List of Genes Associated with Nasopharyngeal Carcinoma Gene Symbol Gene Name Reference

Home , APEX1, ELF2, Homeobox A10, NFE2, Sp1 transcription factor

List of genes associated with nasopharyngeal carcinoma Gene symbol Gene name Reference

LOC344967 Acyl-CoA thioesterase 7 pseudogene 16423998

ITGA9 Integrin subunit alpha 9 19478819, 26372814

EBNA1 Nuclear antigen EBNA-1 22815911, 24190575, 24460960, 24753359, 28810605

LMP1 Latent membrane protein LMP-1 22815911, 14678988, 23868181, 27049918, 23939952

LMP2 Membrane protein LMP-2A 17980397, 24630965, 26292668, 22815911

BARF1 BARF1 protein BARF1 22815911, 15778977, 29562599, 23996634, 22406129

FHIT Fragile histidine triad 22815911, 23534718

EGFR Epidermal growth factor receptor 23416081, 26339373, 28129778, 18367518, 27203742

COX2 Cytochrome c oxidase subunit II 23416081, 25553117, 26261650, 28435473, 28732079

CCNE1 Cyclin E1 23416081 hTERT Telomerase reverse transcriptase 23416081, 24648937, 21233856, 24615621, 25153197

MMP2 Matrix metallopeptidase 2 23416081, 28129778, 17607721, 25066400, 26546460

MMP9 Matrix metallopeptidase 9 23416081, 23409137, 22957092, 24243817, 28380444

NF-κB Nuclear factor kappa B subunit 1 23416081, 28380444, 23868181, 28969015, 26172457 VEGF Vascular endothelial growth factor A 23416081, 28243126, 26275421, 21233856, 26717040

WNT3 Wnt family member 3 23416081

URG4/URGCP Upregulator of cell proliferation 29775749, 28315691

TNFAIP2 TNF alpha induced protein 2 21057457, 23975427

FAS Fas cell surface death receptor 16473667, 26275421

TRIM26 Tripartite motif containing 26 29956500

PTEN Phosphatase and tensin homolog 24604064, 25365510, 24632578, 20053927, 27840403

CDK5 Cyclin dependent kinase 5 26339373

P53 Tumor protein p53 26339373, 26893866, 24262659, 24632578, 28081741

CDH13 Cadherin 13 16807071

HOXA2 Homeobox A2 24243817

HER2 erb-b2 receptor tyrosine kinase 2 11850071

STAT3 Signal transducer and activator of transcription 3 25365510, 16516862, 18367518, 27538493, 26779625

IL-6 Interleukin 6 25365510, 28732079, 25970784

AKT AKT serine/threonine kinase 1 25365510, 14678988, 29936709, 27270423, 24632578 cdc42 Cell division cycle 42 14678988, 24877689 c-Jun Jun proto-oncogene, AP-1 transcription factor subunit 14678988, 27270423, 27533465, 25571870, 22727408

Bcl-3 BCL3, transcription coactivator 14678988, 18367518

IFN-γ Interferon gamma 23272637, 28810605 ING4 Inhibitor of growth family member 4 25571952

ANGPT1 Angiopoietin 1 26722421

LMP2A Membrane protein LMP-2A 17980397, 24630965, 26292668

EBNA2 Nuclear antigen EBNA-2 17980397

Notch1 Notch 1 17980397, 26621837, 24281414, 28581676

Notch3 Notch 3 22009689, 27035429

RUNX3 Runt related transcription factor 3 17201146

P16 Cyclin dependent kinase inhibitor 2A 17201146, 26294655, 24460960, 21445878, 27326252

RASSF1A Ras association domain family member 1 17201146, 25196065, 26443805, 11358799, 20042089 hMLH1 MutL homolog 1 17201146

Annexin A1 Annexin A1 28355254, 25322804

S100A9 S100 calcium binding protein A9 28355254

Vimentin Vimentin 28355254, 25823923, 23688988

FBLN2 Fibulin 2 21743496, 22360856

ECM Multimerin 1 21743496

BLU Zinc finger MYND-type containing 10 25347745, 22727408, 28029652, 22360856

β-catenin Catenin beta 1 29552214, 29764469, 29536130, 28569772, 26497204 Wnt Protein Wnt-2 29552214, 23649311, 29764469, 29536130, 27769064

XRCC1 X-ray repair cross complementing 1 24175791, 24940494, 25025378, 27356695, 25481674

OGG1 8-oxoguanine DNA glycosylase 24175791, 29121049

APE1 Apurinic/apyrimidinic endodeoxyribonuclease 1 24175791

HLA-E Major histocompatibility complex, class I, E 26896927

AGO2 Argonaute RISC catalytic component 2 26545861

ARHGAP42 Rho GTPase activating protein 42 29936709

PI3K Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 29936709, 27270423, 28644386, 25126743, 26698246

CCND1 Cyclin D1 16166286, 27270423, 28581676, 28969015, 22009689

PIN1 Peptidylprolyl cis/trans isomerase, NIMA-interacting 1 23269625

Cav-1 Caveolin 1 21965789

CELF2 CUGBP Elav-like family member 2 26314850

IL-1b Interleukin 1 beta 18289837, 26391153

IL-10 Interleukin 10 23898109

IL-18 Interleukin 18 24066061, 18555694

LAPTM4B Lysosomal protein transmembrane 4 beta 23345117

DC-SIGN CD209 molecule 28694559, 21067616

IL-2 Interleukin 2 20438365

GSTM1 Glutathione S-transferase mu 1 26893866, 18628429

APEX1 Apurinic/apyrimidinic endodeoxyribonuclease 1 28464393

XRCC3 X-ray repair cross complementing 3 24940494, 24453273

BEX3 brain expressed X-linked 3 28083995

OCT4 POU class 5 homeobox 1 28083995

Ets-1 ETS proto-oncogene 1, transcription factor 2752597, 28672814

Pim-3 Pim-3 proto-oncogene, serine/threonine kinase 2752597

SSRP1 Structure specific recognition protein 1 2752597

BRCC3 BRCA1/BRCA2-containing complex subunit 3 26024915

BRD7 Bromodomain containing 7 15137061, 19111069

E2F3 E2F transcription factor 3 15137061, 25630654, 27461945

KRAS KRAS proto-oncogene, GTPase 15137061, 28581676, 25701793, 21878506, 28857155

MEK Mitogen-activated protein kinase kinase 7 15137061

REK TYRO3 protein tyrosine kinase 15137061

Rb RB transcriptional corepressor 1 15137061, 20053927

E2F1 E2F transcription factor 1 15137061, 20053927

ATM ATM serine/threonine kinase 24262659, 29230817, 27883284

Chk2 Checkpoint kinase 2 24262659

Chk1 Checkpoint kinase 1 24262659, 26025928, 24117075

Caspase 12 Caspase 12 28380444

CD44 CD44 molecule 22887934, 24073846, 27809309

CIP4 Thyroid hormone receptor interactor 10 22591637, 23883608

CDH4 Cadherin 4 28129778, 2821940

CFTR Cystic fibrosis transmembrane conductance regulator 21665361

MTAP Methylthioadenosine phosphorylase 27769067

CACNA2D3 Calcium voltage-gated channel auxiliary subunit alpha2delta 3 26656376

CMYC MYC proto-oncogene, bHLH transcription factor 23649311

MMP7 Matrix metallopeptidase 7 23649311, 28969015, 21233856, 29052525, 10685630

SNAIL Snail family transcriptional repressor 1 23649311, 22957092, 23128850, 28656063

PDK1 Pyruvate dehydrogenase kinase 1 23649311, 26497204

MIPOL1 Mirror-image polydactyly 1 29764469, 26547584, 30001734 p21(CDKN1A) Cyclin dependent kinase inhibitor 1A 19667180 p27 (KIP1) Cyclin dependent kinase inhibitor 1B 19667180, 25265349, 29434867, 23783436, 29052525

BTG1 BTG anti-proliferation factor 1 19667180, 23783436, 25749514, 28315691, 23783436

ET1 Endothelin 1 29536130

PDCD4 Programmed cell death 4 29536130, 28199751, 28199751

HGF Hepatocyte growth factor (Homo sapiens) 27270423

Met MET proto-oncogene, receptor tyrosine kinase 26345996

KAI1 CD82 molecule 26345996, 26795575, 25611392, 25965822

NPCEDRG Nicolin 1 25789023, 28583320

HHATL Hedgehog acyltransferase like 20821255

BI-1 Transmembrane BAX inhibitor motif containing 6 16234092

MDM2 MDM2 proto-oncogene 24648937, 21545297

CLPTM1L CLPTM1 like 24632578, 23677067, 27883284, 20398418, 20395212

IDH2 Isocitrate dehydrogenase [NADP(+)] 2, mitochondrial 26621837, 24615621

MAP3K1 Mitogen-activated protein kinase kinase kinase 1 28581676

CDKN2A Cyclin dependent kinase inhibitor 2A 28581676

SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 28581676, 26275421, 12800147, 23790641, 28445979

RAD51L1 RAD51 paralog B 28581676

BRCA1 BRCA1, DNA repair associated 21368091

TP53BP1 Tumor protein p53 binding protein 1 21368091, 28857155

EBNA3A Nuclear antigen EBNA-3A 21368091

BZLF1 Protein Zta 26969667

BRLF1 Protein Rta 26969667, 8212572, 23409137, 27185626

BMRF1 DNA polymerase processivity subunit 26969667, 29108278, 22641235, 27185626

BRCA2 BRCA2, DNA repair associated 26969667 p50 Hypothetical protein 28857155

MYB MYB proto-oncogene, transcription factor 23868181, 18367518

BCL2 BCL2, apoptosis regulator 23868181, 22260379

Bcl3 BCL3, transcription coactivator 23868181, 22009689, 26795575, 25031780, 28969015

RelB RELB proto-oncogene, NF-kB subunit 23868181

TRAF3 TNF receptor associated factor 3 23868181, 28452850

TRAF2 TNF receptor associated factor 2 23868181

NFKBIA NFKB inhibitor alpha 23868181

A20 TNF alpha induced protein 3 23868181, 27647909

NRP-1 Neuropilin 1 23868181, 28969015

OPN Secreted phosphoprotein 1 26755049

CDK4 Cyclin dependent kinase 4 24913806

CYP2E1 Cytochrome P450 family 2 subfamily E member 1 24771220, 25630654, 26383521, 26559153, 24168228

CYB5R2 Cytochrome b5 reductase 2 9274915, 11389775, 8547826, 25481674

FOS Fos proto-oncogene, AP-1 transcription factor subunit 24338690, 26275421

PIK3R1 Phosphoinositide-3-kinase regulatory subunit 1 26275421

ITGB3 Integrin subunit beta 3 26275421

ITGB5 Integrin subunit beta 5 26275421

IGF1 Insulin like growth factor 1 26275421

TEK TEK receptor tyrosine kinase 26275421

TGFBR1 Transforming growth factor beta receptor 1 26275421

NKG2D NKG2D protein (Macaca mulatta) 26275421

FKHRL1 Forkhead box O3 26418951, 28452850

GSK3β Glycogen synthase kinase 3 beta 25749514 Sox2 SRY-box 2 25749514, 27916418, 28569772, 27769064, 27623076

ULBP4 Retinoic acid early transcript 1E 25749514, 29463902

ASS1 Argininosuccinate synthase 1 28159927

PEDF Serpin family F member 1 23897555

LRP6 LDL receptor related protein 6 28569772

DEPDC1 DEP domain containing 1 28569772

CCNB1 Cyclin B1 28969015

CCNB2 Cyclin B2 28969015

NFBD1 Mediator of DNA damage checkpoint 1 28969015

CCNL1 Cyclin L1 26247734, 27334757, 28081741

PTK2 Protein tyrosine kinase 2 29927011

DLC-1 DLC1 Rho GTPase activating protein 29927011

TSG Twisted gastrulation BMP signaling modulator 1 23908159, 22824824

ECRG4 Chromosome 2 open reading frame 40 23908159

ATOH8 Atonal bHLH transcription factor 8 27119734, 27119734, 25707757

Cx43 Gap junction protein alpha 1 27049918

Sp1 Sp1 transcription factor 17306607

ZEB1 Zinc finger E-box binding homeobox 1 27698878, 22260379, 27185626, 26922862, 25161098

CRKL CRK like proto-oncogene, adaptor protein 26936585, 24190575

ETS2 ETS proto-oncogene 2, transcription factor 26936585

TMEM54 Transmembrane protein 54 22260379

PCBP1 Poly(rC) binding protein 1 22260379

NFE2 Nuclear factor, erythroid 2 22260379

KLF6 Kruppel like factor 6 22260379

Drp1 Dynamin 1 like 22260379

PSCA Prostate stem cell antigen 28435473

SDHB Succinate dehydrogenase complex iron sulfur subunit B 26147638 p63 Tumor protein p63 26547584

Egr-1 Early growth response 1 16516862, 29562599

Cabin1 Calcineurin binding protein 1 22947087, 20635349

JNK Mitogen-activated protein kinase 8 23939952

ERK=MAPK1=ERK2 Mitogen-activated protein kinase 1 23939952, 26546460, 22727408

ERK1 Extracellular signal-regulated kinase 1 23939952, 27538493, 21878506, 28659184, 27756261

TLR3 Toll like receptor 3 27756261, 27567526, 28946771, 26546460

TNFα Tumor necrosis factor 26172457 PSAT1 Phosphoserine aminotransferase 1 26172457, 16970270, 28968968

PHGDH Phosphoglycerate dehydrogenase 23685147, 27326252

BTRC Beta-transducin repeat containing E3 ubiquitin protein ligase 23685147

βTrCP Beta-transducin repeat containing E3 ubiquitin protein ligase 26497204 MDR1 ATP binding cassette subfamily B member 1 26497204

AKT3 AKT serine/threonine kinase 3 25900553, 24376145, 17545060, 23128850

ALDH1 Aldehyde dehydrogenase 1 family member A1 23128850

CD31 Platelet and endothelial cell adhesion molecule 1 23128850

IL-4 Interleukin 4 23128850

HSP70 Heat shock protein family A (Hsp70) member 4 23128850

HSP70-2 Heat shock protein family A (Hsp70) member 2 23128850

DAPK Death associated protein kinase 1 23667540, 12691826

Bmi-1 BMI1 proto-oncogene, polycomb ring finger 16520653, 25196065, 23790641

WNT5A Wnt family member 5A 26294655, 25171860, 21445878, 29701183

E-cad Cadherin 1 25066400, 25823923

CANX Calnexin 25066400, 26530812, 27150436, 26297956, 29327067

CALCR Calcitonin receptor 28216622

VCP Valosin containing protein 28216622

NGX6 Transmembrane protein 8B 28216622, 26506425

CD93 CD93 molecule 29243779, 12474055, 26880583

TESTIN Testin LIM domain protein 27255994

Survivin Baculoviral IAP repeat containing 5 25824796

FN1 Fibronectin 1 21233856, 25867400, 22009689, 24376145, 25824761

ITGB1 Integrin subunit beta 1 28613134, 26773938

ITGAV Integrin subunit alpha V 28613134

CDK2 Cyclin dependent kinase 2 [Homo sapiens 28613134

CCNA1 Cyclin A1 25265349, 23783436, 24460960, 25630654, 28350089

INCA1 Inhibitor of CDK, cyclin A1 interacting protein 1 25265349, 26443805, 22140479, 17689134

EMP2 Epithelial membrane protein 2 25265349 mTOR Mechanistic target of rapamycin kinase 28347228

Beclin-1 Beclin 1 28644386 p62 Sequestosome 1 28644386

Fap-1 Protein tyrosine phosphatase, non-receptor type 13 28644386

Bax BCL2 associated X, apoptosis regulator 28644386

IL-24 Interleukin 24 23783436, 27916418, 26239171

UBE2L6 Ubiquitin conjugating enzyme E2 L6 23783436

ATGL Patatin like phospholipase domain containing 2 26506425

CHFR Checkpoint with forkhead and ring finger domains 26506425

INPP4B Inositol polyphosphate-4-phosphatase type II B 15937956, 22070084, 22824824

TSLC1 Cell adhesion molecule 1 25126743

WIF1 WNT inhibitory factor 1 14639656

DAPK1 Death associated protein kinase 1 25196065, 26443805, 16427602

RARB Retinoic acid receptor beta (Homo sapiens) 25196065, 23790641

ZNF671 Zinc finger protein 671 25196065

BALF3 DNA packaging terminase subunit 2 29052525

ZEB2 Zinc finger E-box binding homeobox 2 25261366

MMP1 Matrix metallopeptidase 1 24190575

MMP3 Matrix metallopeptidase 3 23409137, 28672814, 25481674

UBQLN1 Ubiquilin 1 23409137

ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit 26698246 p65 RELA proto-oncogene, NF-kB subunit 25025378, 24376145

MDK Midkine 26546460, 28732079, 23975427, 28968968, 26781335

STAT1 Signal transducer and activator of transcription 1 30001734

FGF11 Fibroblast growth factor 11 27538493, 21874234, 29492196, 23174573

EIF5A2 Eukaryotic translation initiation factor 5A2 27538493

WWOX WW domain containing oxidoreductase 27549330 mTORC1=RHEB Ras homolog, mTORC1 binding 23534718, 24299313

Glut-1 Solute carrier family 2 member 1 28053105

PMS2 PMS1 homolog 2, mismatch repair system component 28053105

Fbxw7 F-box and WD repeat domain containing 7 21571466

FEZF2 FEZ family zinc finger 2 26886596

EZH2 Enhancer of zeste 2 polycomb repressive complex 2 subunit 23677067

FGF8b Fibroblast growth factor 8 23677067, 22972404, 27040767

FLJ10540 Centrosomal protein 55 21119603 osteopontin Secreted phosphoprotein 1 22591637

TGF-β Transforming growth factor beta 1 22591637 Flot2 Flotillin 2 25909165, 22282866

Int-2 Fibroblast growth factor 3 25909165

Myocardin Myocardin 10685630

PTPRG Protein tyrosine phosphatase, receptor type G 20848417

THY1 Thy-1 cell surface antigen 18829573, 25970784

TRPM7 Transient receptor potential cation channel subfamily M member 7 19921696, 16007174

GALNT7 Polypeptide N-acetylgalactosaminyltransferase 7 26779625

CDK16 Cyclin dependent kinase 16 25809707, 26503214

PCDH10 Protocadherin 10 25809707

DNMT1 DNA methyltransferase 1 16247458

DNMT3B DNA methyltransferase 3 beta 16247458, 26530812

NBS1 Nibrin 16247458, 26975503

BIRC5 Baculoviral IAP repeat containing 5 21656575

CR2 Complement C3d receptor 2 21304814

GALC Galactosylceramidase 23612877

CCND2 Cyclin D2 26178533

FOLR1 Folate receptor 1 20473882, 28350089

GM-CSF Colony stimulating factor 2 26617855

B7-1 CD80 molecule 18999931, 28732079

CTNNB1 Catenin beta 1 18999931

SFRP1 Secreted frizzled related protein 1 27769064

UCHL1 Ubiquitin C-terminal hydrolase L1 26443805

TP73 Tumor protein p73 26443805, 23790641, 20395212

ABCC5 ATP binding cassette subfamily C member 5 26443805

PEG10 Paternally expressed 10 22824824, 28277541

ERBB2 Erb-b2 receptor tyrosine kinase 2 22824824

GSTP1 Glutathione S-transferase pi 1 22824824, 24481647

GLRX3 Glutaredoxin 3 22824824, 21874234

GSTT1 Glutathione S-transferase theta 1 27203742

XPD Xeroderma pigmentosum D 18628429 hOGG1 8-oxoguanine DNA glycosylase 29121049

ITGA2 Integrin subunit alpha 2 29121049

XPA XPA, DNA damage recognition and repair factor 29121049

HMGA2 High mobility group AT-hook 2 26156020

TAZ WW domain containing transcription regulator 1 26183485, 25884389

BCR2 Breakpoint cluster region pseudogene 2 28749195

HOXA10 Homeobox A10 1371012

ZIC2 Zic family member 2 28338202

Jab1 COP9 signalosome subunit 5 28338202

CSN5 COP9 signalosome subunit 5 27157611

HLA-A Major histocompatibility complex, class I, A 27157611

HLA-B Major histocompatibility complex, class I, B 24367763

HCG9 HLA complex group 9 24367763

GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 24367763

SPLUNC1 BPI fold containing family A member 1 24367763

TTC40 Cilia and flagella associated protein 46 22213098, 20053927, 25161098, 25161098

UBR5 Ubiquitin protein ligase E3 component n-recognin 5 25101295

ZNF423 Zinc finger protein 423 23878065

CCL5 C-C motif chemokine ligand 5 23878065

STAT2 Signal transducer and activator of transcription 2 21874234, 29569795, 24080422

SRC SRC proto-oncogene, non-receptor tyrosine kinase 21874234

SMAD3 SMAD family member 3 29393436, 27756261

YWHAZ Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 29393436

HSPA4 Heat shock protein family A (Hsp70) member 4 29393436

IGFBP6 Insulin like growth factor binding protein 6 29393436

EGR-1 Early growth response 1 27623076 caspase-1 Caspase 1 20635349

TSP-1 Thrombospondin 1 20635349

IKBB NFKB inhibitor beta 20635349, 25857718

IL-1RN Interleukin 1 receptor antagonist 26227166

EDNRA Endothelin receptor type A 23562526

MSH3 Muts homolog 3 28199751 parkin Parkin RBR E3 ubiquitin protein ligase 28656302

CLDN11 Claudin 11 28351314

IKKa Conserved helix-loop-helix ubiquitous kinase 29747653

IRS-1 Insulin receptor substrate 1 24753359

PIK3CA Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 25337259

POLG DNA polymerase gamma, catalytic subunit 26581613 eEF-2 Eukaryotic translation elongation factor 2 29763377

NOTCH3 Notch 3 27756261

BCL-XL BCL2 like 1 22009689, 27035429

MLL Lysine methyltransferase 2A 22009689, 15663904

CAD DNA fragmentation factor subunit beta 26019688

ICAD DNA fragmentation factor subunit alpha 26019688

CDK6 Cyclin dependent kinase 6 26019688

MLL3 Lysine methyltransferase 2C 26795575

WNT7A Wnt family member 7A 26014803

PPP2R2C Protein phosphatase 2 regulatory subunit Bgamma 26372814

IL-35 Interleukin 12A 28525724

CCR9 C-C motif chemokine receptor 9 26034389

CCL25 C-C motif chemokine ligand 25 26279399

ISG15 ISG15 ubiquitin-like modifier 26279399

JMJD2A Lysine demethylase 4A 26919245

LDHA Lactate dehydrogenase A 28693517 pRb RB transcriptional corepressor 1 28693517, 27458165

DP2 APC, WNT signaling pathway regulator 25630654

TKTL1 Transketolase like 1 25630654

PLAC8 Galectin 13 27916418

LATS2 Large tumor suppressor kinase 2 27916418

HMGA2 High mobility group AT-hook 2 20932276 eIF4E Eukaryotic translation initiation factor 4E 25884389

NLRP3 NLR family pyrin domain containing 3 24814906

IL-1β Interleukin 1 beta 28732079 IL-6 Interleukin 6 28732079

NUAK1 NUAK family kinase 1 28732079, 28987345

S100A1 S100 calcium binding protein A1 29575772

H19 H19, imprinted maternally expressed transcript 29248577

VEGFA Vascular endothelial growth factor A 27040767, 12569573

Ang2 Angiopoietin 2 26717040

KLF12 Kruppel like factor 12 26717040

ELF2 E74 like ETS transcription factor 2 28328537

LTBP-2 Latent transforming growth factor beta binding protein 2 28728844

LZTS2 Leucine zipper tumor suppressor 2 22743615 p85 Phosphoinositide-3-kinase regulatory subunit 1 29409973

MnSOD Superoxide dismutase 2 29409973

MMP12 Matrix metallopeptidase 12 27083052

MMP14 Matrix metallopeptidase 14 24885469

CCR2 C-C motif chemokine receptor 2 25829357

CXCR6 C-X-C motif chemokine receptor 6 26058873

CXCL16 C-X-C motif chemokine ligand 16 26058873

CCL2 C-C motif chemokine ligand 2 26058873

TSGA10 Testis specific 10 26058873

NID2 Nidogen 2 29520105

FAK Protein tyrosine kinase 2 27793011

PLCγ Phospholipase C gamma 1 27793011, 29327067 PTHLH Parathyroid hormone like hormone 27793011

DKK1 Dickkopf WNT signaling pathway inhibitor 1 19963132

TGFβR2 Transforming growth factor beta receptor 2 19963132 TNFAIP3 TNF alpha induced protein 3 28810605

Dab2 DAB2, clathrin adaptor protein 27919278, 27647909

EIF4EBP1 Eukaryotic translation initiation factor 4E binding protein 1 25892549, 20525238

BRD3 Bromodomain containing 3 28075468

UBAP1 Ubiquitin associated protein 1 20053927

JNK2 Mitogen-activated protein kinase 9 20053927

MTA2 Metastasis associated 1 family member 2 20053927

IκBα NFKB inhibitor alpha 28652762 TP53INP1 Tumor protein p53 inducible nuclear protein 1 26718506

HDGF Heparin binding growth factor 26252115

SHP-1 Protein tyrosine phosphatase, non-receptor type 6 29616111

MIIP Migration and invasion inhibitory protein 26081980, 26781335

IL-8 C-X-C motif chemokine ligand 8 29805670

FSCN1 Fascin actin-bundling protein 1 26314966, 26530812, 26304234, 25970784

SPARC Secreted protein acidic and cysteine rich 26503504

COL3A1 Collagen type III alpha 1 chain 25786138, 18085523

DNMT3a DNA methyltransferase 3 alpha 25786138

FIH1 Hypoxia inducible factor 1 subunit alpha inhibitor 26975503

MCM2 Minichromosome maintenance complex component 2 25098679

IGF1R Insulin like growth factor 1 receptor 25098679

BACH2 BTB domain and CNC homolog 2 29805566

GLI3 GLI family zinc finger 3 28487475

ADAM17 ADAM metallopeptidase domain 17 23895853, 29066913

CCNE2 Cyclin E2 26297956

MTA1 Metastasis associated 1 28350089

WNT2B Wnt family member 2B 28631568

LASP1 LIM and SH3 protein 1 25297925

MAFB MAF bzip transcription factor B 28982387

BRMS1 BRMS1, transcriptional repressor and anoikis regulator 26055874, 28000885

RAB14 RAB14, member RAS oncogene family 27501413

NRF1 Nuclear respiratory factor 1 [Homo sapiens 25201065, 29721083

TFAM Transcription factor A, mitochondrial 26201446, 21803736

FOXQ1 Forkhead box Q1 26201446

TUSC2 Tumor suppressor 2, mitochondrial calcium regulator 25856555

ARHGAP5 Rho gtpase activating protein 5 28781619

RAC1 Rac family small gtpase 1 25961434

BORF2 Ribonucleotide reductase subunit 1 24877689, 27243897

MDS1-EVI1 MDS1 and EVI1 complex locus 7698877

CCDC170 Coiled-coil domain containing 170 24615621

RB2/p130 RB transcriptional corepressor like 2 24615621

HSP70-2 Heat shock protein family A (Hsp70) member 1A 10646842

HIF-1α Hypoxia inducible factor 1 subunit alpha 23667540, 12691826 PKC Proline rich transmembrane protein 2 25733830, 28057028, 27567526, 28398871, 24335623

Nanog Nanog homeobox 23536578, 25823923

BART ADP ribosylation factor like gtpase 2 binding protein 23536578

NOR1 Nuclear receptor subfamily 4 group A member 3 27147748

HSF1 Heat shock transcription factor 1 21803736

IGFR Insulin like growth factor 1 receptor 21803736

PRAS40 AKT1 substrate 1 27883284

TWIST Twist family bhlh transcription factor 1 27883284

XBP1 X-box binding protein 1 [Homo sapiens 27883284

RRM2 Ribonucleotide reductase regulatory subunit M2 27883284

TIF2 Nuclear receptor coactivator 2 28906488

KLF4 Kruppel like factor 4 22581837

NES Nestin 29973197

PDRG1 P53 and DNA damage regulated 1 29973197

S1P Membrane bound transcription factor peptidase, site 1 28057028

S1PR3 Sphingosine-1-phosphate receptor 3 28240350

Twist1 Twist family bhlh transcription factor 1 28240350

OPCML Opioid binding protein/cell adhesion molecule like 27793033

AKR1B10 Aldo-keto reductase family 1 member B10 18714356

SATB1 SATB homeobox 1 26835713

BCAT1 Branched chain amino acid transaminase 1 24047082, 24696710

FOXM1 Forkhead box M1 23758864 fascin-1 Fascin actin-bundling protein 1 25231007, 28277541 paxillin Paxillin 25231007

TRIAP1 TP53 regulated inhibitor of apoptosis 1 25231007

NgR3 Reticulon 4 receptor like 1 27428374

Wip1 Protein phosphatase, Mg2+/Mn2+ dependent 1D 29327067

ABL ABL proto-oncogene 1, non-receptor tyrosine kinase 25060857 p53R2 Ribonucleotide reductase regulatory TP53 inducible subunit M2B 29914565

PARP1 Poly(ADP-ribose) polymerase 1 29237424

PBK PDZ binding kinase [Homo sapiens 23979918

WEE1 WEE1 G2 checkpoint kinase 27049917

APP Amyloid beta precursor protein 26025928

XRCC2 X-ray repair cross complementing 2 26773938

TTP ZFP36 ring finger protein 27356695

PUM2 Pumilio RNA binding family member 2 27567526

NESG1 Cilia and flagella associated protein 45 27567526

ATF2 Glial cell derived neurotrophic factor 22140479

MAPKAPK2 Mitogen-activated protein kinase-activated protein kinase 2 22140479

GRB2 Growth factor receptor bound protein 2 22140479, 24056810

DUSP3 Dual specificity phosphatase 3 22140479

ZNF24 Zinc finger protein 24 22140479

IDO Indoleamine 2,3-dioxygenase 1 28968968

KiSS-1 Kiss-1 metastasis suppressor 26608400

AXOR12 KISS1 receptor 24254791

RKIP Phosphatidylethanolamine binding protein 1 24254791

DLC-1 DLC1 Rho gtpase activating protein 27647315, 25915430

HRASLS HRAS like suppressor 23908159

RARRES1 Retinoic acid receptor responder 1 17689134

RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 17689134

SLIT2 Slit guidance ligand 2 22487779

EDNRB Endothelin receptor type B 29107007

DLEC1 DLEC1, cilia and flagella associated protein 11920632

SOX11 SRY-box 11 23790641

NEDD8 Neural precursor cell expressed, developmentally down-regulated 8 24188789

ICAM-1 Intercellular adhesion molecule 1 28569775

PCDH8 Protocadherin 8 25857718

PCDH20 Protocadherin 20 22273848

H-ras Hras proto-oncogene, gtpase 25736877

RBMS3 RNA binding motif single stranded interacting protein 3 20584693

FGFR3 Fibroblast growth factor receptor 3 22957092, 25588924, 22360856

TACC3 Transforming acidic coiled-coil containing protein 3 25535896

H19 H19, imprinted maternally expressed transcript 25535896

HoxC8 Homeobox C8 12569573

RERG RAS like estrogen regulated growth inhibitor 25745994

RhoE Rho family gtpase 3 28659184

MRP1 ATP binding cassette subfamily C member 1 24376145

SDF-1α C-X-C motif chemokine ligand 12 24376145 CXCR4 C-X-C motif chemokine receptor 4 28559386

RPA3 Replication protein A3 28559386

RSF1 Remodeling and spacing factor 1 28557284

S100A4 S100 calcium binding protein A4 28261335

S100A6 S100 calcium binding protein A6 26292668

SAA1 Serum amyloid A1 27596819

BNLF2a Protein BNLF2a 24608426

USP22 Ubiquitin specific peptidase 22 25959517

LOX Lysyl oxidase 25482932

CA9 Carbonic anhydrase 9 25520868

VAV2 Vav guanine nucleotide exchange factor 2 25520868

WASL Wiskott-Aldrich syndrome like 25277193

ROCK1 Rho associated coiled-coil containing protein kinase 1 25277193

USF1 Upstream transcription factor 1 25277193

TIG1 G protein-coupled receptor class C group 5 member A 25277193

SATB1 SATB homeobox 1 15455391

Mcl-1 MCL1, BCL2 family apoptosis regulator 24696710

SOX1 SRY-box 1 28696828

Sp3 Sp3 transcription factor 25427424

CENPH Centromere protein H 22682030

TNF β Lymphotoxin alpha 22682030 STYK1 Serine/threonine/tyrosine kinase 1 26198046

RelB RELB proto-oncogene, NF-kb subunit 28720063

NF-kb2 Nuclear factor kappa B subunit 2 28452850

TAP1 Transporter 1, ATP binding cassette subfamily B member 28452850

ANXA2 Annexin A2 17498556

CPT1A Carnitine palmitoyltransferase 1A 26196246

TFAP2A Transcription factor AP-2 alpha 29721083

TFPI-2 Tissue factor pathway inhibitor 2 24335623

FLIP CASP8 and FADD like apoptosis regulator 21062455

CYP2E1 Cytochrome P450 family 2 subfamily E member 1 20224598

IL-16 Interleukin 16 25481674

BFRF1 Nuclear egress membrane protein 24101193

IRF6 Interferon regulatory factor 6 10708440

ABCG2 ATP binding cassette subfamily G member 2 29111349

NLK Glucose-6-phosphate isomerase 29111349

BHRF1 Apoptosis regulator BHRF1 28543390

NADPH 2,4-dienoyl-coa reductase 1 9742281

IKBKB Inhibitor of nuclear factor kappa B kinase subunit beta 27243897

FOXC1 Forkhead box C1 28445979

MKK4 Mitogen-activated protein kinase kinase 4 28635400

ARHGEF3 Rho guanine nucleotide exchange factor 3 21702039

BIRC8 Baculoviral IAP repeat containing 8 27028992

GADD45G Growth arrest and DNA damage inducible gamma 27028992 p14 Cyclin dependent kinase inhibitor 2A 16166418

TIMELESS Timeless circadian regulator 20395212

SOX-5 SRY-box 5 28583847

BRD7 Bromodomain containing 7 18085523

TBL1XR1 Transducin beta like 1 X-linked receptor 1 19111069

BCSC-1 Von Willebrand factor A domain containing 5A 25145705

GNAT1 G protein subunit alpha transducin 1 19656157

LARS2 Leucyl-trna synthetase 2, mitochondrial 22360856

CHL1 Cell adhesion molecule L1 like 22360856

LTF Lactotransferrin 22360856

UBE2T Ubiquitin conjugating enzyme E2 T 22360856, 21400573

AFAP1 Actin filament associated protein 1 26943030 p70S6K Ribosomal protein S6 kinase B1 26246469

4E-BP1 Eukaryotic translation initiation factor 4E binding protein 1 26872369

LDLRAP1 Low density lipoprotein receptor adaptor protein 1 26872369

PHF20 PHD finger protein 20 22986368

LUC7L3 LUC7 like 3 pre-mrna splicing factor 22986368

MST1R Macrophage stimulating 1 receptor 22986368

CYLD CYLD lysine 63 deubiquitinase 26951679

WNT1 Wnt family member 1 27647909

XBP-1 X-box binding protein 1 25980501

YPEL3 Yippee like 3 17494074

Sam68 KH RNA binding domain containing, signal transduction associated 1 27400785

FOXO3 Forkhead box O3 23443784

CCDC19 Cilia and flagella associated protein 45 23443784

CXCL10 C-X-C motif chemokine ligand 10 22931604

PTGS2 Prostaglandin-endoperoxide synthase 2 23174573

MALAT1 Metastasis associated lung adenocarcinoma transcript 1 23174573

HDAC6 Histone deacetylase 6 23688988

LIMK1 LIM domain kinase 1 24771510, 24156782