Chemistry N E W S L E T T E R
University of Michigan Chemistry N E W S L E T T E R
and the laboratory. Our success in these Letter from the Chair endeavors is indicated by the all-time I am pleased to send greetings and high number of credit hours taught and Contents to highlight the exciting activities of bachelors degrees awarded by the depart- the Chemistry Department over the past ment last year as well as the increasing Letter from the Chair...... 1 year. Our two new faculty members, number of students taking advantage of the Paul Zimmerman and Dominika Zgid, Chemistry minors. We are excited about New Faculty...... 2 add significant strength to the areas of the development of two new majors in the Faculty News...... 3 theoretical and materials chemistry. department that increase opportunities for Faculty Profile...... 4 Both faculty members are developing undergraduates to experience the chemical innovative theoretical methods based on realm: Interdisciplinary Chemical Sci- Graduate Program News first principles with applications to solids ences and Biomolecular Sciences. Fur- Degrees...... 5 (Zgid) and molecular catalysts (Zimmer- thermore, the number of applicants to our Vaughan...... 6 man), as highlighted in this newsletter. graduate program has reached a new high. Finally, the Chemistry faculty members Awards...... 7 We are also proud to announce the have been recognized with a number of promotion of three faculty members Undergraduate Program News teaching awards: Brian Coppola received last year: Kevin Kubarych and Nikolai the Robert Foster Cherry Award for Great Degrees...... 8 Lehnert to Associate Professor with tenure Teaching as well as the Provost’s Teaching Awards...... 9 and John Wolfe to Professor with tenure. Innovation Prize and John Wolfe received These faculty members were promoted Summer Programs ...... 9 the LSA Excellence in Education Award based on their outstanding accomplish- and the LSA John Dewey Award. Gifts...... 10 ments in the areas of research, teaching Alumni News ...... 11 and service. Finally, the research excel- Both educational and research missions lence of the Chemistry faculty members of the Chemistry Department are growing In Memoriam ...... 12 was recognized with numerous external and thriving, despite budget challenges. Faculty Listing...... 14 awards over the past year including: The generous support of our research and Alumni Reply Hashim Al-Hashimi received the Founders teaching efforts by alumni (and others) Form ...... inside back cover Medal from the Conference of Magnetic has become increasingly important for Resonance in Biological Systems; Charles maintaining and enhancing excellence in Donations...... reply envelope flap L. Brooks, III was the recipient of the all areas of the department, including sup- Protein Society’s Hans Neurath Award, porting undergraduates in research and at- Robert T. Kennedy received the Marcel tracting outstanding faculty. The students Golay Award and the Eastern Analytical and faculty thank all of the benefactors Symposium Award, Mi Hee Lim received of the department, including Professors a Alfred P. Sloan Research Fellowship, Janet Bluemel and John Gladsyz (see Anna K. Mapp received an ACS Arthur C. Alumni News) for their gifts. I hope that Cope Scholar Award and Melanie Sanford you enjoy hearing about the Department was awarded the Theime-IUPAC Prize in in this newsletter and I invite you to visit 2012 Synthetic Organic Chemistry and the Paul the Department anytime that you are in N. Rylander Award. town. I look forward to talking with you. The Regents of the University of Michigan: Julia Donovan Darlow, Laurence B. Deitch, Denise Ilitch, Olivia Best wishes, P. Maynard, Andrea Fischer Newman, Andrew C. Richner, S. In addition to achieving research Martin Taylor, Katherine E. White, Mary Sue Coleman, ex officio. excellence, our Department strives for Carol Ann Fierke, Chair, Jerome and Mary Sue Coleman, president. outstanding pedagogy and innovation in Isabella Karle Professor of Chemistry and The University of Michigan is an equal opportunity/affirmative teaching chemistry both in the classroom Professor of Biological Chemistry action employer.
2012 U-M DEPARTMENT OF CHEMISTRY Spotlight: Profiles of New Faculty often attainable via other means. However, Faculty News presented by the National Organization for excellence in directing the Sloan many first principles methods are too for Professional Advancement of Black Minority Graduate Program and making We highlight faculty members who have joined the Department since the last newsletter. costly for routine use in realistic systems Hashim Al-Hashimi has received the Chemists and Chemical Engineers. Ted exceptional contributions in mentoring Their appointment speaks well for our future. due to poor scaling with system size. To Founders’ Medal from the International has also been invited to serve as a Sigma minority graduate students. alleviate this problem, our research group Conference of Magnetic Resonance in Xi Distinguished Lecturer. He also Kathleen V. Nolta has received develops and applies state-of-the-art first- Biological Systems (ICMRBS) at their 25th received a 2012 Rackham Distinguished the 2012 Excellence in Concentration Dominika Zgid, Assistant try, physics principles methods and support tools for meeting held in Lyon, France in August Faculty Achievement Award from the UM Advising Award. The award recognizes and materi- the description of molecular catalysts and 2012. The award is made in recognition Rackham Graduate School. Professor her work as a mentor and advisor to PhD: University of Waterloo, Canada als science. solar energy conversion systems. of exceptional contributions by a young Our goal is Robert T. Kennedy received the undergraduate students in the Department PostDoc: Cornell University, Columbia Discovering mechanisms of catalysis scientist for the development and/or to develop 2012 Marcel Golay Award honoring his of Chemistry at UM. University to guide experiments toward increased progress in the field of magnetic resonance theoretical outstanding contributions to important Electronic Structure of Molecules and rates and selectivity. New methods are in biological systems. Ayyalusamy (Rams) Ramamoorthy tools that aspects of chromatography research. Crystalline Systems being developed in the group to navigate received a UM Rackham Faculty give access Charles L. Brooks, III is the 2012 The award was made at the International complex reaction pathways with minimal Recognition Award for 2012. This award Newly emerging “electron correlation” to directly recipient of the Protein Society’s Hans Symposium on Capillary Chromatography computational and human effort. These is given in recognition of his outstanding devices made out of transition metal oxide experimen- Neurath Award. The award recognizes and Electrophoresis held in Riva del tools (one example is the Freezing String contributions to biological solid-state heterostructures (Sr(Zr)TiO3), battery tally rele- an individual who has made recent Garda, Italy on May 27. He also received Method), allow the study and discovery NMR spectroscopy and biophysical materials LiMPO4 (with M = Mn, Fe, vant quan- contributions of unusual merit to basic the 2012 Eastern Analytical Symposium of catalytic processes even with limited chemistry as well as his stellar teaching Co, and Ni) and new molecular magnets tities. We research in the field of protein science, Award for Outstanding Achievements a priori chemical insight. These methods and services to science and the UM. used in quantum computing are at the develop and apply codes that describe including but not restricted to the in Separation Science in November at are applied to difficult energy-related heart of new experimental developments two types of electronic motion (i) weakly chemistry, design, folding, structure or Somerset, NJ. Paul Rasmussen became Professor in materials and chemical sciences. Such problems such as CO2 reduction and meth- biological function of proteins. Brooks Emeritus in 2006 but remains active in correlated electrons originating from the Nancy Kerner is a recipient of the experimental progress poses many ques- ane conversion. This approach identifies was acknowledged at the 26th Annual chemistry. For the past four years he delocalized “wave-like” s- and p-orbitals Sloan Consortium Effective Practice tions to our theoretical understanding. The the strengths and limitations of existing Symposium of the Protein Society in has worked part-time in the laboratory responsible for many electron correlation Award. Nancy and her colleague Brenda answers can be found using a combination catalysts at an atomistic level to aid in San Diego, CA in August with a session of Professor Levi Thompson in the effects in molecules and solids that do not Gunderson received the award for their of modeling and theory to support the the design of improved catalytic systems. in his honor. Department of Chemical Engineering at contain transition metal atoms, (ii) strongly project, “Integration of Technology Into experiment. In our group, to tackle these UM, where he is involved with research on correlated electrons residing in the d- and Characterizing the fundamental be- Brian Coppola has been named by Undergraduate Education via Cross- important questions, we are developing super-capacitors, redox flow batteries and f-orbitals that remain localized and behave havior of excited states in light harvesting Baylor University to receive the 2012 Disciplinary Pollination.” controlled, reliable, and systematically im- electrochemical catalysis. He regularly “particle-like” responsible for many very materials. Solar cells and photocatalysts Robert Foster Cherry Award for Great provable theoretical methods that describe Robert L. Kuczkowski completed teaches a course, “Cars, Energy, and interesting effects in the molecules contain- may be tuned to substantially higher ef- Teaching. The correlation effects and are able to treat service as a program officer in the Sustainability,” in the Program in the ing d- and f-electrons (transition metal na- ficiency when the character and interac- Cherry Award is solids and large molecules realistically. Chemistry Division of the National Environment at UM. Finally Paul has no-particles used in catalysis, nano-devices tions among electronically excited states the only national Science Foundation this past September. founded a company, Vinazene, Inc., which Our work is interdisciplinary in nature with Kondo resonances and molecules of are known. This level of detail, however, teaching award Since becoming Professor Emeritus in is developing energy storage materials for and we connect three fields, chemis- biological significance - active centers of is especially hard to obtain due to the presented by 2002, he has served in several programs use in redox flow batteries. metalloproteins). The mutual coupling high cost of existing electronic structure a college or at NSF including instrumentation, of these two types of electronic motion methods that can treat excited states. New university for Melanie S. Sanford has become the chemistry centers and undergraduate is challenging to describe and currently methods (such as Restricted Active Space exceptional Moses Gomberg Collegiate Professor of research (REU). Department of Chemistry only a few theories can properly account Spin Flip) allow investigation of single teaching. Chemistry. This summer she received the Newsletter for both types of electronic correlation and multiple exciton states in realistic Coppola will Mi Hee Lim received a 2012 Alfred 2012 Theime-IUPAC Prize in Synthetic effects simultaneously. models of molecular light harvesters and is published once a year by the Department receive the P. Sloan Research Fellowship. Sloan Organic Chemistry. The award was made th of Chemistry at the University of Michigan, photocatalysts. The mechanistic informa- $250,000 award Fellowships have been awarded since 1955 at the 19 International Conference on Ann Arbor, MI 48109-1055 tion gained from these studies will lead to and an additional and are given to early career scientists in Organic Synthesis (ICOS-19) held in the development of highly efficient solar $25,000 for the Chemistry Department at recognition of achievement and potential Melbourne, Australia this July. Melanie materials such as those that employ singlet UM. He will be in residence at Baylor to make substantial contributions in their is the eleventh recipient of the prize which Paul Zimmerman, Assistant fission, where a single photon is converted during their Spring 2013 semester. fields. She also received the 2012 Paul D. is awarded to scientists under the age of
Professor into two electron-hole pairs. His acceptance speech highlighting Saltman Award, which is given annually 40 whose research has had major impact his storytelling approach to teaching by the Gordon Research Conferences to on synthetic organic chemistry Printed on Recycled Paper PhD: Stanford University is available at http://www.baylor.edu/ an outstanding young investigator in the PostDoc: University of California- The Organic Reactions Catalysis cherry_awards/ field of biological inorganic chemistry. Berkeley Society has announced that Melanie is Chair: Carol Fierke Finally she has received the ACS Women Physical Chemistry, Theoretical Chem- Barry D. Dunietz has left the the recipient of the 2012 Paul N. Rylander Editor: Arthur J. Ashe, III Chemists Committee Leadership Award Publication: Agnes Soderbeck istry University. He is now at Kent State Award. The award is sponsored by BASF for 2012. Alumni News: Arthur J. Ashe, III, University. and is awarded annually to researchers Robert Kuczkowski Anna K. Mapp has received a 2012 who have made significant contributions Alternative energy research can greatly Theodore G. Goodson, III has been ACS Arthur C. Cope Scholar Award. The in the application of catalysis in organic benefit from ab initio simulation that named the Richard Barry Bernstein award was given at the recent national reactions. She will be awarded the provides molecular level insight into the Collegiate Professor of Chemistry. In 2011 Web Address: ACS meeting in Philadelphia. 2013 national ACS Ipatieff Prize. The nature of chemical bonds and excited he received the Percy L. Julian Award for http://www.umich.edu/~michchem award recognizes outstanding chemical states. The level of detail found using Outstanding Research in Pure and Applied Adam J. Matzger has received a experimental work in the field of catalysis E-mail: [email protected] these methods is extremely high and not Science and Engineering. The award was 2012 Imes and Moore Faculty Award or high pressure, carried out by an
2 2012 U-M DEPARTMENT OF CHEMISTRY 3 individual of any nationality who is not Nils G. Walter has been selected as a John P. Wolfe received the 2012 LSA Maryland, Kalamazoo, and Oberlin. He is Besides research and teaching, Bob has many years. Presently he is Director of the over 40 years of age. Special weight is 2011 AAAS Fellow. The award honors John Dewey Award. This award is made to routinely amazed at the accomplishments been involved in a number of other activi- NIH-funded Microfluidics in Biomedical given to independence and originality. his distinguished contributions to the field the person who best models the full range of these students as they move forward ties. In the department Bob led develop- Sciences Training Program. He is also The prize is awarded every three years. of biophysical chemistry, particularly by of Dewey’s talents: scholarly productivity, into their own careers. Working with his ment of the most recent long range plan Associate Editor of Analytical Chemistry. applying experimental and computational provision of leadership, and engagement students and post-docs he has published and served on the executive committee for Melanie has also been selected to biophysical approaches to elucidation of with and the care of students. He has ~175 research papers. receive the 2013 Tetrahedron Young the function of non-protein coding RNAs. also received a 2012 LSA Excellence in Investigator Award in Synthetic Chemistry. Last term he was on sabbatical as an Education Award She will write an article for a Tetrahedron Alexander von Humboldt Visiting Scholar Journal Symposium-in-Print. Finally she at the University of Frankfurt in the group has been given the Classical High School of Professor Harald Schwalbe. Distinguished Alumni Award for 2012. Graduate Program News
Graduate Degrees - Masters & Ph.D August 2011, December 2011, May 2012 & August 2012
Faculty Profile insulin secretion and defects that occur in methods are being applied in a wide range Doctorates diabetes. Another project was development of projects. His work on beta cells have of fast (0.1 to 10 s) electrophoretic sepa- continued with development of microflu- Thaddeus Boron Vincent Pecoraro Colin Jennings Michael Morris Robert Kennedy was born in rations. One application idic chips that can monitor insulin secre- Control of Single-Molecule Magnetic Properties Using Metalla- High Mass and Temporal Sensitivity Quantification of Biochemi- Sault Ste. Marie, MI and raised of this work has been tion from single islets of Langerhans over crowns cal Species in Microfluidic Devices in Kentucky and Florida. As an use of electrophoresis to long term and metabolomic methods for Jameson Bothe Hashim Al-Hashimi Austin Kizzie Adam Matzger undergraduate at University of detect and characterize studying the metabolic changes involved Investigation of the Formation of Z-DNA and Other Non-Canon- Synthesis and Characterization of Microporous Coordination Florida he majored in chemistry non-covalent complexes in insulin secretion. The lab is expanding ical DNA Conformations Using a Combined Spectroscopic and Polymers as Adsorbents for Carbon Dioxide Capture Biochemical Approach with the intent of becoming a (e.g., for immunoas- to other cell types including adipocytes Asako Kubota Melanie Sanford veterinarian. An undergraduate says, aptamer assays, with the goal of generating “body-on-chip” Zach Buchan John Montgomery Pd-Catalyzed Oxidative Functionalizations research experience with Bill and protein-protein in- systems with integrated chemical analysis Sugar Silanes in Carbohydrate Synthesis: Applications Towards Site-Selective Glycosylation Wei Li John Montgomery Dolbier involving synthesis of teractions). The fast elec- tools. Droplet microfluidics is opening up a Nickel-Catalyzed Coupling Reactions difluorocarbene adding reagents trophoretic separations new research direction in high-throughput Jing Chen Anne McNeil convinced Bob to change plans also led to the concept screening. This work combines droplet Sensing via Analyte-Triggered Gelation: Molecular Design and Matthew Lorenz Robert Kennedy Implementation Development and Application of Metabolomic Techniques for and develop a career in chem- of a “separations-based sample manipulation with fast electro- Identification and Quantification of Intercellular Metabolites Rel- istry. He earned a Ph.D. at the sensor” where a con- phoresis and mass spectrometry to en- Natalie Crist Mark Meyerhoff evant to Glucose Stimulated Insulin Secretion in B-cells University of North Carolina where he tinuous sampling probe is coupled to fast able screening of previously intractable Methods for the Detection of S-Nitrosothiols and Nitric Oxide in studied miniaturized separation techniques separations to allow chemical monitoring. targets. Finally, a large portion of the lab Blood and Breath Anna Merkle Nicolai Lehnert Investigation of the Electronic Structure and Photolability of Cop- and pioneered their application to single This work has been used extensively for is devoted to developing and applying Leila Foroughi Adam Matzger per-, Manganese-, and Ruthenium-Nitrosyl Complexes cell analysis under the direction of Jim monitoring neurotransmitters in the brain. separations-based sensing to neurochemi- Polymers as Heterogeneous Growth Promoters for Protein Crys- Jorgenson. He furthered his bioanalyti- While at UF Bob’s work was recognized cal monitoring. A recent project, which tallization Sethu Pitchiaya Nils Walter with several awards including a Teacher typifies this work, identified enkephalins Probing miRNA Activity In Vitro and Inside Cells Using Single cal interests through a NSF post-doctoral John Brannon Gary Melanie Sanford Molecule Microscopy fellowship with Mark Wightman, also at of the Year award in the College of Lib- as key signaling molecules in motivating Next Generation Shilov Catalysis: Ligand Design and Compu- UNC. eral Arts and Sciences, Beckman Young feeding behavior. During his 10 years at tational Analysis for Improved Catalysis in C-H Activation and Joy Racowski Melanie Sanford Investigator, and Presidential Early Career Michigan Bob has been recognized with Functionalization Chemistry New Reactivity of High Oxidation State Palladium Complexes In 1991 Bob was hired as assistant Award in Science and Engineering. a number of awards including two NIH Xiaomu Guan Carol Fierke Ahleah Rohr Daniel John Wolfe & Mark Banaszak Holl professor at University of Florida where he MERIT awards, a McKnight Foundation Investigations of Polymorphic Germylene Structures, Experimen- After getting his fill of sunshine and Mechanistic Studies of Protein Lipidation: Yeast Palmitoyltrans- taught analytical chemistry and developed Award for Innovations in Neuroscience, tal Calculations of a New Boron-Sulfur Heterocycle and Assess- alligators, Bob moved to University of ferase Akrlp and Protein Farnesyltransferase a broad research program at the interface of and the Golay Award for lifetime achieve- ment of a Curriculum Addressing Safety in the Undergraduate Michigan in 2002 along with 10 graduate biology and chemistry. During his educa- ment in chromatography. Kevin Hartman A. Ramamoorthy Laboratories tion he became fascinated by the concept students and post-docs. Amazingly no gear Characterization of the Amyloidogenic Peptides Amylin and PAP248-286 Danielle Schultz John Wolfe of using chemical tools and instrumenta- was broken during the move and the lab Bob has been fortunate to work with New Palladium– and Gold-Catalyzed Alkene and Alkyne Difunc- tion to gain insight into living systems. was quickly up and running. At UM Bob many excellent students and post-docs. Katie Hersberger Kristina Hakansson tionalization Reactions for the Efficient, Stereoselective Synthesis This interest has been the driving force has continued his research in bioanalytical Forty-four students have graduated from Metal-Oxide Enrichment and Gas-Phase Characterization of of Heterocycles and Beta-Alkoxy Ketones for his research program. A key project chemistry. He has enthusiastically taken his group with PhDs (with four more ex- Sulfopeptides using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Hangtian Song Kristina Hakansson was development of a microelectrode advantage of the outstanding colleagues pected this fall) and 19 post-doctoral fel- Novel Fourier Transform Ion Cyclotron Resonance Mass Spectro- that could detect insulin secretion from in chemistry, engineering, psychology, lows have been through the lab. Kennedy Amanda Hickman Melanie Sanford metric Strategies for Acidic Biomacromolecules: Characterization single beta-cells. This method allowed physiology, and pharmacology to develop group alumni are presently at many differ- Catalyst Controlled Site-Selective C-H Functionalization and Quantification an interdisciplinary research effort. A focus ent companies including Abbot, Amgen, single exocytotic events to be detected Jiyoung Hong Kate Carroll Kara Stowers Melanie Sanford and provided substantial insight into the for analytical instrument and methods BP, Dow, Eastman, Eli Lilly, Merck, Pfizer, Toward the Discovery of Small Molecules that Target Latent Mechanistic Studies and Synthetic Applications of Ligand Di- function of these important cells. This research has been investigation of chemi- Proctor & Gamble, and Vertex. Students Tuberculosis Infection rected Pd-Catalyzed C-H Functionalization work was the starting point for a long- cal separations, microfluidics including taking academic careers are professors at “droplet fluidics”, mass spectrometry, and a wide range of institutions including Vir- Joe Jankolovits Vincent Pecoraro Christopher Taylor Anna Mapp running research project aimed at better Using the Structural Versatility of Lanthanide Metallacrowns to Tune I. The Utility of Activation Domain Mimics as Targeted Inhibitors understanding biochemical mechanisms of HPLC-MS based metabolomics. These ginia, Arizona, Minnesota, Florida State, Anion Recognition, Self-Assembly, and Luminescence Properties of Transcription. II. The Design and Implementation of a Peer-
4 2012 U-M DEPARTMENT OF CHEMISTRY 5 Lead Modul in Practical Research Ethics Heterocycles and Enantioselective Synthesis of Diols and Amino- Kasimir Fajans Dissertation Award be given to a graduate student to continue research in analytical Alcohols chemistry. The award provides for a summer half-term stipend. Ben Thompson John Montgomery On February 22, 2012 Dr. Matthew V. Schulmerich received Anne Vazquez Zhan Chen The Reductive Couplings of Enones and Alkynes and Application the Kasimir Fajans Award for the most outstanding chemistry Robert W. Parry Award to Heterocycle Synthesis Correlating Surface and Buried Interfacial Structures to Polymer dissertation for the years 2008-2009. Dr. Schulmerich is currently Zachary Bryan McNeil Adhesion The Robert W. Parry Awards are made possible through the Amanda Ward John Wolfe a postdoctoral fellow at the University of Illinois at Urbana- generous donations of alumni, friends, industrial donors and the Method Development for the Stereoselective Synthesis of Het- Maximillian Bailor Hashim Al-Hashimi Champaign in the Department of Bioengineering, where he works RNA Topology as a Framework for Structure, Dynamics and students of Professor Parry. It is awarded to a graduate student erocycles with Professor Robit Bharhava. His lecture was titled, “Raman Adaptation who has shown excellence in research in inorganic chemistry. This Crystal Young Katrin Karbstein Spectroscopy in the Presence of Light Scattering: Polymer Model award provides for a summer half-term stipend. Rok1ng the Ribosome Assembly Boat: An Investigation of the Ajdin Kavara Mark Banaszak Holl Systems and Applications Towards Biomedical and Agricultural DEAD-box Protein Rok1 and its Co-factor Rrp5 C-H Activation and Cyclizations using Stannylenes Research.” Kasimir Fajans’ son Dr. Stefan Fajans and his mentor Peter A.S. Smith Fellowship Summer 2011 Cornelius Kristalyn Zhan Chen Professor Michael Morris attended a Chemistry Department Brian Larsen Nagorny Surface Studies of New Anti-Fouling Polymers by Sum Frequency reception prior to the lecture. Dr. Schulmerich’s name has been The Peter A. S. Smith Fellowship was endowed in 1995. The fel- Andrew Boughton Zhan Chen Generation placed on a bronze plaque on permanent display in the main lowship is awarded to a graduate student who is doing research in Sum Frequency Generation and Molecular Dynamics Studies of synthetic organic or inorganic chemistry. This award provides for Biomolecular Orientation at Model Interfaces Chen Li David Lubman conference room of the chemistry building. Protein Expression and Glycosylation Level Change Associated a summer half-term stipend. Di Si Raoul Kopelman Pancreatic Cancer Margaret & Herman Sokol Graduate Summer Research PEBBLE nanosensors for calcium and zinc measurements Fellowship Laura Zimmerman Mark Meyerhoff Pyrroloquinoline Quinone (PQQ) Labeling Moieties for the Ultra- Ning Wang Hakansson Herman Sokol (MS 1940) and his wife, Margaret, established this Summer 2010 Sensitive Detection of Biomolecules fellowship in 1983. The award supports a graduate student who Katie Cychosz Adam Matzger has demonstrated excellence in research. Microporous Coordination Polymers as Selective Adsorbents for Chelsea Huff Graduate Awards Complex Matrices Masters Heidi Alvey-Pedini Kelsey King Research Excellence Award Jonathan Mortison David Sherman Wenyi Cai Se Ryeon Lee Departmental Awards Nicholas Babij Wolfe John King Kubarych Chemical and Biochemical Interrogation of Molecular Specificity Monica Lotz Paul Bruno Mapp Akiko Kochi Lim Brendan Clifford American Chemical Society Outstanding Graduate Student in Modular Polyketide Synthases Gabriel Roman Melendez Zachary Bryan McNeil Yuwei Liu Chen Andrew Crawford Award for Research and Teaching Sabrina Peczonczyk Tyler Carter Szymczak Xin Liu Fierke Amberlyn Wands Anna Mapp Debasis Das Lauren Goodrich Lehnert Characterization of the Dynamic Interactions of Transcriptional Nicholas Roe Nathan Cichowicz Nagorny John-David Kenneth Fletcher This award is given by the Huron Valley Section of the Ameri- Activators Lauren Soblosky Ananya Dutta Matzger McElderry Morris Christina Franzese can Chemical Society to recognize achievement in teaching and Molly Soper Lauren Goodrich Lehnert Sharon Neufeldt Sanford Natalie Giampietro John Wolfe Joseph Furgal research by a graduate student. Development of Reactions for the Stereoselective Synthesis of Ping Guo Ning Wang Junsi Gu Maldonado Bo Peng Meyerhoff Neil David Hershey Anna Wagner Robert & Carolyn Buzzard Graduate Chemistry Student Linjie Han Ruotolo Broc Smith Sension Leadership Award Beth Haas Biteen Peng Song Kennedy Se Ryeon Lee McNeil Xiaoguang Hao Bartlett Surma Talapatra Geva The award recognizes a student who has shown leadership in the Martyn Haynes Montgomery Ning Wang Hakansson Department. It was provided by Bob & Carolyn Buzzard. Rui Huang Ramamoorthy Sung-Hei Yau Goodson The Victor C. Vaughan Symposium Arnold of California Institute of Technology. In between there Florence Fenwick Outstanding Graduate Student Instructor Alexander Johnson- Fangting Yu Pecoraro were six 25 minute talks by graduate students. Student posters Award Buck Walter The Vaughan Symposium (http://umich.edu/~vvaughan/) was were presented in morning and afternoon sessions. There were Erik Guetschow Kennedy held in the Chemistry Department on August 2, 2012. The sym- a total of 260 attendees including twelve scientists from Dow. Presented to graduate students who taught undergraduate courses posium is named in honor of Victor C. Vaughan (1851-1921) who Vaughan Symposium Awards All registrants received a free lunch and a symposium t-shirt. in Chemistry during the 2011-2012 academic year. Recipients was one of the first students to graduate from the University with are selected based on their contribution to innovation in the lab Dow Chemical Oral Presentation Travel Award a PhD in Chemistry (1876). Dr. Vaughan subsequently earned Drs. Arnold, Walsh and the Dow representatives selected the oral Se Ryeon Lee presentation by Se Ryeon Lee (Advisor: Anne McNeil) to receive or classroom, teaching evaluations and written recommendation an MD from Michigan in 1878 and went on to a distinguished of a professor. This award is provided by the Florence Fenwick the award for the outstanding oral presentation. The award consists Oral Presentation Travel Award career in medicine. He served as Dean of the Medical School Memorial Fund. of an $800 travel award to attend a scientific meeting. There were Jeremy Feldblyum 1891-1921 and president of the AMA (1914-5). Beth Haas two other awards for oral presentations and 21 for excellent posters. Milton Tamres Outstanding Teaching Award The Vaughan Symposium was designed by and is run by The awardees are listed in this newsletter. These awards of $400 Beth Haas Biteen Poster Session Travel Awards Shi Jin Kennedy Michigan Chemistry Graduate Students. It serves as a venue in each are to be The late Professor Milton Tamres established this award to rec- Neranga Kristin Ko Soellner which to share exciting research taking place within the Department used to attend ognize outstanding cumulative teaching service. Mrs. Françoise Abeyesinghe Goodson Akiko Kochi Lim of Chemistry. Originally named Pecrum, the first symposium was a scientific Tamres continues to maintain the support for this award. Tim Berto Lehnert Yi Liao Biteen held in 2003. Through participants presenting their work to the meeting. We are Alumni Fund Outstanding Graduate Student Research Award Tanya Breault Bartlett Solymar Negretti- Department as a whole, students foster collaborations, inspire new grateful to the John King Kubarych Zachary Bryan McNeil Emmanuelli Montgomery avenues of research, and nurture a growing sense of community Dow Chemical This award is provided by the Alumni Fund to a graduate student Amanda Cook Sanford Shuai Niu Ruotolo within the Department. The symposium has become an annual Foundation for for outstanding research. Ananya Dutta Matzger Laura Pfund Matzger tradition within the Department of Chemistry. their generous Joseph Furgal Goodson/Laine Sameer Phadke Soellner Departmental Fellowships Garrett Goh Brooks This year’s symposium was chaired by Amanda Dugan. It support of these Yuta Suzuki Marsh Junsi Gu Maldonado Anna Wagner Sanford started and finished with two excellent plenary lectures by Dr. awards. George Ashworth Analytical Chemistry Fellowship Michael Howard Fierke Yingda Ye Sanford Terence Walsh of Dow AgroSciences and Professor Frances Yi Liao Biteen The George Ashworth Endowment provides for a fellowship to Chelsea Huff Sanford
6 2012 U-M DEPARTMENT OF CHEMISTRY 7 Non-Departmental Awards Rackham Predoctoral Fellowship Undergraduate Awards Jerome and Isabella Karle Award in Physical Science Joseph Braymer Lim Sean Michael Collins National Science Foundation Fellowship Alexander Johnson-Buck Walter Alaina DeToma Lim Alpha Chi Sigma Outstanding First Year Student Award Merck Index Award to Outstanding Seniors Alina Borovika Nagorny Rackham Graduate Student Research Grant Justin Wang Henry Kuang Jessica Rabuck Ruotolo Roche 2012 Excellence in Chemistry Award Alumni First Year Achievement Awards Summer Research Awards Yingda Ye Sanford Rackham Science Awards Andrew Glatz, Vinay Guduguntla, Alex Kokaly, Matthew Each year, thanks both to endowment funds and the gener- Jeremiah Alicea Wolfe Thimm, KayleeVan Dommelen, Sheri Vanomen, Abbey Wein- ous donations of private and industrial sponsors, we are able to Eli Lilly Travel Award Eli Fahrenkrug Ruotolo stein, Jialing Zhou support a large number of students for summer undergraduate Allison Knauff Montgomery Peipei Hu Chen Alumni Outstanding Awards research. Based on recommendations by the faculty, as well as Rackham Outstanding GSI Award Ashley McQuarters Lehnert Second Year — Sepideh Ashrafzadeh their academic records, the selection committee recommended the Alexander Johnson-Buck Walter Tiffiny Micyus Sanford Third Year — Benjamin Levin following students for summer 2012 research support. Rackham Centennial Spring/Summer Fellowship Jessica Rabuck Ruotolo Senior — Holly Williams Nicholas Roe Lehnert James E. Harris Scholarship Award: Timothy Berto Lehnert American Chemical Society Analytical Chemistry Award Shuai Niu Ruotolo Shin Hee Lee, Patrick Kurecka, Tim Pow, Monica Ray Training Grants Dakota Suchyta Rackham One-Term Dissertation Fellowship Proteome Informatics of Cancer Training Program (PICTP) American Institute of Chemists Award Albert Euclid Hinsdale Memorial Endowment: Anna Merkle Lehnert Molly Soper Ruotolo Biochemistry: Robby Lentz Vincent Lizzio, Ben Maynard, Halley Rycenga, Dan Semaan, Wei Li Montgomery Chemistry: Joseph Reed Blane Zavesky Ash Stevens Undergraduate Research Award in Organic PPG Undergraduate Award: Chemistry Courtney Talicska Newly established in 2012, this award is presented by Ash Stevens, a chemical process development company, to recognize William G. Smeaton Memorial Award: an undergraduate doing outstanding work in the area of organic Brenden Magnan, Frank Mei, Wei Wei Wu chemistry. Seth Klapman Undergraduate Program News Margaret and Herman Sokol Endowment Award: CRC Outstanding Achievement Award Kent Brummel, Josh Kurtz, Justin Liedel, David Quist, Sheng Ray Strobel Zheng Undergraduate Degrees Seyhan N. Ege—WISE Award August 2011, December 2011, May 2012 & August 2012 Jackie Wang Summer Undergraduate Research Program Award: Brianna Chamberlin, Laura Essex, Nirbhay Jain, Elizabeth Bachelor of Science Honors College Vanko Award Melissa Gildenberg Jennifer Nimtz Victor Gu Keenan, Seth Klapman, Ben Levin, Andrew Phillips, Heeju Biochemistry Joshua Bornstein Linxuan Hao Kevin O’Neill Ashley Hartmann Ryu, Emily Seeley Nicole Stegmeier, Ian Vonwald Fulla Abdul-Jabbar Kimberly Haupt Tiffany Pham Bradley Keller Huron Valley Section Outstanding Student Leadership Husam Alghanem Marten Hawkins Timothy Pituch Joseph Reed Award Abdallah Ali Kyle Heckaman Randy Planegger Jr. Burton Simpson Melissa Gildenberg Arafat Ali Joel Hrit Jonathan Qiao Bachelor of Science in Jeffrey Atkins Catherine Hwang Shaoon Rahman Chemistry Mark Austin Alexis Jensen Alexander Sapick Andrew Bielawski Asia Body Brice Jurban Nicholas Sattelberg Daniel Camacho Undergraduate Programs Richard Boehnke Nayiri Kaissarian Bruce Schultz Sean Collins Joshua Bornstein Yi-Cheng Kao Erin Shea Robert Collison Research Experiences for Undergraduates Alexandra Bourgis Kristin Kopec Remzi Sipahi Daniel Cummins (REU) 2012 Brian Chen Kasha Krul Alexander Stark Xiaodi Gao Yang Chen Clara Lee Joshua Symes Allan Golden This past summer, we hosted an REU site supported by the th Jane Cheng Patrick Lee Seena Tehrani Aaron Goodman National Science Foundation for the 24 year. We had 16 par- Winnie Cheung Robert Lentz Rohit Vyas Matthew Hillyer ticipants from across the United States working full time for 10 Students from Peking John Chism Elton Li John Wallington Scott Hogan weeks in our laboratories. University Robert Collison Elizabeth Limback Christopher Walters Heeyeon Kim Hans Dalton Jimmy Lin Alan Wang Unfortunately, the Chemistry Division at the NSF has curtailed Yuzhong Liu its funding for international REU programs, and so we were not Angela Degraaf Emefah Loccoh Jackie Wang Elizabeth McDonagh able to carry out our REU Site in China, which we had been do- Nicholas DeHaan Angelical Martin Elizabeth Williams Meghan Orr ing since 2007. The companion program, in which students from Vishan Dhamsania Austin McHenry Peter Xie Tanvi Ratani Beijing come to UM, was also reduced in size this year because Robert Dikeman Alan McLean Lindy Zhang Ian Rust Anne Dosey Lucas McShosh Alexander Ziegler Whitney Smith of diminished funding from our industrial sponsors. However, we Elli Fackelman Nathan Merrill Bachelor of Science. Jacob Van Oosterhout did host 6 chemistry students from Peking University, and our Bryan Fiema Amber Miller Chemistry Concentration Victoria Washington colleagues in MCDB, EEB, and the Life Sciences hosted another Vivienne Fong Brittney Miller Christopher Anderson Holly Williams 6 from Tsinghua University. Benjamin Gandomani Saman Mirkazemi Jonathan Bassman Jerry Yan Ashley Gibbons Phil Nahirniak Kitae Chang REU students
8 2012 U-M DEPARTMENT OF CHEMISTRY 9 Lourdes I. Puig Kelly McDow Gifts James M. Reh Steven H. McKinley Alumni News Nancy M. Rickey Christer E. Nordman Contributions from private and corporate donors received from Steven C. Rifkin Gordon A. Parker E-Mail your news: [email protected] July 1, 2011 – June 30, 2012. Thomas M. Rosseel David R. Parker Update your contact information: http://www.umich.edu/~michchem/alumni/ Charles A. Roth Norman R. Smith Warren K. Russ John C. Whitmer If errors or misstatements are noted in any of the following items, the Editors of the Newsletter would Chair’s Discretionary Fund Brian R. Dixon Russell E & Margaret G Price David L. Zellmer Antone L. Lott Richard H. Douglas appreciate such being called to their attention. Corrections can easily be inserted in the next edition. Gloria E. Salavarria Edwin P. Przybylowicz Dow Chemical Company Fdn Undergraduate Research in James M. Samanen Mekhala Raghavan Dow Corning Corporation Chemistry Roxanne M. Drnevich Melanie S. Sanford Chemistry Alumni Fund Helen S. Schaefer Mary E. Sheridan Sultan T. Abu-Orabi (PhD 1982, Arthur Ashe) was elected Kim Haupt (BS 2012) will begin graduate studies at the Univer- David V. Duchane Ruth A. Gustafson BASF Corporation David W. Ebdon Joel L. Schmiegel Secretary General of the Association of Arab Universities. This sity of Wisconsin, Madison. She did an undergraduate project Richard M. Scribner Cengage Learning Sue E. Delos Elaine G. Shafrin association is the umbrella organization of 240 universities in with Nils Walter. Dominion Foundation Stephen H. Shane Ash Stevens Undergraduate Eli Lilly & Company Fdn 22 Arab countries. Judith L. Doyle Larry E. Fink Elvera B. Shappirio Research Award Kathy (Dien) Hillig (PhD 1983, Michael Morris) has completed Helen E. Fan Zhong-You Shi Kathryn L. Fok Ash Stevens, Inc. Zain Bengali (BS 2001) completed a postdoctoral at the National 28 years in various positions for BASF Corporation. Working at Peter S. Friedman Gerald D. Fong Thomas G. Siracusa Leigh Charles Anderson Memo- Mary Ellen Heyde Peter Fox Hilary E. Snell Institutes of Health in Molecular Virology. He started work as Wyandotte, MI, Kathy started in the Environmental Analytical Kurt W. Hillig Shirley S. Fraley Charles S. Spencer rial Fund a Research Scientist in October 2011 with Intrexon. He and his Lab and subsequently moved to the Ecology Group to consult on George B. Lowrie Thomas J. Gallagher Jack Sweet Irving M. Adler wife have recently had their second child and live in northern commercial environmental labs used in compliance testing. She Michael A. Mazzuchi William L. Gebo Ashley E. Tan Seyhan N. Ege Junior Faculty next moved to the product regulation area, dealing mostly with Veronica A. Miller James H. Thirtle Virginia. Andrew J. Gesell Development Award Geraldine C. O’Laughlin Lazarus D. Thomas EPA TSCA regulations. She now leads the Raw Material Team Thomas J. Giordano Marjorie L. Carter Murphy Brasuel (PhD 2002, Raoul Kopelman) began his service Harold F. Sandford John K. Tomlinson for the IS group responsible for Enterprise Master Data. Her Michael D. Gordon Gerald D. Fong as Chair of the Department of Chemistry and Biochemistry at Gregg S. Spitler Tony O. Greco Robert C. Tripp husband Kurt W. Hillig (PhD 1981, Robert Kuczkowski) spent Colorado College. At the 2012 Colorado College Honors Con- Sheila C. Greenblatt Joesph M. Vanderkelen Robert Kuczkowski Faculty 15 years after graduation in the Chemistry Department at UM Chemistry Department Fund Nick P. Walker Nancy E. Chapel David J. Hart Award vocation he received the Bob Pizzi Outstanding Faculty Advisor Edward P. Washabaugh as a Research Scientist in computational and computer system Steven A. Clarke David P. Hesson Carol A. Fierke of the Year Memorial Award. James K. Watkins support. For the past 16 years he has been a Network Planning Ellene T. Contis Roland F. Hirsch Robert L. Kuczkowski Harriet R. Weinstein Analyst for the UM I.T. Communication Services. Evelyn P. Tyner Shirley M. Hoenigman Christian F. Casper (MS 2001, Dimitri Coucouvanis) completed Jamie A. Wiersema Robert W. Parry Scholarship Susan E. Forest Walter M. Holloway a PhD in 2009 in the interdisciplinary program in Communica- Veronica H. Wiley Gary N. Bokerman Andrew Higgs (PhD 2010, Melanie Sanford) is a Visiting Profes- Joel M. Goldberg Instrumentation Laboratory John P. Wolfe David W. Badger tion, Rhetoric and Digital Media (CRDM) at North Carolina Mark T. Goulet James F. Jackson sor at Washington and Lee University. William D. Wright Karen W. Morse State University. He is now a Lecturer III in the Technical Philip L. Gravel Norman P. Jensen Dorothy T. Wu Robert T. & Bonnie P. Paine Communication Program in the College of Engineering at UM, Kami Hull (PhD 2009, Melanie Sanford) has just started as an Kenneth L. Hall Eric T. Johnson Grace S. Yee Barry P. Hart Robert L. Jones Richard D. Sacks Memorial specializing in chemical, biomedical and aerospace engineering. Assistant Professor of Chemistry at the University of Illinois, Steven R. Zawacky P & G Fund Steven R. Jordan Student Travel Champaign Urbana. James M. Julian Paul F. Zittel Michael D. Morris Heather (Crocker) Clark (BS 1994, PhD 1999, Raoul Kopelman) Walter E. Rupprecht In memory, Prof. Martin Stiles Charles J. Scanio Phyllis W. Karseboom is an Associate Professor in the Department of Pharmaceutical Dipannita Kalyani (PhD 2008, Melanie Sanford) is an Assistant Harold L. Kohn Arthur J. Ashe Peter A.S. Smith Fellowship Suzanne E. Schulz In memory, Theodore Jacob ‘44 David W. Emerson Science at Northeastern University. Dr. Clark’s research focuses Professor of Chemistry at St. Olaf College. She has just been Walter S. Syrkowski Cordelia B. Kohrman Paul M. Kovach Marilyn L. Jacob Douglas M. Kalvin on the development of nanosensors to measure concentrations awarded a PRF starter grant. Chemistry Strategic Fund George I. Fujimoto of ions and small molecules at the cellular level, as well as in Paul E. Krieger Chemistry, Pres Challenge for Kyle Litz (PhD 1998, Mark Banaszak Holl) is the Chief Techni- Bradley J. Adelman Joanne and Jerry Robertson Kevin J. Kubarych Grad Support vivo. Her work has been featured in a live CNN interview, the Mark M. Banaszak-Holl cal Officer of Auterra, Inc of Malta, NY. He has developed a Dominick A. Labianca John J. Callahan Milton Tamres Teaching Award Wall Street Journal, WIRED magazine and the MIT Technology Bart Bartlett new catalyst for desulfurization and oil upgrading of Canadian Robert A. Landowne Robert N. Ceo Marjorie L. Carter Review. In July she received a DARPA Young Faculty Award to BASF Corporation Lisa A. Lanning oil sands. The catalyst has been featured in the Business Review Irving M. Adler develop tools for measuring neurotransmitter release. J. Dolf Bass Ginny S. Lin Graduate Fellowships Funds and CBS Marketwatch. John E. Bauman Richard N. Loeppky Timothy F. Merkel Robert C. Taylor Fund Nicholas Deprez (PhD 2009, Melanie Sanford) has finished a Timothy G. Bee John F. Mahaney In memory, Theodore Jacob Irving M. Adler Costas Lyssiotis (BS, 2004) received his PhD from Scripps Larry G. Bell Virginia A. Dilkes postdoctoral appointment at the ETH in Zurich and has started Jen-Jenliu Mao Marilyn L. Jacob Research Institute in 2010. He is now pursuing postdoctoral Jason A. Berner Jessica M. Marsh Chava B. Kopelman James & Madalene Davis a job at DuPont Agriculture. Robert J. Beuhler Adam J. Matzger Robert T. & Bonnie P. Paine studies as a Damon Runyon Fellow at Harvard Medical School. Graduate Fellowship Fund Neal B. Blatt Eugene W. May David R. Taylor Gerald (Jerry) Fong (PhD 1978, Robert Kuczkowski), Profes- James K. Davis Liz McDowell (PhD (Biophysics) 2008, Nils Walter) has moved Sylvia L. Bone Kelly McDow Werner E. Bachmann Memorial sor of Chemistry at SUNY Alfred State College, has moved this Steven A. Boskovich from Carleton College to a position as Assistant Professor of Kirsten L. McKillop Chemistry Special Scholarships Lecture Fund summer to a newly refurbished building which provides a home William F. Bradford Myrtle S. McLain Physics at Kalamazoo College. Fund Frederick L. Crane Amanda P. Buscetta Shirley A. McLean for the forensic science technology program which he coordinates. Roger W. Blain Robert A. Gregg Jun Pan (PhD 2007, Arthur Ashe) works as a Medicinal Chemist Thomas A. Caughey Anne J. McNeil Dow Corning Corporation John A. Gladysz (BS 1971, Longone, PhD 1974 Stanford) Cengage Learning Merck Company Fdn J. M. Lagowski Novartis Chemical Sciences with Incyte, Wilmington, DE. Qinlin Chang David E. Newton Lectureship Distinguished Professor of Chemistry, Dow Chair in Chemical Mark A. Chidel Edward D. North Robert & Carolyn Buzzard Grad Novartis Institute for BioMedical Innovation and his wife, Professor Janet Bluemel, in the Chemistry Sethu Pitchiayu (PhD 2011, Nils Walter) has published a “top Elna M. Clevenger D. Eugene Overton Chem Student Leadership Research, Inc. Department of Texas A&M University, have made a bequest to download” article in the European Molecular Biology Organi- Joseph S. Cook P & G Fund Robert A. and Carolyn Buzzard the University of Michigan. The multi directed gift will endow a zation (EMBO) reports and continues as a post doctoral in the Dwayne L. Cook Richard A. Pacer Chemistry Dept. - Library Summer Chemistry Scholars Richard J. Bard Marilyn A. Crane Janet P. Padilla chair or professorship for an associate professor in the Chemistry Walter laboratory. Fund Janet C. Haartz Renee I. Cribbins Pfizer Foundation Department in the name of Professor Gladysz’s parents, Edward and J. Dolf Bass Douglas J. Raber (PhD 1968, Richard Lawton) and his wife Linda Robert Damrauer Pharmacia Maria Coward Other Support Margean Gladysz. In addition, funds are provided to support the Colleen M. DeKay Linda K. Phillips have published a new science fiction book, “Face of the Earth.” Norman P. Jensen Dow Chemical Company Fdn research efforts of faculty below full professor, for undergraduate Theodore S. Dibble Eric R. Pohl It is the story about a smallpox outbreak on an Indian reservation Gary R. Kravitz 3M Corporation research efforts and for departmental support without restriction. James E. Dickson John M. Powers in New Mexico and the geopolitical response in Washington. The
10 2012 U-M DEPARTMENT OF CHEMISTRY 11 book is available at barnesandnoble.com. the Immunology section of the Division Freedom,” with Henry Holt Books. It is Robert E. Ireland (Chem. Fac., 1956-65) deo in 1979. Dr. Laborde dedicated his in 1935. At Michigan he wrote his Ph. or www.raberbooks.com. of Infectious Diseases in the Department a story about the underground RR and is died on February 4, 2012 in Sarasota, FL professional life to the discovery of drugs D. thesis on, “The Relative Stabilities of of Medicine, Faculty of Medicine at the intended for middle grade readers. Peggy at the age of 82. for the relief of human suffering. Dr. Aryl Chloro Methanes.” While at Cal.- Manfred T. Reetz (MS 1967, Daniel Imperial College, London. Stiles is a prizewinning author of more than Laborde was employed by Parke-Davis Berkeley he competed in the high jump and Longone) delivered the Werner E. Bach- A native of Cincinnati, Professor Ireland eleven books primarily directed towards (Warner-Lambert), DuPont-Merck Phar- at Michigan he tutored some of Michigan’s mann Lecture on March 27, 2012. Pro- Samer Salamekh (BS 2011),who worked received his AB degree from Amherst Col- young readers. maceuticals and Ariad prior to joining Telik star athletes in chemistry. lege in 1951 and a PhD in chemistry from fessor Reetz was the director of the Max with Professor Ramamoorthy, has coau- (then Terrapin) in Palo Alto. At the time Weihong Tan the University of Wisconsin, Madison in During WW II he was drafted into the US Planck Institute for Kohlenforschung in thored several articles in the past year. (PhD 1993, Raoul Kopel- of his death he was Executive Director of 1954 working with W. S. Johnson. He then Army and was deployed to Dutch Harbor Muelheim, Germany 1991-2010 and has He is currently a medical student at Ohio man) has been named Distinguished Pro- Chemistry at Telik. During his 14 years at spent two years as a post-doctoral fellow in the Aleutian Islands. He then attended recently become the first Hans Meerwein State and has received a Fulbright Fellow- fessor in the Department of Chemistry at Telik Dr. Laborde built the Chemistry De- with W. G. Young at UCLA. OCS in Maryland and became an instruc- Research Professor at the University of ship to pursue research at the Max Planck the University of Florida. He is also the partment and was intimately involved with winner of the 2012 ACS Florida Award tor in the Army Chemical Warfare School. Marburg. He has previously been honored Institute in Leipzig, Germany. In 1956 Ireland joined the chemistry fac- the discovery and development of several by receiving a large number of awards. for Outstanding Contributions to Chemi- Subsequently he was active in the Army Richard W. Shubart (BS 1962) retired ulty at UM where he served until 1965. He clinical candidates in the oncology field. It was our great pleasure to welcome him cal Sciences. Reserve, retiring as a Lieutenant Colonel. from Pfizer (formerly Searle/Monsanto/ then moved to the California Institute of back to the UM to deliver our premier Dr. Laborde is survived by his wife of 31 years, Pharmacia) as Senior Director of Global Salena Whitfield(PhD 2008, Melanie San- Technology where he became a Professor Dr. Reed was hired by Standard Oil Co. lecture. Laura and by daughters Ana and Andrea. R&D Quality Assurance. He enjoys retire- ford) is now a manager in the competitive of Chemistry. In 1985 he became director of California (now Chevron). He worked David Rueda (Postdoctoral 2001-5, Nils ment and does some consulting. diagnostics division of Abbott Diagnostics of the Merrell Dow Research Institute in Richard (Dick) Loeppky (MS 1961, PhD on maximum utilization of refinery stocks Walter) has moved from Wayne State Uni- in Chicago. Strasbourg, France. After one year he 1963, Peter Smith) died on April 21, 2012 which led him into computations and Martha Bennett (Wells) Stiles (BS 1954) versity to a new position as Chair within moved to the University of Virginia, where at the age of 74. computers. He introduced the first modern has published a new book, “Sailing to he was the Thomas Jefferson Professor of computer to Chevron. He retired in 1975. Dick was born in Lewiston, Idaho and Chemistry. He retired in 1995. received his BS in chemistry from the He is survived by his daughter Gwen Lun- In Memoriam From 1951-55 Dr. Horwitz was an As- Professor Ireland was a leading figure in University of Idaho in 1958. During the dmark, his son Dennis, five grandchildren sistant Professor of Chemistry at Illinois synthetic organic chemistry. He is particu- summers he worked in a lumber mill. He and two great-grandchildren. We are saddened to announce the deaths of the following faculty, alumni, alumnae and Institute of Technology. In 1956 he became larly known for his use of the ester enolate recalled that, “The work was hard and Kenneth L. Stevenson (PhD 1968, James friends of the Department. a Researcher at Detroit Institute of Cancer Claisen rearrangement, now known as boring but it paid very well and provided Verdieck) died on February 22, 2012 at Research and a Professor at Wayne State the Ireland-Claisen rearrangement. He for my college education.” In 1959 he the age of 72. Don C. DeJongh (PhD 1962, Michael the US Army having served in both WW Medical School. The Cancer Foundation was recognized by the award of an A.P. came to the UM where he worked with Martin) died in Palo Alto, CA on July II and the Korean War. was renamed the Barbara Ann Karmanos Sloan Fellowship, the ACS Ernest Guen- P.A.S. Smith. He then spent a year as an Dr. Stevenson was born in Fort Wayne, 24, 2011 at the age of 74. Dr. DeJongh Cancer Institute on 1995. He remained Professor Emerson served on the chemis- ther Award in the Chemistry of Natural NIH post-doctoral with Professor Nelson IN. He received a BS in 1961 and an MS received his BA in chemistry from Hope with these institutions the rest of his life. try faculty of UM-Dearborn for 18 years. Products in 1977 and the ACS Award J. Leonard at the U. of Illinois. in 1965 both in chemistry and both from College, MI prior to attending the UM. In 2005 he became Professor Emeritus. He was the dean of the College of Arts, for Creative Work in Synthetic Organic Purdue University prior to his attendance After a year as a postdoctoral fellow with In 1964 he began his independent scien- Science and Letters. In 1981 he moved Dr. Horwitz published more than 100 Chemistry in 1988. at UM. Klaus Biemann at MIT, DeJongh joined tific career at the University of Missouri- to the University of Nevada, Las Vegas articles in peer-reviewed Journals. His the Chemistry Department at Wayne State He is survived by his wife, Margaret and Columbia. After rising through the ranks Dr. Stevenson then joined the chemistry (UNLV) to serve as dean of the College major contribution for which he became University, where he developed a research sons Mark and Richard. The family has from instructor to full professor, he was faculty at Indiana University-Purdue Uni- of Mathematics, Science and Engineering famous was the synthesis of AZT (azido- program examining the mass spectrometry asked that memorial contributions be made named H. G. Schlundt Distinguished versity at Fort Wayne (IPFW). He became (now College of Science). He returned thymidine) in 1964. AZT was originally of organic compounds. From 1972 until to the University of Michigan Chemistry Professor. In 2003 he became Professor a full professor in 1978 and served as the to full-time teaching in 1989 and retired prepared as an anti-cancer drug for which 1978 he was a professor of chemistry at Fund (Fund #791235) Emeritus and was also a Visiting Scholar chairman of the chemistry department in 1998. it was ineffective. In the mid 1980s Bur- in the Department of Medicinal Chemistry from 1979 to 2003. He did research in the the University of Montreal. Leroy O. (Lee) Krbechek (PhD 1961, roughs Welcome (now Glaxo Smith Kline) at the University of Washington, Seattle, area of photochemistry and published more Professor Emerson received the Donna Peter Smith) died in Salinas, CA on De- He then founded the Finnigan MAT Insti- patented AZT which became the first where he had relocated after retirement. than 50 articles in peer-reviewed journals. Weistrop Career Achievement Award from cember 13, 2011 at the age of 77. tute in Cincinnati, OH where he served as drug used to treat AIDS. Unfortunately He was recognized as Chemist of the Year UNLV in 2009. The Emerson Medal, at Dick’s research involved chemical toxicol- president until 1984, when he moved to Dr. Horwitz received no financial benefit Born in Goodridge, MN, Krbechek did in 1979 and 1993 by the ACS Northeastern UNLV is named in his honor. ogy with special interest in carcinogenesis the Finnigan headquarters in San Jose, CA, from his discovery. He had also prepared graduate work with Professor P.A.S. Smith Indiana Section and Researcher of the Year by N-nitroso compounds. He was named as market manager and customer service Professor Emerson is survived by his several other compounds which have been at UM, receiving his PhD in 1961. Dr. by the IPFW Sigma Xi chapter in 1994. one of the inaugural Fellows of the ACS manager. In 1990 he managed the Mid- wife of 57 years, Shirley, sons Richard widely used in anti-AIDS therapy. Krbechek worked for the Henkel Corpora- in 2009. He received the ACS Division of Dr. Stevenson is survived by his wife Pacific Laboratory in Mountain View, CA and Eric and daughter Ellen and seven tion. He held more than fifty patents and He received numerous awards. Among Chemical Toxicology Founders’ Award in Carmen, daughters Mindy Grewar, Jill until his retirement in 1995. grandchildren. had published twelve journal articles in them are: Honorary D. Sc., University of 2010 and was inducted into the University Paulik and Sarah Stevenson and three the area of organic chemistry. Dr. DeJongh is survived by his wife of 51 Jerome P. Horwitz (PhD 1950, Peter Detroit (1987), Michigan Scientist of the of Idaho Hall of Fame in 2011. grandchildren. His first wife Virginia years, Miriam, sons, Fritz and Matt and Smith, Post-doctoral 1951, Werner Bach- Year (1983), Outstanding Achievement Dr. Krbechek is survived by his wife died in 1991. He is survived by his daughter Ann daughter Katie as well as six grandchildren. mann) died in Bloomfield Township, MI Award in recognition of the synthesis of Blanche, sons Randy and John and a num- on September 6, 2012 at the age of 93. AZT by the University of Michigan, and Loeppky-Finn and son Greg Loeppky and Florence (Barr) Westrum, wife of David W. Emerson (MS 1954, PhD 1958, ber of extended family members. the Distinguished Service Award by Wayne two granddaughters. Professor Emeritus Edgar Westrum, died Peter Smith) died in Las Vegas, NV on Dr. Horwitz was born in Detroit. He ob- Edgardo Laborde (PhD 1984, Joseph Ma- on August 6, 2012 at the age of 91. The State University (1995). Eugene B. Reed (PhD 1939, Joseph Hal- January 12, 2012 at the age of 83. Profes- tained his BS in 1942 and MS in 1944 in rino) died in Palo Alto, CA on September Westrums had been married for 69 years. ford) died at his home in Pleasant Hill, CA sor Emerson was born in Littleton, MA. chemistry from the University of Detroit. Dr. Horwitz is survived by his wife of 61 27, 2011 at the age of 59. She is survived by Edgar and their four on May 10, 2012 at the age of 98. He received his AB in chemistry from At the UM he received his PhD in 1950 years, Sharon, two daughters, Carol Kastan children, six grandchildren and four great- He was born in Rosario, Uruguay and Dartmouth College in 1952. At Michigan working with P. A. S. Smith. He then and Suzanne Gross and five grandchildren. Dr. Reed was born in Chico, CA and grandchildren. obtained his BS in Pharmacy from the he received his PhD in 1958 working with spent a year as a Parke Davis Fellow with received his BS from U. Cal.-Berkeley P.A.S. Smith. Emerson was a veteran of Werner Bachmann. Universidad de la Republica in Montevi-
12 2012 U-M DEPARTMENT OF CHEMISTRY 13 Robert T. Kennedy, Hobart H. Willard Collegiate Vincent L. Pecoraro, John T. Groves Collegiate Alumni-Alumnae Reply Form Please complete and return this form for our alumni files; include news of your current activities Faculty Professor of Chemistry; Professor, Pharmacol- Professor of Chemistry. Synthetic Inorganic or suggestions for the next Newsletter: ogy. Analytical Chemistry. and Bioinorganic Chemistry. Hashim M. Al-Hashimi, J. Lawrence Oncley Nancy K. Kerner, Lecturer IV. Chemical Edu- James E. Penner-Hahn, Professor of Chemis- Name ______Name of Spouse ______Collegiate Professor of Chemistry and Bio- cation, Learning and Instructional Methods. try; Professor, Biophysics. Associate Dean, University______Degree______Year_____ Advisor______Chemical physics; Professor, Biophysics. Raoul Kopelman, Richard Smalley University LSA. Biophysical Chemistry and Inorganic Biology. University______Degree______Year_____ Advisor______Professor of Chemistry; Professor, Biomedical Spectroscopy. Philip Andrews, Professor of Biological Chem- Engineering; Professor, Physics. Analytical/ A. Ramamoorthy, Professor of Chemistry; Residence Address ______Home Phone ______istry, Chemistry, Comp Med & Biology, Physical/Biophysical Chemistry. Professor, Biophysics. Structural Studies of City, State, Zip ______Medical School and Director MLSC-Core Masato Koreeda, Professor of Chemistry; Biological Molecules. Bioana- Tech Alliance Proteomics Center. Professor, Medicinal Chemistry. Synthesis Brandon Ruotolo, Assistant Professor of Chem- Firm/Institution______Position ______lytical Chemistry of Natural Products, Small Molecule-DNA istry. Analytical Chemistry. Mark M. Banaszak Holl Business Address ______Business Phone ______, Professor of Chem- Interaction, Chemical Carcinogenesis, Gly- Melanie Sanford, Moses Gomberg Collegiate istry; Professor, Macromolecular Science & cobiology. Professor of Chemistry, Arthur F. Thurnau City, State, Zip ______E-mail ______Engineering, Professor Biomedical Engineer- Kevin Kubarych, Associate Professor of Chem- Professor of Chemistry, Organometallic Synthetic and Mechanistic Solution, NEWS ABOUT YOURSELF: (Unless you request otherwise, we will feel free to mention any of this in future Newsletters) ing. istry. Physical and Biophysical Chemistry. Chemistry. Surface, and Solid State Chemistry. Kenichi Kuroda, Assistant Professor of Dentist- Roseanne J. Sension, Professor of Chemistry; I do NOT wish to have my news in the Newsletter. Bart M. Bartlett , Assistant Professor of Chem- ry, Biologic & Materials Sciences, Biomedical Professor of Physics. Physical Chemistry, Inorganic, Materials Chemistry. istry. Engr, and Chemistry. Physical Chemistry. Ultrafast Laser Spectroscopy. Julie S. Biteen , Assistant Professor of Chemistry. Nicolai Lehnert, Associate Professor of Chem- David H. Sherman, Hans W. Vahlteich Professor Physical and Biophysical Chemistry istry. Bioinorganic Chemistry, Physical of Medicinal Chemistry; Professor, Microbiol- Charles L. Brooks III, Warner-Lambert/Parke- Inorganic Chemistry. ogy and Immunology; Professor, Chemistry;
Davis Professor of Chemistry and Biophysics. Mi Hee Lim, Assistant Professor of Chemistry; Research Professor, Life Sciences Institute. Physical Chemistry/Biophysical Chemistry/ Research Assistant Professor, Life Sciences Medicinal Chemistry. Theoretical and Computational Chemistry Institute. Bioinorganic, Medicinal Chemistry, Jadwiga Sipowska, Lecturer IV. General and Biophysics. Chemical Biology. Chemistry. Heather A. Carlson, Professor of Medicinal David M. Lubman, Maude T. Lane Professor Matthew Soellner, Assistant Professor of Me- Computa- Chemistry; Professor, Chemistry. of Surgical Immunology; Professor, Surgery; dicinal Chemistry; Assistant Professor of tional Chemistry, Drug Design, Theoretical Pathology; Professor, Chemistry. Biologi- Chemistry. Bioorganic Chemistry, Chemical Biophysics. cal Mass Spectrometry, Spectroscopy and Biology, Organic Chemistry. Mary Anne Carroll, Professor of Atmospheric, Instrumentation. Nathaniel Szymczak, Dow Corning Assistant Oceanic and Space Sciences; Professor, Stephen Maldonado, Assistant Professor of Professor of Chemistry. Energy Science, Atmospheric Chemistry. Address corrections should be directed to UM Alumni Office website at http://alumni.umich.edu/ Chemistry. Chemistry. Electrochemistry, Materials Inorganic Chemistry. Personal updates can be sent to: University of Michigan, Chemistry Alumni Office, Department of Chemistry Zhan Chen, Professor of Chemistry; Professor, Chemistry. Nils G. Walter, Professor of Chemistry. Chemi- 930 N. University Ave., Ann Arbor, MI 48109-1055; E-mail: [email protected] Macromolecular Science & Engineering. Anna K. Mapp, Professor of Chemistry; Profes- cal Biology. Biomaterial and Polymer Surface, Biocom- Chemistry Web Address: http://www.umich.edu/~michchem sor, Medicinal Chemistry. Organic Chemistry, patibility. John P. Wolfe, Professor of Chemistry. Associate Chemical Biology, New Synthetic Methods. Chair for Undergraduate Education. Organo- Mary Sue Coleman , UM President and Profes- E. Neil G. Marsh, Professor of Chemistry; metallic Chemistry. sor of Chemistry. Professor, Biological Chemistry. Chemical Ronald W. Woodard, Frederick F. Blicke Col- Brian Larsen, John Brian P. Coppola , Arthur F. Thurnau Professor Biology, Enzymes, Structure, Mechanism legiate Professor of Medicinal Chemistry; Montgomery and of Chemistry; Associate Chair for Educational and Specificity; Protein Engineering and Professor, Chemistry. Medicinal Chemistry. Peter A. S. Smith Development and Practice in Chemistry. Molecular Recognition. Organic Chemistry, Science Learning and Edward T. Zellers, Professor of Environmental Brent R. Martin, Assistant Professor of Chem- Instructional Methods. and Industrial Health; Professor, Chemistry. istry. Bioanalytical Chemistry. Environmental-Analytical Chemistry. Carol A. Fierke, Chair. Jerome and Isabella Adam J. Matzger, Professor of Chemistry; Pro- Dominika Zgid, Assistant Professor of Chem- Karle Collegiate Professor of Chemistry; fessor, Macromolecular Science & Engineer- Chemical istry. Computational Chemistry, Inorganic Professor, Biological Chemistry. ing. Organic, Polymers/Organic Materials. Biology, Bioinorganic Chemistry. Chemistry. Anne J. McNeil, Seyhan N. Ege Assistant Pro- Anthony H. Francis, Arthur F. Thurnau Profes- Paul Zimmerman, Assistant Professor of fessor of Chemistry. Polymer and Organic/ Chemistry. Physical Chemistry, Theoreti- sor of Chemistry; Associate Dean, LS&A. Materials Chemistry. Magnetic Resonance, Vibrational and Elec- cal Chemistry. tronic Spectroscopy of Materials. Mark E. Meyerhoff, Philip J. Elving Collegiate Professor of Chemistry. Bioanalytical Chem- Eitan Geva, Professor of Chemistry. Theoretical istry, Electrochemical and Optical Sensors. and Computational Chemistry. Professors Emeriti: Arthur J. Ashe III, John Montgomery, Professor of Chemistry. Lawrence S. Bartell, S.M. Blinder, Dimitri Incoming Graduate Class of 2012 Gary D. Glick, Werner E. Bachmann Collegiate Organic and Organometallic Chemistry. Professor of Chemistry; Professor, Biological Coucouvanis, James K. Coward, M. David Chemistry. Chemical Biology, Bioorganic Michael D. Morris, Richard D. Sacks Collegiate Curtis, Thomas M. Dunn, B.J. Evans, Chemistry, Molecular Recognition. Professor of Chemistry. Analytical Laser John L. Gland, Henry C. Griffin, Robert Spectroscopy and Imaging; Electrophoretic L. Kuczkowski, Richard G. Lawton, Law- Theodore Goodson, III , Richard Barry Bernstein Separations. rence L. Lohr, Daniel T. Longone, Joseph Collegiate Professor of Chemistry; Professor, P. Marino, Christer E. Nordman, Paul G. Macromolecular Science & Engineering. Pavel Nagorny, Robert A. Gregg Assistant Professor of Chemistry. Organic Chemistry. Rasmussen, Robert R. Sharp, Peter A.S. Physical Chemistry. Smith, Leroy B. Townsend, Edwin Vedejs, Amy Gottfried, Lecturer IV. Kathleen V. Nolta, Lecturer IV. Organic Bio- chemistry. Edgar F. Westrum, Jr., John R. Wiseman, Vaughan poster session Kristina Hakansson, Associate Professor of Charles F. Yocum Chemistry. Analytical Chemistry. Ice cream social
14 2012 University of Michigan Department of Chemistry NON-PROFIT ORGANIZATION 930 N University US POSTAGE Ann Arbor MI 48109-1055 PAID ANN ARBOR, MI PERMIT #144 Address Service Requested
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