CURRICULUM VITAE

Qing Ouyang, Ph.D.

ADDRESS: Department of Molecular Biology, Cell Biology and Biochemistry, Institute for Brain Science, Brown University, 70 Ship Street, Providence, RI, 02903, USA Phone: 401-863-9766 (Lab) E-mail: [email protected] or [email protected]

RESEARCH EXPERIENCE:

07/2010-present: Investigator Department of Molecular Biology, Cell Biology and Biochemistry Brown University, Providence, RI 02903, USA

07/2009-06/2010: Postdoctoral Research Associate Department of Molecular Biology, Cell Biology and Biochemistry Brown University, Providence, RI 02903, USA

09/2006-06/2009: Research Associate Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14850, USA

09/2003-09/2006: Postdoctoral Associate Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14850, USA

9/1999-08/2003: Research Assistant Laboratory of Biotechnology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China

9/1996-8/1999: Research Assistant Laboratory of Genetics, Department of Biology, Xiamen University, Xiamen City, Fujian Province, China

PUBLICATIONS: 1. Morrow EM, Lizarraga SB, Ouyang Q. Novel endosomal mechanisms in human axonal growth mediated by Christianson syndrome protein NHE6. Int J Dev Neurosci. 2015 Dec; 47(Pt A):20. doi: 10.1016/j.ijdevneu.2015.04.063. 2. Qing Ouyang, Tojo Nakayama, Ozan Baytas, et. al. Mutations in mitochondrial enzyme GPT2 cause metabolic dysfunction and neurological disease with developmental and progressive features. Proceedings of the National Academy of Sciences of the United States of America (submission). 3. Qing Ouyang, Sofia B. Lizarraga, Michael Schmidt, Unikora Yang, Jingyi Gong, Debra Ellisor, Julie A. Kauer and Eric M. Morrow. Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development. Neuron, 2013, 80 (1):97-112 (Cover Page; Featured in Previews) 4. Qing Ouyang, Matthew Pescosolido, and Eric M. Morrow. Whole-genome sequencing identifies PDZRN3 mutation in pulmonary arterial hypertension. New England Journal of Medicine (in preparation) 5. Sofia B. Lizarrage, Qing Ouyang, Heather M. Thompson, and Eric M. Morrow. Endosomal Na+/H+ exchangers in Neurodevelopment and Disease. BioEssay (in preparation). 6. Ece D. Gamsiz, Qing Ouyang, Michael Schmidt, Shailender Nagpal, Eric M. Morrow. Genome-wide transcriptome analysis in murine neural retina using high- throughput RNA sequencing. Genomics, 2012, 99 (1):44-51. 7. Marie L. Goeritz, Qing Ouyang, and Ronald M. Harris-Warrick. Localization and function of Ih channels in a small neural network. J Neurophysiol, 2011, 106 (1): 44-58 8. Qing Ouyang, Vinay Patel, Jacqueline Vanderburgh and Ronald M. Harris- Warrick. Cloning and distribution of Ca2+-activated K+ channels in Lobster Panulirus interruptus. Neuroscience, 2010, 170(3):692-702 9. Hongnian Guo, Hanna Hou, Qing Ouyang and Jiahe Wu. Progress in the study and application of aphid-resistant genes. China Biotechnology, 2008, 28 (6): 118- 124 10. Qing Ouyang, Marie Goeritz, and Ronald M. Harris-Warrick. The Panulirus interruptus Ih-channel gene PIIH: modification of channel properties by alternative splicing and role in rhythmic activity. J Neurophysiol, 2007, 97(6):3880-3892 11. Xiaohu Kang, Qing Ouyang, Cunxiang Wu, Yuman Zhang, Yangnian Bai, Ziyi Cao, Wenqi Cai, Tianfu Han. Transformation of soybean with γ-TMT from Brassica oleracea for α-tocopherol elevation. Soybean Science, 2004, V23 (3): 236-238. 12. Yun Zhang, Qinglin Liu, Qing Ouyang, Wenqi Cai. Cloning of flower development associated MADS box gene fragments in Lilium. Acta Horticulturae Sinica, 2004, 31(3): 332-336 13. Hongnian Guo, Yantao Jia, Yonggang Zhou, Zhenshan Zhang, Qing Ouyang, Ying Jiang, Yingchuan Tian. Effects of transgenic tobacco plants expressing ACA gene from Amaranthus caudatus on the population development of Myzus persicae. Acta Botanica Sinica, 2004, 46 (9): 1100-1105 14. Qing Ouyang, Chuntao Fan, Hui Sun, Yuman Zhang, Shuangyi Bai, Wenqi Cai. Cloning and analysis of a γ-tocopherol methyltransferase gene from Brassica oleracea and the function of its recombinant protein. Progress in Natural Science, 2003, 13 (7): 17-22 15. Qing Ouyang, Wenqi Cai. Nature vitamin E biosynthesis pathway. Plant Physiology Communications. 2003, 39(5): 501-507 16. Shangyi Bai, Qinglin Liu, Qing Ouyang and Wenqi Cai. Differential display and sequence analysis of senescence-associated genes in cut roses. Journal of Agricultural Biotechnology, 2003, 11 (2): 154-157 17. Zhang J, Qin Y, Ouyang Q, Xu H, Zhou KF, Liu RH, Lou SL. Construction of shuttle expression vector and expression of thymosin alpha 1 in Synechococcus sp. PCC7942. Acta Biologiae Experimentalis Sinica, 2003, 36(1):1-4. 18. Qinglin Liu，Shuangyi Bai，Qing Ouyang，Hao Qu and Wenqi Cai. Cloning and sequence analysis of ethylene receptor ETR1 cDNA from cut roses. Acta Horticulturae Sinica，2002，29（4）：363-366 19. Guojie Mao, Qing Ouyang, Hui Sun, Wenqi Cai. Inhibitation activity of resveratrol on pathogenic fungi of tomato. Acta Phytopathologica Sinica, 2001, 31(3):139-140 20. Guojie Mao, Qing Ouyang, Wenqi Cai, et al. An effective DNA extraction method for PCR detection of transgenic tomato. Journal of Agricultural Biotechnology, 2001，9（4）：363-365 21. Jun Zhang, Yan Qin, Qing Ouyang, Hong Xu, et al. Construction of high level expression system by heat shock induced in cyanobacterium. High Technology Letters, 2001, 8: 17-21 22. Kefu Zhou, Jun Zhang, Tiansheng Chen, Hong Xu, Yan Qin, Qing Ouyang, et al. Preparation and determination of polyclonal antibody to thymosin α1. Chinese Journal of Immunology, 2001, 17 (1): 43-47

PRESENTATION AND POSTERS:

2005 Talk, “Cloning, characterization and localization of Ih in the STG”. Dynamic Neural Networks: The Stomatogastric Ganglion Meeting, Washington DC

2005 Poster 377.2, “Cloning, characterization and localization of Ih in the STG”. Q. Ouyang, M-L. Goeritz, R.M. Harris-Warrick; The Society for Neuroscience 35th Annual Meeting, Washington DC

2006 Poster 334.1, “Differential cAMP modulation of PIIH splice variants and overexpression of PIIH in the stomatogastric ganglion of Panulirus interruptus”. Q. Ouyang, R.M. Harris-Warrick; The Society for Neuroscience 36th Annual Meeting, Atlanta, GA

2007 Poster 407.8, “ Distribution of Ih channels and their role in synaptic integration in the stomatogastric ganglion of Panulirus Interruptus”. M-L. Goeritz, Q. Ouyang, R.M. Harris-Warrick; The Society for Neuroscience 37th Annual Meeting, San Diego, CA

2011 Poster 833F. “Novel Features of Neural Retina Transcriptome Revealed by High-throughput RNA-Sequencing.” E. Gamsiz, Q. Ouyang, M. Schmidt, S. Nagpal, E. Morrow; The 12th International Congress of Human Genetics & the American Society of Human Genetics 61st Annual Meeting. Montreal. Canada

2011 Poster. “Analysis of NHE6 expression during neuronal circuit development”. Sofia B. Lizarraga, Debra Ellisor, Michael Schmidt, Qing Ouyang, Eric M. Morrow. 14th Annual Research Symposium on Mental Health Sciences. Providence. RI.

2013 Poster. “The function of NHE6, a new autism-associated gene, during circuit development”. Qing Ouyang, Sofia B. Lizarraga, Michael Schmidt, Unikora Yang, Jingyi Gong, Debra Ellisor, Julie A. Kauer, Eric M. Morrow. 16th Annual Research Symposium on Mental Health Sciences. Providence. RI.

PATENT:

Wenqi Cai, Qing Ouyang, Tianfu Han, Hui Sun, Chuntao Fan, Yuman Zhang, et al. Brassica oleracea gamma-tocopherol methyltransferase (TMT) gene and it’s application. (Chinese patent: 02158079.0)

MANUSCRIPT REVIEWS

Served as Reviewer for the Following Journals:

Harvard Review of Psychiatry, BMC Neuroscience, PLOS ONE, Journal of Bioscience and Bioengineering, Protein & Cell, the Biological Bulletin, Chinese Science Bulletin, General Physiology and Biophysics, Journal of Biological Regulators and Homeostatic Agents

GENE SEQUENCES DISCOVERED:

Qing Ouyang, Vinay Patel, Jacqueline Vanderburgh and Ronald M. Harris-Warrick. Panulirus interruptus large conductance calcium-activated potassium channel splice variant L37 mRNA, complete cds, alternatively spliced. GenBank accession number: HM208587

Qing Ouyang and Ronald Harris-Warrick. Panulirus interruptus hyperpolarization- activated cyclic nucleotide-modulated cation channel splice variants (PIIH) mRNA; complete cds, alternatively spliced. GenBank accession number: DQ865250- DQ865259.

Qing Ouyang, Wenqi Cai, Shangyi Bai. Brassica oleracea gamma-tocopherol methyltransferase (TMT) mRNA; complete cds; nuclear gene for plastid product. GenBank accession number: AF381248

MEMBERSHIP

Society for Neuroscience New York Academy of Sciences

EDUCATION:

09/1999—2/2003: Ph.D. Major: Genetics Institute of Microbiology, Chinese Academy of Sciences (CAS), China 09/1996—08/1999: M.S Major: Botany Department of Biology, Xiamen University, China 09/1992—07/1996: B.S. Major: Biology College of Life Sciences, Central China Normal University, China