Intestinal Obstruction in the Newborn with Special Reference to Transient Functional Ileus Associated with Respiratory Distress Syndrome

Total Page:16

File Type:pdf, Size:1020Kb

Intestinal Obstruction in the Newborn with Special Reference to Transient Functional Ileus Associated with Respiratory Distress Syndrome Arch Dis Child: first published as 10.1136/adc.38.201.459 on 1 October 1963. Downloaded from Arch. Dis. Childh., 1963, 38, 459. INTESTINAL OBSTRUCTION IN THE NEWBORN WITH SPECIAL REFERENCE TO TRANSIENT FUNCTIONAL ILEUS ASSOCIATED WITH RESPIRATORY DISTRESS SYNDROME BY PETER M. DUNN* From the Maternity Hospital, Birmingham (RECEIVED FOR PUBLICATION FEBRUARY 22, 1963) Surgical advances over the last half century have Case 10. Duodenal atresia; severe hydramnios and steadily reduced the mortality from intestinal premature labour; white stools, thick dark green-brown obstruction in the newborn. However, transient vomit and epigastric distension on second day. Radio- intestinal obstruction of functional rather than graph showed typical 'double-bubble' appearance. anatomical origin is not uncommon in the first Surgical correction on third day. Survived. few days of life. As surgery may be strongly Case 11. Ileal atresia; severe hydramnios; pale green contraindicated in this group, the differential stool, copious thick green-brown vomit and upper diagnosis is extremely important. It is hoped that abdominal distension on second day. Radiograph the following study of this problem made in a showed gross distension of intestine as far as the ileum and no gas below this level (Fig. 1). Surgical correction maternity hospital may indicate some of the clinical copyright. signs of value in the differential diagnosis. on second day. Survived. Case 12. Ileal stenosis due to very recent ulceration Clinical Material near the ileo-colic valve secondary to vascular insuffi- ciency; no hydramnios; premature caesarian delivery During 1960 and 1961, 4,754 babies were born at the because of toxaemia of pregnancy; abdominal distension Birmingham Maternity Hospital. Intestinal obstruction and bile-stained vomiting from the third day; meconium was diagnosed either at birth or during the first few passed daily; bowel sounds intermittent; radiograph days of life in 24 infants. In the former there was no (Fig. 2) showed 'general distension of the gut with air diagnostic difficulty; in the latter, the diagnosis was based down to the rectum; a few small fluid levels present; http://adc.bmj.com/ on the presence of at least two and usually all three of probably an ileus rather than an obstruction'. Surgical the following signs-abdominal distension, delayed correction on sixth day. Survived. passage of meconium and bile-stained vomiting. In The remaining 12 infants (Cases 13-24) presented with 12 infants the intestinal obstruction was due to an signs of intestinal obstruction during the first three days anatomical abnormality. In nine (Cases 1-9) this was of life due to either a functional ileus or to a meconium apparent at birth; in three (Cases 10-12) it became plug. Their clinical features are summarized in Table 1 apparent during the first few days of life. Short case and their case histories reported below. summaries are given below. Case 13. A girl, weighing 2 lb. 10 oz. (1,290 g.), was on September 25, 2021 by guest. Protected Case 1. Duodenal atresia; stillborn; maternal delivered by caesarian section at 33 weeks' gestation hydramnios present. because of maternal toxaemia of pregnancy. Condition Case 2. Duodenal stenosis and multiple abnor- at birth was poor and for three days she was critically ill malities; died on first day; no maternal hydramnios. with respiratory distress and cyanotic attacks. Normal Case 3. Ileal atresia; stillborn following a destructive meconium was passed in small amounts from the first operation because of dystocia due to gross foetal day. Generalized abdominal distension and small bile- abdominal distension. No maternal hydramnios. stained vomits were noted on the second day and con- tinued for a further two days. Moderate jaundice also Cases 4-9. Imperforate anus, six cases. One still- developed. From the fifth day steady progress was made born; two with other malformations died; three survived. and she returned home after seven weeks weighing No maternal hydramnios. 4 lb. 11 oz. (2,124 g.). Case 14. This boy, weighing 2 lb. 14 oz. (1,303 g.), *Present address: Bristol Maternitv Hospital, Bristol, was born by normal delivery at 33 weeks. The mother, 459 Arch Dis Child: first published as 10.1136/adc.38.201.459 on 1 October 1963. Downloaded from TABLE SUMMARY OF THE CLINICAL FINDINGS, TREATMENT, Signs of Intestinal Case No. Birth Weight Obstetric and Type of Gestation Abdeminal First Bowel and Sex (lb. oz.) Maternal Factors Delivery (wks) Distenision Action (day) (day) 13 F 2.10 Uterine fibroids; severe pre-eclamptic Caesarian 33 Generalized: 1 d toxaemia section 2%d-4th 14 M 2.14 Severe pre-eclamptic toxaemia; accidental Normal 33 Generalized: 2 antepartum haemorrhage; heavy sedation 3rd-6th 15 M 5.14 Previous caesarian sections for dispropor- Caesarian ?35 GOeneralized: 2 tion section Ist-Sth 16 F 5.2 Placenta praevia; antepartum haemorrhage Caesarian 35 Generalized: 3 section ist-4th 17 M 7.11 Accidental haemorrhage; heavy sedation Normal 36 Generalized: 2 (morphia) and surgical induction 3rd-4th 18 M 5. 15 Hydramnios; bicornuate uterus; premature Breech 32 Generalized: 2 labour 2nd-6th 19 M 7. 10 Diabetes mellitus; moderate hydramnios; Forceps 33 Generalized: 3 premature labour 3rd-4th 20 M 8.0 Diabetes mellitus; moderate hydramnios Caesarian 35 Generalized: 3 section 3rd-4th 21 F 6.2 Diabetes mellitus Caesarian 36 Generalized: 3 section 3rd 22 M 6.5 Twin pregnancy; rhesus immunization Forceps 38 Generalized: 2 Ist-6th 23 F 5. Bicornuate uterus; extended breech presen- Breech 41 Generalized: 2 tation; placental infarction 2nd 24 F 7.12 Placenta praevia; repeated small ante- Caesarian 37 Generalized: 2 partum haemorrhages section 2nd copyright. B = bile-stained. .. http://adc.bmj.com/ on September 25, 2021 by guest. Protected FIG. 1.-Case 11: Ileal atresia on the second day. (a) Supine A-P view; (b) inverted lateral view. Arch Dis Child: first published as 10.1136/adc.38.201.459 on 1 October 1963. Downloaded from RESULTS AND FINAL DIAGNOSIS IN CASES 13-24 Obstruction Character of Vomiting Concomitant Clinical Treatment Result Final Diagnosis First Stool (day) Findings Meconium - (B) Poor condition at birth; severe respiratory distress; Medical Alive Functional ileus 2nd, 3rd, 5th cyanotic attacks; moderate jaundice Meconium - (B) Poor condition at birth; severe respiratory distress; Medical Alive Functional ileus 3rd cyanotic attacks Meconium - (B) Severe respiratory distress; moderate jaundice Medical Alive Functional ileus 2nd-3rd Meconium - (B) Poor condition at birth; severe respiratory distress Medical Alive Functional ileus 2nd Meconium Poor condition at birth; respiratory distress; cyanotic Medical Alive Functional ileus attacks Meconium (B) Poor condition at birth; severe respiratory distress; Medical Alive Functional ileus 2nd-4th severe jaundice Meconium Cushinoid appearance; severe respiratory distress; Medical Alive Functional ileus; plug severe jaundice meconium plug Meconium Cushinoid appearance; respiratory distress Medical Alive Functional ileus; plug 3rd meconium plug Meconium + (B) Respiratory distress Medical Alive Functional ileus; plug 3rd meconiuni plug Meconium (B) First twin; severe Rh haemolytic disease (cord Hb Medical Alive Functional ileus 2nd-6th 35%); exchange transfusion; inspissated bile syndromiie; haemorrhagic disease Meconium Poor condition at birth; cerebral irritability Medical Alive Functional ileus 2nd Meconium -- (B) Poor condition at birth; shock due to foetal Operation Alive Functional ileus: 2nd exsanguination (cord Hb 55%); transfusion at (2nd day) ? meconium plug birth copyright. http://adc.bmj.com/ on September 25, 2021 by guest. Protected FIG. 2.-Case 12. Ileal stenosis near the ileo-colic valve of recent origin on the 3rd day. (a) Supine A-P view; (b) inverted lateral view. Arch Dis Child: first published as 10.1136/adc.38.201.459 on 1 October 1963. Downloaded from 462 ARCHIVES OF DISEASE IN CHILDHOOD aged 36, who had had two abortions previously, had cyanotic attacks attributed to respiratory distress been admitted following an accidental haemorrhage syndrome. Abdominal distension was noted on the complicating severe toxaemia. She was heavily sedated third day and a radiograph on the fourth day showed and when she went into labour shortly afterwards, the moderate gaseous distension of the intestine down to the foetal heart could not be heard. However, the baby was rectum. A trace of meconium was passed on the second born alive, though in very poor condition and rapidly and third days but was not passed in any quantity developed respiratory distress syndrome. For the first until the fourth day. Thereafter the distension subsided two days he was very ill-limp, lethargic, oedematous and progress was normal. and having cyanotic attacks-but thereafter showed improvement, and feeding was commenced. On the Case 18. A boy weighing 5 lb. 15 oz. (2,692 g.) was third day, abdominal distension was noted and he born by breech extraction at 32 weeks' gestation. The vomited bright green material. Only two small meco- mother had been admitted in labour following premature nium stools had been passed since birth, the first on the rupture of the membranes. Because considerable second day. The abdomen was silent. He was treated hydramnios had been noted a stomach tube was passed conservatively over the next four days. There was no soon after birth to exclude oesophageal atresia. The further vomiting and one meconium stool was passed baby was difficult to resuscitate and soon exhibited each day. At the end of the first week, visible bowel signs of respiratory distress syndrome with which pattern was seen, more stools were passed and the dis- condition he remained critically ill for three days. He tension subsided. When 8 weeks old, he was discharged also became severely jaundiced. Feeding was com- weighing 5 lb. (2,267 g.). menced on the second day and at that time abdominal Case 15. This boy was delivered by elective caesarian distension was first noted. This continued until the section at '39' weeks' gestation because of two previous seventh day.
Recommended publications
  • Megaesophagus in Congenital Diaphragmatic Hernia
    Megaesophagus in congenital diaphragmatic hernia M. Prakash, Z. Ninan1, V. Avirat1, N. Madhavan1, J. S. Mohammed1 Neonatal Intensive Care Unit, and 1Department of Paediatric Surgery, Royal Hospital, Muscat, Oman For correspondence: Dr. P. Manikoth, Neonatal Intensive Care Unit, Royal Hospital, Muscat, Oman. E-mail: [email protected] ABSTRACT A newborn with megaesophagus associated with a left sided congenital diaphragmatic hernia is reported. This is an under recognized condition associated with herniation of the stomach into the chest and results in chronic morbidity with impairment of growth due to severe gastro esophageal reflux and feed intolerance. The infant was treated successfully by repair of the diaphragmatic hernia and subsequently Case Report Case Report Case Report Case Report Case Report by fundoplication. The megaesophagus associated with diaphragmatic hernia may not require surgical correction in the absence of severe symptoms. Key words: Congenital diaphragmatic hernia, megaesophagus How to cite this article: Prakash M, Ninan Z, Avirat V, Madhavan N, Mohammed JS. Megaesophagus in congenital diaphragmatic hernia. Indian J Surg 2005;67:327-9. Congenital diaphragmatic hernia (CDH) com- neonate immediately intubated and ventilated. His monly occurs through the posterolateral de- vital signs improved dramatically with positive pres- fect of Bochdalek and left sided hernias are sure ventilation and he received antibiotics, sedation, more common than right. The incidence and muscle paralysis and inotropes to stabilize his gener- variety of associated malformations are high- al condition. A plain radiograph of the chest and ab- ly variable and may be related to the side of domen revealed a left sided diaphragmatic hernia herniation. The association of CDH with meg- with the stomach and intestines located in the left aesophagus has been described earlier and hemithorax (Figure 1).
    [Show full text]
  • Pediatric Gastroesophageal Reflux Clinical Practice
    SOCIETY PAPER Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition ÃRachel Rosen, yYvan Vandenplas, zMaartje Singendonk, §Michael Cabana, jjCarlo DiLorenzo, ôFrederic Gottrand, #Sandeep Gupta, ÃÃMiranda Langendam, yyAnnamaria Staiano, zzNikhil Thapar, §§Neelesh Tipnis, and zMerit Tabbers ABSTRACT This document serves as an update of the North American Society for Pediatric INTRODUCTION Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European n 2009, the joint committee of the North American Society for Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) Pediatric Gastroenterology, Hepatology, and Nutrition (NASP- 2009 clinical guidelines for the diagnosis and management of gastroesophageal GHAN)I and the European Society for Pediatric Gastroenterology, refluxdisease(GERD)ininfantsandchildrenandisintendedtobeappliedin Hepatology, and Nutrition (ESPGHAN) published a medical posi- daily practice and as a basis for clinical trials. Eight clinical questions addressing tion paper on gastroesophageal reflux (GER) and GER disease diagnostic, therapeutic and prognostic topics were formulated. A systematic (GERD) in infants and children (search until 2008), using the 2001 literature search was performed from October 1, 2008 (if the question was NASPGHAN guidelines as an outline (1). Recommendations were addressed
    [Show full text]
  • Abdominal Wall Defects—Current Treatments
    children Review Abdominal Wall Defects—Current Treatments Isabella N. Bielicki 1, Stig Somme 2, Giovanni Frongia 3, Stefan G. Holland-Cunz 1 and Raphael N. Vuille-dit-Bille 1,* 1 Department of Pediatric Surgery, University Children’s Hospital of Basel (UKBB), 4056 Basel, Switzerland; [email protected] (I.N.B.); [email protected] (S.G.H.-C.) 2 Department of Pediatric Surgery, University Children’s Hospital of Colorado, Aurora, CO 80045, USA; [email protected] 3 Section of Pediatric Surgery, Department of General, Visceral and Transplantation Surgery, 69120 Heidelberg, Germany; [email protected] * Correspondence: [email protected]; Tel.: +41-61-704-27-98 Abstract: Gastroschisis and omphalocele reflect the two most common abdominal wall defects in newborns. First postnatal care consists of defect coverage, avoidance of fluid and heat loss, fluid administration and gastric decompression. Definitive treatment is achieved by defect reduction and abdominal wall closure. Different techniques and timings are used depending on type and size of defect, the abdominal domain and comorbidities of the child. The present review aims to provide an overview of current treatments. Keywords: abdominal wall defect; gastroschisis; omphalocele; treatment 1. Gastroschisis Citation: Bielicki, I.N.; Somme, S.; 1.1. Introduction Frongia, G.; Holland-Cunz, S.G.; Gastroschisis is one of the most common congenital abdominal wall defects in new- Vuille-dit-Bille, R.N. Abdominal Wall borns. Children born with gastroschisis have a full-thickness paraumbilical abdominal Defects—Current Treatments. wall defect, which is associated with evisceration of bowel and sometimes other organs Children 2021, 8, 170.
    [Show full text]
  • Guideline for the Evaluation of Cholestatic Jaundice
    CLINICAL GUIDELINES Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition ÃRima Fawaz, yUlrich Baumann, zUdeme Ekong, §Bjo¨rn Fischler, jjNedim Hadzic, ôCara L. Mack, #Vale´rie A. McLin, ÃÃJean P. Molleston, yyEzequiel Neimark, zzVicky L. Ng, and §§Saul J. Karpen ABSTRACT Cholestatic jaundice in infancy affects approximately 1 in every 2500 term PREAMBLE infants and is infrequently recognized by primary providers in the setting of holestatic jaundice in infancy is an uncommon but poten- physiologic jaundice. Cholestatic jaundice is always pathologic and indicates tially serious problem that indicates hepatobiliary dysfunc- hepatobiliary dysfunction. Early detection by the primary care physician and tion.C Early detection of cholestatic jaundice by the primary care timely referrals to the pediatric gastroenterologist/hepatologist are important physician and timely, accurate diagnosis by the pediatric gastro- contributors to optimal treatment and prognosis. The most common causes of enterologist are important for successful treatment and an optimal cholestatic jaundice in the first months of life are biliary atresia (25%–40%) prognosis. The Cholestasis Guideline Committee consisted of 11 followed by an expanding list of monogenic disorders (25%), along with many members of 2 professional societies: the North American Society unknown or multifactorial (eg, parenteral nutrition-related) causes, each of for Gastroenterology, Hepatology and Nutrition, and the European which may have time-sensitive and distinct treatment plans. Thus, these Society for Gastroenterology, Hepatology and Nutrition. This guidelines can have an essential role for the evaluation of neonatal cholestasis committee has responded to a need in pediatrics and developed to optimize care.
    [Show full text]
  • Intestinal Malrotation: a Diagnosis to Consider in Acute Abdomen In
    Submitted on: 05/20/2018 Approved on: 08/07/2018 CASE REPORT Intestinal malrotation: a diagnosis to consider in acute abdomen in newborns Antônio Augusto de Andrade Cunha Filho1, Paula Aragão Coimbra2, Adriana Cartafina Perez-Bóscollo3, Robson Azevedo Dutra4, Katariny Parreira de Oliveira Alves5 Keywords: Abstract Intestinal obstruction, Intestinal malrotation is an anomaly of the midgut, resulting from an embryonic defect during the phases of herniation, Acute abdomen, rotation, and fixation. The objective is to report a case of complex diagnostics and approach. The diagnosis was made Gastrointestinal tract. surgically in a patient presenting with hemodynamic instability, abdominal distension, signs of intestinal obstruction, and pneumoperitoneum on abdominal X-ray, with suspected grade III necrotizing enterocolitis. During surgery, a volvulus resulting from poor intestinal rotation was found at a distance of 12 cm from the ileocecal valve. Hemodynamic instability and abdominal distension recurred, and another exploratory laparotomy was required to correct new intestinal perforations. Therefore, early diagnosis with surgical correction before a volvulus appears is essential. Abdominal Doppler ultrasonography has been promising for early diagnosis. 1 Academic in Medicine - Federal University of the Triângulo Mineiro - Uberaba - Minas Gerais - Brazil 2 Resident in Pediatric Intensive Care - Federal University of the Triângulo Mineiro - Uberaba - Minas Gerais - Brazil 3 Associate Professor - Federal University of the Triângulo Mineiro - Uberaba - Minas Gerais - Brazil. 4 Adjunct Professor - Federal University of the Triângulo Mineiro - Uberaba - Minas Gerais - Brazil 5 Academic in Medicine - Federal University of the Triângulo Mineiro - Uberaba - Minas Gerais - Brazil Correspondence to: Antônio Augusto de Andrade Cunha Filho. Universidade Federal do Triângulo Mineiro, Acadêmico de Medicina - Uberaba - Minas Gerais - Brasil.
    [Show full text]
  • Statistical Analysis Plan
    Cover Page for Statistical Analysis Plan Sponsor name: Novo Nordisk A/S NCT number NCT03061214 Sponsor trial ID: NN9535-4114 Official title of study: SUSTAINTM CHINA - Efficacy and safety of semaglutide once-weekly versus sitagliptin once-daily as add-on to metformin in subjects with type 2 diabetes Document date: 22 August 2019 Semaglutide s.c (Ozempic®) Date: 22 August 2019 Novo Nordisk Trial ID: NN9535-4114 Version: 1.0 CONFIDENTIAL Clinical Trial Report Status: Final Appendix 16.1.9 16.1.9 Documentation of statistical methods List of contents Statistical analysis plan...................................................................................................................... /LQN Statistical documentation................................................................................................................... /LQN Redacted VWDWLVWLFDODQDO\VLVSODQ Includes redaction of personal identifiable information only. Statistical Analysis Plan Date: 28 May 2019 Novo Nordisk Trial ID: NN9535-4114 Version: 1.0 CONFIDENTIAL UTN:U1111-1149-0432 Status: Final EudraCT No.:NA Page: 1 of 30 Statistical Analysis Plan Trial ID: NN9535-4114 Efficacy and safety of semaglutide once-weekly versus sitagliptin once-daily as add-on to metformin in subjects with type 2 diabetes Author Biostatistics Semaglutide s.c. This confidential document is the property of Novo Nordisk. No unpublished information contained herein may be disclosed without prior written approval from Novo Nordisk. Access to this document must be restricted to relevant parties.This
    [Show full text]
  • Appendix 3.1 Birth Defects Descriptions for NBDPN Core, Recommended, and Extended Conditions Updated March 2017
    Appendix 3.1 Birth Defects Descriptions for NBDPN Core, Recommended, and Extended Conditions Updated March 2017 Participating members of the Birth Defects Definitions Group: Lorenzo Botto (UT) John Carey (UT) Cynthia Cassell (CDC) Tiffany Colarusso (CDC) Janet Cragan (CDC) Marcia Feldkamp (UT) Jamie Frias (CDC) Angela Lin (MA) Cara Mai (CDC) Richard Olney (CDC) Carol Stanton (CO) Csaba Siffel (GA) Table of Contents LIST OF BIRTH DEFECTS ................................................................................................................................................. I DETAILED DESCRIPTIONS OF BIRTH DEFECTS ...................................................................................................... 1 FORMAT FOR BIRTH DEFECT DESCRIPTIONS ................................................................................................................................. 1 CENTRAL NERVOUS SYSTEM ....................................................................................................................................... 2 ANENCEPHALY ........................................................................................................................................................................ 2 ENCEPHALOCELE ..................................................................................................................................................................... 3 HOLOPROSENCEPHALY.............................................................................................................................................................
    [Show full text]
  • Duplication Cyst with Intestinal Volvulus Causing Intestinal Atresia/Stenosis in Neonates
    Journal of Neonatal Surgery 2018; 7:43 DOI: 10.21699/jns.v7i4.820. CASE SERIES Duplication Cyst with Intestinal Volvulus Causing Intestinal Atresia/Stenosis in Neonates Muhammad Bilal Mirza*, Imran Hashim, Shabbir Ahmad, Nabila Talat, M Zubair Shaukat, Muhammad Saleem Department of Pediatric Surgery, The Children’s Hospital and The Institute of Child Health, Lahore, Pakistan How to cite: Mirza B, Hashim I, Ahmad S, Talat N, Shaukat MZ, Saleem M. Duplication cyst with intestinal volvulus causing intestinal atresia/ stenosis in neonates. J Neonatal Surg. 2018; 7:43. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT Duplication cysts of small bowel seldom present in newborns and usually represent the development of complications. In utero complications may lead to mesenteric vascular accidents and thus resulting in intestinal atresias. We report three neonates with duplication cyst of small bowel causing localized intestinal volvulus, leading to small bowel intestinal atresia/stenosis. The neonates underwent excision of the duplication cyst and resection anastomosis of the small bowel. Post-operative recovery was uneventful in all three of them. Key words: Atresia; Duplication cyst; Stenosis; Volvulus INTRODUCTION sound of abdomen showed dilated bowel loops. After adequate resuscitation, the patient was operated with Volvulus due to duplication cyst is a rare cause of suspicion of intestinal atresia. At surgery, a 3 cm × neonatal intestinal obstruction [1]. In utero volvulus 5 cm sized non-communicating cyst was encountered due to duplication cyst may also produce intestinal with 3–4 twists causing localized volvulus.
    [Show full text]
  • Congenital Pyloric Atresia: Clinical Features, Diagnosis, Associated Anomalies, Management and Outcome Osama A
    188 Original article Congenital pyloric atresia: clinical features, diagnosis, associated anomalies, management and outcome Osama A. Bawazira,b and Ahmed H. Al-Salemc Background Congenital pyloric atresia (CPA) is very rare period; however, 10 died later giving an overall survival of and usually seen as an isolated anomaly, which has an 40%. Sepsis was the main cause of death. excellent prognosis. CPA can be associated with other Conclusion CPA is a very rare malformation that can be anomalies or familial and these are usually associated with familial and inherited as an autosomal recessive. It can other hereditary conditions with poor prognosis. This either occur as an isolated lesion with an excellent review is based on our experience with 20 infants with CPA. prognosis, or be associated with other anomalies. Patients and methods This is a review of CPA, The overall prognosis of CPA, however, is still poor, and this highlighting its clinical features; associated anomalies; and is due to the frequent-and often fatal-associated aspects of diagnosis, management and outcome. anomalies. Ann Pediatr Surg 13:188–193 c 2017 Annals of Pediatric Surgery. Results This review is based on our experience with 20 patients with CPA (nine male and 11 female). Their mean Annals of Pediatric Surgery 2017, 13:188–193 birth weight was 2.1 kg (1.1-3.9 kg). Polyhydramnios was Keywords: aplasia cutis congenita, congenital pyloric atresia, seen in 13 (65%) patients. Seven patients were full-term epidermolysis bullosa, hereditary multiple intestinal atresia and the remaining 13 were premature. Two were brothers aDepartment of Surgery, Faculty of Medicine, Umm Al Qura University, Makkah, and four were members of the same family.
    [Show full text]
  • Nova Scotia Atlee Perinatal Database Coding Manual 15 Edition (Version
    Nova Scotia Atlee Perinatal Database Coding Manual 15th Edition (Version 15.0.0) April 2011 TABLE OF CONTENTS LISTINGS OF HOSPITALS 11 ADMISSION INFORMATION 16 DELIVERED ADMISSION 26 Routine Information – Delivered Admission 26 Routine Information – Labour 57 Routine Information – Infant 77 UNDELIVERED ADMISSION 94 Routine information – undelivered 94 POSTPARTUM ADMISSIONS 104 Routine Information – Postpartum Admission 104 NEONATAL ADMISSIONS 112 Routine Information – Neonatal Admissions 112 ADULT RCP CODES 124 INFANT RCP CODES 143 INDEX OF MATERNAL DISEASES AND PROCEDURES 179 INDEX OF NEONATAL DISEASES AND PROCEDURES 195 1 INDEX FOR ADMISSION INFORMATION Admission date .............................................................................................................................. 17 Admission time .............................................................................................................................. 17 Admission process status ............................................................................................................... 25 Admission type .............................................................................................................................. 17 A/S/D number ................................................................................................................................ 18 Birth date ....................................................................................................................................... 18 Care provider attending ................................................................................................................
    [Show full text]
  • The Gastrointestinal Tract Frank A
    91731_ch13 12/8/06 8:55 PM Page 549 13 The Gastrointestinal Tract Frank A. Mitros Emanuel Rubin THE ESOPHAGUS Bezoars Anatomy THE SMALL INTESTINE Congenital Disorders Anatomy Tracheoesophageal Fistula Congenital Disorders Rings and Webs Atresia and Stenosis Esophageal Diverticula Duplications (Enteric Cysts) Motor Disorders Meckel Diverticulum Achalasia Malrotation Scleroderma Meconium Ileus Hiatal Hernia Infections of the Small Intestine Esophagitis Bacterial Diarrhea Reflux Esophagitis Viral Gastroenteritis Barrett Esophagus Intestinal Tuberculosis Eosinophilic Esophagitis Intestinal Fungi Infective Esophagitis Parasites Chemical Esophagitis Vascular Diseases of the Small Intestine Esophagitis of Systemic Illness Acute Intestinal Ischemia Iatrogenic Cancer of Esophagitis Chronic Intestinal Ischemia Esophageal Varices Malabsorption Lacerations and Perforations Luminal-Phase Malabsorption Neoplasms of the Esophagus Intestinal-Phase Malabsorption Benign tumors Laboratory Evaluation Carcinoma Lactase Deficiency Adenocarcinoma Celiac Disease THE STOMACH Whipple Disease Anatomy AbetalipoproteinemiaHypogammaglobulinemia Congenital Disorders Congenital Lymphangiectasia Pyloric Stenosis Tropical Sprue Diaphragmatic Hernia Radiation Enteritis Rare Abnormalities Mechanical Obstruction Gastritis Neoplasms Acute Hemorrhagic Gastritis Benign Tumors Chronic Gastritis Malignant Tumors MénétrierDisease Pneumatosis Cystoides Intestinalis Peptic Ulcer Disease THE LARGE INTESTINE Benign Neoplasms Anatomy Stromal Tumors Congenital Disorders Epithelial Polyps
    [Show full text]
  • Duodenal Stenosis: a Diagnostic Challenge in a Neonate with Poor Weight Gain
    Open Access Case Report DOI: 10.7759/cureus.8559 Duodenal Stenosis: A Diagnostic Challenge in a Neonate With Poor Weight Gain Ma Khin Khin Win 1 , Carole Mensah 1 , Kunal Kaushik 1 , Louisdon Pierre 1 , Adebayo Adeyinka 1 1. Pediatrics, The Brooklyn Hospital Center, Brooklyn, USA Corresponding author: Carole Mensah, [email protected] Abstract Cases of isolated duodenal stenosis in the neonatal period are minimally reported in pediatric literature. Causes of small bowel obstruction such as duodenal atresia or malrotation with midgut volvulus have been well documented and are often diagnosed due to their acute clinical presentation. Duodenal stenosis, however, causes an incomplete intestinal obstruction with a more indolent and varying clinical presentation thus making it a diagnostic challenge. We present a neonate with a unique case of congenital duodenal stenosis. The neonate presented with poor weight gain and frequent "spit-ups" as per the mother at the initial newborn visit. The clinical presentation was masked as the patient was being fed infrequently and with concentrated formula. We postulate that this may be due to the fact that the mother was an adolescent and relatively inexperienced with newborn care. During the hospital course, the patient had recurrent episodes of emesis with notable electrolyte abnormalities including hypochloremia and metabolic alkalosis. Further investigation with an abdominal X-ray showed dilated loops of bowel. Pyloric stenosis was ruled out via abdominal ultrasound. An upper gastrointestinal (GI) series ultimately confirmed a diagnosis of duodenal stenosis and the infant underwent surgical repair with full recovery. Congenital duodenal stenosis may have atypical presentations in neonates requiring pediatricians to have a high index of suspicion for diagnosis and to ensure timely therapy.
    [Show full text]