DOCSLIB.ORG

AKNE (Acne Vulgaris )

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
AKNE (Acne Vulgaris ) AKNE (acne vulgaris) - PRISTUP U OOM - prevalencija kod adolescenata do 95%, najčešće 13 - 15 g., ranije kod djevojčica, nakon 20. g. se obično povlače, no mogu potrajati i nakon 30. g. (češće kod Ž), teži oblici češće kod M - kronična upala kože, zahvaća pilosebacealnu jedinicu (dlaka sa ovojnicama, mišić podizač dlake i lojna žlijezda), najčešće na licu (99%), rjeđe leđa (60%) te prsa (15%) ETIOLOGIJA - nasljeđe, hormoni i bakterije - nasljeđivanje AD (veličina lojnica i osjetljivost na podražaje → luče više loja → glavni preduvjet za razvoj akni) - pubertet - poremećen odnos spolnih hormona (↑androgena ili ↓estrogena) → hipertrofija i hiperfunkcija lojnica → više loja → folikularna hiperkeratoza → pilosebacealne jedinice začepe se lojem i odljuštenim keratinocitima → komedon - otvoreni (otvor folikula širok → crna točkica) ili zatvoreni (otvor nije vidljiv, sitne polukuglaste bjelkaste tvorbe) - endokrinološka i gin obrada kod žena samo u slučaju drugih znakova hiperandrogenizma (hirzutizam, poremečaj ciklusa, neplodnost.. → PCOS) ili preuranjenog puberteta - komedoni se ponekad koloniziraju normalnim anaerobom kože Propionibacterium acnes → upala → papula, pustula, apscedirajući čvorovi KLINIČKI OBLICI: 1) ACNE COMEDONICA - blagi oblik - promjene opipljive, promjer 1-3 mm - otvoreni i zatvoreni komedoni - može biti prisutna i max 1 papula 2) ACNE PAPULOPUSTULOSA - umjereno težak oblik akni - papule i pustule 2-5 mm, pustule površnije, papule kod dublje upale (češće leđa i sternalno) - BLAGI oblik → komedoni, do max 5 papula/pustula UMJERENI oblik → komedoni, do max 20 papula/pustula, max 1 nodul TEŠKI oblik → veliki broj komedona, >20 papula/pustula, pokoji nodul 3) ACNE CONGLOBATA (NODULARNE AKNE) - najteži oblik, češće kod mladića, upala zahvaća dublje dijelove folikula → tvrdi, bolni čvorovi (noduli >5mm, veliki noduli >1cm) koji često konfluiraju i stvaraju pločaste, tvrde, crvenkasto- plavkasto izbočene infiltrate → „omekšanjem“ nastaje šupljina s gnojnim sadržajem, koji se fistulom izlučuje na površinu Drugi oblici akni: acne neonatorum: komedoni na obrazima i bradi dojenčadi (zbog majčinih hormona) acne menstruationis: premenstrualno zbog hormonskih promjena; liječenje prema kliničkom obliku acne inversa - Hidradenitis suppurativa acne fulminans: češće kod M, nagla pojava acne conglobata s hemoragičnim krastama na licu, vratu, prsima i leđima uz ↑temp, artralgije, ↑SE, ↑L; terapija - izotretinoin i kortikosteroidi Dif.dg: rosacea (nema komedona, izražen eritem i teleangiektazije) acne medicamentosa - npr. kortikosteroidi (nema komedona, pustule sve u istom razvojnom stadiju, terapija je uklanjanje lijeka) perioralni dermatitis (nema komedona, izražen eritem, najčešće samo oko usta) LIJEČENJE - redovito čišćenje kože (preparati za njegu kože sklone aknama, npr. Effaclar, La Roche- Posay...) uz lokalnu keratoličku ili antimikrobnu terapiju, a najčešće u kombinaciji → uklanjanjem viška lipida sprečavaju začepljenje otvora folikula i stvaranje novih komedona - nanose se na čistu i suhu kožu, ne samo na dio koji trenutno ima akne, već i tamo gdje se inače javljaju - ne smiju <12g, na oštećenu ili ekcematoznu kožu, niti na kožu s opeklinama od sunca - nuspojave svih su suhoća, iritacija, osjećaj žarenja, napetosti kože, eritem, ljuštenje, svrbež → prorijediti primjenu ili ukinuti; često je na početku primjene iritacija jača, može se nanijeti hidratantna krema par minuta nakon lijeka, ili isprati lijek nakon par sati u prvim tj dok se koža ne privikne - nakon povlačenja akni ostavlja se terapija održavanja (primjena 2xtj). Tijekom primjene svih preparata (lokalno i sistemski) preporuča se izbjegavati izlaganje suncu te koristiti sredstvo za zaštitu od sunca s visokim zaštitnim faktorom! AKNE KOMEDOGENE PAPULOPUSTULOZNE NODULARNE BLAGE/UMJERENE TEŠKE topički retinoid BP/adapalen Sustavni retinoid - izotretionin (Roaccutane) adapalen (Sona) ILI ILI BP/klindamicin BP/adapalen + doksiciklin +/- OHK (Diane-35) benzoil peroksid (Dercome Clear) BP/adapalen Procjena učinka nakon 4 tj → ILI +klindamicin nezadovoljavajuće → idući (Aknet) korak, zadovoljavajuće azelatna kiselina nastavak liječenja uobičajeno (Skinoren) kroz 3 mj; nakon povlačenja ostavljamo topički pripravak na dozi održavanja (2xtj) BP/adapalen BP/adapalen + (Epiduo) doksiciklin* DERMATOLOGU ILI 1x100mg BP/klindamicin (Duac) - može se kombinirati i druge keratolitike, ali ne preporučuje se monoterapija klindamicinom lokalno (Aknet), kao ni kombinacija oralnih i topičkih antibiotika zbog razvoja rezistencije - kod komedogenih akni ne preporučuje se primjena sustavne terapije (retinoidi, hormoni, antibiotici) - najučinkovitiji antibiotik - doksiciklin, kod nepodnošenja azitromicin; liječenje max 3 mj - u američkim smjernicama opcija i spironolakton kod žena - ima antiandrogeni učinak, ↓proizvodnju testosterona i kompetitivno blokira androgene receptore Domena liječenja SOM-a su komedogene akne te blagi do umjereni oblik papulopustoloznih akni, u slučaju neuspjeha kod uključivanja sistemske terapije upućujemo dermatologu (Amb za kozmetologiju)! Adapalen (Sona 1 mg/1 g gel ili krema) - 1x navečer (kod dobre tolerancije može i 2x) - procjena učinka terapije nakon 3 mj - kontraindikacije: trudnoća, kod žena koje planiraju trudnoću Benzoil peroksid (Dercome Clear 40 mg/g suspenzija za kožu) - 2x/d (kod osjetljivije kože svaki 2.dan tijekom 1.tj, a zatim 1x/d), lagano se utrlja u vlažnu kožu, a nakon 2 min se pjena ispere vodom - primjena prosječno 4-12 tj Azelatna kiselina (Skinoren 200 mg/g krema) - 2x dnevno - poboljšanje treba biti vidljivo nakon 4 tj, a primjena min 3 mj BP + adapalen (Epiduo 1 mg/g + 25 mg/g gel) - 1x dnevno navečer - poboljšanje za 1-4 tj, a ukupno trajanje liječenja ovisi o kliničkom stanju - kontraindikacije: <9g BP + klindamicin (Duac 10 mg/g + 50 mg/g gel) - 1x navečer - učinak nakon 2-5 tj, koristi se kontinuirano do 12 tj Doksiciklin 100 mg - 1x1/d, sa 100 ml vode te min 1h prije lijeganja; kod dispepsije može s mlijekom ili hranom - trajanje liječenja - max 3 mj (po zimi zbog fotoosjetljivosti → liječenje se prekida pri prvoj pojavi kožnih problema ili eritema!) -nakon prvih mj dana doza se može reducirati - kontraindikacije: <50kg, trudnoća i dojenje (učinak na zube i razvoj koštanog sustava) Azitromicin 500mg - terapija kod nepodnošenja doksiciklina -1x 500 mg/3 dana u 1. tj, nastavak uzimanja 1x500 mg 1xtj/9 tj (4 kutije) Hormonski kontraceptiv - ciproteronacetat/etinilestradiol (Diane-35 tbl) - uvođenje i praćenje u domeni dermatologa i ginekologa - 1x1 tbl od 1.dana krvarenja tijekom 21 dan, 7 dana pauza pa ponavljanje - procjena učinka nakon min 2 mj, duljina liječenja u dogovoru s dermatologom - kontraindikacije: osobna ili obiteljska anamneza tromboembolije, primjena drugog hormonskog kontraceptiva, čimbenici KV rizika (DM, hipertenzija, HLP, pušenje)… - nuspojave: mučnina, bol u abdomenu, povećanje TT, glavobolja, promjene raspoloženja, osjetljivost dojki, intermenstrualno krvarenje Sustavni retinoid - izotretinoin (Roaccutane caps. à 10 mg) - uvođenje i praćenje terapije u domeni dermatologa - kapsule se uzimanju s hranom, 1-2x dnevno - preporučena početna doza je 0,5 mg/kg dnevno (kasnije prilagodba 0,5 - 1,0 mg/kg) → trajanje od 16-24 tj - kontraindikacije: alergija na kikiriki ili soju, trudnoća/dojenje (potpisuju da će koristiti kontracepciju prije, tijekom i nakon liječenja zbog teratogenosti), bolesti jetre, hiperlipidemija, hipervitaminoza A, istodobno liječenje tetraciklinima - brojne nuspojave → pogoršanje psihičkih tegoba, teške kožne reakcije, teške alergijske reakcije, upalne bolesti crijeva, suhoća oka, oslabljen noćni vid, suha koža, benigna intrakranijalna hipertenzija, ↑ jetrenih enzima, ↑lipida, ↑GUK-a - oprez nuspojave - RIJETKO oslabljen noćni vid, VRLO RIJETKO pospanost, omaglica i smetnje vida - POTREBNO PACIJENTA UPOZORITI kod upravljanja vozilima ili strojevima! - prati se razina transaminaza, kolesterola i triglicerida na početku liječenja, nakon 1 mj, zatim svaka 3 mj (ne savjetuje se određivanje ostalih parametara - u praksi često KKS, GUK) Prehrana - istraživanja povezuju akne i prehranu s visokim glikemijskim indeksom te mliječnim proizvodima, ali smjernice su bez preporuka Autor: Tamara Fable ([email protected]) Adrijana Tomas ([email protected]) https://onlinelibrary.wiley.com/doi/pdf/10.1111/jdv.13776 https://www.jaad.org /article/S0190-9622(15)02614-6/fulltext https://www.cmaj.ca/content/ 188/2/118 https://www.uptodate.com/contents/treatment-of-acne- vulgaris?search=acne&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1 Stanić J, Pintarić Japec V, Soldo D. Mogućnosti i ograničenja liječenja akni u obiteljskoj medicini. Zbornik radova XVII. kongresa HDOD-HLZ. Opatija: HDOD-HLZ; 2017. https://hrcak.srce.hr/60292 https://hrcak.srce.hr/23313 Lipozenčić J i sur. Dermatologija: Bolesti lojnica i folikula dlaka. Zagreb: Medicinska naklada; 2008. http://www.msd-prirucnici.placebo.hr/msd-prirucnik/dermatologija/akne-i-srodni-poremecaji /acne- vulgaris https://www.racgp.org.au/afp/2017/december/acne-in-adolescents/ https://bpac.org.nz/BPJ/2013/March/managing-acne.aspx https://www.icgp.ie/go/library/catalogue/item?spId=075F2D43-5E47-4450-AC4385ACFDC10F C4 https://www.ebm-guidelines.com/dtk/ebmg/home https://emedicine.medscape.com/article/1069804-overview https://www.dermnetnz.org/search.html?q=ACNE https://www.shutterstock.com/search/acne+comedonica https://deximed.de/home/b/haut/illustrationen/dermnet/akne-papulopustuloes/.
Load more

Recommended publications
  • International Journal of Scientific Research
    ORIGINAL RESEARCH PAPER Volume-9 | Issue-1 | January-2020 | PRINT ISSN No. 2277 - 8179 | DOI : 10.36106/ijsr INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH TYPES AND VARIANTS OF ACNE Dermatology Shailee Patel ABSTRACT Acne occur when pores of skin are blocked with oil, dead skin, or bacteria. It can occur when excessive oil is produced by follicles, bacteria build up in pores, and dead skin cells accumulate in pores. All these problem contribute in development of pimple. Acne are majorly seen among teenagers but they can also occur in adults. There are varying from of acne, and their varying treatment. KEYWORDS 1.INTRODUCTION ulcerative colitis and Crohn's disease and syndromes, such as Acne is linked to the change in hormone level during puberty. Acne is a synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) and disorder that is seen worldwide. Acne is a disease of the teenagers but pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) can be seen even in newborn children and also adults. Age and gender syndromes. also play a very important role in onset of acne. Acne most commonly occur between the ages of 10-13 years. Girls have an earlier onset 3.4 Occupational Acne which easily contribute to the onset of puberty in girls than in boys. The Occupational acne is defined as development of acne-like lesions after disease severity in more in boys during the late adolescence. Acne exposure to occupational agents in persons not prone to develop acne mostly develops on areas of skin that have abundant oil glands, like the and who have not had acne before engaging in the said occupation.
    [Show full text]
  • Revista6vol88ingles Layout 1 1/2/14 11:39 AM Página 1039 Página AM 11:39 1/2/14 1 Revista6vol88ingles Layout Revista6vol88ingles Layout 1 1/2/14 11:39 AM Página 1040
    Revista6Vol88ingles_Layout 1 1/2/14 11:39 AM Página 1039 ICONOGRAPHY 1039 s Drug-induced acne and rose pearl: similarities* Acne medicamentosa e a pérola rosa: semelhanças Rubens Pontello Junior 1 Rogerio Nabor Kondo 2 DOI: http://dx.doi.org/10.1590/abd1806-4841.20132586 Abstract: Drug-induced acne is a common skin condition whose classic symptoms can be similar to a rose pearl, as in the case of a male patient presenting with this condition after excessive use of a cream containing corticos- teroids. Keywords: Acneiform eruptions; Drug eruptions; Skin diseases Resumo: A acne medicamentosa é uma dermatose comum, que pode apresentar no seu quadro clássico seme- lhanças à pérola rosa, como no caso apresentado de um paciente do sexo masculino cujo quadro surgiu após uso intempestivo de creme contendo corticoesteróide. Palavras-chave: Dermatopatias; Erupção por droga; Erupções acneiformes Drug-induced acne, or drug-induced acneiform Discontinuation of the drug leads to remission eruption, is an adverse effect of a series of systemic of symptoms. Antihistamines are recommended in drugs, such as corticosteroids, lithium, vitamin B12, case of pruritus, and oral antibiotics are recommend- thyroid hormones, halogen compounds (iodine, ed in case of secondary infection with pustules or 2,3 bromine, fluorine, and chlorine), antibiotics (tetracy- impetiginization. cline and streptomycin), antituberculosis drugs We can observe the usual aspect of a papular (INH), lithium carbonate, antiepileptic drugs (pheno- follicular eruption and, on closer look, a small papule barbital and hydantoin derivatives), cyclosporin A, carefully surmounted by a pustule, which might be a antimycotics, gold salts, isotretinoin, clofazimine, epi- possible evolution into a vesiculopustule, as cited in dermal growth factor receptor inhibitors (cetuximab, the literature, demonstrating the inexorable aspect of gefitinib, and erlotinib), and interferon-beta.1,2 Usually, drug-induced acne (Figure 1).
    [Show full text]
  • Acneiform Dermatoses
    Dermatology 1998;196:102–107 G. Plewig T. Jansen Acneiform Dermatoses Department of Dermatology, Ludwig Maximilians University of Munich, Germany Key Words Abstract Acneiform dermatoses Acneiform dermatoses are follicular eruptions. The initial lesion is inflamma- Drug-induced acne tory, usually a papule or pustule. Comedones are later secondary lesions, a Bodybuilding acne sequel to encapsulation and healing of the primary abscess. The earliest histo- Gram-negative folliculitis logical event is spongiosis, followed by a break in the follicular epithelium. The Acne necrotica spilled follicular contents provokes a nonspecific lymphocytic and neutrophilic Acne aestivalis infiltrate. Acneiform eruptions are almost always drug induced. Important clues are sudden onset within days, widespread involvement, unusual locations (fore- arm, buttocks), occurrence beyond acne age, monomorphous lesions, sometimes signs of systemic drug toxicity with fever and malaise, clearing of inflammatory lesions after the drug is stopped, sometimes leaving secondary comedones. Other cutaneous eruptions that may superficially resemble acne vulgaris but that are not thought to be related to it etiologically are due to infection (e.g. gram- negative folliculitis) or unknown causes (e.g. acne necrotica or acne aestivalis). oooooooooooooooooooo Introduction matory (acne medicamentosa) [1]. The diagnosis of an ac- neiform eruption should be considered if the lesions are The term ‘acneiform’ refers to conditions which super- seen in an unusual localization for acne, e.g. involvement of ficially resemble acne vulgaris but are not thought to be re- distal parts of the extremities (table 1). In contrast to acne lated to it etiologically. vulgaris, which always begins with faulty keratinization Acneiform eruptions are follicular reactions beginning in the infundibula (microcomedones), comedones are usu- with an inflammatory lesion, usually a papule or pustule.
    [Show full text]
  • Drug-Induced Acneform Eruptions: Definitions and Causes Saira Momin, DO; Aaron Peterson, DO; James Q
    REVIEW Drug-Induced Acneform Eruptions: Definitions and Causes Saira Momin, DO; Aaron Peterson, DO; James Q. Del Rosso, DO Several drugs are capable of producing eruptions that may simulate acne vulgaris, clinically, histologi- cally, or both. These include corticosteroids, epidermal growth factor receptor inhibitors, cyclosporine, anabolic steroids, danazol, anticonvulsants, amineptine, lithium, isotretinoin, antituberculosis drugs, quinidine, azathioprine, infliximab, and testosterone. In some cases, the eruption is clinically and his- tologically similar to acne vulgaris; in other cases, the eruption is clinically suggestive of acne vulgaris without histologic information, and in still others, despite some clinical resemblance, histology is not consistent with acne vulgaris.COS DERM rugs are a relatively common cause of involvement; and clearing of lesions when the drug eruptions that may resemble acne clini- is discontinued.1 cally, histologically,Do or both.Not With acne Copy vulgaris, the primary lesion is com- CORTICOSTEROIDS edonal, secondary to ductal hypercor- It has been well documented that high levels of systemic Dnification, with inflammation leading to formation of corticosteroid exposure may induce or exacerbate acne, papules and pustules. In drug-induced acne eruptions, as evidenced by common occurrence in patients with the initial lesion has been reported to be inflammatory Cushing disease.2 Systemic corticosteroid therapy, and, with comedones occurring secondarily. In some cases in some cases, exposure to inhaled or topical corticoste- where biopsies were obtained, the earliest histologic roids are recognized to induce monomorphic acneform observation is spongiosis, followed by lymphocytic and lesions.2-4 Corticosteroid-induced acne consists predomi- neutrophilic infiltrate. Important clues to drug-induced nantly of inflammatory papules and pustules that are acne are unusual lesion distribution; monomorphic small and uniform in size (monomorphic), with few or lesions; occurrence beyond the usual age distribution no comedones.
    [Show full text]
  • Download Your Ultimate Guide to Treat Acne
    Your Ultimate Guide to treating acne FIND OUT The many factors that may be impacting your acne, the types of acne and treatments and products available for managing this common condition. Beat the blackheads Can blackheads be managed at home with JUST skincare? Skip to page xx to find out Contents PAGE NUMBER What is acne? Types of acne Types of acne lesions Grades of acne Causes of acne Common skincare mistakes What skincare should you use? The best treatments for treating acne (INC IV DRIPS, CLEARSKIN, PEELS, NEEDLING, CLEARLIFT, INFINI) Maintaining acne-prone skin Solutions for acne scarring W W W . E D G B A S T O N W E L L N E S S . C O . U K What is acne? Acne is the most common skin disease in adolescence and is just as problematic amongst adults. Acne causes skin various skin lesions and inflammation on the face and body, can appear in waves or as a constant manifestation. More than 90% of the global world population are said to be affected by acne at some point in their lives. Acne is most commonly found on the face, back & chest About 60% of people with adult acne turn to non-prescription treatments to improve the condition. Depending on a number of factors, acne can also cause skin scarring and have a negative psychological impact too. Research tells us that acne can impact our self esteem and image, and increase risk of depression and anxiety. W W W . E D G B A S T O N W E L L N E S S .
    [Show full text]
  • Clinical Dermatology
    CLINICAL DERMATOLOGY A Manual of Differential Diagnosis Third Edition By Stanferd L. Kusch, MD Compliments of: www.taropharma.com Copyright © 1979 (original edition) by Stanferd L. Kusch, MD Second Edition 1987 Third Edition 2003 All rights reserved. No part of the contents of this book may be reproduced or transmitted in any form or by any means, including photocopying, without the written permission of the copyright owner. NOTICE Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The author and the publisher of this work have checked with sources believed to be reliable in their efforts to pro- vide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the author nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or com- plete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information here- in with other sources. For example and in particular, readers are advised to check the product information sheet included in the pack- age of each drug they plan to administer to be certain that the infor- mation contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration.
    [Show full text]
  • Acneiform Dermatoses
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Universität München: Elektronischen Publikationen Dermatology 1998;196:102–107 G. Plewig T. Jansen Acneiform Dermatoses Department of Dermatology, Ludwig Maximilians University of Munich, Germany Key Words Abstract Acneiform dermatoses Acneiform dermatoses are follicular eruptions. The initial lesion is inflamma- Drug-induced acne tory, usually a papule or pustule. Comedones are later secondary lesions, a Bodybuilding acne sequel to encapsulation and healing of the primary abscess. The earliest histo- Gram-negative folliculitis logical event is spongiosis, followed by a break in the follicular epithelium. The Acne necrotica spilled follicular contents provokes a nonspecific lymphocytic and neutrophilic Acne aestivalis infiltrate. Acneiform eruptions are almost always drug induced. Important clues are sudden onset within days, widespread involvement, unusual locations (fore- arm, buttocks), occurrence beyond acne age, monomorphous lesions, sometimes signs of systemic drug toxicity with fever and malaise, clearing of inflammatory lesions after the drug is stopped, sometimes leaving secondary comedones. Other cutaneous eruptions that may superficially resemble acne vulgaris but that are not thought to be related to it etiologically are due to infection (e.g. gram- negative folliculitis) or unknown causes (e.g. acne necrotica or acne aestivalis). oooooooooooooooooooo Introduction matory (acne medicamentosa) [1]. The diagnosis of an ac- neiform eruption should be considered if the lesions are The term ‘acneiform’ refers to conditions which super- seen in an unusual localization for acne, e.g. involvement of ficially resemble acne vulgaris but are not thought to be re- distal parts of the extremities (table 1).
    [Show full text]
  • Program Mounts Bay Road, Perth, Western Australia 49Th Annual Scientific Meeting Perth Convention Andexhibitioncentre, Saturday 14May to Tuesday 17May 2016
    PROGRAM 49TH ANNUAL SCIENTIFIC MEETING PERTH CONVENTION AND EXHIBITION CENTRE, MOUNTS BAY ROAD, PERTH, WESTERN AUSTRALIA SATURDAY 14 MAY TO TUESDAY 17 MAY 2016 AUSTRALIAN DERMATOLOGY NURSES’ ASSOCIATION 15TH NATIONAL CONFERENCE SATURDAY 14 MAY AND SUNDAY 15 MAY 2016 AUSTRALASIAN SOCIETY OF COSMETIC DERMATOLOGISTS INCLUDES: 3RD ANNUAL MEETING SUNDAY 15 MAY TO TUESDAY 17 MAY 2016 www.dermcoll.edu.au PERTH _ AUSTRALIA’S SUNNIEST CAPITAL CITY WELCOMES YOU TO THE AUSTRALASIAN COLLEGE OF DERMATOLOGISTS 49TH ANNUAL SCIENTIFIC MEETING WELCOME FROM THE PRESIDENT Welcome to Perth, Western Australia for the 49th Annual Scientific Meeting of the Australasian College of Dermatologists. Enclosed in this brochure is the program and other important information for the meeting along with the programs for the meetings of the Australian Dermatology Nurses’ Association and the Australasian Society of Cosmetic Dermatologists. The local organising committee was this year headed by Dr Daniel Hewitt, FACD, and supported by the College’s Scientific Meetings Steering Committee. The Western Australia Faculty welcomes Fellows, trainees, students and other medical practitioners to the meeting. 2 I am excited to welcome our overseas speakers: Professor John McGrath, Professor of Molecular Dermatology and Head of the Genetic Skin Disease Unit at St John’s Institute of Dermatology, King’s College London, United Kingdom. Professor Peter Mortimer, Professor of Dermatological Medicine at St George’s, University of London, United Kingdom. Professor Dirk Elston, Professor and Chairman of the Department of Dermatology and Dermatologic Surgery at the Medical University of South Carolina, Charleston, United States of America. Professor Clark Otley, Chair of the Department of Dermatology and Professor of Dermatology at Mayo Clinic in Rochester, Minnesota, United States of America.
    [Show full text]
  • Acne Related to Dietary Supplements
    Volume 26 Number 8| Aug 2020| Dermatology Online Journal || Commentary 26(8):2 Acne related to dietary supplements Dina H Zamil1 BS, Ariadna Perez-Sanchez2 MD, Rajani Katta3 MD Affiliations: 1Baylor College of Medicine, Houston, Texas, USA, 2University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA, 3McGovern Medical School at University of Texas Health Houston, Houston, Texas, USA Corresponding Author: Rajani Katta MD, 6800 West Loop South, Suite 180, Bellaire, TX 77401, Tel: 281-501-3150, Email: [email protected] Drugs that may induce acne include corticosteroids, Abstract anabolic-androgenic steroids, hormonal drugs, Multiple prescription medications may cause or lithium, antituberculosis medications, and drugs that aggravate acne. A number of dietary supplements contain halogens, specifically iodides and bromides have also been linked to acne, including those [1-7]. There are also reports of acne potentially containing vitamins B6/B12, iodine, and whey, as well induced by cancer therapies, immunosuppressants, as “muscle building supplements” that may be and autoimmune disease medications [7]. contaminated with anabolic-androgenic steroids (AAS). Acne linked to dietary supplements generally Multiple dietary supplements have also been linked resolves following supplement discontinuation. to acne. A number of case reports and series have Lesions associated with high-dose vitamin B6 and described the onset of acne with certain dietary B12 supplements have been described as supplements, with resolution following monomorphic and although pathogenesis is discontinuation of supplement use. These include unknown, a number of hypotheses have been vitamins and dietary ingredients that may seem proposed. Iodine-related acne may be related to the innocuous from the standpoint of the consumer or use of kelp supplements and has been reported as monomorphic, inflammatory pustules on the face physician.
    [Show full text]
  • WO 2012/125941 Al 20 September 2012 (20.09.2012) P O P C T
    (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2012/125941 Al 20 September 2012 (20.09.2012) P O P C T (51) International Patent Classification: (US). JU, William, D. [US/US]; 435 Bernardsville Road, A 59/22 (2006.01) Mendham, NJ 07945 (US). KELLOGG, Scott, C. [US/US]; PO Box 1773, Mattapoisett, MA 02739 (US). (21) International Application Number: PROUTY, Stephen, M. [US/US]; 236 Windsor Way, PCT/US20 12/029475 Doylestown, PA 18901 (US). SCHWEIGER, Eric (22) International Filing Date: [US/US]; 166 East 34th Street, #10B, New York, NY 16 March 2012 (16.03.2012) 10016 (US). LEDERMAN, Seth [US/US]; 200 E. 72nd Street - 35k, New York, NY 10021 (US). OSBAKKEN, English (25) Filing Language: Mary [US/US]; 29 W. Walnut Lane, Suite 300, Phil (26) Publication Language: English adelphia, PA 19144 (US). SCHINAZI, Alan, D. [US/US]; 129 Butler Avenue, Providence, RI 02906 (US). (30) Priority Data: 61/453,895 17 March 201 1 (17.03.201 1) US (74) Agents: CORUZZI, Laura, A. et al; Jones Day, 222 East 61/453,902 17 March 201 1 (17.03.201 1) US 41st Street, New York, NY 10017-6702 (US). 61/453,848 17 March 201 1 (17.03.201 1) US (81) Designated States (unless otherwise indicated, for every 61/453,746 17 March 201 1 (17.03.201 1) US kind of national protection available): AE, AG, AL, AM, 61/5 13,906 1 August 201 1 (01.08.201 1) US AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, 61/525,589 19 August 201 1 (19.08.201 1) US CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, 61/534,156 13 September 201 1 (13.09.201 1) US DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, 61/590,937 26 January 2012 (26.01.2012) US HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, (71) Applicant (for all designated States except US): FOL- KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, LICA, INC.
    [Show full text]
  • 4 Haartalgdruesen SS 09.Pdf
    Klinik für Dermatologie und Allergologie Philipps-Universität Marburg Seminarreihe Dermatologie Erkrankungen der Anhangsgebilde: - Haare insbes. Alopezien - Talgdrüsen insbes. Acne, Rosacea, Rhinophym SS – 2009 Haarzyklus Anagen = Wachstumsphase 3 - 6 Jahre 1/3 mm /d Katagen = Übergangsphase wenige Tage Telogen = Ruhephase 2 - 4 Monate 100 Kolbenhaare /d Haarerkrankungen Begriffsdefinitionen Hypotrichose, Atrichie Î angeborene Verringerung der Haardichte / vollständigesFehlen der Haare Haarerkrankungen Begriffsdefinitionen Hypotrichose, Atrichie Î angeborene Verringerung der Haardichte / vollständigesFehlen der Haare Effluvium Î Haarausfall (d.h. der Vorgang) Anageneffluvium Î während der Wachstumsphase Telogeneffluvium Î während der Ruhephase (Kolbenhaare) Haarerkrankungen Begriffsdefinitionen Hypotrichose, Atrichie Î angeborene Verringerung der Haardichte / vollständigesFehlen der Haare Effluvium Î Haarausfall (d.h. der Vorgang) Anageneffluvium Î während der Wachstumsphase Telogeneffluvium Î während der Ruhephase (Kolbenhaare) Alopezie Î erworbener Verlust der Behaarung (d.h. der Zustand) Alopezie ● diffuse Alopezie: - gleichmäßiger Befall - Musterbildung ("patterned") ● umschriebene Alopezien - herdförmig Alopezie ● vernarbend: irreversibel ● nichtvernarbend: oft reversibel Nichtvernarbende Alopezie, Beispiele ● Androgenetische Alopezie ● Alopecia areata ● Chemisch / medikamentös - Schwermetalle: Thallium, Arsen, Blei etc. - Thyreostatika: Thiouracil, Carbamizol - Antikoagulanzien: Cumarin, Heparin - Retinoide - Zytostatika - u.a.:
    [Show full text]
  • Lecture 3 Dermatology
    Lecture 3 Dermatology Disease Diagnosis Infectious ttt Prevention & transmission herpes location simplex -1 presentation PPT factors Please complete for other disorders in dermatology course Differential Diagnosis Unlike chickenpox, measles shows fever, often greater than 40 °C (104.0 °F), cough, runny nose, and red eyes. A red, flat rash on the body three to five days after the start of symptoms. Measles rash is classically described as a generalized red maculopapular rash 2 Herpes zoster (shingles) • - Chicken pox and herpes zoster are caused by the same virus. • - Following an attack of chicken pox, the virus remain dormant in dorsal root ganglia for many years before some reactivation and causing an attack of shingles. • In Arabic its name means "belt of fire” • Reactivation by stress or by the loss of natural immunity as we get older (more incidence after 50 year). • One attack of shingle generally protects you from a second attack and gives lifelong immunity. • Diagnosis depend on location and presentation 3 Herpes zoster (shingles) • a painful skin rash with blisters involving a limited area. Typically the rash occurs on either the left or right of the body (chest, and abdomen) or face in a single stripe. Two to four days before the rash occurs there may be pain or tingling In the area. • The pain may be mild or sever “ knife-like” • The eruption consists of unilateral, grouped clear or turbid vesicles on erythematous area. • The vesicles dry and forms crust, then it fall of within 2 weeks. but may leave scars. • nerve pain which may last for months or years, a condition called postherpetic neuralgia 4 herpes Zoster Treatment (not OTC) 1- Topical antiviral as acyclovir 2-topical soothing like calamine .
    [Show full text]