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Home , Hemolysin, MAPK1, MAPK3, MAPK4, MAPK6, Oxoeicosanoid receptor 1

Neurotransmitter receptorsGABA and A postsynapticreceptor activation signal transmission

Ligand-gated channel transport

GABAGABA Areceptor alpha-5 alpha-1/beta-1/gamma-2 subunit GABA A receptor alpha-2/beta-2/gamma-2GABA receptor alpha-4 subunit GABAGABA receptor A receptor beta-3 subunitalpha-6/beta-2/gamma-2 GABA-AGABA receptor; A receptor alpha-1/beta-2/gamma-2GABA receptoralpha-3/beta-2/gamma-2 alpha-3 subunit GABA-AGABA receptor; receptor benzodiazepine alpha-6 subunit site GABA-AGABA-A receptor; receptor; GABA-A anion site channel (alpha1/beta2 interface) GABA-A receptor;GABA alpha-6/beta-3/gamma-2 receptor beta-2 subunit GABAGABA receptorGABA-A receptor alpha-2receptor; alpha-1 subunit subunit GABA site

Serotonin 3a (5-HT3a) receptor GABA receptorGABA-C rho-1 subunitreceptor GlycineSerotonin receptor subunit3 (5-HT3) alpha-1 receptor GABA receptor rho-2 subunit GlycineGlycine receptor receptor subunit subunit alpha-2 alpha-3

Ca2+ activated K+ channels

Metabolism of ingested SeMet, Sec, MeSec into H2Se SmallIntermediateSmall conductance conductance conductance -activated calcium-activated calcium-activated potassium potassium potassiumchannel channel channel protein 2 protein 1 4 Small conductance calcium-activatedCalcium-activated potassium potassium channel alpha/beta channel 1 protein 3 Calcium-activated potassiumHistamine channel subunit alpha-1 N-methyltransferase Neuraminidase Pyrimidine biosynthesis

Nicotinamide N-methyltransferase Adenosylhomocysteinase PolymerasePolymeraseHistidine basic proteincatabolism acidic 2 protein Influenza Life Cycle FusionHemagglutinin of the Influenza Virion to the Host Endosome Dihydroorotate dehydrogenase UncoatingBudding of the InfluenzaPA/PB1 Virion Uridine Dihydroorotase5'-monophosphate synthase Packaging of EightRelease RNA Segments

Entry of Influenza Virion into Host Cell via Endocytosis

Viral mRNA Translation Assembly of Viral Components at the Budding Site Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus

Purine salvage Sialic acid metabolism

Transport of organic anions Serotonin (5-HT) receptor D-3-phosphoglycerateSerine biosynthesis dehydrogenase G alpha (s) signalling events Glycosphingolipid metabolism Glucagon-type receptors Potassium transport channels

AMP deaminase 1 Deoxycytidine AdenosineAMP deaminase deaminase 2 Metabolism of and pterines Hypoxanthine-guanineSialidase 3 phosphoribosyltransferaseAdenosine kinase Pyrimidine salvage ATP-sensitive inward rectifier potassium channel 10 Trace amine-associated receptor 1 Sialidase 2 Adenosine deaminase-like protein ATP-sensitive inward rectifier potassium channel 1 CMP-N-acetylneuraminate-beta-1-4-galactoside alpha-2-3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2-3-sialyltransferaseuptakeBeta-galactoside and transport alpha-2-6-sialyltransferase 1 1 Solute carrier organic anion transporter family member N-acylneuraminate-9-phosphatase1C1 Sialidase 4 Solute carrierSolute organic carrier anionorganic transporter anion transporter family family member member 4A11A2 Amine ligand-binding receptors SoluteSolute carrier carrier organic organic anion anion transporter transporter family family member member 2A1 1B1 vRNP Assembly Vasoactive intestinal polypeptide receptor 2 SoluteSolute carrier carrier organic organic anion anion transporter transporter family family member member 1B3 2B1 Vasoactive intestinal polypeptide receptor 1 Urea cycle Formation of the cornified envelopeProton-coupled folate transporter Growth hormone-releasingGastric inhibitoryGastric inhibitory polypeptide polypeptide receptor hormone receptor PituitaryPituitary adenylate adenylate cyclase-activating cyclase-activating polypeptide polypeptidetype I receptor Glucagon-likeSecretin receptor peptide 2 receptor Metabolism of Angiotensinogen to Angiotensins PhosphodiesteraseFollicle stimulatingProstanoid hormone EP4 receptor receptor 3 Kinesins Luteinizing hormone/ChoriogonadotropinAmylin receptorG AMY1- protein-coupled CALCR/RAMP1 receptor kinase 6receptor OrnithineHeme carbamoyltransferase degradation COPI-dependent Golgi-to-ERFolateFolate transporter receptor retrograde 1 beta traffic Adenosine receptors; A2a & A3 AdrenomedullinProstanoid DP receptor PhosphodiesterasereceptorADM2 AM1; CALCRL/RAMP2 7A Arginase-2- mitochondrial PhosphodiesteraseSerotonin 4 (5-HT4) 4D receptor NeutralExtended ceramidase synaptotagmin-1 ThymidineMethylenetetrahydrofolate phosphorylaseSerine hydroxymethyltransferase- dehydrogenase40S cytosolic ribosomal protein SA NGF-independantSurfactant TRKA metabolism activation CalcitoninProstanoidVasopressin IPgene-related receptor V2 receptorADM peptide type 1 receptor CeramideBeta-glucosidase cytosolic kinase Bifunctional methylenetetrahydrofolateUridine-cytidine kinase 2 dehydrogenase/cyclohydrolase-40S ribosomal mitochondrial protein S6 Adenosine A2 receptor CalcitoninPhosphodiesterase receptorRelaxin receptor4A 1 LysosomalNeutral sphingomyelinaseprotectiveSteryl-sulfataseBeta-glucosidase protein Thymidine kinase-Uridine phosphorylase mitochondrial 1 WNT ligand biogenesis and trafficking Adenosine receptors; A1 & A2a Beta-1PhosphodiesterasePhosphodiesterasePhosphodiesterase adrenergicPhosphodiesterase 11A 7B receptor 10A 3B CorticotropinParathyroid releasing hormone factor receptor receptor 1 SialidaseCargo 1 concentration in the ER Adenosine Adenosinereceptor A2a receptorBeta-3Calcitonin--related adrenergicProstanoid EP2 peptide receptorreceptor receptor- CALCRL/RAMP1 Beta-galactosidaseBeta-hexosaminidaseSphingomyelinCeramide glucosyltransferase subunit alpha CorticotropinBeta-adrenergicAdrenergic releasingRelaxin receptor receptor factor receptor beta;receptorPhosphodiesterase 2 ADRB1 kinase 2 & ADRB32 2A EctonucleotideCollagen biosynthesis pyrophosphatase/phosphodiesterase and modifying MHC class family II antigen memberClass presentation 7 B/2 (Secretin family receptors) PhosphodiesteraseHistaminePhosphodiesteraseAmylin 7 receptor H2 AMY3; 1Breceptor CALCR/RAMP3 AdrenomedullinPhosphodiesterasePhosphodiesterase- receptor-PhosphodiesterasePhosphodiesterase AM2; 8A CALCRL/RAMP3PDE1/PDE5 4C 1A ATP-bindingSolute carrier cassette family sub-family 40 member 1G member 2 Adenosine receptors; A2b & A3 DopaminePhosphodiesteraseSerotonin D1 3A receptor 6Dopamine (5-HT6) D5 receptor receptor PhosphodiesteraseSerotoninPhosphodiesterase 7 (5-HT7) 8 receptor 8B Natural resistance-associated protein 2 COPII (Coat Protein 2) Mediated Vesicle Transport G-protein coupled bile acid receptor 1 AdenosineCalcitonin A2bPhosphodiesterase receptorThyroidPhosphodiesterase;Phosphodiesterase gene-related stimulating 4 hormone peptide 4B PDE3 receptor 1 & PDE4 Activation of Matrix MetalloproteinasesUDP-glucuronosyltransferase 1A4 Guanine -binding protein G(s)- subunit alpha UDP-glucuronosyltransferase 1-1 Synthesis of PE adenylate cyclase 1 Protein Wnt-2 Adenylate cyclase type II oxygenase 2 Protein-glutamine gamma-glutamyltransferase K G alpha (i) signalling events Guanine nucleotide-bindingAdenylate protein G(i)- alpha-1 cyclase subunit type IX ProstasinKallikrein 14 Synthesis of PC KallikreinCaspase-14 8 Clathrin heavy chain 1 Class A/1 (-like receptors) GuanineGlucagon-like nucleotide-binding peptide 1protein receptor G(k)- alpha-3 subunit Cyclophilin B KallikreinMatriptase 5 Vacuolar protein sorting-associated protein 35 ProlylPurine 4-hydroxylase nucleoside subunit alpha-1 phosphorylase ProbableTubulin protein-cysteine beta-1 chain N-palmitoyltransferase porcupine Degradation of the extracellularCollagen-binding matrix proteinAMPCathepsin 1 deaminase 3 Z Kinesin-likeKinesin-like protein protein 1KIF23 TubulinCholine beta-3 kinaseKinesin-like alpha chain protein KIF2C Protein Wnt-3a MelanocortinMelanocortin receptor receptor 2 1 Angiotensin-convertingAngiotensin-converting Bone2 enzyme morphogenetic protein 1 40S ribosomal protein S27 Mast cell Carboxypeptidasecarboxypeptidase AB FolateKinesin receptor heavy alphaKinesin-1 chain heavy isoform chain Phosphoethanolamine/ 5A Centromere-associated protein E MelanocortinMelanocortin receptor (M1 receptor and M4) 5 Adenylate cyclase CathepsinAminopeptidase G A Cathepsin K ionotropic- AMPACOPI-mediated 1 Intraflagellaranterograde transport Neurotrophic receptor type 2 Solute carrier organic anionRenin transporter familyCathepsin member L2 4C1 Dipeptidyl peptidaseAmphiregulin I Kinesin-like protein KIF3ACholine/ethanolamineTubulin kinase beta-2 chain Alpha-2cMelanocortinMelanocortin adrenergic receptorreceptor receptor 3 4 Adenylate cyclase typeCarboxypeptidase V B2 isoform A Glutamate receptor ionotropic AMPA Proto-oncogene protein Wnt-3 Alpha-2aAdrenergic alpha-2 receptor Hedgehog 'off' state Kinesin-like proteinNonsense KIF3B Mediated Decay (NMD)Mitotic enhanced Prometaphase by the Exon Junction Complex (EJC) Regulation of ComplementCoagulation cascade factor X/antithrombin III Cerebroside-sulfataseAcidAlpha-galactosidase ceramidase A N-glycanKinesin-likeKinesin-like trimming protein proteinin the KIFC1 ER KIF1B and /CalreticulinTubulin cycle 1B GlucagonIntrinsic Pathway of Fibrin Clot Formation Serum albumin Matrix metalloproteinaseArginase-1 10 Corticotropin-releasing factor-binding protein Melatonin2-oxoglutarate receptor 1A receptor 1 Matrix metalloproteinase 7 Cytidine deaminase Carboxyterminal post-translational modifications of tubulin Pepsin A Leukocyte elastaseMatrix metalloproteinaseMatrix metalloproteinase 13 15 Beta-hexosaminidaseN-acetylgalactosamine-4-sulfataseBeta-N-acetyl-D-hexosaminidase-A/B subunit beta CannabinoidCannabinoidN-arachidonyl CB2 CB1receptor glycine receptor receptor SerotoninOxoeicosanoid 1f (5-HT1f) receptor receptor 1 Transferrin endocytosis and recyclingCathepsinMatrix H metalloproteinase 11 Cathepsin D SerotoninDopamine 5aC-X-C receptors; (5-HT5a) chemokine D2 & receptor D4 receptor type 7 Coagulation factor V C-C chemokineTaste receptor G-proteinreceptor type type 3 2 member activation 31 Coagulation factor IX MatrixCoagulation metalloproteinase factor VIII HDL remodeling 14 Cathepsin L Mannosyl-oligosaccharideEndo-beta-N-acetylglucosaminidase glucosidase Hydroxycarboxylic acid receptorDopamine 2Long-wave-sensitiveDopamine D4 receptors; receptor D3 &1 D4 Coagulation factor X Serotransferrin Gluconeogenesis ADP-ribosylation factorNeutral 5 alpha-glucosidaseAmplification AB of signal from unattached kinetochores via a MAD2 inhibitory signal G-protein coupled receptorC-C 55 chemokineHM74 nicotinicBBSome-mediated acid receptor GPCR type 8cargo-targeting to cilium Heme oxygenase 1 MelatoninSuccinate receptor receptor 1 C-CC-X-CAlpha-2b chemokine chemokine adrenergicreceptor receptor type 3Gamma-carboxylation receptor type 6 of protein precursors G-protein coupled receptorC-X-C 39 chemokineDopamineC-C chemokineMetabotropicRelaxin-3 receptorD3 receptor glutamate receptor 1receptor receptor type 6 5 type 4 Extrinsic Pathway of Fibrin Clot Formation Matrix metalloproteinase 16 Negative regulation of TCF-dependent signaling by WNT ligand antagonists GABA-BAdenosine receptorStromal 1 cell-derivedRemoval A1 factor receptor 1 of aminoterminal propeptides from gamma-carboxylatedIon channel transport Tryptase Cooperation of PDCL (PhLP1) and TRiC/CCT in G-proteinMicrotubule-dependent beta folding trafficking of connexons from Golgi to the plasma membraneResolution of Sister Chromatid Cohesion G-protein coupled receptor 35 PyrimidinergicPurinergicHistamineSerotonin receptor 1eH3 P2Y14 (5-HT1e)receptor receptor receptor P2Y4 Plasma kallikrein TryptaseMatrixTrypsin metalloproteinase I beta-1 8 Gap junction assembly Peptide ligand-bindingG-protein receptors coupled receptor ChemR23 SerotoninSomatostatinRegulator of1 receptors;G-protein receptorG-protein signaling 5-HT1B 3 coupled 12 & receptor 5-HT1D 81 Beta-chymotrypsin Cathepsin S AdenosineTransport of A3 PurinergicGgamma-carboxylated protein-coupled receptorThrombin receptor and P2Y11 receptor coagulation 44 protein factor X precursors Vitaminfrom the K-dependent endoplasmic protein C reticulum to the Golgi apparatusMatrix metalloproteinase-24 metalloproteinase 17 Endothelial homolog Formation ofPost-chaperonin tubulin folding intermediates tubulin folding by pathwayRecruitment CCT/TriC of NuMA to mitotic centrosomes G-protein coupled receptor 183 Regulator of G-proteinDopamineHistamine signaling D2 receptor H4 8 receptorC5a anaphylatoxin chemotactic receptor Vacuolar ATP synthase subunit S1 CholesterylAminopeptidase N ester transfer protein Legumain RNF mutants show enhanced WNT signaling and proliferation Sphingosine 1-phosphate receptorSomatostatin C-X-CEdg-6 chemokineSerotoninPurinergicG receptorprotein-coupled 1d (5-HT1d) receptor type receptor 4 receptor receptor kinase 5 Neprilysin WNT5A-dependentCalpain 1 internalization of FZD2, FZD5 and ROR2Choline acetylase MetabotropicSerotonin glutamateMetabotropic receptor 1a glutamate(5-HT1a) 3 receptor 7receptor Complement C3 Transmembrane protease 6 Cathepsin F Recruitment of mitotic centrosome proteins and complexes Sphingosine 1-phosphateMetabotropic receptor Edg-8C-C chemokine C-Cglutamate chemokinereceptor type receptor 7 receptor C3atype anaphylatoxin 9 2 chemotactic receptor ADAMTS4Kallikrein 7 Cathepsin E AcetylcholinesteraseStAR-related lipid transfer protein 7- mitochondrialSerine/-protein kinaseSerine/threonine-protein SMG1 kinase PLK4 Lysosphingolipid and LPA receptorsSphingosine 1-phosphate receptor Edg-3 G-protein coupled receptor kinase 2 V-type proton ATPase subunit B- brain isoform ADAMTS1 Subtilisin/kexin type 6 SerotoninApelinNeuropeptide ProstanoidreceptorProenkephalinC-X-C 1b SEP3 chemokinereceptor (5-HT1b)receptor receptor B type receptor 6 Regulation of -like Growth Factor (IGF) transportGuanine nucleotide-binding and uptake protein by G(o)- Insulin-like alpha subunit 1GrowthMatrix Factor metalloproteinase-20Matrix Binding metalloproteinase Proteins 12 (IGFBPs) Serine/threonine- NEK2 SphingosineAngiotensin 1-phosphate G-proteinIIMetabotropic type receptor coupled 2 (AT-2) estrogenRelaxin-3 Edg-5 receptorglutamate receptor receptor 1 2 receptor 4 Vacuolar ATP synthase subunit B- kidney isoform Matrix metalloproteinase-19ADAMTS5 Tubulin beta-514-3-3 chain protein gamma DopamineMetabotropic receptors; glutamateD2 & D3 receptor 8 Islet amyloid polypeptide Anchoring of the basal bodySerine/threonine-protein to the plasma kinase membrane NeuropeptideGalanin receptorApelin 1Y receptorGABA-B receptor typeThrombin 2 Antithrombin-IIIPost-translational protein Glucose-6-phosphate translocaseTriosephosphate NeuropeptidesNeuropeptide B/WGalanin receptor RegulatorY receptor receptor type oftype 1 G-protein 5 3 signaling 4 Common Pathway of Fibrin Clot Formation Membrane-bound transcription factorMalate site-1 protease dehydrogenaseFructose-1-6-bisphosphatase cytoplasmic Kininogen-1 Matrix metalloproteinase-25 ChylomicronLDL clearance receptorHepaticPhosphoglycerate lipaseGlyceraldehyde-3-phosphate mutase 1 Rac GTPase-activating dehydrogenase liver protein 1 Serine/threonine-protein kinase TAO1 SomatostatinSomatostatinSomatostatinSomatostatin receptor receptor 5 receptor 1 receptor 4 2 TrypsinTrypsin II Glucose-6-phosphataseCathepsinAlpha B enolase Tubulin--tyrosineLoss of proteins required for interphase microtubule organization from the centrosome Melanin-concentratingKappaNociceptin hormone receptor receptor 1 Complement C1r Matrix metalloproteinase-2 Mitotic checkpoint serine/threonine-protein kinaseDisassembly BUB1Dickkopf-related of the protein destruction 1 complex and recruitment of AXIN to the membrane Muscarinic acetylcholineMelanin-concentrating receptorNeuropeptide hormone M2 Y receptor type 4 Carboxypeptidase N- catalytic subunit Disintegrin and metalloproteinasePresenilin 1 domain-containing protein 8 Kinetochore protein NDC80 homolog Secreted -related protein 1 Synthesis of UDP-N-acetyl-glucosamine Interleukin-8Complement C1s receptor B COPI-independentPrefoldinGlycolysis mediated Golgi-to-ER transfer retrograde of substrate traffic to CCT/TriC Regulation of PLK1 Activity at G2/M Transition Cannabinoid CB1 receptor/orexinMuscarinic receptoracetylcholineNeuropeptide 1 complex receptorGalanin Y receptorM4 receptor 2 type 1 Interleukin-8Complement factor receptor H A Assembly of active LPL andAdenylate LIPC lipasecyclase type complexes 10 WNT mediated activation ofLoss DVL of Nlp fromCaseinAURKA kinasemitotic I Activationdelta/epsilon centrosomes by TPX2 Casein kinase I receptor Edg-4 Complement factor B Coagulation factor XII Alpha-L-fucosidase 2 Detoxification of Reactive Oxygen Species Putative N-acetylglucosamine-6-phosphate deacetylase Opioid Signalling Thrombin and coagulation factorInterleukin-8 VII receptors- CXCR1/CXCR2Coagulation factor XI Insulin-likeSubtilisin/kexin growth factor type binding 9 protein 1 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 LysophosphatidicLysophosphatidic acid receptoracid receptor Edg-7 Edg-2 Opioid receptors; mu/kappa/delta Lysosome Vesicle Biogenesis TCF dependent signaling in response to WNT Melanin-concentrating hormone receptor 2 Coagulation factor III Insulin-like growth factor binding protein 4 Thymidine kinase- cytosolic Angiotensin II receptor P2Y2 Insulin-like growth factor bindingFurin protein 5 Muscarinic acetylcholine receptors Lysophosphatidic acidBradykinin receptor B1 5 receptor Opioid receptors; mu & delta Matrix metalloproteinase-1 MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) Casein kinase I delta Opioid receptors; mu & kappa Protein disulfide-isomeraseMatrix metalloproteinase A6 HLA-DR 3 antigens-associatedMicrosomal invariant triglyceride chain transfer protein large subunit BradykininNeuromedin-U B2 receptor receptor 2 Lysosomal Pro-XInsulin-like carboxypeptidaseGalectin-1 growth factor binding protein 3 Protein disulfide-isomerase Receptor Mediated Mitophagy 14-3-3 protein epsilon Muscarinic acetylcholineG-protein receptors;coupledNeuromedin-U receptorM2 & M3 4receptor 1 Mu opioid receptorLipoxin A4 receptor Vitamin K-dependent gamma-carboxylase VLDL assembly Interconversion of nucleotide di- and Caseintriphosphates kinase I alpha MuscarinicProbable acetylcholine G-protein receptorcoupled receptor 132 Muscarinic acetylcholine receptors; M1 & M2 Chylomicron assembly6-phosphofructo-2-kinase/fructose-2-6-bisphosphatase 2 Frizzled-1 Glycogen synthase kinase-3 beta Uracil nucleotide/cysteinyl Catalase Thioredoxin- mitochondrial CaseinTruncations kinase I epsilon of AMER1 destabilize the destruction complex Calcium sensingEndothelin-converting receptor enzyme 1 Insulin-like Kallikreingrowth factor 1 binding protein 2 6-phosphofructo-2-kinase/fructose-2-6-bisphosphataseRHO GTPasesHexokinase type Activate IV ForminsNucleoside 3 diphosphate kinase 2 AXIN missense mutants destabilize the destruction complex Endothelin-converting enzyme 2 -2-alphaGlutathione S-transferaseThioredoxin Pi NADPHreductase oxidase 5 2 S37 mutants of beta-catenin aren't phosphorylated Prolactin-releasing peptide receptor LeukocyteInsulin-like proteinase growth 3 factor binding protein 6 Cation-dependent mannose-6-phosphate6-phosphofructo-2-kinase/fructose-2-6-bisphosphatase receptor NADPH oxidase 4 1 Insulin receptor recycling Tyrosine-protein kinaseADP-ribosylationHexokinase transmembrane factor 1 ERO1-like type protein I receptor alpha ROR2 Segment polarity protein dishevelled homolog DVL-3 Serine/threonine-protein kinase Aurora-B CCR5/mu opioid receptor complex Plasminogen Calpain 2 Regulation of FZD by ubiquitination Beta-cateninGlycogen synthase phosphorylation kinase-3 cascade CD81 antigen Subtilisin/kexin type 5 HSP90 chaperoneCaseinCasein kinase cycleII beta II alpha/beta for steroid hormone receptors (SHR) APC truncation mutants have impaired AXIN binding GastrinCholecystokinin releasing peptide A receptor receptor Opioid receptors; delta & kappa SegmentPITSLRE polarity serine/threonine-protein protein dishevelledDihydrofolate homolog kinase CDC2L1 DVL-1 reductase Misspliced GSK3beta mutants stabilize beta-catenin NeurotensinGhrelin receptor receptor 1 C-type lectin domain family 4 member C PITSLRE serine/threonine-protein kinase CDC2L2 RibonucleotideGuanylate reductase kinase NeuromedinMetastin B receptor receptorSphingosine 1-phosphate receptor Edg-1 ROS, RNS production in Non-secretoryAcylamino-acid-releasingGlycogen debranching Chitinaseribonuclease enzyme enzyme1 Condensation of PrometaphaseAurora kinase B/Inner centromereS33 mutants protein of beta-catenin aren't phosphorylated Delta opioid receptor Serine/threonine-protein kinaseCasein ULK1 kinase II NucleosideThymidylate diphosphate kinase kinase 1 Orexin and neuropeptides FF and QRFP bind to their respectiveProteinase-activatedUrotensin receptorsNeurotensin II receptor receptorProteinase-activated receptor 2 receptor 1 CD44 antigenCoagulation factor VII IsocitrateEF-handGamma-glutamyl dehydrogenasecalcium-bindingEosinophilMaltase-glucoamylase peroxidase [NADP] domain-containing cytoplasmic proteinDynamin-2 4B Casein kinase II alpha T41 mutants of beta-catenin aren'tAxin-1 phosphorylated ET-A AggregationfMet-Leu-Phe (Plug Formation) receptor 1/2 M1/M2 MAP/microtubule affinity-regulating kinase 4 Ribonucleoside-diphosphate reductase M1 chain Muscarinic acetylcholineEndothelinBombesinThyrotropin-releasing receptor receptor receptor- subtype-3M5 hormone ET-A/ET-B receptor Bone morphogenetic proteinCoagulation 4 factor VII/ factor Beta-1-4-galactosyltransferaseSphingolipid delta(4)-desaturaseAlpha-L-fucosidase 1 I DES1 Separation of Sister ChromatidsS45 mutants of beta-catenin aren't phosphorylated Muscarinic M1/M5 chimericProkineticin proteinreceptor 2 1 Neuronaldegranulation acetylcholineBrainDipeptidyl Prostaglandinglycogen receptor; peptidase phosphorylase E alpha3/beta4 synthase II 2 Casein kinase II alphaSegment (prime) polarity protein dishevelled homolog DVL-2 Muscarinic acetylcholineType-1 receptor angiotensin AdrenergicII M1 receptor receptor alphaPlatelet activating factor receptor Natural resistance-associated macrophage proteinATP-dependent 1 RNA helicaseLysosomalBeta-glucuronidase DDX3X alpha-mannosidase Casein kinase I gamma 2 ProkineticinNeurotensinEndothelin receptor receptorreceptor 1 2 ET-B Neuronal acetylcholineInosine-5'-monophosphate Serine/threonine-proteinreceptors; alpha-3/beta-4- dehydrogenaseSuperoxide kinase alpha-5- 110 dismutase beta-2 Activin receptor type-1C Glycoprotein hormones alpha chain MuscarinicMuscarinic acetylcholine receptor M1 andreceptor M3 M3 Liver glycogen phosphorylaseTrypsin III Activin receptorPeroxiredoxin-1 type-2B Serine/threonine-protein kinase VRK1 G alpha (q) signalling events Malate dehydrogenase- mitochondrial Chymase Nicotinic acetylcholine receptor alpha6/alpha3/beta4 Activin receptor type-2ASignaling by NODAL Polyadenylate-bindingBaculoviralSerine/threonine IAP repeat-containing protein protein 1 PP1-gamma5 catalytic subunit Collagenase Transient Diacylglycerolreceptor1-acylglycerol-3-phosphate potential O-acyltransferase cation channelBeta-mannosidase O-acyltransferase subfamily 1 M member beta 2 Activin receptor type-1B Glucagon-like Peptide-1 (GLP1) regulates insulin secretionEndoplasmin Nicotinic acetylcholineReceptor-type receptorDiamine tyrosine-protein alpha2/beta4 oxidase phosphatase beta Cyclin-dependent kinase 1/cyclin B1 Proteinase activated receptor 4 Apoptotic Inosine-5'-monophosphateprotease-activatingNADH-cytochrome b5 reductasefactor dehydrogenase 1 (IMPDH) Elongation factor 2 Exportin-1 Cyclin-dependent kinase 1/cyclin B Neuropeptide FF receptor 2 LeukotrieneInsulin-like growth factorA4 IIhydrolase receptorMyeloperoxidaseLysosomal alpha-glucosidase Serine/threonine protein phosphatase 2A- 56 kDa regulatory subunit- alpha isoform 2 ATP-citrateInosine-5'-monophosphateNicotinic acetylcholinesynthase dehydrogenase receptor alpha3/beta4/alpha52 C-C type 1 Leukocyte adhesion -1 Nicotinic acetylcholine receptorProstatic alpha3/betaX acidHeparanase phosphatase Beta-glucocerebrosidase Initiation of Nuclear Envelope Reformation PyroglutamylatedNeuropeptide RFamide FF receptor peptide 1 receptor C-C chemokine receptorThrombopoietin type receptor 5 CyclophilinMacrophage AUrokinase-type migrationSolute inhibitorycarrier plasminogenGlutaminyl-peptide family factor 2- facilitated activatorPyridoxal cyclotransferase glucose kinase transporter member 3 DnaJ homolog subfamily A member 1 G2/mitotic-specific cyclin B1 C-C motif chemokine 5 Urokinase plasminogen activator surface receptor Dynamin-1 ProgesteroneMineralocorticoid receptor receptor Cyclin-dependent kinase 1 C-C chemokine receptorThrombopoietin type 2 Apolipoprotein A-I Peptidyl-prolyl cis-trans isomerase FKBP5 Cilium Assembly mRNA Splicing - Major Pathway LysophosphatidicProstanoid FP receptor acid receptor 4 Potassium voltage-gated channel subfamily B member 1 Gene and protein expression by JAK-STAT Scavengingsignaling after by Interleukin-12 Class F Receptors stimulation finger protein GLI2 Vasopressin V1b Immunoregulatoryreceptor interactions between a Lymphoid and a non-LymphoidLymphocyteOxidized cell function-associated low-density lipoprotein antigen receptor 3- 1CD58 Apolipoprotein B-100 Beta-2 adrenergic receptor Elongation factor 1-alpha 1 Basigin interactions Porphobilinogen synthase Leukocyte common antigen Cadherin-2Adrenergic receptor beta; ADRB1 & ADRB2 Axin1/beta-catenin Orexin receptor 1 Platelet factor 4 Annexin A2/S100-A10 AdrenergicGlutathione receptor beta omega 1 Catenin beta-1 and tyrosine catabolism SerotoninOxytocin 2aPyrimidinergic (5-HT2a) receptor receptor receptorP2Y6 Leukocyte adhesion glycoprotein LFA-1 alpha Hypoxia up-regulated protein 1 Uptake and function of diphtheria toxin Neurokinin 1 receptor Annexin A2 ProgrammedCarbonic cell death anhydrase protein I 4 Phenylalanine-4-hydroxylase HistamineLeukotrieneCysteinylFree fatty B4Neurokinin H1 receptorleukotrieneacid receptorreceptor 1 3 receptor receptor 1 Matrix Dissolutionmetalloproteinase of Fibrin 9 Clot NGF processing Interferon gamma RHO GTPases activate IQGAPs SH2 domain-containing protein 1A Complement factor D S-methyl-5-thioadenosineGlutathione S-transferase phosphorylase A2 Translocation of GLUT4 to the plasma membrane Kynurenine--oxoglutarateDihydropteridine transaminase reductase I SerotoninGonadotropin-releasingPutativeLysophosphatidic 2c P2YMetabotropic (5-HT2c)purinoceptor hormoneglutamate acid 10 receptor receptor 6 5 Cholecystokinin B receptor Triggering receptorAntigen-presenting expressed on myeloid glycoprotein cells 1 CD1d Alpha-1-acid glycoprotein 1 Kallikrein 2 Heat shock cognate 71 kDa protein Ezrin Zinc finger protein GLI1 Serine/threonine protein phosphatase 2A- catalytic subunit- alpha isoform 4-hydroxyphenylpyruvate dioxygenase CysteinylSerotoninLeukotrieneMetabotropicNeurokinin leukotriene B42bglutamate receptor (5-HT2b) receptor 2 2 receptor 1 receptor 1 Guanine nucleotide-binding protein G(q) subunit alpha Protein-arginine deiminase type-2 Sonic hedgehog protein Thymidylate synthaseTCF4/beta-catenin Tyrosine aminotransferase Cysteinyl leukotriene receptor 2 Ribosomal protein S6 kinase alpha 4 Transitional endoplasmic reticulum ATPase ELAV-likeHeterogeneous protein 1 nuclear ribonucleoproteins C1/C2 PhospholipaseLeukotrieneVasopressinProstanoid B4 EP1 C-beta-3receptor V1receptor receptor Purinergic receptor P2Y1 CoagulationNitric-oxide factor XIIICytochrome synthase- b-245 heavy brain chain Recycling pathway of L1 Ribonucleoside-diphosphate reductase RR1 Serotonin 2 (5-HT2) receptor Suppressor of fused homolog Ribonucleoside-diphosphateU4/U6 small reductasenuclear ribonucleoprotein M2Polypyrimidine chain Prp4 tract-binding protein 1 Free fatty acidOther receptor 3 semaphorin interactions Cystine/glutamate transporter Serine/threonine-protein kinaseProcessing Aurora-A of Capped Intron-Containing Pre-mRNA VasopressinFree fatty acidV1a receptor receptor 2 Glycophorin-A cAMP-dependent protein kinase alpha-catalytic subunit -associatedIntegrin alpha-4/beta-7 glycoproteinT-cellInterleukin-8 surface antigen CD2 Serine/threonine protein phosphatase 2A- 55 kDa regulatory Caseinsubunit kinase I/MDM2B-Heterogeneous alpha isoform nuclear ribonucleoprotein A1 Cell surface interactionsL-type aminoat the acid transportervascular 1 wall ADAM10 HSP9014-3-3 and protein hnRNPA2/B1 sigma MonocarboxylateIntegrin transporter alpha-4 1 P-selectin glycoproteinSelectin ligand E P-selectin1 CDK1/Cyclin E Monocarboxylate transporterProto-oncogene 4 tyrosine-protein kinase MER Beta-secretase (BACE) Deregulated CDK5 triggers multiple neurodegenerativeGolgi pathways Cisternae Pericentriolar in Alzheimer's Stack Reorganization disease models Splicing factor 3B subunit 3 Integrin alpha2/beta1 Beta-secretase 1 cAMP-dependentForkhead box protein O3 protein kinase (PKA) Splicing factor 3B subunit 2 Integrin alpha-4/beta-1Vitronectin Alpha-synucleinPCP/CE pathway FK506 binding protein 4 Integrin alpha-5/beta-1 IntegrinIntegrin alpha-M/beta-2 alpha-L/beta-2 (LFA-1) Nitric oxide synthase-Arachidonate5-lipoxygenase/FLAP inducible 5-lipoxygenase Serum amyloid P-component Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes P2X purinoceptor 1 Nitric oxide sythases; iNOS & nNOS Heat shock protein HSP105 Degradation of beta-catenin by the destruction complex Heme biosynthesis HeatTyrosine-protein shock protein kinase FRK HSP 90-alpha Heat shock 70 kDa protein 1 AMP-activatedAMPK alpha2/beta2/gamma1 protein kinase- gamma-1 subunit Fibronectin matrix formation Protein-arginine deiminase type-6 ThioredoxinAMPK alpha1/beta1/gamma2 reductase Thrombin signalling through proteinase activated receptors (PARs) Protein-arginineMultidrug deiminase resistance-associated type-3 protein 4 AMPK alpha1/alpha2 CDK1/CyclinCyclin A/B1/B2 A associated events during G2/M transition Mineralocorticoid biosynthesis Integrin alpha1/beta1 complex Protein-arginine deiminase type-1 Prostaglandin EThioredoxin synthase 3 AMP-activatedAMP-activated protein kinase protein (AMPK) kinase-Degradation alpha-1/beta-1/gamma-1 AMPK of GLI2 by the proteasome Coproporphyrinogen-IIIUroporphyrinogen decarboxylase oxidase- mitochondrial Intercellular adhesion molecule (ICAM-1)- Integrin alpha-L/beta-2 Protein-arginine deiminase type-4 HSF1Thioredoxin activationAMPK alpha1/beta1/gamma3 reductase 1 Fibronectin receptor beta Platelet degranulation AMP-activated protein kinase- beta-1 subunit Dual specificity phosphatase Cdc25C CHL1 interactions Transthyretin Amyloid fiber formationHeat shock protein HSP 90-beta AMP-activatedCyclin-dependent proteinAMPK kinase- alpha2/beta1/gamma1 alpha-2 kinase subunit 5 regulatory subunit 1 SUMOylation of DNA replication proteins Androgen biosynthesis Uroporphyrinogen-IIIProtoporphyrinogen oxidase synthase Fibronectin receptor alpha Sodium/potassium-transporting ATPase Sodium/calcium exchanger 1 78 kDa glucose-regulated protein AMPK alpha1/beta2/gamma1 FGFR2 alternative splicing Integrin alpha-V/beta-1 Sulfonylurea receptors;Sulfonylurea receptor K-ATPHeat 2 channelsshock protein HSP90 GLI3The is role processed of GTSE1 to inGLI3R G2/M by progression the proteasome after G2 checkpointRegulation of APC/C activators betweenmRNA Splicing G1/S and - earlyMinor anaphase Pathway Integrin cell surface interactions Vascular cell adhesionIntegrin protein alpha 1 M Troponin- Localization of the PINCH-ILK-PARVIN complexIntegrin alpha-1 to focal adhesions RUNX3 Regulates Immune ResponseFK506-binding Ryanodineand Cell receptor protein Migration 1 1B SulfonylureaPotassium channel- inwardlyreceptor rectifying- 1- subfamily Kir6.2 J- member 11 Tyrosine- and threonine-specific cdc2-inhibitory kinase Myotonin-protein kinase Chromatin modifying enzymesSulfonylurea receptorAlpha-hemolysin 2- Kir6.2 ATP-binding cassette sub-family B member 9 PIWI-interactingCyclin-dependent kinase 13RNAHeat (piRNA) shock-related biogenesis 70 kDa protein 2 Protein phosphataseDNA methylesterase topoisomerase 1 II beta 3-beta-hydroxysteroid3-beta-hydroxysteroid dehydrogenase/delta dehydrogenase/delta 5-->4-isomerase 5-->4-isomeraseSteroid type 5-alpha-reductase I type II 1 Cytosolic A2 Multidrug resistance-associatedSulfonylurea receptor protein 1 5 Menin Intercellular adhesion molecule-1 NACHT- LRR and PYD domains-containing protein 3 DNA topoisomerase I Cytochrome P450 11B2Estradiol 17-beta-dehydrogenase 3 Integrin alpha-3 Integrin alpha-11 ATP-bindingCanalicularMultidrug cassette resistance-associated multispecific sub-family organic protein anion 6 C transporter member 1 11 Cytochrome P450 21 Steroid 5-alpha-reductase 2 Sodium/potassium-transportingIon homeostasis ATPase alpha-1 chain Multidrug resistance-associated protein 1 Estradiol 17-beta-dehydrogenase 12 Elastic fibre formation Myosin light chain kinase- Eukaryotic translation initiation factor 2 subunit 1 Dual specificity phosphatase Cdc25B associated with elastic fibres Rap guanineRap guaninenucleotideSarcoplasmic/endoplasmic nucleotide exchange exchange factor reticulum factor4 calcium3 ATPase 1 CanalicularMultidrug resistance-associated multispecific organicSerine/threonine-protein anionprotein transporter 7 kinase ULK3 2 Glucocorticoid biosynthesisCytochrome P450 17A1 Serine/threonine-protein kinase ILK-1 ATP-binding cassetteP-glycoprotein sub-family B member1 5 Serine/threonine-proteinTP53-regulating kinase kinase PLK3 Laminin interactions Integrin alpha-10 The NLRP3 HedgehogUbiquitin carboxyl-terminal 'on' hydrolasestate 8 Adrenergic receptor alpha-1 Bone morphogenetic protein 2 APC/C:Cdh1 mediatedAMP-activated degradationAxin-2 proteinSerine/threonine-protein of Cdc20 kinase- and alpha-1kinase other 11 APC/C:Cdh1subunit targeted proteins in late mitosis/early G1 Citric acidAlpha-1a cycle (TCA adrenergic cycle) receptor Lysyl oxidase Heat shockABC-family factor protein proteins1 mediated transport Dual-specificityNUAK tyrosine-phosphorylation family SNF1-like kinase regulated 1 kinase 2 CDC45-related protein ThromboxaneECM A2 receptor proteoglycansIntegrin alpha-V/beta-5Muscle- skeletal receptor tyrosineSmooth protein Musclekinase Contraction Potassium-transporting ATPase Calcium-independent cGMP-dependent protein kinase 2 Regulation of TP53 Activity through Phosphorylation Alpha-1d adrenergic receptor Receptor-type tyrosine-protein phosphataseTissue-type S P2X plasminogen purinoceptor activatorADP 7 signalling Tyrosine-proteinthrough P2Y kinase purinoceptor FGR 1 Tankyrase-1 ActivationActivation of of E2F1 ATR targetin response to replicationat G1/S stress Alpha-1b adrenergic receptor Potassium-transporting ATPase alpha chain 2 Nitric-oxideAlpha-crystallin synthase- endothelial B chain DNA polymerase alpha subunit Ectonucleoside triphosphateCytochrome diphosphohydrolase P450 11B1 2 Alpha adrenergic receptor (1a and 1d) Oligosaccharyl transferase 48 kDa subunitProline-rich AKT1 substrate 1 Tankyrase-2 Ectonucleoside triphosphate diphosphohydrolase 1 Adrenergic receptors; alpha-1 A & B HLA class II histocompatibilityHemoglobin antigen DRB3-1 beta chain Tankyrase 1/2 ReplicationCell division protein cycle A 70 7-related kDa DNA-binding protein kinase subunit Phosphate bond Ectonucleosidehydrolysis11-beta-hydroxysteroid by NTPDase triphosphate proteins diphosphohydrolase dehydrogenase 28 Extracellular matrix organizationNeuropilin-1 Apoptosis regulator Bcl-2 Prostate specific antigen 11-beta-hydroxysteroidEctonucleoside triphosphate diphosphohydrolase dehydrogenase 3 1 MonoamineEotaxin oxidase A Activation of PPARGC1A (PGC-1alpha) by phosphorylation Degradation of DVL Cdc20:Phospho-APC/CCDC7/DBF4 (CellCell divisionmediated cycle checkpointcycle 7-related proteindegradation protein RAD1 kinase/Activator of Cyclin of S phase Akinase) Ectonucleoside triphosphate diphosphohydrolase 4 Integrin alpha-2 Fibronectin ArachidonateInterleukin-6 15-lipoxygenase HLA class II histocompatibility antigen DRB1-1Probable global transcription activator SNF2L2 Cyclin-dependent kinase 5 Activation of the pre-replicative complex Integrin alpha-V/beta-6 Ion transport by P-type ATPasesInduced myeloid leukemia cell differentiationRas-relatedBcl-xL/BAK C3 botulinum protein toxin Mcl-1 substrate 3 cAMP-dependent protein kinase- gamma catalytic subunit RegulationProtein polybromo-1 of HSF1-mediated heat shock response Degradation of AXIN Cross-presentationVitronectin receptor alpha of particulate exogenous antigensPulmonary () surfactant-associated protein D Nuclear receptor ROR-gamma Cyclin-dependent kinase 5/CDK5 activator 1 Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3) Serine/threonine-proteinMonoamine kinase oxidase PIM1 HSF1-dependentTetrahydrobiopterin transactivation (BH4) synthesis, recycling, salvage and regulation Cystinyl aminopeptidase Serine-proteinp53-Dependent kinase ATR G1 DNA Damage Response Platelet Adhesion to exposed collagen Cyclooxygenase-2Cofilin-1 ApoptosisHomeobox protein regulator NANOG Bcl-X Hedgehog ligand biogenesis Topoisomerase (DNA) II binding protein 1 C-C motif chemokine 2 cAMP-dependent protein kinase beta-1 catalytic subunit Degradation of GLI1 by theAsymmetric proteasome localization of PCP proteins MET interacts with TNS proteins PhospholipaseImmunoglobulin D1 epsilon Fc receptor Rap1 signalling Serine/threonine-protein kinase Chk2 Transcription initiation factor TFIID subunit 1-like G2 Phase Beta--1 Beta amyloid A4 protein Ornithine decarboxylase Cyclooxygenase Acyl-protein 1 Proliferating cell nuclear antigenCyclin A2 N(G)-N(G)-dimethylarginine dimethylaminohydrolase 1 Attenuation phase Transcription initiation factor TFIID subunit 1 P2X purinoceptor 3 Caspase-3 AUF1 (hnRNPQuinone D0) reductasebinds 1)and destabilizes mRNA CDK2/Cyclin A1 ShortShort transient transient receptor receptor potential potential channel channel 6 3 Bcl-2-like protein 11 ArylRUNX1 hydrocarbon interacts withreceptor co-factors signalling whoseHh precisemutants effect that on don't RUNX1 undergo targets autocatalytic is not known processing are degraded by ERAD P2X purinoceptor 2 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes Elevation of cytosolic Ca2+ levels Signal transduction by L1 GemininFBXL7 down-regulates AURKA during mitotic entry and in early mitosis MET activates PTK2 signalingP2X purinoceptor 6 CD22 Ribosomal protein S6 kinase alpha 6 Dual specificity phosphatase Cdc25A Cyclin-dependent kinase 2/cyclin A P2XP2X purinoceptor purinoceptor 5Inositol 1-4-5-trisphosphate 4 receptor type 3 Ubiquitin-like modifier-activating enzyme ATG7 eNOS activation Regulation of ornithine decarboxylase (ODC) Cyclin-dependent kinase 2 Inositol 1-4-5-trisphosphate receptor type 1 Phosphoenolpyruvate carboxykinase cytosolic Defective CFTR causes cystic fibrosis DNA-directed RNA polymerase II subunit RPB1 Inositol 1-4-5-trisphosphate receptor Actin-related protein 2 Sema3A PAK dependent repulsion Ubiquitin Mediated Degradation of PhosphorylatedDNA topoisomerase Cdc25A II vonIntegrin Willebrand alpha-V/beta-3 factor Interleukin-10 signaling CaMCaM kinase kinase II delta II beta Werner syndrome ATP-dependent helicase Tumor suppressorOrc1DNA p53-binding removal topoisomerase protein 1from chromatin II alpha CDK2/Cyclin A Integrin alpha-V/beta-3 and alpha-IIb/beta 3 CaM kinase Interleukin-4II and 13 signaling Platelet sensitization by LDL Serine/threonine-proteinAutodegradation kinase Sgk1 of Cdh1 by Cdh1:APC/CNAD-dependent protein deacetylase sirtuin-6 Cyclin-dependent kinase 2/cyclin E1 CaM kinase II alpha Forkhead box protein O1 Regulation of POUPTEN domain- stability class 2- transcription and factor CDT1activity 1 association with the CDC6:ORC:originSerine/threonine-protein complex kinase Chk1 Double-strand break repair protein MRE11A Processing of DNA double-strand break ends Integrin alpha-2/beta-3 CaM kinase II gamma Plasminogen activator inhibitor-1 C-type lectin domain family 4 member K Succinate dehydrogenase [ubiquinone] flavoprotein subunit- mitochondrial VEGF ligand-receptor interactions Protein-tyrosine phosphatase MEG1 MacrophageCystic mannose fibrosis receptor 1 transmembrane conductance regulatorAPC/C:Cdc20 mediated degradation of Securin CalciumRas-related release-activatedORAI protein calcium 1/2/3 Rap-1A channel protein 1 Carbonic anhydraseMitogen-activated protein kinase 6 26S proteasome non-ATPase regulatoryCDK-mediated subunit 14 phosphorylation and removalCyclin-dependent of Cdc6 kinase 2/cyclin E Heat shock protein beta-1 Dual specificity protein phosphataseGlucocorticoid CDC14A receptor Vif-mediated degradation of APOBEC3G Bloom syndrome protein Syndecan interactionsVascularFibrinogen endothelial beta chain growth factor receptor 2Paxillin Low affinity immunoglobulin gamma Fc region receptor II-a CDK-interacting protein 1 Vascular endothelial growth factor receptor Actin- cytoplasmic 1 LipoproteinMitogen-activated lipase protein kinase 4 Meiotic synapsis RNA Polymerase II Pre-transcription Events p130Cas linkage to MAPK signaling for integrins Vascular endothelial growth factor A ProteasomeSCF-beta-TrCP component mediated C5 degradationSerine/threonine-protein of Emi1 kinase Nerve growth factor receptorPlacenta Trk-A growthIntegrin alpha-IIb factor Cross-presentationMenin/Histone-lysine N-methyltransferase of soluble MLL exogenous antigens (endosomes)Transcription of E2F targets under negative controlBreast by p107cancer type (RBL1)SUMO 1 susceptibility E1/E2 and p130protein (RBL2)PausingPausing in complex and and recovery recovery with HDAC1of of HIV Tat-mediated elongation HIV elongation Vascular endothelial growth factor receptor 3 SH2 domain-containing protein 2A Proteasome Macropain subunit MB1 Integrin alpha-IIb/beta-3 Cell division control protein 42 homolog MAPK6/MAPK4 signaling HIV elongation arrest and recovery Vascular endothelial growth factor receptor 1 Rho-relatedHigh GTP-binding affinity immunoglobulin protein RhoB gamma Fc receptor I Serine-proteinTranscription kinase ATM initiation factorSUMO-conjugating IIA G1/S-specificalpha and cyclinbTranscription enzyme E1 UBC9 initiation factor IIA alpha and beta chains EphrinEphrin type-A type-A receptor receptor 1 8 Myosin-9Tyrosine-proteinProtein tyrosine kinase kinase receptor 2 beta UFO Regulation of activated PAK-2p34 by proteasome mediated degradation Human immunodeficiency virus type 1 Tat protein GRB2:SOS provides linkage to MAPK signaling for IntegrinsEphrin type-AEphrin type-A receptor receptor 4 6 Transforming growth factor beta-1 Proteasome subunit beta type-7 CDK3/Cyclin E Ephrin type-A receptor 5 Transforming protein RhoA Toll Like Receptor 4 (TLR4) Cascade Small ubiquitin-related modifier 2 Tat-mediated HIV elongation arrest and recovery Ephrin type-A receptor 7 Rho GDP-dissociation inhibitor 1 Galectin-3 Small ubiquitin-related modifier 1 Cyclin-dependent kinase 9 VEGF binds to VEGFR leading to receptor dimerizationEphrin type-A receptor 2 LIM domainRho-GTPase-activating kinase 1 protein 3 Ribosomal protein S6 kinase alpha 2 TP53 Regulates Transcription of Genes InvolvedCDK3/cyclin in G1 E Arrest Ephrin type-A receptor 3 Androgen Receptor 26S proteosomeProteasome subunit beta type-9 Formation of HIV-1 elongation complex containing HIV-1 Tat Rho-associated protein kinase 1 Serine/threonine-proteinRibosomal kinase protein PAK S6 2kinase alpha 3 CDO in myogenesis Proteasome subunitDual-specificityRegulation beta type-10 tyrosine-phosphorylation of TP53 DegradationFanconi anemia regulated group kinase D2 protein 1A Von Hippel-LindauFormation disease oftumor RNA suppressor/Elongin Pol II elongation B/Elongin C complex EPHA-mediated growthIntegrin cone collapse alphaIIb beta3 signaling Ras-related C3 botulinum toxin substrate 1/T-lymphoma invasion and metastasis-inducing protein 1 Hypoxia-inducible factor prolyl hydroxylase 1 Rho-associated protein kinaseInsulin receptorRas-related C3 botulinum toxin substrate 2 Ribosomal protein S6 kinase alpha 1 Gamma-secretase Egl nine homolog 1 Cyclin A:Cdk2-associated events at S phase entry CDK9/Cyclin K ARMS-mediated activation Bromodomain and WD repeat-containing protein 1 SCF(Skp2)-mediatedDNA degradationDamage/Telomere of p27/p21 Stress Induced SenescenceInteractions of Tat with host cellular proteins Threonyl-tRNA synthetase DNA repair protein RAD51 homolog 1 POU domain- class 2- transcription factor 2 NADH-ubiquinone MLRQ subunit Discoidin domain-containing receptor 2 phospho-PLA2 pathway ETS domain protein Elk-1 Transcription activator BRG1 Mothers against decapentaplegic homolog 2 Formation of HIV elongation complex in the absence of HIVValyl-tRNA Tat synthetase 2 Lysyl-tRNAMethionyl-tRNA synthetase synthetase Cytochrome c oxidase subunit 1 EpithelialRho-associated discoidin domain-containing protein kinase receptor 2 1 Ras-related C3 botulinum toxin substrate 1 Vpu mediated degradation of CD4 Histidyl-tRNA synthetase Dual specificitySignaling -activated by PDGF protein kinase kinase 1 Egl nine Mothershomolog against 3 decapentaplegic homolog 3 CDK9/cyclin T1 Leucyl-tRNA synthetase Ubiquinol-cytochromeCytochrome C reductase c oxidase complex subunit 7.2 kDa2 protein Platelet-derived growth factor subunit A EphrinLIM domain type-B kinase receptor 2 6 CREB phosphorylation through the activation of Ras RNA polymerase II subunit A C-terminal domain phosphatase SSU72 Signaling by high-kinase activity BRAF mutants Ephrin type-B receptor 2 MAP kinase-activated protein kinase 5 CDK2/CDK4 Tat-mediated elongation of the HIV-1 transcriptTyrosyl-tRNA synthetase Cytosolic tRNA aminoacylation Cytochrome b-c1 complex subunit 7 Ubiquitin carboxyl-terminal hydrolase 13 Puromycin-sensitive aminopeptidaseProteasome subunit beta type-8 G0 and Early G1 Arginyl-tRNA synthetase Respiratory electronHeat transportshock protein 75 kDa- mitochondrial Ephrin type-B receptor 1 Ribosomal protein S6 kinase alpha 5 Serine/threonine-protein kinase PAK 3 ProteasomeLRR FLII-interacting Macropain protein 1 subunit (LRRFIP1)Protection activates type of Itelomeres IFN production protein 1 Glutaminyl-tRNA synthetase MAP2K and MAPK activation EphrinEphrin type-B type-B receptor receptor 4 VEGFA-VEGFR2 3 PathwayRegulation ofGastrin-CREB actin dynamics signalling for phagocytic pathway via cupPKC formation and MAPK Ubiquitin-like modifier-activating enzyme 1 RNACDK7/Cyclin Polymerase H/MNAT1 II TranscriptionCyclin Elongation T1 Aminoacyl-tRNAIsoleucyl-tRNASeMet synthetase incorporation into proteins Dual specificity mitogen-activatedProtein-tyrosineMitogen-activated protein phosphatase kinase protein G1 kinase kinase kinase 2 kinase 11 Acylglycerol kinase- mitochondrial Probable ubiquitin carboxyl-terminalTripeptidyl-peptidase hydrolase FAF-X 2 Homeodomain-interactingDeactivation of protein the kinase beta-catenin 2 transactivating complex RNA polymerase II transcribes snRNA genes NADH-ubiquinone oxidoreductaseComplex I biogenesis chain 4 MET activates RAP1 andPrelamin-A/C RAC1Rho GTPase cycle RegulationUbiquitin-like of modifier-activating RUNX3 enzymeexpression 6 and activity DNA repair protein RAD52 homolog Meiotic recombination Non-integrin membrane-ECM interactionsDual specificity mitogen-activated protein kinase kinase; MEK1/2 Atrial natriuretic factor Tyrosine-protein kinase CSK Tyrosine-protein kinase FES Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor TP53Alpha Regulates TranscriptionCyclin-dependent of DNA Repair kinase Genes 7 G alpha (12/13) signalling events Serine/threonine-proteinSerine/threonine-protein kinase kinaseA-Raf c-TAK1 Solute carrier family 2- facilitated glucose transporter memberRhombotin-2 4 Histone acetyltransferase KAT5 Paradoxical activation of RAF signalingSerine/threonine-protein by kinase kinase inactive RAF and BRAFDual specificity mitogen-activated protein kinase kinase 1 (Raf/MEK)Serine/threonine-proteinSerine/threonine-proteinHLA class phosphatase I histocompatibility kinase 5Dual PAK antigen specificity 1 A-3 protein phosphatase 3 Regulation of RAS by GAPs Retinoblastoma-associatedCyclinPTK6 protein E Regulates associated Cell events Cycle during G1/S transition Tyrosine-protein phosphatase non-receptor type 18 ERK/MAPK targets UbiquitinNEDD8-activating carboxyl-terminal hydrolase enzyme 7 E1 regulatory subunit Tyrosine-protein kinase CTK MAPK3 (ERK1) activation Far upstream element-binding protein 2 Ubiquitin carboxyl-terminal hydrolase L5 COP9 signalosome complex subunit 7b Peripheral plasma CASK IL6Ralpha/GP130 Ubiquitin carboxyl-terminal hydrolase isozyme L1 Autodegradation of the E3 ubiquitin ligase COP1 SUMOylation of DNA damage responseCyclin-dependent and repair proteinskinase 7/ cyclin H Frs2-mediated activation RSK activation UCH proteinases Telomerase reverse transcriptase Signaling by moderate kinase activity BRAF mutantsSerine/threonine--raf Tyrosine-protein kinase TYK2 Poly(A)-specific PARN Ubiquitin carboxyl-terminalTGF-beta receptor hydrolase type II BAP1 VonSPRY domain-containing Hippel-Lindau SOCS box proteinTyrosine-proteindisease 2 tumor kinaseLymphoid BRK suppressor enhancer-binding factor 1 PECAM1 interactions EPHB-mediated forward signalingSerine/threonine-protein kinase RAF Interleukin-6 receptor subunit beta MAP kinase p38 alpha Antigen processing: Ubiquitination & Proteasome degradation Tyrosine-protein kinase Srms VEGFR2 mediated vascular permeability Fatty acid binding protein epidermal Sentrin-specific protease 8 Histone deacetylase 6 Signaling by RAS mutants Tyrosine-protein kinase ABL AKT/p21CIP1 Sphingosine kinase 1 ProteinNegative kinase C epsilonfeedback regulation of MAPK pathway Inositol-tetrakisphosphate 1-kinase Ubiquitin carboxyl-terminalRUNX1 regulates hydrolase transcription isozyme of L3 genes involved in differentiation of HSCs Focal adhesion kinase 1/vascular endothelialSignaling growth factorTyrosine-protein receptor by BRAF 3 kinase and BLK RAF fusions Transcription factor MafK Glutamate (NMDA) receptor subunit zeta 1 Signal transducerProtein-tyrosine and activator phosphatase RASof transcription guanyl-releasing 1B 6 protein 1 MAP kinase-interacting serine/threonine-protein kinase MNK1 MAP kinase p38 Packaging Of Telomere Ends Focal adhesion kinase 1 FCGR activation Dual specificity protein phosphatase 10 G2/M CheckpointsNeddylation Transcription factor E2F1 Negative regulationRHODual of GTPases MAPK specificity Activatepathway proteinWASPs and phosphatase WAVEsTyrosine-proteinERKs 2 kinaseare inactivated SRC Factors involved in megakaryocyte development and platelet production Glutamate NMDA receptor; GRIN1/GRIN2BPhospholipase D2 Dual specificityDual protein specificity phosphatase protein 1 phosphatase 4 Glutamate [NMDA] receptor E3 ubiquitin-proteinBromodomain ligase NEDD4 and PHD finger-containing protein 3 TGF-beta receptor type I Kelch-like ECH-associated proteinHomeodomain-interacting 1 protein kinase 1 Poly [ADP-ribose] polymerase-1 RAF activation Dual specificity protein phosphatase 6 Keap1/Nrf2 Formation of the beta-catenin:TCF transactivating complex Src homologyIonotropicGlutamate [NMDA]2 glutamate domain receptor subunitreceptor containing epsilon NMDA 2 transforming1/2C protein C2 KSRP (KHSRP) binds and destabilizes mRNA p53-binding proteinUbiquitin-dependent Mdm-2 degradation of CyclinRepressionSMAD2/SMAD3:SMAD4 D1 of WNT target genes heterotrimer regulates transcription Glutamate NMDA receptor; GRIN1/GRIN2A Core-binding factor subunit beta Protein Mdm4 Bromodomain adjacent to zinc finger domain protein 2A DNATranscription (cytosine-5)-methyltransferase of E2F 3B targets under negative control by DREAM complex Downregulation of ERBB2 signaling Runt-related transcription factor 1/Core-bindingVoltage-dependentPrenyl factor protein subunit specificanion-selective betaprotease channel protein 2 DNA (cytosine-5)-methyltransferase 1 Mitogen-activated proteinCD209 kinaseMAP antigen 7 kinase p38 gamma Insulin-degradingUbiquitin carboxyl-terminal hydrolase enzyme 14 GlutamateGlutamate [NMDA] [NMDA] receptor receptor subunit subunit epsilon epsilon 4 1 delta Ubiquitin carboxyl-terminal hydrolase 47 Endothelial PAS domain-containing protein 1 Glutamate [NMDA] receptor subunit epsilon 3 Spry regulation of FGF signaling DNA polymerase beta NEDD8-activating enzyme E1 catalytic subunit RAS guanyl releasing protein 3 p38 delta/gammaSerine/threonine-protein kinase AKT UbiquitinUbiquitinSenescence-Associated carboxyl-terminal carboxyl-terminal hydrolase hydrolase 10 5 Secretory Phenotype (SASP) Ras-specificDisks guanineSignaling large nucleotide-releasinghomolog by 4 ERBB2 factor 1 MAP kinase ERK2 Advanced glycosylation endproduct receptor signaling Protein-arginine N-methyltransferase 1 proto-oncogene protein Hsp90Hepatocyte co-chaperone growth factor Cdc37 Ub-specific processing proteases E3Association ubiquitin-protein ligase of TriC/CCTTRIM33 DNA-directed with target RNA polymeraseproteins I subunit during RPA1 biosynthesis Tyrosine-protein kinase YES RAF-independent MAPK1/3 activation DSCAM interactions Protein arginine N-methyltransferase 6 Apoptosis regulator BAX ChromoboxProtein protein phosphatase homolog 8 2C alpha Tyrosine-protein kinase HCK Tyrosine-protein kinase FER NIK-->noncanonical NF-kB signaling E3 SUMO-protein ligase CBX4c-Myc/Max Receptor-type tyrosine-proteinSignal attenuation phosphatase alpha Histone-lysine N-methyltransferase NSD2 Mitogen-activatedBeta-nerve growth proteinfactor kinase; ERK1/ERK2 T-cell surface antigen CD4 G1/S-specific cyclin D1 NAD-dependent deacetylaseTumour suppressorsirtuin 1 p53/oncoprotein Mdm2 Signalling to RAS Protein-tyrosine phosphatase 1C Interleukin-12 family signaling CTLA4 inhibitory signaling MAP kinase p38 betaPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1Aryl hydrocarbon receptor Antigen activates B Cell Receptor (BCR) leadingHepatocyte to generation growth factor receptor of second messengers MAPRNA kinase-activated Polymerase protein I Promoter kinaseUbiquitin-like 2 OpeningSerine/threonine-protein modifier-activating enzyme kinase 7 AKT2 Cyclin D associated events in G1 RuvB-like 1 Cellular tumor antigen p53 SUMOylation of chromatin organization proteins MAPK1 (ERK2) activation Bcr/Abl Serine/threonine protein phosphatase PP1-alpha catalytic subunit Interferon-alpha/beta receptor alpha chain DNA-binding protein inhibitor ID-1 GP1b-IX-V activation signallingRole of in RNase L UDP-N-acetylglucosamine--peptideBromodomain-containing N-acetylglucosaminyltransferase protein 7 110 kDa subunit Histone deacetylaseNoRC (HDAC1 negatively and regulates HDAC2) rRNA expression MER intracellular domain/EGFR extracellular domain chimera Protein kinaseTyrosine-protein C alpha kinase Lyn CD209 (DC-SIGN) signaling Tumour suppressor protein p53/Mdm4 Tyrosine-protein kinase receptor RET Mammalian target of Rapamycin (mTORC1) Histone deacetylase complex subunit SAP130 EZH1/SUZ12/EED/AEBP2/RBBP4 complex Bromodomain-containingProtein protein kinase 2 N1 Platelet-derived growth factor subunit B Caspase-1 Dectin-1 mediated noncanonical NF-kB signaling Toll Like Receptor TLR1:TLR2 Cascade Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 Cyclin-dependent kinase 4 NCAM signaling for neurite out-growth Interleukin-1 beta Serine/threonine-protein kinase mTOR CDK4/Cyclin D3 JAK2/TYK2 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet functionCyclin-dependent kinase 4/cyclin D EZH2/SUZ12/EED/RBBP7/RBBP4Histone deacetylase 1 Tyrosine-protein kinase FYN MAP kinaseSignal transducerERK1 and activator of transcription 3 Ubl carboxyl-terminal hydrolase 18 Hypoxia inducible factors; HIF-1-alpha- HIF-2-alpha Histone H4 Mitogen-activatedTRAF2- and protein NCK-interacting kinase kinase kinase kinase kinase 4 CDK6/cyclin D1 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants JAK3/JAK1 Aryl hydrocarbonG1/S-specific receptor cyclin D3 nuclear translocatorTP53 Regulates Transcription of Genes Involved in Cytochrome C Release RNA Polymerase I Transcription Initiation receptor MAP kinase p38 delta Mitogen-activated protein kinaseCarbonic kinase anhydrase kinase IX5 Hypoxia-inducible factor 1 alpha Downregulation of SMAD2/3:SMAD4 transcriptional activity GTPaseTyrosine-protein NRas kinase TIE-2 Breakpoint cluster regionTyrosine-protein protein kinase TEC Regulation of TLR by endogenousp38MAPK events ligand Misshapen-like kinase 1 PI3K/AKT activation Transcription intermediary factor 1-alpha Cyclin-dependent kinase 4/cyclin D1 JAK1/TYK2 Protein kinase C zeta c-Jun N-terminal kinase C-type1 Cyclic lectin AMP-responsive domain family 7element-binding member A protein 1 CDK6/cyclin D2 Transcription factor GATA-4 Constitutive Signaling by EGFRvIII Tyrosine-protein kinase JAK2Linker for activation of T-cells family member 1 Dual specificity mitogen-activated protein kinaseProtein kinase kinase 7 C beta Proto-oncogene c-JUN Peregrin ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression MAP kinase-activated protein kinase 3Serine/threonine-protein kinase AKT3 TNFR2 non-canonical NF-kB pathwayHistoneBromodomain-containing acetyltransferaseRuvB-like 2 KAT8 protein 1 GAB1 signalosome Tyrosine-protein kinase JAK1 Platelet glycoproteinc-Jun 4Dual N-terminal specificity mitogen-activated kinase- JNK protein kinase kinase 4 Cyclin-dependentHistone-lysine N-methyltransferase kinase 6 Oncogene MLL Induced SenescenceHistone-lysine N-methyltransferase- H3 lysine-9 specific 3 Epidermal growth factor receptorRAF/MAP and ErbB2 (HER1kinase and cascadeHER2) Tyrosine-protein kinase JAK3 Interferon alpha/beta signaling c-Jun N-terminal kinase 2 Nicotinamide phosphoribosyltransferase Histone deacetylaseHistone 4 deacetylaseHistone deacetylase7 Protein phosphatase 2C beta JNK2/JNK3 Early growth response protein 1 Bromodomain-containing protein 8 Tyrosine-protein kinase SYK Eukaryotic translationActivation initation factor of the AP-1 family of transcription factors RUNX3 regulates p14-ARFCDK6/cyclin D3 Histone deacetylaseTranscription 11 factor Sp1 MET activates PI3K/AKT signaling JAK2/JAK1 -gamma-2 Eukaryotic Importininitiation subunit factor alpha-2 4A-I Serine/threonine-protein kinase SIK1 Transforming protein p21/H-Ras-1 c-Jun N-terminal kinase 3 Fibroblast growth factor receptor 3 Signaling by SCF-KIT Interferon-induced- double-stranded RNA-activated protein kinase Regulation of by Hypoxia-inducible FactorRegulation of TP53 ActivityHistone through deacetylaseAcetylation 9 Son of sevenless homolog 1 GTPase KRas Lysine-specific demethylase 7 JAK1/JAK2/TYK2 Mitogen-activated protein kinase kinase kinase 8 Regulation of RUNX1 Expression and Activity Neurogenic notch homolog protein 2 Fibroblast growth factor receptor 2 Tumor factor receptor superfamily memberLysine-specific 10B demethylaseRUNX1 7A/7B regulates transcription of genes involved in differentiation of myeloidHistone-lysine cells N-methyltransferase- H3 lysine-9 specific 5 Neurogenic locus notch homolog protein 4 Histone deacetylase 10 Epidermal growth factor receptor erbB1 Proto-oncogene vavSignal transducer and activator of transcription 1-alpha/beta Neurogenic locus notch homolog proteinCircadian 3 Clock Histone deacetylase 1/3/5/8 ProlactinPKC alpha andreceptor beta-2 TRAIL receptor-1 Mitogen-activated protein kinase kinase kinase 3 Oxidative Stress InducedGTP-binding Senescence protein Rheb Histone deacetylase 8 Nephrin family interactions TNF-alpha Histone deacetylase 2 RET signaling Phosphatidylinositol 3-4-5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN PI3K events in ERBB2 signaling Fibroblast growth factor receptor 1 Dual specificity mitogen-activatedER- protein kinase kinaseLysine-specific pathway 3 histone demethylase 1B Histone deacetylase 5 SHC-transforming protein 1 Interleukin-2 receptor alpha chain FCERI mediatedProtein MAPK kinase activation C- PKC; classical/novelTumor necrosis factor receptor R1 Nuclear receptor coactivator 3 Pantothenate kinase 1 Peptide N-myristoyltransferase Nuclear receptor ROR-alpha Pantothenate kinase 3 aminopeptidasePhosphodiesterase 2 6 WD repeat-containing protein 5 PI3-kinase p85-alpha subunit Receptor protein-tyrosine kinase erbB-2 Interleukin-2 Mitogen-activated protein kinase kinase kinase 14 Pre-NOTCH Transcription and Translation Pantothenate kinase 2- mitochondrial Phospholipase C-gamma-1 Phosphodiesterase 6A IgE Fc receptor- alpha-subunit Ubiquitin carboxyl-terminal hydrolase 2 PI3K events in ERBB4 signaling MethioninePeptide N-myristoyltransferase aminopeptidaseNegativePhosphatidylinositol-3-4-5-trisphosphate regulation 1 of 1 FGFR3 signaling 5-phosphatase 1 Protein kinase C (PKC) Fatty acidActivation binding protein of adipocyte the TFAP2 (AP-2) familyPresenilin of transcription 2 factors Constitutive HistoneSignaling acetyltransferase by NOTCH1HDACs GCN5 deacetylatePEST Domain histones Mutants GrowthProtein factor receptor-bound farnesyltransferaseG protein-coupledRhodopsin protein kinase7 receptor betaGrowth kinase subunit 7 hormone receptor signaling 3-phosphoinositideCaspase-6 dependentToll-like proteinreceptor kinase-1 2 Kruppel-like factor 5 Signaling by FGFR3 fusions in cancer Serine/threonine-proteinSerine/threonine-proteinToll kinase Like kinase 24 MST4Receptor TLR6:TLR2 Cascade Peroxisome proliferator-activated receptor gamma/NuclearCREB-binding receptor protein/p53Cell coactivatordivision protein 3 kinase 8 Costimulation by the CD28 family Toll-likePlatelet-derived receptorPlatelet-derived (TLR7/TLR9) growth growthfactor receptorfactorPeptide receptor betaInterleukin-5 N-myristoyltransferase 2 Caspase-7 COUP transcriptionPerilipin-1Lysine-specific factor 2 histone demethylaseGamma-secretase 1 subunit PEN-2p75NTR negatively regulates cellNOTCH1 cycle via Intracellular SC1 Domain Regulates Transcription Coenzyme A biosynthesis PI3-kinase p110-delta/p85-alpha PhosphatidylinositolToll-like 3-kinase receptor catalytic 9subunit type 3 EZH2/SUZ12/EED complex DAP12 signaling Dual specificity mitogen-activated Activationprotein kinase kinaseLysine-specific of NF-kappaB 6 demethylase in B 4C cells LSD1/CoREST complex ConstitutiveNeurogenic Signaling locus notchby NOTCH1 homolog protein HD+PEST 1 Domain Mutants PI3-kinase class I GPVI-mediated activation cascade Interleukin-1 processing NADP-dependent malic enzyme Platelet-derived growth factor receptorNegative alpha regulation of FGFR1 signaling ISG15 antiviral mechanism Caspase-2Caspase-4 TNF-beta UDP-glucuronosyltransferaseBMAL1:CLOCK,NPAS2Alcohol sulfotransferase activates circadian 1-9 gene expression Regulation of signalingInterleukin-7 by CBL signaling Transfer of LPS from LBPMucosa-associated carrier to CD14 lymphoid tissue lymphoma translocation protein 1Histone-lysineHistone-lysine N-methyltransferase N-methyltransferase SUV420H2Carnitine SMYD3 Bilepalmitoyltransferase acidCytochrome receptor P450FXR 1A1 2 HATs acetylateNR1D1 histones (REV-ERBA) represses gene expression Caspase-9 Histone-lysineADAM17 N-methyltransferase SETD2 Prolactin receptor signalingTyrosine-protein kinase BTK Lysine-specificHistone-lysine demethylaseHistone-lysine N-methyltransferase-N-lysine N-methyltransferase methyltransferase 6B SETDB1H3 SMYD2lysine-79CytochromeFatty specific acid P450 desaturase 4A11 1 Histone acetyltransferase p300 Histone acetyltransferase PCAF CLEC7A (Dectin-1) signalingHistone-lysine N-methyltransferase- H3 lysine-36 and H4 lysine-20Long-chain specific fatty acid transport protein 1 RUNX3 regulates NOTCH signaling PI3-kinase p110-alpha/p85-alpha Interleukin-3, 5 and GM-CSF Negativesignaling regulation of FGFR2 signaling Histone-lysineHistone-lysine N-methyltransferase N-methyltransferase SUV39H1 SETD7 Signaling by FGFR3 point mutants in cancer Downstream TCR signalingFCERI mediated NF-kB activation N-lysine methyltransferase SETD8 Fatty acid-binding protein- liver Signaling by FGFR4 in disease Stem factor receptor PI3-kinase p110-gamma subunit Interleukin-1 receptor-associated kinase 3 Histone-lysine N-methyltransferase SUV39H2 Notch-HLH transcription pathway Role of LAT2/NTAL/LAB on calcium mobilizationPhosphatidylinositolPhosphatidylinositol-4-phosphatePhosphatidylinositol-4-phosphate 3-4-5-trisphosphate 3-kinase5-phosphatase 3-kinase C2 C2 domain-containing domain-containing 2 subunit subunit alpha gamma Protein kinase C theta Cell divisionVitamin cycleD3 receptor-interacting 2-like protein kinase 6 PI3K p110 beta/p85 alpha Signal transducer and activator of transcriptionProtein-tyrosine 5B phosphatase 1E Ubiquitin carboxyl-terminalPI5P Regulates hydrolase 4 TP53 Acetylation DNA-directedCaM RNA kinase polymerase- IV mitochondrial Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 Phosphatidylinositol-4-phosphatePhosphatidylinositol 3-kinaseCD28 4-kinase- C2 domain-containingdependent PI4K betaPI3K/Akt polypeptide signaling Mitogen-activated protein kinase kinase kinase 1 ETS-relatedNAD-dependent transcription factorATP Elf-3/Vitamin synthase deacetylasesubunitD3 receptor-interacting beta- mitochondrial proteinsirtuin (ESX/MED23) 3 PI4-kinaseProtein farnesyl/geranylgeranylProtein type II farnesyltransferase transferase Ubiquitin carboxyl-terminal hydrolase 21 PeroxisomeNAD-dependent proliferator-activated protein deacylase sirtuin-5- mitochondrial receptor gamma Tie2 Signaling Histone-lysine N-methyltransferase EZH2 Acetyl-CoALanosterol carboxylase synthase 2 SignalG beta:gamma transducer and activator signalling of transcription through 5A PI3Kgamma Low affinity neurotrophin receptor p75NTR Polycomb protein EED Acetyl-CoA carboxylase 1 Phosphatidylinositol-4-phosphateGeranylgeranyl 5-kinase transferase type-1 alpha type I Regulation of PTENNuclear receptor gene subfamily transcription 1 group D member 1 Signaling by FGFR2 in disease Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma Cytochrome P450 51 Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) Tyrosine-protein kinase BMX Inhibitor of Lysine-specificapoptosis protein demethylase 3 4B 7-dehydrocholesterolAcyl-CoA desaturase reductase PI3-kinase p110-alpha subunitInterleukinSignaling by receptor cytosolic SHC FGFR1 signaling fusion mutantsTyrosine-protein kinase LCK Probable ATP-dependent RNA helicase DHX36 HistoneLysine-specific lysine demethylase demethylase PHF8 4D Estrogen-related receptorElongation alpha of very long chain fatty acids protein 6 Downstream signal transduction T-cell-specific surface glycoprotein CD28 Advanced glycosylation end product-specificCLEC7A/inflammasome receptor pathway Lysine-specificLysine-specificLysine-specific demethylase demethylase demethylase 2A 4A 3A FarnesylAnti-estrogen diphosphate synthase (AEBS) Histone deacetylase 3/NCoR1 PI-3K Signalingcascade:FGFR3 by FGFR1 in disease Negative regulation of FGFR4 signaling DEx/H-box helicases activate type I IFN and inflammatory cytokines production Lysine-specific demethylase 5C GeranylgeranylSqualene pyrophosphate monooxygenase synthetase Basic fibroblast growth factor S-100 protein beta chainSerine/threonine-protein kinase RIPK2 Ubiquitin-conjugatingLysine-specific enzyme E2 N demethylase 5A ActivationSqualeneFattyDelta(14)-sterol acid synthetase synthaseof anterior reductase HOX genes in hindbrain development during early embryogenesis Nucleotide-binding oligomerization domain-containing protein 1 Mevalonate pyrophosphate decarboxylase Histone deacetylase 3 Apoptotic cleavage of cellular proteins CREB-binding protein PI-3K cascade:FGFR1 Phosphatidylinositol-5-phosphate 4-kinase type-2 beta Nucleotide-binding oligomerization domain-containing protein 2 Interleukin-1 family signaling Retinoic acid receptor beta YAP1- and WWTR1 (TAZ)-stimulated gene expression Protein-tyrosine phosphatase 2C RetinoicSterol acidregulatory receptor element-binding alpha protein 2 Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma Mixed lineage kinase domain-like protein Regulated proteolysis of p75NTR ConstitutivePI-3K Signalingcascade:FGFR2 by Aberrant PI3KPI5P, in Cancer PP2A and IER3 Regulate PI3K/AKT Signaling Phosphatidylinositol-5-phosphateSynthesis of PIPs in the nucleus 4-kinase type-2 alpha Nuclear factor NF-kappa-B complex Retinoic acid receptor gamma PI-3K cascade:FGFR4 PI3-kinase p110-beta subunit activated TAK1 mediates p38Nuclear MAPK factor NF-kappa-Bactivation p105 subunit PKMTs methylate histone lysines PI3-kinase p110-delta subunit Transcriptional regulation of white adipocyte differentiation Inactivation, recovery and regulationPIP3 ofactivates the phototransduction AKT signaling cascade PyruvatePyruvate dehydrogenase dehydrogenaseRetinoid X receptorkinase kinase isoform gamma isoformPPAR 2 3 delta/gamma Fibroblast growth factor receptor 4 Pyruvate dehydrogenase kinase isoform 4 Regulation of lipid metabolismRORA activatesby Peroxisome gene expression proliferator-activated receptor alpha (PPARalpha) Interleukin-1 receptor-associated kinase 4 PeroxisomePyruvate proliferator-activatedPyruvate dehydrogenase dehydrogenase receptor kinaseCarnitine isoformdelta O-palmitoyltransferase 1 PPARA 1- activatesliver isoform gene expression Fibroblast growth factor receptor IRAK4 deficiency (TLR2/4) Carnitine O-palmitoyltransferaseRetinoid X receptor 1- beta muscle isoform Nuclear receptor coactivator 1 PI3K Cascade Fibroblast growth factor 22 Toll-like receptorTumor 4/MD-2/CD14 necrosis factor ligand superfamily member 10 TRAF3-dependent IRF activation pathway PeroxisomePeroxisome proliferator-activated proliferator-activated receptor gamma/Nuclear receptor gamma/Nuclear receptor coactivator receptor coactivator 2 1 NF-kappaB inhibitor alpha Acidic fibroblast growth factor MyD88 deficiency (TLR2/4) Mitogen-activated protein kinase kinaseSerine/threonine-protein kinase 7 kinase TBK1 Histone-arginine methyltransferase CARM1 Interleukin-1 receptor-associated kinase 1 TAK1/TAB1InhibitorNuclear of nuclear factorIKK factor epsilon/TBK1 NF-kappa-B kappa B kinaseHDMs epsilon p65 demethylate subunitsubunit histones Peroxisome proliferator-activated receptor alpha Synthesis of PIPs at the plasma membrane MyD88-independent TLR3/TLR4TRAF6 cascade mediatedNF-kB NF-kBis activated activation and signals survival PPAR alpha/gamma NOD1/2Mitogen-activated Signaling protein Pathway kinase kinase kinase 7-interacting protein 1 RUNX3 regulates YAP1-mediated transcription IKBKG deficiency causes anhidrotic ectodermalIkBA variantInhibitor dysplasia leads of NF-kappa-B towith EDA-ID kinaseimmunodeficiency (IKK) (EDA-ID) (via TLR) Transcriptional activation of mitochondrial biogenesis MyD88:Mal cascade initiated on plasma membraneTNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway Retinoid X receptor alpha Inhibitor of nuclear factor kappa B kinase alphaTRAF6 subunit mediated IRF7 activation RXR alpha/PPAR gamma Myeloid differentiation primary response protein MyD88 Toll-like receptorReceptor-interacting 4 serine/threonine-protein kinase 3 NF-kappa-B essential modulator Toll-like receptor 4/MD-2 Baculoviral IAP repeat-containing protein 3 Activation of gene expression by SREBF (SREBP) TRAF6 mediated inductionTNF receptor-associatedof TAK1 complex factor 6 IRAK2 mediated activationTAK1 of TAK1activatesRIP-mediated complex NFkB by NFkB phosphorylationuponInhibitor activation BaculoviralTLR7/8 of nuclear viaand factororIAP ZBP1 9activation repeat-containingkappa stimulation B kinase of IKKsbeta subunitprotein complex 2 Ligand-dependent caspase activation cIAP1/cIAP2 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon Caspase-8Complex of retinoicTNFR1-induced acid binding NFkappaB(CRABPII) signaling and inhibitor pathway of apoptosis (cIAP1) proteins TRIF-mediated programmed cell death RegulationRegulation of necroptotic of TNFR1 cell deathsignaling Signaling by Retinoic Acid RIPK1-mediatedReceptor-interacting regulated necrosisserine/threonine-protein kinase 1

Toll-like receptor 3 IKK complex recruitment mediated by RIP1