Anti-PREB Monoclonal Antibody, Clone FQS24363 (DCABH-7190) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-PREB monoclonal antibody, clone FQS24363 (DCABH-7190) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to PREB

Antigen Description Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription (By similarity). Guanine nucleotide exchange factor that activates SARA2. Required for the formation of COPII transport vesicles from the ER.

Immunogen Recombinant fragment within Human PREB aa 50-200. The exact sequence is proprietary.Database link: Q9HCU5

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Clone FQS24363

Purity Tissue culture supernatant

Conjugate Unconjugated

Applications WB, IHC-P, ICC/IF, IP

Positive Control HT-1376 and Raji cell lysates; Human colon and Human endometrial adenocarcinoma tissues; HT-1376 cells.

Format Liquid

Size 100 μl

Buffer Preservative: 0.01% Sodium azide; Constituents: 40% Glycerol, 0.05% BSA, 59% PBS

Preservative 0.01% Sodium Azide

Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name PREB prolactin regulatory element binding [ Homo sapiens ]

Official Symbol PREB

Synonyms PREB; prolactin regulatory element binding; prolactin regulatory element-binding protein; SEC12; prolactin regulatory binding-element protein; mammalian guanine nucleotide exchange factor mSec12; MGC3467;

Entrez Gene ID 10113

Protein Refseq NP_037520

UniProt ID Q9HCU5

Chromosome Location 2p23

Pathway Activation of Chaperone Genes by XBP1(S), organism-specific biosystem; Activation of Chaperones by IRE1alpha, organism-specific biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; COPII (Coat Protein 2) Mediated Vesicle Transport, organism- specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; ER to Golgi Transport, organism-specific biosystem.

Function DNA binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]