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Journal Final 2009.P65 ISSN 0973-8916 Current Trends in Biotechnology and Pharmacy (An International Scientific Journal) Volume 3 Issue 1 January 2009 www.abap.co.in Indexed in Chemical Abstracts and Indian Science Abstracts Association of Biotechnology and Pharmacy (Regn. No. 28 OF 2007) The Association of Biotechnology and Pharmacy (ABAP) was established for promoting the science of Biotechnology and Pharmacy. The objective of the Association is to advance and disseminate the knowledge and information in the areas of Biotechnology and Pharmacy by organising annual scientific meetings, seminars and symposia. Members The persons involved in research, teaching and work can become members of Association by paying membership fees to Association. The members of the Association are allowed to write the title MABAP (Member of the Association of Biotechnology and Pharmacy) with their names. Fellows Every year, the Association will award Fellowships to the limited number of members of the Association with a distinguished academic and scientific career to be as Fellows of the Association during annual convention. The fellows can write the title FABAP (Fellow of the Association of Biotechnology and Pharmacy) with their names. Membership details —————————————————————————————————————— India SAARC Others —————————————————————————————————————— Individuals – 1 year Rs.600 Rs1000 $100 LifeMember Rs.4000 Rs.6000 $500 (Membership and Journal) Institutions – 1 year Rs.1500 Rs.2000 $200 Life member Rs.10000 Rs.12000 $1200 (Journal only) —————————————————————————————————————— Individuals can pay in two instalments, however the membership certificate will be issued on pay- ment of full amount. All the members and Fellows will receive a copy of the journal free Association of Biotechnology and Pharmacy (Regn. No. 28 OF 2007) #5-69-64; 6/19, Brodipet Guntur – 522 002, Andhra Pradesh, India Current Trends in Biotechnology and Pharmacy ISSN 0973-8916 Volume 3 (1) CONTENTS January - 2009 Reviews Biomarkers Clinical Relevance in Cancer: Emphasis on Breast Cancer and Prostate Cancer 1 - 7 Md. Riyaz Basha, Cheryl H. Baker and Maen Abdelrahim Current trends in biotechnological production of xylitol and future prospects 8 - 36 R S Prakasham, R Sreenivas Rao and Phil J. Hobbs Plants as source of novel Anti-Diabetic Drug: Present Scenario and Future Perspectives 37 - 55 Soumya Pr. Rout, K. A. Chowdary, D. M. Kar, Lopamudra Das Research Papers Biochemical characterization of a recombinant derivative (CtLic26A-Cel5) of a 56 - 63 cellulosomal cellulase from Clostridium thermocellum Shadab Ahmed, Deepmoni Deka, M. Jawed, Dinesh Goyal, Carlos M.G.A. Fontes and Arun Goyal Rapid HPLC Determination of Venlafaxine in Microbial Biotransformation Studies 64 - 70 M. Vidyavathi, D.R.Krishna, K.V.S.R.G. Prasad And J. Vidyasagar Incidence of Candida albicans Infection in Cerebrospinal fluid - 71 - 75 A First Report from Vidarbha, Central India V. V. Tiwari and M. K. Rai Formulation and Evaluation of Solid Dispersions of an 76 - 84 Anti-diabetic Drug Abhinav Mehta, S. Vasanti, Rajeev Tyagi and Anshuman Shukla High frequency plant regeneration from callus cultures of 85 - 89 two finger millet (Eleusine coracana) cultivars A. Maruthi Rao, I. Sampath Kumar, N. Jalaja, D. Madhavi, P. Sri Laxmi, P. Nataraj Sekhar, P. S. Reddy, Rathnagiri Polavarapu, P. B. Kavi Kishor Production of Alkaline Xylanase by an Alkalo-thermophilic Bacteria, Bacillus halodurans, 90 - 96 MTCC 9512 isolated from Dung Sarika Garg , Rustam Ali and Anil Kumar Development of a Novel Transdermal Ibuprofen Ointment 97 - 104 Jithan Aukunuru, Krishna Mohan Chinnala and Viswanath Guduri Detection of telomerase activity in different cancer tissues: a diagnostic marker 105 - 110 Mahendar Porika, Uday Kiran Veldandi, Radhika Kolanu , Radhika Tippani, Rama Krishna Devarakonda and Sadanandam Abbagani Gliomastix indicus sp. nov. 111 - 112 S. Nagalaxmi, M. Vijayalakshmi and A.Subrahmanyam Information to Authors The Current Trends in Biotechnology and Pharmacy is an official international journal of Association of Biotechnology and Pharmacy. It is a peer reviewed quarterly journal dedicated to publish high quality original research articles in biotechnology and pharmacy. The journal will accept contributions from all areas of biotechnology and pharmacy including plant, animal, industrial, microbial, medical, pharmaceutical and analytical biotechnologies, immunology, proteomics, genomics, metabolomics, bioinformatics and different areas in pharmacy such as, pharmaceutics, pharmacology, pharmaceutical chemistry, pharma analysis and pharmacognosy. In addition to the original research papers, review articles in the above mentioned fields will also be considered. Call for papers The Association is inviting original research or review papers in any of the above mentioned research areas for publication in Current Trends in Biotechnology and Pharmacy. The manuscripts should be concise, typed in double space in a general format containing a title page with a short running title and the names and addresses of the authors for correspondence followed by Abstract (350 words), 3 – 5 key words, Introduction, Materials and Methods, Results and Discussion, Conclusion, References, followed by the tables, figures and graphs on separate sheets. For quoting references in the text one has to follow the numbering of references in parentheses and full references with appropriate numbers at the end of the text in the same order. References have to be cited in the format below. Mahavadi, S., Rao, R.S.S.K. and Murthy, K.S. (2007). Cross-regulation of VAPC2 receptor internalization by m2 receptors via c-Src-mediated phosphorylation of GRK2. Regulatory Peptides, 139: 109-114. Lehninger, A.L., Nelson, D.L. and Cox, M.M. (2004). Lehninger Principles of Biochemistry, (4th edition), W.H. Freeman & Co., New York, USA, pp. 73-111. Authors have to submit the figures, graphs and tables of the related research paper/article in Adobe Photoshop of the latest version for good illumination and allignment. Authors can submit their papers and articles either to the editor or any of the editorial board members for onward transmission to the editorial office. Members of the editorial board are authorized to accept papers and can recommend for publication after the peer reviewing process. The email address of editorial board members are available in website www.abap.in. For submission of the articles directly, the authors are advised to submit by email to [email protected] or [email protected]. Authors are solely responsible for the data, presentation and conclusions made in their articles/ research papers. It is the responsibility of the advertisers for the statements made in the advertisements. No part of the journal can be reproduced without the permission of the editorial office. Current Trends in Biotechnology and Pharmacy Vol. 3 (1) 1-7, January 2009. ISSN 0973-8916 Biomarkers Clinical Relevance in Cancer: Emphasis on Breast Cancer and Prostate Cancer Md. Riyaz Basha*, Cheryl H. Baker and Maen Abdelrahim Cancer Research institute, M. D. Anderson Cancer Center Orlando, 110 Bonnie Loch Ct, Orlando FL 32806, USA *For correspondence: [email protected] Abstract Key words: Biomarkers, Breast cancer, Cancer remains a major health problem Prostate cancer, Disease therapy in the world due to the dramatic increase in the number of cancer-related deaths in recent years. Introduction Biomarkers are biological candidates that are Cancer is one of the leading causes of altered due to disease condition and can serve as deaths in the world. According to World Health indicators of the disease process. Identification Organization (WHO) cancer is responsible for of clinically useful biomarkers is very critical in 13% (~30% in the United States) of deaths cancer therapy especially for the early detection worldwide in 2005. Based on the current of disease which can reduce mortality and projections, the number of worldwide cancer increase survival of life. Despite the serious deaths may rise to 11.4 million in 2030 (1). Breast concern and urgent need for the discovery of cancer is one of the five main types of cancers candidate tumor markers, the outcomes in associated with a high incidence of mortality with developing credible biomarkers are remarkably an estimated 502,000 world-wide deaths in low. Due to recent emergence of novel 2005(1). Breast cancer is the foremost cause of technologies, scientists are extensively conducting cancer related deaths among women in the United comprehensive analyses using multiple States and in the current year it is expected to approaches including genomics and proteomics record more than 240,000 new cases and more to address the issues related to low success rate than 40,000 deaths (2). Prostate cancer is among and more disappointments in developing tumor the most common type of cancer in men in the markers with clinical significance. Both the United States and it is the second largest cancer government and public sectors are using their (after lung) responsible for more male deaths. It resources to focus on multiple approaches which is estimated that 230,000 new cases and 30,000 could foster developing new biomarkers for deaths due to prostate cancer may occur in the diagnosis and early detection of cancer, thereby United States in the current year (3). The onset facilitating better understanding of cancer of prostate cancer may be multi-factorial; pathogenesis and advanced cancer care in a however genetics and diet are considered as key reasonable
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