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Table of Contents CONTENTS 1. Specimen evaluation 1 Specimen Type. 1 Clinical History. 1 Radiologic Correlation . 1 Special Studies . 1 Immunohistochemistry . 2 Electron Microscopy. 2 Genetics. 3 Recognizing Non-Soft Tissue Tumors. 3 Grading and Prognostication of Sarcomas. 3 Management of Specimen and Reporting. 4 2. Nonmalignant Fibroblastic and Myofibroblastic Tumors and Tumor-Like Lesions . 7 Nodular Fasciitis . 7 Proliferative Fasciitis and Myositis . 12 Ischemic Fasciitis . 18 Fibroma of Tendon Sheath. 21 Nuchal-Type Fibroma . 24 Gardner-Associated Fibroma. 27 Desmoplastic Fibroblastoma. 27 Elastofibroma. 34 Pleomorphic Fibroma of Skin. 39 Intranodal (Palisaded) Myofibroblastoma. 39 Other Fibroma Variants and Fibrous Proliferations . 44 Calcifying Fibrous (Pseudo)Tumor . 47 Juvenile Hyaline Fibromatosis. 52 Fibromatosis Colli. 54 Infantile Digital Fibroma/Fibromatosis. 58 Calcifying Aponeurotic Fibroma. 63 Fibrous Hamartoma of Infancy . 65 Myofibroma/Myofibromatosis . 69 Palmar/Plantar Fibromatosis. 80 Lipofibromatosis. 85 Diffuse Infantile Fibromatosis. 90 Desmoid-Type Fibromatosis . 92 Benign Fibrous Histiocytoma (Dermatofibroma). 98 xi Tumors of the Soft Tissues Non-neural Granular Cell Tumor. 104 Neurothekeoma . 104 Plexiform Fibrohistiocytic Tumor. 110 Superficial Acral Fibromyxoma . 113 Superficial Angiomyxoma (Cutaneous Myxoma). 118 Intramuscular Myxoma. 125 Juxta-articular Myxoma. 128 Aggressive Angiomyxoma . 128 Angiomyofibroblastoma. 135 Cellular Angiofibroma. 136 3. Fibroblastic/Myofibroblastic Neoplasms with Variable Biologic Potential. 165 Solitary Fibrous Tumor . 165 Dermatofibrosarcoma Protuberans. 169 Giant Cell Fibroblastoma . 177 Low-Grade Fibromyxoid Sarcoma. 181 Sclerosing Epithelioid Fibrosarcoma . 185 Inflammatory Myofibroblastic Tumor. 186 Inflammatory Myxohyaline Tumor of Distal Extremities (Acral Myxoinflammatory Fibroblastic Sarcoma). 190 Infantile Fibrosarcoma (Congenital Fibrosarcoma) . 192 Adult Fibrosarcoma and Myofibroblastic Sarcoma . 193 Myxofibrosarcoma. 196 Malignant Fibrous Histiocytoma/Undifferentiated Pleomorphic Sarcoma . 203 Pleomorphic Hyalinizing Angiectatic Tumor. 209 Giant Cell Tumor of Soft Parts and Giant Cell Malignant Fibrous Histiocytoma . 210 4. Lipomatous Tumors. 223 Lipoma and Variants . 223 Ordinary Lipoma. 224 Lipoma with Metaplastic Cartilage and Bone. 226 Lipomatosis of the Nerve . 226 Angiolipoma. 227 Spindle Cell Lipoma and Pleomorphic Lipoma. 229 Chondroid Lipoma. 233 Hemosiderotic Fibrohistiocytic Lipomatous Lesion/Tumor . 235 Hibernoma. 236 Lipoblastoma . 238 Massive Localized Lymphedema in the Obese . 240 Liposarcoma. 240 Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma. 240 xii Contents Dedifferentiated Liposarcoma . 248 Spindle Cell Liposarcoma. 254 Myxoid Liposarcoma. 254 Pleomorphic Liposarcoma. 259 5. Smooth Muscle Tumors. 271 Angioleiomyoma . 271 Myopericytoma . 271 Glomus Tumor. 274 Estrogen Receptor-Positive Smooth Muscle Tumors in Women. 275 Epstein-Barr Virus–Associated Smooth Muscle Tumors . 279 Leiomyosarcoma. 282 6. Tumors with Skeletal Muscle Differentiation. 289 Rhabdomyomatous Mesenchymal Hamartoma . 289 Rhabdomyoma . 290 Rhabdomyosarcoma . 291 Embryonal Rhabdomyosarcoma . 292 Alveolar Rhabdomyosarcoma. 298 Pleomorphic Rhabdomyosarcoma . 301 Sclerosing Rhabdomyosarcoma. 303 7. Vascular Tumors. 309 Papillary Endothelial Hyperplasia. 309 Hemangiomas. 309 Capillary Hemangioma . 311 Cavernous Hemangioma. 311 Venous Hemangioma. 311 Microvenular Hemangioma . 312 Intramuscular Hemangioma . 312 Cutaneous Arteriovenous Hemangioma. 312 Epithelioid Hemangioma . 315 Glomeruloid Hemangioma . 320 Hobnail Hemangioma. 323 Juvenile Capillary Hemangioma . 324 Lobular Capillary Hemangioma. 324 Spindle Cell Hemangioma. 326 Tufted Hemangioma. 328 Verrucous Hemangioma. 330 Lymphangioma (Lymphatic Malformation). 331 Lymphangiomatosis . ..
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