Conference Program Pierre Monsan Toulouse White Biotechnology, France
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Annual Report 2010 © Copyright 2011
Centre for Genomic Regulation Annual Report 2010 © Copyright 2011 Produced by: Department of Communication & Public Relations Centre for Genomic Regulation (CRG) Dr. Aiguader, 88 08003 Barcelona, Spain www.crg.eu Texts and graphics: CRG Researchers, Department of Communication and Public Relations Graphic Design: Genoma ArtStudio SCP (www.genoma-artstudio.com) Photography: Ivan Martí Printing: Novoprint, S.A. Legal deposit: B-24966-2011 CONTENTS CRG Scientific Structure 6 CRG Core Facilities Structure 8 CRG Management Structure 10 CRG Scientific Advisory Board (SAB) 12 CRG Business Board 13 Year Retrospect by the Director of the CRG: Miguel Beato 14 Research Programmes Gene Regulation 16 > Chromatin and gene expression 18 > Regulation of alternative pre-mRNA splicing during cell differentiation, development and disease 22 > Regulation of protein synthesis in eukaryotes 26 > Translational control of gene expression 29 Differentiation and Cancer 34 > Hematopoietic differentiation and stem cell biology 36 > Reprogramming and regeneration 40 > Epigenetics events in cancer 43 > Epithelial homeostasis and cancer 48 > Mechanisms of cancer and aging 51 Genes and Disease 54 > Genetic causes of disease 56 > Gene therapy 65 > Gene Function and murine models of disease 69 > Neurobehavioral phenotyping of mouse models of disease 73 > Genomic and epigenomic variation in disease 77 Bioinformatics and Genomics 82 > Bioinformatics and genomics 84 > Comparative bioinformatics 92 > Comparative genomics 96 > Evolutionary genomics 101 > Gene function and evolution -
YOUNG SCIENTISTS FORUM Invited Presenters Profiles
YOUNG SCIENTISTS FORUM Invited Presenters Profiles Dr. Bruna Costa, Post-Doctoral Researcher PhD in Materials Science and Technology (2018) Faculty of Dentistry, Univesity of São Paulo (USP) Alameda Dr. Octávio Pinheiro Brisolla, 17012-901 Bauru, SP, Brazil. School of Sciences, São Paulo State University (UNESP) Av. Engenheiro Luiz Edmundo Carrijo Coube, 17033-360, Bauru, SP, Brazil. e-mail: [email protected] https://publons.com/researcher/3024137/bruna-costa/ Dr. Paulo Noronha Lisboa-Filho, Associate Professor Brazilian Branch of the Institute of Biomaterials, Tribocorrosion and Nanomedicine Physics Department, School of Sciences São Paulo State University (UNESP) Av. Engenheiro Luiz Edmundo Carrijo Coube, 17033-360, Bauru, SP, Brazil. e-mail: [email protected] https://unesp.br/portaldocentes/docentes/414/repositorio Dr. Bruna Costa concluded her PhD in 2018 under supervision of Prof. Paulo Noronha Lisboa-Filho. Her research was focused on Biomaterials, specifically biological effects associated to titanium-based wear products (and their physicochemical properties) regarding human bone cells. Special attention was also given to vanadium compounds possibly generated from Ti-6Al-4V biomedical alloys. During her PhD, she spent one-year abroad in three different institutions in Portugal (University of Minho, University of Porto and International Iberian Nanotechnology Laboratory). Prof. Paulo Noronha Lisboa-Filho is the head of Advanced Materials and Nanotechnology Laboratory at São Paulo State University, Bauru, São Paulo, Brazil. Following different research lines, his work is mainly focused on titanium (orthopedics and dental) implants surface modification for improved osseointegration, antibacterial properties and degradation resistance. Strongly devoted to dental applications, he also works with ceramic materials and metalorganic frameworks for specific enzyme immobilization and release. -
Seminar 2021 | א“פשת רנימס
סמינר תשפ“א | Seminar 2021 Adams Seminar 2021 סמינר אדמס תשפ“א Guest Lecturer Prof. Daniel A. Chamovitz Professor of Plant Pathology President, Ben-Gurion University of the Negev Editors Deborah Greniman, Bob Lapidot Photographer Michal Fattal Graphic Design Navi Katzman-Kaduri The Israel Academy of Sciences and Humanities P.O.Box 4040 Jerusalem 9104001 Tel 972-2-5676207 E-mail [email protected] www.adams.academy.ac.il The Adams Fellowships is a joint program of the late Mr. Marcel Adams of Canada and the Israel Academy of Sciences and Humanities. Chartered by law in 1961, the Israel Academy of Sciences and Humanities acts as a national focal point for Israeli scholarship in both the natural sciences and the humanities and social sciences. The Academy consists of approximately 135 of Israel’s most distinguished scientists and scholars, who, with the help of the Academy’s staff and committees, monitor and promote Israeli intellectual excellence, advise the government on scientific planning, fund and publish research of lasting merit, and maintain active contact with the broader international scientific and scholarly community. For more information, please send an e-mail to [email protected] or call 972-2-5676207. Visit our website: adams.academy.ac.il Adams Seminar 2021 | 3 Adams Fellowships Marcel Adams Hebrew-speaking philanthropist Marcel Adams, who escaped from a forced-labor camp in Romania in 1944, fought in Israel’s War of Independence and made his fortune in Montreal, has endowed the Adams Fellowship Program to support Israel’s brightest doctoral students in the natural and exact sciences each year. -
EMBO Facts & Figures
excellence in life sciences young investigators|courses,workshops,conference series & symposia|installation grantees|long-term fellows|short-term fellows|policy, science & society|the EMBO Journal|EMBO reports|molecular systems biology|EMBO molecular medicine|global exchange|gold medal|the EMBO meeting|women in science| EMBO reports|molecular systems biology|EMBO molecular medicine|global exchange|gold medal|the EMBO meeting|women in science|young investigators|courses,workshops,conference series & symposia|installation grantees|long-term fellows|short-term fellows|policy, science & society|the EMBO Journal| global exchange|gold medal|the EMBO meeting|women in science|young investigators|long-term fellows|short-term fellows|policy, science & society|the EMBO Journal|courses,workshops,conference series & symposia|EMBO reports|molecular systems biology|EMBO molecular medicine|installation grantees| EMBO molecular medicine|installation grantees|long-term fellows|gold medal|molecular systems biology|short-term fellows|the EMBO meeting|womenReykjavik in science|young investigators|courses,workshops,conference series & symposia|global exchange|EMBO reports|policy, science & society|the EMBO Journal| gold medal|the EMBO meeting|women in science|young investigators|courses,workshops,conference series & symposia|global exchange|policy, science & society|the EMBO Journal|EMBO reports|molecular systems biology|EMBO molecular medicine|installation grantees|long-term fellows|short-term fellows| courses,workshops,conference series & symposia|global -
Keynote and Invited Presenters PROFILES Employing Physical
Keynote and Invited Presenters PROFILES Prof. Dr. Bert Mueller, Thomas Straumann Chair Director of the Biomaterials Science Center (BMC) The University of Basel, Gewerbestrasse 14, 4123 Allschwil, Switzerland, Email: [email protected], www.bmc.unibas.ch Prof. Dr. Bert Müller has been Thomas Straumann-Chair for Materials Science in Medicine at the University of Basel, Switzerland, since September 2006. In 1994, he obtained a Ph.D. in experimental physics from the University of Hannover, Germany. For his achievements, he was granted with the Morton M. Traum Award of the American Vacuum Society. Since April 2001, he has been teaching as faculty member of the Physics Department at ETH Zurich. The Biomaterials Science Center, founded by Müller in March 2007, hosts researchers from many fields dealing with nanotechnology-based artificial muscles for incontinence treatment, compliant electrodes for brain stimulation, mechano-responsive nano-containers for targeted drug delivery for the treatment of cardiovascular diseases, highresolution X-ray imaging to visualize the human body down to the molecular level in health and disease, and further applications of nanosciences in medicine and dentistry. The mission of the research team can be summarized by employing physical principles for human health. Professor Müller is author of more than 300 publications in a wide variety of journals, many of them have been the result of doctoral thesis he supervised in the fields of medicine, dentistry, physics, nanosciences, and biomedical engineering. In 2014, he was elected as Fellow of SPIE and in 2015 as an active member of the European Academy of Sciences and Arts. The activity in the E-MRS: Professor Dr. -
CURRICULUM VITAE October 201 7 A
MICHAL SHARON CURRICULUM VITAE October 201 7 A. PERSONAL DETAILS Date of Birth: March 25th 1972 Country of Birth: Israel Citizenship: Israeli, German Marital Status: Married, +3 (Ori 1998, Naama 2001, Ronni 2007) Phone: +972-8-9343947 Fax: +972-8-9346010 E-mail: [email protected] Webpage: http://www.weizmann.ac.il/Biomolecular_Sciences/MichalSharon/home B. EDUCATION 2003-2006 Post-doctoral research under Prof. Carol V. Robinson, Department of Chemistry, University of Cambridge, Cambridge, UK. Field of study: Mass spectrometry of large non-covalent complexes. 1996-2003 M.Sc./Ph.D. combined program (direct PhD) under Prof. Jacob Anglister, Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel. Field of study: Three-dimensional structure determination of protein complexes using multidimensional NMR Thesis title: Suggested mechanism for HIV-1 coreceptor selectivity unveiled by the NMR structure of a V3MN peptide in complex with a human neutralizing antibody. 1993-1996 B.Sc. Chemistry, The Hebrew University, Jerusalem, Israel, Cum laude. C. EMPLOYMENT 2015-present Associate Professor at the Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel. 2007-2015 Senior Scientist (equivalent to Assistant Professor) at the Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel. 2006-2007 Royal Society Research Fellow, Department of Chemistry, University of Cambridge, Cambridge, UK. D. ACADEMIC ADMINISTRATION 2017-2021 Vice-President, ILANIT/FISEB -
Dan Tawfik: in Memoriam
INFERENCE / Vol. 6, No. 2 Dan Tawfik In Memoriam Anthony Futerman an tawfik passed away in early May 2021 while I remember sneaking out one lunchtime to a well-known on a climbing trip in Croatia. He was sixty-five restaurant with some of my students and finding Dan and yet at the height of his powers. Dan was a regaling his colleagues at the next table, a great hummus Dfaculty member at the Weizmann Institute of Science, and mound shrinking on his plate.1 for the last twenty years or so, we were colleagues in the On May 9, we all knew that we would miss him, and we Department of Biomolecular Sciences. I knew him well were right. and I admired his work. Dan was a second-generation Dan’s scientific research focused on proteins and, in Israeli, the son of Iraqi Jewish immigrants. As a young particular, on enzyme evolution. The majority of his work man, he served in the Israeli air force, reaching the rank of was concerned with how new protein functions evolved major before studying chemistry and biochemistry at the from existing functional proteins. More recently he had Hebrew University of Jerusalem. Dan completed his bach- begun working on the most difficult challenge in biochem- elor of science in 1988 and his master of science in 1990. ical evolution: reconstructing the metabolic pathways that He then enrolled in the PhD program at the Weizmann may have led to the emergence of the first functional pro- Institute, joining a research project supervised by Michael teins. -
Structural Biology: the Molecular Fabric of Life
האקדמיה הלאומית הישראלית למדעים והחברה המלכותית הבריטית מתכבדות להזמינכם לכינוס משותף בנושא The Israel Academy of Sciences and Humanities and the Royal Society cordially invite you to a Joint Conference on Structural Biology: The Molecular Fabric of Life שני-שלישי, כ״ט-ל׳ בשבט תש״ף Monday-Tuesday, February 24-25, 2020 Steering Committee: Richard Henderson, Nathan Nelson, Venki Ramakrishnan, Joel Sussman Program Monday, February 24, 2020 Tuesday, February 25, 2020 Chairperson: Nathan Nelson, Tel Aviv University Chairperson: Joel L. Sussman, Weizmann Institute of Science 0830 Gathering 0830 Gathering 0900 Welcome SESSION IV Nili Cohen, President, Israel Academy of Sciences and Humanities Biology as a Data Science and Its Impact on Venki Ramakrishnan, President, The Royal Society Protein Evolution H.E. Ambassador Neil Wigan OBE, British Ambassador to Israel 0900 M. Madan Babu, MRC Laboratory of Molecular Biology, Cambridge Data Science Approaches to Biological Systems 0915 Keynote Lecture Ada Yonath, Weizmann Institute of Science 0945 Dan Tawfik, Weizmann Institute of Science Origin of Life, Next Generation Eco Friendly Antibiotics, and a Protein Evolution – From So Simple a Beginning Connection between Pathogenicity & Evolution 1030 Sarel Fleishman, Weizmann Institute of Science Evolution-Guided Atomistic Design of New and Improved SESSION I Protein Activities Protein Machines on the Membrane 1115 Break 1000 Gabriel Waksman, Birkbeck, University of London SESSION V Mechanism of a Protein Polymerisation Machine at the Mechanism and Regulation -
Enzyme Engineering XXIII
Program Enzyme Engineering XXIII September 6 – 11, 2015 St. Petersburg, Florida, USA Conference Co-Chairs Jon Dale Stewart University of Florida USA Robert DiCosimo DuPont Industrial Biosciences USA Engineering Conferences International 32 Broadway, Suite 314 New York, NY 10004, USA Phone: 1-212-514-6760 www.engconfintl.org – [email protected] The Vinoy® Renaissance St. Petersburg Resort & Golf Club 501 5th Avenue NE St. Petersburg, Florida 33701 USA Tel: +1-727-894-1000 Engineering Conferences International (ECI) is a not-for-profit global engineering conferences program, originally established in 1962, that provides opportunities for the exploration of problems and issues of concern to engineers and scientists from many disciplines. ECI BOARD MEMBERS Barry C. Buckland, President Mike Betenbaugh Nick Clesceri Peter Gray Michael King Raymond McCabe David Robinson Eugene Schaefer P. Somasundaran Chair of ECI Conferences Committee: Nick Clesceri ECI Technical Liaison for this conference: Jeff Moore ECI Executive Director: Barbara K. Hickernell ECI Associate Director: Kevin M. Korpics ©Engineering Conferences International Enzyme Engineering Steering Committee Yasuhisa Asano, Toyama Prefectural University Robert DiCosimo, DuPont Industrial Biosciences Pierre Monsan, INSA Toulouse Jeff Moore, Merck and Co., Inc. Jun Ogawa, Kyoto University Magali Remaud-Simeon, Universite de Toulouse Jon Stewart, University of Florida Yoshihiko Yasohara, Kaneka Corporation, Japan Professor Dan S. Tawfik Winner of the 2015 Enzyme Engineering Award Since 1983 the Enzyme Engineering Award has been presented at ECI’s biennial International Enzyme Engineering Conference. The 2015 Award will be presented at the 23rd Enzyme Engineering Conference in St Petersburg, Florida. This award recognizes outstanding achievement in the field of enzyme engineering, through basic or applied research in academia or industry. -
Engineering Proteins from Sequence Statistics: Identifying and Understanding the Roles
Engineering Proteins from Sequence Statistics: Identifying and Understanding the Roles of Conservation and Correlation in Triosephosphate Isomerase DISSERTATION Presented in Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy in the Graduate School of The Ohio State University By Brandon Joseph Sullivan B.S. Graduate Program in the Ohio State Biochemistry Program The Ohio State University 2011 Dissertation Committee: Thomas J. Magliery, Advisor Mark P. Foster William C. Ray Copyright by Brandon Joseph Sullivan 2011 Abstract The structure, function and dynamics of proteins are determined by the physical and chemical properties of their amino acids. Unfortunately, the information encapsulated within a position or between positions is poorly understood. Multiple sequence alignments of protein families allow us to interrogate these questions statistically. Here, we describe the characterization of bioinformatically-designed variants of triosephosphate isomerase (TIM). First, we review the state-of-the-art for engineering proteins with increased stability. We examine two methodologies that benefit from the availability of large numbers - high-throughput screening and sequence statistics of protein families. Second, we have deconvoluted what properties are encoded within a position (conservation) and between positions (correlations) by designing TIMs in which each position is the most common amino acid in the multiple sequence alignment. We found that a consensus TIM from a raw sequence database performs the complex isomerization reaction with weak activity as a dynamic molten globule. Furthermore, we have confirmed that the monomeric species is the catalytically active conformation despite being designed from 600+ dimeric proteins. A second consensus TIM from a curated dataset is well folded, has wild-type activity and is dimeric, but it only differs from the raw consensus TIM at 35 nonconserved positions. -
Feinberg Graduate School 2012 Graduates Feinberg Graduate School
Feinberg Graduate School 2012 Graduates Feinberg Graduate School Weizmann Institute of Science P.O. Box 26, Rehovot 76100, Israel Phone: + 972-8-934-2924 Fax: + 972-8-934-4114 E-mail: [email protected] http://www.weizmann.ac.il/pages/feinberg-graduate-school Department of Resource Development Phone: + 972-8-934-4582 Fax: + 972-8-934-4155 E-mail: [email protected] Photography: Weizmann Institute Photography Lab Israel Sun Ltd. Production & Design: www.dio-olamot.com Weizmann Institute of Science | Feinberg Graduate School | 2012 Graduates The Weizmann Institute of Science Contents The Feinberg Graduate School Prizes for Outstanding Students Competitive Fellowships PhD Recipients MSc Recipients Non-thesis MSc in Science Teaching Recipients With gratitude to the supporters of the Feinberg Graduate School at the Weizmann Institute of Science Scholarship Awards PhD Scholarships in Perpetuity Scholarship Awards MSc Scholarships in Perpetuity Weizmann Institute of Science | Feinberg Graduate School | 2012 Graduates The Weizmann Institute of Science is one of the world’s leading institutes The for basic scientific research in all disciplines of natural and exact sciences: mathematics and computer sciences; physics; chemistry; biochemistry and biology. At any given time, some 1,200 studies are being conducted Weizmann at the Weizmann Institute in fields that are on the cutting edge of science and that serve to enrich human knowledge about the world around us Institute of and our role in the universe. The Institute’s unique character encourages numerous multidisciplinary collaborations in all areas of research. The Science scientific investigations conducted at the Weizmann Institute makes a major contribution to the development of new technologies and to the invention of new materials, medicines, and state-of-the-art medical treatment, and to better understanding the environment and developing alternative sources of energy. -
SMART NANO-MATERIALS and SYSTEMS STRATEGY from NATURE the Online Virtual Forum Invited Presenters Mon. 9.00 -18.00 H., 31St May, 2021
SMART NANO-MATERIALS and SYSTEMS STRATEGY from NATURE The online Virtual Forum Invited Presenters st Mon. 9.00 -18.00 h., 31 May, 2021 The E-MRS Invited Organizers/Chairs Professors Dr. Emmanuel STRATAKIS and Insung S. CHOI With supporting this event as Guest Editors in the Special Issues of International Journal of Molecular Sciences entitled “Natural and Biomimetic Functional Materials” (Prof. Dr. Emm. Stratakis’s project) International Journal of Nanomedicine entitled “Frontier Research in Biomaterials and Nanomedicine” (Prof. Dr. Insung S.Choi’s project) Emmanuel Stratakis Adj. Prof. Dr. Head of the Ultrafast Laser Micro and Nano Processing Laboratory Institute of Electronic Structure and Laser (IESL), Director of the European Nanoscience Facility of FORTH University of Crete, Heraklion 714 09, Greece E-mail: [email protected] web-site: http://www.iesl.forth.gr/ULMNP , http://stratakislab.iesl.forth.gr/team/emmanuel-stratakis/ Insung S. Choi Prof., Dr. Director of the Center for Cell-Encapsulation Research, Department of Chemistry, KAIST, Daejeon 34141, KOREA E-mail: [email protected] Web site: http://cisgroup.kaist.ac.kr 1. Emmanuel Stratakis 9.00 h. (O.1.1)- CONTROL ID number BPF7K Emmanuel Stratakis Adj. Prof. Dr. Research Director of the Ultrafast Laser Micro- and Nano- Processing Lab, Institute of Electronic Structure and Laser (IESL), University of Crete, Heraklion 714 09, Greece Head of the Ultrafast Laser Micro- and Nano-Processing Lab. National Representative to the Program Committee of EU on Nanosciences, Nanotechnology and Advanced Materials Member of the Scientific Committee of COST Director of the European Nanoscience Facility of FORTH, part of the NFFA-Europe P.O.