Powered by TCPDF ( Case Reports 2017; 3(1)

Total Page:16

File Type:pdf, Size:1020Kb

Powered by TCPDF ( Case Reports 2017; 3(1) Powered by TCPDF (www.tcpdf.org) case reports 2017; 3(1) Editorial: CASE REPORT: ACTIVE PROGRESSIVE BASED ON CLINICAL PRACTICE LEARNING (APB-C) Arturo José Parada Baños M.D. Universidad Nacional de Colombia Faculty of Medicine Department of Obstetrics and Gynecology Bogotá, – Colombia https://doi.org/10.15446/cr.v3n1.65433 CASE REPORTS Clinical case reports date back to 1600 B. or intervention, or describe some event that C., when Egyptian papyri first described inju- is unknown (8). ries or disorders of the head and the back (1). APB-C learning is an apprentice-centered Likewise, cases reported by Hippocrates, 460 strategy that not only considers students as B.C (2), or the first uterus (3) and face trans- apprentices, but also considers any health plants (4) can be found in the literature, as well professional who progressively builds critical, as cases on the recent Zika epidemic and its autonomous, and creative thinking in an open relation to microcephaly (5). All of them have and malleable way, according to the context, greatly contributed to the evolution of medical and based on new research works. It also science during different periods, both in re- includes professionals with an analytical and search and learning processes. resolute capacity to apply this knowledge Case reports can be considered as scientific in a specific way to each new clinical case publications that represent the simplest form received and, with the potential to broaden of research in the clinical area (6); however, their knowledge and experience finding new they are the evidence of what actually happens meanings. In the context of APB-C learning, in each case. That its usefulness is purely a clinical case report represents a situation investigative is debatable. Case reports have that encourages knowledge, because it not a low profile in relation to the classification of only seeks to solve a problem, but also is, other scientific works, but their contribution to sometimes, the tip of the iceberg for new the understanding of history (1), meaningful knowledge. learning of medicine and a more humanized When the author of a clinical case report view of health care is evident (7). incorporates new knowledge into the cogni- Regardless of the current discussion on tive structure of the professionals who read the hierarchical place of case reports as a it, a meaningful learning process arises, in scientific evidence, it is clear that it has always which each reader gives a personal meaning been present in medical literature, not only to the new acquired knowledge. This way, because of its scientific value, but because relationships with their cognitive structure are it has always been a part of medical learning. established and new theoretical and method- The medicine learning process has evolved, ological elements (9) for teaching-learning moving from positivist and behaviorist the- processes of future research appear. oretical strategies to the current cognitive, One of the most relevant contributions of constructivist and socioconstructivist learning case reports, and the reason why they are still processes. These approaches have allowed an valid today, is the cognitive dynamics generat- active progressive based on clinical practice ed when meaning is given to new knowledge, (APB-C) learning, leaving passive knowledge since it could be integrated or diverge from acquisition processes behind and fostering previous knowledge about a specific topic or active, progressive, participatory and integra- pathology. This active and progressive dynamic tive processes for logical and constructive motivates new ventures in scientific research reasoning based on each clinical case. Cases or learning processes in medicine. are the essence of clinical medicine, even Case reports have been proposed as a more when they report a new disease, are gateway for undergraduate and graduate stu- rare and little known, show a new treatment dents, as well as for professors and research- CASE REPORT: ACTIVE PROGRESSIVE BASED ON CLINICAL PRACTICE LEARNING (APB-C) ers, to take their first steps into the world of REFERENCES medical literature. This position is not entirely shared by the author of this editorial, since 1. Nissen T, Wynn R. The history of the case re- case reports of all kinds have been produced port: a selective review. JRSM Open. 2014;5 throughout history, and have been submitted by (4):2054270414523410. doi: http://doi.org/b8fd. new professionals or experts and researchers 2. Abu Kasim NH, abdullah BJJ, Manikam J. of medical science who allow themselves to The current status of the case report: Terminal or be astonished by new knowledge and want viable?. Biomed Imaging Interv J. 2009;5(1):e4. doi: http://doi.org/bhpnr2. to share it. 3. Fageeh W, Raffa H, Jabbad H. Transplanta- The ability to recognize that which gener- tion of the human uterus. Int J Gynaecol Obstet. ates new meaning as learning is what allows 2002;76(3):245-51. many authors to detect a case to report and 4. Siemionow M, Papay F, Alam D, Bernard S, to share it, leaving aside the amount of ex- Djohan R, Gordon C, et al. Near-total human perience they have. If a case is significant face transplantation for a severely disfigured patient enough for an author, it might be significant in the USA. The Lancet. 2009;374(9685):203-9. for others as well. Then a literature review is doi: http://doi.org/cznvb8. initiated, although few cases out of hundreds 5. Mlakar J, Korva M, Tul N, Popović M, Pol- are actually published; what is meaningful jšak-Prijatelj M, Mraz J, et al. Zika Virus and new for an author, may not be for other Associated with Microcephaly. N Engl J Med. professionals. 2016;374:951-8. doi: http://doi.org/f8cm38. 6. Delgado-Ramírez, MB. What is the value of Historically, this type of articles have shown continuing to publish case reports? Rev Colomb a complete picture of clinical practice, which Anestesiol. 2017 [cited May 20 2017];45(S1):1- evidences the differential empathic process 3. Available from: https://goo.gl/87BT5Y. between the attending professional and his 7. Agha R, Rosin RD. Time for a new approach to patients, showing the comprehensive knowl- case reports. Int J Surg. 2010;8(5):330-2. doi: edge that is described in the narrative of the http://doi.org/b3trp6. case. Currently, this comprehensiveness in 8. Romaní-Romaní F. Reporte de caso y serie case presentation is increasingly strengthening de casos: una aproximación para el pregrado. due to the CARE guidelines (consensus-based CIMEL Ciencia e Investigación Médica Es- development of guidelines for reporting clinical tudiantil Latinoamericana. 2010 [cited May 18 cases) (10), which allow for greater scientific 2017];15(1):46-51. Visitado el 18 de mayo de validity and a comprehensive and holistic view 2017. Available from: https://goo.gl/x1cuXd. of each case presentation. 9. Ponce V. El aprendizaje significativo en la inves- tigación educativa en Jalisco. Revista Electrónica Writing and analyzing clinical case reports Sinéctica. 2004 [cited May 20 2017];24:21-9. should be part of the APB-C learning strategies Available from: https://goo.gl/. for undergraduate and graduate students, as well 10. Gagnier JJ, Kienle G, Altman DG, Moher as for practicing professionals, additionally to D, Sox H, Riley D, et al. The CARE Guideli- historical, academic and humanistic interest gen- nes: Consensus-based Clinical Case Reporting erated by the cognitive-constructivist processes Guideline Development. Glob Adv Health Med. of meaningful learning and scientific research. 2013;2(5):38-43. doi: http://doi.org/b8fs. Case Reports 2017; 3(1) https://revistas.unal.edu.co/index.php/care/article/view/58625 ENVENOMATION CAUSED BY THE BITE OF THE SNAKE BOTHRIECHIS SCHLEGELII. REPORT OF TWO CASES IN COLOMBIA Palabras clave: Bothriechis schlegelii; Mordeduras de serpientes; Coagulación sanguínea; Colombia. Keywords: Bothriechis schlegelii; Snake bites; Blood coagulation; Colombia. Mario Galofre-Ruiz, MD, MSc Tox Centro de Información de Seguridad sobre Productos Químicos CISPROQUIM Consejo Colombiano de Seguridad Bogotá D.C. – Colombia Corresponding author [email protected] Phone number.: (057)3157261026 CASE REPORTS ABSTRACT brown and black), helps it mimic its surround- ings. It has prehensile tail, and from two to four The bite by snakes of the Bothriechis genus is small superciliar scales, in the way of “eye- common in certain areas of Colombia such as lashes”. It feeds on baby birds, lizards, frogs the Coffee-growing Region. Due to their arbo- and rodents, inhabits tropical forests and corn real habits and defensiveness, these snakes and coffee crops, at altitudes ranging from 0 usually bite farmers in their upper limbs and to 2600 m; the viper reaches the highest alti- face. In Colombia, the incidence of accidents tude in Colombia (2,3). caused by these snakes has not been accu- In the regions in which it inhabits, it is also rately estimated yet because of deficiencies in known as cabeza de candado, granadilla, ví- recording this type of cases, as well as of the bora de tierra fría, víbora de pestañas, ya- ignorance on this reptile by health personnel ruma, veinticuatro, guacamaya, víbora rayo, working in its area of influence. mortiñera, colgadora and grano de oro (these This paper describes two cases of bites by B. are different names to refer to this snake in schlegelii occurred in Colombia during 2015. diverse regions of Latin America) (2,4). The first case is about a 55-year-old man who B. schlegelii extends from southern Mexi- was bitten on the left hand, and subsequent- co, throughout Central America, to the east of ly developed paresthesia and edema until the Venezuela, and in the Pacific through Costa forearm, with no other findings; the patient un- Rica, Panama, El Salvador and Ecuador (5).
Recommended publications
  • Phylogenetic Diversity, Habitat Loss and Conservation in South
    Diversity and Distributions, (Diversity Distrib.) (2014) 20, 1108–1119 BIODIVERSITY Phylogenetic diversity, habitat loss and RESEARCH conservation in South American pitvipers (Crotalinae: Bothrops and Bothrocophias) Jessica Fenker1, Leonardo G. Tedeschi1, Robert Alexander Pyron2 and Cristiano de C. Nogueira1*,† 1Departamento de Zoologia, Universidade de ABSTRACT Brasılia, 70910-9004 Brasılia, Distrito Aim To analyze impacts of habitat loss on evolutionary diversity and to test Federal, Brazil, 2Department of Biological widely used biodiversity metrics as surrogates for phylogenetic diversity, we Sciences, The George Washington University, 2023 G. St. NW, Washington, DC 20052, study spatial and taxonomic patterns of phylogenetic diversity in a wide-rang- USA ing endemic Neotropical snake lineage. Location South America and the Antilles. Methods We updated distribution maps for 41 taxa, using species distribution A Journal of Conservation Biogeography models and a revised presence-records database. We estimated evolutionary dis- tinctiveness (ED) for each taxon using recent molecular and morphological phylogenies and weighted these values with two measures of extinction risk: percentages of habitat loss and IUCN threat status. We mapped phylogenetic diversity and richness levels and compared phylogenetic distances in pitviper subsets selected via endemism, richness, threat, habitat loss, biome type and the presence in biodiversity hotspots to values obtained in randomized assemblages. Results Evolutionary distinctiveness differed according to the phylogeny used, and conservation assessment ranks varied according to the chosen proxy of extinction risk. Two of the three main areas of high phylogenetic diversity were coincident with areas of high species richness. A third area was identified only by one phylogeny and was not a richness hotspot. Faunal assemblages identified by level of endemism, habitat loss, biome type or the presence in biodiversity hotspots captured phylogenetic diversity levels no better than random assem- blages.
    [Show full text]
  • Capacidades De Gestión De Conocimiento Y Formación
    Capacidades de gestión de conocimiento y formación posgraduada para la salud en las universidades públicas de Centroamérica y República Dominicana Edmundo Torres Godoy noviembre de 2017 Capacidades de gestión de conocimiento y formación posgraduada para la salud en las universidades públicas de Centroamérica y República Dominicana © Edmundo Torres Godoy, 2017 © Organización Panamericana de la Salud, 2017 Este obra está bajo una licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional. Usted es libre para: Compartir — copiar y redistribuir el material en cualQuier medio o formato Adaptar — remezclar, transformar y crear a partir del material Bajo los siguientes términos: Atribución — Usted debe darle crédito a esta obra de manera adecuada, proporcionando un enlace a la licencia, e indicando si se han realizado cambios. Puede hacerlo en cualQuier forma razonable, pero no de forma tal que sugiera que usted o su uso tienen el apoyo del licenciante. Forma sugerida de otorgar crédito por esta obra: Torres Godoy, E. (2017). Capacidades de gestión de conocimiento y formación posgraduada para la salud en las universidades públicas de Centroamérica y República Dominicana. Organización Panamericana de la Salud. No comercial — Usted no puede hacer uso del material con fines comerciales. Compartir igual — Si usted mezcla, transforma o crea nuevo material a partir de esta obra, usted podrá distribuir su contribución siempre que utilice la misma licencia Que la obra original. No hay restricciones adicionales — Usted no puede aplicar términos legales ni medidas tecnológicas Que restrinjan legalmente a otros hacer cualQuier uso permitido por la licencia. El licenciante no puede revocar estas libertades en tanto usted siga los términos de la licencia Contenido Introducción .......................................................................................................................................
    [Show full text]
  • Envenomation Caused by the Bite of the Snake Bothriechis Schlegelii. Report of Two Cases in Colombia
    Case Reports 2017; 3(1) https://revistas.unal.edu.co/index.php/care/article/view/58625 ENVENOMATION CAUSED BY THE BITE OF THE SNAKE BOTHRIECHIS SCHLEGELII. REPORT OF TWO CASES IN COLOMBIA Palabras clave: Bothriechis schlegelii; Mordeduras de serpientes; Coagulación sanguínea; Colombia. Keywords: Bothriechis schlegelii; Snake bites; Blood coagulation; Colombia. Mario Galofre-Ruiz, MD, MSc Tox Centro de Información de Seguridad sobre Productos Químicos CISPROQUIM Consejo Colombiano de Seguridad Bogotá D.C. – Colombia Corresponding author [email protected] Phone number.: (057)3157261026 CASE REPORTS ABSTRACT brown and black), helps it mimic its surround- ings. It has prehensile tail, and from two to four The bite by snakes of the Bothriechis genus is small superciliar scales, in the way of “eye- common in certain areas of Colombia such as lashes”. It feeds on baby birds, lizards, frogs the Coffee-growing Region. Due to their arbo- and rodents, inhabits tropical forests and corn real habits and defensiveness, these snakes and coffee crops, at altitudes ranging from 0 usually bite farmers in their upper limbs and to 2600 m; the viper reaches the highest alti- face. In Colombia, the incidence of accidents tude in Colombia (2,3). caused by these snakes has not been accu- In the regions in which it inhabits, it is also rately estimated yet because of deficiencies in known as cabeza de candado, granadilla, ví- recording this type of cases, as well as of the bora de tierra fría, víbora de pestañas, ya- ignorance on this reptile by health personnel ruma, veinticuatro, guacamaya, víbora rayo, working in its area of influence.
    [Show full text]
  • Snake Venomics of Bothrops Punctatus, a Semi-Arboreal Pitviper Species from Antioquia, Colombia
    Snake venomics of Bothrops punctatus, a semi-arboreal pitviper species from Antioquia, Colombia Maritza Fernandez´ Culma1, Jaime Andres´ Pereanez˜ 1,2, Vitelbina Nu´ nez˜ Rangel1,3 and Bruno Lomonte4 1 Programa de Ofidismo/Escorpionismo, Universidad de Antioquia UdeA, Medell´ın, Colombia 2 Facultad de Qu´ımica Farmaceutica,´ Universidad de Antioquia UdeA, Medell´ın, Colombia 3 Escuela de Microbiolog´ıa, Universidad de Antioquia UdeA, Medell´ın, Colombia 4 Instituto Clodomiro Picado, Facultad de Microbiolog´ıa, Universidad de Costa Rica, San Jose,´ Costa Rica ABSTRACT Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panama,´ Colombia, and Ecuador, whose venom is poorly characterized. In the present work, the protein composition of this venom was profiled using the ‘snake venomics’ analytical strategy. Decomplexation of the crude venom by RP-HPLC and SDS-PAGE, followed by tandem mass spectrometry of tryptic digests, showed that it consists of proteins assigned to at least nine snake toxin families. Metalloproteinases are predominant in this secretion (41.5% of the total proteins), followed by C-type lectin/lectin-like proteins (16.7%), bradykinin-potentiating peptides (10.7%), phos- pholipases A2 (9.3%), serine proteinases (5.4%), disintegrins (3.8%), L-amino acid oxidases (3.1%), vascular endothelial growth factors (1.7%), and cysteine- rich secretory proteins (1.2%). Altogether, 6.6% of the proteins were not identified. In vitro, the venom exhibited proteolytic, phospholipase A2, and L-amino acid oxi- dase activities, as well as angiotensin-converting enzyme (ACE)-inhibitory activity, in agreement with the obtained proteomic profile. Cytotoxic activity on murine C2C12 myoblasts was negative, suggesting that the majority of venom phospholipases A2 Submitted 11 December 2013 likely belong to the acidic type, which often lack major toxic eVects.
    [Show full text]
  • Current Awareness in Clinical Toxicology Editors: Damian Ballam Msc and Allister Vale MD
    Current Awareness in Clinical Toxicology Editors: Damian Ballam MSc and Allister Vale MD March 2014 CURRENT AWARENESS PAPERS OF THE MONTH Patterns of presentation and clinical toxicity after reported use of alpha methyltryptamine in the United Kingdom. A report from the UK National Poisons Information Service Kamour A, James D, Spears R, Cooper G, Lupton DJ, Eddleston M, Thompson JP, Vale AJ, Thanacoody HKR, Hill SL, Thomas SHL. Clin Toxicol 2014; 52: 192-7. Objective To characterise the patterns of presentation, clinical effects and possible harms of acute toxicity following recreational use of alpha methyltryptamine (AMT) in the United Kingdom, as reported by health professionals to the National Poisons Information Service (NPIS) and to compare clinical effects with those reported after mephedrone use. Methods NPIS telephone enquiries and TOXBASE® user sessions, the NPIS online information database, related to AMT were reviewed from March 2009 to September 2013. Telephone enquiry data were compared with those for mephedrone, the recreational substance most frequently reported to the NPIS, collected over the same period. Results There were 63 telephone enquiries regarding AMT during the period of study, with no telephone enquiries in 2009 or 2010, 19 in 2011, 35 in 2012 and 9 in 2013 (up to September). Most patients were male (68%) with a median age of 20 years. The route of exposure was ingestion in 55, insufflation in 4 and unknown in 4 cases. Excluding those reporting co-exposures, clinical effects recorded more frequently in AMT (n = 55) compared with those of mephedrone (n = 488) users including acute mental health disturbances (66% vs.
    [Show full text]
  • Reptiles of Ecuador: a Resource-Rich Online Portal, with Dynamic
    Offcial journal website: Amphibian & Reptile Conservation amphibian-reptile-conservation.org 13(1) [General Section]: 209–229 (e178). Reptiles of Ecuador: a resource-rich online portal, with dynamic checklists and photographic guides 1Omar Torres-Carvajal, 2Gustavo Pazmiño-Otamendi, and 3David Salazar-Valenzuela 1,2Museo de Zoología, Escuela de Ciencias Biológicas, Pontifcia Universidad Católica del Ecuador, Avenida 12 de Octubre y Roca, Apartado 17- 01-2184, Quito, ECUADOR 3Centro de Investigación de la Biodiversidad y Cambio Climático (BioCamb) e Ingeniería en Biodiversidad y Recursos Genéticos, Facultad de Ciencias de Medio Ambiente, Universidad Tecnológica Indoamérica, Machala y Sabanilla EC170301, Quito, ECUADOR Abstract.—With 477 species of non-avian reptiles within an area of 283,561 km2, Ecuador has the highest density of reptile species richness among megadiverse countries in the world. This richness is represented by 35 species of turtles, fve crocodilians, and 437 squamates including three amphisbaenians, 197 lizards, and 237 snakes. Of these, 45 species are endemic to the Galápagos Islands and 111 are mainland endemics. The high rate of species descriptions during recent decades, along with frequent taxonomic changes, has prevented printed checklists and books from maintaining a reasonably updated record of the species of reptiles from Ecuador. Here we present Reptiles del Ecuador (http://bioweb.bio/faunaweb/reptiliaweb), a free, resource-rich online portal with updated information on Ecuadorian reptiles. This interactive portal includes encyclopedic information on all species, multimedia presentations, distribution maps, habitat suitability models, and dynamic PDF guides. We also include an updated checklist with information on distribution, endemism, and conservation status, as well as a photographic guide to the reptiles from Ecuador.
    [Show full text]
  • Taxonomic Status of Miscellaneous Neotropical Viperids, with the Description of a New Genus
    OCCASIONAL PAPERS THE MUSEUM TEXAS TECH UNIVERSITY NUMBER 153 14 AUGUST 1992 TAXONOMIC STATUS OF MISCELLANEOUS NEOTROPICAL VIPERIDS, WITH THE DESCRIPTION OF A NEW GENUS JONATHAN A. CAMPBELL AND WILLIAM w. LAMAR Despite the contributions made to crotaline systematics over the last few decades (for example, Gloyd, 1940; Klauber, 1972; Campbell and Lamar, 1989; Gloyd and Conant, 1991), the systematic status of several taxa remains questionable. We herein attempt to resolve some of these problems. Terminology follows Klauber (1972); the method of counting scales is that of Dowling (1951). We argue that recognition of certain N eotropical genera (Bothriechis and Bothriopsis) accurately reflects our knowledge of natural groups and adheres to modem systematic practice. Conversely, the evidence that the genus Bothrops as presently comprised is monophyletic is less compelling. The name Bothrops, contrary to the views of several recent authors (for example, Schatti et al., 1990, and Shatti and Kramer, 1991), is masculine in gender (Smith and Larsen, 1974; Inter­ nat. Code Zool. Nomenclature, 1985, art. 30a, ii). The variation and generic allocation of Bothrops albocarinatus Shreve ( 1934) are dis­ cussed and its distribution is redefined to include south-central Colom­ bia. We discuss the reasons for our distinction between Bothrops asper and B. atrox (Campbell and Lamar, 1989), and suggest that possibly several additional unrecognized species may be present in the asper­ atrox complex. Bothrops microphthalmus colombianus Rendahl and Vestergren (1940) is elevated to specific status. Bothrops roedingeri Mertens ( 1942) and Trigonocephalus xanthogrammus Cope (1868) are placed, respectively, in the synonymies of Bothrops pictus (Tschudi, 2 OCCASIONAL PAPERS MUSEUM TEXAS TECH UNIVERSITY 1845) and B.
    [Show full text]
  • Snake Venomics and Antivenomics of Bothrops Diporus, a Medically Important Pitviper in Northeastern Argentina
    Article Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina Carolina Gay 1,†, Libia Sanz 2, Juan J. Calvete 2,* and Davinia Pla 2,*,† Received: 17 November 2015; Accepted: 17 December 2015; Published: 25 December 2015 Academic Editor: Stephen P. Mackessy 1 Facultad de Ciencias Exactas y Naturales y Agrimensura, Universidad Nacional del Nordeste, Avenida Libertad 5470, 3400 Corrientes, Argentina; [email protected] 2 Instituto de Biomedicina de Valencia, CSIC, Jaime Roig 11, 46010 Valencia, Spain; [email protected] * Correspondence: [email protected] (J.J.C.); [email protected] (D.P.); Tel.: +34-96-339-1778 (J.J.C. & D.P.); Fax: +34-96-369-0800 (J.J.C. & D.P.) † These authors contributed equally to this work. Abstract: Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B. diporus, is widely distributed throughout the country, but principally found in the Northeast, the region with the highest rates of snakebites. The venom proteome of this medically relevant snake was unveiled using a venomic approach. It comprises toxins belonging to fourteen protein families, being dominated by PI- and PIII-SVMPs, PLA2 molecules, BPP-like peptides, L-amino acid oxidase and serine proteinases. This toxin profile largely explains the characteristic pathophysiological effects of bothropic snakebites observed in patients envenomed by B. diporus. Antivenomic analysis of the SAB antivenom (Instituto Vital Brazil) against the venom of B. diporus showed that this pentabothropic antivenom efficiently recognized all the venom proteins and exhibited poor affinity towards the small peptide (BPPs and tripeptide inhibitors of PIII-SVMPs) components of the venom.
    [Show full text]
  • Redalyc.RESÚMENES
    Journal of Pharmacy & Pharmacognosy Research E-ISSN: 0719-4250 [email protected] Asociación de Académicos de Ciencias Farmacéuticas de Antofagasta Chile RESÚMENES Journal of Pharmacy & Pharmacognosy Research, vol. 2, núm. 1, mayo, 2014, pp. sxi- s357 Asociación de Académicos de Ciencias Farmacéuticas de Antofagasta Antofagasta, Chile Disponible en: http://www.redalyc.org/articulo.oa?id=496050651001 Cómo citar el artículo Número completo Sistema de Información Científica Más información del artículo Red de Revistas Científicas de América Latina, el Caribe, España y Portugal Página de la revista en redalyc.org Proyecto académico sin fines de lucro, desarrollado bajo la iniciativa de acceso abierto © 2014 Journal of Pharmacy & Pharmacognosy Research, 2 (Suppl. 1), S1-S357 ISSN 0719-4250 http://jppres.com/jppres RESÚMENES / ABSTRACTS «LATINFARMA Habana 2013» / «LATINFARMA Havana 2013» _____________________________________ This is an open access article distributed under the terms of a Creative Commons Attribution-Non-Commercial-No Derivative Works 3.0 Unported Licence. (http://creativecommons.org/licenses/by-nc-nd/3.0/ ) which permits to copy, distribute and transmit the work, provided the original work is properly cited. You may not use this work for commercial purposes. You may not alter, transform, or build upon this work. Any of these conditions can be waived if you get permission from the copyright holder. Nothing in this license impairs or restricts the author's moral rights. Este es un artículo de Acceso Libre bajo los términos de una licencia “Creative Commons Atribucion-No Comercial-No trabajos derivados 3.0 Internacional” (http://creativecommons.org/licenses/by-nc- nd/3.0/deed.es) Usted es libre de copiar, distribuir y comunicar públicamente la obra bajo las condiciones siguientes: Reconocimiento.
    [Show full text]
  • Universidade Federal Do Ceará Faculdade De Medicina Departamento De Fisiologia E Farmacologia Pós-Graduação Em Farmacologia
    UNIVERSIDADE FEDERAL DO CEARÁ FACULDADE DE MEDICINA DEPARTAMENTO DE FISIOLOGIA E FARMACOLOGIA PÓS-GRADUAÇÃO EM FARMACOLOGIA MAYRA ALEJANDRA VELASCO REYES BIOMARCADORES PRECOCES DA INJÚRIA RENAL NO ENVENENAMENTO EXPERIMENTAL INDUZIDO PELA SERPENTE COLOMBIANA Bothrops ayerbei EM RATOS FORTALEZA-CE 2017 MAYRA ALEJANDRA VELASCO REYES BIOMARCADORES PRECOCES DA INJÚRIA RENAL NO ENVENENAMENTO EXPERIMENTAL INDUZIDO PELA SERPENTE COLOMBIANA Bothrops ayerbei EM RATOS Dissertação de Mestrado apresentada à Coordenação do Programa de Pós-Graduação em Farmacologia da Universidade Federal do Ceará como requisito para obtenção do título de Mestre em Farmacologia. Orientador: Prof°. Dr. Alexandre Havt Bindá FORTALEZA-CE 2017 Dados Internacionais de Catalogação na Publicação Universidade Federal do Ceará Biblioteca Universitária Gerada automaticamente pelo módulo Catalog, mediante os dados fornecidos pelo(a) autor(a) V537b Velasco Reyes, Mayra Alejandra. Biomarcadores precoce de injuria renal no envenenamento experimental induzido pela serpente Colombiana Bothrops ayerbei em ratos / Mayra alejandra velasco reyes. – 2017. 90 f. : il. color. Dissertação (mestrado) – Universidade Federal do Ceará, Faculdade de Medicina, Programa de Pós-Graduação em Farmacologia, Fortaleza, 2017. Orientação: Prof. Dr. Alexandre Havt Bindá . 1. Bothrops ayerbei. 2. Lesão renal aguda. 3. Biomarcadores renais. 4. Acidente ofídico. I. Título. CDD 615.1 MAYRA ALEJANDRA VELASCO REYES BIOMARCADORES PRECOCES DA INJÚRIA RENAL NO ENVENENAMENTO EXPERIMENTAL INDUZIDO PELA SERPENTE COLOMBIANA Bothrops ayerbei EM RATOS Dissertação de Mestrado apresentada à Coordenação do Programa de Pós-Graduação em Farmacologia da Universidade Federal do Ceará como requisito para obtenção do título de Mestre em Farmacologia. Aprovado em 14 de junho de 2017. BANCA EXAMINADORA ______________________________________________________ Prof. Dr. Alexandre Havt Bindá Universidade Federal do Ceará – UFC (Orientador) ________________________________________________________ Profª.
    [Show full text]
  • Universidad Nacional Mayor De San Marcos Universidad Del Perú
    Universidad Nacional Mayor de San Marcos Universidad del Perú. Decana de América Dirección General de Estudios de Posgrado Facultad de Ingeniería Geológica, Minera, Metalúrgica y Geográfica Unidad de Posgrado Estudio citogenético convencional y de genotoxicidad en Rhoadsia altipinna (Characiformes) del río Dos Bocas, El Oro, Ecuador TESIS Para optar el Grado Académico de Doctor en Ciencias Ambientales AUTOR Omar Rogerio SÁNCHEZ ROMERO ASESOR Dra. Sonia Ruthy VALLE RUBIO Lima, Perú 2019 Reconocimiento - No Comercial - Compartir Igual - Sin restricciones adicionales https://creativecommons.org/licenses/by-nc-sa/4.0/ Usted puede distribuir, remezclar, retocar, y crear a partir del documento original de modo no comercial, siempre y cuando se dé crédito al autor del documento y se licencien las nuevas creaciones bajo las mismas condiciones. No se permite aplicar términos legales o medidas tecnológicas que restrinjan legalmente a otros a hacer cualquier cosa que permita esta licencia. Referencia bibliográfica Sánchez, O. (2019). Estudio citogenético convencional y de genotoxicidad en Rhoadsia altipinna (Characiformes) del río Dos Bocas, El Oro, Ecuador. Tesis para optar grado de Doctor en Ciencias Ambientales. Unidad de Posgrado, Facultad de Ingeniería Geológica, Minera, Metalúrgica y Geográfica, Universidad Nacional Mayor de San Marcos, Lima, Perú. HOJA DE METADATOS COMPLEMENTARIOS CODIGO ORCID DEL AUTOR: https://orcid.org/0000-0003-1381- 3222 CODIGO ORCID DEL ASESOR: https://orcid.org/0000-0001-9019- 1100 DNI: 0702244674 GRUPO DE INVESTIGACIÓN: Investigación individual INSTITUCIÓN QUE FINANCIA PARCIAL O TOTALMENTE LA INVESTIGACIÓN: Universidad Técnica de Machala UBICACIÓN GEOGRÁFICA DONDE SE DESARROLLÓ LA INVESTIGACIÓN. DEBE INCLUIR LOCALIDADES Y COORDENADAS GEOGRÁFICAS: Río Dos Bocas, Sector La Cadena, Parroquia El Progreso, Cantón Pasaje, Ecuador, cuyas coordenadas son 03° 16'07.6'S; 079° 44'14.8''W .
    [Show full text]
  • VIGILANCIA DE LOS ACCIDENTES CAUSADOS POR ANIMALES PONZOÑOSOS Protocolo De Vigilancia De Los Accidentes Por Animales Ponzoñosos
    VIGILANCIA DE LOS ACCIDENTES CAUSADOS POR ANIMALES PONZOÑOSOS Protocolo de Vigilancia de los Accidentes por Animales Ponzoñosos 1. ENTRADA 1.1. DEFINICIÓN DEL EVENTO. Descripción: La vigilancia del accidente causado por animal ponzoñoso consiste en su identificación (agente), seguimiento, monitoreo y evaluación de las condiciones ambientales que constituyen riesgo para la salud colectiva, asi como el seguimiento, tratamiento, recuperación y rehabilitación del paciente accidentado. 1.2 DEFINICIONES OPERATIVAS. ACCIDENTE POR ANIMAL PONZOÑOSO. Los accidentes por animales ponzoñosos son los causados por serpientes (ofidios), arañas, abejas y alacranes (escorpiones), los cuales pueden causar alteraciones leves o graves en la salud de la víctima, inclusive su muerte, dependiendo del tipo de lesión y del sitio de exposición, así como del tamaño y especie de animal causante del evento. En Colombia y más específicamente en Antioquia la mayor gravedad y letalidad de los accidentes son los causados por serpientes y en una pequeña proporción los accidentes por alacranes, abejas y arañas. 1.2.1. Accidente ofídico. Es el ocasionado como consecuencia de la mordedura (agresión) por serpientes. En el mundo existen aproximadamente 3.000 especies de serpientes. En Colombia se encuentran aproximadamente 230 especies distribuidas en ocho familias, de esas 8 familias solo 2 se consideran venenosas: Las familias Viperidae y Elapidae y una sola especie en el mar, la especie Pelamis platurus, que se encuentra exclusivamente en el Océano Pacífico. Las Serpientes
    [Show full text]