Recombinant Mouse Bone Morphogenetic mass is 55-60&120 kDa. Protein Receptor Type IA/Activin Purity Receptor-like Kinase 3 , C-Fc-6His, Human cells Greater than 95% as determined by reducing SDS-PAGE.

Source #C520349 Storage: -20°C Package:10 μg/50 μg Human Cells.

Physical Appearance

This product is only used for scientific Sterile Filtered White lyophilized (freeze-dried) powder. research. It can not be used in medical Formulation treatment or diagnostic procedure for people or animals. It can not be used as food, cosmetics or Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150 household products. No one may manufacture, mM NaCl, pH 7.4. promise to sell, import, or use all relevant patents and Endotoxin trademarks of a product without authorization or approval in writing. If you need permission for other Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. uses, please contact us or visit our website. You must Reconstitution comply with all applicable licensing requirements on the product page when using this product. It is your Dissolve the lyophilized protein in distilled water. responsibility to read, understand and comply with all Background provisos of this kind. ALK-3 is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the protein kinase superfamily, TKL Description Ser/Thr protein kinase family and TGFB receptor subfamily. Recombinant Mouse Bone Morphogenetic Protein Receptor The BMP receptors consists of the type I receptors BMPR1A Type IA/Activin Receptor-like Kinase 3 is produced by our and BMPR1B and the type I I receptor BMPR2. Seven known Mammalian expression system and the target gene encoding type I serine/threonine kinases and five mammalian type II Gln24-Arg152 is expressed with a Fc, 6His tag at the serine/threonine kinase receptors function in TGF-beta C-terminus. superfamily signal transduction. The downstream molecules of the type I BMP receptors include the Smad (Smad1, 5 and Storage 8) proteins that are phosphorylated in a ligand-dependent Lyophilized protein should be stored at < -20°C, though stable manner, and relay the BMP signal from the receptors to target at room temperature for 3 weeks.Reconstituted protein genes in the nucleus. Type II receptors phosphorylate and solution can be storedS at 4-7angon°C for 2-7 days.Aliquots of a ctivBiate type I roeceptorts wehich auchtophosphorylate, then bind reconstituted samples are stable at < -20°C for 3 months. and activate SMAD transcriptional regulators. ALK-3 contains a GS domain and a protein kinase domain. ALK-3 is widely Usage expressed. Defects in BMPR1A gene are a cause of a This material is offered by Sangon Biotech for research, significant proportion of cases of Juvenile polyposis laboratory or further evaluation purposes. NOT FOR HUMAN syndrome (JPS). USE. Accession Molecular Weight P36895. The theoretical molecular mass is 42.2 kDa, AP molecular