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Isscr 2013 Program Book 11TH ANNUAL MEEtiNG, BostoN, MA USA ™ BD LSRFortessa X-20 with BD reagents Dear Colleagues: A brilliant new approach to multicolor cell analysis on the benchtop. On behalf of the International Society for Stem Cell Research, we are delighted to welcome you to our 11th Annual Meeting, the largest forum for stem cell and regenerative medicine professionals from around the world. It is also a pleasure to be back in Boston, a historic city that played a key role in the ISSCR’s development, and which features a vibrant stem cell research, biotech, and life science research community. The primary goal of our annual meeting is to provide you with an unparalleled array of opportunities to learn from and interact with your peers, and this year you’ll have more ways to do that than ever before. Additional Poster Session We enjoyed a record number of submitted poster abstracts for 2013. In response to past attendees’ requests for additional time to view and discuss poster presentations, we’ve added a third poster session, giving you a quick and efficient way to keep abreast of the latest scientific advances. “Poster Teasers” and New “Poster Briefs” In 2011, we introduced “poster teasers,” which gave delegates time to share their findings in plenary sessions via 1-minute discussions. They’ve proved so popular with attendees that this year, we’re adding “poster briefs,” 3-minute mini-presentations that give authors of the most highly-rated poster abstracts an opportunity to discuss their work during the concurrent sessions. The burgeoning interest in stem cell research is reflected in our record number of exhibitors this year, 26% of whom are new. They make our meeting possible, and we encourage you to visit them and investigate all the tools and services they offer. ISSCR’s New Mobile Application and Journal With so much to see, it’s critical to manage your time here wisely. To that end, we are introducing the ISSCR2013 mobile application. Use it to access meeting information, and to search abstracts to find the scientific content of most interest to you. And finally, we are proud to launch the new ISSCR journal, Stem Cell Reports, which is intended to further the exchange of information related to stem cell research and heighten the visibility Designed for limited space of researchers. During the meeting, you’ll have a chance to speak with the editors. We hope you’ll consider submitting a manuscript and, if you’re presenting at our meeting, that you’ll keep and boundless potential. Stem Cell Reports in mind when it’s time to publish your data. Get the most from the BD LSRFortessa™ X-20 with its performance class. It can be configured with high-quality BD reagents for boundless potential up to 5 lasers, with a choice of 14 wavelengths As always, we are grateful for your support. Thank you for coming -- we believe you’ll agree that for your discoveries. and up to 20 detector positions, simultaneously The full range of reagent choices from detecting up to 20 parameters. this year’s meeting offers you an unprecedented opportunity to gain a comprehensive understanding BD Biosciences now includes antibodies conjugated From the exploration of cellular features to of our important and dynamic field. to BD Horizon™ Brilliant Violet™ polymer dyes, the characterization of cells through surface, acquired from Sirigen, that are four to ten times intracellular, or secreted markers, BD delivers value, brighter than conventional dyes. Optimized for use choice, and performance. on the BD LSRFortessa X-20, Brilliant Violet dyes The BD LSRFortessa X-20 and BD research reagents deliver exceptional choice and performance for represent the new face of benchtop cell anal ysis. multicolor panel design. Explore the brightest ideas in cell analysis at The BD LSRFortessa X-20 is an affordably priced bdbiosciences.com/go/fortessa. powerhouse with the most compact footprint in Class 1 Laser Product. For Research Use Only. Not for use in diagnostic or therapeutic procedures. Alexa Fluor® is a registered trademark of Life Technologies Corporation. George Q. Daley MD, PhD Shinya Yamanaka MD, PhD Cy™ is a trademark of GE Healthcare Biosciences Corp. Cy™ dyes are subject to proprietary rights of GE Healthcare Biosciences Corp and Carnegie Mellon BD Biosciences ProGram CHair PREsidENT University and are made and sold under license from GE Healthcare Biosciences Corp only for research and in vitro diagnostic use. Any other use requires a commercial sublicense from GE Healthcare Biosciences Corp, 800 Centennial Avenue, Piscataway, NJ 08855-1327, USA. CF™ is a trademark of Biotium, Inc. 2350 Qume Drive BD, BD Logo and all other trademarks are property of Becton, Dickinson and Company. © 2013 BD San Jose, CA 95131 23-14837-01 bdbiosciences.com isscr.org/2013 i INTERNatioNAL SociETY for STEM CELL RESEarcH 11TH ANNUAL MEEtiNG, BostoN, MA USA TAblE OF CONTENts Letters of Welcome. i, ii, 9, 10 ISSCR 11th Annual Meeting Supporters. 1 Special Events. 2 General Information. .3-4 2013 Featured Speakers. 5-6 Dear Friends, 2013 ISSCR Awards. .7 On behalf of the Harvard Stem Cell Institute and our many colleagues in the Boston area, we are ISSCR Leadership. .8 pleased to welcome you to the 11th Annual Meeting of the International Society for Stem Cell Mobile App Guide. .11 Research. It is only fitting that ten years after the ISSCR’s first annual meeting in Washington, DC Program Schedule that the meeting is in Boston where the idea for ISSCR was first launched. Tuesday June 11th. 12 Wednesday June 12th. .12-14 Since its inception, ISSCR has recognized that stem cell research is inherently a multi-disciplinary Thursday June 13th . 14-25 effort that transcends geographic, organizational and domain boundaries. Over those years, Friday June 14th. .25-31 progress in that science has sometimes been frustratingly slow; other times, unforeseen break- Saturday June 15th . 31-32 throughs have advanced the pace of discovery amazingly quickly. The award of this year’s Nobel Prize in Medicine to Drs. Gurdon and Yamanaka demonstrates that our field is no longer just a ISSCR Travel Awards. .13 potentially interesting idea, but is fundamental to the future of science and medicine. As we ISSCR Committees. .17 collectively share our recent results and new ideas with one another over the next several days, ISSCR Abstract Reviewers. .19 we can only be even more excited about what the next ten years will bring. Exhibit Booth Floor Plan. 34 Poster Floor plan. 35-36 HSCI is delighted to welcome you to the vibrant eco-system of the Boston area stem cell and life Exhibitors Alphabetical by Company Name. .37-38 sciences community that will be home for the next few days to the larger, global eco-system of Exhibitors by Stand Number. 39-40 stem cell science that is ISSCR. Exhibitor/Supporter Directory. .42 Program and Abstracts Wednesday June 12th. 56-57 We hope you have a productive meeting and enjoyable time. Thursday June 13th . 57-77 Friday June 14th. .77-98 Saturday, June 15th. 98-101 Sincerely, Innovation Showcases . .102-105 Author Index. .107-111 ADVErtISER INDEX Douglas Melton David Scadden Leonard Zon Brock Reeve The American Society for CO-DirEctor CO-DirEctor CHair, EXECUTIVE CommittEE EXECUTIVE DirEctor Cell Biology (ASCB). 106 EMBO. .23 BD Biosciences . Inside Front Cover Karger Cells Tissues Organs. 33 BD Biosciences Travel Awards. 15 Keystone Symposia. 21 BioSpherix. Exhibits and Posters The Society for Laboratory Automation Section Tab and Screening (SLAS). 21 BioTime . .Program and Abstracts STEMCELL Technologies. Back Cover Section Tab Stemgent. .Inside Back Cover Cell Research. 41 Technology Networks. .41 eLIFE . Schedule World Conference on Regenerative Medicine. 23 Section Tab ii isscr.org/2013 isscr.org/2013 iii INTERNatioNAL SociETY for STEM CELL RESEarcH 11TH ANNUAL MEEtiNG, BostoN, MA USA SPECIAL EVENTS ISSCR SUpportErs JUNIOR EXHIBITION HALL POstER PRESENTATIONS/ We are grateful to the organizations supporting the ISSCR 11th INVEstIGATOR EVENTS Find business solutions when you meet with EXHIBIT RECEptIONS Trainees and early-career investigators: take exhibiting companies. The ISSCR 11th Annual Join us for three poster presentations, your Annual Meeting. Their generous support sustains us in our mission to advantage of these JI-focused networking and Meeting features nearly 200 leading suppliers opportunity to view and discuss the exceptional serve as the responsible voice for stem cell science worldwide. career-building sessions and vendors in the Exhibition Hall. Please work on display. Enjoy light refreshments and support ISSCR Exhibitors who help make this snacks while viewing the posters and visiting meeting possible. with exhibitors. MEET THE EXPErts CO-SPONsor NETWORKING LUNCHES REFRESHMENT BREAKS IN WEDNEsdAY, JUNE 12 THUrsdAY & FrIDAY THE EXHIBIT HAll 11:30 AM -1:00 PM EXHIBIT HAll OpEN AND POstErs WEDNESDAY, JUNE 12 OpEN FOR VIEWING The ISSCR is pleased to host the popular PM Refreshment break 3:30-4:30PM 3:30 PM – 8:30 PM “Meet the Experts”, which offers the opportunity to meet with one of 40 THUrsdAY, JUNE 13 POstER PRESENTATION I stem cell research experts over lunch. PM Refreshment break 3:00-4:00PM Supported by Harvard Stem Cell Institute Pre-registration for this event is required, FrIDAY, JUNE 14 6:30 PM – 8:30 PM but check with the registration desk to see PM Refreshment break 3:00-4:00PM Presentations for Odd-Numbered Posters ANNUAL MEEtiNG SUpportErs if there are slots still available. 6:30 PM – 7:30 PM MEET UP HUBS Presentations for Even-Numbered Posters ISSCR JUNIOR INVEstIGATOR 7:30 PM – 8:30 PM SOCIAL NIGHT Collaborate with your colleagues from around the world at the Meet Up hubs located in the THUrsdAY Exhibit Hall. Supported by BD Biosciences THUrsdAY, JUNE 13 9:00 PM – Midnight EXHIBIT HAll AND The ISSCR Junior Investigators committee NETWORKING LOUNGE POSTErs OpEN FOR VIEWING invites Junior Investigators to join us for an 11:00 AM – 4:00 PM and 6:00 PM – 8:00 PM exclusive evening of networking and fun The ISSCR Networking Lounge is the perfect supported by iPS Academia Japan, Inc.
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