1 Effects of temperature on amoebic gill disease 2 development: does it play a role? 3 Ottavia Benedicenti *a,b, Tom G. Pottinger c, Catherine Collins b,d, 4 Christopher J. Secombes *a 5 6 a Scottish Fish Immunology Research Centre, Institute of Biological and Environmental 7 Sciences, University of Aberdeen, Tillydrone Avenue, Aberdeen AB24 2TZ, UK 8 b Marine Scotland Science Marine Laboratory, 375 Victoria Rd, Aberdeen AB11 9DB, UK 9 c Centre for Ecology & Hydrology, Lancaster Environment Centre, Library Avenue, Bailrigg, 10 Lancaster LA1 4AP, UK 11 d Museum National d’Histoire Naturelle (MNHN), Unité Mixte de Recherche UMR Biologie 12 des Organismes et Ecosystèmes Aquatiques (BOREA), 7 rue Cuvier 75231 Paris Cedex 05 13 14 *Corresponding authors: 15 Ottavia Benedicenti 16 Centro de Investigación en Sanidad Animal, 17 Instituto Nacional De Investigaciones Agrarias, 18 Carretera Algete-El Casar de Talamanca, Km. 8,1, 19 28130 Valdeolmos, Madrid, Spain 20 E-mail:
[email protected] 21 Tel: +34 916202300 22 23 Chris Secombes 24 Scottish Fish Immunology Research Centre, 25 Institute of Biological and Environmental Sciences, 26 University of Aberdeen, 27 Tillydrone Avenue, 28 Aberdeen AB24 2TZ, UK 29 E-mail:
[email protected] 30 1 31 Acknowledgements 32 This work was supported by a PhD studentship from the Marine Collaboration Research 33 Forum (MarCRF), which is a collaboration between the University of Aberdeen and Marine 34 Scotland Science (MSS), Marine Laboratory, UK, and by Scottish Government project grant 35 AQ0080. Thanks go to Dr. Una McCarthy for invaluable advice regarding the in vivo 36 experiment, to Dr.