Clinical Prevention Services Tel 604.707.5600 Provincial STI/HIV Clinic Fax 604.707.5604

655 West 12th Avenue www.bccdc.ca Vancouver, BC V5Z 4R4 www.SmartSexResource.com

Ceftriaxone Ceftriaxone is an antibiotic given by injection into a muscle for the treatment of certain sexually transmitted infections (STI).

Allergies • Tell your healthcare provider if you have a history of an anaphylactic allergy or immediate reaction to any penicillin antibiotic such as penicillin V-K, amoxicillin (Amoxil®) or any cephalosporin antibiotic such as cefixime (Suprax®), ceftriaxone (Rocephin®) • Tell your healthcare provider if you have an allergy to lidocaine, or other local anesthetics of the amide type e.g. prilocaine (lidocaine is mixed with ceftriaxone to reduce pain at the injection site).

Pregnancy and Chest/Breastfeeding Ceftriaxone may be used with caution during pregnancy and chest/breastfeeding. Please consult your healthcare provider.

CAUTION • Drug Interactions: Tell your healthcare provider if you are taking any prescription, non-prescription, herbal, or recreational products. Not all individual drug interactions are listed in this document.

• Tell your healthcare provider if you have any gallbladder, liver, kidney, pancreas or bleeding disorder, or a history of stomach dysfunction, particularly colitis. • Do not take the following medications with ceftriaxone: Oral Typhoid vaccine (Vivotif®) o  • Ceftriaxone may interfere with certain urine glucose tests. (Clinitest ) • Ceftriaxone is contraindicated in preterm newborns or infants less than one month old with high blood levels of bilirubin.

Side Effects • You may experience discomfort, redness or swelling at the injection site. • You may experience skin rash or diarrhea. • If any of these effects persist or worsen, please contact your healthcare provider.

Last Reviewed by BCCDC Pharmacy April 2019 Page 1 of 2

Ceftriaxone (cont’d)

Care Following Treatment • Please wait in the clinic 15 minutes after your injection. • If you have any reaction following treatment (e.g., rash, itchiness, difficulty breathing), please inform a staff member immediately. • If these symptoms occur after leaving the clinic, please seek emergency medical help immediately.

Special Instructions • Do not have sex until: o One week after you complete your treatment of ceftriaxone, and o One week after your sex partner(s) have completed their treatments, even if their test results are negative. • You will need retreatment if you have sex with an untreated partner, or if you have sex before either you or your partner’s treatment period is complete. Please discuss with your healthcare provider.

If you have any questions or need more information, please visit www.smartsexresource.com or contact your healthcare provider.

Last Reviewed by BCCDC Pharmacy April 2019 Page 2 of 2