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INTRODUCTION TO MOLECULAR UMDNJ-RUTGERS UNIVERSITY

COURSE TITLE: Introduction to Molecular medicine COURSE NUMBER: GSBS = MICR-6003 and RU= 16:681:530 CREDIT HOURS: 3 hours WHERE: Research Tower, 6th floor conference room TIME: 3:00-4:30pm, Wednesday and Friday

DESCRIPTION: The emerging field of molecular medicine provides deeper understanding of diseases and offers opportunities for designing rational . “Introduction to Molecular Medicine” is designed to introduce students to topics in human health and disease from a perspective. Basic principles that promote an understanding of the human genome, gene regulation and expression, and genetic engineering will be applied to the diagnosis and treatment of human disease. Lectures will be followed by discussion of a published article of interest. Format will be two classes per week, with the lecture in one class followed by a discussion on prescribed papers in the next class.

COURSE Debabrata Banerjee, Ph.D. Emine Abali, Ph.D. DIRECTORS: The Institute of New Jersey RWJMS And Molecular Biology Office: 3035 Phone: 732-235-6458 Office: R527 Phone: 732-235-3911 [email protected] [email protected]

TEXTBOOKS: no textbook required. The lecturers will provide you with their powerpoint presentations and 2 articles on the subject.

Speaker Dates Topic Send PPT Student and the Presenter Papers by s Wednesday-January 23 Introduction Vikas Nanda Friday January 25- Molecular modeling in Jan 18 Wednesday-January 30 Medicine Arash Hatefi Friday February 1 Applications of Jan 25 Wednesday-February 6 nanotechnology in human health and disease Jim Millonig Friday February 8 Autism Feb 1 Wednesday-February 13 Friday February 15 Hematological Feb 8 Mecide Gharibo Wednesday-February 20 Malignancies

Sharon Pine Friday February 22 Cancer Stem Cells Feb 15 Wednesday-February 27 John Glod Friday March 1 Pediatric Head and Feb 22 Wednesday-March 6 Neck

WenWei Hu Friday March 8 The p53 family in health Mar 8 Wednesday-March 13 and disease SPRING BREAK March 16-March 24

Debabrata Banerjee Wednesday-March 27 Mesenchymal Stem Mar 20 cells GOOD FRIDAY

Debabrata Banerjee Wednesday-April 3 Mesenchymal Stem cells Paul Copeland Friday April 5 RNA Therapeutics Mar 29 Wednesday-April 10 Michael Matise Friday April 12 Role of the Hedgehog April 5 Wednesday-April 17 (Hh) pathway in central nervous system (CNS) development Kim Hirshfield Friday April 19 Single Nucleotide April 12 Wednesday-April 24 Polymorphisms and Cancer Sridar Ganesan Wednesday April 26 Cancer April 19 Friday-May 1 Steve Zheng Wednesday May 3 mTOR April 26 Friday-May 8 Spring Exams Begin

ASSESMENT: The students will be graded for their presentations and participation. There will be no exams. Each lecturer will provide us with two papers, and two students will present on Fridays the papers. While one student should prepare an introduction to the topics and a review of the techniques used in the papers, the other student should present the papers.

Either one or both of the course directors will be present in all lectures to determine the level of participation in the class.