Anti-STIL (C-terminal) polyclonal antibody (DPABH- 00595) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Play a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1. Immunogen Synthetic peptide within Human STIL aa 1250 to the C-terminus conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q15468 Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Immunogen affinity purified Conjugate Unconjugated Applications WB Format Liquid Size 100 μg Buffer pH: 7.40; Constituent: PBS. Batches of this product that have a concentration Preservative 0.02% Sodium Azide Storage Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. GENE INFORMATION Gene Name STIL SCL/TAL1 interrupting locus [ Homo sapiens ] Official Symbol STIL Synonyms STIL; SCL/TAL1 interrupting locus; SIL, TAL1 (SCL) interrupting locus; SCL-interrupting locus 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved protein; MCPH7; TAL-1-interrupting locus protein; SIL; DKFZp686O09161; Entrez Gene ID 6491 Protein Refseq NP_001041631 UniProt ID Q15468 Chromosome Location 1p32 Pathway Signaling events mediated by the Hedgehog family. 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.