Fifth Annual World Congress on Industrial Biotechnology and Bioprocessing Linking Biotechnology, Chemistry and Agriculture to Create New Value Chains
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Summary Proceedings Fifth Annual World Congress on Industrial Biotechnology and Bioprocessing Linking Biotechnology, Chemistry and Agriculture to Create New Value Chains Chicago, April 27–30, 2008 Summary Proceedings Fifth Annual World Congress on Industrial Biotechnology and Bioprocessing ©2008 National Agricultural Biotechnology Council Not for Sale (request a free copy) Foreword and Acknowledgments he Fifth Annual World Congress on Industrial Biotechnology and Bioprocessing convened Tin Chicago, April 27–30, 2008, organized by the Biotechnology Industry Organization (BIO), the American Chemical Society (ACS), the National Agricultural Biotechnology Coun- cil (NABC), the US Department of Energy (DOE) and the DOE’s Genomics:GTL Program. Some 170 presentations were made in six plenary and ten “break-out” sessions (each with fi ve parallel tracks); fi fty-fi ve presentations were made as posters and six workshops were held. This was the best-attended World Conference to date, with 1,100 delegates. The organizers are grateful to BIOTECanada and EuropaBio as supporting organizations, to Industrial Biotechnology as the media sponsor, and to the many conference sponsors. Par- ticular thanks are due the program committee for their hard work and dedication in screening submissions, locating speakers and in organizing a very dynamic program: George Anderl, Roland Andersson, Rich Burlingame, Bruce Dale, Allen Dines, Larry Drumm, Raymond Dry- malski, John Finley, John Frost, Richard Gross, Jack Grushcow, Ralph Hardy, Jack Huttner, James Iademarco, James Lalonde, Sophie Laury, Birgit Kamm, Mike Ladisch, David Lee, Eric Mathur, Jim Millis, Ramani Narayan, Glenn Nedwin, Erin O’Driscoll, Adrien Pilon, William Provine, John Ranieri, Maria Rapoza, Anna Rath, Manfred Ringpfeil, Gerson Santos, Philip Schwab, Garrett Screws, James Seiber, James Stoppert, Mark Stowers, Larry Walker, David Ward, Roger Wyse, James Zhang and Paul Zorner. The indefatigable efforts behind the scenes and careful organizational oversight of Matthew Carr, Amy Ehlers, Jocelyn Modine, Courtney Murray and Kimberly Scherr (BIO) were vital to the seamless success of the conference. This Summary Proceedings provides broad coverage of the plenary presentations and brief highlights from the breakout sessions. It is largely the product of fi rst-rate work by Marie Don- nelly, Ben Heavner, Navaneetha Santhanam (Cornell University) and Brandon Charles (BIO) as recorders. And thanks are due Susanne Lipari (NABC) for her excellent page-layout/design work. Allan Eaglesham Executive Director, NABC Summary Proceedings Editor August, 2008 Contents Welcoming Remarks ...............................................................................................1 Brent Erickson, Jim Greenwood Plenary Sessions .....................................................................................................3 Industrial Biotechnology: Outlook for 2008 ..............................................................3 Jacques Beaudry-Losique, Roger Wyse Industrial Biotechnology: Growing the Global Economy ..........................................6 David Morris, Wei-Ming Jiang, David Berry A Taste of the Future: Innovation in Food Ingredients and Flavorings ...................10 Kent Snyder, Tjerk de Ruiter, Pradip Mukerji Views from the Top: CEO Perspectives on the Evolution of the Industrial-Biotechnology Value Chain ..........................................................12 Richard Hamilton, Jeff Broin, Steen Riisgaard Industrial Biotechnology: Sustainable Climate-Change Solutions .........................15 Steve Koonin, Mauro Gregorio, Michael Walsh Synthetic Genomics: Solutions and Challenges ....................................................19 James Newcomb, Jack Newman, Robert Friedman Breakout Sessions.................................................................................................23 Biofuels and Bioenergy ..........................................................................................23 The US Department of Energy Bioenergy Research Centers: Accelerating Transformational Breakthroughs for Biofuels Production ..............23 Advancing Enzymatic Hydrolysis of Lignocellulosic Biomass ............................23 Creation and Commercialization of Next-Generation Advanced Biofuels ..........24 Comparison of Key Conversion and Feedstock Technologies ...........................24 Biofuels in Aviation .............................................................................................25 International Developments in Cellulosic Biomass Technologies ......................25 Joint Process Developments in Biomass ...........................................................26 Biofuels Technology to Address Climate Change ..............................................26 Biofuels from Microalgeae .................................................................................27 Linking the Pulp and Paper Industry with Lignocellulose Bioconversion ...........27 Renewable Feedstocks..........................................................................................28 The Business of Bioenergy from Purpose-Grown Trees and Other Woody Biomass Cellulase Expression in Plants ...............................28 Cellulase Expression in Plants ...........................................................................28 Feedstock: From the Farm to the Bioref nery Gate ............................................29 Algae For Energy ...............................................................................................29 Swedish Developments in Industrial Biotechnology ..........................................30 Capitalizing on Biomass: A Comparison of Energy-Crop Economics for the Bio-Revolution ......................................................................30 Fractionation, Pretreatment and Hydrolysis .......................................................30 Seed Oils as Industrial Feedstocks ....................................................................31 New Fuel-Crop Alternatives ...............................................................................31 Harvest, Storage, and Transportation of Biomass .............................................31 Renewable Chemicals and Biomaterials ................................................................32 Polyhydroxyalkanoates: Plastics of the Future ..................................................32 Activities Along the Industrial Biotech Value Chain for Renewable Chemicals in Germany ....................................................................32 Advances in Crop Biofactories in Australia ........................................................33 Nanobiomaterials ...............................................................................................34 Biomaterials in the Automotive Sector ...............................................................34 Conversion of Renewable Feedstocks to Chemicals Beyond Fuels in a High Crude-Oil-Price World: Perspectives for the Future Biobased Economy .................................................................................35 “White” Biotechnology: From Building Blocks to Bioterials ................................36 Advances in Biobased Chemicals Production ...................................................37 From Polyols to Propylene Glycol ......................................................................37 Converting Lignocellulose into Biochemicals .....................................................38 Fine Chemicals, Food Ingredients and Pharmaceuticals .......................................39 Cell Factories for Fine Chemicals and Vaccines ................................................39 New Sources of Biopharmaceuticals .................................................................40 Advances in Biocatalysis ...................................................................................40 Industrial Biotechnology Boosting the Food & Drinks Chain: From Science to Product ...................................................................................41 Biotech in Big Pharma—“Red” Biotech..............................................................41 Production of Nutraceutical Ingredients Using “White” Biotechnology Processes...................................................................................42 Genomics for Food, Nutrition and Personalized Medicine.................................43 Biotech in the Fine Chemical Sector: “White” Biotechnology .............................43 Advances in Food Processing and Ingredients ..................................................44 Biotech Production of Cosmetics and Fragrance ...............................................44 Business Development, Infrastructure and Public Policy .......................................45 Ensuring the Sustainable Development of Biobased Industries ........................45 Partnerships for Successful Development of the Forest Bioref nery ..................45 Aligning Technologies to Address Market Drivers for Renewable Biobased Products ..........................................................................46 Increasing the Public’s Understanding of Industrial Biotechnology: What’s the Story? ...............................................................................................46 Economic and Environmental Indicators of the Biobased Economy ..................47 US Energy and Agriculture Policy Update: Federal and State ...........................48 Building Incentives for Biotech Industrial and