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SINGAPORE 2016

17 - 22 JANUARY 2016

SPEAKERS AND YOUNG SCIENTISTS DIRECTORY

ADVANCING SCIENCE, CREATING TECHNOLOGIES FOR A BETTER WORLD TABLE OF CONTENTS

Speakers 3

Young Scientists Index 48

Young Scientists Directory 54

International Advisory Committee 145 SPEAKERS SPEAKERS SPEAKERS

NOBEL PRIZE

Prof Prof Arieh Warshel Prof Cédric Villani Prof Stephen Smale Chemistry (2009) Chemistry (2013) Fields Medal (2010) Fields Medal (1966)

Prof Ei-ichi Negishi Sir Anthony Leggett MILLENIUM TECHNOLOGY PRIZE Chemistry (2010) (2003)

Prof Michael Grätzel Prof Stuart Parkin Prof Prof Millennium Technoly Prize (2010) Millennium Technology Award (2014) Physics (1984) Physics (2004)

TURING AWARD Prof Gerard ’t Hooft Prof Jerome Friedman Physics (1999) Physics (1990) Prof Dr (2000) Turing Award (2013) Prof Prof Physics (2012) or Medicine (2008) Prof Prof Richard Karp Turing Award (2010) Turing Award (1985) Prof John Sir Richard Roberts Physiology or Medicine (2005) Physiology or Medicine (1993)

Sir Physiology or Medicine (2001)

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When Professor Ada Yonath won the 2009 their ability to withstand high temperatures. At the time, others criticised in Chemistry for her discovery of her decision to work with the little known bacteria, but the discovery the structure of ribosomes, she not only raised of heat-stable enzymes which revolutionised molecular biology soon public interest in science but also inspired a silenced them. By the early 1980s, Prof Yonath was able to create the first greater appreciation for a head of curly hair. ribosome crystals, taking advantage of the unusually stable ribosomes During her Nobel banquet speech, Prof Yonath of her organism of choice. explained that curly hair, like her own, is now called “rosh male ribosomin” in , which Based on the understanding of ribosomal function she uncovered, translates to a head full of ribosomes. scientists can now explain how antibiotics act on bacteria, information that has been used in rational structure-based design for urgently ADA YONATH Ribosomes are cellular machines that are needed new classes of antibiotics. essential for synthesis, found in organisms from bacteria to humans. Even Aside from the intense scepticism that her work faced in the early (2009) though scientists understood what ribosomes days, Prof Yonath had to overcome several difficulties in her early life, did, no one yet knew how they worked. Their particularly following the death of her father when she was 11 years old. large size, complexity and instability made it With her mother in poor health and not very well educated, she found very difficult get them in the orderly crystalline herself shouldering responsibilities beyond her years, including looking form required for X-ray crystallography to after her younger sister. Nevertheless, her mother was supportive of her reveal their structure. education and saw her through her Master’s degree at the Hebrew University of Jerusalem. Although her initial attempts to crystallise ribosomes were fraught with technical Prof Yonath has received many international awards and honours, challenges, Prof Yonath persevered. Her including the Israel Prize in 2002, the Wolf Prize in Chemistry in 2006, the conviction that what others said was World Award of Science in 2008, and the L’Oreal-UNESCO impossible could be done was inspired in part Award for in 2008. In 2015, she was awarded honorary by the fact that hibernating polar bears have degrees from the Medical University of Lodz, De La Salle University in the highly organised ribosomes, something she Philippines and the Joseph Fourier University in . had read about by chance while recovering from a cycling accident.

Going from one extreme environment to another, Prof Yonath decided to work with Dead Sea bacteria, which were known for

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When the first 3D structure of a protein – he graduated summa cum laude with a bachelor of science degree myoglobin – was revealed in 1958, it was no in chemistry in 1996, he went on to earn a Master’s and Ph.D. degree more sophisticated than blobs of plasticine in chemical physics at the Weizmann Institute of Science. In 1976, he held up by sticks. Later on, as computer joined the faculty of the University of Southern Carolina, where he is modelling began to take off, scientists had now a distinguished professor of chemistry and biochemistry. to choose between classical and quantum physics to build their models. Neither was a Prof Warshel has always credited his curiosity for his interest in perfect solution: classical physics could be computational structural biology, explaining that his research was used to model very big molecules, but could akin to “seeing a watch, wondering what was going on inside, and not simulate chemical reactions; whereas finding out”. In particular, Prof Warshel is known for developing the field ARIEH WARSHEL quantum physics could simulate chemical of computational enzymology, which paved the way for quantitative reactions, but could only be applied small theoretical studies of enzymatic reactions. Nobel Prize in Chemistry molecules because it required enormous (2013) computing power. His contributions to chemistry have been considered outstanding by many organisations, including the US National Academy of Sciences, of In hindsight, combining the two methods which he is a member, and the Royal Society of Chemistry, of which he might seem like an obvious strategy. However, is a fellow. Additionally, the Southern California Section of the American Professor Arieh Warshel – together with his co- Chemical Society, neighbours of his long-time home at the University awardees Michael Levitt and of Southern California, awarded him the Tolman Medal in 2003. In 2013, – were the first to succeed, winning them the Prof Warshel was awarded the Israel Chemical Society Gold Medal. 2013 Nobel Prize in Chemistry. Despite the computational limitations of their time, where a single computer could take up an entire room, they were able to use computing technology to examine how and other biological substances look and work.

Prof Warshel had always been fascinated by science, desiring from a young age to understand how everything worked. He was born in Kibbutz Sde Nahum, in the Beit She’an Valley, now part of Israel. After attending the Technion – Israel Institute of Technology, where

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Look closer at the organic molecules that Called palladium-catalysed cross-coupling, the reaction is today a make life possible – proteins, carbohydrates, critical tool in any synthetic chemist’s toolbox and has been extensively nucleic acids – and you will find an underlying used by the pharmaceutical industry to discover and manufacture carbon skeleton. Strong and unusually stable, drugs such as vancomycin, an antibiotic used against drug-resistant the carbon-carbon (C-C) bond is the most bacteria. common chemical bond found in organic compounds. The ability to form long and After obtaining his Ph.D. at the University of Pennsylvania as a Fulbright- complex chains of C-C bonds underlies Smith-Mund Scholar in 1963, Prof Negishi joined Professor Herbert C. Nature’s dazzling diversity – and many of its Brown at Purdue University. In 1979, the year that Brown was awarded most useful compounds. his Nobel Prize, Prof Negishi was invited to join Purdue as faculty, where EI-ICHI NEGISHI he has been the H. C. Brown Distinguished Professor of Chemistry since But replicating C-C bonds in the lab has 1999. Prof Negishi now serves as the inaugural director of Purdue’s Nobel Prize in Chemistry proven to be challenging. Early attempts at Negishi-Brown Institute. (2010) forcing smaller carbon-containing molecules to form bonds with each other relied on Apart from the Nobel Prize in Chemistry, Prof Negishi has received the using highly reactive compounds to coax the 1987 J.S. Guggenheim Fellowship, the 1996 Chemical Society of usually stable carbon atoms into reactions. Award, the 1998 ACS Award in Organometallic Chemistry, the 2000 Sir Although they got the job done, these Edward Frankland Prize, the 2007 Yamada-Koga Prize, the 2010 ACS methods only worked under harsh conditions Award for Creative Work in Synthetic Organic Chemistry and the 2010 and caused the carbon atoms to form bonds Japanese Order of Culture. In 2011 and 2014, he was elected Fellow of in an unpredictable way, often resulting in the the American Academy of Arts and Sciences and Foreign Associate of generation of more unwanted by-products National Academy of Sciences respectively. than intended molecules.

Building on the work of fellow 2010 Nobel Laureate in Chemistry, Richard Heck, Professor Ei-ichi Negishi developed a more efficient way to link carbon-containing molecules using palladium as a catalyst. Palladium acts as an intermediary, binding the two carbon- containing molecules to itself and facilitating the formation of a new bond between them.

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Place some liquid in an open cup and Sir Anthony Leggett’s career in physics took an unconventional route, watch. Right before your eyes, you will see it involving two undergraduate degrees at Oxford University: firstly in what creeping up the edges of the cup, working is colloquially known as the Greats (classical languages, literature, and against , and then pooling at the base Greco-Roman history and philosophy) and secondly in physics. of the cup. You’ve just witnessed a superfluid in action. With his somewhat unorthodox academic background, he initially found it difficult to find a PhD supervisor willing to take him but was is a state in which matter behaves eventually accepted by Professor Dirk ter Haar, a theoretical like a fluid with zero friction, most dramatically at Oxford University. Reflecting his training in the Classics, Sir Anthony manifesting itself in counterintuitive movements Leggett is one of the few people who can claim to have written a PhD SIR ANTHONY that defy the forces of gravity and surface thesis on theoretical physics in Latin. LEGGETT tension. For example, while you would expect the water in your cup of tea to stop swirling In addition to the Nobel Prize, Sir Anthony Leggett has been awarded soon after you have stirred it, a superfluid the Medal and Prize (1991) and the highly coveted Wolf Prize (2003) would go on swirling for millions of years. in Physics for research on condensed forms of matter (2002). In 2004, he was knighted (KBE) by Queen Elizabeth II for his services to physics. The strange phenomenon of superfluidity was first demonstrated in experiments conducted on Helium-3 (3He) in 1972, earning Professors , and Robert Richardson the 1996 Nobel Prize in Physics. However, it was Sir Anthony Leggett who was able to provide a theoretical explanation for superfluidity, a contribution which earned him the Nobel Prize in Physics in 2003.

His decisive theory explained how the atoms of 3He form pairs and complex orders, properties required for 3He to behave like a superfluid. His theory not only helped experimentalists interpret their measurements but also provided a framework for future research. Furthermore, his theory has found widespread applications in diverse subjects from the physics of liquids to cosmology. 12 13 SPEAKERS SPEAKERS

The heaviest of the elementary particles, the experiments on the Super Synchrotron at CERN in 1982. W and Z had long been predicted by theory as the particles responsible for So significant and obviously important were his findings that the Nobel phenomena such as and Committee made the unprecedented move of awarding Prof Rubbia the combustion of the . However, until that and van der Meer the 1984 Nobel Prize in Physics, just over a year after momentous day in 1982, no one had ever their breakthrough discovery. experimentally proven that they existed—and no one knew if it was even possible. Forced to disrupt his studies and abandon his hometown of , during the Second World War, Prof Rubbia nonetheless managed to Einstein’s famous equation, E=mc2, predicted study physics at the Scuola Normale in after a brief false start in CARLO RUBBIA that it was possible to obtain mass – engineering at the . He went on to complete his Ph.D. including the – through the at before joining CERN, the European Organisation Nobel Prize in Physics transformation of energy. One of the main for Nuclear Research, in 1961, where he served as the Director General (1984) problems at the time was that there was no from 1989 to 1994. accelerator powerful enough to generate the energy required to produce W and Z. Since then, Prof Rubbia has turned his interests to the pressing global problem of energy, as the President of the Italian National Agency for To get around this problem, Professor Carlo New Technologies, Energy and the Environment (ENEA), the principal Rubbia proposed a radical new accelerator scientific adviser of the Spanish Research Centre for Energy (CIEMAT) design in 1976. Unlike standard accelerators and as advisor on energy to the and . where the majority of the energy is wasted on bringing the particles to high speeds rather In recognition of his contributions, Prof Rubbia was named an officer in than conversion into mass, he proposed the French Legion of Honour in 1989 and a member of the Polish Order smashing particles together in a head-on of Merit in 1993. In Italy, he was knighted in the Order of the Grand Cross collision. in 1985 and appointed Senator for life in 2013.

The second piece of the puzzle was supplied by Prof Rubbia’s co-Laureate , an accumulator that increased the current of antiproton several hundred thousand times. Together with a team of over 130 scientists, Prof Rubbia executed his plans in double quick time, running the first

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You might have been taught in high school Since the discovery of QCD theory, Prof Gross has been a central figure chemistry that atoms are made of a core of in . In particular, he has made important contributions to and neutrons surrounded by a cloud string theory, an ambitious attempt to reconcile existing theories about of atoms. But high school physics also says particle physics with gravity. that like charges repel each other, so what keeps the positively charged protons in the Born in the to an intellectual immigrant Jewish family from nucleus from flying apart? The answer is the Czechoslovakia-, Prof Gross moved to Israel in his teen years strong nuclear force, a force a hundred times and completed his undergraduate studies in physics and mathematics stronger than , a million at the Hebrew University. He received his Ph.D. in 1966 at UC Berkeley times stronger than the weak nuclear force and was previously Thomas Jones Professor of Mathematical Physics DAVID GROSS and a staggering 1038 times stronger than at . Formerly the Director of the Kavli Institute for gravity at the same range. Theoretical Physics at the University of California Santa Barbara, he is Nobel Prize in Physics currently the Frederick Gluck Professor of Theoretical Physics. (2004) Although the strong nuclear force was recognised as one of the four fundamental Prof Gross has been recognised with numerous awards including the J. forces of nature, many scientists believed that J. Sakurai Prize of the American Physical Society in 1986, the MacArthur it was impossible to find a theory that would Foundation Fellowship Prize in 1987, the in 1988, the Oskar allow the calculation of strong interactions. Klein Medal in 2000, and the Harvey Prize in 2000. He is a member of That changed in 1973 with a landmark scientific societies including the US National Academy of Science, the publication by Professor David Gross and his American Academy of Arts and Sciences, the American Philosophical Ph.D. student which showed Society, the Indian Academy of Science and the Chinese Academy of the counterintuitive result that the strong Science. interaction decreases with energy.

Called , or QCD, the theory made it possible to calculate strong interactions for the first time, and the results showed excellent agreement with experiments. For their contributions to the understanding of the fundamental forces of nature, Prof Gross, Wilczek and David Politzer were awarded the 2004 Nobel Prize in Physics.

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What if the entire Universe – in all its complexity The ’t Hooft-Veltman model was used, for example, to predict the and variety – could be described in a single mass of a called the top , which was only mathematical equation? It may sound experimentally observed much later in 1995. Glashow, Salam and impossible but we are actually almost there. Weinberg were awarded the 1979 Nobel Prize in Physics while Prof ’t The of particle physics Hooft and Veltman were recognised with the same honour 20 years explains all the known subatomic particles later in 1999. and three of the four fundamental interactions: strong nuclear force, electromagnetism and Prof ’t Hooft is also the recipient of the 1981 Wolf Prize, the 1986 Lorentz weak nuclear force. Only the last fundamental Medal and the 1995 Franklin Medal, among others. He was one of the force, gravity, remains unaccounted for. first to be awarded the Spinoza Prize, the highest scientific award in the GERARD ’t HOOFT Netherlands, and has been knighted commander in the Order of the The work of Professor Gerard ’t Hooft has helped Netherlands Lion and officer in the French Legion of Honour. Nobel Prize in Physics make the Standard Model even more elegant (1999) and powerful. Together with his Ph.D. supervisor Today, Prof ’t Hooft remains active in research on gravity and sub- at the time, Professor Martinus Veltman, Prof microscopic black holes. He is also an ambassador for the Mars One ’t Hooft developed the mathematics that project, an attempt to land the first humans on Mars and establish a allowed the unification of electromagnetism permanent colony there by 2027. and the weak nuclear force, showing that the two were actually manifestations of the same force.

Although a theory of unified electromagnetism had already been proposed by Professors , and in the 1960’s, attempts to make precise calculations were thwarted by meaningless results such as infinite probabilities. In 1971, Prof ’t Hooft published two landmark papers showing how the infinite probabilities could be tackled, a feat which allowed scientists to finally calculate the physical properties of subatomic particles with great precision.

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Although had been proposed as Museum School and enrolled at the University of to study elementary particles by the esteemed physics. Murray Gell-Mann and George Zweig in 1964, the scientific community at At the , Prof Friedman worked under Enrico the time found it hard to accept due to Fermi, a 1938 Nobel Prize winner in Physics known for building the first numerous fruitless experiments that had failed experimental nuclear reactor, and who left a deep influence on him. to definitively prove their existence. Prof Friedman’s research focus was on high energy physics, where he That all changed between 1968-69, when investigated particle structure and interactions of high energy electrons, Professor conducted neutrinos, and hadrons. He eventually received his Ph.D. in physics in JEROME FRIEDMAN experiments with Professors Henry W. Kendall 1956 and joined the physics faculty of the Massachusetts Institute of and Richard E. Taylor at the world-famous Technology in 1960. Nobel Prize in Physics Stanford Linear Accelerator Center. Through (1990) experiments that revealed the scattering of Prof Friedman is currently an Institute Professor at the Massachusetts electrons on protons and bound neutrons, Institute of Technology and is a member of the Board of Sponsors of The the three of them gave the first experimental Bulletin of the Atomic Scientists. In 2008, he received an honorary Ph.D. evidence to prove that quarks—the basic from the University of Belgrade. building blocks of matter—were indeed real. He is an honorary professor at the University of Belgrade’s Faculty of The discovery of quarks changed the scientific Physics and Faculty’s world famous institutes: Institute for Theoretical world’s view of the basic structure of matter and Experimental Physics, Institute of Physics Zemun and Vinca Nuclear and altered the future development of particle Institute. physics. For their pioneering investigations, Prof Friedman, Kendall and Taylor were awarded Prof Friedman is passionate about teaching and has commented that the Nobel Prize in Physics in 1990. he enjoys direct interaction with students. Outside of his vocation, he retains his childhood interests in art. He enjoys painting and studying As a child, Professor Friedman excelled in art Asian ceramic, and gains pleasure from various cultural activities such and entered a special arts programme in high as theatre, music and ballet. school. He later became interested in physics after reading Albert Einstein’s Relativity: The Special and General Theory. Against the strong advice of his art teacher, he turned down a scholarship to the Art Institute of Chicago

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We live at the scale of classical physics where 40,000km, equivalent to one trip around the earth. To gain information our logic dictates that any given particle can about the stuck in the trap without destroying them, highly only be at one place at a time. At the quantum activated atoms known as Rydberg atoms are passed through the trap scale, however, the laws of classical physics and detected on the other side. The changes that occur to the Rydberg break down, enabling a particle to be at two – atoms allow scientists to measure and even manipulate the quantum or even more – places at the same time. state of the photons in the trap.

Ever since Einstein first recognised that light For his role in advancing quantum physics, Prof Haroche was awarded is both a wave and a collection of particles the Nobel Prize in Physics in 2012 and the CNRS Gold Medal, the highest known as photons, the worlds of classical and scientific honour in France, in 2009. He is also the recipient of the 1997 SERGE HAROCHE quantum physics have collided. But without Charles Hard Townes Award, the 1992 Humboldt Prize and the 1988 the ability to precisely manipulate quantum Einstein Prize for Laser Science, among others. Nobel Prize in Physics particles, the only experiments that physicists (2012) could do were thought experiments, most Prof Haroche was born in , , where he first met famously exemplified by Schrödinger’s cat his wife, Claudine, as a fellow member of the tight-knit Russian Jewish paradox. community. After the tumultuous independence of Morocco in 1956, his family moved to France where he completed his high school education. Proposed in 1935 by Erwin Schrödinger, the thought experiment imagines a cat He subsequently entered the Ecole Normale Supérieure in Paris, where in a box, which could either be dead or he was supervised by Professor Claude Cohen-Tannoudji who went on alive, depending on whether a radioactive to win the Nobel Prize in Physics in 1997. It was in Paris too where he was particle had decayed or not, a quantum met Claudine again by chance after a 15 year interval. They married phenomenon. More than 60 years later, the following year and have two children. Professor Serge Haroche finally succeeded in turning Schrödinger’s thought experiment into reality, developing a trap that allowed the non-destructive observation of photons for the first time in 1996.

To achieve this, he first trapped several photons between two tiny superconducting mirrors, maintaining them for an unprecedented 130 milliseconds, during which time they travel over

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In the 19th century, ’s germ analysis concluded that there was no demand for such a vaccine, theory—the idea that germs cause disease— stalling the development for many years. Today, that prediction has helped humankind progress beyond proven to be misguided, with the market expected to grow from US$1.8 superstition, definitively linking unseen billion in 2001 to US$2.2 billion by 2018. More importantly, the highly bacteria and viruses to specific diseases such effective vaccines available have the potential to prevent 70 percent as tuberculosis and cholera. However, it took of cervical cancers, alleviating the suffering of many thousands of the next hundred years to convince the world women. that infectious agents could also be behind non-communicable diseases such as cancer. Prof zur Hausen’s interest in the role of viruses in cancers first began with his postdoctoral studies under the supervision of the renowned HARALD ZUR At the time Professor Harald zur Hausen first husband and wife team of Professors Werner and Gertrude Henle at HAUSEN began his research career, the scientific the Children’s Hospital of Philadelphia. Subsequently, he went on community was just starting to come around to appointments at the University of Würzburg and the University of Nobel Prize in Physiology to the idea. In the late 1960s, it was widely Erlangen-Nürnberg before settling at the University of Freiburg in 1977. or Medicine (2008) believed that the herpes simplex virus (HSV) There, he continued to work on HPV as well as other interesting projects was the cause of cervical cancer, the second such as the identification of a novel adeno-associated virus, AAV-5, most common cancer in women worldwide. from his own skin scrapings. However, Prof zur Hausen was unable to detect HSV in all the samples he tested, prompting In 2008, Prof zur Hausen was awarded the Nobel Prize in Physiology or him to search for an alternative explanation. Medicine for his seminal work on the role of HPV in cervical cancer. He was also awarded the Robert Koch Prize in 1975 for excellence in Turning his attention to genital warts, he was biomedical sciences, as well as the 2004 German Special Order of able to isolate and identify a new virus which Merit with Star. he believed to be the true cause of cervical cancer: human papilloma virus (HPV). After ten years of false starts and dead ends, Prof zur Hausen was finally able to identify HPV-16 and HPV-18, which together are found in 70 percent of all cervical cancers.

He then met a second obstacle when approaching companies to develop a cervical cancer vaccine based on his research. Market

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Once food is swallowed and sent to your Thanks to their pioneering work, peptic ulcers is no longer a chronic, stomach, it is attacked by harsh acid and frequently disabling condition, but a disease that can be cured by strong digestive enzymes. In that extreme a short regimen of antibiotics and acid secretion inhibitors. For their environment, where the pH can range from 1-3, contributions, Prof Warren and Dr Marshall were awarded the 2005 no bacteria are expected to survive. So when Nobel Prize in Physiology or Medicine. Professor Robin John Warren first proposed that bacteria living in the stomach were the cause Prof Warren was born in North Adelaide to a long line of doctors. He of peptic ulcers, his ideas were met with scorn. completed his secondary education at St Peter’s College where he found his father’s name carved into a desk and dated 1917. Prof Warren had first observed small, comma- Subsequently, he studied medicine at Adelaide University with the JOHN ROBIN shaped bacteria in biopsies of gastric tissue in help of a Commonwealth scholarship. While studying, he met his wife WARREN 1979. Over the next two years, he continued Winifred, with whom he now has five children. to find more examples of similar bacteria on Nobel Prize in Physiology gastric biopsies, always on the epithelium and Outside of his medical work, Prof Warren enjoys photography. His interest or Medicine (2005) closely linked to a specific variety of gastritis. in it was first cultivated as a child when he watched his father take family photographs with his old Voitlander camera. The first camera that Prof In 1981, Prof Warren met Dr , a Warren received was a Kodak box camera for his 10th birthday, thus registrar in the gastroenterology department sparking off a lifelong hobby of photography. Later on, he acquired of the Royal Perth Hospital. Together they a Leica M3 camera, which he used to photograph interesting clinical cultured the organisms and identified a new lesions as a medical student. species, now called Helicobacter pylori. They established a clear link between H. pylori and peptic ulcers, showing that once the bacterial infection was cleared, the ulcers too went away.

Prof Warren and Dr Marshall, who famously proved his hypothesis by drinking a H. pylori mixture and subsequently developing gastritis, found that the bacterium was a very “clever” infectious agent that could hide in the mucous lining protected from the acid, and could remain alive even for decades.

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According to the so-called Central Dogma he went on to complete a BSc in chemistry (1965) and a Ph.D. in organic of molecular biology: DNA makes RNA, and chemistry (1968) from the University of Sheffield, before making the leap RNA makes protein. Working on a common into the nascent field of molecular biology. cold-causing virus called adenovirus, Sir Richard Roberts made the surprising discovery From 1972 to 1992, Sir Richard Roberts conducted research at Cold that genes were in fact not continuous, but Spring Harbor Laboratory under the supervision of Professor James D. included stretches of DNA that did not code Watson, most famous for his path-breaking discovery of the double- for proteins which had to be “edited” out when helical structure of DNA which won him the 1962 Nobel Prize in Physiology the genes were expressed. or Medicine. At the time, the prevailing understanding of molecular genetics was based on bacterial DNA, where each gene was simply SIR RICHARD Subsequently, it was shown that 94 percent read as a continuous sequence. ROBERTS of all human genes are split genes and that defects in the joining process are the underlying In addition to his Nobel Prize winning work, Sir Richard Roberts has Nobel Prize in Physiology cause of diseases such as beta-thalassemia made significant scientific contributions through his isolation and or Medicine (1993) and chronic myeloid leukaemia. In 1993, Sir characterisation of more than 100 restriction enzymes, an essential tool Richard J. Roberts was awarded the Nobel in modern molecular biology. He is currently the Chief Scientific Officer Prize in Physiology or Medicine for his dogma- of New England Biolabs, a leading life science company specialising in shattering discovery of split genes, a finding restriction enzymes. that completely revised our understanding of how to read the human genome. Sir Richard Roberts was also an early advocate of the use of computer programmes in molecular biology and helped to develop the first Sir Richard Roberts had decided that he software to map and analyse DNA restriction enzyme fragments. He is wanted to be a chemist from an early age currently an advisor to the director of the NASA astrobiology programme and even had his own dedicated chemistry and has been the executive editor of the scientific journalNucleic Acids cabinet at home stocked with chemicals Research s i nce 1987. bought from a local pharmacist. Despite his interest in science, he found school boring and too narrowly focused on memorisation rather than problem solving, preferring instead to play chess or go caving.

Although adept at mathematics, he failed his first attempt at ‘A’ level physics. Nevertheless,

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Nothing lasts forever, and certainly not cells. To began to indicate the presence and function of . But try as he keep our bodies healthy, cells need to divide might, he could not explain why the cyclins would disappear around and replace themselves in a highly regulated the ten-minute mark before each . process called the . Following an internal clock, cells carry out activities such The summer of 1982 came to an end, also halting the research as Sir Tim as resting, growing and multiplying, precisely Hunt’s main residence of Cambridge did not have clams or urchins. It when the clock alarms go off. was only a few more summers later, in the Christmas of 1986, that Sir Tim Hunt’s team cloned the gene responsible for . The data helped It turns out that a family of proteins, known as his team describe the elegant mechanism by which cyclins controlled cyclins, are the ‘alarms’ that are central to the the cell-cycle: destruction of the cyclins released the cell into the next SIR TIM HUNT functioning of the cell cycle. In 2001, Sir Tim Hunt phase of the cell cycle, akin to a “go” signal. was awarded the Nobel Prize in Physiology or Nobel Prize in Physiology Medicine for his discovery of cyclins, which he Today, cyclins are featured in high school biology textbooks across or Medicine (2001) had named after his hobby of cycling. the world, and are considered the key actors in the cell cycle. For his important contributions to biology, Sir Tim Hunt was awarded the Nobel Sir Tim Hunt had made the decision to Prize in Physiology or Medicine in 2001. He was knighted by Queen become a biologist at a young age, realising Elizabeth II of the UK in 2006, the same year that he was awarded the that foreign languages were not his forte but . that the weekly science lesson was “an easy subject”. Sir Tim Hunt pursued his interest in biology at the , where he read both his undergraduate and doctoral degrees. There, he flourished particularly in experimental work, thriving under the tutelage of renowned scientists such as Professor .

In 1982, Sir Tim Hunt flew out to the Marine Biological Laboratory at Woods Hole, Massachusetts to teach summer courses, but also to study protein synthesis in and clam eggs after fertilisation. It was during this time that the first results of Sir Tim Hunt’s studies

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When a bottle of perfume is opened, the rigorous understanding of both Boltzmann and Landau, Professor Villani smell soon begins to fill the whole room. was awarded mathematics’ highest honour—the Fields Medal—in 2010. Unseen to the human eye, however, are the molecules of perfume randomly bumping Besides the Fields Medal, other honours include the Prize of the European against the air in the room. The Boltzmann Mathematical Society in 2008, the Fermat Prize in 2009 and the Henri equation, which can be used to calculate the Poincaré Prize of the International Association of Mathematical Physics probability that a molecule of gas would be in in 2009. Professor Villani is a Knight of the National Order of Merit (2009), a particular spot with a particular velocity at and a member of the Legion of Honor (2011) and the French Academy any particular moment, predicts that perfume of Sciences (2013). molecules would always move from the bottle CÉDRIC VILLANI to the rest of the room, increasing the entropy For many years, Professor Villani has been a global ambassador for the or randomness of the system to reach an French mathematical community. Among his many outreach projects, Fields Medal (2010) equilibrium. he has been involved in fostering mathematics in Africa with the Next Einstein Initiative and the World Bank. He is also leading the ambitious More than a century after Boltzmann first project of opening a museum of mathematics in Paris, and the voice of proposed his equation, scientists were still France’s campaign for the 2025 World Exhibition. no closer to understanding how fast entropy would increase. Together with his collaborators Nicknamed “the Lady Gaga of French mathematicians”, his own Giuseppe Toscani and Laurent Desvillettes, signature style is a three-piece suit, velvet cravat, pocket watch and Professor Cédric Villani made the surprising spider brooch from his collection of more than 30 customised brooches. finding that entropy in fact does not increase He has two children with his wife Claire, a biologist. at a fixed rate, even though it always increases.

Professor Villani subsequently went on to prove an exception to Boltzmann’s equation in an unusual state of matter known as plasma. Unlike in gas, plasma particles act in a collective manner, which Russian physicist Lev Davidovich Landau argued would allow them to reach equilibrium without increasing entropy. This was finally proven only six decades later by Professor Villani and his collaborator Clément Mouhot. For his work providing a

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In the language of mathematics, a donut Despite his eventual success, mathematics was actually a last resort for is the same as a coffee mug—at least in the Prof Smale after failing physics in his undergraduate studies. Although he field of topology. Topology is concerned had topped his high school and received a scholarship to study at the with what happens to shapes when they are University of Michigan, he was almost expelled from his undergraduate stretched or bent, without breaking or poking studies at the University of Michigan. holes into them. Therefore, a cube is the same as a sphere since it can be reshaped into a Nonetheless, he managed not only to complete his undergraduate one, but a sphere cannot be made into a studies but also finished his Ph.D. studies at Michigan in 1957. donut without creating a hole in the middle. Subsequently, he remained politically active, helping to organise anti- Similarly, a sufficiently pliable donut can war demonstrations in the 1960s and even receiving a subpoena from STEPHEN SMALE plausibly be reshaped into a coffee mug the House Un-American Activities Committee. without introducing or removing any holes, Fields Medal (1966) making donuts and coffee mugs topologically In addition to the Fields Medal, Prof Smale has been awarded many equivalent. other honours including the Von Neumann Award from the Society for Industrial and Applied Mathematics in 1989, the National Medal of Along this line of reasoning, mathematician Science in 1996 and the Wolf Prize in Mathematics in 2006. He is also Henri Poincaré famously proposed that all three known for his list of 18 problems in mathematics to be solved in the 21st dimensional objects are spheres, a conjecture century, which he wrote in 1998. that would fascinate mathematicians for the next hundred years. While Poincaré’s conjecture intuitively seemed possible for three dimensional objects, the generalised Poincaré conjecture—which states that the theorem is true for dimensions greater than four—was thought to be false.

Therefore, when Professor Stephen Smale first published his proof of the generalised Poincaré conjecture in 1961, it sent shockwaves through the mathematical world. In recognition of his contribution, Prof Smale was awarded the 1966 Fields Medal, a highly coveted honour only given out every four years to a mathematician under the age of 40. 34 35 SPEAKERS SPEAKERS

By 2050, it is estimated that there will be a 20 years to a pioneering technological innovator, for his development terawatt shortfall between energy needs and of dye-sensitised solar cells. In the following year, Prof Grätzel was production capacity. Furthermore, the burning conferred an honorary degree of Doctor of Engineering by Nanyang of fossil fuels to meet energy demands is an Technological University, Singapore, where he leads a team of increasingly unsustainable approach, given researchers at the Centre for Nanostructured Photosystems. the finite nature of these resources and their environmental impact. In contrast, the earth With more than 1,000 publications and 50 patents under his belt, Prof receives 81,000 terawatts of energy from the Grätzel has an h-index of 167, making him one of the top ten most cited sun, 5,000 times more than the total global chemists in the world. He has received numerous awards including two demand. However, harnessing that energy in McKinsey Venture awards in 1998 and 2002, and the Gerischer Prize in MICHAEL GRÄTZEL an efficient and cost effective way has proven 2005. More recently, he was awarded the Albert Einstein World Award to be challenging. of Science in 2012 and the Marcel Benoist Prize in 2013. Millennium Technology Prize (2010) As with many problems that mankind faces, Apart from his wide-ranging academic and commercial contributions, Nature seems to have already found an Prof Grätzel is also an accomplished pianist. At one point, he even elegant solution. Taking a leaf out of Nature’s considered becoming a professional musician instead of pursuing book, Professor Michael Grätzel has developed research. In opting for what he felt was a “safer bet”, Prof Grätzel has remarkable dye-sensitised solar cells inspired helped bring cheap, renewable energy one step closer to realisation. by photosynthesis in plants.

These dye-sensitised solar cells, which have since come to be known as Grätzel cells, use special dyes that mimic the ability of chlorophyll in plants to capture light and turn it into . Unlike conventional silicon- based solar cells, Grätzel cells are made of inexpensive materials, flexible and can work in low light conditions. They can also be integrated into liquids and gels, allowing them to be tinted and installed on window panels.

In 2010, Prof Grätzel received the Millennium Technology Prize, which is awarded every two

36 37 SPEAKERS SPEAKERS

Many of the technologies that we take for For driving the ‘big data’ revolution thanks to his application of spintronics granted today would not exist without the to data storage disk drives, Prof Parkin was awarded the 2014 Millennium phenomenal increase in storage capacity Technology Prize. Launched in 2004 and presented every two years by by computers. We can now stream music Technology Academy Finland, the prize is worth one million euros and is and movies from the Internet, all thanks to regarded as the Nobel Prize of the technology world. information stored in the cloud. The technology behind this cloud computing age is called A prolific inventor, Prof Parkin has authored over 400 papers and has spintronics, which was developed by Professor over 90 issued patents. For technology aficionados hoping to predict Stuart Parkin and which allows for a thousand the next frontier in nanotechnology, look no further: Prof Parkin is now fold increase in storage capacity. working on ‘cognitive devices’, which are memory or logic devices STUART PARKIN inspired by how we compute in our own brains. Prof Parkin was born in the southern English Millennium Technology town of Watford. After earning a Ph.D. degree Prof Parkin also wears many hats: he is head of the IBM Almaden Prize (2014) in physics at the in Research Centre in San Jose, and he is also a consulting professor at Cambridge, UK, he became a post-doctoral the department of applied physics. More recently, researcher at IBM, where he was made a he was appointed director of the Institute and Humbolt fellow in 1999, the highest technical honour Professor at the Martin Luther University of Halle-Wittenberg. His many granted by IBM. honours include memberships with the National Academy of Sciences and the National Academy of Engineering. In 2007, Prof Parkin was It was at IBM where Prof Parkin conducted named a distinguished visiting professor at the National University of much of his ground-breaking work on Singapore. spintronics, which exploits the magnetic spin rather than the flow of electrons to store computer bits. There, Prof Parkin also defied critics by showing that it was possible to use a simple technique called sputtering to increase the density of magnetic disk drives. Sputtering can be thought of as a way of coating a material that is similar to throwing apples into a tub of water and letting the splashes paint the carpet beneath it, using high energy atoms instead of apples.

38 39 SPEAKERS SPEAKERS

You might not realise it, but random numbers that he consider switching up his research focus, that Prof Yao moved are part of our everyday life. Activities from out of physics and into the world of . This would prove rolling dice during a game of Monopoly to to be a most fortuitous move, as Prof Yao has made significant and sending a confidential email at work all depend original contributions to data organisation, , and even on random number generation. While rolling quantum teleportation. dice is sufficient to introduce the randomness needed in a game, manual randomisation His shift to computer science saw him taking on a second doctoral quickly becomes unfeasible for more complex degree, this time at the University of Illinois at Urbana-Champaign in the processes like data encryption. This is where mid-1970s, under the tutelage of world-renowned computer scientist pseudorandom number generators come in. Prof David Chung-Laung Liu. In 2004, Prof Yao established the Institute ANDREW for Theoretical Computer Science (ITCS) at in , CHI-CHIH YAO But before we can start creating pseudorandom where he remains as its director. number generators, we need to figure out Turing Award (2000) what it is exactly that we want them to do. Apart from the Turing Award, which is considered the top prize in In 1982, Professor Andrew Yao formulated the computer science, he has also received the in 1996. In 2005, first convincing definition of a pseudorandom he won the Friendship Award, which is the highest award granted by number generator, which has since become the Chinese government to foreign experts who have contributed to known as Yao’s test. He also showed that the country’s economic and social progress. He is a member of the US certain one-way functions, which are easy National Academy of Sciences, a fellow of the American Academy to compute but very difficult to reverse, can of Arts and Sciences, and a foreign member of Chinese Academy of be used to construct pseudorandom number Sciences, among others. generators.

While he has made a great impact on computer science over the course of his career, it was not actually the first academic topic of choice for Prof Yao. Born in , , Prof Yao completed his higher education in physics at National University and .

It was only when Prof Yao’s wife Frances, herself an accomplished scholar, suggested to him

40 41 SPEAKERS SPEAKERS

For the most of us, a trip to the bakery rewards liveness, state machine replication and sequential consistency, are us with a freshly-baked loaf of bread. American among the most cited in the field of computer science. Dr Lamport computer scientist Dr Leslie B. Lamport, is also lauded for creating the document preparation tool LaTex, a however, came home with something even convenient typesetting tool which has become the de facto standard better: inspiration for the remarkably elegant for technical publishing. and intuitive Bakery algorithm, which is now taught to most computer science Born in 1941, Dr Lamport received a bachelor’s degree in mathematics undergraduates. from the Massachusetts Institute of Technology in 1960, a master’s degree in 1963 and a Ph.D. (1972) in mathematics from Brandeis University. The Bakery algorithm grapples with something Despite “a complete lack of education in computer science,” he delved LESLIE LAMPORT called the mutual exclusion problem: How do into computer science at Massachusetts Computer Associates, SRI you ensure that people approach cashiers International, Digital Equipment Corporation (later owned by Compaq) Turing Award (2013) one at a time, instead of bunching up at a and Microsoft Research, where he is now a principal researcher. single cashier? In computers, a straightforward solution is for one processor to wait when A love for solving real-world problem led Dr Lamport into industrial another is writing. Dr Lamport’s solution research. “If I just work by myself and come up with problems,” he said, arranges competing processes according to “I’d come up with some small number of things. But if I go out into the their arrival order, similar to receiving a queue world, where people are working on real computer systems, there are a ticket number at the bakery—when it is your million problems out there.” turn, you get sent to the next available cashier. In 2004, Dr Lamport received the IEEE Emanuel R. Piore Award. The By imposing clear, well-defined coherence on following year, his paper “Reaching Agreement in the Presence of seemingly chaotic behaviour, Dr Lamport’s Faults” received the Edsger W. Dijkstra Prize. In 2008, he received the work, allows software to function reliably even IEEE John von Neumann Medal. In 2013, Dr Lamport received the A. M. if it is running on a network of independent Turing Award, often referred to as the Nobel Prize of computing. He is a computers. It even allows the multiple cores fellow of the Association for Computing Machinery, and a member of of modern computer processors to be the US National Academy of Sciences and the US National Academy coordinated. In fact, his work has launched of Engineering. a whole new branch of computer science, known as distributed computing.

His papers, which introduced concepts such as causality and logical clocks, safety and

42 43 SPEAKERS SPEAKERS

Ask a wildlife photographer to identify a diploma in computer science from Imperial College, London, in 1973. He common bird species and you’ll probably get received a doctorate in computer science by the the answer in seconds. But what if he or she in 1974. Since 1982, he has been based at Harvard University, where has never seen that bird before? Chances are, he is now the T Jefferson Coolidge Professor of Computer Science and a veteran photographer would still come up Applied Mathematics in the Harvard School of Engineering and Applied with an educated guess, based on the bird’s Sciences. plumage, size and other features. Prof Valiant is a fellow of the Royal Society (London) and a member British computer scientist Professor Leslie of the National Academy of Sciences (USA). Other honours include Valiant theorised that machines can also the in 1986, the Knuth Prize in 1997, and the European LESLIE VALIANT “learn” by drawing upon experiences from Association for Theoretical Computer Science Award in 2008. He the past. In 1984, he developed the “probably received the Association for Computing Machinery’s 2010 A. M. Turing Turing Award (2010) approximately correct” (PAC) model of Award, the highest honour in computer science. machine learning, a learning algorithm that takes experiences from the past to derive a His newer research focuses on the many computational processes generalisation that is effective in correctly in neuroscience and biological evolution. He is also interested in the categorising examples not seen before. In computational building blocks that are necessary for cognition, or recent years, Prof Valiant has also adapted the artificial intelligence. Prof Valiant has authored two books: Circuits of the PAC model to provide a mathematical theory Mind and Probably Approximately Correct. In the latter, he challenges of the scope and limits of biological evolution, how we think about behaviour, cognition, biological evolution, and the framing Darwinian evolution in nature as a possibilities and limits of human and machine intelligence. form of PAC learning.

In artificial computation, Prof Valiant devised a scheme for the efficient routing of communications in very large parallel computing systems, and showed that the overheads involved even in a sparse network need not grow with the size of the system.

Born in 1949 in Budapest, Hungary, Prof Valiant received a bachelor’s degree in mathematics from the University of Cambridge in 1970 and a

44 45 SPEAKERS SPEAKERS

Can computers really solve everything? difficult to prove whether or not P equals NP. He showed that if any of This is the heart of the P versus NP problem, the well-known difficult problems could be solved efficiently, then all the identified by the Clay Mathematics Institute as problems could be efficiently solved. Since then, Prof Karp’s research one of the most difficult unsolved problems in has been applied to fields from parallel computing to computational mathematics. biology and more.

Polynomial or P-class problems are those that Reluctant to go out and “work for a living” after obtaining a degree can be solved within a reasonable amount of in mathematics from Harvard University, Prof Karp decided to do his computing time. In contrast, non-deterministic graduate studies. Drawn by the beauty and elegance of algorithms, polynomial or NP-class problems are those and discovering that he had a knack for the mathematics involved, he RICHARD KARP that computers find very difficult to come up stumbled into the nascent field of computing and never looked back. with an answer for, but can verify relatively Turing Award (1985) quickly. Putting together a very complex While on staff at the IBM Watson Research Centre, Prof Karp did jigsaw puzzle is an example of an NP problem foundational work on models of parallel computation, which is the for humans—it may take a long time to put the simultaneous use of multiple coordinated computers to solve a single jigsaw together, but once it is finished, it is easy problem. Turning his attention to the problems posed by the sudden to tell if it has been put together correctly. influx of biological information in the era of the Human Genome Project, Prof Karp developed algorithms that have enabled the study But are NP problems really just P problems in of population genetics, gene mapping and the analysis of biological disguise? If so, it would mean that for every pathways such as metabolic cycles and protein-protein interactions. difficult NP problem, there is a hidden shortcut that would allow computers to deal with Currently a University Professor at the University of California, Berkeley, a them at more manageable P problem scales. prestigious title that has been awarded only 38 times, Prof Karp has won However, if P is not equal to NP, then there will the Turing Award in 1985, the US National Medal of Science in 1996 and always be some problems that practically the Kyoto Prize in 2008, among others. remain out of the reach of computers. Up till today, mathematicians have not been able to come up with definitive proof on whether P is the same as NP, or not.

In 1972, Professor Richard Karp published a landmark paper which provided the first convincing explanation of why it was so

46 47 YOUNG SCIENTISTS INDEX

Australia Tang, Jing Aharonovich, Igor Wan, Biao Banfield, Julie Wang, Shaofei Bhaskaran, Madhu Wang, Dan Bradac, Carlo Xu, Tianyuan Brown, Hamish Galloway Yang, Ting Brown, Hannah Mary Yao, Xu-Ri Chahal, Arjun Singh Yasir, Kashif Ammar Chang, Wonkeun Yu, Liwei Hambleton, James Paul Yu, Wen-Kai Jamadar, Sharna Dyball Yuan, Xiang Lei, Weiwei Zhang, Liyuan Li, Shuai (Jack) Zhou, Dengji YOUNG Movassaghigilani, Sameneh Rahmani, Mohsen France Roberts, Matthew John Aloulou, Hamdi SCIENTISTS Schwarz, Kyra Noelle Antier Murgey, Marie Slangen, Aimée Berthe Agnès Brunner, Daniel Vallence, Ann Maree Genot, Anthony INDEX Millard, Pierre Brunei Moullec, Marie-Lise Keasberry, Natasha Nothias-Scaglia, Louis-Félix Leong, Elvynna Reveillac, Anthony Sallantin, Renaud China Silverston, Thomas Ahmed, Shifa Tofik Tiberghien, Thibaut An, Sai Tredan, Gilles Dong, Ruijiao Fu, Minfan Huang, Qingzi Bernard, Jürgen Edgar Jiang, Long Bröcker, Felix Muzammal, Hussain Cupid, Damian Marlon Talib, Hussain Geder, Jan

49 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

Gschwind, Fabienne Israel Republic of Korea Lee, Shen-Han Heublein, Marion Aviram, Naama Hwang, Doyk Li, Si Link, Julia Monika Boyarski, Amit Kang, Jooyoun Li, Yuchen Ma, Jingting Eyal, Zohar Kim, Hyeongmin Lim, Edwin Chai Mohr, Claudia Kumar, Vijay Bhooshan Kim, Seong-Hoon Liu, Shiyu Ranjan, Priyadarshi Kim, Dong-Su Liu, Yuchun Hong Kong Ronen, Yuval Lee, Eun-Seo Mateo, David Chow, Yin Lam Shaham, Yonatan Lee, Sejin Mikos, Val Holst, Christopher Claus Shefet-Carasso, Leeron Sol Park, Sei Jin Mok, Sachel Shu-Li Lam, Hiu Yue Monatrice Tsybulsky, Diana Park, Ji-a Motovilova, Elizaveta Lee, Yiu Yiu Zviran, Asaf Song, Jung-Ah Narasimhalu, Kaavya Leung, Hiu Ning Ng, Yi Zhen Li, Haobo Italy Singapore Nguyen, Thanh Son Li, Liping Niculaes, Dina Arikan, Ugur Novitsky, Denis Luo, Xiangyu Arora, Mohit Ong, Sze Wei Daniel Shen, Shanpu Japan Bai, Zuo Ong, Corinne Sun, Huayu Liu, Zhi Bhattacharya, Prasanta Pan, Zhengxiang Tang, Clara Sze-man Sim, Woohyang Chan, Soon Kiat Jeremy Parida, Kaushik Tse, Ying Lung Sun, Xiaomin Chen, Manman Peh, Boon Pin Wei, Xiaoming Wang, Hai Chen, You-Lin Peh, Hong Yong Xu, Wenying Chen, Zhuo Plisko, Tatiana Yang, Wu Chen, Zhili Poh, John Ye, Yifan Wang, Chunming Chowdhury, Prannoy Priyashri, Sridhar Zhou, Ao Gan, Weiliang Pun, Boon Li Pamela Zhu, Yixuan Malaysia Goh, Shireen Purushothuman, Sivaraman Chan, Kok Meng Goh, Jonathan Pusharath Gopi, Smitha Kavallur India Masarudin, Mas Jafri Googhari, Meysam Sadeghi Quah, Hong Sheng Bardhan, Debjyoti Othman, Siti Sarah Heng, Jian Yong Lionel Rangarajan, Parakalan Ghosh, Sanat Hong, Hui Qi Ren, Zhihua Sanyal, Swagato Pakistan Huang, Ying Rozali, Muhammed Esdy Nazim Bin Sharma, Divyum Chattha, Aftab Ahmad Ivanets, Andrei Setyawati, Magdiel Inggrid Yadav, Anupama Salman, Tabinda Koh, Cheryl Mei-Yi Shabunya-Klyachkovskaya, Elena Lai, Chooi Mun Deborah Siah, Keng Boon

50 51 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

Sim, Yirong Standfest, Matthias Goyal, Aanchal Singh Kochhar, Pavneet Tapias, Estefania Adlam, Emily Holzer, Stephan Soon, Jia Mei Jamie Wielopolski, Mateusz Banks, Joseph Khovalyg, Dolaana Sun, Zhenglong Chen, Mingsheng Lee Chung, Bomy Tan, Hui Teng Taiwan Davis, Frances Lim, Chong-U Tan, Yaw Sing Chang, Gao-Fong Dominguez Bucio, Thalia Lindawati Tan, Bing Wen Chen, Wei-Chao Engelke, Simon Liu, YuHao Tan, Say Hwa Cho, Hsin-hua Foets, Thomas Ni, Peng Tan, Maxine Hui Yan Huang, Teng-Kuei Gaitskell, Kezia Odour, Erick Tan, Wun Kiat Justin Ko, Chia-Ying Jessie Hajmohammadi Hosseinabadi, Hajar Razikin, Khasfariyati Binte Tay Kah Ping, Andy Lin, Hsiu Chuan Hatch, Sabina Vo, Hoang Tam Teo, Teck Hui Tan, Jake Acedera Hung, Tzu-Yi Wang, Chen Thilarajah, Shamala Wang, Zi-Fu Lavery, Domaniç Wang, Lanjun Trukhanov, Alex Wu, Lien-szu Lorenzi, Marco Yang, Haodan Venkataraman, Aditya McClelland, Harry-Luke Oliver Wong, Him Cheng Thailand Murray, Robert Vietnam Wu, Fang Chinda, Kroekkiat Peruzzotti-Jametti, Luca Ha, Nhan Yang, Bo Khongkow, Mattaka Pilgrim, Ben Nguyen, Chuong Yap, Kim Thow Noppakaew, Passawan Powell, Samuel Tran, Hanh Yong, Ming Hui Nunkaew, Jirakan Schumacher, Linus Julian Yong, Ee Juen Hannah Suwansang Janjaroen, Dao Studic, Milena Zhao, Liya Tan Wei Yee, Adrian Zheng, Chaodong The Netherlands Thill, Patrick Biljecki, Filip Thomsen, Soeren Sloth Sweden Chi, Heng Van Wilgenburg, Bonnie Antypas, Charalampos Frommhagen, Matthias Asghar, Muhammad Mokhles, Sahar United States of America Gerling, Marco Mokhles, Palwasha Akhtar, Aadeel Gong, Tong Putri, Rindia Maharani Cai, Danqing (Jessie) Tesi, Bianca van de Laar, Ties Castro-Gonzalez, Carlos van den Brink, Floris Teunis Gerardus Chao, Ran van der Helm, Marieke Willemijn Conway, Claire Javadian, Alireza Vijselaar, Wouter Duarte Guevara, Carlos

52 53 YOUNG SCIENTISTS DIRECTORY

IGOR, AHARONOVICH

Male Australian Research Council Australia [email protected]

JULIE BANFIELD

YOUNG Female Australian National University Australia SCIENTISTS [email protected] Research Interests: DIRECTORY Astrophysics - Galaxies formation and evolution. Citizen science - Project scientist for the Radio Galaxy Zoo citizen science project.

MADHU BHASKARAN

Female Australian Research Council Australia [email protected]

Research Interests: Flexible micro- and nano-structures and novel functional materials.

55 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

CARLO BRADAC ARJUN SINGH CHAHAL

Male Male Australian Research Council University of Melbourne Australia Australia [email protected] [email protected]

Research Interests: Colour centres in nanodiamonds (NDs).

HAMISH GALLOWAY BROWN WONKEUN CHANG

PhD Male Male Australian National University University of Melbourne Australia Australia [email protected] [email protected] Research Interests: Research Interests: Photonics and high-power lasers. Nonlinear dynamics in laser systems, Ultrafast Theoretical Condensed Matter Physics. Theories of image formation in electron nonlinear optical phenomena. microscopes.

HANNAH MARY BROWN JAMES PAUL HAMBLETON

Female Male Australian Research Council Australian Research Council Australia Australia [email protected] [email protected]

Research Interests: Research Interests: Pre-implantation embryo and the epigenetic mechanism. Soil ploughing and cutting, fundamental earthmoving processes that lie at the heart of applications in civil construction, mining and tribology.

56 57 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

SHARNA DYBALL JAMADAR SAMENEH MOVASSAGHIGILANI

Female PhD Student Australian Research Council, Australia Female [email protected] Australian National University Australia Research Interests: [email protected] To fully understand the changes in the brain that contribute to age-related decline in cognition, to develop cost-effective mechanisms for maintaining Research Interests: cognitive health into old age. Wireless Body Area Networks (WBANs).

WEIWEI LEI MOHSEN RAHMANI

Male Male Australian Research Council Australian National University Australia Australia [email protected] [email protected]

Research Interests: Research Interests: Designing novel two- and three-dimensional porous nanomaterials, developing Nanophotonics, Linear and Nonlinear optical properties of photonic materials. new nanomaterials for water cleaning, environment protection and energy conversion and storage devices.Boron nitride nanomaterials.

SHUAI LI (JACK) MATTHEW JOHN ROBERTS

PhD Student Male Male Australian Research Council Australian National University Australia Australia [email protected] [email protected]

Research Interests: Semiconductor Materials. Device and Materials (metal-insulator transition (MIT) in strongly correlated oxides and exploring potential in neuromorphic computing). New Computing paradigms

58 59 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

KYRA NOELLE SCHWARZ NATASHA KEASBERRY

Female Female University of Melbourne Universiti Brunei Darussalam Australia Brunei [email protected] [email protected]

Research Interests: Research Interests: Chemistry, Materials Science, Renewable energy. Inorganic chemistry, Bioimaging, Nanoparticles.

AIMÉE BERTHE AGNÈS SLANGEN ELVYNNA LEONG

Female Female Australian Research Council Universiti Brunei Darussalam Australia Brunei [email protected] [email protected]

Research Interests: Research Interests: Climate models and sea level changes. Statistics

ANN MAREE VALLENCE SHIFA TOFIK AHMED

Female Male Australian Research Council Chinese Academy of Sciences Australia China [email protected]. [email protected]

Research Interests: Facile design of low dimensional transition metal dichachogenides for water splitting.

60 61 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

SAI AN QINGZI HUANG

Female Female Fudan University Xi’an Jiaotong University China China 111110 3 0 0 0 2@f u d a n.ed u.cn [email protected]

Research Interests: Research Interests: To develop novel RNA interference treatments for cerebral aging-associated Circular economy and Environmental management. diseases.

RUIJIAO DONG LONG JIANG

Male Male Shanghai Jiao Tong University Shanghai Jiao Tong University China China [email protected] [email protected]

Research Interests: Research Interests: Supramolecular chemistry, Biomedical materials and Nanotechnology. Sorption refrigeration technology.

MINFAN FU HUSSAIN MUZAMMAL

Male Male Shanghai Jiao Tong University Chinese Academy of Sciences China China [email protected] [email protected]

Research Interests: Power electronics, radio wave circuits, control, optimization and their applications in wireless power transfer (WPT).

62 63 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

HUSSAIN TALIB SHAOFEI WANG

Male Female Chinese Academy of Sciences Fudan University China China [email protected] [email protected] Research Interests: Therapies for Diabetes Mellitus and its complications, Regulation of Autophagy to Enhance the Efficacy of Cancer Therapy, Research and Development of VLPs- based Therapeutic Hepatitis B Vaccine, Modulation of autophagy to enhance the safety of nanomaterials that are intended for biomedical applications.

JING TANG DAN WANG

Female Female Fudan University Xi’an Jiaotong University China China [email protected] [email protected]

Research Interests: Research Interests: Neuron-nanowire interfaces for artificial retina. Public Administration.

BIAO WAN TIANYUAN XU

Male Male Chinese Academy of Sciences Shanghai Jiao Tong University China China [email protected] [email protected]

Research Interests: Research Interests: Theoretical physics and mathematics including quantum, gravity theory, Roles and mechanisms of microRNAs (miRNAs) in bladder cancer. topology and non-equilibrium statistical physics.

64 65 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

TING YANG LIWEI YU

Female PhD Candidate Xi’an Jiaotong University Male China Nankai University [email protected] China [email protected] Research Interests: Marriage Welfare and Family Development Research Interests: The topological quantum computation based on the Yang-Baxter equation and the corresponding models.

XU-RI YAO WEN-KAI YU

PhD PhD Male Male Nankai University Nankai University China China [email protected] [email protected]

Research Interests: Research Interests: Super-resolution, Ghost imaging and Single-pixel camera. Optical theory and experiment such as imaging under ultra- weak light illumination conditions.

KASHIF AMMAR YASIR XIANG YUAN

Male Male Chinese Academy of Sciences Fudan University China China [email protected] [email protected]

Research Interests: Topological Dirac-semi-metal. Two Dimensional Optoelectronics Devices.

66 67 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

LIYUAN ZHANG MARIE ANTIER MURGEY

Male Female Xi’an Jiaotong University Thales China France [email protected] [email protected]

Research Interests: Research Interests: Particulate Pollution. High power lasers, quantum cascade lasers, fiber lasers, coherent beam combining.

DENGJI ZHOU DANIEL BRUNNER

Male Male Shanghai Jiao Tong University CNRS China France [email protected] [email protected]

Research Interests: Research Interests: To increase the efficiency and cut the operating costs of energy conversion Physics, Quantum physics, Laser spectroscopy of coherent quantum states in system. single quantum dots.

HAMDI ALOULOU ANTHONY GENOT

Male Male CNRS CNRS France France [email protected] [email protected]

Research Interests: Research Interests: Informatics, ambient assisted living, context awareness, semantic reasoning, DNA nanotechnology, Molecular Programming and unconventional smart space. computing.

68 69 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

PIERRE MILLARD ANTHONY REVEILLAC

Male Male National Institute of Applied Sciences in Lyon (INSA) National Institute of Applied Sciences in Lyon (INSA) France France [email protected] [email protected]

Research Interests: Research Interests: Systems and synthetic biology, metabolic network, metabolic fluxes, predictive Mathematical finance, stochastic analysis, Malliavin calculus, Limit theorems, modelling. Bayesian inference.

MARIE-LISE MOULLEC RENAUD SALLANTIN

Female Male Thales Thales France France [email protected] [email protected]

Research Interests: Research Interests: Complex systems design, Semi automatic generation of complex systems Satellite communication systems, network performances. architectures using combination of bayesian approaches and constraints satisfaction methods.

LOUIS-FÉLIX NOTHIAS-SCAGLIA THOMAS SILVERSTON

Male Male CNRS CNRS France France [email protected] [email protected]

Research Interests: Research Interests: Natural Products Chemistry, Mass spectrometry and Nuclear Magnetic Content distribution, Network and Performance Analysis, Peer-to-peer dispatch Resonance Structural ElucidationLC-MSn-based Metabolomic / of live video streams. BioinformaticMass spectrometry imaging.

70 71 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

THIBAUT TIBERGHIEN FELIX BRÖCKER

Male Male CNRS Max-Planck Institutes France Germany [email protected] [email protected]

Research Interests: Research Interests: Computer science, Infrastructure and algorithmic solutions, wearable sensing Vaccine discovery, Immunology, Carbohydrate biochemistry. and ambient sensing, internet of things, ambient assisted living, smart cities.

GILLES TREDAN DAMIAN MARLON CUPID

Male Male National Institute of Applied Sciences in Lyon (INSA) Karlsruhe Institute for Technology France Germany [email protected] [email protected]

Research Interests: Research Interests: Large scale distributed systems, Complex networks processing, Mobile data Combination of computer supported modelling and simulation with mining, Interdomain routing security, Internet measurement process modelling. experimental phase diagram, thermochemical, and thermodynamic investigations of multi-component material systems.

JÜRGEN EDGAR BERNARD JAN GEDER

Male Male Fraunhofer Technical University of Munich Germany Germany [email protected] [email protected]

Research Interests: Visual Analysis of Multivariate Data and Time Series Data.

72 73 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

FABIENNE GSCHWIND JINGTING MA

Female PhD Student Karlsruhe Institute for Technology Female Germany Fraunhofer [email protected] Germany [email protected] Research Interests: Room temperature fluoride ion batteries, Coordination Chemistry (mixed metal Research Interests: complexes), Cluster Compounds and Crystallography, Anion Technology. Biomedical image segmentation and registration.

MARION HEUBLEIN CLAUDIA MOHR Female Karlsruhe Institute for Technology Female Germany Karlsruhe Institute for Technology [email protected] Germany Research Interests: [email protected] Water vapour modelling, tomographic reconstruction, spatial and temporal variability, weather forecast, numerical weather models, and climate change. Research Interests: Atmosphere modelling and displacement detection using Global Navigation Air quality and climate impacts of atmospheric particulate matter. Satellite Systems (GNSS) and Interferometric Synthetic Aperture Radar (InSAR). Compressive Sensing: Robust reconstruction of sparse signals, e.g., for environmental modelling.

JULIA MONIKA LINK YIN LAM CHOW

PhD Student Male Female Croucher Foundation Karlsruhe Institute for Technology Hong Kong Germany [email protected] [email protected] Research Interests: Research Interests: To devise efficient algorithms for risk-aware planning and control of autonomous Physics and the study of electronical transport properties of graphene in the systems in uncertain environments, where threats, dynamic events, and partial collisionless limit. knowledge of world models are dominant features.

74 75 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

CHRISTOPHER CLAUS HOLST HIU NING LEUNG

Male Female City University of Hong Kong Chinese University of Hong Kong Hong Kong Hong Kong [email protected] [email protected]

Research Interests: Research Interests: Urban impact upon Precipitation and Convective Storm Cells. Effectiveness of Protection on Fish Assemblages in Non-reefal Communities.

MONATRICE LAM HIU YUE HAOBO LI

Female Male Croucher Foundation University of Hong Kong Hong Kong Hong Kong [email protected] [email protected]

Research Interests: Normal and oncogenic cellular signal transduction using principles drawn from physical chemistry, molecular biology and material science.

YIU YIU LEE LIPING LI

Male Female University of Hong Kong Hong Kong University of Science & Technology Hong Kong Hong Kong [email protected] [email protected]

Research Interests: Research Interests: Methionine oxidised apoA-I (MetO-ApoA-I) fibril formation in the presence of The transformation of emerging micro pollutants and their biological risk to phosphocholine derivatives. Mass spectrometry. human beings and environment.

76 77 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

XIANGYU LUO CLARA SZE-MAN TANG

Male PhD Student Chinese University of Hong Kong Female Hong Kong University of Hong Kong [email protected] Hong Kong [email protected]

SHANPU SHEN YING LUNG TSE

Male Male Hong Kong University of Science & Technology Croucher Foundation Hong Kong Hong Kong [email protected] [email protected]

Research Interests: Research Interests: Antenna Design for RF Energy Harvesting, Communication Improving the techniques for studying proton solvation and transport.

HUAYU, SUN XIAOMING WEI

Male Male City University of Hong Kong University of Hong Kong Hong Kong Hong Kong [email protected] [email protected]

Research Interests: Advanced Electronice Packaging Technology, Semiconductor Reliability, Failure Analysis & Materials in Electronics

78 79 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

WENYING XU AO ZHOU

Female Male City University of Hong Kong City University of Hong Kong Hong Kong Hong Kong [email protected] [email protected]

Research Interests: Research Interests: Neural Networks, Internet congestion networks, Distributed Sensor Networks Innovative Design for Sustainable Building & Structural Retrofitting through Fiber Reinforced Ploymer.

WU YANG YIXUAN ZHU

Male PhD Student Chinese University of Hong Kong Female Hong Kong University of Hong Kong [email protected] Hong Kong [email protected] Research Interests: Transition Metal Complexes Promoted C-C Single Bond Activation. Research Interests: Urban computing and big data analytics.

YIFAN YE DEBJYOTI BARDHAN

Male Male City University of Hong Kong Tata Institute of Fundamental Research Hong Kong India [email protected] [email protected]

Research Interests: Research Interests: Design of High Entropy alloys. High energy physics, Physics beyond the Standard Model at particle colliders like LHC.

80 81 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

SANAT GHOSH ANUPAMA YADAV

Male Female Tata Institute of Fundamental Research Tata Institute of Fundamental Research India India [email protected] [email protected]

Research Interests: Research Interests: Hydrogen bonding in chemistry and biology, Vibrational spectroscopy. Microbiology, Quantitative genetics, Plasticity variation in yeast.

SWAGATO SANYAL NAAMA AVIRAM

Male Female Tata Institute of Fundamental Research Weizmann Institute of Science India Israel [email protected] [email protected]

Research Interests: Research Interests: Computer Science, Computational Complexity, Boolean function analysis, Targeting and translocation to the endoplasmic reticulum: uncovering Algorithms. elements of a novel SRP-independent pathway.

DIVYUM SHARMA AMIT BOYARSKI

Female PhD student Tata Institute of Fundamental Research Male India Tel Aviv University [email protected] Israel [email protected] Research Interests: Number theory in mathematics, Diophantine equations and approximations. Research Interests: Inverse problems, Image processing, Computer Vision, Medical imaging, Machine learn-ing, Optimization.

82 83 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

ZOHAR EYAL YUVAL RONEN

Female Male Weizmann Institute of Science Weizmann Institute of Science Israel Israel [email protected] [email protected]

Research Interests: Research Interests: Structural study of pathogenic bacterial ribosome, utilizing various research Nano-wires heterostructures and high efficiency splitting strategies. Crystals characterization and data collection in 3rd generation cooper pairs resulting with entangled electrons. synchrotrons (ESRF, APS, SLS).

VIJAY BHOOSHAN KUMAR YONATAN SHAHAM

Male PhD student Bar-Ilan University Male Israel Tel Aviv University [email protected] Israel [email protected] Research Interests: Bar-Ilan Institute of Nanotechnology and Advanced Materials. Research Interests: Modeling of Fires Following Earthquakes for Assessment Firefighting Strategies.

PRIYADARSHI RANJAN LEERON SOL SHEFET-CARASSO

Male PhD student Weizmann Institute of Science Female Israel Tel Aviv University [email protected] Israel [email protected] Research Interests: Electron transfer studies of decorated inorganic nanotubes of tungsten Research Interests: disulphide. Multi-functional, antibody-integrated biomaterials for tissue engineering. Molecular biology, antibodies engineering and tissue engineering.

84 85 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

DIANA TSYBULSKY ZHI LIU

Female Male Tel Aviv University Israel Japan [email protected] [email protected]

Research Interests: Collaborative Web based Labs for Science Education

ASAF ZVIRAN WOOHYANG SIM

PhD Female Male Waseda University Weizmann Institute of Science Japan Israel [email protected] [email protected]

Research Interests: Regulatory mechanisms in stem cells and development.

DINA NICULAES XIAOMIN SUN

Female Female Italian Institute Of Technology Waseda University Italy Japan [email protected] [email protected]

Research Interests: To develop colloidal magnetic nanoparticles as nano-platforms for a combined cancer treatment, based on magnetically induced hyperthermia and temperature triggered drug release.

86 87 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

HAI, WANG MAS JAFRI MASARUDIN

Male Male Fujitsu Ministry of Science Technology and Innovation Japan Malaysia [email protected] [email protected]

Research Interests: Research Interests: Operations Research methodologies to analyze the complex systems described Development of novel nanoparticles as candidate vectors for anti-cancer by big data, dealing with complex structures, inherent stochasticity, and large therapies. scales.

CHUNMING WANG SITI SARAH OTHMAN

Male Female University of Macau Ministry of Science Technology and Innovation Macau Malaysia [email protected] [email protected]

Research Interests: Research Interests: The study of biomedical tools for drug delivery, regenerative medicine and Developing live-attenuated vaccines against veterinary diseases. cancer immunotherapy.

KOK MENG CHAN AFTAB AHMAD CHATTHA

Male Male Ministry of Science Technology and Innovation National Academy of Young Scientists (NAYS) Malaysia Pakistan [email protected] [email protected]

Research Interests: Toxicology

88 89 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

TABINDA SALMAN HYEONGMIN KIM

Female Male National Academy of Young Scientists (NAYS) National Research Foundation of Korea Pakistan Republic of Korea [email protected] [email protected]

Research Interests: Pharmacy

DOYK HWANG SEONG-HOON KIM

Male Male National Research Foundation of Korea National Research Foundation of Korea Republic of Korea Republic of Korea [email protected] [email protected]

Research Interests: Research Interests: Physical ChemistryUltrafast SpectroscopyNonlinear Spectroscopy Biology, Drug development, DNA damage repair

JOOYOUN KANG DONG-SU KIM

Female Male National Research Foundation of Korea National Research Foundation of Korea Republic of Korea Republic of Korea [email protected] [email protected]

Research Interests: Research Interests: Chemistry Medical Physics, Radiological Science

90 91 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

EUN-SEO LEE JI-A PARK

Female Female National Research Foundation of Korea National Research Foundation of Korea Republic of Korea Republic of Korea [email protected] [email protected]

Research Interests: Research Interests: Chemical and Biological Engineering, Stem cell and tissue engineering, Food and Nutrition, Dentistry Genome editing

SEJIN LEE JUNG-AH SONG

Male Female National Research Foundation of Korea National Research Foundation of Korea Republic of Korea Republic of Korea [email protected] [email protected]

Research Interests: Research Interests: Biochemistry Chemistry & Nanoscience

SEI JIN PARK UGUR ARIKAN

Male Male National Research Foundation of Korea SUTD Republic of Korea Singapore [email protected] [email protected]

Research Interests: Research Interests: Mechanical Engineering Transportation and Logistics Optimization Theory Supply Chain Management Graph Theory and Networks Energy Green O.R.Scheduling / Rescheduling

92 93 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

MOHIT ARORA SOON KIAT JEREMY CHAN

Male PhD Student SUTD Male Singapore NTU [email protected] Singapore [email protected] Research Interests: Infectious Diseases, Mechanobiology, Microfluidics, Waste Management for Research Interests: Sustainable Cities Formal methods, web security, software engineering

ZUO BAI YOU-LIN CHEN

Male Male Delta Electronics Singapore Delta Electronics Singapore Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: Machine learning, deep learning, pattern recognition, extreme learning Wireless Communications and Mobile Computing machine

PRASANTA BHATTACHARYA ZHUO CHEN

Male Male NUS Keppel Singapore Singapore [email protected] [email protected]

Research Interests: Computational Social Science, Computational Social Psychology, Machine Learning

94 95 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

ZHILI CHEN SHIREEN GOH

Female Female Contact Singapore A*STAR Singapore Singapore [email protected] [email protected]

Research Interests: Multidisciplinary research developing new microfluidic devices and biosensors for high throughput and miniaturized biological experiments.

PRANNOY CHOWDHURY JONATHAN, GOH

Male Male SembCorp A*STAR Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: Environmental technologies. Water and Waste water Treatment. Returnable Cyber Security, Digital Forensics, Multimedia security, Computer vision, energy. Evolutionary computation, Deep learning on conventional cyber security problems.

WEILIANG GAN MEYSAM SADEGHI GOOGHARI

PhD Student Male Male SUTD NTU Singapore Singapore [email protected] [email protected] Research Interests: Research Interests: Application of mathematical theories, statistics and optimization in wireless Spintronic Devices, Magnetic Nanoparticles. communication networks with special interest in the following theories and applications: Random Matrix Theory. Convex Optimization. Massive MIMO Communication.

96 97 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

JIAN YONG LIONEL HENG ANDREI IVANETS

Male Male DSO / DSTA Belarus Foundation for Fundamental Research Singapore Singapore [email protected] [email protected]

Research Interests: Specializes in the application of computer vision and machine learning to field robotics. Such applications include automatic multi-sensor calibration, visual mapping, visual localization, path planning, and path optimization.

HUI QI HONG CHERYL MEI-YI KOH

Female Female NUS A*STAR Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: Structural remodeling by DEAH box helicase 9 (DHX9) regulates Adenosine-to- Cancer Genetics and Therapeutics. Laboratory of Chromatin, Epigenetics and Inosine (A-to-I) editing. Differentiation.

YING, HUANG CHOOI MUN DEBORAH LAI

Male Female A*STAR SingHealth Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: CMOS compatible multi-layer Si3N4-on-SOI platform for silicon photonics. Cancer metabolism Integrated entangled photon source for Quantum communication, Polarization- diversity circuit for silicon photonics devices, Investigation of Raman effect in silicon/chalcogenide waveguide, Integrated Polarization-entangled photon pair generation 98 99 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

SHEN-HAN LEE EDWIN CHAI, LIM

Male Male SingHealth Contact Singapore Singapore Singapore [email protected] [email protected] Metabolomics (Tryptophan)

Research Interests: Neurochemistry, Neuroinflammation and Neurodegeneration

SI LI SHIYU LIU

Female Male NUS A*STAR Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: Emerging contaminants removal Surface Technology

YUCHEN LI YUCHUN LIU

Male Female NUS SingHealth Singapore Singapore [email protected] [email protected]

Research Interests: Social Network Extreme Search

100 101 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

ELIZAVETA MOTOVILOVA DAVID MATEO

Female Male SUTD SUTD Singapore Singapore [email protected] [email protected] Research Interests: Research Interests: Bio-medical devices, their development and improvement. Magnetic Emergent collective behaviours in nature Information transmission and diffusion resonance imaging (MRI), high field systems, MR engineering, Electromagnetics, in networks. Artificial swarming in land and marine robots for collective sensing. modelling & simulation. Efficient control of complex systems.

VAL MIKOS KAAVYA NARASIMHALU

Male Female NUS SingHealth Singapore Singapore [email protected] [email protected]

Research Interests: Energy Efficient Architecture & IC Design for Biomedical and Tele-health Applications

SACHEL SHU-LI MOK YI ZHEN, NG

Female A*STAR NTU Singapore Singapore [email protected] [email protected] Research Interests: Research Interests: Translational drug discovery for skin blistering condition known asepidermolysis Malaria transcriptomics and genomics; Drug resistance in clinical isolates bullosa simplex using 3D skin equivalents- Understanding the diversity of fibroblasts in healthy skin anddiseased skin conditions such as MSSE.

102 103 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

CORINNE ONG THANH SON NGUYEN

Female PhD student Contact Singapore Male Singapore SMU [email protected] Singapore [email protected] Research Interests: Environmental Sociology, Social Justice, Anthropology, Social Stratification and Research Interests: Inequality, Political Economy Finding a concise representation for entity information in social media.

DENIS NOVITSKY ZHENGXIANG PAN

Male Male Belarus Foundation for Fundamental Research NTU Singapore Singapore [email protected] [email protected]

SZE WEI DANIEL ONG KAUSHIK PARIDA

Male PhD Student A*STAR, Singapore Male [email protected] NTU Heterogeneous Catalysis Singapore [email protected]

Research Interests: Material Science, Nanomaterials, Energy harvesting (Piezoelectric energy harvester), Energy storing (Supercapacitor and battery), Pressure sensors and stretchable electronics.

104 105 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

JOHN POH BOON PIN PEH

Male Male DSO / DSTA DSO / DSTA Singapore Singapore [email protected] [email protected] Research Interests: Research Interests: Management of Technology. Electrical & Electronics Engineering

HONG YONG PEH SRIDHAR PRIYASHRI

Male NUS Female Singapore SUTD [email protected] Singapore Research Interests: [email protected] Optimized an improved murine sub-chronic and chronic obstructive pulmonary disease model with the use of cigarette smoke, Examined the roles Research Interests: of inflammation and oxidative stress in both asthma and COPD, Evaluated Cognitive neuroscience, human‐computer interaction. pulmonary function tests of both asthmatic and COPD mice, Investigated the therapeutic effects of vitamin E in allergic asthma and deduced the pharmacokinetics of vitamin E in mice.

TATIANA PLISKO BOON LI PAMELA PUN

Female Female Belarus Foundation for Fundamental Research DSO / DSTA Singapore Singapore [email protected] [email protected]

Research Interests: To determine if mitochondria and associated oxidative stress causes disease and injury, and whether or how we can protect against such damage.

106 107 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

PARAKALAN RANGARAJAN SIVARAMAN PURUSHOTHUMAN

Male Male NUS Contact Singapore Singapore Singapore [email protected] [email protected] Research Interests: Research Interests: Role of microglia in learning and memory; Sumoylation of inflammatory Neuroscience & Dementia molecules in regulating microglial activation in the rodent brain

SMITHA KAVALLUR PUSHARATH GOPI ZHIHUA REN

NTU Male Singapore SUTD [email protected] Singapore [email protected]

Research Interests: Electromagnetic theories and applications, Magnetic resonance imaging (MRI), /RF devices, antennas.

HONG SHENG QUAH MUHAMMED ESDY NAZIM BIN ROZALI

Male Male NUS Contact Singapore Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: Metal-organic Frameworks. Breast Cancer, Personalised Medicine.

108 109 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

YIRONG SIM MAGDIEL INGGRID SETYAWATI

Female Female SingHealth NUS Singapore Singapore [email protected] [email protected]

Research Interests: Nanomaterials impact on sustainability of modern cities.

ELENA SHABUNYA-KLYACHKOVSKAYA PAVNEET SINGH KOCHHAR

Female Male Belarus Foundation for Fundamental Research SMU Singapore Singapore [email protected] [email protected]

Research Interests: Software testing and bug localization.

KENG BOON SIAH JIA MEI JAMIE SOON

Male Female SembCorp Contact Singapore Singapore Singapore [email protected] [email protected]

Research Interests: Ab initio calculations, material engineering, nanoscience, semiconductor physics, Chemistry.

110 111 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

SAY HWA TAN ZHENGLONG SUN

Male Male Contact Singapore SUTD Singapore Singapore [email protected] [email protected] Research Interests: Research Interests: Droplet/bubbles microfluidics, membrane and interfaces, Lab-on-chips (LOCs) Medical robot/device development and control; Haptic devices and human- and point-of-care diagnostics. machine interaction; Model-based and data-driven based control; Smart sensor design and manufacturing; Machine learning and its application in robotics.

HUI TENG TAN MAXINE HUI YAN TAN

Female Female NTU Contact Singapore Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: The synthesis, characterization and electrochemical performance application Marine Biology with a focus in Genetics of Diatoms. of electro-active materials, including metal oxides, sulfides, and hybrid compounds.

YAW SING TAN WUN KIAT JUSTIN TAN

Male Male A*STAR Contact Singapore Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: Application of computational techniques to the study of biomolecular systems. Systems biology and modelling in prokaryotes with the goals of applying this to Bing Wen, Tan, Male, DSO / DSTA, Singapore, [email protected], Electrical metabolic engineering. & Electronics Engineering.

112 113 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

ALEX TRUKHANOV ANDY TAY KAH PING

Male Male Belarus Foundation for Fundamental Research Contact Singapore Singapore Singapore [email protected] [email protected]

Research Interests: Bioengineering

TECK HUI TEO ADITYA VENKATARAMAN

Male Male A*STAR NTU Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: Effects of Chikungunya virus and Malaria co-infection using suitable murine Power electronics, Microgrid, Renewable energy. models.

SHAMALA THILARAJAH HIM CHENG WONG

Female Male SingHealth SUTD Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: Clinical research that could translate to improving services in the community Nanotechnology, nanolithography and functional materials for sustainability for people living with chronic conditions. research in energy and water.

114 115 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

MING HUI YONG FANG WU

Female Female SingHealth SUTD Singapore Singapore [email protected] [email protected] Research Interests: Research Interests: Neurology. Non-motor symptoms in Parkinson’s disease. Clinical, biochemical Dynamic implementations of magnetic field sensors and imaging systems. and genetic markers in Parkinson’s disease. Stroke reperfusion, stroke risk factors and prognostication.

BO YANG EE JUEN HANNAH YONG

Male Female A*STAR Contact Singapore Singapore Singapore [email protected] [email protected]

Research Interests: Research Interests: Complex systems and non-linear physics, Traffic modelling and optimization, Obstetrics and Gynaecology Next generation intersection control.

KIM THOW YAP LIYA ZHAO

Male PhD Student Keppel Female Singapore NTU [email protected] Singapore [email protected] Research Interests: Clinical research that could translate to improving services in the community Research Interests: Development of Arctic jackup concepts. Calculation of design ice loads on Energy harvesting; smart materials and structures; vibration control. offshore structures. Analysis and design of structures subject to ice loading. Nonlinear finite element Analysis of structures.

116 117 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

MARCO GERLING CHAODONG ZHENG

Male Male Karolinska Institutet NUS Sweden Singapore [email protected] [email protected] Research Interests: Research Interests: Cancer Biology Wireless networks, distributed systems, distributed algorithms.

CHARALAMPOS ANTYPAS TONG GONG

Male Female Karolinska Institutet Karolinska Institutet Sweden Sweden [email protected] [email protected]

Research Interests: Research Interests: Infection diagnostics, antibiotic susceptibility testing, biofilm associated Pediatric epidemiology Infections, biomimetic models.

MUHAMMAD ASGHAR BIANCA TESI

Male Female Karolinska Institutet Karolinska Institutet Sweden Sweden [email protected] [email protected]

Research Interests: Research Interests: Ageing and Infection diseases. Genetic basis of primary immunodeficiencies. Molecular diagnostics based on high-throughput sequencing.

118 119 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

MATEUSZ WIELOPOLSKI ALIREZA JAVADIAN

Male Male Swiss Federal Institute of Technology Swiss Federal Institute of Technology Zurich (ETH Zurich) Zurich (ETH Zurich) Switzerland Switzerland [email protected] [email protected]

Research Interests: Research Interests: Civil Engineering, alternative composite fiber materials as reinforcement Physical chemical and materials sciences, development and analysis of new systems in concrete applications, Structural concrete. materials for applications in photovoltaics, surface technologies, renewable energy sources, building and construction and high performance composites.

MATTHIAS STANDFEST GAO-FONG CHANG

Male Male Swiss Federal Institute of Technology Zurich (ETH Zurich) Taiwan Switzerland [email protected] [email protected]

Research Interests: Convolutional Neural Network, Quadrilateral Mesh Geometries, Urban Morphology, Citizen Science, Social Resilience.

ESTEFANIA TAPIAS WEI-CHAO CHEN

Female Male Swiss Federal Institute of Technology Academia Sinica Zurich (ETH Zurich) Taiwan Switzerland [email protected] [email protected]

Research Interests: Urban planning, Urban climatology, outdoor thermal comfort, measurement networks and urban morphology.

120 121 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

HSIU CHUAN LIN HSIN-HUA CHO

Female Female Academia Sinica Academia Sinica Taiwan Taiwan [email protected] [email protected]

TENG-KUEI HUANG JAKE ACEDERA TAN

Male Male Academia Sinica Academia Sinica Taiwan Taiwan [email protected] [email protected]

CHIA-YING JESSIE KO ZI-FU WANG

Female Male Academia Sinica Academia Sinica Taiwan Taiwan [email protected] [email protected]

122 123 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

PASSAWAN NOPPAKAEW LIEN-SZU WU

Female Female National Science and Technology Development Agency (Thailand) Academia Sinica Thailand Taiwan [email protected] [email protected] Research Interests: Research Interests: Mathematical Sciences Biology of TDP-43 in health and diseases. Epigenetic regulation of activity- dependent gene in neurons.

KROEKKIAT CHINDA JIRAKAN NUNKAEW

Male Female National Science and Technology Development Agency (Thailand) National Science and Technology Development Agency (Thailand) Thailand Thailand [email protected] [email protected]

Research Interests: Research Interests: Physiology Cardiac Electrophysiology Physics

MATTAKA KHONGKOW DAO SUWANSANG JANJAROEN

Female Female National Science and Technology Development Agency (Thailand) National Science and Technology Development Agency (Thailand) Thailand Thailand [email protected] [email protected]

Research Interests: Research Interests: Clinical Medicine Environmental Engineering

124 125 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

SAHAR MOKHLES FILIP BILJECKI

Female Male Erasmus University TU Delft The Netherlands The Netherlands [email protected] [email protected] Research Interests: Research Interests: Lung cancer research 3D Geoinformation, Geographic Information Science (GIS), environmental modelling.

HENG CHI PALWASHA MOKHLES

Male Female Erasmus University Maastricht University The Netherlands The Netherlands [email protected] [email protected]

Research Interests: Research Interests: Clinical research in Hepatology. Visual Impairment and Blindness in Glaucoma.

MATTHIAS FROMMHAGEN RINDIA MAHARANI PUTRI

Male Female Wageningen University University of Twente The Netherlands The Netherlands [email protected] [email protected]

Research Interests: Food Chemistry - Enzymatic plant cell wall deconstruction using oxidative enzymes

126 127 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

WOUTER VIJSELAAR TIES VAN DE LAAR

Male Male University of Twente Wageningen University The Netherlands The Netherlands [email protected] [email protected]

Research Interests: Fundamental and more applied research problems.

FLORIS TEUNIS GERARDUS VAN DEN BRINK EMILY ADLAM

Male PhD Student University of Twente Female The Netherlands University of Cambridge [email protected] United Kingdom [email protected] Research Interests: Chip technologies for drug screening and proteomics. Research Interests: Applied Mathematics and Theoretical Physics (relativistic quantum cryptography).

MARIEKE WILLEMIJN VAN DER HELM JOSEPH BANKS

Female Male University of Twente University of Southampton The Netherlands United Kingdom [email protected] [email protected]

Research Interests: Experimental fluid mechanics to assess the performance of complex deforming geometries in a fluid flow.

128 129 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

SIMON ENGELKE MINGSHENG CHEN

Male Male University of Cambridge Lloyds Register Foundation United Kingdom United Kingdom [email protected] [email protected] Research Interests: Research Interests: Chemistry, physics and materials science (both experimental and Float-over deck installation. Time/frequency domain hydrodynamic analysis. computational), with the aim of improving energy storage technologies. Multi-body hydrodynamic interaction. Stability analysis of floating structures. Offshore moorings and risers. Dynamic analysis of non-linear systems.

FRANCES DAVIS THOMAS FOETS

Female PhD University of Southampton Male United Kingdom University of Cambridge [email protected] United Kingdom [email protected]

THALIA DOMINGUEZ BUCIO KEZIA GAITSKELL

Female Female University of Southampton United Kingdom United Kingdom [email protected] [email protected]

Research Interests: Research Interests: Group IV photonics. Development of material platforms based on silicon and Epidemiology, Population Health, Pathology, Cancer. other group IV materials.

130 131 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

DOMANIÇ LAVERY HAJAR HAJMOHAMMADI HOSSEINABADI

Male Female University College London Lloyds Register Foundation United Kingdom United Kingdom [email protected] [email protected] Research Interests: Research Interests: Novel optical communications systems to significantly increase the data rates Transportation engineering. Optimising operations and management of multi- modal urban transport systems for environmental improvement. Statistical of fibre optic networks. analysis and modelling of vehicle emissions. Traffic management based on microsimulation and vehicle emission model

SABINA HATCH MARCO LORENZI

Female Male University College London University College London United Kingdom United Kingdom [email protected] [email protected]

Research Interests: Research Interests: Designing and fabricating nanostructures to increase the efficiency of solar Machine/ Statistical Learning, Signal/Image processing, Medical Imaging, cells. Differential Geometry.

TZU-YI HUNG HARRY-LUKE OLIVER MCCLELLAND

Female Male, Roll-Royce University of Oxford United Kingdom United Kingdom [email protected] [email protected]

Research Interests: Biogeochemical cycles, Palaeoclimate, Evolutionary biology, Isotope geochemistry.

132 133 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

SAMUEL POWELL ROBERT MURRAY

Male Male University College London University of Southampton United Kingdom United Kingdom [email protected] [email protected] Research Interests: Static and dynamic image reconstruction techniques in diffuse optical tomography, and hybrid techniques such as ultrasound-modulated optical tomography and photo-acoustic tomography.

LUCA PERUZZOTTI-JAMETTI LINUS JULIAN SCHUMACHER

Male Male MD - University Vita-Salue San Raffaele, University of Cambridge University of Oxford United Kingdom United Kingdom [email protected] [email protected]

Research Interests: Research Interests: Neurology Collective behaviour, Developmental biology, Neuroscience, Statistical mechanics.

BEN PILGRIM MILENA STUDIC

Male Female University of Cambridge Lloyds Register Foundation United Kingdom United Kingdom [email protected] [email protected] Air traffic and transport engineering Research Interests: Organic chemistry, supramolecular chemistry, self-assembly, synthesis, Research Interests: heterocycles, catalysis Airport apron and ground-handling safety. Fatigue and flight crew workload analysis. Assessment of the evolution of the European air travel environment. Resilience engineering in complex socio-technical systems.

134 135 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

BONNIE VAN WILGENBURG ADRIAN TAN WEI YEE

Female Male University of Oxford Roll-Royce United Kingdom United Kingdom [email protected] [email protected] Research Interests: Research Interests: Immunology Virology Particle impact physics, bonding mechanism and fluid dynamics of the particle-gas flow.

PATRICK THILL AADEEL AKHTAR

Male Male University of Oxford University of Illinois at Urbana-Champaign United Kingdom United States of America [email protected] Research Interests: Research Interests: MD/PhD Neuroscience Sustainability, Water, Resource Recovery, Energy

SOEREN SLOTH THOMSEN DANQING (JESSIE) CAI

Male SAP University of Oxford United States of America United Kingdom [email protected] [email protected] Research Interests: Research Interests: Technology feasibility, solution scalability and market readiness through field Translational medicine, Genomics, Systems biology, Type 2 diabetes. researches, prototype developments and evaluations.

136 137 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

CARLOS DUARTE GUEVARA CARLOS CASTRO-GONZALEZ

Male Male University of Illinois at Urbana-Champaign Massachusetts Institute of Technology United States of America United States of America [email protected] [email protected] Research Interests: Research Interests: Electrical Engineering. Field-effect transistor biosensing. Food safety. Biomedical applications of image/signal processing, machine learning, data Microfluidics. science and data visualization.

RAN CHAO AANCHAL GOYAL

Male PhD in Applied Mathematics University of Illinois at Urbana-Champaign Female United States of America IBM, United States of America [email protected] [email protected]

Research Interests: Research Interests: Chemical and Biomolecular Engineering Synthetic Biology Lab Automation. Smarter Energy

CLAIRE CONWAY STEPHAN HOLZER

Female Male Massachusetts Institute of Technology Massachusetts Institute of Technology United States of America United States of America [email protected] [email protected]

Research Interests: Research Interests: Understanding the computational structural response of healthy and diseased The theory of distributed systems. arterial tissue to intravascular stent implantation.

138 139 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

LINDAWATI DOLAANA KHOVALYG

Female Female SAP University of Illinois at Urbana-Champaign United States of America United States of America [email protected] [email protected] Research Interests: Research Interests: Urban Logistics. Automated Parameter Tuning. Operation Research Industry Mechanical Engineering Application.

BOMY LEE CHUNG YUHAO LIU

Female Male Massachusetts Institute of Technology University of Illinois at Urbana-Champaign United States of America United States of America [email protected] [email protected]

Research Interests: Research Interests: Statin-loaded Lipid-Polymer Nanoparticles for Anti-Inflammatory Therapy. Materials Science and Engineering, Advanced Biomedical Sensors, Flexible and Stretchable Devices, Semiconductor Processing.

CHONG-U LIM PENG NI

Male Male Massachusetts Institute of Technology SAP United States of America United States of America [email protected] [email protected]

Research Interests: Research Interests: Developing Computational Models in Digital Media for Social Analysis and User Dynamic and real-time trip planning for intelligent transport systems for smart Empowerment. cities, especially for public transport systems.

140 141 YOUNG SCIENTISTS INDEX YOUNG SCIENTISTS INDEX

CHEN WANG ERICK ODOUR

Male Male SAP IBM United States of America United States of America [email protected] [email protected] Research Interests: Mathematical optimization, data analysis and their applications in Smart City, Internet of Things (IoT), urban logistics, process systems and operations management.

KHASFARIYATI BINTE RAZIKIN LANJUN WANG

Female PhD in Electronic Engineering, SAP Female United States of America IBM [email protected] United States of America [email protected]

Research Interests: Data management

HOANG TAM VO HAODAN YANG

Ph.D. in Computer Science Female Male SAP SAP United States of America United States of America [email protected] [email protected] Research Interests: Online consumer behaviours, online product marketing and social networks related topics.

142 143 YOUNG SCIENTISTS INDEX

NHAN HA

Male SaigonScienists Vietnam [email protected]

Research Interests: Synthesis and elaboration of composite and nanocomposite based on polymer and natural fillers. Synthesis and elaboration of biodegradable/ biocompatible or antibacterial materials.

CHUONG NGUYEN

Male INTERNATIONAL SaigonScienists Vietnam [email protected] ADVISORY Research Interests: Computational and Molecular Biophysics. COMMITTEE

HANH TRAN

Female SaigonScienists Vietnam [email protected]

Research Interests: Bioprocess engineering; microbiology

144 INTERNATIONAL ADVISORY COMMITTEE INTERNATIONAL ADVISORY COMMITTEE

PROF MICHAEL GRÄTZEL PROF TAN CHORH CHUAN

Millennium Technology Prize (2010) President, National University of Singapore

SIR RICHARD ROBERTS PROF BERTIL ANDERSSON

Nobel Prize in Physiology or Medicine (1993) President, Nanyang Technological University

PROF EI-ICHI NEGISHI PROF ARNOUD DE MEYER

Nobel Prize in Chemistry (2010) President, Singapore Management University

PROF CLAUDE COHEN-TANNOUDJI PROF THOMAS MAGNANTI

Nobel Prize in Physics (1997) President, Singapore University of Technology and Design

PROF ANDREW YAO

Turing Award (2000)

146 147