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Annual Report 2018 Annual Report 2018 YEARS Annual Report 2018 Greeting 2 About us 4 The year 2018 in figures 6 The Pasqual Maragall Foundation celebrates 10 years fighting against Alzheimer’s 8 The research: the Barcelonaβeta Brain Research Center (BBRC) 1 0 Alpha Study 11 Alzheimer’s Prevention Program 1 2 Clinical Research Group, Biomarkers and Risk Factors 12 Neuroimaging Research Group 13 Edition Pasqual Maragall Fundation Research projects Barcelonaßeta Brain Research Center Foundation 14 Wellington, 30 08005 Barcelona International collaborations 1 7 +34 933 160 990 [email protected] Clinical trials 1 9 www.fpmaragall.org Principal scientific publications 20 Date of publication May 2019 Conferences and talks 22 Social area: therapeutic groups 24 Fundraising and social support 25 Dissemination 30 Origin and destination of resources 34 Partners 36 Total or partial reproduction of this publication, treatment in any form or by any means, electronic, mechanical, photocopying, recording, or other methods, or its Boards 38 loan, rent or any other form of cession of use of the copy is not allowed without prior written permission of the copyright holder. 2 Greeting Greeting “I want to help defeat Alzheimer’s. It Barcelona Brain Research Center (BBRC), since this center, with its cutti ng-edge is not easy or simple, but nowhere is more than 2,500 visits in the diff erent infrastructures and a concentrati on of it writt en that it is invincible.”These research projects and clinical trials that indisputable talent, also confi rms, ten were the words pronounced by the we have underway. This involves more years later, the commitment achieved. former mayor of Barcelona and former than 1,200 cogniti on sessions, more than president of the Generalitat of Catalonia 1,000 nursing sessions, more than 21,000 With wishes fulfi lled and also dreams on October 20th, 2007, when he processed samples, more than 230 to be realized, we conti nue advancing announced that he had been diagnosed lumbar punctures and more than 1,000 thanks to the support of many people with an Alzheimer’s onset. In that press MRI acquisiti ons. and enti ti es that have accompanied conference he also claimed: “I want us throughout this ti me in the to help to advance, as far as I can, the To this intense acti vity we must add the materializati on of that vision. We refer to research on this disease.” This public start, this year, of the Clinical Research enti ti es such as “la Caixa”, the support of commitment materialized in April 2008 Unit in the Preventi on of Dementi a, a which has made it possible to transform with the start-up of the Pasqual Maragall new pioneering research project that what should be a study of 400 people With wishes fulfi lled and Foundati on. studies the risk, and its biological bases, in the current cohort of almost 3,000 also dreams to be realized, of developing dementi a during fi ve people. And to all the enti ti es of our So in 2018 we have commemorated our years. We have also launched the Bio Board of Patronage, which, with their we continue advancing 10th anniversary. And we have done it by Alfa research project, focused on blood fi nancial contributi ons, make our project taking stock and refl ecti ng on the road factors associated with aging and brain viable. And to the more than 24,000 thanks to the support of traveled. It has been a decade of eff ort, rejuvenati on. members who make up the current social many people and entities growth and great moments. All this has base that drives us every day to keep given us more strength and experience, At an internati onal level, we conti nue to improving, since this project belongs to that have accompanied us and has reaffi rmed us in the convicti on consolidate alliances and collaborati ons, each one of them and a hope in which throughout this time in the that, if we conti nue advancing, we will such as the EPAD European project, in all, researchers, workers, volunteers, end this disease. which in 2018 the BBRC was the center collaborators and enti ti es, we believe. materialization of that vision with the most registered parti cipants Jordi Camí Achievements as the excepti onal from all over Europe and AMYPAD, a We close the fi rst decade of our founding General Director of response, in 2012, of more than 6,000 European collaborati on to improve the history and open a new stage with an Thank you for these 10 years! the Pasqual Maragall Foundati on. people, who volunteered for our call knowledge and diagnosis of Alzheimer’s eye on the future, in which, we are sure, to launch the Alfa Study. About 3,000 disease using the PET imaging technique we will have many new achievements to of those people represent now one of (positron emission tomography). celebrate together. the largest study cohorts in Alzheimer’s preventi on in the world. And thanks to This excellent and ti reless task is carried Thank you for these 10 years! their generosity and predispositi on, for out by more than 50 researchers and example, only in 2018, we have been able professionals of the BBRC. And here Jordi Camí to carry out from our research center, the is another reason for celebrati on, Director 2 3 Pasqual Maragall Foundation _ Barcelonaβeta About us Brain Research Center ALZHEIMER’S TODAY Every day thousands of new cases The Pasqual Maragall Foundation of dementia are diagnosed in and the Barcelonaβeta Brain Research the world, whose main cause is Center work tirelessly to fi nd a Alzheimer’s It is estimated that in solution We are convinced that the world there are about 50 million research is the only way out And cases of dementia1 and only in Spain prevention is the key to stopping the about 800,000 cases 2 advance of this epidemic: Every 3 seconds a new case The Pasqual Maragall The Barcelonaβeta of dementi a is diagnosed in the world. IF WE WERE ABLE TO Foundation Brain Research Center DELAY ONLY FIVE YEARS THE START OF With the vision of achieving a future The Barcelonaβeta Brain Research Center THE ALZHEIMER’S, THE without Alzheimer’s, the Pasqual Maragall (BBRC) is a research center dedicated to 1 Of every 10 people Foundati on promotes and develops the preventi on of Alzheimer’s disease and over 65 years old NUMBER OF SICK PEOPLE the ulti mate biomedical research to the study of cogniti ve functi ons aff ected has alzheimer’s. COULD BE REDUCED TO contribute to the decisive soluti ons to this in healthy and pathological aging. It was 3 disease. created in 2012 by the Pasqual Maragall ALMOST HALF Foundati on, with the support of the The objecti ve is to prevent its onset, Pompeu Fabra University. 2050 determining what factors aff ect its start and development, designing interventi ons The mission of the BBRC is to provide to act before it is too late and expanding innovati ve soluti ons to decipher ONE OF EVERY knowledge about the cogniti ve functi ons and prevent biological changes and TODAY Transparency THREE CASES OF and good practice aff ected in aging. cogniti ve dysfuncti on associated with neurodegenerati ve diseases. Its researchers DEMENTIA COULD BE The Pasqual Maragall The Foundati on also works to generate carry out research projects of neuroimaging Foundati on and the PREVENTED MAKING A social awareness about the eff ects of this and primary and secondary Alzheimer’s If an eff ecti ve cure is not found, by 2050 Barcelonaβeta Brain 4 Research Center have disease and the importance of scienti fi c preventi on, and acti vely parti cipate in the number of cases will have tripled. CHANGE OF LIFE HABITS a code of good practi ces research to fi nd soluti ons. studies and internati onal work groups in transparency and focused on the preventi on of the disease. accountability and a code While these soluti ons do not arrive, the of good scienti fi c practi. ce Foundati on is also committ ed to improve In 2018 the Catalan Associati on the quality of life of aff ected people and 1 Data of the World Health Organizati on of Research Enti ti es (ACER) unanimously (WHO). their caregivers . agreed to the incorporati on of the BBRC. 2 Data of the World Alzheimer Report. 3 Data of the Alzheimer’s Associati on Treatment Report: Changing the Trajectory of Alzheimer’s Disease: How a Treatment by 2025 Saves Lives and Dollars. 4 Norton et al. “Potenti al for primary preventi on of Alzheimer’s disease: an analysis of populati on-based data”. Lancet Neurol. 2014 Aug (13);8:788-94. 4 5 L’any en xifres The year 2018 in fi gures* * Provisional closure of 2018 Aggregated data from the Pasqual Maragall Foundation and the Barcelonaβeta Brain Research Center The two entities are subject to an external 2018 annual accounts audit Budget 24,508 1,228 48,733 €8,622,166 Members Cognition sessions Social media followers €4,154,639 121 1,050 Pasqual Maragall Foundation Staff at headquarters Magnetic resonance 1,430 acquisitions Appearances in the media €4,467,527 939 Barcelonaβeta Participants visited 162 Brain Research Center Caregivers participating 113 in therapeutic groups Solidarity actions 6 7 10 Years fi ghting against alzheimer’s The Pasqual Maragall Foundation celebrates 10 years fi ghting against Alzheimer’s Memories Presentation 10th anniversary gala in Barcelona To commemorate the 10th anniversary, On November 14th, the Pasqual and on the occasion of World On September 20th, the book Recuerdos Maragall Foundati on celebrated its 10th Alzheimer’s Day, on September 21st, the was presented at an event organized anniversary in the company of volunteers Foundati on asked 40 friends of Pasqual by the RBA Foundati on and att ended who parti cipate in its research projects, Maragall to share an unforgett able by more than 800 people.
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