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Authors: Pallavi Subhraveti Peter D Karp Ingrid Keseler An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane are shown on the membrane. Anamika Kothari Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000980815Cyc: Corynebacterium camporealensis DSM 44610 Cellular Overview Connections between pathways are omitted for legibility. Ron Caspi phosphate phosphate (S)-lactate phosphate ammonium predicted ABC RS04760 RS02955 RS06425 RS10630 transporter of phosphate

phosphate (S)-lactate phosphate ammonium phosphate

Amine and Tetrapyrrole Amino Acid Degradation glutaminyl-tRNA gln Aminoacyl-tRNA Charging Polyamine a ring-opened 7- a DNA containing (1S,2R)-1- a [ThiI - biosynthesis via transamidation Biosynthesis an apo [peptidyl- all-trans- an L-asparaginyl- an L-cysteinyl- Polyprenyl Biosynthesis siroheme biosynthesis TCA cycle TCA cycle IV (2-oxoglutarate decarboxylase) L-valine degradation I L- methylguanine an apurinic/ ser C-(indol-3- carrier ]- cys a [glutamine- L-isoleucine degradation I L-leucine degradation I L- carrier protein] ATP retinyl palmitate [tRNA Asn ] [tRNA Cys ] dGDP spermidine degradation I in DNA apyrimidinic site yl)glycerol L- synthetase]- glu degradation I L- class 1b di-trans,poly-cis biosynthesis I 3-phosphate uroporphyrinogen-III (S)-malate val carboxylesterase/ ribonucleoside- -undecaprenyl ile leu 4'-phosphopantetheinyl cysteine uroporphyrin-III thr asn bifunctional DNA- III: family aminoacyl-tRNA aminoacyl-tRNA diphosphate phosphate biosynthesis SAM branched-chain : desulfurase: bifunctional methyltransferase: branched-chain asparaginase: formamidopyrimidine UL81_RS00910 protein: : hydrolase: reductase: amino acid threonine UL81_RS07065 synthase: UL81_RS06110 glutamine-synthetase (2E,6E)-farnesyl UL81_RS01295 amino acid branched-chain UL81_RS07655 glycosylase/ bifunctional DNA- UL81_RS08445 UL81_RS04030 UL81_RS04030 UL81_RS09125 IPP aminotransferase: dehydratase: holo-ACP UL81_RS11265 adenylyltransferase/ an L-glutamyl- diphosphate uroporphyrinogen-III aminotransferase: amino acid DNA-(apurinic or formamidopyrimidine cysteine aminoacyl-tRNA aminoacyl-tRNA UL81_RS09135 malate dehydrogenase: UL81_RS07895 (2Z)-2-aminobut-UL81_RS07575 asp synthase: UL81_RS11270 deadenyltransferase: carboxylesterase/ gln [tRNA Gln ] C-methyltransferase: UL81_RS07895 aminotransferase: 4-methyl-2- apyrimidinic site) glycosylase/ desulfurase: hydrolase: hydrolase: UL81_RS08745 2-enoate UL81_RS09000 tryptophan UL81_RS08105 lipase family GDP isoprenyl geranylgeranyl UL81_RS03060 3-methyl-2- UL81_RS07895 oxopentanoate : UL81_RS07400 DNA-(apurinic or UL81_RS04995 UL81_RS04065 UL81_RS04065 Asp-tRNA(Asn) putrescine dAdoMet synthase protein: glycerol transferase: diphosphate precorrin-1 class II fumarate oxobutanoate (S)-3-methyl-2- apyrimidinic site) /Glu-tRNA(Gln) subunit beta: a [glutamine UL81_RS04560 phosphate UL81_RS08340 biosynthesis fumarate hydratase: aspA oxaloacetate oxopentanoate a 5'-phospho- a 3'-phospho- 2,6-diamino-4- a holo [peptidyl- lyase: UL81_RS07400 a [ThiI sulfur- amidotransferase: uroporphyrin-III 4-oxo-2-pentenal 3',5'-ADP UL81_RS02850 synthetase]-O synthase: (2E,6E)-farnesyl spermidine hydroxy-5-(N-methyl) carrier protein] carrier protein]- tRNA Asn a tRNA Cys UL81_RS05040 isoprenyl [DNA] [DNA] ala 4 asn cys UL81_RS07475 methyltransferase: 2-iminobutanoate L-alanine formamidopyrimidine -(5'-adenylyl) UL81_RS05045 transferase: diphosphate synthase: isovaleryl-CoA D-glyceraldehyde S-sulfanyl- palmitate a retinol UL81_RS07490 geranylgeranyl UL81_RS01295 citrate synthase: degradation IV a 3'-terminal a 5'-phospho- -L-tyrosine UL81_RS05100 UL81_RS04225 UL81_RS05000 isobutanoyl-CoA 3-phosphate trp L-cysteine pyrophosphate uroporphyrinogen-III UL81_RS03500 2-methylbutanoyl- unsaturated sugar [DNA] [+ 7 isozymes] a 5-phosphooxy- synthase: C-methyltransferase: CoA L-glutamyl- di-trans,octa-cis succinate dehydrogenase: 2-methylcitrate synthase: ala ammonium UL81_RS07785 spermidine UL81_RS03060 Gln -undecaprenyl UL81_RS01135 UL81_RS02410 alanine ala RS09340 ala [tRNA ] GGPP 3-methylcrotonyl- 2-oxobutanoate a peptidoglycan a nascent peptidoglycan an N-formyl-L- a carboxy- diphosphate [+ 2 isozymes] CoA dehydrogenase: coenzyme A an apo-[aryl- an N-modified H O a holo [D-alanyl propanoyl-CoA precorrin-2 with (L-alanyl-γ-D- with (L-alanyl-γ-D- methionylaminoacyl- adenylated- cys 2 D-ala Asp-tRNA(Asn) undecaprenyl- succinate citrate methylacrylyl-CoA (E)-2- 2-ketobutyrate UL81_RS08880 carrier protein] aminoacyl-[tRNA] ATP carrier protein] ATP roseoflavin dADP acetyl/propionyl/ glutamyl-meso-2,6- glutamyl-meso-2,6- tRNA [ThiS sulfur- acyl-CoA /Glu-tRNA(Gln) diphosphate methylcrotonoyl- formate-lyase: pyruvate 5'-phosphate aconitate hydratase: acnA enoyl-CoA methylcrotonyl- diaminopimeloyl-D- diaminopimeloyl-D- carrier protein] carboxylase class 1b F0F1 ATP amidotransferase: : succinate-semialdehyde glyoxylate CoA UL81_RS09040 ribonucleoside- H + H + UL81_RS05985 dehydrogenase hydratase: enoyl-CoA CoA carboxylase alanine) tetrapeptide alanine) tetrapeptide 4'-phosphopantetheinyl peptide aminoacyl-tRNA ATPase: cysteine--1-D-myo- subunit beta: synthase UL81_RS05040 subunit alpha: diphosphate di-trans,octa-cis (NADP(+)): gabD2 UL81_RS03965 hydratase: propanoyl-CoA transferase: deformylase: cysteine hydrolase: UL81_RS00980 inosityl 2-amino- UL81_RS10495 bifunctional UL81_RS05045 -undecaprenyl sirohydrochlorin UL81_RS02435 UL81_RS07065 reductase: succinate-semialdehyde (S)-3-hydroxy- UL81_RS03965 L,D- UL81_RS10060 desulfurase: UL81_RS04030 nucleoside 2-deoxy-alpha-D- acyl-CoA riboflavin kinase/ UL81_RS05100 phosphate UL81_RS09125 sirohydrochlorin dehydrogenase: isobutanoyl-CoA (2S,3S)-3- 3-methylglutaconyl- transpeptidase: holo-ACP peptide UL81_RS06110 aminoacyl-tRNA triphosphate glucopyranoside carboxylase: FAD synthetase: his RS04625 his hydroxy-2- CoA UL81_RS07055 UL81_RS09135 chelatase: UL81_RS02650 3-hydroxyisobutyryl- UL81_RS01930 synthase: deformylase: cysteine hydrolase: hydrolase: : UL81_RS02465 an L-glutaminyl- UL81_RS03050 CoA hydrolase: methylbutanoyl- UL81_RS09000 UL81_RS05980 UL81_RS02470 ADP predicted Gln succinate semialdehyde cis-aconitate propanoyl UL81_RS06270 desulfurase: UL81_RS04065 UL81_RS04145 [tRNA ] CoA roseoflavin ABC UL81_RS03915 phosphate a nascent peptidoglycan UL81_RS04995 UL81_RS02480 his RS04635 his siroheme aconitate hydratase: acnA 3-hydroxy-2- (S)-methylmalonyl- adenine met transporter met multifunctional oxoglutarate (S)-3-hydroxy- with L,D cross links D-ala a holo-[aryl- + a D-alanyl- methylbutyryl-CoA acetate kinase: 3',5'-ADP a L-methionylaminoacyl- an uncharged phosphate H CoA dinucleotide of L- tRNA charging decarboxylase/oxoglutarate isobutanoate HMG-CoA (meso-diaminopimelate carrier protein] formate an N-modified ADP [D-alanyl dehydrogenase: UL81_RS10120 tRNA a thiocarboxy- amino acid tRNA dehydrogenase thiamine 3-hydroxyisobutyrate containing) ala carrier protein] a reduced UL81_RS03990 AMP [ThiS-Protein] pyrophosphate-binding dehydrogenase: propanoate H O c-type lys RS05115 lys phe a tRNA Phe 2-methylacetoacetyl- 2 elongator subunit/dihydrolipoyllysine- UL81_RS04010 cytochrome Trp Met Arg Tyr Ala asp His Thr Pro Ile Gly Val Cys Lys ser Leu CoA RS09120 an oxidized trp a tRNA Met met initiator tRNA met arg a tRNA tyr a tRNA a tRNA ala tRNA asp his a tRNA thr a tRNA pro a tRNA ile a tRNA gly a tRNA val a tRNA cys a tRNA lys a tRNA ser a tRNA leu a tRNA residue succinyltransferase tRNA (S)-methylmalonate- acetoacetate L-histidine degradation I O c-type subunit: UL81_RS04550 a 7,8-dihydro- 2 asn Asn glu glu gln Gln 2-oxoglutarate D-threo-isocitrate semialdehyde an apo-[LYS2 L- an sn-glycero-3- sn-glycero-3- a [protein] N- (25S)-3- queuosine at a reduced phenylalanine- tRNA a tRNA a tRNA acetyl-CoA C- coenzyme A α-D- an unfolded cytochrome 8-oxoguanine 2-aminoadipyl- phospho-N-(acyl) phospho-N- terminal-formyl- coenzyme A oxocholest- glu position 34 H O c-type lys RS04140 lys -tRNA ligase: tryptophan-- methionine-- methionine-- arginine-- tyrosine-- alanine-- aspartate-- histidine-- threonine-- proline-- isoleucine-- glycine-- valine-- cysteine-- lysine-- -- leucine-- acyltransferase: ATP ATP protein 2 methylmalonate- his in DNA carrier-protein] ethanolamine (arachidonoyl) glucopyranose L-methionine 4-en-26-oate of a tRNA Asp biotin UL81_RS05500 tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: UL81_RS09555 chaperonin RS07865 ancytochrome oxidized semialdehyde histidine ethanolamine 1-phosphate GroEL: UL81_RS05505 UL81_RS02315 UL81_RS03860 UL81_RS03860 UL81_RS04765 UL81_RS05565 UL81_RS06405 UL81_RS06420 UL81_RS06445 UL81_RS06605 UL81_RS07130 UL81_RS07665 UL81_RS08325 UL81_RS08730 UL81_RS09750 UL81_RS09835 UL81_RS10670 UL81_RS11185 [+ 4 isozymes] L-serine degradation ammonia-lyase: O c-type dehydrogenase bifunctional DNA- 4'-phosphopantetheinyl glycerophosphodiester peptide acyl-CoA glutamyl-Q UL81_RS10000 2 NADP-dependent (S)-3-amino-2- UL81_RS04655 sulfate RS05945 sulfatecytochrome an L-methionyl- (CoA acylating): formamidopyrimidine transferase: : -1-phosphate deformylase: synthase: tRNA(Asp) ligase: biotin--[acetyl- pro RS04690 pro an L-phenylalanyl- an L-asparaginyl- an L-glutamyl- an L-glutaminyl- an L-tryptophanyl- an L-methionyl- an L-arginyl- an L-tyrosyl- an L-alanyl- an L-aspartyl- an L-histidyl- an L-threonyl- an L-prolyl- an L-isoleucyl- an L-valyl- an L-cysteinyl- an L-lysyl- an L-seryl- an L-leucyl- isocitrate dehydrogenase: methylpropanoate urocanate glycerophosphodiester chaperonin [elongator a glycyl-[tRNA Gly ] UL81_RS04005 acetyl-CoA propanoyl-CoA glycosylase/ UL81_RS07065 UL81_RS10720 adenylyltransferase: UL81_RS10060 UL81_RS10505 UL81_RS00765 CoA-carboxylase] [tRNA Phe ] [tRNA Asn ] [tRNA Glu ] [tRNA Gln ] [tRNA Trp ] [initiator tRNA Met ] [tRNA Arg ] [tRNA Tyr ] [tRNA Ala ] [tRNA asp ] [tRNA His ] [tRNA Thr ] [tRNA Pro ] [tRNA Ile ] [tRNA Val ] [tRNA Cys ] [tRNA Lys ] [tRNA ser ] [tRNA Leu ] UL81_RS02265 ser phosphodiesterase: GroEL: tRNA Met ] urocanate holo-ACP UL81_RS03350 ligase: L-serine DNA-(apurinic or glycerophosphodiester UL81_RS03830 peptide acyl-CoA UL81_RS02090 hydratase: synthase: UL81_RS02515 sulfite RS05360 sulfite hydrogencarbonate ammonia-lyase: apyrimidinic site) phosphodiesterase: glycerophosphodiester glucose-1-phosphate deformylase: synthetase: glutamyl- a protein UL81_RS04665 UL81_RS09000 UL81_RS00670 lyase: UL81_RS07400 UL81_RS03830 phosphodiesterase: adenylyltransferase: UL81_RS06270 UL81_RS01075 queuosine at Fermentation 4-imidazolone- UL81_RS10720 UL81_RS04515 position 34 biotinyl-5'- L-glutamate L-serine a holo-[LYS2 L- 5-propanoate (25S)-3- of a tRNA Asp adenylate degradation II ammonia-lyase: a 5'-phospho- a 3'-phospho- 7,8-dihydro- 3',5'-ADP 2-aminoadipyl- an N- an N-terminal L- sulfite RS03055 sulfite Glycolysis pyruvate 4-oxo-2-pentenal sn-glycerol formate oxocholest-4- 2-aminoprop-UL81_RS06440 imidazolonepropionase: [DNA] [DNA] 8-oxoguanine carrier-protein] 3-phosphate acylethanolamine sn-glycerol ADP-α-D-glucose methionyl-[protein] fermentation L-glutamine UL81_RS04670 anandamide en-26-oyl-CoA [2Fe-2S] iron-sulfur , Carrier, and Vitamin Biosynthesis glycolysis I (from glucose 6-phosphate) degradation I glu 2-enoate 3-phosphate superpathway of tetrahydrofolate biosynthesis mycothiol biosynthesis molybdenum cofactor biosynthesis NAD biosynthesis from 2-amino- adeninyl adenosylcobamide to (S)-lactate acetate acetate cluster biosynthesis aspartate N-formimino- 3-carboxymuconate semialdehyde biosynthesis from pyruvate transaminase: RS03520 D-glucopyranose Secondary Metabolite Biosynthesis D-glucopyranose gln L-glutamate 2-amino-3- adenosylcobinamide-GDP L-lactate UL81_RS10365 3 a peptide with a metal a metal L- 6-phosphate 6-phosphate L-glutamine a purine base AsbD acyl- an N -methyladenine N-acetyl- GTP ATP cys carboxymuconate- dehydrogenase: imidazole glycerol asp coenzyme A glu a (6S)-5- (-)-methyl jasmonate a RNA-DNA hybrid an N-terminal met ser cation cation 2-iminopropanoate degradation II formimidoylglutamase: lesion in DNA carrier protein in DNA L-citrulline a sugar RS09160 a sugar inositol-3- 6-semialdehyde adenine methylerythritol phosphate pathway I glucose-6- UL81_RS10725 phosphate formyltetrahydrofolate L-alanine cysteine autoinducer AI-2 biosynthesis I UL81_RS04630 bifunctional L-serine phosphate molybdopterin- cysteine nicotinate-nucleotide-- phosphate (S)-lactate synthase: class II fumarate desulfurase: GTP gln bifunctional DNA- DNA-3- carboxylesterase/ bifunctional glutamate N- ammonia-lyase: synthase: synthase desulfurase: dimethylbenzimidazole D-glyceraldehyde : UL81_RS07475 hydratase: aspA 4'-phosphopantetheinyl acetylornithine UL81_RS04995 cyclohydrolase quinolinate pyruvate glutamate glu formamidopyrimidine bifunctional methyladenine lipase family protein: RNase H/acid aminopeptidase acetyltransferase/ UL81_RS00670 UL81_RS11090 adenylyltransferase: UL81_RS04995 phosphoribosyltransferase: 3-phosphate UL81_RS03650 UL81_RS07490 aspartate transferase: deacetylase: a sugar RS02500 a sugar cysteine I FolE: SAM synthase glycosylase/ folylpolyglutamate glycosylase I: UL81_RS08445 phosphatase: N: UL81_RS08820 amino-acid L-serine UL81_RS00630 cysteine nicotinate- UL81_RS07890 [+ 7 isozymes] ammonia-lyase: UL81_RS07065 UL81_RS00350 desulfurase: UL81_RS09900 Ins(3)P UDP-N-acetyl- a carboxy- pyruvate subunit DNA-(apurinic or synthase/ UL81_RS03270 UL81_RS08135 aminopeptidase acetyltransferase ammonia-lyase: 7,8- desulfurase: GTP nucleotide adenine ribotide 1-deoxy-D- F6P glu UL81_RS05955 holo-ACP carboxylesterase/ UL81_RS06110 α-D-glucosamine adenylated beta: gltD apyrimidinic site) dihydrofolate N: UL81_RS11350 ArgJ: UL81_RS06440 dihydroneopterin UL81_RS06110 diphosphorylase phosphate xylulose-5- synthase: DNA-3- lipase family protein: HII: [small subunit of glu lyase: UL81_RS07400 synthase: UL81_RS05515 pyruvate a sugar RS02875 a sugar an S-sulfanyl-[L- 3'-triphosphate an [L-cysteine GTP 3',8- (carboxylating): phosphate SAH fumarate UL81_RS09000 methyladenine UL81_RS04560 UL81_RS07285 acetate D-inositol-3-phosphate molybdopterin fructose- UL81_RS08725 N-acetyl-L- L-citrulline cysteine desulfurase] desulfurase]-S- cyclase MoaA: UL81_RS04130 synthase: glycosylase I: glycosyltransferase: synthase] bisphosphatase 6-phosphofructokinase: ala a peptide methionine sulfanyl-L-cysteine UL81_RS04860 UL81_RS06695 a 5'-phospho- a 3'-phospho- a modified UL81_RS03800 UL81_RS01230 (8S)-3',8-cyclo-7,8- NaMN class II: UL81_RS05085 4-oxo-2-pentenal a holo-[AsbD acyl- a (6S)-5- (-)-jasmonate MeOH DNA a nucleoside 5'- a sugar RS00305 a sugar 7,8- Coα-[α-(adenin-9-yl)]- [DNA] [DNA] nucleobase 3',5'-ADP 2-carboxy-1,4- molybdopterin dihydroguanosine UL81_RS04300 carrier protein] formyltetrahydrofolate monophosphate dihydroneopterin 1-O-(2-acetamido- Coβ-adenosylcobamide 1-deoxy-D-xylulose Amine and Polyamine Degradation an S-sulfanyl-[cysteine flavin biosynthesis I ( and plants) naphthoquinol biosynthesis synthase 5'-triphosphate nicotinate-nucleotide 3-methyladenine an apurinic site 3'-phosphate 2-deoxy-α-D- 5'-phosphate 5-phosphate S-ribosyl-L-homocysteine β-D-fructose 1,6- desulfurase]-[disordered- : cyclic pyranopterin adenylyltransferase: within DNA glucopyranosyl)-1D-myo 1-deoxy-D-xylulose- bisphosphate Detoxification superpathway of 4- Peptide RS08485 Peptide form scaffold chorismate UL81_RS00630 monophosphate UL81_RS08615 DHAP Pentose Phosphate Pathways 4-aminobutanoate -inositol 3-phosphate isochorismate synthase MoaC: 5-phosphate S-ribosylhomocysteine aminobutanoate degradation protein] complex GTP nicotinate adenine class II fructose- degradation III adenine 2503 2-deoxy-D- a mycothiol a peptide with [cysteine desulfurase]-S- synthase: a thiocarboxylated α α reductoisomerase: lyase: UL81_RS01195 reactive species degradation [EntB aryl- D-erythro-7,8- UL81_RS04850 dinucleotide Co -[ -(adenin-7-yl)]- bisphosphate arsenate coenzyme A glycerophosphoglycerol acibenzolar-S-methyl methylsalicylate an N-terminal ser sec sulfanylcysteine:[acceptor UL81_RS05250 [small subunit of cyclic UL81_RS07200 pentose phosphate pathway 4-aminobutanoate in 23S rRNA carrier protein] 5-phosphate S-conjugate a tRNA dITP dihydroneopterin chorismate Coβ-adenosylcobamide triose-phosphate aldolase: detoxification V 4-aminobutanoate L-proline Peptide RS08760 Peptide protein]-cysteine bifunctional isochorismate molybdopterin pyranopterin AI-2 4-aminobutyrate- non-canonical dihydroneopterin 1-(2-acetamido- MEP isomerase: UL81_RS10170 D-glucopyranose superoxide 4-aminobutyrate- sulfurtransferase: aminodeoxychorismate 3,4-dihydroxy- α synthase] phosphate -2-oxoglutarate 23S rRNA glycerophosphodiester carboxylesterase/ carboxylesterase/ mycothiol purine NTP aldolase: 2-deoxy- -D- UL81_RS06195 6-phosphate arsenate -2-oxoglutarate 4'-phosphopantetheinyl deoxyribose- proline UL81_RS04995 synthase: UL81_RS01640 2-butanone- 2-succinyl-5- transaminase: (adenine(2503)-C(2) phosphodiesterase: lipase family protein: lipase family protein: conjugate serine-- pyrophosphatase, glucopyranosyl)- NAD + 2-C-methyl-D- superoxide dismutase: glyceraldehyde- transaminase: transferase: phosphate 2+ 2+ a [cysteine desulfurase]- UL81_RS09890 4-phosphate enolpyruvyl- molybdopterin glucose-6- UL81_RS02685 )-methyltransferase amidase Mca: iminopeptidase: tRNA ligase: Co Co 1D-myo-inositol UL81_RS10740 3-phosphate succinate UL81_RS03830 aldolase: UL81_RS08445 UL81_RS08445 RdgB/HAM1 family: 2+ RS05785 2+ S-sulfanyl-[disordered- 6-(hydroxymethyl) 4-amino-4- synthase/GTP 6-hydroxy-3- 5-methylbenzimidazolyl erythritol 4-phosphate D-glyceraldehyde phosphate succinateUL81_RS02685 UL81_RS07065 UL81_RS09020 UL81_RS10670 Mg Mg N-acetyl-1-D-myo synthase: (2R,4S)-2-methyl-2,4- dehydrogenase: semialdehyde RlmN: glycerophosphodiester UL81_RS08220 carboxylesterase/ carboxylesterase/ UL81_RS04215 UL81_RS09065 form scaffold -7,8-dihydropterin deoxychorismate cyclohydrolase II: cyclohexene- adenosylcobamide biosynthesis cytidylyltransferase: 3-phosphate dehydrogenase: semialdehyde holo-ACP -inositol-2-amino- UL81_RS00635 dihydroxydihydrofuran-3-one hydrogen peroxide UL81_RS04050 UL81_RS07220 phosphodiesterase: lipase family protein: lipase family protein: protein] complex 4-amino-4- UL81_RS06240 1-carboxylic- from adenosylcobinamide-GDP UL81_RS09760 UL81_RS06175 1-arseno-3- succinate- synthase: deoxyribose- dIMP cysteine 2-amino-4-hydroxy-6- 2-deoxy-α-D- 4-(cytidine 5'- glyceraldehyde- NAD-dependent succinate- UL81_RS10720 phosphate UL81_RS04560 UL81_RS04560 an L-seryl- deoxychorismate 2,5-diamino-6- acid synthase: 6-phospho phosphoglycerate semialdehyde UL81_RS09000 2+ 2+ hydroxymethyldihydropteridine 5-methylbenzimidazole 3-phosphate semialdehyde GlcN-Ins a peptide pro sec Mg RS00690 Mg desulfurase: (5-phospho-D- glucopyranoside molybdopterin diphospho)-2-C- succinate- dehydrogenase 2503 aldolase: a mercapturate [tRNA ] diphosphokinase: UL81_RS09885 lyase: UL81_RS01500 nicotinate-nucleotide-- D-glucono- catalase: dehydrogenase: a 2-methyladenine 5'-deoxyadenosine UL81_RS04995 ribosylamino) deacetylase: methyl-D-erythritol dehydrogenase: semialdehyde (NADP(+)): gabD2 met UL81_RS01170 (7,8-dihydropterin- UL81_RS09510 2-succinyl-5- dimethylbenzimidazole (2R,4S)-2-methyl-2,3,3,4- 1,5-lactone UL81_RS00860 UL81_RS02650 in 23S rRNA glycerol sn-glycerol pyrimidin- UL81_RS04415 4-(cytidine 5'- UL81_RS04050 dehydrogenase: 3',5'-ADP a holo-[EntB aryl- acibenzolar MeOH salicylate MeOH cysteine 6-yl)methyl enolpyruvoyl-6- phosphoribosyltransferase: tetrahydroxytetrahydrofuran 6-phosphogluconolactonase: succinate- 3-phosphate 4-aminobenzoate 4(3H)-one diphospho)- H O hydroxyl radical 1-arseno-3- UL81_RS10600 carrier protein] a metal a metal desulfurase: diphosphate GlcN-Ins hydroxy-3-cyclohexene- UL81_RS07890 UL81_RS06185 O 2 semialdehyde succinate D-glyceraldehyde RS02305 2-C-methyl-D- 2 cation cation UL81_RS06110 bifunctional 1-carboxylate molybdopterin 5-methylbenzimidazole 13-DPG phosphoglycerate [+ 2 isozymes] dehydrogenase: acetaldehyde 3-phosphate an S-sulfanyl-[cysteine erythritol kinase: D-gluconate dihydropteroate diaminohydroxyphosphoribosylaminopyrimidine cysteine--1-D-myo- adenine ribotide phosphate UL81_RS02650 desulfurase]-S- UL81_RS03885 6-phosphate synthase: deaminase/5-amino-6-(5-phosphoribosylamino) inosityl 2-amino- dinucleotide phosphoglycerate sulfanyl-[disordered- molybdopterin 2-phospho-4-(cytidine UDP-N-acetyl- a metal a metal UL81_RS09895 uracil reductase RibD: UL81_RS06250 2-deoxy-alpha-D- kinase: phosphogluconate succinate undecaprenyldiphospho- a methylated sn-glycero-3- RS07355 form scaffold 5-amino-6-(5- (1R,6R)-6-hydroxy-2- molybdenumtransferase acyl carrier 5'-diphospho)-2-C- α-D-glucosamine 2-oxoglutarate an unsulfurated a carboxylic ester sulfite GSSH O-phospho- (R)-NADPHX ethylphosphate cation cation glucopyranoside UL81_RS06200 dehydrogenase N-acetylmuramoyl-L- nucleobase phosphoethanolamine cys cys XTP protein] complex dihydropteroate phospho-D- succinylcyclohexa-2,4- MoeA: UL81_RS00645 α α protein activation methyl-D-erythritol myo-inositol γ [sulfur carrier] L-homoserine [cysteine desulfurase]-S- ligase: Co -[ -(5- (NADP(+)- alanyl- -D-glutamyl-meso within DNA bifunctional ADP- alkaline synthase: ribosylamino)uracil diene-1-carboxylate 2-C-methyl-D- biosynthesis non-canonical sulfanylcysteine:[acceptor D-ribulose UL81_RS05980 [+ 2 isozymes] methylbenzimidazolyl)]- an apo acyl- 3-phospho- dependent, -2,6-diaminopimeloyl- dependent (S)- phosphatase: UL81_RS04485 bifunctional 5-phosphate O-succinylbenzoate MoO - Coβ-adenosylcobamide erythritol 2,4- D-glucopyranose D-alanyl-D-alanine alpha- glycerophosphodiester carboxylesterase/ NAD(P)H-hydrate purine NTP a metal a metal protein]-cysteine 2 carrier protein (R)-glycerate decarboxylating) cysteine cystathionine UL81_RS11735 diaminohydroxyphosphoribosylaminopyrimidine synthase: molybdopterin 5'-phosphate holo-ACP cyclodiphosphate 6-phosphate ketoglutarate- phosphodiesterase: lipase family protein: domain- dehydratase/ pyrophosphatase, cation cation sulfurtransferase: bifunctional deacetylmycothiol : UL81_RS05775 desulfurase: gamma-synthase: bifunctional RS08940 7,8- deaminase/5-amino-6-(5-phosphoribosylamino) UL81_RS01455 cofactor folate transformations III (E. coli) synthase: synthase: inositol-3- phosphoglycerate undecaprenyldiphospho- dependent UL81_RS10720 UL81_RS08445 containing NAD(P)H-hydrate RdgB/HAM1 family: UL81_RS04995 3,4-dihydroxy- D-ribulose UL81_RS06110 UL81_RS08865 RNase H/acid ala ala a [cysteine dihydropteroate uracil reductase RibD: UL81_RS06250 mycothiol UL81_RS09000 UL81_RS09755 phosphate mutase: muramoylpentapeptide beta-N- dioxygenase glycerophosphodiester carboxylesterase/ protein: epimerase: UL81_RS09065 desulfurase]-(S- 5-amino-6-(5- 2-butanone- 2-succinylbenzoate synthase: 5-phosphate acetylglucosaminyltransferase: cysteine UL81_RS11110 phosphatase: bifunctional synthase: Coα-[α-(5- 4'-phosphopantetheinyl UL81_RS01235 AlkB: phosphodiesterase: lipase family protein: UL81_RS11130 XMP a metal a metal sulfanyl) -[disordered- phospho-D- 4-phosphate a tetrahydrofolate 2-C-methyl-D-erythritol- UL81_RS11090 Inorganic Nutrient desulfurase: UL81_RS08135 2 folylpolyglutamate UL81_RS09485 selenate reduction UL81_RS07715 UL81_RS03830 UL81_RS04560 cation cation synthase/GTP 2-succinylbenzoate- methylbenzimidazolyl)]- transferase: 2,4-cyclodiphosphate ribulose- ribose-5- assimilatory UL81_RS00435 L-cystathionine (S)-NADPHX RS07395 form scaffold synthase/ ribitylamino)uracil Ins(3)P 2-phospho- UL81_RS04995 ethanol cyclohydrolase II: -CoA ligase: Coβ-adenosylcobamide UL81_RS07065 phosphate 3- phosphate sulfate reduction III protein] complex dihydrofolate mycothiol a holo acyl- flavodoxin- D-glycerate II (meso UDP glutathione thiosulfate ala ala UL81_RS06240 UL81_RS01430 epimerase: isomerase: selenate a nucleobase synthase: carrier protein dependent (E) inositol diaminopimelate containing) formaldehyde succinate ethanolamine sn-glycerol an alcohol a carboxylate 4-(2'-carboxyphenyl) methionine synthase: sulfate sulfate within DNA a sulfurated Zn 2+ RS11040 Zn 2+ 1-deoxy-L- -4-hydroxy-3- monophosphatase: phosphopyruvate UL81_RS06255 UL81_RS08805 3-phosphate ala UL81_RS08725 -4-oxobutyryl-CoA UL81_RS07590 adenylyltransferase: sulfate [sulfur carrier] ARP glycero-tetrulose methylbut-2-enyl- UL81_RS07480 hydratase: a [cysteine desulfurase]- 7,8-dihydrofolate methionine synthase: UL81_RS10330 adenylyltransferase: menaquinol-6 biosynthesis 4-phosphate 1,4-dihydroxy- diphosphate inositol UL81_RS04160 D-xylulose D-ribose 5- [scaffold protein- monoglutamate menaquinol-9 biosynthesis 2-naphthoyl- UL81_RS05015 5-phosphate phosphate sulfate UL81_RS10330 synthase: monophosphatase: two-component alkanesulfonate monooxygenase Zn 2+ RS00130 Zn 2+ 6 37 a mature DNA with adenine:7,8- 38- (2Fe-2S)] complex 6,7-dimethyl-8- CoA synthase: UL81_RS07190 phosphoenol adenylyltransferase sulfate a sulfurated N -dimethylallyladenosine (2-hydroxyphenyl)methyl 1-hydroxy- a uridine UL81_RS06730 methyl (indol-3-yl)acetate glu (S)-4-amino-5- acetyl-CoA H O demethylmenaquinol-6 ribityllumazine peptidoglycan dihydro-8- a tRNA 2 glu ala UL81_RS01445 (E)-4-hydroxy-3- pyruvate transketolase: subunit 2: adenylyltransferase [sulfur carrier] in tRNA 6-oxocyclohex-2-ene-1-carboxylate (n) 40 in tRNA ITP demethylmenaquinone synthase: demethylmenaquinol-9 an alkylsulfonate FMNH (meso-DAP oxoguanine mismatch RluA family oxopentanoate demethylmenaquinone 1,4-dihydroxy-2- methylbut-2-en- myo-inositol UL81_RS06165 5'-UL81_RS10335 subunit 2: 2 non-canonical methyltransferase: UL81_RS06235 containing) pseudouridine 2+ 2+ a [co-chaperone]- a 7,8-dihydrofolate methyltransferase: naphthoyl-CoA 1-yl diphosphate pyruvate kinase: phosphoselenate UL81_RS10335 carboxylesterase/ carboxylesterase/ acetyl-CoA purine NTP Zn RS01415 Zn UL81_RS01515 glycine cleavage system 4-hydroxy-3- D-sedoheptulose D-glyceraldehyde APS synthase: glutamyl-tRNA glutamate-- [scaffold protein- UL81_RS01515 serine UL81_RS07450 tRNA (N6-isopentenyl lipase family protein: lipase family protein: A/G-specific hydrolase: pyrophosphatase, menaquinol-6 6,7-dimethyl-8-(1- protein T: UL81_RS07920 methylbut-2-enyl 7-phosphate 3-phosphate UL81_RS07630 reductase: cysteine ligase: (2Fe-2S)] complex menaquinol-9 a 7,8-dihydrofolate hydroxymethyltransferase: a 5-methyltetrahydrofolate adenosine(37)-C2)- UL81_RS08445 UL81_RS08445 endolytic adenine UL81_RS09450 RdgB/HAM1 family: D-ribityl)lumazine glycine cleavage system diphosphate phosphoadenylyl- methylthiotransferase transglycosylase glycosylase: tRNA UL81_RS01285 UL81_RS10045 SSQ1 chaperone: UL81_RS04240 UL81_RS09065 Zn 2+ RS04385 Zn 2+ riboflavin 1,4-dihydroxy- protein H: UL81_RS07925 reductase: pyruvate transaldolase: sulfate reductase: MiaB: UL81_RS06920 carboxylesterase/ carboxylesterase/ MltG: UL81_RS09795 pseudouridine(38- UL81_RS10275 a tetrahydrofolate 4-hydroxy-3- UL81_RS04325 UL81_RS06170 selenite UL81_RS10340 lipase family protein: lipase family protein: IMP synthase: 2-naphthoate UL81_RS06395 40) synthase TruA: acetate γ a [chaperone-ATP]- IPP UL81_RS04560 UL81_RS04560 an L-glutamyl- -L-glutamyl- UL81_RS06245 thymidylate synthase: methylbut-2-enyl sulfite alkanesulfonate 2-methylsulfanyl-N 6 - UL81_RS01965 [co-chaperone]- D-erythrose flavin reductase: an apurinic site a pseudouridine 38- [tRNA Glu ] D-alanine UL81_RS03620 diphosphate F6P monooxygenase: 5'-deoxyadenosine dimethylallyladenosine 37 met an unsulfurated a mature GlcNAc-1,6- choline RS00455 choline [scaffold protein- riboflavin reductase: 4-phosphate UL81_RS00035 UL81_RS00050 [sulfur carrier] adenine within DNA 40 in tRNA isopentenyl- in tRNA 1-hydroxy-6-oxocyclohex- peptidoglycan anhMurNAc- (2Fe-2S)] complex UL81_RS04325 salicyl alcohol (indol-3-yl)acetate MeOH (n) NAD de novo biosynthesis bifunctional superpathway of pyridoxal 5'-phosphate biosynthesis and salvage diphosphate transketolase: selenodiglutathione 2-ene-1-carboxylate (meso-DAP L-Ala-γ-D-Glu- UL81_RS06165 SSQ1 chaperone I (from aspartate) thiamine diphosphate salvage II riboflavin kinase/ Delta-isomerase: containing) DAP-D-Ala ATPase: FAD synthetase: D-erythrose a (6S)-5-formyltetrahydrofolate UL81_RS08450 D-glyceraldehyde 4-phosphate UL81_RS10275 4-amino-2-methyl-5- UL81_RS07055 3-phosphate asp 5-formyltetrahydrofolate a nascent peptidoglycan sn-glycerol a CDP- a double-stranded long chain pyrimidinemethanol methylenetetrahydrofolate urea cycle γ hydrogen cyanide a sulfurated glycerophosphoserine oxaloacetate a cytidine 34 lys urea-1-carboxylate 3',5'-ADP FMN cyclo-ligase: UL81_RS03775 glutathioselenol gly with (L-alanyl- -D-glutamyl- 3-phosphate diacylglycerol ITP oligonucleotide polyphosphate a [chaperone- dehydrogenase: DMAPP [sulfur carrier] in tRNA Ile2 an [2Fe-2S] bifunctional an aldehyde FMN meso-2,6-diaminopimeloyl- oligoribonuclease: polyphosphate 3'(2'),5'- ADP]-[disordered- 4-phospho- UL81_RS02220 cluster protein 2-iminosuccinate hydroxymethylpyrimidine bifunctional a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate thiosulfate D-alanine) tetrapeptide UL81_RS08945 kinase 2: bisphosphate form scaffold D-erythronate arg rhodanese glycerophosphodiester allophanate kinase/ riboflavin kinase/ disproportionation L,D- CDP-diacylglycerol-- bifunctional tRNA(Ile)-lysidine UL81_RS09990 protein] complex quinolinate bifunctional domain- phosphodiesterase: phosphoenolpyruvate hydrolase: phosphomethylpyrimidine FAD synthetase: IV (rhodanese) transpeptidase: glycerol-3-phosphate 3- oligoribonuclease/ synthetase: polyphosphate CysQ: non-chaperonin synthase NadA: methylenetetrahydrofolate containing UL81_RS10720 carboxykinase (GTP) UL81_RS02580 kinase: UL81_RS05795 UL81_RS07055 hydrogen selenide argininosuccinate UL81_RS01930 phosphatidyltransferase: PAP phosphatase UL81_RS09915 kinase 2: UL81_RS03625 molecular UL81_RS04135 dehydrogenase/ thiosulfate protein: glycerophosphodiester : UL81_RS10460 chaperone (3R)-3-hydroxy-2-oxo- phosphate lyase: ammonium UL81_RS06990 NrnA: UL81_RS04055 HMP-P FAD coenzyme A biosynthesis I (prokaryotic) methenyltetrahydrofolate acquisition UL81_RS11110 phosphodiesterase: UL81_RS07080 long chain AMP ATPase: quinolinate 4 phosphooxybutanoate D-glyceraldehyde UL81_RS05545 a nascent peptidoglycan a lysidine 34 ammonium CO pyruvate cyclohydrolase: Macromolecule Modification rhodanese domain- 1-(3-sn- UL81_RS03830 a nucleoside 5'- 2 polyphosphate UL81_RS10275 bifunctional 5-(2-hydroxyethyl) phosphoserine 3-phosphate a phosphate carbamoyl- with (L-alanyl-γ-D-glutamyl- D-ala CMP in tRNA Ile2 nicotinate- (R)-4'- UL81_RS02220 containing protein: L-arginino- phosphate phosphatidyl) phosphoenolpyruvate monophosphate an [Fe-S cluster hydroxymethylpyrimidine -4-methylthiazole transaminase: monoester L-ornithine meso-2,6-diaminopimeloyl- thiocyanate an unsulfurated IDP nucleotide phosphopantothenatebifunctional tRNA processing UL81_RS11110 bifunctional succinate synthase: carB -sn-glycerol biosynthesis kinase/ hydroxyethylthiazole UL81_RS03495 1-deoxy-D- an N 10 -formyltetrahydrofolate glycine) tetrapeptide [sulfur carrier] sn-glycerol diphosphorylase phosphopantothenoylcysteine Aromatic Compound Biosynthesis RNase H/acid UL81_RS06315 3-phosphate ser chaperone]-ATP phosphomethylpyrimidine kinase: UL81_RS05805 4-phosphooxy- xylulose-5- 3-phosphate (carboxylating): phosphate decarboxylase/ a polycistronic phosphatase: kinase: UL81_RS05795 4-methyl-5-(2- L-threonine thiocyanate sulfite carbamoyl UL81_RS04130 synthase: pyridoxine phosphopantothenate--cysteine chorismate biosynthesis I tRNA precursor UL81_RS08135 phosphooxyethyl) dipicolinate biosynthesis ornithine phosphate HMP-PP UL81_RS06695 ligase CoaBC: UL81_RS06285 phosphate argininosuccinate α thiazole pyridoxamine (R)-4'- carbamoyltransferase: a protein with a [disulfide- 3-phospho- an NDP- - phosphoenol an L-aspartyl- (2R,3S)-2- (3R,5S)-3- NaMN phosphopantothenate biosynthesis I D-erythrose synthase: all-trans-retinyl palmitate DHAP thiamine diphosphate pyridoxal phosphopantothenoyl- 2-methyladeninyl ribonuclease E: ribonuclease E: reduced L- bond carrier dGTP (R)-glycerate D-glucose pyruvate a tRNA precursor Asn methylisocitrate hydroxy-1- 3-amino-1- 1-deoxy-D- 4-phosphate UL81_RS05530 dGDP [tRNA ] biosynthesis III nicotinate-nucleotide thiamine kinase PdxY: pyridoxal L-cysteine adenosylcobamide biosynthesis 3-deoxy-7- asp UL81_RS08690 UL81_RS08690 UL81_RS05540 cysteine residues protein] carrying Asp-tRNA(Asn) NAD(P)- pyrroline-5- hydroxyacetone xylulose 5- kinase PdxY: bifunctional from adenosylcobinamide-GDP phosphoheptulonate phosphonoacetate L-citrulline a disulfide bond dependent carboxylatepyrroline-5- (Staphylococcus) adenylyltransferase: phosphate UL81_RS08375 3-methyl-2-oxobutanoate aspartate kinase: glucosyl-3- carboxylesterase/ /Glu-tRNA(Gln) methylisocitrate 2-(2-carboxy-4- 1-phosphate phosphate UL81_RS08375 phosphopantothenoylcysteine synthase class II: a tRNA precursor a tRNA precursor with degradation glycerol-3- carboxylate UL81_RS08615 synthase: pyridoxal pyridoxal 2-methyladenine UL81_RS00840 phosphoglycerate lipase family protein: ribonuclease D: amidotransferase: lyase: methylthiazol-5- heme a biosynthesis decarboxylase/ 3-methyl-2-oxobutanoate UL81_RS07805 with a 5' extension a 5' extension and DSBA deoxyguanosinetriphosphate phosphate reductase: HMP-PP nicotinate adenine UL81_RS05800 kinase PdxY: pyridoxal nicotinate-nucleotide-- 3-deoxy- L-aspartyl- synthase: UL81_RS04560 pyruvate kinase: UL81_RS06690 UL81_RS05040 UL81_RS02405 yl)ethyl phosphate phosphopantothenate--cysteine hydroxymethyltransferase: and a long 3' trailer a short 3' extension phosphonoacetate : triphosphohydrolase: dehydrogenase: UL81_RS01265 dinucleotide UL81_RS08380 kinase PdxY: dimethylbenzimidazole D-arabino- 4-phosphate UL81_RS04490 UL81_RS07450 UL81_RS05045 pyridoxal ligase CoaBC: UL81_RS06285 UL81_RS08735 ribonuclease D: ribonuclease phosphonoacetate UL81_RS08815 UL81_RS08300 carboxylesterase/ UL81_RS05315 Hyp NAD+ thiamine protoheme UL81_RS08380 phosphoribosyltransferase: heptulosonate UL81_RS05100 thiamine thiamine diphosphate kinase PdxY: aspartate- UL81_RS06690ribonuclease PH: P protein hydrolase: lipase family protein: an L-asparaginyl- sn-glycerol synthetase, phosphate protoheme IX pyridoxine pyridoxamine 2-dehydropantoate UL81_RS07890 7-phosphate ribonuclease D: a [disulfide-bond a nucleoside 5'- pyruvate succinate phosphate biosynthesis I (E. coli) UL81_RS08375 4'-phosphopantetheine semialdehyde UL81_RS09070 component: UL81_RS08065 a protein with 2-O-(α-D- UL81_RS08445 a tRNA [tRNA Asn ] 3-phosphate NH3-dependent: : 5'-phosphate 5'-phosphate 2-methyladenine 3-dehydroquinate UL81_RS06690 acetate carrier protein] a nucleoside pyruvate monophosphate synthase: 2-[(2R,5Z)- pyridoxal dehydrogenase: UL81_RS11400 a disulfide bond triphosphate glucopyranosyl) dGTP UL81_RS09165 UL81_RS06160 pantetheine- ribotide phosphate synthase: with reduced L- 2'-deoxyguanosine diphosphate UL81_RS05800 2-carboxy-4- kinase PdxY: UL81_RS00845 a tRNA precursor with Fatty Acid and Lipid Degradation -3-phospho- ferroheme o phosphate UL81_RS06370 cysteine residues all-trans-retinol palmitate + methylthiazol-5(2H UL81_RS08380 D-glycerate NAD thiamine adenylyltransferase: L-aspartate 4- a short 3' extension thiamine heme A synthase: )-ylidene]ethyl β-alanine 3-dehydroquinate semialdehyde a tRNA precursor oleate β-oxidation diphosphate HMP-PP UL81_RS05355 (R)-pantoate β phosphate UL81_RS06150 phosphate folate polyglutamylation with a 5' extension fatty acid -oxidation I (generic) PLP 3'-dephospho- type II 3- 4-hydroxy- trans,octacis Coα-[α-(2-methyladenin-9- ribonuclease PH: ribonuclease D: 5-methoxy-6- 3-phospho- ADP-α-D-glucose phosphoenol (S)-2- a ribonucleoside an organic a [protein]-L- dCDP CoA pantoate--beta-alanine dehydroquinate tetrahydrodipicolinate oleate a (3Z)-alk-3- NaMN -decaprenyl an all-trans-retinyl ester glu ferroheme i thiamine yl)]-Coβ-adenosylcobamide ribonuclease UL81_RS09070 UL81_RS06690 methylbenzimidazole (R)-glycerate PRPP dADP pyruvate aminobutanoate diphosphate hydroperoxide methionine class 1b a tetrahydrofolate ligase: UL81_RS08740 dehydratase: synthase: enoyl-CoA phosphate thioredoxin- peptide- benzimidazolyl adenosylcobamide phosphate dephospho- 5'-phosphate P protein long-chain-fatty- class 1b ribonucleoside- CoA kinase: UL81_RS06365 UL81_RS07020 ribonucleoside- dependent thiol methionine biosynthesis from thiamine diphosphate heme A synthase: synthase: pantoate--beta-alanine component: ∆ 3 2 diphosphate thiamine (2S,4S)-4- acid--CoA ligase: -cis-∆ -trans- nicotinate-nucleotide-- glucosyl-3- carboxylesterase/ peroxidase: (S)-S-oxide adenosylcobinamide-GDP biosynthesis II (Bacillus) UL81_RS06150 UL81_RS05800 serine formate-- bifunctional UL81_RS05410 ligase: UL81_RS09865 UL81_RS11400 decaprenyl-phosphate glutamate-- diphosphate reductase: 3-dehydroshikimate hydroxy-2,3,4,5- UL81_RS01220 enoyl-CoA dimethylbenzimidazole phosphoglycerate lipase family protein: UL81_RS08990 reductase MsrA: thiamine 2-(2-carboxy-4- hydroxymethyltransferase: tetrahydrofolate folylpolyglutamate phosphoribosyltransferase: pyruvate kinase: cysteine ligase: reductase: UL81_RS09125 benzimidazole coenzyme A Coα-[α-(2-methyladenin-7- tetrahydrodipicolinate NADH repair UL81_RS01225 isomerase: phosphoribosyltransferase: synthase: UL81_RS08445 UL81_RS10735 pyrophosphokinase: methylthiazol-5- hydroxyferroheme i thiamine UL81_RS04240 ligase: synthase/ shikimate UL81_RS10550 UL81_RS07450 UL81_RS10045 UL81_RS09125 thiol peroxidase: a protein-L- UL81_RS09135 nicotinate-nucleotide-- HMP-PP (R)-pantothenate yl)]-Coβ-adenosylcobamide [+ 4 isozymes] UL81_RS03965 UL81_RS07890 UL81_RS04490 carboxylesterase/ UL81_RS05610 yl)ethyl phosphate phosphate UL81_RS05940 dihydrofolate dehydrogenase: a 2'- UL81_RS09135 UL81_RS06455 methionine- dimethylbenzimidazole NADH lipase family protein: CDP phosphoribosyltransferase: a 5,10- synthase: type I pantothenate UL81_RS06390 oleoyl-CoA a (2E)-2- trans,octacis- γ deoxyribonucleoside an alcohol (S)-S-oxide thiamine dipicolinate an uncharged tRNA 5-methoxy-6- 2-O-(α-D- UL81_RS04560 -L-glutamyl-(S)- diphosphate UL81_RS07890 thiamine methylenetetrahydrofolate an N 10 - UL81_RS08725 kinase: UL81_RS04235 enoyl-CoA methylbenzimidazole nicotinate decaprenylphospho- pyruvate 2-aminobutanoate 5'-diphosphate shikimate acyl-CoA glucopyranosyl) β benzimidazole phosphate bifunctional formyltetrahydrofolate menaquinol-11 biosynthesis glutathione ribotide phosphate ADP -D-ribofuranose dATP ferroheme a menaquinol-10 biosynthesis dehydrogenase: enoyl-CoA -3-phospho- ribotide phosphate synthase: thiamine folylpolyglutamate bifunctional biosynthesis (R)-4'-phosphopantothenate long-chain fatty 5-phosphate a tetrahydrofolate shikimate kinase: UL81_RS04645 acyl-CoA hydratase: a 2,3,4- D-glycerate all-trans-retinol a fatty acid UL81_RS05800 diphosphate synthase/ folylpolyglutamate all-trans- a 2,3,4-saturated acid--CoA ligase: undecaprenyl 1,4-dihydroxy- all-trans- UL81_RS06375 (R)-NADHX [+ 3 isozymes] fatty acid UL81_RS08430 dehydrogenase:UL81_RS03965 saturated (3R)-3- dihydrofolate synthase/ cys glu decaprenyl 1,4-dihydroxy- lipoprotein posttranslational diphosphate 2-naphthoate shikimate 3- bifunctional ADP- (2E,9Z)- UL81_RS11230 a 2,3,4- hydroxyacyl-CoA lipoate biosynthesis Coα-[α-(benzimidazolyl) thiamine synthase: dihydrofolate diphosphate 2-naphthoate modification [+ 4 isozymes] a 2,3,4-saturated 3-[(3aS,4S,7aS)-7a-methyl- a 2'- a cis-delta19- phosphate dependent (S)- octadecenoyl-CoA [+ 3 isozymes] saturated (3S)-3- an L-glutamyl- UDP and incorporation I ]-Coβ-adenosylcobamide phosphate menaquinol-7 biosynthesis UL81_RS08725 synthase: fatty acyl CoA 5-methoxybenzimidazole NaMN 1,5-dioxo-octahydro-1H deoxyribonucleoside carbamoyl asp asp O-ureido-L- 37-methoxy-38- [DNA] 1,4-dihydroxy- a [prolipoprotein]- NAD(P)H-hydrate enoyl-CoA hydroxyacyl-CoA coenzyme A ATP [DNA] phosphate [tRNA Gln ] class 1b 5'-phosphate thioredoxin pathway a 5,10- UL81_RS08725 glutathione- glutamate-- 1,4-dihydroxy- 3-phosphoshikimate 1- -inden-4-yl]propanoate a tRNA precursor 5'-triphosphate homoserine methyl-C57:1-[acp] DNA all-trans- 2-naphthoate L-cysteine dehydratase/ hydratase: 3-hydroxyacyl-CoA CTP Asp-tRNA(Asn) cyclopropane- ribonucleoside- an octanoyl-[acp] methylenetetrahydrofolate an N 10 - glutaredoxin cysteine ligase: 2-naphthoate carboxyvinyltransferase: polymerase III: heptaprenyl 1,4-dihydroxy- polyprenyltransferase: NAD(P)H-hydrate UL81_RS03965 dehydrogenase: nicotinate-nucleotide-- /Glu-tRNA(Gln) fatty-acyl- diphosphate lipoate-protein formyltetrahydrofolate redox reactions UL81_RS10045 polyprenyltransferase: UL81_RS03145 prolipoprotein coenzyme A argininosuccinate UL81_RS07545 diphosphate 2-naphthoate an oxidized UL81_RS01395 5-enolpyruvoyl- epimerase: UL81_RS03990 dimethylbenzimidazole acyl-CoA synthase: DNA aspartate amidotransferase: phospholipid reductase: ligase B: thiamine UL81_RS01395 diacylglyceryl (S)-3-hydroxy-(9Z) acetyl-CoA C- CCA tRNA synthase: UL81_RS07595 a [lipoyl-carrier Coα-[α-(benzimidazolyl) thioredoxin glutathione shikimate 3- UL81_RS11130 phosphoribosyltransferase: UL81_RS10505 polymerase III: carbamoyltransferase UL81_RS05040 synthase: UL81_RS09125 UL81_RS07930 diphosphate γ-L-glutamyl- transferase: (S)-NADHX -octadecenoyl-CoA a 2,3,4-saturated acyltransferase:a 2,3,4-saturated nucleotidyltransferase: UL81_RS05540 [+ 5 isozymes] 6 β 1,4-dihydroxy- acyl-CoA synthetase: UL81_RS07545 catalytic subunit: UL81_RS05045 UL81_RS05815 UL81_RS09135 protein] N - ]-Co -adenosylcobamide DMKH2-11 L-cysteine phosphate UL81_RS07455 fatty acyl CoA UL81_RS09555 3-oxoacyl-CoA UL81_RS07890 UL81_RS11320 a nucleoside 5'- 2-naphthoate pyridoxal 5'-phosphate biosynthesis II DMKH2-10 3-hydroxyacyl-CoA UL81_RS01075 UL81_RS07595 UL81_RS06325 UL81_RS05100 a cis-methoxy- octanoyl-L-lysine chorismate a [prolipoprotein]- ATP-dependent dehydrogenase: [+ 4 isozymes] an L-glutaminyl- C59-meroacyl-[acp] monophosphate dUDP polyprenyltransferase: thioredoxin- a reduced demethylmenaquinone demethylmenaquinol- synthase: S-1,2-diacyl-sn- NADH-hydrate [+ 6 isozymes] lipoyl synthase: demethylmenaquinone UL81_RS03990 a tRNA canavaninosuccinate [tRNA Gln ] UL81_RS01395 disulfide glutaredoxin methyltransferase: 8 biosynthesis I UL81_RS06380 glyceryl-L-cysteine dehydratase: 5-methoxybenzimidazole nicotinate 3-[(3aS,4S,7aS)-7a-methyl- UL81_RS07935 demethylmenaquinol- aldehydo-D-ribose D-glyceraldehyde gln methyltransferase: 3-oxo-(9Z)- ribotide phosphate containing a N-carbamoyl- reductase: 5-phosphate 3-phosphate UL81_RS01515 all-trans- UL81_RS11130 1,5-dioxo-octahydro-1H- a [lipoyl-carrier 6 biosynthesis I UL81_RS11360 glutaredoxin: glutathione 1,4-dihydroxy- octaprenyl UL81_RS01515 chorismate signal peptidase octadecenoyl-CoA inden-4-yl]propanoyl-CoA 3' CCA end [DNA] L-aspartate 6 demethylmenaquinol-7 protein]-N -[(R) all-trans- UL81_RS03610 menaquinol-11 2-naphthoate diphosphate II: UL81_RS07635 NADH acetyl-CoA C- acetyl-CoA pyridoxal 5'- menaquinol-10 -dihydrolipoyl]- hexaprenyl 1,4-dihydroxy- demethylmenaquinone a protein with acyltransferase: L-lysine glutathione-peroxide phosphate diphosphate 2-naphthoate methyltransferase: a reduced reduced L- 1,4-dihydroxy- an (S-diacyl-sn- a lipoprotein UL81_RS03955 quinoxaline-2- a 2'- a 1-acyl-2- a dipetide with an N- a cis-delta21-39- redox reactions synthase lyase demethylmenaquinol- 5-hydroxybenzimidazole NaMN L(or D)-O- UL81_RS01515 thioredoxin cysteine residues 2-naphthoate glyceryl)-L-cysteinyl- signal peptide [+ 4 isozymes] aryl-carrier protein carboxyl adenylate DL-allothreonine deoxyribonucleoside [DNA] arachidonoyl- terminal L-aspartate Ins(1)P oxo-40-methyl- a protein mycothiol subunit PdxS: 9 biosynthesis phosphoserine 1,4-dihydroxy- polyprenyltransferase: [apolipoprotein] 5'-triphosphate sn-glycerol inositol C59:1-[acp] GSSG menaquinol-7 oxidation UL81_RS10530 S-adenosyl- thiamine diphosphate apolipoprotein N- cyclopropane- phosphoserine ATP-dependent 2-naphthoate all-trans- UL81_RS01395 (7Z)-hexadecenoyl-CoA 3-phosphate CTP monophosphatase: 1,4-dihydroxy- L-methionine salvage III menaquinol-8 biosynthesis acyltransferase: nicotinate-nucleotide-- fatty-acyl- phosphatase Clp protease polyprenyltransferase: nonaprenyl acyl carrier serine DNA dipeptidase: UL81_RS07480 mycothiol 2-naphthoate biosynthesis UL81_RS05855 acyl-CoA dimethylbenzimidazole phospholipid SerB: proteolytic: clpP UL81_RS01395 diphosphate protein: hydroxymethyltransferase: polymerase III: phosphatidate UL81_RS10005 PLP thiamine demethylmenaquinol-8 demethylmenaquinol-8 an N-acyl-(S-diacyl- a peptide dehydrogenase: phosphoribosyltransferase: inositol synthase: UL81_RS09115 UL81_RS08770 mycothione UL81_RS08185 UL81_RS04240 UL81_RS07545 cytidylyltransferase: 1,4-dihydroxy- met thiamine demethylmenaquinone sn-glyceryl)-L- UL81_RS04645 UL81_RS07890 monophosphatase: UL81_RS05815 serine a peptide reductase: C1 Compound Utilization and Assimilation UL81_RS07595 UL81_RS07230 a cis-keto-C60- demethylmenaquinol-6 mycothione 2-naphthoate methionine pyrophosphokinase: methyltransferase: cysteinyl-[lipoprotein] [+ 3 isozymes] UL81_RS06730 UL81_RS07165 reductase: UL81_RS05610 [+ 6 isozymes] a proteinogenic meroacyl-[acp] polyprenyltransferase: adenosyltransferase: UL81_RS01515 (2E,7Z)- a quinoxaline-2- asp myo-inositol UL81_RS07165 thiamine 5-hydroxybenzimidazole acetaldehyde a CDP-1-acyl- amino acid UL81_RS01395 UL81_RS06280 menaquinol-8 hexadecenoyl-CoA formate assimilation into 5,10- nicotinate AMP carboxyl-[aryl- gly SAM diphosphate methylenetetrahydrofolate formaldehyde ribotide phosphate carrier protein] 2-arachidonoyl- enoyl-CoA formaldehyde glutathione protein Pupylation oxidation III [DNA] glycerol hydratase: oxidation V mycothione demethylmenaquinol-9 Biosynthesis and dePupylation formate (mycothiol-dependent) UL81_RS03965 (bacillithiol-dependent) formaldehyde a [prokaryotic formate--tetrahydrofolate formaldehyde (S)-3-hydroxy-(7Z) a [TusE sulfur a 5'-half-tRNA 2251 a (1->4)- UDP-N-acetyl-D- ubiquitin-like protein] ligase: UL81_RS05940 34 a nucleoside guanosine dTDP-L-rhamnose -hexadecenoyl-CoA 5,6-dimethylbenzimidazole NaMN a uridine in tRNA O-succinyl-L- α glucosamine biosynthesis I trehalose biosynthesis I 10 carrier protein]-S cys a ribonucleic acid a 3'-half-tRNA molecule with in 23S rRNA Ins(2)P -D-glucan a C-terminal L-glutaminePup deamidase: an N -formyltetrahydrofolate homoserine triphosphate IMP UDP-α-D-galactofuranose 3-hydroxyacyl-CoA S-(hydroxymethyl) -sulfanylcysteine molecule with a 2',3'-cyclic 23S rRNA inositol 1,4-alpha-glucan Fatty Acid and Lipid Biosynthesis D-glucopyranose UL81_RS05915 S-(hydroxymethyl) proteasome α-D- D-glucopyranose biosynthesis a [prokaryotic dehydrogenase: bifunctional mycothiol a 5'-OH end phosphate end (guanosine(2251) monophosphatase: bifunctional branching Metabolic Regulator Biosynthesis 6-phosphate UDP-α-D-glucose bacillithiol nicotinate-nucleotide-- ATPase: glucose-6- glucopyranose 6-phosphate ubiquitin-like protein] UL81_RS03990 methylenetetrahydrofolate S-(hydroxymethyl) tRNA 2- cystathionine DNA-directed -2'-O)- UL81_RS07480 metallophosphatase/ protein GlgB: α C-terminal L-glutamate S-(hydroxymethyl) dimethylbenzimidazole 5'-nucleotidase: UL81_RS04960 UL81_RS05920 phosphatidylinositol mannoside biosynthesis stearate biosynthesis acyl-CoA hydrolysis phosphate 1-phosphateglucose-1-phosphate UDP- -D-glucose 3-oxo-(7Z)- dehydrogenase/ mycothiol thiouridine(34) gamma-synthase: RNA polymerase: methyltransferase inositol a (1,6)-α-D- fatty acid elongation -- saturated mannosylglucosylglycerate trehalose-6- Pup--protein mycothiol phosphoribosyltransferase: 2'-5' RNA ligase: RlmB: UL81_RS06505 an unfolded II (bacteria and plants) ppGpp metabolism glucosylglycerate isomerase: thymidylyltransferase: UDP-glucose 4-epimerase hexadecenoyl-CoA methenyltetrahydrofolate dehydrogenase: synthase MnmA: UL81_RS08865 UL81_RS01615 monophosphatase: glucosyl-(1,4) a 1-phosphatidyl- biosynthesis I phosphate ligase: dehydrogenase: UL81_RS07890 UL81_RS02600 UL81_RS09745 protein a 2,3,4-saturated biosynthesis I UL81_RS03650 UL81_RS01095 GalE: UL81_RS06790 acetyl-CoA C- cyclohydrolase: UL81_RS01085 UL81_RS05005 UL81_RS01620 2-O- UL81_RS06730 inosine -α-glucan 1D-myo-inositol F6P dTDP-α-D-glucose synthase: UDP-α-D-galactose UL81_RS05905 UL81_RS01085 fatty acyl CoA an acetoacetyl-[acp] 3-phospho- acyltransferase: UL81_RS02220 [+ 2 isozymes] 2251 a palmitoyl-[acp] acyl-CoA α N6-([prokaryotic S-formylmycothiol methylguanosine myo-inositol phosphatidylinositol 2- UDP- -D-glucose (R)-glycerate pppGpp 3-phospho- dTDP-glucose UL81_RS09680 UDP-galactopyranose UL81_RS03955 S-formylbacillithiol α-ribazole succinate 3-oxo-stearoyl- GDP-α-D-glucose ubiquitin-like protein]- nicotinate a 2-thiouridine 34 a [TusE sulfur carrier L-cystathionine a ligated tRNA in 23S rRNA α-: : (R)-glycerate glutamine-- 4,6-dehydratase: mutase: UL81_RS10635 a 5,10-methenyltetrahydrofolate 5'-phosphate [acp] synthase: α α γ-L-glutamyl)- [+ 4 isozymes] with a 2'-5' linkage UL81_RS06585 UL81_RS08895 GTP pyrophosphokinase: fructose-6- , -trehalose in tRNA protein]-L-cysteine a ribonucleic acid UL81_RS10500 glucosyl-3- UL81_RS01105 UDP-Galf [protein]-L-lysine methylenetetrahydrofolate a 2-O-(α-D-mannosyl) a 3-oxooctadecanoyl- [+ 3 isozymes] UL81_RS07555 glucosyl-3- phosphate GDP-mannose biosynthesis 6-phosphate (5Z)-tetradecenoyl-CoA a 2,3,4-saturated phosphoglycerate guanosine 3'-diphosphate transaminase dTDP-4-dehydro- dehydrogenase: -1-phosphatidyl- [acp] fatty acid synthase: [+ 2 isozymes] 5'-triphosphate 3'- phosphoglycerate 6-deoxy-α-D- trehalose- a 3-oxoacyl-[acp] (isomerizing): acyl-CoA UL81_RS02220 formate 1D-myo-inositol 3-oxoacyl-ACP UL81_RS04490 diphosphatase: synthase: glucopyranose D-glucopyranose phosphatase: formate a mature peptidoglycan (meso DNA combined a [phospholipid]- β-D-glucose UL81_RS04490 UL81_RS02045 a [prokaryotic dehydrogenase: [DNA] a protein with glutathione H O canavaninosuccinate 1-butanesulfonate 6-phosphate UL81_RS09690 a 5,10-methylenetetrahydrofolate -diaminopimelate containing) with exogenous 2 L-ornithine 6-phosphate reductase: UL81_RS06515 dTDP-4- glucose-6- UL81_RS11230 a disulfide bond GTP oleate 2-O-(α-D- D-glucosamine trehalose ubiquitin-like protein] DNA to form a cyclopropane- inositol-3- UL81_RS09550 3-oxoacyl-ACP α dehydrorhamnose phosphate α α thiol RS10390 thiol 2-O-( -D- 6-phosphate , -trehalose biosynthesis IV C-terminal L-glutamate [+ 3 isozymes] fatty-acyl- ornithine phosphate a (3R)-3- reductase: glucopyranosyl) 3,5-epimerase: isomerase: endolytic recombinationalHolliday junction argininosuccinate alkanesulfonate phosphatidylinositol glucopyranosyl) (2E,5Z)- phospholipid cyclodeaminase: synthase: hydroxyoctadecanoyl- UL81_RS09550 -3-phospho- phosphoglucosamine UL81_RS01100 UL81_RS03650 α transglycosylase junction resolvase RuvX: lyase: monooxygenase: mannoside GTP ppGpp -3-phospho- -maltose tetradecenoyl-CoA III: UL81_RS10070 glutaredoxin: GTPase Era: synthase: UL81_RS05555 UL81_RS11090 [acp] CDP-diacylglycerol D-glycerate mutase: UL81_RS02020 dTDP-4-dehydro- F6P maltose alpha-D- MltG: UL81_RS06395 UL81_RS06400 UL81_RS05545 UL81_RS00035 acyltransferase: a (3R)-3- D-glycerate Carboxylate Degradation exodeoxyribonuclease UL81_RS03610 UL81_RS08350 UL81_RS05815 3-hydroxystearoyl- α β 6 37 2+ 2+ biosynthesis I a 2,3,4-saturated -D-glucosamine -L-rhamnose : N -L-threonylcarbamoyladenosine crossover junction pro Ins(3)P Mn RS01405 Mn UL81_RS06590 [acyl-carrier hydroxyacyl-[acyl- mannose-6- enoyl-CoA III: UL81_RS02300 [+ 5 isozymes] a [phospholipid]- a 2,6-di-O-(α- fatty acyl-[acp] 1-phosphate dTDP-4- UL81_RS02485 -modified tRNA biosynthesis a mature peptidoglycan a mature peptidoglycan strand resolution of protein] carrier protein] GTP pyrophosphokinase: phosphate α hydratase: propanoyl-CoA dihydrosterculate DHAP 2-[2-O-(α-D- dehydrorhamnose UDP- -D-glucose α,α-trehalose pyruvate decarboxylation to acetyl CoA with (L-alanyl-γ-D-glutamyl- (non-reducing terminus) a protein with RuvC: UL81_RS06555 L-canavanine fumarate 1-butanal sulfite D-mannosyl)-1- UL81_RS07555 2-O-(α-D- bifunctional UDP-N- UL81_RS03965 a 2'- GSSG recombinational H + dehydratase: NAD(P)- mannopyranosyl) isomerase, class biosynthesis I (3E,5Z)-tetradeca- degradation II meso-2,6-diaminopimeloyl- reduced L- phosphate phosphatidyl- bifunctional (p)ppGpp glucopyranosyl) acetylglucosamine reductase: deoxyribonucleoside [DNA] junction GDP a 2-O-(6-O-acyl- UL81_RS01210 dependent -(1->2)-α-D- GTP pyrophosphokinase: I: UL81_RS03070 ATP 3,5-dienoyl-CoA a [pyruvate D-alanine) tetrapeptide cysteine residues Cu 2+ RS05615 Cu 2+ 1D-myo-inositol synthetase/guanosine- -D-glycerate diphosphorylase/ UL81_RS01100 D-glucopyranose thr (S)-3-hydroxy-(5Z) propanoyl-CoA 5'-monophosphate formation of two α UL81_RS04110 β D-mannopyranose dehydrogenase -D-mannosyl)- a (2E)-octadec- glycerol-3- glucopyranosyl]- nucleoside-diphosphate 3',5'-bis(diphosphate) 3'- glucosamine-1- dTDP- -L- 6-phosphate acyl-CoA pyruvate fermentation intact strands 6-phosphate alpha-D-glucose -tetradecenoyl-CoA acyl-CoA oxidase: E2 protein] N 6 pyruvate phosphatidylinositol 1-phosphatidyl- 2-enoyl-[acp] phosphate a trans-2- 3-phospho- kinase: UL81_RS08700 pyrophosphohydrolase: phosphate N- rhamnose thioesterase: to acetate IV a 2,3,4-saturated phosphate-specific threonylcarbamoyl- 3-hydroxyacyl-CoA UL81_RS09560 -lipoyl-L-lysine dehydrogenase dimannoside 1D-myo-inositol steroyl-[acp] dehydrogenase: enoyl-[acyl- D-glycerate UL81_RS06515 acetyltransferase phosphomannomutase/ UL81_RS08895 UL81_RS05315 fatty acyl-[acp] GDP phosphoglucomutase: phosphoglucomutase: AMP synthase: dehydrogenase: acryloyl-CoA pyruvate (acetyl- a nascent peptidoglycan an [HPr]- phosphoenol RNase III mRNA a [lipoyl-carrier 2+ 2+ acyltransferase: reductase: GlmU: [+ 3 isozymes] a peptide with a an alkylated DNA aci-nitroethane 6 a nucleoside Cd RS00265 Cd sn-glycerol carrier protein] UL81_RS09335 UL81_RS03990 dihydrolipoyl transferring), (meso-DAP containing) L-histidine pyruvate processing protoheme protein]-N -[(R) UL81_RS06590 UL81_RS01210 UL81_RS04090 UL81_RS03030 UL81_RS04885 (3E,5Z)- leader sequence triphosphate GTP 3-phosphate α [+ 2 isozymes] 3-oxo-(5Z)- dehydrogenase: homodimeric type: -dihydrolipoyl]- nucleoside α N-acetyl-α-D- -D-mannose α-D-glucopyranose tetradecadienoate formate C- 2-[2-O-( -D- tetradecenoyl-CoA UL81_RS01125 UL81_RS08175 endolytic L-lysine triphosphate diguanylate a 2-O-(6-O-acyl- a stearoyl-[acp] glucosamine PRPP biosynthesis 1-phosphate 1-phosphate (L-threonylcarbamoyl) acetyltransferase: phosphoenolpyruvate- DNA-3- nitronate dihydrolipoyl α mannopyranosyl) transglycosylase ferrochelatase: hydrolase: cyclase: fluoride RS09345 fluoride -D-mannosyl)-6- α 1-phosphate GDP-mannose adenylate acetyl-CoA C- 3-hydroxypropanoyl- UL81_RS09040 -protein ribonuclease III: signal peptidase methyladenine monooxygenase: dehydrogenase: α cyclopropane long-chain fatty -(1->2)- -D- UTP--glucose- a [pyruvate a [pyruvate UL81_RS06035 UL81_RS04145 O-( -D-mannosyl) type I polyketide a 1-acyl-sn D-ribose 5- pyrophosphorylase: tRNA (adenosine(37)-N6)- acyltransferase: CoA MltG: UL81_RS06395 phosphotransferase: UL81_RS07405 I: UL81_RS07290 glycosylase: UL81_RS04045 UL81_RS01125 UL81_RS02665 fatty acid (CFA) acid activation glucopyranosyl]- bifunctional UDP-N- 1-phosphate dehydrogenase dehydrogenase a [lipoyl-carrier a nucleoside -1-phosphatidyl- synthase: -glycerol 3- phosphate UL81_RS03010 threonylcarbamoyltransferase UL81_RS09555 3-hydroxyisobutyryl- UL81_RS06850 signal peptidase UL81_RS00105 6 c-di-GMP biosynthesis D-glycerate acetylglucosamine ribose-phosphate uridylyltransferase: 6 6 protein]-N - diphosphate 1D-myo-inositol UL81_RS01210 a long-chain α complex: UL81_RS02055 [+ 4 isozymes] CoA hydrolase: acetyl-CoA formate E2 protein] N lipoate E2 protein] N -S- a mature peptidoglycan a nascent peptidoglycan I: UL81_RS07295 phosphate a [phospholipid] cis GDP- -D- UL81_RS03780 2+ lipoyl-L-lysine fatty acid diphosphorylase/ pyrophosphokinase: -dihydrolipoyl- acetyltransferase:acetyldihydrolipoyl- γ RNase III Fe protoporphyrin IX nitrate RS01465 nitrate trans,octacis- 1-acyl-sn-glycerol- -olefinic fatty acid long-chain fatty mannose UL81_RS02065 UL81_RS02075 (3Z)-dodec- UL81_RS03915 with (L-alanyl- -D-glutamyl- (meso-DAP containing) an [HPr protein]- an mRNA fragment a DNA containing acetaldehyde nitrite stearate glucosamine-1- UL81_RS04085 6 phosphate L-lysine L-lysine processing an alkylated cyclopropane- UDP-α-D-glucose an N -L- UL81_RS08175 meso-2,6-diaminopimeloyl- with GlcNAc terminus π decaprenyl phosphate 3-phosphate acid--CoA ligase: PRPP 3-enoyl-CoA acetyltransferase: N -phospho- pyruvate an apurinic/ fatty-acyl- phosphate N- 37 3-hydroxypropanoate mRNA nucleobase α acyltransferase: UL81_RS08430 threonylcarbamoyladenine ∆3,∆2-enoyl- D-alanine) tetrapeptide L-histidine a leader sequence a peptide apyrimidinic site a 2-O-(6-O-acyl- - polyprenol long-chain-fatty- phospholipid acetyltransferase UL81_RS10125 D-mannosyl)-6-O-[α- UL81_RS07820 in tRNA CoA isomerase: monophosphomannose acid--CoA ligase: synthase: a long-chain[+ 4 isozymes] GlmU: D-mannosyl-(1->6) UL81_RS01220 1-acyl-sn-glycerol- UL81_RS03965 acetyl phosphate acetyl-CoA synthase: UL81_RS05850 a [phospholipid]UL81_RS05815 fatty acyl-CoA UL81_RS04090 -α-D-mannosyl]- trans,octacis- UL81_RS01225 3-phosphate (2E)-dodec- UDP-N-acetyl- decaprenyl-diphospho-N- RNase E mRNA an all-trans- a peptide with 6-O-trans- fatty acid containing UDP-N-acetyl- a pentaglycine cross- a protein with a [phospholipid]- 1-phosphatidyl- decaprenylphospho- [+ 4 isozymes] acyltransferase: α 2-enoyl-CoA 3-oxopropanoate acetate kinase: α-D-glucosamine acetylmuramoyl-pentapeptide processing 1,4-dihydroxy- polyisoprenyl an N-terminal a uracil in DNA methoxy-mycolyl- roseoflavin histidinol cyclopropane -D-glucosamine bridge of peptidoglycan LAXTG motif palmitoleate 1D-myo-inositol β-D-mannose UL81_RS10665 enoyl-CoA UL81_RS10120 substrate 2-naphthoate diphosphate Xaa-L-proline cyclopropane- trehalose 6- bifunctional histidinol stearoyl-CoA a 1,2-diacyl- malonate hydratase: undecaprenyldiphospho- fatty-acyl- phosphate riboflavin kinase/ dehydrogenase: sn-glycerol semialdehyde acetate uracil-DNA trehalose- UL81_RS03965 muramoylpentapeptide beta-N- class E sortase: 1,4-dihydroxy- leucyl phospholipid FAD synthetase: UL81_RS07515 3-phosphate dehydrogenase: ribonuclease E: glycosylase: phosphatase: UL81_RS07055 (S)-3- acetylglucosaminyltransferase: UL81_RS10955 2-naphthoate aminopeptidase: synthase: α phosphatidate UL81_RS04005 UL81_RS08690 UL81_RS05335 trehalose-UL81_RS09690 roseoflavin a 2-O-(6-O-acyl- -D- Nucleoside and Nucleotide Biosynthesis hydroxydodecanoyl-CoA UL81_RS07715 polyprenyltransferase: UL81_RS07900 UL81_RS05815 his α cytidylyltransferase: a [phospholipid]-8- trans-methoxy- 5'-phosphate mannosyl)-6-O-[ -D- acetyl-CoA UL81_RS01395 α UL81_RS07230 3-hydroxy-2- a protein with LAXT (2-hexylcyclopropyl) mono-mycolate mannosyl-(1->6)- - biotin-carboxyl carrier superpathway of guanosine decaprenyl-pyrophosphoryl- a peptide with an RNase E an apyrimidinic uracil a CDP- superpathway of inosine-5'-phosphate biosynthesis I pyrimidine deoxyribonucleotides pyrimidine deoxyribonucleotides adenine and superpathway of 5-aminoimidazole and adenine and methylbutyryl-CoA Alcohol Degradation UDP carboxyl end attached an mRNA fragment a peptide with octanoate D-mannosyl-(1->6) protein assembly nucleotides de novo biosynthesis I superpathway of pyrimidine (N-acetylglucosamine)-N- N-terminal glycine processing a proteinogenic site in DNA α diacylglycerol adenosine nucleotides de novo biosynthesis I de novo biosynthesis III adenosine salvage III ribonucleotide biosynthesis guanosine salvage adenosine salvage I dehydrogenase: to a pentaglycine cross- an N-terminal a vitamin a vitamin - -D-mannosyl]- nucleobases salvage acetylmuramyl-(pentapeptide) product mRNA DMKH amino acid RS02745 a [biotin carboxyl- de novo biosynthesis I UL81_RS03990 bridge of peptidoglycan 2 L-proline uracil uracil 1-phosphatidyl- AIR UDP CTP UDP CTP uracil glycerol and glycerophosphodiester degradation 1D-myo-inositol carrier protein]-L-lysine PRPP IMP 5-(carboxyamino) class 1b nucleoside class 1b nucleoside uracil guanosine adenosine 3-oxododecanoyl-CoA biotin--[acetyl- IMP adenine amidophosphoribosyltransferase: asp imidazole ribonucleotide ribonucleoside- triphosphate ribonucleoside- triphosphate phosphoribosyltransferase: purine-nucleoside purine-nucleoside an N 10 - poly-[(R)-3- all-trans- a peptidoglycan a cytidine 1402 6-O-trans-keto- a (1->4)- CoA-carboxylase] purine-nucleoside UL81_RS09530 acetyl-CoA C- glycerol a glycerophosphodiester an L-methionyl- H O an oligopeptide IMP synthase: UL81_RS02530 hydrolase: hydrolase: diphosphate 2 dodecaprenyl 1,4-dihydroxy- dimer (generic) mycolyl-trehalose α-D-glucan diphosphate diphosphate : 5-phospho-β- UL81_RS02360 phosphorylase: phosphorylase: [initiator tRNA Met ] formyltetrahydrofolate hydroxybutanoate] in 16S rRNA GTP ligase: dehydrogenase: N5-CAIR acyltransferase: diphosphate 2-naphthoate 16S rRNA 6-phosphate 1,4-alpha-glucan a 2-O-(6-O-acyl-α-D- reductase: UL81_RS04145 reductase: UL81_RS04145 UL81_RS08230 D-ribosylamine bifunctional pyr operon UL81_RS08230 UL81_RS08230 S9 family UL81_RS02515 UL81_RS02120 adenylosuccinate CDP CDP UL81_RS03955 glycerophosphodiester (cytosine(1402)-N(4) adenylate/guanylate trehalose- branching mannosyl)-6-O-[α-D- a [biotin carboxyl- UL81_RS09125 UL81_RS09125 adenosine transcriptional regulator/uracil guanine adenine endolytic peptidase: synthase: 5-(carboxyamino) phosphoribosylamine- [+ 4 isozymes] phosphodiesterase: poly(3- inorganic )-methyltransferase cyclase domain- phosphatase: protein GlgB: mannosyl-(1->2)-α- carrier protein]-N UL81_RS09135 UL81_RS09135 phosphoribosyltransferase methionyl-tRNA 1,4-dihydroxy- transglycosylase UL81_RS09595 XMP UL81_RS10150 imidazole ribonucleotide class 1b class 1b -glycine ligase: glycerol UL81_RS10720 hydroxybutyrate) pyrophosphatase: RsmH: containing protein: UL81_RS09690 UL81_RS04960 D-mannosyl-(1->6)- 6 -biotinyl-L-lysine dUDP dUDP adenosine PyrR: UL81_RS06330 hypoxanthine adenine decanoyl-CoA formyltransferase: 2-naphthoate MltG: trehalose- mutase: UL81_RS02535 ribonucleoside- ribonucleoside- UL81_RS09625 depolymerase: UL81_RS09925 UL81_RS07755 UL81_RS01040 a peptide a glycogen α-D-mannosyl-(1->6) deaminase: UMP phosphoribosyltransferase: phosphoribosyltransferase: glycerophosphodiester UL81_RS06265 polyprenyltransferase: UL81_RS06395 4 trans-keto- nucleoside- diphosphate nucleoside- diphosphate UL81_RS09740 an N - cyclic-GMP -α-D-mannosyl]- glutamine- adenylo-succinate CAIR UL81_RS02335 GAR UL81_RS09910 UL81_RS06520 acyl-CoA glycerol kinase: phosphodiesterase: UL81_RS01395 1402 mono-mycolate diphosphate reductase: diphosphate reductase: (d)CMP kinase: methylcytidine 1-phosphatidyl- hydrolyzing dehydrogenase: UL81_RS10650 UL81_RS03830 an N-formyl- in 16S rRNA a [biotin carboxyl- kinase: UL81_RS09125 kinase: UL81_RS09125 UL81_RS05655 H + GlcNAc-1,6- 1D-myo-inositol GMP synthase: adenylosuccinate phosphoribosylaminoimidazolesuccinocarboxamide inosine GMP AMP UL81_RS04645 Aromatic Compound Degradation L-methionyl- a tetrahydrofolate (R)-3- poly-[(R)-3- phosphate a lipid II carrier-protein dimer]- lyase: UL81_RS08700 UL81_RS09135 UL81_RS08700 UL81_RS09135 UMP kinase: anhydro-MurNAc- UL81_RS02130 synthase: UL81_RS09615 [+ 3 isozymes] sn-glycerol [initiator tRNA met ] hydroxybutanoate hydroxybutanoate] DMK-12 N 6 -biotinyl-L-lysine pentapeptide UL81_RS09620 dUTP dCDP dUTP dCDP purine-nucleoside UL81_RS07240 protocatechuate degradation 3-phosphate acetyl-CoA biotin GMP SAICAR FGAR (2E)-dec-2-enoyl-CoA carboxylase: carboxylase: dUTP nucleoside- dUTP nucleoside- phosphorylase: UDP guanine and II (ortho-cleavage pathway) a 2-O-(6-O-acyl-α-D- a [glycine-cleavage N-acetyl-β-D-glucosamine- all-trans- 527 6-O-cis-methoxy- a (1->4)- UL81_RS02575 UL81_RS02575 AMP diphosphatase: diphosphate diphosphatase: diphosphate UL81_RS08230 phosphoribosylformylglycinamidine nucleoside-diphosphate guanosine salvage II enoyl-CoA O-succinyl-L- a guanine a supercoiled mannosyl)-6-O-[α-D- adenylosuccinate a sulfurated [sulfur carrier] SAM complex H protein] a charged tRNA a peptidyl-[tRNA] 1,6-anhydro-N- tridecaprenyl 1,4-dihydroxy- mycolyl-trehalose α-D-glucan a [carboxyl-carrier guanylate kinase: UL81_RS06715 kinase: UL81_RS06715 kinase: synthase: UL81_RS09570 kinase: UL81_RS08700 hydratase: protocatechuate homoserine in 16S rRNA ATP duplex DNA mannosyl-(1->2)-α- lyase: UL81_RS09620 N 6 -octanoyl-L-lysine acetyl-β-D-muramate diphosphate 2-naphthoate 16S rRNA 6-phosphate replicative 1,4-alpha-glucan 6 adenylate kinase: UL81_RS08700 UL81_RS08700 hypoxanthine protein dimer]-N - UL81_RS06295 dUMP dUMP UL81_RS09575 UL81_RS09580 UL81_RS03965 DHAP trehalose- branching D-mannosyl-(1->2)- UL81_RS01055 UTP guanosine (guanine(527)-N(7) adenylate/guanylate DNA helicase: α carboxybiotinyl-L-lysine AICAR dCTP dCTP (S)-3- phosphatase: protein GlgB: -D-mannosyl-(1->6) adenylate kinase: thymidylate thymidylate hypoxanthine FGAM 3-carboxy-cis beta-N- 1,4-dihydroxy- cystathionine )-methyltransferase cyclase domain- UL81_RS11050 α hydroxydecanoyl-CoA lipoyl synthase: transpeptidase: UL81_RS09690 UL81_RS04960 - -D-mannosyl-(1->6) GDP UL81_RS01920 bifunctional synthase: synthase (FAD): phosphoribosyltransferase: xanthine and ,cis-muconate acetylglucosaminidase: 2-naphthoate gamma-synthase: RsmG: containing protein: trehalose- [+ 9 isozymes] -α-D-mannosyl]- UL81_RS03620 UL81_RS07025 phosphoribosylformylglycinamidine (S)-3- UL81_RS07935 UL81_RS08965 UL81_RS11390 UL81_RS01040 a single starch phosphoribosylaminoimidazolecarboxamide UL81_RS09910 xanthosine salvage UL81_RS10405 polyprenyltransferase: UL81_RS08865 an N 7 - cis-methoxy- 1-phosphatidyl- cyclo-ligase: UL81_RS09525 CTP guanine hydroxydecanoyl- cyclic-AMP stranded DNA ADP formyltransferase/IMP dTMP dTMP UL81_RS01395 methylguanine 527 mono-mycolate 1D-myo-inositol CMP CoA a [glycine-cleavage nucleoside- class 1b cyclohydrolase PurH: UL81_RS03690 IMP (2-carboxy- a peptidyl- an uncharged in 16S rRNA thymidylate thymidylate phosphorylation AIR xanthosine hypoxanthine dehydrogenase: 5'-deoxyadenosine complex H protein] an unsulfurated 1,6-anhydro-N- GlcNAc diphosphate ribonucleoside- class 1b 2,5-dihydro- met aminoacyl-[tRNA] tRNA β L-homocysteine succinate FAICAR kinase: kinase: phosphoribosyltransferase: UL81_RS03990 6 [sulfur carrier] acetyl- -muramate kinase: diphosphate purine-nucleoside 5-oxofuran- N -lipoyl-L-lysine DMKH2-13 ribonucleoside- UL81_RS03085 UL81_RS03085 CMP pyrimidine deoxyribonucleotide UL81_RS09910 UL81_RS08700 reductase: phosphorylase: 2-yl)-acetate diphosphate bifunctional (d)CMP kinase: phosphorylation 3-oxodecanoyl-CoA UL81_RS09125 dTDP dTDP UL81_RS08230 4-carboxymuconolactone reductase: phosphoribosylaminoimidazolecarboxamide UL81_RS05655 GMP acetyl-CoA C- a 2,3,4-saturated 966 UDP-N-acetyl- a protein-L- UL81_RS09135 UL81_RS09125 formyltransferase/IMP nucleoside- nucleoside- CDP dTMP dCMP nucleosidase: decarboxylase: a guanine orotidine 5'- acyltransferase: methylmalonate semialdehyde hydrogen selenide O-acetyl-L-serine 1,2-diacyl-sn- 1,4-dihydroxy- GGPP a PII protein α-D-glucosamine methionine- (S)-malate GTP UL81_RS09135 cyclohydrolase PurH: UL81_RS03690 diphosphate diphosphate thymidylate (d)CMP kinase: UL81_RS10325 UL81_RS10780 in 16S rRNA phosphate nucleoside- xanthine UL81_RS03955 (4,5-dihydro- glycerol 3-phosphate CTP 2-naphthoate UTP 16S rRNA UDP-N- (R)-S-oxide malate kinase: kinase: kinase: UL81_RS05655 peptide- orotidine-5'- diphosphate dCDP 5-oxofuran- (guanine(966)-N(2) acetylglucosamine dehydrogenase dGDP dADP UL81_RS08700 UL81_RS08700 UL81_RS03085 [+ 4 isozymes] methionine (R)-S- phosphate IMP kinase: dTDP 2-yl)-acetate methylmalonate- cysteine 1,4-dihydroxy- )-methyltransferase 2-epimerase (non- (quinone): nucleoside- phosphatidate [protein-PII] oxide reductase: decarboxylase: dTTP dTTP UL81_RS08700 octanoyl-CoA semialdehyde synthase: 2-naphthoate RsmD: hydrolyzing): UL81_RS07155 nucleoside- diphosphate cytidylyltransferase: uridylyltransferase: UL81_RS06675 UL81_RS06305 nucleoside- nucleoside- CTP dehydrogenase (CoA UL81_RS01590 polyprenyltransferase: UL81_RS05350 UL81_RS08275 a [protein]-L- diphosphate kinase: Cell Structure Biosynthesis UL81_RS07230 glnD an N 2 - UDP-N-acetyl-α- oxaloacetate UMP diphosphate diphosphate acyl-CoA acylating): UL81_RS04005 UL81_RS01395 methionine UL81_RS08700 XMP 966 kinase: kinase: kinase: dehydrogenase: 3-oxoadipate methylguanine D-mannosamine UL81_RS08700 acetate in 16S rRNA UL81_RS08700 UL81_RS08700 dCTP UDP-N-acetylmuramoyl-pentapeptide UL81_RS04645 L-selenocysteine a CDP-2,3,4-saturated- a uridylylated + dTTP biosynthesis I (meso-diaminopimelate containing) [+ 3 isozymes] hydrogencarbonate NADH propanoyl-CoA H diacylglycerol demethylmenaquinol-4 PII protein dGTP dATP UDP-N-acetyl- (2E)-oct-2-enoyl-CoA α-D-glucosamine

UDP-N-acetylglucosamine enoyl-CoA 34 an [amino group carrier 34 lysine within 37 a guanine a single- a cytidine a [2-oxoglutarate-dehydrogenase an adenosine preQ γ (S)-dihydroorotate pyruvate 1-carboxyvinyltransferase: hydratase: a sulfurated [sulfur carrier] SAM gcv protein H an octanoyl-[acp] DMAPP 1 in tRNA stranded RNA protein]-C-terminal- - thr E2 protein] N 6 -octanoyl-L-lysine in tRNA in tRNA UL81_RS09380 UL81_RS03965 (L-ornithyl)-L-glutamate tRNA (cytidine(34) pyruvate L-histidine biosynthesis Amino Acid Biosynthesis α acetylornithine dihydroorotase: threonine L-tryptophan biosynthesis L-lysine biosynthesis I L-arginine biosynthesis I (via L-ornithine) L-arginine biosynthesis II (acetyl cycle) L-homoserine L-tyrosine UDP-N-acetyl- - (S)-3- -2'-O)- carboxylase: lipoate-protein tRNA-guanine(34) polynucleotide transaminase: pyrC dehydratase: biosynthesis biosynthesis I D-glucosamine- hydroxyoctanoyl-CoA tRNA (adenosine(37)-N6) methyltransferase: UL81_RS02425 lipoyl synthase: ligase B: transglycosylase: phosphorylase: argD UL81_RS07575 PRPP chorismate enolpyruvate 3-hydroxy-2- -dimethylallyltransferase an [amino group carrier a 2'-O- UL81_RS02215 asp glu N-acetylglutamyl-phosphate chorismate UL81_RS07935 UL81_RS07930 UL81_RS00755 UL81_RS07040 N-carbamoyl- oxaloacetate UDP-N- MiaA: UL81_RS06895 γ 34 2-oxobutanoate ATP N-acetyl-gamma-glutamyl- asp methylbutyryl-CoA protein]-C-terminal- -(L- methylcytidine L-aspartate anthranilate aspartate kinase: chorismate acetylenolpyruvoylglucosamine phosphoribosyltransferase: bifunctional phosphate reductase: mutase: dehydrogenase: a [glycine-cleavage a 7-aminomethyl-7- glutamate 5-semialdehyde- in tRNA UL81_RS00840 aspartate kinase: 6 37 a single- synthase UL81_RS05510 reductase: UL81_RS01190 UL81_RS03990 a [2-oxoglutarate dehydrogenase N -dimethylallyladenosine 34 a nucleoside 2-yl)-L-glutamate UL81_RS05960 glutamate N- acetylglutamate UL81_RS03660 5'-deoxyadenosine acyl-carrier protein complex H protein] deazaguanosine component II: UL81_RS00840 ala UDP-N-acetyl- met 6 an unsulfurated [sulfur carrier] guanine diphosphate stranded RNA L-aspartyl-4-phosphate bifunctional glutamatekinase: N- UL81_RS05520 E2 protein] N -lipoyl-L-lysine N 6 -octanoyl-L-lysine in tRNA in tRNA 1-(5-phospho- UL81_RS11250 acetyltransferase/ L-aspartyl- prephenate α-D-muramate 3-oxooctanoyl-CoA β-D-ribosyl)-ATP amino-acid acetyltransferase/amino- 4-phosphate prephenate anthranilate aspartate- acetyltransferase acid acetyltransferase UDP-N- glu acetyl-CoA C- semialdehyde ArgJ: ArgJ: UL81_RS05515 aspartate- dehydrogenase: acyltransferase: an [amino group carrier 6-O-α-mycolyl- acetylmuramate-- a [pyruvate dehydrogenase E2 an (S)-2- 3-(N-morpholino) a uracil 1498 anthranilate dehydrogenase: glu N-acetyl-L-glutamate N-acetyl-L-glutamate 5-semialdehyde semialdehyde UL81_RS00715 UL81_RS03955 methanethiol O-succinyl-L- orotidine 5'- γ wound RNA acetyl-CoA UL81_RS05515 L-alanine ligase: glutamate a sulfurated [sulfur carrier] SAM 6 protein]-C-terminal- - trehalose 6- β 3-(4- protein] N -octanoyl-L-lysine homoserine phosphate halocarboxylate propanesulfonate in 16S rRNA 1-(5-phospho- - phosphoribosyltransferase: UL81_RS00845 dehydrogenase: racemase: [+ 4 isozymes] (L-glutamyl)-L-glutamate 16S rRNA ATP-dependent phosphate N-acetyl-L- hydroxyphenyl) UL81_RS07710 acetyl-CoA D-ribosyl)-AMP UL81_RS11255 UL81_RS00845 UL81_RS09080 acetylglutamate (uracil(1498)-N(3))- RNA helicase: trehalose- N-(5- L-aspartate 4- glutamate superpathway of branched chain amino acid biosynthesis pyruvate alkanesulfonate carboxylase: phosphoribosyl- UDP-N-acetyl- hexanoyl-CoA cystathionine orotate haloacid kinase: methyltransferase: UL81_RS00425 phosphatase: phosphoribosyl) semialdehyde bifunctional glutamate N- acetylornithine L-aspartate 4- monooxygenase: UL81_RS02575 AMP acetylglutamate α-D-muramoyl- D-glt lipoyl synthase: gamma-synthase: phosphoribosyltransferase: dehalogenase: UL81_RS05520 UL81_RS08395 UL81_RS09690 acetyltransferase/amino- transaminase: argD semialdehyde acyl-CoA an [amino group carrier an N 3 - [+ 2 isozymes] α α cyclohydrolase: -anthranilate 4-hydroxy- kinase: pyruvate gln L-alanine UL81_RS07935 UL81_RS08865 UL81_RS10185 UL81_RS02970 UL81_RS00035 , '-trehalose malonyl-CoA thr acid acetyltransferase homoserine dehydrogenase: protein]-C-terminal- methyluracil 1498 an unwound RNA α UL81_RS07470 bifunctional 1-(5- tetrahydrodipicolinate UL81_RS05520 [+ 3 isozymes] 6- -mycolate ArgJ: UL81_RS05515 dehydrogenase: UL81_RS04645 γ-(5-phospho-L- in 16S rRNA 1-(5-phospho-β-D-ribosyl)- phosphoribosyl)-5-((5- synthase: acetolactate carbamoyl-phosphate tyr UDP-N- N-acetylglutamyl- threonine N-acetyl-L-ornithine UL81_RS04775 a [pyruvate dehydrogenase orotate 3-(N-morpholino) glutamyl)-L-glutamate 5-[(5-phosphoribosylamino) phosphoribosylamino) UL81_RS07020 synthase: synthase: carB acetylmuramoyl- [+ 3 isozymes] 5'-deoxyadenosine met succinate PRPP sulfite (2S,4S)-4- phosphate dehydratase: met 6 an unsulfurated [sulfur carrier] a (2R)-2- propanal methylideneamino)imidazole- UL81_RS05160 UL81_RS06315 L-alanine--D- E2 protein] N -lipoyl-L-lysine a halide anion methylideneamino]imidazole- hydroxy-2,3,4,5- UL81_RS07575 L-homoserine trans-hex-2-enoyl-CoA hydroxy fatty acid 4- carboxamide isomerase/ N-acetyl- UL81_RS05165 glutamate ligase: 4-carboxamide tetrahydrodipicolinate carbamoyl phosphate L-ornithine phosphoribosylanthranilate gamma-glutamyl- (2Z)-2-aminobut- UL81_RS07725 enoyl-CoA bifunctional 1-(5- 4-hydroxy- (S)-2-acetolactate isomerase PriA: phosphate 2-enoate glycine biosynthesis II hydratase: Carbohydrate Degradation UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N a [release factor]- an insertion sequence a [protein]-L- phosphoribosyl)-5-((5- tetrahydrodipicolinate coenzyme A [EntF L-seryl- NAD(P)H a plastoquinone H + coenzyme A isethionate + UL81_RS07485 reductase: UDP-N-acetyl- UL81_RS03965 -acetylmuramoyl-L-alanyl-γ- VibB ω GGPP NAD phosphoribosylamino) ketol-acid L-proline meso- carrier protein] L-glutamine element IS30 proline ( = 180) reductase: UL81_RS05510 a [glycine-cleavage α-D-muramoyl-L- D-glutamyl-L-lysyl- D-alanine peptide chain peptidylprolyl methylideneamino)imidazole- bifunctional indole-3-glycerol- reductoisomerase: biosynthesis I 6 diaminopimelate (S)-3- D-galactose degradation I (Leloir pathway) phytoene UL81_RS07030 N-acetyl-L- complex H protein] N -glycine cleavage transposase: isomerase: NAD kinase: 4- carboxamide isomerase/ phosphate synthase TrpC/ UL81_RS05170 ornithine (from L-glutamate) alanyl-D-glutamate hydroxyhexanoyl-CoA glycogen degradation II undecaprenyldiphospho- release factor synthase: (S)-2,3,4,5- glutamate 5- glycine cleavageaminomethyldihydrolipoyl- system protein T: holo-ACP NAD(P)H-quinone holo-ACP alkanesulfonate UL81_RS09300 UL81_RS00160 UL81_RS05600 phosphoribosylanthranilate phosphoribosylanthranilate (2R)-2,3- 2-iminobutanoate carbamoyltransferase: 3-hydroxyhexanoyl- muramoylpentapeptide beta-N- N(5)-glutamine UL81_RS01060 tetrahydrodipicolinate semialdehyde system protein T: L-lysine UL81_RS07920 UDP-N- β-D-galactopyranose synthase: dehydrogenase: synthase: monooxygenase: isomerase PriA: isomerase TrpF: dihydroxy-3- UL81_RS05530 glu CoA acetylglucosaminyltransferase: methyltransferase: an insertion [+ 2 isozymes] acetylornithine UL81_RS07920 acetylmuramoyl- a glycogen UL81_RS09000 UL81_RS02375 UL81_RS09000 UL81_RS00035 a [protein]-L- 15-cis-phytoene NADP + UL81_RS07485 UL81_RS11260 2,3,4,5- methylbutanoate glutamate glycine cleavage dehydrogenase: aldose UL81_RS07715 UL81_RS04880 sequence IS30 with transaminase: [+ 2 isozymes] L-alanyl-D- a [release factor]-N 5 proline (ω = 0) 1-(2- tetrahydropyridine- dihydroxy-acid 5-kinase: gly system protein H: UL81_RS03990 epimerase: glycogen/ integrated transposon phosphoribulosylformimino- 2,6-dicarboxylate N- argD glutamate--2, 6- a holo-[EntF -methyl-L-glutamine carboxyphenylamino) dehydratase: γ-L-glutamylUL81_RS08640 UL81_RS07925 UL81_RS06490 starch/alpha- ditrans,octacis-undecaprenyldiphospho- UDP a plastoquinol NAD(P) + a holo-[VibB aryl- glycolaldehyde sulfite AICAR-phosphate succinyltransferase: hydrogencarbonate N-acetyl-L- 2-oxobutanoate diaminopimelate 3',5'-ADP L-seryl-carrier 3',5'-ADP -1-deoxy-D-ribulose UL81_RS05150 5-phosphate 3-oxohexanoyl-CoA glucan family N-acetyl-(N-acetylglucosaminyl)muramoyl- carrier protein] UL81_RS04465 ornithine ligase: α-D-galactopyranose γ protein] 5-phosphate carbamoyl- 3-methyl-2- acetolactate L-citrulline a [glycine-cleavage a [glycine-cleavage phosphorylase: L-alanyl- -D-glutamyl-L-lysyl-D-alanine imidazole glycerol indole-3-glycerol- glutamate-5- D-ala UL81_RS07740 acetyl-CoA C- N-succinyl-2-amino- phosphate acetylornithine oxobutanoate synthase: complex H protein] complex H protein] N 6 UL81_RS07445 phosphate phosphate semialdehyde acyltransferase: galactokinase: 6-ketopimelate deacetylase: UL81_RS05160 argininosuccinate N 6 -lipoyl-L-lysine -dihydrolipoyl-L-lysine a 3,5,7,9,11,13,15- 6-O-cis-keto- synthase: carB D-alanine--D- α a [2-oxoglutarate dehydrogenase E2 3-aci- + synthase: synthase: dehydrogenase: L-alanine UDP-N-acetyl- UL81_RS03955 UL81_RS08130 an -limit dextrin phylloquinone NAD(P)H H coenzyme A uroporphyrinogen-III DNA with lesion a phosphate citrate succinyldiaminopimelate UL81_RS06315 UL81_RS00350 2-isopropylmalate branched-chain UL81_RS05165 synthase: UL81_RS05540 6 hepta-oxo- mycolyl-trehalose UL81_RS07475 UL81_RS07460 UL81_RS08625 biosynthesis III alanine ligase A: α-D-muramoyl- [+ 4 isozymes] galactokinase: protein] N -dihydrolipoyl-L-lysine nitropropanoate monoester transaminase: synthase: amino acid 4-alpha- multifunctional oxoglutarate uroporphyrinogen-III hexadecanoyl-[PKS-acp] excinuclease 6-phosphate UL81_RS07490 carbamoyl (S)-2-aceto-2- UL81_RS05320 L-alanyl-γ-D- UL81_RS06470 aldo/keto trehalose- alkaline aconitate bifunctional indole-3-glycerol- UL81_RS04430 L-ornithine UL81_RS00825 aminotransferase: L-arginino-succinate L-glutamate-5- glucanotransferase: decarboxylase/oxoglutarate C-methyltransferase: ABC subunit UvrA: phosphate hydroxybutanoate glutamyl-meso-2,6- butanoyl-CoA nitronate NAD(P)H-quinone reductase: phosphatase: phosphatase: hydratase: phosphate synthase TrpC/ semialdehyde glycine cleavage cys D-alanyl-D-alanine α UL81_RS08435 dehydrogenase thiamine CoA pyrophosphatase: UL81_RS03060 UL81_RS01490 D-erythro-1- N-succinyl-L,L-2,6- UL81_RS07895 ketol-acid diaminopimelate -D-galactose monooxygenase: dehydrogenase: UL81_RS08800 UL81_RS11735 acnA phosphoribosylanthranilate (2S)-2- argininosuccinate system protein T: cysteine acyl-CoA UDP-α-D-glucose pyrophosphate-binding UL81_RS00920 [+ 2 isozymes] UL81_RS09690 AICAR (imidazol-4- diaminopimelate reductoisomerase: 1-phosphate a debranched UL81_RS04045 UL81_RS02375 uroporphyrin-III 9-hydroxy-3,5,7,11,13,15-[+ 2 isozymes] isomerase TrpF: ornithine isopropylmalate lyase: UL81_RS05545 UL81_RS07920 desulfurase: dehydrogenase: α subunit/dihydrolipoyllysine- DNA without trehalose-cis-keto- an alcohol D-threo-isocitrate yl)-glycerol succinyl- UL81_RS05170 UDP-N- -limit dextrin methyltransferase: hexaoxohexadecanoyl- UL81_RS11260 carbamoyltransferase: val UL81_RS04995 UL81_RS04645 residue succinyltransferase lesion mono-mycolate 3-phosphate diaminopimelate 3-isopropylmalate [+ 2 isozymes] acetylmuramoyl- UL81_RS01295 [PKS-acp] (1S,2R)-1- UL81_RS05530 (R)-2,3-dihydroxy- arg (S)-1-pyrroline- cysteine [+ 3 isozymes] glycogen/ subunit: UL81_RS04550 [unspecified imidazoleglycerol- desuccinylase: dehydratase: tripeptide-- 3-oxopropanoate nitrite NAD(P) + phylloquinol 3',5'-ADP 4'-phosphopantetheine precorrin-2 C-(indol-3- 3-methylpentanoate 5-carboxylate desulfurase: starch/alpha- a [2-oxoglutarate dehydrogenase E2 degradation phosphate UL81_RS04475 UL81_RS05300 D-alanyl-D- yl)glycerol dihydroxy-acid UL81_RS06110 crotonyl-CoA glucan family protein] N 6 -S-succinyldihydrolipoyl-L-lysine products] dehydratase HisB: asp L-citrulline UL81_RS05305 pyrroline-5- alanine ligase: 3-phosphate dehydratase: ala phosphorylase: D-glucopyranose UL81_RS07505 L,L-diaminopimelate carboxylate UL81_RS07735 enoyl-CoA tryptophan 2-isopropylmaleate UL81_RS05150 UL81_RS07445 3-(imidazol-4- reductase: ammonia hydratase: 1402 α synthase a single a ribonucleoside a cytidine -D-glucosamine α yl)-2-oxopropyl diaminopimelate argininosuccinate (S)-3-methyl-2- L-methionine biosynthesis III UL81_RS01265 assimilation cycle III UL81_RS03965 a [formate C acetyltransferase]-glycine nicotinate PRPP a single a 9S rRNA reduced riboflavin -amylose formamide subunit beta: 3-isopropylmalate UDP-N-acetyl- α a reduced flavodoxin SAM stranded DNA triphosphate in 16S rRNA 6-phosphate phosphate epimerase: synthase: oxopentanoate α -D- stranded DNA flavin reductase: glucosamine- 1,4-alpha-glucan UL81_RS02850 dehydratase: -D-muramoyl- (S)-3- glucokinase: 16S rRNA UL81_RS06890 branched-chain pro γ glucopyranose branching formamidase: histidinol- UL81_RS05540 UL81_RS05300 ammonium glu L-alanyl- -D- hydroxybutanoyl-CoA (cytidine(1402)-2'-O) UL81_RS00050 6-phosphate tryptophan amino acid L-homoserine 1-phosphate UL81_RS07825 pyruvate formate-lyase exodeoxyribonuclease nicotinate protein GlgB: amiF phosphate UL81_RS05305 glutamyl-meso-2,6- (S)-3- ribonuclease E: -methyltransferase: sulfite reductase: deaminase: synthase: meso-diaminopimelate aminotransferase: superpathway of L-serine 1-activating : VII: UL81_RS04315 phosphoribosyltransferase: DNA primase: UL81_RS04960 transaminase: L-arginino- homoserine O- diaminopimeloyl- hydroxybutanoyl- UL81_RS08690 UL81_RS03820 UL81_RS03045 UL81_RS01700 UL81_RS11265 (2R,3S)-3- UL81_RS07895 and glycine biosynthesis I alpha-D-glucose UL81_RS09030 UL81_RS04320 UL81_RS09100 UL81_RS08285 a 2'-O- formate UL81_RS00655 succinate type I glutamate-- D-alanyl-D-alanine α 1402 F6P amylopectin UL81_RS11270 diaminopimelate isopropylmalate acetyltransferase: CoA UDP-glucose: - phosphate-specific methylcytidine riboflavin histidinol- argininosuccinate ammonia ligase: D-galactose- UDP-glucose 4- sucrose degradation III (sucrose invertase) decarboxylase: 3-isopropylmalate ile UL81_RS02230 dehydrogeanse: phosphoglucomutase: in 16S rRNA phosphate indole ser lyase: 3-phospho-(R)-glycerate UL81_RS07950 1-phosphate epimerase GalE: a [formate C acetyltransferase]- a ribonucleoside a single-stranded ssDNA/pppN(pN) a 5S rRNA an rRNA fragment UL81_RS01580 dehydrogenase: O-acetyl-L- phosphoglycerate UL81_RS03990 UL81_RS09335 5'-deoxyadenosine NaMN transaminase: UL81_RS05545 [+ 2 isozymes] uridylyltransferase: UL81_RS06790 a flavodoxin semiquinone glycin -2-yl radical met 5'-monophosphate oligodeoxyribonucleotide hybrid diaminopimelate UL81_RS05225 homoserine hydrogen sulfide dehydrogenase: [+ 2 isozymes] sucrose n -1 UL81_RS07510 acetoacetyl-CoA α-D-glucopyranose UL81_RS06475 tryptophan decarboxylase: arg (2S)-2-isopropyl- UL81_RS05220 UDP-α-D-galactose L-histidinol UL81_RS04770 3-phosphooxypyruvate acetyl-CoA C- 1-phosphate synthase 3-oxosuccinate O-acetylhomoserine gln sucrase 6 phosphate UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- a [protein]- an O - an (R)-2- (S)-4-amino-5- a (1->4)- phosphoenol cytidine subunit beta: L-cysteine superpathway of L- sulfhydrylase: acyltransferase: ferredoxin: γ a ribonucleic acid chitin NMN α phosphoserine alpha-D-glucose D-glucopyranose alanyl- -D-glutamyl-L-lysyl- D-alanyl-D-alanine L-cysteine methylguanine halocarboxylate oxopentanoate -D-glucan pyruvate histidinol- UL81_RS02850 lys biosynthesis I asparagine biosynthesis UL81_RS02235 glutamate UL81_RS02700 UL81_RS02160 1,4-alpha-glucan nucleoside transaminase: synthase phosphate-specific 6-phosphate in DNA bifunctional glutamate-1- deaminase: phosphatase: tryptophan [+ 4 isozymes] N-acetylneuraminate and beta-fructosidase: undecaprenyldiphospho- metallophosphatase/ semialdehyde- branching pyruvate kinase: 4-methyl-2- UL81_RS03495 subunit beta: gltD phosphoglucomutase: HAD family beta-N- UL81_RS00725 UL81_RS03310 synthase: L-threonine asp N-acetylmannosamine UL81_RS04505 muramoylpentapeptide beta-N- cysteine ribonuclease PH: 5'-nucleotidase: 2,1-aminomutase: protein GlgB: UL81_RS07450 ser oxopentanoate acetyl-CoA UL81_RS09335 hydrolase: acetylglucosaminidase: UL81_RS11265 biosynthesis serine O- L-homocysteine O-phospho-L-serine L-glutamate degradation I acetylglucosaminyltransferase: methyltransferase: UL81_RS09070 UL81_RS06505 UL81_RS01340 UL81_RS04960 uridine histidinol branched-chain glu [+ 2 isozymes] UL81_RS03910 UL81_RS10405 1-(β-D UL81_RS11270 acetyltransferase: biosynthesis III β UL81_RS07715 UL81_RS03275 a GlgE-glycogen pyruvate alanine amino acid N-acetylneuraminate -D-fructofuranose D-glucopyranose ribofuranosyl) 5-aminolevulinate histidinol L-homoserine UL81_RS09395 asparagine asparagine methionine phosphoserine D-glucopyranose racemization aminotransferase: synthase: 5-methyltetrahydropteroyltriglutamate- 6-phosphate N-acetyl-D- nicotinamide dehydrogenase: homoserine O-acetyl-L-serine synthase synthase phosphatase SerB: 2-oxoglutarate glucokinase: ditrans,octacis-undecaprenyldiphospho-N- UDP a [protein]-S- an (S)-2- a nucleoside a ribonucleic acid chitin UL81_RS07895 - homocysteine S- β a guanine in DNA a halide anion glucosamine UL81_RS07515 trp kinase: (glutamine- (glutamine- UL81_RS07590 UL81_RS09115 glutamate synthase N-acetyl-D- UL81_RS07825 acetyl-(N-acetyl- -D-glucosaminyl)muramoyl-L- methyl-L-cysteine hydroxycarboxylate diphosphate methyltransferase: UL81_RS00155 γ ala UL81_RS04780 cysteine synthase hydrolyzing): hydrolyzing): methionine subunit beta: gltD mannosamine D-glucopyranose alanyl- -D-glutamyl-L-lysyl-D-alanyl-D-alanine alanine O-phospho- leu [+ 2 isozymes] histidinal A: UL81_RS09390 UL81_RS07875 UL81_RS07875 synthase: ser NADP-specific 6-phosphate racemase: L-homoserine cysteine synthase: UL81_RS05015 glutamate a [2-oxoglutarate histidinol UL81_RS02050 threonine serine D-mannose degradation glucose-6- an L-1- an (S-diacyl-sn- 5-amino-4- an (S)-2- an (R)-2- a glucosylated UL81_RS01590 dehydrogenase: N-acetyl-D- PRPP dehydrogenase E2 protein] a [protein] Ser/Thr a uridine in tRNA prephenate dehydrogenase: D-ala synthase: hydroxymethyltransferase: phosphate phosphatidylethanolamine glyceryl)-L-cysteinyl- imidazolecarboxyamide halocarboxylate halocarboxylate asn asn met UL81_RS07425 mannosamine N 6 -dihydrolipoyl-L-lysine serine/threonine 1,4-alpha-glucan UL81_RS07515 UL81_RS08085 UL81_RS04240 D-mannopyranose isomerase: [apolipoprotein] tRNA prephenate cys glu 6-phosphate dihydrolipoyl protein kinase: dihydrouridine branching 6-phosphate UL81_RS03650 adenine HAD family HAD family dehydratase: mannose-6- putative N- apolipoprotein N- dehydrogenase: UL81_RS07800 synthase DusB: protein GlgB: his thr gly phosphoribosyltransferase: hydrolase: hydrolase: UL81_RS10695 phosphate acetylmannosamine- acyltransferase: UL81_RS01125 [+ 4 isozymes] UL81_RS09455 UL81_RS04960 F6P UL81_RS06520 UL81_RS03910 UL81_RS03910 a [2-oxoglutarate 3-phenyl-2- isomerase, class 6-phosphate UL81_RS05855 a [protein] (L-serine/L- a 5,6-dihydrouridine a glycogen I: UL81_RS03070 dehydrogenase E2 oxopropanoate 2-epimerase: 6 threonine) phosphate in tRNA F6P protein] N -lipoyl-L-lysine UL81_RS01685 a 2-acyl-1-lyso- an N-acyl-(S-diacyl- an (S)-2- a (2R)-2- N-acetyl-D- AICAR a halide anion a halide anion phosphatidylethanolamine sn-glyceryl)-L- hydroxycarboxylate hydroxy fatty acid glucosamine cysteinyl-[lipoprotein] 6-phosphate

D-threo-7,8- 3-hydroxy- UDP-N-acetyl-α-D-muramoyl- D-alanyl-D-alanine D-glucopyranose maltopentaose H O a ribonucleoside long chain (2R,3S)-3- 5-aminolevulinate ethanol L-alanyl-γ-D-glutamyl-L-lysine dihydroneopterin isobutanoyl-CoA 2 5'-monophosphate polyphosphate isopropylmalate purine nucleotides degradation II (aerobic) Nucleoside and Nucleotide Degradation bifunctional 3-isopropylmalate porphobilinogen dehydratase: catalase: 4-alpha- dihydroneopterin 3-hydroxyisobutyryl- metallophosphatase/ exopolyphosphatase: synthase: UDP-N-acetylmuramoyl- UL81_RS08860 UL81_RS05300 UL81_RS00860 tripeptide--D-alanyl- glucanotransferase: aldolase: CoA hydrolase: 5'-nucleotidase: UL81_RS01300 AMP UL81_RS08435 UL81_RS06505 UL81_RS05305 D- alanine ligase: UL81_RS09890 UL81_RS03915 long chain (2S)-2- porphobilinogen acetaldehyde UL81_RS07735 a ribonucleoside polyphosphate isopropylmalate bifunctional IMP metallophosphatase/ maltose maltotetraose 6-(hydroxymethyl) glycolaldehyde 3-hydroxy- UDP-N-acetyl-α-D-muramoyl-L-alanyl- 5'-nucleotidase: IMP -7,8-dihydropterin isobutanoate γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine UL81_RS06505 dehydrogenase: GMP UL81_RS02120 adenosine a [histone]-N 6 - N,N',N''- an N-acetyl-β- RNase G NAD + D-glucopyranose maltohexaose protoporphyrinogen IX a DNA segment choline MeOH bifunctional XMP acetyl-L-lysine triacetylchitotriose D-hexosaminide degradation adenosine metallophosphatase/ protoporphyrinogen recombinase RecB: substrate mRNA choline UL81_RS10760 catalase: deaminase: 5'-nucleotidase: bifunctional NAD-dependent 4-alpha- beta-N- beta-N- oxidase: ribonuclease E: dehydrogenase: recombinase RecA: UL81_RS00860 UL81_RS02335 UL81_RS06505 metallophosphatase/ deacylase: glucanotransferase: acetylglucosaminidase: acetylglucosaminidase: UL81_RS01320 UL81_RS08690 UL81_RS00460 UL81_RS08435 UL81_RS10405 UL81_RS10405 UL81_RS06950 5'-nucleotidase: UL81_RS00400 protoporphyrin IX a DNA segment in betaine aldehyde formaldehyde inosine guanosine an mRNA fragment UL81_RS06505 reverse orientation N,N'- N-acetyl-D- an N-acetyl-β- 2''-O-acetyl- maltopentaose maltose an alcohol purine-nucleoside purine-nucleoside xanthosine ADP-ribose a [histone]-L-lysine nicotinamide diacetylchitobiose glucosamine D-hexosamine phosphorylase: phosphorylase: UL81_RS08230 UL81_RS08230 purine-nucleoside a [protein]-N 6 - a plant soluble RNase E NAD + D-glucopyranose maltotriose a glucan FMN NAD(P)H H + porphobilinogen NaMN ferroheme o nicotinamide hypoxanthine guanine phosphorylase: acetyl-L-lysine heteroglycan degradation UL81_RS08230 purine ribonucleosides degradation hydroxymethylbilane bifunctional substrate mRNA metallophosphatase/ heme A synthase: nicotinamidase: nucleosidase: NAD-dependent 4-alpha- 4-alpha- synthase: ribonuclease E: flavin reductase: 5'-nucleotidase: UL81_RS06150 UL81_RS08980 UL81_RS10325 deacylase: glucanotransferase: glucanotransferase: UL81_RS01290 UL81_RS08690 UL81_RS00050 UL81_RS06505 adenosine UL81_RS00400 UL81_RS08435 UL81_RS08435 β preuroporphyrinogen -D- an mRNA fragment ferroheme a nicotinate ribosylnicotinate xanthine adenosine 2''-O-acetyl- a plant soluble deaminase: maltose a glucan D-glucopyranose FMNH NAD(P) + ADP-ribose nicotinamide a [protein]-L-lysine heteroglycan 2 xanthosine UL81_RS02335

urate adenosine inosine guanosine a long-linear 3-methyl-2- 5,10-methylene- α + a negatively L-gulono- purine-nucleoside D-glucopyranose a maltodextrin -D-glucopyranose α FMN NADH H uroporphyrinogen-III uroporphyrinogen-I oxobutanoate tetrahydromethanopterin -D-glucan an acyl phosphate supercoiled DNA 1,4-lactone phosphorylase: uroporphyrinogen uroporphyrinogen type I DNA L-gulonolactone UL81_RS08230 purine-nucleoside purine-nucleoside purine-nucleoside 3-methyl-2-oxobutanoate 4-alpha- 4-alpha- decarboxylase: decarboxylase: acylphosphatase: topoisomerase: oxidase: nucleosidase: phosphorylase: phosphorylase: phosphorylase: flavin reductase: UL81_RS07390 UTP and CTP dephosphorylation I hydroxymethyltransferase: glucanotransferase: glucanotransferase: UL81_RS01315 UL81_RS01315 UL81_RS01025 UL81_RS04360 UL81_RS10325 UL81_RS08230 UL81_RS08230 UL81_RS08230 UL81_RS08735 UL81_RS08435 UL81_RS08435 UL81_RS00050 coproporphyrinogen III coproporphyrinogen I a carboxylate a relaxed DNA L-ascorbate UTP α-D-ribose- a short 1,4- 1-phosphate a maltodextrin maltose FMNH NAD + 2-dehydropantoate THMPT α-D-glucan 2 nucleoside α-D-ribose 1,5- triphosphate phosphomutase: CTP hydrolase: UL81_RS08215 1518 β UL81_RS04145 an oxidized adenine / a -D- an organic a [protein] (L-serine/L- nucleoside D-ribose 5- N 5 -methyltetrahydromethanopterin D-glucopyranose maltotetraose oxaloacetate α-carotene oxaloacetate factor 420 adenine 1519 in 16S rRNA fructofuranoside hydroperoxide threonine) phosphate triphosphate phosphate 16S rRNA UDP phosphoenolpyruvate protein 2-methylcitrate hydrolase: (adenine(1518)-N(6)/ alkylhydroperoxidase: beta-hydroxylase: 4-alpha- carboxykinase (GTP) phosphatase: synthase: UL81_RS04145 5,10-methylenetetrahydromethanopterin adenine(1519)-N(6))- beta-fructosidase: UL81_RS08835 UL81_RS09790 reductase: UL81_RS06430 glucanotransferase: UL81_RS04505 : UL81_RS10460 UL81_RS00230 UL81_RS02410 CDP UL81_RS08435 dimethyltransferase phosphoenol (2S,3S)-2- UMP purine deoxyribonucleosides degradation I RsmA: UL81_RS03880 an alcohol a [protein] Ser/Thr zeinoxanthin N 6 -dimethyladenine 1518 pyruvate methylcitrate bifunctional /N 6 -dimethyladenine 1519 5,10-methylene- a reduced maltose maltotriose β-D-fructofuranose a metallophosphatase/ adenosine deaminase: tetrahydromethanopterin factor 420 in 16S rRNA CMP 5'-nucleotidase: UL81_RS02335 2'-deoxyadenosine bifunctional UL81_RS06505 2'-deoxyinosine 2'-deoxyguanosine 2,5-diamino-6-(5- an [amino group carrier protein]- lipid A lipid A metallophosphatase/ uridine seleno-L- a double D-ribofuranose phospho-D-ribitylamino) C-terminal-γ-(L-glutamate 5- (E. coli) disaccharide a cytosine in DNA N-ethylmaleimide 5'-nucleotidase: homocysteine stranded DNA purine-nucleoside pyrimidin-4(3H)-one semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- (P. putida) DNA cytosine DNA gyrase UL81_RS06505 bifunctional 5-methyltetrahydropteroyltriglutamate- tetraacyldisaccharide 4'- alkene reductase: ribokinase: purine-nucleoside phosphorylase: purine-nucleoside glutamyl-phosphate tetraacyldisaccharide 4'- methyltransferase: subunit A: cytidine diaminohydroxyphosphoribosylaminopyrimidine - homocysteine S- kinase: UL81_RS05560 UL81_RS02590 UL81_RS02540 phosphorylase: UL81_RS08230 phosphorylase: reductase: kinase: UL81_RS05560 UL81_RS04620 UL81_RS00075 adenosine deaminase/5-amino-6-(5-phosphoribosylamino) methyltransferase: UL81_RS00155 UL81_RS08230 UL81_RS08230 uracil reductase RibD: UL81_RS06250 an [amino group carrierUL81_RS05510 protein]- lipid IV (E. coli) lipid IV a 5-methylcytosine a negatively D-ribofuranose nucleotides A A N-ethylsuccinimide 5-amino-6-(5-phospho- SeMet C-terminal-γ-(5-phospho- (P. putida) in DNA supercoiled DNA 5-phosphate degradation III D-ribitylamino)uracil 2-deoxy-α-D-ribose 1-phosphate L-glutamyl)-L-glutamate AMP 34 N,N'- AMP 2-amino-6-[1-hydroxyethyl]- trans,octacis-decaprenylphospho- a 5-carboxymethylaminomethyluridine an α-limit dextrin (2R,3S)-3- 2'-deoxycytidine β Leu oxaloacetate 15-cis-phytoene nucleosidase: 7-methyl-7,8-dihydropterin -D-arabinofuranose in tRNA diacetylchitobiose isopropylmalate nucleoside UL81_RS00370 2-amino-4-hydroxy-6- decaprenylphospho-beta- tRNA (cytidine(34) beta-N- 4-alpha- 3-isopropylmalate phytoene citrate synthase: deaminase: adenine hydroxymethyldihydropteridine D-erythro-pentofuranosid- -2'-O)- acetylglucosaminidase: glucanotransferase: dehydrogenase: desaturase: UL81_RS03500 UL81_RS00725 diphosphokinase: UL81_RS09885 2-ulose 2-reductase: methyltransferase: UL81_RS10405 UL81_RS08435 UL81_RS05225 UL81_RS01065 [1-(2-amino-7-methyl-4-oxo- UL81_RS00545 UL81_RS02215 N-acetyl-D- a α-limit dextrin 2'-deoxyuridine trans,octacis-decaprenylphospho- a 5-carboxymethylaminomethyl- 1,2-dihydroxypropane- 4-methyl-2- 9,15,9'-tri-cis 7,8-dihydro-3H-pteridin- glucosamine with short branches 1,2,3-tricarboxylate oxopentanoate -ζ-carotene β-D-erythro-pentofuranosid-2-ulose 2'-O-methyluridine 34 in tRNA Leu a branched- 6-yl)]ethyl diphosphate chain a reduced a reduced an amino an amino amino acid acid acid a dicarboxylate a dicarboxylate plastocyanin plastocyanin a branched- a β- N-(4- phosphonate an amino an amino an amino an amino an amino an amino an oxidized an oxidized glycine betaine L-ascorbate phosphonate chain a C4- a C4- glucoside 6- lactose 6'- aminobenzoyl) an inorganic a sugar 6- D-galactose molybdate an amino acid acid acid acid acid acid chromate chromate a carbohydrate a carbohydrate plastocyanin plastocyanin a nucleotide a carboxylate gly 6-phosphate phosphite an aromatic amino acid dicarboxylate dicarboxylate phosphate phosphate -L-glutamate anion phosphate carboxylate acid predicted predicted predicted ABC predicted ABC ABC ABC transporter RS02635 RS02820 RS06485 RS04800 RS02955 transporter of RS10165 transporter transporter RS09670 RS02920 RS05550 RS04460 RS04470 RS11275 RS04370 RS08470 of a RS05950 RS05665 RS08885 RS10800 RS02495 RS02870 RS09120 RS07865 RS10135 RS06860 RS03375 RS02250 RS10270 RS02815 RS00695 phosphonate of an of an branched- amino acid amino acid a branched- chain N-(4- glycine betaine D-galactose phosphonate a C4- a C4- a carbohydrate a carbohydrate a β-glucoside lactose an inorganic a sugar L-ascorbate molybdate an aromatic an amino an amino an amino an amino chain amino acid chromate chromate aminobenzoyl) a nucleotide a carboxylate gly phosphite an amino acid acid acid acid an amino an amino dicarboxylate dicarboxylate O O anion phosphonate carboxylate amino acid 2 2 -L-glutamate an amino an amino acid acid acid H O H O a branched- 2 2 acid acid a dicarboxylate a dicarboxylate chain amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.