Anti-STIL (C-terminal) polyclonal antibody (DPABH- 00595) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Immediate-early . Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Play a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1.

Immunogen Synthetic peptide within Human STIL aa 1250 to the C-terminus conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q15468

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB

Format Liquid

Size 100 μg

Buffer pH: 7.40; Constituent: PBS. Batches of this product that have a concentration

Preservative 0.02% Sodium Azide

Storage Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

GENE INFORMATION

Gene Name STIL SCL/TAL1 interrupting locus [ Homo sapiens ]

Official Symbol STIL

Synonyms STIL; SCL/TAL1 interrupting locus; SIL, TAL1 (SCL) interrupting locus; SCL-interrupting locus

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved ; MCPH7; TAL-1-interrupting locus protein; SIL; DKFZp686O09161;

Entrez Gene ID 6491

Protein Refseq NP_001041631

UniProt ID Q15468

Chromosome Location 1p32

Pathway Signaling events mediated by the Hedgehog family.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved