Predictors of Mortality among TB-HIV Co-Infected Children Attending Anti-Retroviral Therapy Clinics of Selected Public Hospitals in Southern, Ethiopia: Retrospective Cohort Study Jifare Gemechu Wachemo University Bereket Gebremichael Addis Ababa University Tewodros Tesfaye Addis Ababa University Alula Seyum Wachemo University Desta Erkalo (
[email protected] ) Wachemo University https://orcid.org/0000-0001-5981-439X Research Keywords: TB-HIV/AIDS, Mortality, Children, Anti-Retroviral Therapy Posted Date: July 19th, 2021 DOI: https://doi.org/10.21203/rs.3.rs-704349/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Loading [MathJax]/jax/output/CommonHTML/jax.js Page 1/26 Abstract Background: Co-infection of tuberculosis and HIV has a signicant impact on public health. TB is the most common opportunistic infection and the leading cause of death in HIV-positive children worldwide. But there is paucity of studies concerning the predictors of mortality among TB-HIV co-infected children. This study aimed to determine the predictors of mortality among TB-HIV co-infected children attending ART clinics of public hospitals in Southern Nation, Nationalities and Peoples Region (SNNPR), Ethiopia. Methods: A hospital-based retrospective cohort study design was used among 284 TB-HIV co-infected children attending ART clinics at selected public hospitals in SNNPR, Ethiopia, from January 2009 to December 2019. Then, medical records of children who were TB/HIV co-infected and on ART were reviewed using a structured data extraction tool. Data were entered using Epidata 4.6 and analyzed using SPSS version 23. The Kaplan Meier survival curve along with log rank tests was used to estimate and compare survival time.