PROPOSED REGULATION of the STATE BOARD of HEALTH LCB File No. R057-16
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Glossary for Narrative Writing
Periodontal Assessment and Treatment Planning Gingival description Color: o pink o erythematous o cyanotic o racial pigmentation o metallic pigmentation o uniformity Contour: o recession o clefts o enlarged papillae o cratered papillae o blunted papillae o highly rolled o bulbous o knife-edged o scalloped o stippled Consistency: o firm o edematous o hyperplastic o fibrotic Band of gingiva: o amount o quality o location o treatability Bleeding tendency: o sulcus base, lining o gingival margins Suppuration Sinus tract formation Pocket depths Pseudopockets Frena Pain Other pathology Dental Description Defective restorations: o overhangs o open contacts o poor contours Fractured cusps 1 ww.links2success.biz [email protected] 914-303-6464 Caries Deposits: o Type . plaque . calculus . stain . matera alba o Location . supragingival . subgingival o Severity . mild . moderate . severe Wear facets Percussion sensitivity Tooth vitality Attrition, erosion, abrasion Occlusal plane level Occlusion findings Furcations Mobility Fremitus Radiographic findings Film dates Crown:root ratio Amount of bone loss o horizontal; vertical o localized; generalized Root length and shape Overhangs Bulbous crowns Fenestrations Dehiscences Tooth resorption Retained root tips Impacted teeth Root proximities Tilted teeth Radiolucencies/opacities Etiologic factors Local: o plaque o calculus o overhangs 2 ww.links2success.biz [email protected] 914-303-6464 o orthodontic apparatus o open margins o open contacts o improper -
Heart Tumors in Domestic Animals
HEART TUMORS IN DOMESTIC ANIMALS Marko Hohšteter Department of veterinary pathology, Veterinary Faculty University of Zagreb Neoplasms of the heart are rare diseases in domestic animals. Among all domestic animals heart neoplasm are most common in dogs. Most of the canine heart tumors are primary what is contrary to other domestic animals, in which most of cardiac tumors are metastatic. Primary tumors of the heart represent 0,69% of the canine tumors. Among all primary neoplasms canine hemangiosarcoma of the right atrium is the most common. Other primary cardiac tumors in domestic animals include rhabdomyoma, rhabdomyosarcoma, myxoma, myxosarcoma, chondrosarcoma, osteosarcoma, granular cell tumor, fibroma, fibrosarcoma, lipoma, pericardial mesothelioma and undifferentiated sarcoma. Aortic and carotid body tumors are usually classified under primary heart neoplasm but are actually tumors which arise in adventitia or periarterial adipose tissue of the aorta, carotid artery or pulmonary artery, and can extend to heart base. Hemangiosarcoma is the most important and most frequent cardiac neoplasm of dogs. This tumor develops primary from the blood vessels that line the heart or can matastasize from sites such as spleen, skin or liver. It is most commonly reported in mid to large breeds, such as boxers, German shepherds, golden retrievers, and in older dogs (six years and older). Aortic and carotide body adenoma and adenocarcinoma belong into the group of chemoreceptor tumors („chemodectomas“) and are morphologicaly similar. In animals, incidence of aortic body neoplasm is higher than that of the carotide body. Both tumors mostly develop in dogs (brachyocephalic breed: boxers, Boston teriers), and are rare in cats and cattle. -
Mixed Hepatoblastoma in the Adult: Case Report and Review of the Literature
J Clin Pathol: first published as 10.1136/jcp.33.11.1058 on 1 November 1980. Downloaded from J Clin Pathol 1980;33:1058-1063 Mixed hepatoblastoma in the adult: case report and review of the literature RP HONAN AND MT HAQQANI From the Department of Pathology, Walton Hospital, Rice Lane, Liverpool L9 JAE, UK SUMMARY A case of mixed hepatoblastoma in a woman is described. A survey of the English literature reveals 13 cases acceptable as mixed hepatoblastoma; these have been described and published under a variety of names. Difficulties in nomenclature and the histology of these cases are discussed. Diagnosis depends on the identification of both malignant mesenchymal and malignant epithelial elements. The former include myxoid connective tissue resembling primitive mesenchyme and areas resembling adult fibrosarcoma. Mature fibrous tissue with calcification and bone for- mation may be seen. Epithelial areas show tissue resembling fetal liver, poorly differentiated epithelial cells, and/or areas of adenocarcinoma. The current view on histogenesis is also given. Most hepatoblastomas occur in children under the mixedtumour,6carcino-osteochondromyxosarcoma,5 copyright. age of 2 years.' Hepatoblastoma in adults is ex- and rhabdomyosarcohepatoma.7 tremely rare, and the prognosis is much worse than in the mixed hepatoblastoma of childhood. Case report The literature of mixed hepatoblastoma in adults has until recently been confused, and the true inci- CLINICAL PRESENTATION dence of the tumour obscured, owing to the various A Chinese woman aged 27 had been resident in names used by different authors to describe their England for eight years. She gave a history of cases. The commonest pseudonym is 'mixed malig- 18 months' intermittent right-sided chest pain http://jcp.bmj.com/ nant tumour',2-4 an ambivalent term which merely and upper abdominal discomfort. -
The Health-Related Quality of Life of Sarcoma Patients and Survivors In
Cancers 2020, 12 S1 of S7 Supplementary Materials The Health-Related Quality of Life of Sarcoma Patients and Survivors in Germany—Cross-Sectional Results of A Nationwide Observational Study (PROSa) Martin Eichler, Leopold Hentschel, Stephan Richter, Peter Hohenberger, Bernd Kasper, Dimosthenis Andreou, Daniel Pink, Jens Jakob, Susanne Singer, Robert Grützmann, Stephen Fung, Eva Wardelmann, Karin Arndt, Vitali Heidt, Christine Hofbauer, Marius Fried, Verena I. Gaidzik, Karl Verpoort, Marit Ahrens, Jürgen Weitz, Klaus-Dieter Schaser, Martin Bornhäuser, Jochen Schmitt, Markus K. Schuler and the PROSa study group Includes Entities We included sarcomas according to the following WHO classification. - Fletcher CDM, World Health Organization, International Agency for Research on Cancer, editors. WHO classification of tumours of soft tissue and bone. 4th ed. Lyon: IARC Press; 2013. 468 p. (World Health Organization classification of tumours). - Kurman RJ, International Agency for Research on Cancer, World Health Organization, editors. WHO classification of tumours of female reproductive organs. 4th ed. Lyon: International Agency for Research on Cancer; 2014. 307 p. (World Health Organization classification of tumours). - Humphrey PA, Moch H, Cubilla AL, Ulbright TM, Reuter VE. The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part B: Prostate and Bladder Tumours. Eur Urol. 2016 Jul;70(1):106–19. - World Health Organization, Swerdlow SH, International Agency for Research on Cancer, editors. WHO classification of tumours of haematopoietic and lymphoid tissues: [... reflects the views of a working group that convened for an Editorial and Consensus Conference at the International Agency for Research on Cancer (IARC), Lyon, October 25 - 27, 2007]. 4. ed. -
Pediatric Abdominal Masses
Pediatric Abdominal Masses Andrew Phelps MD Assistant Professor of Pediatric Radiology UCSF Benioff Children's Hospital No Disclosures Take Home Message All you need to remember are the 5 common masses that shouldn’t go to pathology: 1. Infection 2. Adrenal hemorrhage 3. Renal angiomyolipoma 4. Ovarian torsion 5. Liver hemangioma Keys to (Differential) Diagnosis 1. Location? 2. Age? 3. Cystic? OUTLINE 1. Kidney 2. Adrenal 3. Pelvis 4. Liver OUTLINE 1. Kidney 2. Adrenal 3. Pelvis 4. Liver Renal Tumor Mimic – Any Age Infection (Pyelonephritis) Don’t send to pathology! Renal Tumor Mimic – Any Age Abscess Don’t send to pathology! Peds Renal Tumors Infant: 1) mesoblastic nephroma 2) nephroblastomatosis 3) rhabdoid tumor Child: 1) Wilm's tumor 2) lymphoma 3) angiomyolipoma 4) clear cell sarcoma 5) multilocular cystic nephroma Teen: 1) renal cell carcinoma 2) renal medullary carcinoma Peds Renal Tumors Infant: 1) mesoblastic nephroma 2) nephroblastomatosis 3) rhabdoid tumor Child: 1) Wilm's tumor 2) lymphoma 3) angiomyolipoma 4) clear cell sarcoma 5) multilocular cystic nephroma Teen: 1) renal cell carcinoma 2) renal medullary carcinoma Renal Tumors - Infant 1) mesoblastic nephroma 2) nephroblastomatosis 3) rhabdoid tumor Renal Tumors - Infant 1) mesoblastic nephroma 2) nephroblastomatosis 3) rhabdoid tumor - Most common - Can’t distinguish from congenital Wilms. Renal Tumors - Infant 1) mesoblastic nephroma 2) nephroblastomatosis 3) rhabdoid tumor Look for Multiple biggest or diffuse and masses. ugliest. Renal Tumors - Infant 1) mesoblastic -
Partners in Care – January 2017
The newSEE CE Schedule INSIDE & on a Referralremovable Contact postcard! Info Partners In Care Veterinary Referral News from Angell Animal Medical Center Winter 2017 π Volume 11:1 π angell.org π facebook.com/AngellReferringVeterinarians PRE-HOSPITAL EYELID MARGIN SEDATION OPTIONS BUILDING A RADIOGRAPHIC TUMOR GRADING— MASSES IN DOGS: FOR AGGRESSIVE AND CONFIDENT PUPPY APPROACH TO IS IT APPLICABLE? TO CUT OR ANXIOUS DOGS BONE IMAGING NOT TO CUT? PAGE 1 PAGE 1 PAGE 4 PAGE 6 PAGE 8 ANESTHESIA BEHAVIOR Pre-Hospital Sedation Building a Options for Aggressive Confident Puppy and Anxious Dogs π Terri Bright, Ph.D., BCBA-D, CAAB π Kate Cummings, DVM, DACVAA angell.org/behavior [email protected] angell.org/anesthesia 617-989-1520 [email protected] 617-541-5048 ggressive and/or fearful dogs present several challenges for the othing makes everyone happier than having puppies in the small animal practitioner. These patients are difficult to fully veterinary office. The client brings the pup soon after they evaluate and present a safety hazard to the clinic staff, purchase or adopt it to make sure it is healthy, and to begin the veterinarian, and sometimes even the owner. In addition, a process of vaccinations and a lifetime of health. Everyone oohs Anervous dog contributes to heightened stress within the work area affecting Nand ahs over it, but what are the most important things a vet and their staff not only people, but other pets alike. In dogs known to be aggressive within can do to make sure the pup grows up to be happy and behaviorally healthy? the hospital setting or those with tremendous fear/anxiety, making physical exams and basic assessment impossible, pre-hospital sedation can First, find out what the puppy’s history is. -
NY-ESO-1 (CTAG1B) Expression in Mesenchymal Tumors
Modern Pathology (2015) 28, 587–595 & 2015 USCAP, Inc. All rights reserved 0893-3952/15 $32.00 587 NY-ESO-1 (CTAG1B) expression in mesenchymal tumors Makoto Endo1,2,7, Marieke A de Graaff3,7, Davis R Ingram4, Simin Lim1, Dina C Lev4, Inge H Briaire-de Bruijn3, Neeta Somaiah5, Judith VMG Bove´e3, Alexander J Lazar6 and Torsten O Nielsen1 1Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada; 2Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan; 3Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands; 4Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 5Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA and 6Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA New York esophageal squamous cell carcinoma 1 (NY-ESO-1, CTAG1B) is a cancer-testis antigen and currently a focus of several targeted immunotherapeutic strategies. We performed a large-scale immunohistochemical expression study of NY-ESO-1 using tissue microarrays of mesenchymal tumors from three institutions in an international collaboration. A total of 1132 intermediate and malignant and 175 benign mesenchymal lesions were enrolled in this study. Immunohistochemical staining was performed on tissue microarrays using a monoclonal antibody for NY-ESO-1. Among mesenchymal tumors, myxoid liposarcomas showed the highest positivity for NY-ESO-1 (88%), followed by synovial sarcomas (49%), myxofibrosarcomas (35%), and conventional chondrosarcomas (28%). Positivity of NY-ESO-1 in the remaining mesenchymal tumors was consistently low, and no immunoreactivity was observed in benign mesenchymal lesions. -
Variants of Acinar Adenocarcinoma of the Prostate Mimicking Benign Conditions Peter a Humphrey
Modern Pathology (2018) 31, S64–S70 S64 © 2018 USCAP, Inc All rights reserved 0893-3952/18 $32.00 Variants of acinar adenocarcinoma of the prostate mimicking benign conditions Peter A Humphrey Department of Pathology, Yale School of Medicine, New Haven, CT, USA Histological variants of acinar adenocarcinoma of the prostate may be of significance due to difficulty in diagnosis or due to differences in prognosis compared to usual acinar adenocarcinoma. The 2016 World Health Organization classification of acinar adenocarcinoma includes four variants that are deceptively benign in histological appearance, such that a misdiagnosis of a benign condition may be made. These four variants are atrophic pattern adenocarcinoma, pseudohyperplastic adenocarcinoma, microcystic adenocarcinoma, and foamy gland adenocarcinoma. They differ from usual small acinar adenocarcinoma in architectural glandular structure and/or cytoplasmic and nuclear alterations. The variants are often admixed, in variable proportions, with usual small acinar adenocarcinoma that is often Gleason pattern 3 but may be high-grade pattern 4 in a minority of cases. Atrophic pattern adenocarcinoma can be identified in a sporadic setting or after radiation or hormonal therapy. This variant is characterized by cytoplasmic volume loss and can resemble benign glandular atrophy, an extremely common benign process in the prostate. The glands of pseudohyperplastic adenocarcinoma simulate usual epithelial hyperplasia, with gland complexity that is not typical of small acinar adenocarcinoma. These complex growth configurations include papillary infoldings, luminal undulations, and branching. Microcystic adenocarcinoma is characterized by cystic dilation of prostatic glands to a size that is much more commonly observed in cystic change in benign prostatic glands. Finally, the cells in foamy gland adenocarcinoma display cytoplasmic vacuolization and nuclear pyknosis, features that can found in benign glands and macrophages. -
Supplementary Table 1) Immunohistochemical Protocol and Antibody Information Antibody Company Clone/# Clonality Dilution Incubat
H. Reis et al: Differential proteomic and tissue expression analyses identify valuable diagnostic biomarkers of hepatocellular differentiation and hepatoid adenocarcinomas Suppl ementary Table 1) Immunohistochemical protocol and antibody information Antibody Company Clone/# Clonality Dilution Incubation Antigen retrieval Detection ABAT Abcam EPR4433 mono 1/3000 30 min, RT pH 9.0, WB, 95°C, 20 min. Zytomed Polymer HRP ACAA2 Abcam EPR6733 mono 1/100 30 min, RT pH 9.0, WB, 95°C, 20 min Zytomed Polymer HRP ACADM Abcam EPR3708 mono 1/3000 30 min, RT pH 9.0, WB, 95°C, 20 min Zytomed Polymer HRP ADH1B Abcam 4F12 mono 1/12.000 30 min, RT pH 9.0, WB, 95°C, 20 min Zytomed Polymer HRP Arginase1 Abcam EPR6672(B) mono 1/1000 30 min, RT pH 9.0, WB, 95°C, 20 min. Zytomed Polymer HRP BHMT Abcam EPR6782 mono 1/100 30 min, RT pH 9.0, WB, 95°C, 20 min. Zytomed Polymer HRP FABP1 Acris AIV\09011PU-S mono 1/15.000 30 min, RT pH 9.0, WB, 95°C, 20 min. Zytomed Polymer HRP HAOX1 Acris AP18044PU-N poly 1/100 30 min, RT pH 9.0, WB, 95°C, 20 min. Zytomed Polymer HRP HepPar1 Dako OCH1E5 mono 1/800 30 min, RT pH 9.0, WB, 95°C, 20 min. Zytomed Polymer HRP HMGCS2 Abcam Ab104807 poly 1/50 60 min, RT pH 9.0, WB, 95°C, 20 min Zytomed Polymer HRP H. Reis et al: Differential proteomic and tissue expression analyses identify valuable diagnostic biomarkers of hepatocellular differentiation and hepatoid adenocarcinomas Supplementary Table 2) Composition of the non-liver tumor TMA Diagnosis n % ADC 11 2.9 ADC Adenocarcinoma of the lung Carc. -
1 Effective January 1, 2018 ICD‐O‐3 Codes, Behaviors and Terms Are Site‐Specific Alpha Order Last Updat
Effective January 1, 2018 ICD‐O‐3 codes, behaviors and terms are site‐specific Alpha Order Last updated 8/22/18 Status ICD‐O‐3 Term Reportable Comments Morphology Y/N Code New Term 8551/3 Acinar adenocarcinoma (C34. _) Y Lung primaries diagnosed prior to 1/1/2018 use code 8550/3 For prostate (all years) see 8140/3 New Term 8140/3 Acinar adenocarcinoma (C61.9 ONLY) Y For prostate only, do not use 8550/3 New Term 8572/3 Acinar adenocarcinoma, sarcomatoid (C61.9) Y New Term 8550/3 Acinar cell carcinoma Y Excludes C61.9‐ see 8140/3 New Term 8316/3 Acquired cystic disease‐associated renal cell carcinoma (RCC) Y (C64.9) New 8158/1 ACTH‐producing tumor N code/term New Term 8574/3 Adenocarcinoma admixed with neuroendocrine carcinoma (C53. _) Y Behavior 8253/2 Adenocarcinoma in situ, mucinous (C34. _) Y Important note: lung Code/term primaries ONLY: For cases diagnosed 1/1/2018 forward do not use code 8480 (mucinous adenocarcinoma) for in‐ situ adenocarcinoma, mucinous or invasive mucinous adenocarcinoma. 1 Status ICD‐O‐3 Term Reportable Comments Morphology Y/N Code Behavior 8250/2 Adenocarcinoma in situ, non‐mucinous (C34. _) Y code/term New Term 9110/3 Adenocarcinoma of rete ovarii (C56.9) Y New 8163/3 Adenocarcinoma, pancreatobiliary‐type (C24.1) Y Cases diagnosed prior to code/term 1/1/2018 use code 8255/3 Behavior 8983/3 Adenomyoepithelioma with carcinoma (C50. _) Y Code/term New Term 8620/3 Adult granulosa cell tumor (C56.9 ONLY) N Not reportable for 2018 cases New Term 9401/3 Anaplastic astrocytoma, IDH‐mutant (C71. -
Evidenzbericht: S3-Leitlinie „Adulte Weichgewebesarkome“
Institut für Forschung in der Operativen Medizin (IFOM) Evidenzbericht: S3-Leitlinie „Adulte Weichgewebesarkome“ IFOM - Institut für Forschung in der Operativen Medizin (Universität Witten/Herdecke) Jessica Breuing, Tim Mathes, Katharina Doni, Tanja Rombey, Barbara Prediger, Dawid Pieper Datum: 03.07.2020 Kontakt: Jessica Breuing IFOM - Institut für Forschung in der Operativen Medizin Univ.-Prof. Dr. Rolf Lefering Fakultät für Gesundheit, Department für Humanmedizin Universität Witten/Herdecke Ostmerheimer Str. 200, Haus 38 51109 Köln Tel.: 0221 98957-41 Fax: 0221 98957-30 Dr. Tim Mathes IFOM - Institut für Forschung in der Operativen Medizin Univ.-Prof. Dr. Rolf Lefering Fakultät für Gesundheit, Department für Humanmedizin Universität Witten/Herdecke Ostmerheimer Str. 200, Haus 38 51109 Köln Tel.: 0221 98957-43 Fax: 0221 98957-30 Inhalt 1. Literaturrecherche ........................................................................................................................ 5 1.1. Einschlusskriterien Systemtherapie ....................................................................................... 5 1.1.1. Neoadjuvante Systemtherapie (+ GIST) ........................................................................ 5 1.1.2. Adjuvante Systemtherapie (+ GIST) ............................................................................... 5 1.1.3. Therapie der metastasierten Erkrankung (+ GIST) ...................................................... 6 1.2. Einschlusskriterien Chirurgie .................................................................................................. -
TUMOR and STAGING DATA Primary Site Code
SECTION IV - TUMOR and STAGING DATA Primary Site Code NAACCR Version 11.1 field "Primary Site", Item 400, columns 291-294 It is unclear how the 2007 MP/H rules may alter rules for assigning the best Primary Site Formatted: Left Code to each primary. Continue to use the following rules until new rules are issued. Enter the code for the site of origin from the Topography section of ICD-O-3. [Note that ICD-O-2 code C14.1, laryngopharynx, should not be used for diagnoses made on or after January 1, 1995. "Laryngopharynx" became an equivalent term under C13.9 (hypopharynx, NOS) as of this diagnosis date. Code C14.1 is not an ICD-O-3 code.] Enter the site code that matches the narrative primary site indicated in the medical record, or the site code most appropriate for the case. Site codes are found in ICD-O-3's Numerical Lists - Topography section (pages 45-65) and in its Alphabetic Index (pages 105-218). In ICD-O-3 primary site codes consist of the letter "C" followed by two digits, a decimal point, and a third digit. "C" should be entered but the decimal point should not be entered. Example: The primary site is "cardia of stomach". Look this up in the Alphabetic Index of ICD-O-3 under "stomach" or "cardia", and the corresponding code "C16.0" is found. Enter C160. Most sites include a third digit of "8" to be used for single tumors that overlap the boundaries of two or more anatomically contiguous subsites and whose exact point of origin cannot be determined, unless the combination of sites is specifically indexed elsewhere.