DOCSLIB.ORG

Novo and Alexion an Investor's Dream Among Big Caps in 2010

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Novo and Alexion an Investor's Dream Among Big Caps in 2010 January 06, 2011 Novo and Alexion an investor's dream among big caps in 2010 The share price performance of Novo Nordisk and Alexion Pharmaceuticals during 2010 must have exceeded the wildest dreams of even the most bullish of their shareholders. Shares in both companies recorded big gains and closed the year at record highs as sales of key products and pipeline developments exceeded expectations. In contrast, Roche and Ipsen had a year to forget, dragged down by the major clinical setback to diabetes agent taspoglutide. Ipsen’s shares lost almost half their value and closed the year at a record low, while Roche was the worst performing big pharma stock of 2010, with a number of pipeline setbacks eroding confidence in the Swiss group’s ability to introduce new candidates to offset looming biosimilar competition to its flagship products. Meanwhile the Indian healthcare market continued its remarkable run with a number of companies trading at record highs (see tables below). Big pharma analysis Large cap ($30bn+) pharma companies: top risers and fallers in FY 2010 Share price (local currency) Market capitalisation ($bn) Rank Top 5 Risers 31-Dec-09 31-Dec-10 % change YE 2009 YE 2010 1 Novo Nordisk (DKr) 336.0 629.0 +87% 40.8 57.7 2 Novartis ($) 52.48 58.95 +12% 119.0 130.8 3 Bristol-Myers Squibb ($) 24.95 26.48 +6% 42.8 45.3 4 AstraZeneca ($) 45.55 46.19 +1% 66.1 65.1 5 Eli Lilly ($) 34.72 35.04 +1% 39.9 40.4 Top 5 Fallers 1 Roche (SFr) 170.12 137.00 -19% 144.1 122.9 2 Gilead Sciences ($) 43.27 36.24 -16% 38.9 29.4 3 Baxter International ($) 58.39 50.62 -13% 35.2 29.5 4 Abbott Laboratories ($) 53.15 47.91 -10% 82.5 74.1 5 Sanofi-Aventis (€) 52.44 47.85 -9% 99.9 87.2 To put the performance of the big pharma companies displayed above into context, US healthcare stock market indices were essentially flat over the year, European stocks made decent progress, the Japanese market struggled while the Indian market surged upwards. Stock Market Index % change in FY 2010 Dow Jones Healthcare (US) +3% S&P Pharmaceuticals (US) -3% AMEX Pharmaceutical (US) -1% Dow Jones STOXX Healthcare (EU) +6% TOPIX Pharmaceutical Index (Japan) -4% Thomson Reuters India Healthcare (India) +34% Winners Pretty much everything Novo did last year turned to gold, from sales and pipeline developments of its own products to the misfortune of others (Novo looks set to enjoy sky-high value for some time, October 28, 2010). Regulatory approval and commercial uptake of diabetes drug, Victoza, have exceeded expectations, while positive pipeline developments such as long-acting insulin, Degludec, have boosted investor confidence. Meanwhile clinical setbacks to taspoglutide and safety scares for Sanofi-Aventis’ long-acting insulin, Lantus, have played into Novo's hands. Novartis was the only other big pharma company to register decent share price gains in 2010, its US shares closed the year close to record highs. In contrast to Swiss rival Roche, Novartis’ pipeline made decent progress last year, the breakthrough moment being FDA approval for the first oral pill for MS, Gilenya. The recently completed acquisition of Alcon has also removed uncertainty and was well received (Novartis ups offer to grab Alcon growth, December 15, 2010). AstraZeneca had been enjoying a largely positive year until a number of setbacks in December wiped out prior gains; most notable was the FDA’s somewhat surprising rejection of blood-thinning agent and future blockbuster, Brilinta (Brilinta decision a lump of coal for AstraZeneca, December 17, 2010). Losers Roche’s annus horribilis ended with the withdrawal of FDA approval for Avastin as a treatment for breast cancer, a significant setting for a product which was tipped to take over Lipitor’s crown as the industry’s best- selling drug (Roche fighting Avastin's corner as support officially withdrawn in breast cancer, December 17, 2010). Baxter continues to struggle to recover from serious oversupply issues in the blood plasma market (Shares in plasma companies bleeding value over slowdown fears, April 26, 2010), while doubts about growth prospects and the patent life of Gilead’s HIV franchise continues to erode confidence, as does its failure to significantly diversify its business (Gilead hurt by faltering confidence, July 19, 2010). Sales expectations for flagship products for both companies, Baxter’s Gammagard and Gilead’s Atripla, have been significantly downgraded in the last 12 months (Advair surges as Avastin tumbles, October 15, 2010). Mid cap analysis Winners While Indian generics players dominate the mid cap winners enclosure, Alexion was the stand-out performer last year, particularly during the second half of 2010 when the stock surged 170% to close at $80. The key to Alexion's success is rare disease product, Soliris, the world’s most expensive drug with annual cost in excess of $400,000 (Alexion riding high on Soliris' potential, September 29, 2010). Lupin, Sun Pharmaceutical and Dr. Reddy's all trade close to record highs, boosted by strong growth in the Indian economy as a whole, while Perrigo's blend of OTC and branded generics continues to attract investors; shares in the Michigan group also closed the year close to record highs. Losers A number of pipeline setbacks for Ipsen, most notably to taspoglutide, suggest new chief executive, Marc de Garidel, has quite a job on his hands to try and turn around the French group's fortunes (Ipsen turnaround awaited as pipeline setbacks mount, December 16, 2010). Dainippon, Warner Chilcott and Shionogi have been ever present in the mid cap fallers this year with investors querying their strategic direction (Novo leads big pharma recovery in third quarter as Roche tumbles, October 1, 2010), while the appearance of Vertex in the fallers is quite surprising. Although Vertex had a good year in terms of reporting positive pivotal data from three phase III trials of future hepatitis C blockbuster, telaprevir, expectations of success were already sky-high which has left investors questioning how much higher the stock can go (Where now for Vertex and Lilly's regrets after hat trick of telaprevir wins, September 9, 2010). Mid cap ($2.5bn-$30bn) pharma companies: top risers and fallers in FY 2010 Market capitalisation Share price (local currency) ($bn) 31-Dec- 31-Dec- % Rank Top 5 Risers YE 2009 YE 2010 09 10 change 1 Alexion Pharmaceuticals ($) 48.82 80.55 +65% 4.3 7.3 2 Lupin (Rs) 298.06 480.45 +61% 2.9 4.8 Sun Pharmaceutical Industries 3 301.42 484.65 +61% 6.9 11.2 (Rs) 4 Perrigo ($) 39.73 63.33 +59% 3.6 5.8 5 Dr. Reddy's Laboratories (Rs) 1,143.80 1,662.55 +45% 4.2 6.3 Top 5 Fallers 1 Ipsen (€) 38.76 22.84 -41% 4.8 2.7 Dainippon Sumitomo Pharma 2 1,181 738 -38% 5.2 3.6 (¥) 3 Warner Chilcott ($) 28.47 22.56 -21% 7.2 5.7 4 Shionogi (¥) 2,010 1,603 -20% 7.4 6.9 5 Vertex Pharmaceuticals ($) 42.85 35.03 -18% 8.6 7.1 More from Evaluate Vantage Evaluate HQ 44-(0)20-7377-0800 Evaluate Americas +1-617-573-9450 Evaluate APAC +81-(0)80-1164-4754 © Copyright 2021 Evaluate Ltd..
Load more

Recommended publications
  • Amgen 2008 Annual Report and Financial Summary Pioneering Science Delivers Vital Medicines
    Amgen 2008 Annual Report and Financial Summary Pioneering science delivers vital medicines About Amgen Products Amgen discovers, develops, manufactures Aranesp® (darbepoetin alfa) and delivers innovative human therapeutics. ® A biotechnology pioneer since 1980, Amgen Enbrel (etanercept) was one of the fi rst companies to realize ® the new science’s promise by bringing EPOGEN (Epoetin alfa) safe and effective medicines from the lab Neulasta® (pegfi lgrastim) to the manufacturing plant to patients. NEUPOGEN® (Filgrastim) Amgen therapeutics have changed the practice of medicine, helping millions of Nplate® (romiplostim) people around the world in the fi ght against ® cancer, kidney disease, rheumatoid Sensipar (cinacalcet) arthritis and other serious illnesses, and so Vectibix® (panitumumab) far, more than 15 million patients worldwide have been treated with Amgen products. With a broad and deep pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives. 0405 06 07 08 0405 06 07 08 0405 06 07 08 0405 06 07 08 Total revenues “Adjusted” earnings Cash fl ow from “Adjusted” research and ($ in millions) per share (EPS)* operations development (R&D) expenses* (Diluted) ($ in millions) ($ in millions) 2008 $15,003 2008 $4.55 2008 $5,988 2008 $2,910 2007 14,771 2007 4.29 2007 5,401 2007 3,064 2006 14,268 2006 3.90 2006 5,389 2006 3,191 2005 12,430 2005 3.20 2005 4,911 2005 2,302 2004 10,550 2004 2.40 2004 3,697 2004 1,996 * “ Adjusted” EPS and “adjusted” R&D expenses are non-GAAP fi nancial measures. See page 8 for reconciliations of these non-GAAP fi nancial measures to U.S.
    [Show full text]
  • Large Cap Value Fund Q3 Portfolio Holdings
    Putnam Equity Income Fund The fund's portfolio 8/31/20 (Unaudited) COMMON STOCKS (95.5%)(a) Shares Value Aerospace and defense (3.0%) Northrop Grumman Corp. 763,179 $261,472,757 Raytheon Technologies Corp. 1,931,815 117,840,715 379,313,472 Airlines (1.0%) Southwest Airlines Co. 3,596,011 135,138,093 135,138,093 Auto components (0.8%) Delphi Automotive PLC 1,165,950 100,411,614 100,411,614 Automobiles (0.7%) General Motors Co. 2,932,830 86,899,753 86,899,753 Banks (9.9%) Bank of America Corp. 13,888,550 357,491,277 Citigroup, Inc. 6,615,251 338,171,631 JPMorgan Chase & Co. 3,413,635 342,012,091 KeyCorp 3,945,705 48,611,086 PNC Financial Services Group, Inc. (The) 1,279,414 142,270,837 1,228,556,922 Beverages (2.5%) Keurig Dr Pepper, Inc.(S) 3,097,349 92,393,921 Molson Coors Beverage Co. Class B(S) 1,663,844 62,627,088 PepsiCo, Inc. 1,123,779 157,396,487 312,417,496 Biotechnology (4.5%) AbbVie, Inc. 2,005,931 192,108,012 Amgen, Inc. 804,202 203,720,451 Regeneron Pharmaceuticals, Inc.(NON) 262,080 162,471,254 558,299,717 Building products (2.3%) Fortune Brands Home & Security, Inc. 1,681,051 141,342,768 Johnson Controls International PLC 3,432,811 139,818,392 281,161,160 Capital markets (3.5%) Apollo Global Management, Inc. 2,289,153 107,292,601 Charles Schwab Corp. (The) 2,516,793 89,421,655 Goldman Sachs Group, Inc.
    [Show full text]
  • Sigma Spectrum Operator's Manual
    spectrum Operator’s Manual 35700BAX & 35700ABB Generation 2 Operating System Pump Operating Software v6.05 For Use with MDL Editor v6.2.4 SIGMA, LLC 711 Park Avenue Medina, New York 14103 v 800 356 3454 f 585 798 3909 www.sigmapumps.com Manual 41018- 6.05/6.2.4 Revision D II Pump Operating Software v6.05 For Use With MDL Editor v6.2.4 ©2011 Copyright SIGMA, LLC 711 Park Avenue Medina, New York 14103 v 800 356 3454 f 585 798 3909 www.sigmapumps.com III Manual 41018- 6.05/6.2.4 Revision D IV Pump Operating Software v6.05 For Use With MDL Editor v6.2.4 TABLE OF CONTENTS Introduction and Safety . 1 Intended Device Use . 1 Related Documents . 1 Regulatory Information . 1 Contacting SIGMA Technical Support . 1 Conventions . 2 Summary of Warnings and Cautions . 2 System Components . 11 Spectrum Pump Illustrations . 12 Hardware Labeling . 13 Battery Compatibility . 14 Setting Up the Pump . 15 Unpack the Pump . 15 AC Power Adaptor . 16 Cleaning the Power Adaptor . 16 Connecting the Power Adaptor . 16 Removing the Power Adaptor . 17 Charging the Battery . 17 Configuring User Options . 18 User Options . 18 Operational Overview . 21 Starting a New Infusion Using the Dose Error Reduction System (DERS) . 24 Starting a New Infusion using the BASIC Mode . 25 Secondary Infusions . 26 Preparing the Pump and IV Sets . 27 Loading an IV Set . 28 Unloading an IV Set . 30 Preparing the Pump for a Secondary Infusion . 30 Programming the Pump . 31 Infusion Programming Modes: . 32 Keys Used to Program and Operate the Pump .
    [Show full text]
  • PFIZER INC. (Exact Name of Registrant As Specified in Its Charter)
    UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2015 o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 1-3619 PFIZER INC. (Exact name of registrant as specified in its charter) Delaware 13-5315170 (State or other jurisdiction of incorporation or organization) (I.R.S. Employer Identification Number) 235 East 42nd Street New York, New York 10017-5755 (Address of principal executive offices) (Zip Code) (212) 733-2323 (Registrant’s telephone number, including area code) Securities registered pursuant to Section 12(b) of the Act: Title of each class Name of each exchange on which registered Common Stock, $.05 par value New York Stock Exchange Securities registered pursuant to Section 12(g) of the Act: None Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes x No o Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes o No x Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.
    [Show full text]
  • Ligand's Captisol Technology Plays Key Role in the Manufacture Of
    October 23, 2020 Ligand’s Captisol Technology Plays Key Role in the Manufacture of Gilead’s Veklury, the First FDA-Approved COVID-19 Treatment SAN DIEGO--(BUSINESS WIRE)-- Ligand Pharmaceuticals Incorporated (NASDAQ: LGND) today highlighted the company’s role in the manufacturing of Veklury® (remdesivir), Gilead Sciences’ antiviral drug for the treatment of patients with COVID-19 requiring hospitalization. Veklury is formulated with Ligand’s Captisol® technology. Approved yesterday by the U.S. Food and Drug Administration, Veklury is the first and only approved COVID-19 treatment in the United States. The drug is now widely available in hospitals across the country, following Gilead’s early investments to rapidly expand manufacturing capacity to increase supply. “We congratulate Gilead on achieving this regulatory milestone,” said John Higgins, Chief Executive Officer of Ligand. “Veklury is an important medicine that has already played a vital role in the treatment of many patients with COVID-19 worldwide. In early January Gilead contacted Ligand requesting urgent shipments of Captisol. Over the following weeks and months, the Captisol volume requirements and supply needs expanded significantly, and Ligand has been there to support Gilead in their effort to manufacture millions of treatment courses. While the progression of the pandemic was and still is unknown, Ligand made the strategic and ethical decision to invest significantly in scale-up to ensure we had sufficient capacity to meet the Captisol supply needs for Gilead and members of its international manufacturing consortium. It has been an intense nine months executing on these efforts. We are proud of our contribution to this first and only U.S.-approved treatment for COVID- 19, and we are equally proud of our ability to execute so efficiently and smoothly to answer the call.” Higgins continued, “As the number of people with COVID-19 continues to increase in most states and many countries around the world, we believe Ligand is well positioned to meet higher levels of demand for Captisol.
    [Show full text]
  • Companies with Matching Gift Programs
    Companies with Matching Gift Programs Many companies encourage charitable giving by matching gifts made by their employees. As a 501(c)(3) non-profit organization, CHCA is eligible for matching gifts. Below is a list of companies that have matching gift programs. Even if a company is not listed, they may still have a matching gift program. In addition, not all companies match PK-12 schools. To find out if your company matches gifts made to CHCA, please contact your HR representative. If you need additional assistance, please e-mail Paige Tomlin at [email protected]. A AK Steel 3Com Corporation Albemarle Corp. 3M Company Alco Standard AlliedSignal Inc. Alexander and Baldwin Inc. Allstate Alexander Hamilton Life Abacus Capital Investments Alexander Haas Martin and Partners Abbott Laboratories Al Neyer Altera Corp. Contributions Allegro Microsystems Inc. Accenture Alliance Bernstein Access Fund Alliance Capital Management L.P. ACE INA Foundation Alliance Coal LLC Adams Harkness and Hill Inc. Alliant Techsystems Altria Group Allegiance Corp. and Baxter International Adaptec Foundation Allendale Insurance Foundation AMBAC Indemnity American Natl Bank & Trust ADC Telecommunications American Intl Group, Inc. AMD Corporate Giving American Standard Found Adobe Systems Inc. Amgen Inc. ADP Foundation AMN Healthcare Services American Express Co. AmSouth BanCorp. A & E Television Networks American Stock Exchange AEGON TRANSAMERICA Ameriprise Financial AEP Ameritech Corp. AES Corporation AMETEK / Sealtron A.E. Staley Manufacturing Co. AMSTED Industries Inc. American Fidelity Corp. Amylin Pharmaceuticals Aetna Foundation, Inc. Anadarko Petroleum Corp. American General Corp. Analytics Operations Engineering AG Communications Systems Analog Devices Inc. American Honda Motor Co. Avon Products Foundation, Inc.
    [Show full text]
  • For Immediate Release
    FOR IMMEDIATE RELEASE Media Contact Steve Brett, (224) 948-5353 [email protected] Investor Contact Clare Trachtman, (224) 948-3020 BAXTER REPORTS FIRST-QUARTER 2021 RESULTS • First-quarter revenue of $2.9 billion increased 5% on a reported basis and 1% on both a constant currency and operational basis1 • First-quarter U.S. GAAP earnings per share (EPS) of $0.58 declined 9%; Adjusted EPS of $0.76 declined 7% • Baxter expects full-year 2021 sales growth of 8% to 9% on a reported basis, 5% to 6% on a constant currency basis and 4% to 5% on an operational basis • Baxter expects full-year U.S. GAAP EPS of $2.85 to $2.93 and adjusted EPS of $3.47 to $3.55 DEERFIELD, Ill., APRIL 29, 2021 – Baxter International Inc. (NYSE:BAX), a leading global medical products company, today reported results for the first quarter of 2021. “Baxter’s medically essential products are fundamental to healthcare, and many have proven pivotal in the fight against COVID-19,” said José (Joe) E. Almeida, chairman, president and chief executive officer. “Our life-sustaining portfolio, broad geographic reach and the ongoing momentum of our business transformation are all keys to our resilience. We are well positioned to strengthen our impact in the year ahead, fueled by our innovative product pipeline, relentless focus on execution, and capital deployment opportunities to benefit patients, customers and investors.” First-Quarter Financial Results Worldwide sales in the first quarter totaled approximately $2.9 billion, an increase of 5% on a reported basis and 1% on both a constant currency and operational basis.
    [Show full text]
  • Chicago's Competition
    STATE SURVEY: ILLINOIS James Mutchnik Robert Bloch Tom Frederick Amy Manning Chicago’s competition bar Over the past few years, Chicago’s federal court has become one of the busiest antitrust litigation forums in the country. Ron Knox meets the Windy City’s leading competition lawyers HANDFUL of decisions handed down recently by the Seventh says Kirkland & Ellis partner James Mutchnik PC, who is nominated Circuit court of appeals have fuelled the perception that to The International Who’s Who of Competition Lawyers and Chicago is a fitting home for courtroom warriors embroiled Economists. in some of the largest and most complex antitrust cases in The changes do not end there. Two years ago, Kirkland & Ellis Athe country. Practitioners here predict a future where even more began transitioning from separate (albeit good) offices and antitrust plaintiffs’ lawyers set up shop or expand their practices, putting teams around the country to a truly integrated national practice. more cases before Chicago courts and calling the prominent defence Before, Mutchnik says, the practice was a vertical one for the most bar into action. part. “We’re beyond that now,” he says. The firm has now identified Of course, Chicago firms still handle their share of mergers and and connected a core team of litigators from each office to help government investigations. But many antitrust practices here rank boost its private antitrust litigation ability. Partner Daniel Laytin themselves and their competitors by the number of multi-district leads the way in Chicago and says that with the firm’s client base litigations (MDLs) they’re involved in.
    [Show full text]
  • Schedule of Investments Health Care Fund
    SCHEDULE OF INVESTMENTS December 31, 2020 HEALTH CARE FUND SHARES VALUE SHARES VALUE COMMON STOCKS† - 99.5% Dentsply Sirona, Inc. 2,228 $ 116,658 Repligen Corp.* 571 109,421 PHARMACEUTICALS - 31.9% Penumbra, Inc.* 527 92,225 Johnson & Johnson 4,485 $ 705,849 Quidel Corp.* 503 90,364 Merck & Company, Inc. 6,248 511,086 Tandem Diabetes Care, Inc.* 941 90,035 Pfizer, Inc. 13,634 501,868 Hill-Rom Holdings, Inc. 891 87,291 AbbVie, Inc. 4,543 486,782 Haemonetics Corp.* 710 84,312 Bristol-Myers Squibb Co. 6,569 407,475 Nevro Corp.* 459 79,453 Eli Lilly & Co. 2,391 403,696 iRhythm Technologies, Inc.* 332 78,754 CVS Health Corp. 4,915 335,695 Cigna Corp. 1,514 315,185 Total Healthcare-Products 6,434,517 Zoetis, Inc. 1,844 305,182 BIOTECHNOLOGY - 16.9% Becton Dickinson and Co. 1,171 293,008 Amgen, Inc. 1,729 397,532 DexCom, Inc.* 560 207,043 Gilead Sciences, Inc. 5,148 299,923 McKesson Corp. 1,078 187,486 Vertex Pharmaceuticals, Inc.* 1,124 265,646 Viatris, Inc.* 9,039 169,391 Illumina, Inc.* 684 253,080 AstraZeneca plc ADR 3,193 159,618 Regeneron Pharmaceuticals, Inc.* 507 244,937 AmerisourceBergen Corp. — Class A 1,609 157,296 Biogen, Inc.* 849 207,886 Jazz Pharmaceuticals plc* 945 155,972 Moderna, Inc.* 1,869 195,254 ,1 Canopy Growth Corp.* 6,273 154,567 Alexion Pharmaceuticals, Inc.* 1,124 175,614 Horizon Therapeutics plc* 1,986 145,276 Seagen, Inc.* 995 174,264 Novartis AG ADR 1,512 142,778 Exact Sciences Corp.* 1,170 155,013 Cardinal Health, Inc.
    [Show full text]
  • Baxter Annual Report 2002
    living proof Baxter International Inc. Annual Report 2002 Baxter’s vision is to be the global leader in providing critical therapies to people with life- threatening conditions. In pursuit of this goal, Baxter is continuing a rich tradition of innovation, having pioneered products and therapies that have saved and enhanced the lives of millions. The patients featured in this report are living proof of how Baxter is making a meaningful difference in patients’ lives. These efforts also are accelerating Baxter’s growth, positioning the company for continued success now and into the future. Dear Fellow Shareholders: The theme of this year’s annual report – living proof –reflects how Baxter is making an important difference in the lives of people with complex medical conditions such as hemo- philia, kidney disease and cancer, while also contributing to better public health with new vaccines and technologies that improve the safety of the blood supply. The patients profiled in this report are examples of the millions of people around the world who depend on Baxter products and services to lead productive and satisfying lives. Our entire Baxter team is very privileged to have a positive impact on the lives of so many people. It is the classic philosophy of our Chairman Emeritus William B. Graham, who stated the importance of “doing well by doing good.” I believe this summarizes the essence of what we do. Our 55,000 team members in more than 100 countries are dedicated to advancing the best in health care, working together to develop medical innovations that help health-care profes- sionals enhance the effectiveness and delivery of therapies to patients worldwide.
    [Show full text]
  • Schedule of Investments Health Care Fund
    SCHEDULE OF INVESTMENTS December 31, 2019 HEALTH CARE FUND SHARES VALUE SHARES VALUE COMMON STOCKS† - 99.6% Insulet Corp.* 657 $ 112,478 Henry Schein, Inc.* 1,575 105,084 PHARMACEUTICALS - 34.7% Masimo Corp.* 636 100,526 Johnson & Johnson 4,586 $ 668,960 Abiomed, Inc.* 572 97,577 Merck & Company, Inc. 5,761 523,963 Repligen Corp.* 819 75,758 Pfizer, Inc. 12,923 506,323 NuVasive, Inc.* 897 69,374 Bristol-Myers Squibb Co. 6,640 426,222 Tandem Diabetes Care, Inc.* 1,101 65,631 AbbVie, Inc. 4,443 393,383 Eli Lilly & Co. 2,925 384,433 Total Healthcare-Products 5,147,377 CVS Health Corp. 4,523 336,014 BIOTECHNOLOGY - 19.5% Cigna Corp. 1,486 303,872 Amgen, Inc. 1,701 410,060 Becton Dickinson and Co. 1,090 296,447 Gilead Sciences, Inc. 4,793 311,449 Zoetis, Inc. 2,074 274,494 Vertex Pharmaceuticals, Inc.* 1,184 259,237 Allergan plc 1,431 273,564 Biogen, Inc.* 844 250,440 McKesson Corp. 1,258 174,007 Illumina, Inc.* 729 241,838 DexCom, Inc.* 710 155,305 Regeneron Pharmaceuticals, Inc.* 589 221,158 AmerisourceBergen Corp. — Class A 1,699 144,449 Alexion Pharmaceuticals, Inc.* 1,516 163,955 Cardinal Health, Inc. 2,621 132,570 Seattle Genetics, Inc.* 1,314 150,138 AstraZeneca plc ADR 2,516 125,448 Incyte Corp.* 1,669 145,737 Jazz Pharmaceuticals plc* 818 122,111 BioMarin Pharmaceutical, Inc.* 1,575 133,166 Novartis AG ADR 1,243 117,700 Amarin Corporation plc ADR*,1 5,809 124,545 ,1 Canopy Growth Corp.* 5,456 115,067 Exact Sciences Corp.* 1,307 120,871 Elanco Animal Health, Inc.* 3,845 113,235 Alnylam Pharmaceuticals, Inc.* 1,044 120,238 GlaxoSmithKline
    [Show full text]
  • D:\Webstuff\0210171 Baxter Wyeth Consent Agreement
    UNITED STATES OF AMERICA BEFORE FEDERAL TRADE COMMISSION __________________________________________ ) In the Matter of ) ) BAXTER INTERNATIONAL INC., ) a corporation; ) ) File No. 021-0171 and ) ) WYETH, ) a corporation. ) ) __________________________________________) AGREEMENT CONTAINING CONSENT ORDERS The Federal Trade Commission (“Commission”), having initiated an investigation of the proposed acquisition of certain assets of Wyeth by Baxter International Inc. (“Baxter”), and it now appearing that Wyeth and Baxter hereinafter sometimes referred to as “Proposed Respondents,” are willing to enter into this Agreement Containing Consent Orders (“Consent Agreement”) to divest certain assets and providing for other relief: IT IS HEREBY AGREED by and between Proposed Respondents, by their duly authorized officers and attorneys, and counsel for the Commission that: 1. Proposed Respondent Baxter is a corporation organized, existing, and doing business under and by virtue of the laws of the state of Delaware, with its office and principal place of business located at One Baxter Parkway, Deerfield, Illinois 60015. 2. Proposed Respondent Wyeth is a corporation organized, existing, and doing business under and by virtue of the laws of the state of Delaware, with its office and principal place of business located at Five Giralda Farms, Madison, New Jersey 07940. 3. Proposed Respondents admit all the jurisdictional facts set forth in the draft of Complaint here attached. 4. Proposed Respondents waive: (a) any further procedural steps; (b) the requirement that the Commission’s Order to Maintain Assets and Decision and Order, both of which are attached hereto and made a part hereof, contain a statement of findings of fact and conclusions of law; (c) all rights to seek judicial review or to otherwise challenge or contest the validity of the Order to Maintain Assets or the Decision and Order entered pursuant to this Consent Agreement; and (d) any claim under the Equal Access to Justice Act.
    [Show full text]