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1 Eddie Gerba
Eddie Gerba (PhD) European Institute London School of Economics Houghton Street, London WC2A 2AE Phone: +44-759-5960988/+34-666-70-30-17 E-mail: [email protected] EMPLOYMENT PROFILE ADVISORY AND CENTRAL BANK EXPERIENCE Banco de España (Central Bank of Spain), Madrid, Spain Sep 14 – present Senior Research Economist in DG Financial Stability Jul 16 - present Achievements: • Lead expert in the Department on structural modelling, macro-financial linkages and financial frictions. Advising the management and conducting research in these areas. • Chair/leader of two pan-European expert groups on macroprudential policy and financial stability analysis: Co-chair of the Task Force on Cross-border Spill-over Analysis of Macroprudential Policy (ESCB) and Leader of the Research Team in the Expert Group on Structural Capital Buffers (ESRB). • Spanish representative in the Working Group on Methodologies for Analysis of Real Estate Markets (ESRB). • Conducting policy-relevant research in multiple areas of macroprudential policy: Optimal capital-based instruments, optimal macroprudential policy mix and joint impact assessment, design and structural impact assessment of distinct measures, including: CCyB, G-SIIs/O-SIIs, LTVs, LTIs, dynamic provisioning, role of expectations and timing in implementation of macroprudential policy. • Writing reports and advising on various contemporary issues related to ESRB/ECB/Basel policies and discussions, including cross-border banking, reciprocity in macroprudential policies, interactions between macroprudential measures, structural capital buffers, real estate risks, dynamics in real-estate markets, sovereign debt risk-weights, and credit growth. Visiting Research Fellow in DG Economics and Statistics Sep 14 – Sep 15 Achievements: • Based in the Department of Macroeconomics and Forecasting. -
For Young Scientists
THE BLAVATNIK AWARDS For Young Scientists N E R AT I O N O T G E F S C E X I E N N T E I F H I C T G I N I N N V O I V R A D T I O N 2021 The Blavatnik Awards for Young Scientists honor exceptional young scientists and engineers by celebrating their extraordinary achievements, recognizing outstanding promise, and accelerating innovation through unrestricted funding. Table of Contents Key Features ..............................................................................................................................................4 Our History ................................................................................................................................................6 Blavatnik Regional Awards ...................................................................................................................8 Blavatnik National Awards .................................................................................................................10 Blavatnik Awards in the United Kingdom ......................................................................................12 Blavatnik Awards in Israel................................................................................................................... 14 Blavatnik Science Scholars ................................................................................................................. 16 In the News ............................................................................................................................................. 18 -
Anew Drug Design Strategy in the Liht of Molecular Hybridization Concept
www.ijcrt.org © 2020 IJCRT | Volume 8, Issue 12 December 2020 | ISSN: 2320-2882 “Drug Design strategy and chemical process maximization in the light of Molecular Hybridization Concept.” Subhasis Basu, Ph D Registration No: VB 1198 of 2018-2019. Department Of Chemistry, Visva-Bharati University A Draft Thesis is submitted for the partial fulfilment of PhD in Chemistry Thesis/Degree proceeding. DECLARATION I Certify that a. The Work contained in this thesis is original and has been done by me under the guidance of my supervisor. b. The work has not been submitted to any other Institute for any degree or diploma. c. I have followed the guidelines provided by the Institute in preparing the thesis. d. I have conformed to the norms and guidelines given in the Ethical Code of Conduct of the Institute. e. Whenever I have used materials (data, theoretical analysis, figures and text) from other sources, I have given due credit to them by citing them in the text of the thesis and giving their details in the references. Further, I have taken permission from the copyright owners of the sources, whenever necessary. IJCRT2012039 International Journal of Creative Research Thoughts (IJCRT) www.ijcrt.org 284 www.ijcrt.org © 2020 IJCRT | Volume 8, Issue 12 December 2020 | ISSN: 2320-2882 f. Whenever I have quoted written materials from other sources I have put them under quotation marks and given due credit to the sources by citing them and giving required details in the references. (Subhasis Basu) ACKNOWLEDGEMENT This preface is to extend an appreciation to all those individuals who with their generous co- operation guided us in every aspect to make this design and drawing successful. -
Issue 253 ▸ 1 November 2012 Reportersharing Stories of Imperial’S Community
Issue 253 ▸ 1 November 2012 reporterSharing stories of Imperial’s community fringe benefits Visitors to the first Imperial Fringe take things to heart as they get to grips with our research → centre pages £35 MILLION FORWARD LONDON AWARD FOR THINKING BIKEATHON IMPERIAL Dr Simon Professor Dazzi HEFCE support Schultz on the on cycling 95 for Imperial value of looking miles with his West to the future patient PAGE 3 PAGE 7 PAGE 12 2 >> newsupdate www.imperial.ac.uk/reporter | reporter | 1 November 2012 • issue 253 Researchers unite to open up about animal research EDITOR’S CORNER Imperial has joined medical charities, remain high overall, with 66 per cent research funders, the pharmaceuti- of people supporting animal experi- cal industry and other universities mentation for medical research, Pregnant in signing a declaration for greater 40 per cent want to know more openness on animal research fol- before they form a firm opinion. pause lowing signs of a decrease in public Professor Maggie Dallman, “I hope this declaration will give s upport for animal research. Principal of the Faculty of Natural organisations and scientists the con- The results of a recent Ipsos Sciences, said: “Animal research fidence to speak out with the support As a number of you might Mori poll commissioned by the is a small but vital part of scientific of the wider research community.” know this is my final government reveal a 10 percentage and medical research in the UK. Ter- The declaration was signed by issue of Reporter before point decrease in public support for rorist activity by animal extremists in more than 40 research organisations, I go on maternity leave. -
Introduction
Cambridge University Press 978-1-107-14759-1 - The Uk Economy in the Long Expansion and its Aftermath Edited by Jagjit S. Chadha, Alec Chrystal, Joe Pearlman, Peter Smith and Stephen Wright Excerpt More information Introduction Jagjit S. Chadha, Alec Chrystal, Joe Pearlman, Peter Smith and Stephen Wright In the aftermath of the inflation and recessions of the 1970s and early 1980s, from the early 1990s onwards there was a major upswing in most advanced countries. In the UK it was the longest period of eco- nomic expansion on record. But it came to an abrupt end in 2007, with the freezing of the interbank markets and the collapse of Northern Rock, followed in 2008 by Bear Stearns and Lehman Brothers. Before the crisis, many economists had begun to call this period of upswing the Great Moderation; and, echoing developments in other disciplines, such as political thought, some openly wondered whether we had found the answer to the questions that had perennially been posed by ‘boom and bust’. But given the magnitude of the shocks that hit the global economy in the crisis period of 2007–08 (and since then in a number of countries) the apparent reduction in macroeconomic volatility of the earlier period now appears, with the benefit of hindsight, to have been largely illusory. We therefore argue that the period 1992–2007 can more accurately (and less ambitiously) be described as the Long Expansion – hence the title of this volume. It is now clear that many of the problems that have occupied policy- makers during the global financial crisis were being incubated during this period. -
Epigenetic Therapeutics in Malaria
Epigenetic therapeutics in malaria: A chemical biological approach towards the validation of histone lysine methyltransferase inhibition in Plasmodium falciparum Alexandra Lubin PhD Thesis Supervisor: Dr Matthew Fuchter Department of Chemistry, Imperial College London March 2018 Declaration of Originality I confirm that the work presented within this thesis is entirely my own, conducted under the supervision of Dr Matthew J. Fuchter, at the Department of Chemistry, Imperial College London, unless otherwise stated. All work performed by others has been acknowledged within the text and referenced where appropriate. Copyright Declaration The copyright of this thesis rests with the author and is made available under a Creative Commons Attribution Non-Commercial No Derivatives licence. Researchers are free to copy, distribute or transmit the thesis on the condition that they attribute it, that they do not use it for commercial purposes and that they do not alter, transform or build upon it. For any reuse or redistribution, researchers must make clear to others the licence terms of this work. 2 Abstract A growing threat from drug resistance means there is an urgent need for new therapeutics and novel mechanisms of action for antimalarial drug discovery. Epigenetic mechanisms, including histone methylation, are vital throughout the Plasmodium lifecycle, and could provide exciting new targets. BIX-01294 and a series of diaminoquinazolines are putative Plasmodium histone lysine methyltransferase inhibitors, with exciting antimalarial properties, although robust evidence for their molecular targets is lacking. To this end, a well-developed SAR for this series allowed for the development of small-molecule photo-crosslinkable probes to investigate the targets. These probes effectively label Plasmodium falciparum lysates and show similarities with the target profiles of BIX-01294 and the diaminoquinazoline series. -
Diamond-II | Advancing Science Diamond-II: Advancing Science
Diamond-II | Advancing Science Diamond-II: Advancing Science Contents 1. Executive summary 2 7.3.1. Catalysis 51 2. Background 4 In situ experiments at the micro and 3. The Diamond-II synchrotron 6 nanoscales 52 An increased sensitivity to ligands with 4. Beamlines and complementary spatial resolution 53 technologies 9 New paradigms at the nanoscale 53 4.1. Benefit of Diamond-II for existing ID Biocatalysis 54 beamlines 9 Catalyst characterisation: combination of 4.2. Optimising existing instruments using techniques and using external triggers 54 new mid section straights 10 7.3.2. Advanced materials 55 4.3. New instruments 12 Porous materials 55 4.4. Development of complementary technologies 12 Metal-Organic Frameworks 55 5. The purpose of this document 14 Probing kinetic correlations in space and time 56 6. Diamond-II: Advancing life sciences 16 7.3.3. Formulation 57 6.1. Life science challenges 16 Electronic structure of in situ nucleation 6.2. Integrated structural biology 18 of organic solutes 58 6.2.1. Chromosome structure 19 7.4. Quantum materials 62 6.2.2. The prokaryotic cell surface 20 7.4.1. Designing and controlling quantum materials 62 6.2.3. Membrane proteins 20 7.4.2. Inhomogeneity and emergence in 6.2.4. Dynamic studies 20 quantum materials 63 6.3. Biotechnology and biological systems 24 7.4.3. Controlling emergence using phase 6.3.1. Engineering and applications of separation 64 biomaterials 24 7.4.4. A new dimension for magnetism 64 6.3.2. Biological systems imaging 26 7.4.5. Tuning coupled ferroic order 66 6.4. -
THE BLAVATNIK AWARDS for Young Scientists
THE BLAVATNIK AWARDS For Young Scientists N E R AT I O N O T G E F S C E X I E N N T E I F H I C T G I N I N N V O I V R A D T I O N 2020 The Blavatnik Awards for Young Scientists honor exceptional young scientists and engineers by celebrating their extraordinary achievements, recognizing outstanding promise, and accelerating innovation through unrestricted funding. Table of Contents Key Features ..............................................................................................................................................4 Our History ................................................................................................................................................6 Blavatnik Regional Awards ...................................................................................................................8 Blavatnik National Awards .................................................................................................................10 Blavatnik Awards in the United Kingdom ......................................................................................12 Blavatnik Awards in Israel................................................................................................................... 14 Blavatnik Science Scholars ................................................................................................................. 16 In the News ............................................................................................................................................. 18 -
Nyas-2000-Magazine-Spring-2020.Pdf
SPECIAL ANNOUNCEMENT: COVID-19 RESOURCES p5 THE NEW YORK ACADEMY OF CIENCES SMAGAZINE • SPRING 2020 SO BLE LUTI A ON IN S TA F S O U R S T E H L E B W A OR R T LD’S DINNE A look at challenges and opportunities in food and nutrition science research. WWW.NYAS.ORG BOARD OF GOVERNORS 2019-2020 Current as of September 18, 2019 CHAIR Functions, Governance & Seema Kumar, Vice Pres- Lowell Robinson, Corporate Nadav Zafrir, Co-Founder, Resilience Centre, Chairman Hon. Jerry MacArthur Compliance, PepsiCo ident of Innovation, Global Director and Advisor; serves Chief Executive Officer, of the EAT Advisory Board Hultin, Chair and Co-Founder Jacqueline Corbelli, Health and Science Policy as Director of Aratana TEAM8, Inc. Paul Stoffels, Vice Chair of of Global Futures Group, LLC Chairman, CEO and Communication for Johnson Therapeutics INTERNATIONAL BOARD the Executive Committee VICE-CHAIR Co-Founder, BrightLine & Johnson Konstantin Shakhnovich, OF GOVERNORS and Chief Scientific Officer, Thomas Pompidou, Founder Mikael Dolsten, President, R. May Lee, Global thought former Goldman Sachs Seth F. Berkley, Chief Johnson & Johnson and Partner at Marker, LLC Worldwide Research and leader on innovation/digital Partner, Head of Systematic Executive Officer, The Global CHAIRS EMERITI TREASURER Development; Senior Vice transformation, education Market-Making (retired) Alliance for Vaccines and John E. Sexton, Former Pres- Laura Sachar, Managing President, Pfizer Inc and gender workplace issues Peter Thorén, Executive Immunization ident, New York University Partner and Co-Founder, MaryEllen Elia, Senior Fellow, Pablo Legorreta, Founder Vice President, Access Stefan Catsicas, Chief Tech- Torsten N. Wiesel, StarVest Partners International Center for Lead- and CEO, Royalty Pharma Industries nology Officer Nestlé S.A. -
Dynamic Macroeconomic Analysis: Theory and Policy in General Equilibrium Edited by Sumru Altug, Jagjit S
Cambridge University Press 978-0-521-53403-1 - Dynamic Macroeconomic Analysis: Theory and Policy in General Equilibrium Edited by Sumru Altug, Jagjit S. Chadha and Charles Nolan Frontmatter More information DYNAMIC MACROECONOMIC ANALYSIS Dynamic stochastic general equilibrium (DSGE) models have begun to dominate the field of macroeconomic theory and policy-making. These models describe the evolution of macroeconomic activity as arecursive sequence of outcomes based upon the optimal decision rules of rational households, firms and policy-makers. While posing a micro-founded dynamic optimisation problem for agents under uncertainty, such models have been shown to be both analytically tractable and sufficiently rich for meaningful policy analysis in a wide class of macroeconomic problems, for example, monetary and fiscal policy, economic cycles and growth and capital flows. This volume collects specially commissioned papers from leading researchers, which pull together some of the key recent results in diverse areas. This book promotes research using optimising models and will inform researchers, postgraduate students and economists in policy-oriented organisations of some of the key findings and policy implications. Sumru Altug is Professor at Koc University, Turkey. She is the joint author of Dynamic Choice and Asset Markets (with Pamela Labadie) (1995). Jagjit S. Chadha is Professor of Economics at the University of St Andrews. Formerly fellow of Clare College, Cambridge and lecturer at Cambridge University. Charles Nolan is Reader in Economics at the University of Durham. © in this web service Cambridge University Press www.cambridge.org Cambridge University Press 978-0-521-53403-1 - Dynamic Macroeconomic Analysis: Theory and Policy in General Equilibrium Edited by Sumru Altug, Jagjit S. -
MMF Economic Policy Seminar: 6Th June 2014 Hosted: School of Economics and Finance Queen Mary University of London
MMF Economic Policy Seminar: 6th June 2014 Hosted: School of Economics and Finance Queen Mary University of London Monetary and Fiscal Issues for an Independent Scotland Venue: The David Sizer Lecture Theatre, Francis Bancroft Building 13.00 – 14.00 Registration 14:00 – 15:30 Session I Alun Evans (Scotland Office) Angus Armstrong (NIESR) David Bell (Stirling) Chair: Francis Breedon 15.30 – 16:00 – Tea/Coffee 16:00 – 17:30 Session II Nick Macpherson (HMT) Ronald MacDonald (Glasgow) Andrew Hughes-Hallett (Georgetown and St Andrews) Chair: Jagjit Chadha Organisers: Angus Armstrong (NIESR) Francis Breedon (QMUL), Jagjit Chadha (Kent and MMF), Georgios Chortoreas (Kings College London and MMF), Haroon Mumtaz (QMUL) and Kevin Sheedy (LSE and MMF). MMF Economic Policy Seminar - Spring 2014 Hosts: School of Economics and Finance, Queen Mary University of London Interest Rate Normalisation Date: Friday 21 February 2014 Venue: The David Sizer Lecture Theatre, Ground Floor of Francis Bancroft Building, Queen Mary, University of London, Mile End Road, London E1 4NS Programme: 13:00-14:00 Lunch in Francis Bancroft foyer. 14:00-15:30 Session I Martin Weale (MPC, Bank of England and QMUL) “Forward Guidance and its Effects”. Bill Allen (Cass) “The next reactivation of monetary policy” Shamik Dahr (Aviva Investors and MMF) “What is normal, anyway?” 15:30-16:00 Coffee break 16:00-17:30 Session II Simon Wren Lewis (Oxford) "The idea of secular stagnation is fashionable, but does it make sense?” Alex Michaelides (Imperial) "Policy lessons from Cyprus" Richard Barwell (RBS Capital Markets) "Interest rate normalisation: a markets perspective” 17:30 End of Seminar - Drinks Reception in the foyer. -
Next Generation 'Frustrated Lewis Pairs'
NEXT GENERATION ‘FRUSTRATED LEWIS PAIRS’ by Daniel J. Scott A dissertation submitted to the Department of Chemistry of Imperial College London for the degree of Doctor of Philosophy December 2016 1 Abstract The past decade has seen the emergence of a new concept in main-group chemistry: ‘frustrated Lewis pairs’ (FLPs) are combinations of a Lewis acid (LA) and base (LB) that are prevented from forming the classically-expected adduct. By displaying simultaneously acidic and basic behaviour, these systems have been shown to be capable of activating a wide range of chemical bonds, in a manner highly reminiscent of transition-metal (TM) compounds. Chief among these reactions is the activation of H2, which can then be transferred from the FLP to an appropriate substrate. FLPs have thus provided an entirely new class of homogeneous hydrogenation catalysts, which do not require the use of TMs. Nevertheless, prior to the work described herein, such catalysis had not been successfully applied to the hydrogenation of organic carbonyl functional groups, and had been found to be extremely sensitive to the presence of moisture. This thesis describes work that has successfully overcome these limitations. Chapter 1 provides an introduction to the field of FLP chemistry, including a general summary of the topic, and a more detailed overview of catalytic hydrogenation mediated by FLPs. Chapter 2 describes the development of novel FLPs based on the combination of strong triarylborane LAs and weak ethereal solvent LBs. These systems are shown to be highly effective for the hydrogenation of a variety of substrates, including the first examples of both FLP-catalysed hydrogenation of ketones and aldehydes, and moisture-tolerant FLP-catalysed hydrogenation.