2018 JSAE Annual Congress (Spring)
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Proteomics of Serum Extracellular Vesicles Identifies a Novel COPD Biomarker, Fibulin-3 from Elastic Fibres
Title: Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres Authors: Taro Koba, Yoshito Takeda*, Ryohei Narumi, Takashi Shiromizu, Yosui Nojima, Mari Ito, Muneyoshi Kuroyama, Yu Futami, Takayuki Takimoto, Takanori Matsuki, Ryuya Edahiro, Satoshi Nojima, Yoshitomo Hayama, Kiyoharu Fukushima, Haruhiko Hirata, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Mayumi Suzuki, Yuya Shirai, Teruaki Murakami, Kaori Nakanishi, Takeshi Nakatani, Yasuhiko Suga, Kotaro Miyake, Takayuki Shiroyama, Shohei Koyama, Hiroshi Kida, Takako Sasaki, Koji Ueda, Kenji Mizuguchi, Jun Adachi, Takeshi Tomonaga, Atsushi Kumanogoh Data Supplement Sample collection and approval All serum samples were collected in Osaka University Hospital and stored at -80ºC until analysis. Approval was obtained from the Osaka University Graduate School of Medicine Institutional Review Board; all patients gave written informed consent to participate in the study, and they were arrowed to fast on free will. All methods were performed in accordance with relevant guidelines and regulations. Mouse experiments were approved by the Osaka University’s Animal Care and Use Committee, and all of the animal procedures were performed following the Osaka University guidelines on animal care. Statistical analyses Statistical analyses were conducted using JMP Pro v. 14.3.0 (SAS Institute, Cary, NC, USA). Pearson’s chi-square test or Welch’s t-test was used to compare healthy controls with COPD patients. Correlations between two parameters were calculated using Spearman’s rank correlation coefficients. Differences were considered statistically significant at p < 0.05. Ward’s hierarchical cluster analysis was used to divide COPD patients into two groups by up- and down-regulated proteins. Receiver operating characteristic curves were constructed using the SRM (selected reaction monitoring) results. -
As of 15Th.April.2020) *Items Listed May Be Modified Along with the Circumstances of Supervising Organizations
ADDITIONAL ENGLISH INFORMATION OF EXCELLENT SUPERVISING ORGANIZATION (As of 15th.April.2020) *Items listed may be modified along with the circumstances of supervising organizations. In that case, we will modify the list shortly. Job Categories (Eligible when Interns shifts to No. of Person in charge Name of Organization Date of Approval Date of Expiry Accepting Country No. Name of Organization Address in English TEL HP Technical Intern Training (ii)) *Refer to Implementing TEL (in English) (Y/M/D) (Y/M/D) *Refer to Country Code Name Email Category Code Organizations* FAX ISS HOKKAIDO business 〒067-0056, 2F No.225 Mihara, Ebetsu-shi, TEL: 011-807-0491 1 ISS北海道事業協同組合 0118070491 N/A 2018/10/31 2023/10/30 CHN, VNM 1-1, 1-2, 3-21, 4-2, 4-9, 4-10, 7-6 70 佐藤(Sato) [email protected] cooperative association Hokkaido FAX: 011-807-0492 2 網走国際交流協同組合 0152462447 2018/12/10 2023/12/9 CHN 1-2, 4-2, 4-4, 4-6 7 アパレルファッション研究協同組合 3 0139551525 2018/1/22 2023/1/21 KHM 5-6 4 (事業休止中) 〒058-0204, 182-2 Erimocho Honchou, TEL: 01466-2-2211 4 えりも漁業協同組合 Erimo Fishery Cooperative 0146622211 http://www.jf-erimo.or.jp 2018/9/28 2023/9/27 IDN, VNM 2-1 5 岡道(Okamichi)(日本国内) [email protected] Horoizumi-gun, Hokkaido FAX: 01466-2-4090 〒049-2222, 2-188-1 Sawara, Mori-machi, [email protected] TEL: 01374-8-5111 5 渡島国際交流事業協同組合 N/A 0137485111 N/A 2017/11/1 2022/10/31 CHN, VNM 4-3, 4-4 18 谷垣 (TANIGAKI) Kayabe-gun, Hokkaido .jp FAX: 01374-8-5112 Okhotsk International Business 〒094-0002, 1-2-42 Masago-cho, Monbetsu-shi, 6 オホーツク国際事業協同組合 0158236686 N/A 2018/6/29 2023/6/28 CHN, THA 4-3, 4-4, 4-5 18 Association Hokkaido OKHOTSK INTERNATIONAL 〒098-1702, 91-5 Oumu, Oumu-cho, Monbetsu- [email protected]. -
Models of Time Travel
MODELS OF TIME TRAVEL A COMPARATIVE STUDY USING FILMS Guy Roland Micklethwait A thesis submitted for the degree of Doctor of Philosophy of The Australian National University July 2012 National Centre for the Public Awareness of Science ANU College of Physical and Mathematical Sciences APPENDIX I: FILMS REVIEWED Each of the following film reviews has been reduced to two pages. The first page of each of each review is objective; it includes factual information about the film and a synopsis not of the plot, but of how temporal phenomena were treated in the plot. The second page of the review is subjective; it includes the genre where I placed the film, my general comments and then a brief discussion about which model of time I felt was being used and why. It finishes with a diagrammatic representation of the timeline used in the film. Note that if a film has only one diagram, it is because the different journeys are using the same model of time in the same way. Sometimes several journeys are made. The present moment on any timeline is always taken at the start point of the first time travel journey, which is placed at the origin of the graph. The blue lines with arrows show where the time traveller’s trip began and ended. They can also be used to show how information is transmitted from one point on the timeline to another. When choosing a model of time for a particular film, I am not looking at what happened in the plot, but rather the type of timeline used in the film to describe the possible outcomes, as opposed to what happened. -
Download the Program (PDF)
ヴ ィ ボー ・ ア ニ メー シ カ ョ ワ ン イ フ イ ェ と ス エ ピ テ ッ ィ Viborg クー バ AnimAtion FestivAl ル Kawaii & epikku 25.09.2017 - 01.10.2017 summAry 目次 5 welcome to VAF 2017 6 DenmArk meets JApAn! 34 progrAmme 8 eVents Films For chilDren 40 kAwAii & epikku 8 AnD families Viborg mAngA AnD Anime museum 40 JApAnese Films 12 open workshop: origAmi 42 internAtionAl Films lecture by hAns DybkJær About 12 important ticket information origAmi 43 speciAl progrAmmes Fotorama: 13 origAmi - creAte your own VAF Dog! 44 short Films • It is only possible to order tickets for the VAF screenings via the website 15 eVents At Viborg librAry www.fotorama.dk. 46 • In order to pick up a ticket at the Fotorama ticket booth, a prior reservation Films For ADults must be made. 16 VimApp - light up Viborg! • It is only possible to pick up a reserved ticket on the actual day the movie is 46 JApAnese Films screened. 18 solAr Walk • A reserved ticket must be picked up 20 minutes before the movie starts at 50 speciAl progrAmmes the latest. If not picked up 20 minutes before the start of the movie, your 20 immersion gAme expo ticket order will be annulled. Therefore, we recommended that you arrive at 51 JApAnese short Films the movie theater in good time. 22 expAnDeD AnimAtion • There is a reservation fee of 5 kr. per order. 52 JApAnese short Film progrAmmes • If you do not wish to pay a reservation fee, report to the ticket booth 1 24 mAngA Artist bAttle hour before your desired movie starts and receive tickets (IF there are any 56 internAtionAl Films text authors available.) VAF sum up: exhibitions in Jane Lyngbye Hvid Jensen • If you wish to see a movie that is fully booked, please contact the Fotorama 25 57 Katrine P. -
… … Mushi Production
1948 1960 1961 1962 1963 1964 1965 1966 1967 1968 1969 1970 1971 1972 1973 1974 1975 1976 1977 1978 1979 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 … Mushi Production (ancien) † / 1961 – 1973 Tezuka Productions / 1968 – Group TAC † / 1968 – 2010 Satelight / 1995 – GoHands / 2008 – 8-Bit / 2008 – Diomédéa / 2005 – Sunrise / 1971 – Deen / 1975 – Studio Kuma / 1977 – Studio Matrix / 2000 – Studio Dub / 1983 – Studio Takuranke / 1987 – Studio Gazelle / 1993 – Bones / 1998 – Kinema Citrus / 2008 – Lay-Duce / 2013 – Manglobe † / 2002 – 2015 Studio Bridge / 2007 – Bandai Namco Pictures / 2015 – Madhouse / 1972 – Triangle Staff † / 1987 – 2000 Studio Palm / 1999 – A.C.G.T. / 2000 – Nomad / 2003 – Studio Chizu / 2011 – MAPPA / 2011 – Studio Uni / 1972 – Tsuchida Pro † / 1976 – 1986 Studio Hibari / 1979 – Larx Entertainment / 2006 – Project No.9 / 2009 – Lerche / 2011 – Studio Fantasia / 1983 – 2016 Chaos Project / 1995 – Studio Comet / 1986 – Nakamura Production / 1974 – Shaft / 1975 – Studio Live / 1976 – Mushi Production (nouveau) / 1977 – A.P.P.P. / 1984 – Imagin / 1992 – Kyoto Animation / 1985 – Animation Do / 2000 – Ordet / 2007 – Mushi production 1948 1960 1961 1962 1963 1964 1965 1966 1967 1968 1969 1970 1971 1972 1973 1974 1975 1976 1977 1978 1979 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 … 1948 1960 1961 1962 1963 1964 1965 1966 1967 1968 1969 1970 1971 1972 1973 1974 1975 1976 1977 1978 1979 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 … Tatsunoko Production / 1962 – Ashi Production >> Production Reed / 1975 – Studio Plum / 1996/97 (?) – Actas / 1998 – I Move (アイムーヴ) / 2000 – Kaname Prod. -
Subtype-Specific Gout Susceptibility Loci and Enrichment of Selection
Ann Rheum Dis: first published as 10.1136/annrheumdis-2019-216644 on 1 April 2020. Downloaded from Crystal arthropathies EPIDEMIOLOGICAL SCIENCE Subtype- specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome- wide meta- analyses of clinically defined gout patients Akiyoshi Nakayama,1,2 Masahiro Nakatochi ,3 Yusuke Kawamura,1,4 Ken Yamamoto,5 Hirofumi Nakaoka,6 Seiko Shimizu,1 Toshihide Higashino,1,7 Teruhide Koyama,8 Asahi Hishida,9 Kiyonori Kuriki,10 Miki Watanabe,11 Toru Shimizu,12,13 Keiko Ooyama,14 Hiroshi Ooyama,14 Mitsuo Nagase,15 Yuji Hidaka,16 Daisuke Matsui,8 Takashi Tamura,9 Takeshi Nishiyama,11 Chisato Shimanoe,17,18 Sakurako Katsuura- Kamano,19 Naoyuki Takashima,20,21 Yuya Shirai,22,23 Makoto Kawaguchi,1,24 Mikiya Takao,1,25 Ryo Sugiyama,1 Yuzo Takada,26 Takahiro Nakamura,27 Hiroshi Nakashima,28 Masashi Tsunoda,28 Inaho Danjoh,29 Atsushi Hozawa,30 Kazuyoshi Hosomichi,31 Yu Toyoda,32 Yu Kubota,32 Tappei Takada,32 Hiroshi Suzuki,32 Blanka Stiburkova,33,34 Tanya J. Major,35 Tony R. Merriman,35 Nagato Kuriyama,8 Haruo Mikami,36 Toshiro Takezaki,37 Keitaro Matsuo,38,39 Sadao Suzuki,11 Tatsuo Hosoya,40,41 Yoichiro Kamatani,42,43 Michiaki Kubo,44 Kimiyoshi Ichida,40,45 Kenji Wakai,9 Ituro Inoue,6 Yukinori Okada ,22,46 Nariyoshi Shinomiya,1 Hirotaka Matsuo,1 on behalf of Japan Gout Genomics Consortium (Japan Gout) copyright. Handling editor Josef S Smolen ABSTRact Key messages ► Additional material is Objectives Genome- wide meta- analyses of clinically published online only. To view defined gout were performed to identify subtype- please visit the journal online What is already known about this subject? (http:// dx. -
The Full 100+ Page Pdf!
2014 was a unique year for pro-wrestling, one that will undoubtedly be viewed as historically significant in years to follow. Whether it is to be reflected upon positively or negatively is not only highly subjective, but also context-specific with major occurrences transpiring across the pro-wrestling world over the last 12 months, each with its own strong, and at times far reaching, consequences. The WWE launched its much awaited Network, New Japan continued to expand, CMLL booked lucha's biggest match in well over a decade, culminating in the country's first million dollar gate, TNA teetered more precariously on the brink of death than perhaps ever before, Daniel Bryan won the WWE's top prize, Dragon Gate and DDT saw continued success before their loyal niche audiences, Alberto Del Rio and CM Punk departed the WWE with one ending up in the most unexpected of places, a developing and divergent style produced some of the best indie matches of the year, the European scene flourished, the Shield disbanded, Batista returned, Daniel Bryan relinquished his championship, and the Undertaker's streak came to an unexpected and dramatic end. These are but some of the happenings, which made 2014 the year that it was, and it is in this year-book that we look to not only recap all of these events and more, but also contemplate their relevance to the greater pro-wrestling landscape, both for 2015 and beyond. It should be stated that this year-book was inspired by the DKP Annuals that were released in 2011 and 2012, in fact, it was the absence of a 2013 annual that inspired us to produce a year-book for 2014. -
British Wrestling Dvds Classic British Wrestling
BRITISH WRESTLING DVDS WWW.BRITISHWRESTLINGDVDS.VZE.COM For Any Enquiries, Please Email Me At [email protected] ------------------------------------------------------------------------------------------------------- CLASSIC BRITISH WRESTLING Hello again, grapple fans. Good afternoon to you and welcome to the 'Classic British Wrestling' section. Kent Walton introduces classic bouts featuring classic wrestlers from all over the UK. This section has now been updated with match locations and dates. In most cases, the dates shown are air dates, rather than the dates they were taped. CLASSIC BRITISH WRESTLING VOL 1 1. Kendo Nagasaki & Blondie Barratt vs. Robbie Brookside & Steve Regal (Bedworth, 15/10/1988) 2. Brian Maxine vs. Lucky Gordon (Bedworth, 15/10/1988) 3. Big Daddy & Tom Thumb vs. Drew McDonald & Sid Cooper (Everton, 2/7/1988) 4. Mel Stuart vs. Greg Valentine (Everton, 9/7/1988) 5. Bill Pearl vs. Greg Valentine (Nottingham, 18/7/1987) 6. Catweazle vs. Ian Wilson (Catford, 11/7/1987) 7. Sid Cooper & Zoltan Boscik vs. Jeff Kerry & Pete Collins (Broxbourne, 6/6/1987) 8. Pat Patton & Greg Valentine vs. Kurt & Karl Heinz (Broxbourne, 6/6/1987) 9. Sid Cooper & Zoltan Boscik vs. Greg Valentine & Pat Patton (Broxbourne, 6/6/1987) 10. Giant Haystacks vs. Jamaica George (Adwick Le Street, 20/6/1987) 11. Terry Rudge vs. Bully Boy Muir (Dartford, 27/8/1988) 12. Big Daddy & Pat Patton vs. Rasputin & Anaconda (Dartford, 27/8/1988) 13. Greg Valentine vs. Mr X (Dartford, 3/9/1988) 14. Giant Haystacks & King Kong Kirk vs. Marty Jones & Steve Logan (Nottingham, 25/7/1987) 15. Kid McCoy vs. Blackjack Mulligan (Burnley, 16/4/1988) 16. -
Logística Profesional Nº
www.tecnipublicaciones.com Revista mensual del sector logístico Control Nº 107 - Febrero 2006 Logística Profesional Febrero 2006 Febrero / Número 107 Número EEspecialspecial ddeeFERIA LLogísticaogística Zaragoza Publicación mensual del sector logístico / ffarmacéuticaarmacéutica apuesta por EEspecialspecial LLogisExpoogisExpo y eell PPilotilot LLogísticaogística iinmobiliarianmobiliaria EEspecialspecial CCarretillasarretillas eelevadoraslevadoras eeléctricasléctricas al i Gerente de área: Carlos Azofra ([email protected]) Mercado paralelo Directora: Isabel Rodrigo. ([email protected]) Redacción: Estela Martín, Verónica Fernández, a globalización y la ampliación de fronteras traen M. Melendo, I. Rabadán y Daniel Rodrigo consigo múltiples oportunidades de negocio pero Colaboradores: Diego Ullate Ltambién problemas de competencia con mercados Diseño y maquetación: emergentes, como China o los países del Este de Europa, A. G. H. donde la mano de obra, el suelo y la maquinaria son más Fotografía: Javier Jiménez y Sergio Laguna baratos a la hora de competir. Uno de los asuntos que más DEPARTAMENTOS PROPIOS preocupa en la actualidad a los fabricantes de carretillas y en Documentación particular a su asociación, MEDEA, es el del mercado para- [email protected] Teléfono: 912 972 130 lelo, o lo que es lo mismo, la introducción de maquinaria Producción y diseño de publicidad más barata y sin las correspondientes certifi caciones de cali- Teléfono: 912 972 000 dad de la CE, especialmente las que provienen de China. Agencia de Noticias Profesionales No cabe duda de que puede ser muy fuerte la tentación www.tecnipublicaciones.com/logistica de adquirir maquinaria a un precio más barato y que supo- Directora de Publicidad: Mercedes Álvarez nen una alternativa a las marcas consolidadas porque son ([email protected]) más asequibles. -
Preliminary Results for the Year Ended 29 February 2016
11 May 2016 Vertu Motors plc (“Vertu” or “Group”) Final results for the year ended 29 February 2016 Strong aftersales performance drives record revenues and profits Vertu Motors plc, the UK automotive retailer with a network of 127 sales and aftersales outlets across the UK, announces its audited results for the year ended 29 February 2016. Year ended Year ended % Change 29 February 28 February 2016 2015 Revenue £2,423.3m £2,074.9m 16.8% Adjusted EBITDA* £35.5m £28.7m 23.7% Adjusted operating profit* £28.6m £22.7m 26.0% Adjusted profit before tax* £27.4m £22.0m 24.5% Adjusted earnings per share* 6.46p 5.15p 25.4% EBITDA £34.5m £28.0m 23.2% Operating profit £27.2m £21.7m 25.3% Profit before tax £26.0m £21.0m 23.8% Earnings per share 6.06p 4.87p 24.4% Operating cash inflow £65.8m £26.1m 152.1% Net cash £23.1m £15.7m 47.1% Net assets per share 58.0p 52.7p 10.1% Tangible net assets per share 38.3p 38.3p 0.0% Dividend per share 1.30p 1.05p 23.8% * adjusted for amortisation of intangible assets and share based payments charge. Operational Highlights Increase/(decrease) year-on-year Total Like-for-Like Group revenues 16.8% 7.3% Service revenues 13.9% 6.5% Volumes : New retail vehicles 11.0% 4.0% Motability vehicles 8.4% 1.6% Fleet new cars 0.9% (4.2%) Commercial new vehicles 32.3% 22.0% Used retail vehicles 13.0% 8.0% Since 1 March 2015, acquired 16 dealerships including Audi, Honda, Volkswagen, Mercedes-Benz, Jaguar and Land Rover Improvement in recently acquired businesses driving gross margin, revenue and profit growth Continued improvement in aftersales performance - gross margins increased to 44.8% (2015: 43.5%) Post balance sheet date raised £35m to fund future acquisitions: Board expects significant deployment in coming months Trading in March and April 2016 ahead of prior year - Board remains confident about the Group’s prospects for the current year Robert Forrester, Chief Executive of Vertu said: “We have delivered significant revenue growth, which together with tight control of costs, has resulted in record profitability. -
Springseason 2015
FRÜHLINGSSEASON 2015 Plastic Dungeon ni Deai wo Shokugeki no Owari no Motomeru no wa Re-Kan! Memories Machigatteiru Darouka Souma Seraph Doga Kobo J.C.Staff J.C.Staff Pierrot Plus Wit Studio caffeine FFF FFF Crunchyroll Vivid Ore Vampire Ninja Slayer Kekkai Sensen Denpa Kyoushi Monogatari!! Holmes from Animation Madhouse Bones studio! cucuri A-1 Pictures Trigger AoiSora (D) Vivid Kaitou DamDesuYo Viewster Nagato Yuki-chan Kyoukai no Yamada-kun to Show by Rock Punch Line no Shoushitsu Rinne 7-nin no Majo Satelight Brain’s Base Bones MAPPA Liden Films caffeine FFF orz Crunchyroll Crunchyroll (D) Gunslinger Eikoku Ikke, Houkago no Ame-iro Cocoa Kumi to Tulip Stratos Nihon wo Taberu Pleiades A-1 Pictures Brain’s Base Bones Fanworks Gainax Crunchyroll AoiSora (D) --- Viewster (D) Crunchyroll (D) 2 Mikagura Gakuen Takamiya Jewelpet Hibike! Triage X Kumikyoku Nasuno Desu Magical Change Euphonium Doga Kobo DAX Production Studio Deen Xebec Kyoto Animation Chihiro Commie Ai-dle Chyuu Crunchyroll (D) Battle Spirits Urawa no Etotama Arslan Senki Ongaku Shoujo Burning Soul Usagi-chan Encourage Films, Sanzigen, Liden Sunrise Harappa Studio Deen Shirogumi Films Crunchyroll (D) Shomentoppa Crunchyroll (D) Kaitou Peachcake (D) BAR Kiraware Aki no Kanade Yasai J.C:Staff Gathering Mori caffeine 3 TOP ANIME # Titel Bewertung 1. Shokugeki no Souma 7,26041667 2. Aki no Kanade 6,82926829 3. Ninja Slayer From Animation 6,54444444 4. Kekkai Sensen 6,40833333 5. Hibike! Euphorium 5,77205882 6. Denpa Kyoushi 5,76666667 7. Arslan Se nki 5,75000000 8. Plastic Memories 5,62765957 9. Eikoku Ikke, Nihon w o Taberu 5,56060606 10. -
Nexon to Publish “Revisions Next Stage” in Japan and Globally!
January 9, 2019 NEXON Co., Ltd. http://company.nexon.co.jp/ (Stock Code: 3659, TSE First Section) New Anime “revisions” by Goro Taniguchi, Sunao Chikaoka and Shirogumi to be Developed as a Mobile Game Nexon to Publish “revisions next stage” in Japan and Globally! TOKYO – January 9, 2019 – NEXON Co., Ltd. (3659.TO) (“Nexon”), a global leader in online games, today announced that it will undertake the Japan service and global service of “revisions next stage,” a mobile game version of the new anime “revisions,” which will start airing on January 9, 2019. This title will be developed by Nexon’s consolidated subsidiary NEXON Korea Corporation with a storyline that depicts the world after the end of its prequel anime “revisions.” The game is scheduled to launch in 2019. “revisions next stage” official website: https://mobile.nexon.co.jp/revisions 1 【Features of the anime “revisions”】 Highly unique team of creators “revisions” will be directed by Goro Taniguchi, whose Planetes (Winner of the 36th Seiun Award) and Code Geass have enchanted anime fans all over the world. Scriptwriting and series composition will be done by Makoto Fukami, who deftly brought out the contrasts between the character’s daily lives and the darkness they experienced in Psycho-Pass. Original character designs will be created by Sunao Chikaoka, who brought a soft touch to his detailed art in Wake Up, Girls! The anime production will be done by Shirogumi, who have created many moving works like The Eternal Zero and Always – Sunset on Third Street. Story One day, mundane life is suddenly disrupted.