BMC Genomics BioMed Central Research article Open Access Differential gene expression in femoral bone from red junglefowl and domestic chicken, differing for bone phenotypic traits Carl-Johan Rubin1, Johan Lindberg2, Carolyn Fitzsimmons3, Peter Savolainen2, Per Jensen4, Joakim Lundeberg2, Leif Andersson3,5 and Andreas Kindmark*1 Address: 1Department of Medical Sciences, Uppsala University, Sweden, 2Department of Gene Technology, School of Biotechnology, Royal Institute of Technology, Stockholm, Sweden, 3Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden, 4IFM Biology, Linköping University, SE-585 83, Linköping, Sweden and 5Department of Medical Biochemistry and Microbiology, Uppsala University, Box 597, SE-75124 Uppsala, Sweden Email: Carl-Johan Rubin -
[email protected]; Johan Lindberg -
[email protected]; Carolyn Fitzsimmons -
[email protected]; Peter Savolainen -
[email protected]; Per Jensen -
[email protected]; Joakim Lundeberg -
[email protected]; Leif Andersson -
[email protected]; Andreas Kindmark* -
[email protected] * Corresponding author Published: 2 July 2007 Received: 2 April 2007 Accepted: 2 July 2007 BMC Genomics 2007, 8:208 doi:10.1186/1471-2164-8-208 This article is available from: http://www.biomedcentral.com/1471-2164/8/208 © 2007 Rubin et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Osteoporosis is frequently observed among aging hens from egg-producing strains (layers) of domestic chicken.