Washington University Record, January 15, 2009
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Washington University School of Medicine Digital Commons@Becker Washington University Record Washington University Publications 1-15-2009 Washington University Record, January 15, 2009 Follow this and additional works at: http://digitalcommons.wustl.edu/record Recommended Citation "Washington University Record, January 15, 2009" (2009). Washington University Record. Book 1164. http://digitalcommons.wustl.edu/record/1164 This Article is brought to you for free and open access by the Washington University Publications at Digital Commons@Becker. It has been accepted for inclusion in Washington University Record by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. Medical News: BJC Institute 'Masked Marvels': Innovative Washington People: Cobb seeks of Health at WUSTL on schedule show for 'young people' series to return critically ill patients to health 8 Washington University in St Louis Jan. 15, 2009 record.wustl.edu Estrogen can benefit women with metastatic breast cancer BY GWEN ERICSON "By stabilizing or shrinking tumors in some wom- en with metastatic breast cancer, estrogen <therapy can For breast cancer survivors, the idea of taking relieve pain and other symptoms of cancer and can estrogen pills is almost a taboo. In fact, their potentially prolong lives," said Ellis, an oncologist doctors give them drugs to get rid of the hor- with the Siteman Cancer Center. "And, unlike chemo- mone because it can fuel the growth of breast cancer. therapy, estrogen enhances the quality of life. For So these women probably would be surprised by many of our patients, their hot flashes disappear, and the approach taken by breast cancer physician they lose other symptoms of menopause. It's a natural Matthew Ellis, M.D., Ph.D., associate professor of treatment for breast cancer. Not only that, it's much medicine at the School of Medicine, who has demon- cheaper than chemotherapy, costing less than a dollar strated that estrogen therapy can help control meta- a day." static breast cancer. Furthermore, estrogen seems able to return meta- In a study presented at the 31st annual San Antonio static tumors to a vulnerable state in which they again Breast Cancer Symposium, Ellis showed that for about can be affected by aromatase inhibitors. a third of the 66 participants — women with metastatic "We thought acquired resistance to aromatase breast cancer that had developed resistance to standard inhibitor therapy was permanent," Ellis said. "But estrogen-lowering therapy — a daily dose of estrogen now we've shown that in some patients giving estro- could stop the growth of tumors or even cause them to gen can make it possible to cycle back to aromatase shrink. The study was funded by the Avon Foundation inhibitors, and they can work again." through the National Cancer Institute and included six About 40,000 women die of metastatic breast cancer centers in the United States. cancer each year, and estrogen therapy potentially Ellis said estrogen therapy offers an appealing could help thousands of women with hormone recep- alternative to chemotherapy for metastatic breast . tor-positive disease, Ellis said. cancer that has become resistant to estrogen-lowering The study measured how many women with aro- agents called aromatase inhibitors. These drugs de- matase inhibitor therapy-resistant metastatic breast plete the body of estrogen and are standard treat- cancer responded to estrogen therapy. All study par- ments for hormone-receptor positive breast cancers, ticipants had estrogen-receptor positive tumors that which account for about 75 percent of breast cancer had spread to their bones, livers or lungs. The women cases. See Estrogen, Page 6 Check your risk of major diseases with new, secure tool BY BETH MILLER diabetes and osteoporosis and to able to return to the site and track learn prevention strategies. their results and certain behaviors A fter spending summer week- To start, users log onto over time, a function not available Wends at the pool, have you ever yourhealthsnapshot.wustl.edu and on Your Disease Risk. A crew from Global Technical Systems Inc. installs an emergency siren on the roof of Brookings Hall Jan. 5. A siren also was installed wondered about your risk for skin answer simple questions about The University's Wellness on the roof of Seigle Hall. The sirens will be painted gray or sky-blue cancer? Ever wondered if your their medical history, eating hab- Council has worked with Colditz this spring to better blend in against the landscape. great-grandmothers diabetes its, exercise and other behaviors. to create a tool specifically for increases your risk for the disease? The result is a personalized esti- faculty, staff and students to be Now, an easy and secure Internet mate of a persons risk for these used to measure the health of its New Danforth Campus tool determines your risk with just diseases. community. The site's health infor- a few clicks of a mouse: Your What sets Your Health - mation is backed by recent evi- Health Snapshot. Snapshot apart from Your Disease dence from the medical commu- sirens another form of Modeled after Your Disease Risk is the addition of a very brief nity to assure that users are up to Risk, created by Graham Colditz, opening questionnaire and the date. emergency communication M.D., Ph.D., the Niess-Gain ability to create a personal user "Your Health Snapshot should Professor of Surgery, professor of account. The 15-20 item opening be a great tool for helping people BY JESSICA DAUES e-mails, the emergency Web site medicine and associate director of questionnaire provides a quick lead healthier lives," Colditz said. (emergency.wustl.edu) and an Prevention and Control at Siteman overview of a person's risk of six "In addition to being able to find Washington University installed emergency hotline (935-9000 Cancer Center, Your Health key diseases and acts as a guide out their risk of diseases like can- warning sirens on the roofs of locally or toll-free 888-234-2863). Snapshot is a confidential site that that shows which diseases some- cer, heart disease, diabetes and Brookings Hall and Seigle Hall WUSTL community members members of the Washington one may want to explore further osteoporosis, the site offers per- Jan. 5. A third siren will be in- can sign up to receive text mes- University community can use to on the site. sonalized tips for lowering risks as stalled on a building in the South sages on their cells phones at determine their risk for various The addition of personal user well as positive feedback on things 40 this spring. emergency.wustl.edu. cancers, stroke, heart disease, accounts means that users will be See Risk, Page 2 The sirens, part of WUSTL's "The University is working Emergency Notification System, hard not to rely on any one mode broadcast both warning tones and of communication in an emer- voice messages and will be used to gency," said Matthew Arthur, Campus ready for another round of RecycleMania alert the campus to severe weather, director of incident communica- Challenge is to reduce, reuse, recycle and build on last year's success hazardous-material spills, fires, tions solutions. "The presence of violence on campus or other emer- sirens on the Danforth Campus BY JESSICA DAUES No. 9 (out of 99) among private While the campus encourages gency situations. Once all three adds to the University's ability to colleges and universities and recycling at all times, all faculty, sirens are in place, emergency get information to as many people WUSTL's No. 21 national rank- No. 21 overall (out of 200) in the staff and students are strongly messages will be audible outdoors as possible as quickly as possible." ing in last year's RecycleMania annual RecycleMania contest's encouraged to reduce, reuse and throughout the Danforth Campus. Other universities that use siren competition was impressive, but Gorilla category, which is based on recycle during the competition to "When alerting the community systems similar to WUSTL's in- the Office of Sustainability is chal- total recycled materials collected. re-emphasize the importance of of a crisis, early notification is clude Northwestern University, lenging WUSTL to finish even The University recycled more reducing landfill waste and to help critical," said Bruce Backus, assis- Cornell University, Ithaca College higher in the 2009 RecycleMania than 21 pounds per person over WUSTL defeat fellow schools. tant vice chancellor for environ- and the University of New contest, which begins Sunday, the course of the competition. For The University first partici- mental health and safety. Hampshire. Jan. 18. its efforts, WUSTL was recognized pated in RecycleMania in 2003, "The use of sirens, along with If an emergency occurs, a siren RecycleMania is an annual in December 2008 with an Excel- the contests third year, when other means of emergency com- will sound, and a voice will briefly competition administered by the lence Award from the Missouri WUSTL ranked last among eight munication, will help to quickly describe the nature of the emer- National Recycling Coalition. It Recycling Association. competing schools in the Per inform the community of an emer- gency. Though the voice may pits WUSTL against other U.S. "RecycleMania is a terrific Capita award, which measures the gency and help students, faculty, provide instructions, the colleges and universities to see competition," said Matt Malten, amount of recycled goods per staff and visitors take appropriate University community should which campus can prevent the assistant vice chancellor for sus- person. WUSTL has dramatically action to keep themselves and review information about what to most materials from being buried tainability. "It serves to remind us improved its standing since then, their colleagues safe," Backus said. do in a particular situation before in a landfill.