pathology which seems to be connected with the respectively, p=0.0001).
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