INIAstress Consortium Publications 2014

Anderson RI, Becker HC, Adams BL, Jesudason CD, Rorick-Kehn LM. Orexin-1 and orexin-2 receptor antagonists reduce ethanol self-administration in high-drinking rodent models. Front Neurosci. 2014 Feb 25;8:33. doi: 10.3389/fnins.2014.00033. eCollection 2014. PubMed PMID: 24616657; PubMed Central PMCID: PMC3933945.

Ashbrook DG, Williams RW, Lu L, Stein JL, Hibar DP, Nichols TE, Medland SE, Thompson PM, Hager R. Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease. BMC Genomics. 2014 Oct 3;15:850. doi: 10.1186/1471-2164-15-850. PubMed PMID: 25280473; PubMed Central PMCID: PMC4192369.

Asquith M, Pasala S, Engelmann F, Haberthur K, Meyer C, Park B, Grant KA, Messaoudi I. Chronic ethanol consumption modulates growth factor release, mucosal cytokine production, and microRNA expression in nonhuman primates. Alcohol Clin Exp Res. 2014 Apr;38(4):980-93. doi: 10.1111/acer.12325. Epub 2013 Dec 13. PubMed PMID: 24329418; PubMed Central PMCID: PMC3984381.

Baker EJ, Farro J, Gonzales S, Helms C, Grant KA. Chronic alcohol self-administration in monkeys shows long-term quantity/frequency categorical stability. Alcohol Clin Exp Res. 2014 Nov;38(11):2835-43. doi: 10.1111/acer.12547. PubMed PMID: 25421519; PubMed Central PMCID: PMC4244650.

Becker HC. Alcohol Dependence, Withdrawal, and Relapse. In: Noronha A, Cui C, Harris RA, Crabbe JC (Eds) Neurobiology of Alcohol Dependence. Academic Press (Elsevier), Waltham, MA, p. 377-410, 2014.

Becker HC, Mulholland PJ. Neurochemical mechanisms of alcohol withdrawal. Handb Clin Neurol. 2014;125:133- 56. doi: 10.1016/B978-0-444-62619-6.00009-4. Review. PubMed PMID: 25307573, PubMed Central PMCID: PMC5081257.

Becker HC, Ron D. Animal models of excessive alcohol consumption: recent advances and future challenges. Alcohol. 2014 May;48(3):205-8. doi:10.1016/j.alcohol.2014.04.001. Epub 2014 Apr 8. PubMed PMID: 24811154; PubMed Central PMCID: PMC5081257.

Boon AC, Williams RW, Sinasac DS, Webby RJ. A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice. BMC Genomics. 2014 Nov 24;15:1017. doi: 10.1186/1471-2164-15-1017. PubMed PMID: 25418976; PubMed Central PMCID: PMC4256927.

Burnett EJ, Grant KA, Davenport AT, Henby SE, Friedman DP. The effects of chronic ethanol self-administration on hippocampal 5-HT1A receptors in monkeys. Drug Alcohol Depend. 2014 Mar 1;136:135-42. doi: 10.1016/j.drugalcdep.2014.01.002. Epub 2014 Jan 15. PMID: 24467872. PMCID: PMC3962821.

Centanni SW, Teppen T, Risher ML, Fleming RL, Moss JL, Acheson SK, Mulholland PJ, Pandey SC, Chandler LJ, Swartzwelder HS. Adolescent alcohol exposure alters GABAA receptor subunit expression in adult hippocampus. Alcohol Clin Exp Res. 2014 Nov;38(11):2800-8. doi: 10.1111/acer.12562. PubMed PMID: 25421517; PubMed Central PMCID: PMC4244607.

Colombo G, Maccioni P, Acciaro C, Lobina C, Loi B, Zaru A, Carai MA, Gessa GL. Binge drinking in alcohol- preferring sP rats at the end of the nocturnal period. Alcohol. 2014 May;48(3):301-11. doi: 10.1016/j.alcohol.2014.02.001. Epub 2014 Mar 1. PubMed PMID: 24680256; PubMed Central PMCID: PMC4047429. Cook JB, Dumitru AM, O'Buckley TK, Morrow AL. Ethanol administration produces divergent changes in GABAergic neuroactive steroid immunohistochemistry in the rat brain. Alcohol Clin Exp Res. 2014 Jan;38(1):90-9. doi: 10.1111/acer.12223. Epub 2013 Jul 26. PubMed PMID: 23906006; PubMed Central PMCID: PMC4196317.

Cook JB, Nelli SM, Neighbors MR, Morrow DH, O'Buckley TK, Maldonado-Devincci AM, Morrow AL. Ethanol alters local cellular levels of (3α,5α)-3-hydroxypregnan-20-one (3α,5α-THP) independent of the adrenals in subcortical brain regions. Neuropsychopharmacology. 2014 Jul;39(8):1978-87. doi: 10.1038/npp.2014.46. Epub 2014 Feb 25. PubMed PMID: 24566803; PubMed Central PMCID: PMC4059907.

Cook JB, Werner DF, Maldonado-Devincci AM, Leonard MN, Fisher KR, O'Buckley TK, Porcu P, McCown TJ, Besheer J, Hodge CW, Morrow AL. Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self- administration. J Neurosci. 2014 Apr 23;34(17):5824-34. doi: 10.1523/JNEUROSCI.4733-13.2014. PubMed PMID: 24760842; PubMed Central PMCID: PMC3996211.

Costin BN, Miles MF. Molecular and neurologic responses to chronic alcohol use. Handb Clin Neurol. 2014;125:157- 71. doi: 10.1016/B978-0-444-62619-6.00010-0. Review. PubMed PMID: 25307574; PubMed Central PMCID: PMC4412740.

Daigle TL, Ferris MJ, Gainetdinov RR, Sotnikova TD, Urs NM, Jones SR, Caron MG. Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission. Neuropsychopharmacology. 2014 Sep;39(10):2450-62. doi: 10.1038/npp.2014.97. Epub 2014 Apr 29. PubMed PMID: 24776686; PubMed Central PMCID: PMC4138757.

Daunais JB, Davenport AT, Helms CM, Gonzales SW, Hemby SE, Friedman DP, Farro JP, Baker EJ, Grant KA. Monkey alcohol tissue research resource: banking tissues for alcohol research. Alcohol Clin Exp Res. 2014 Jul;38(7):1973-81. doi: 10.1111/acer.12467. Epub 2014 Jun 18. PubMed PMID: 24942558; PubMed Central PMCID: PMC4370268.

Diaz MR, Jotty K, Locke JL, Jones SR, Valenzuela CF. Moderate Alcohol Exposure during the Rat Equivalent to the Third Trimester of Human Pregnancy Alters Regulation of GABAA Receptor-Mediated Synaptic Transmission by Dopamine in the Basolateral Amygdala. Front Pediatr. 2014 May 27;2:46. doi: 10.3389/fped.2014.00046. eCollection 2014. PubMed PMID: 24904907; PubMed Central PMCID: PMC4035091.

Emery FD, Parvathareddy J, Pandey AK, Cui Y, Williams RW, Miller MA. Genetic control of weight loss during pneumonic Burkholderia pseudomallei infection. Pathog Dis. 2014 Jul;71(2):249-64. doi: 10.1111/2049-632X.12172. Epub 2014 Apr 22. PubMed PMID: 24687986; PubMed Central PMCID: PMC4107055.

Ewald ER, Wand GS, Seifuddin F, Yang X, Tamashiro KL, Potash JB, Zandi P, Lee RS. Alterations in DNA methylation of Fkbp5 as a determinant of blood-brain correlation of glucocorticoid exposure. Psychoneuroendocrinology. 2014 Jun;44:112-22. doi: 10.1016/j.psyneuen.2014.03.003. Epub 2014 Mar 20. PubMed PMID: 24767625; PubMed Central PMCID: PMC4047971.

Ferris MJ, España RA, Locke JL, Konstantopoulos JK, Rose JH, Chen R, Jones SR. Dopamine transporters govern diurnal variation in extracellular dopamine tone. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):E2751-9. doi: 10.1073/pnas.1407935111. Epub 2014 Jun 16. PubMed PMID: 24979798; PubMed Central PMCID: PMC4084435.

Ferris MJ, Milenkovic M, Liu S, Mielnik CA, Beerepoot P, John CE, España RA, Sotnikova TD, Gainetdinov RR, Borgland SL, Jones SR, Ramsey AJ. Sustained N-methyl-d-aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling. Eur J Neurosci. 2014 Jul;40(1):2255-63. doi:10.1111/ejn.12594. Epub 2014 Apr 23. PubMed PMID: 24754704; PubMed Central PMCID: PMC4331169.

Fish EW, Whitman BJ, DiBerto JF, Robinson JE, Morrow AL, Malanga CJ. Effects of the neuroactive steroid allopregnanolone on intracranial self-stimulation in C57BL/6J mice. Psychopharmacology (Berl). 2014 Sep;231(17):3415-3423. doi:10.1007/s00213-014-3600-8. Epub 2014 May 9. PubMed PMID: 24810108; PubMed Central PMCID: PMC4692244. Ford MM. Applications of schedule-induced polydipsia in rodents for the study of an excessive ethanol intake phenotype. Alcohol. 2014 May;48(3):265-76. doi: 10.1016/j.alcohol.2014.01.005. Epub 2014 Feb 28. Review. PubMed PMID: 24680665; PubMed Central PMCID: PMC4016177.

Grant K, Ferguson B, Helms C, McClintick M. Neurobiology of Alcohol Dependence. Noronha A, Cui C, Harris A, Crabbe JC, editors. San Diego: Academic Press; 2014. Chapter 20, Drinking to Dependence Risk Factors in Nonhuman Primates; p.408-420.

Graybeal C, Bachu M, Mozhui K, Saksida LM, Bussey TJ, Sagalyn E, Williams RW, Holmes A. Strains and stressors: an analysis of touchscreen learning in genetically diverse mouse strains. PLoS One. 2014 Feb 19;9(2):e87745. doi: 10.1371/journal.pone.0087745. eCollection 2014. PubMed PMID: 24586288; PubMed Central PMCID: PMC3929556.

Griffin WC 3rd. Alcohol dependence and free-choice drinking in mice. Alcohol. 2014 May;48(3):287-93. doi: 10.1016/j.alcohol.2013.11.006. Epub 2014 Jan 18. Review. PubMed PMID: 24530006; PubMed Central PMCID: PMC4032174.

Hait NC, Wise LE, Allegood JC, O'Brien M, Avni D, Reeves TM, Knapp PE, Lu J, Luo C, Miles MF, Milstien S, Lichtman AH, Spiegel S. Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. Nat Neurosci. 2014 Jul;17(7):971-80. doi: 10.1038/nn.3728. Epub 2014 May 25. PubMed PMID: 24859201; PubMed Central PMCID: PMC4256678.

Hall RA, Liebe R, Hochrath K, Kazakov A, Alberts R, Laufs U, Böhm M, Fischer HP, Williams RW, Schughart K, Weber SN, Lammert F. Systems genetics of liver fibrosis: identification of fibrogenic and expression quantitative trait loci in the BXD murine reference population. PLoS One. 2014 Feb 28;9(2):e89279. doi: 10.1371/journal.pone.0089279. eCollection 2014. PubMed PMID: 24586654; PubMed Central PMCID: PMC3938463.

Harenza JL, Muldoon PP, De Biasi M, Damaj MI, Miles MF. Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice. Genes Brain Behav. 2014 Feb;13(2):213-25. doi: 10.1111/gbb.12113. Epub 2013 Dec 26. PubMed PMID: 24289814; PubMed Central PMCID: PMC3919514.

Helms CM, Rau A, Shaw J, Stull C, Gonzales SW, Grant KA. The effects of age at the onset of drinking to intoxication and chronic ethanol self-administration in male rhesus macaques. Psychopharmacology (Berl.). 2014 Apr;231(8):1853-61. doi: 10.1107/s00213-013-3417-x. Epub 2014 Jan 22. PMID: 2448900. PMCID: PMC3969395.

Helms CM, Park B, Grant KA. Adrenal steroid hormones and ethanol self-administration in male rhesus macaques. Psychopharmacology (Berl). 2014 Sep;231(17):3425-36. doi: 10.1007/s00213-014-3590-6. Epub 2014 May 1. PubMed PMID: 24781519; PubMed Central PMCID: PMC4135005.

Jones MA, Amr S, Ferebee A, Huynh P, Rosenfeld JA, Miles MF, Davies AG, Korey CA, Warrick JM, Shiang R, Elsea SH, Girirajan S, Grotewiel M. Genetic studies in Drosophila and humans support a model for the concerted function of CISD2, PPT1 and CLN3 in disease. Biol Open. 2014 Apr 4;3(5):342-52. doi: 10.1242/bio.20147559. PubMed PMID: 24705017; PubMed Central PMCID: PMC4021356.

Jones BC, Huang X, Mailman RB, Lu L, Williams RW. The perplexing paradox of paraquat: the case for host-based susceptibility and postulated neurodegenerative effects. J Biochem Mol Toxicol. 2014 May;28(5):191-7. doi: 10.1002/jbt.21552. Epub 2014 Mar 5. Review. PubMed PMID: 24599642; PubMed Central PMCID: PMC4677573.

Jones BC, O'Callaghan JP, Lu L, Williams RW, Alam G, Miller DB. Genetic correlational analysis reveals no association between MPP+ and the severity of striatal dopaminergic damage following MPTP treatment in BXD mouse strains. Neurotoxicol Teratol. 2014 Sep-Oct;45:91-2. doi: 10.1016/j.ntt.2014.08.005. Epub 2014 Sep 2. PubMed PMID: 25192776.

Karkhanis AN, Locke JL, McCool BA, Weiner JL, Jones SR. Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood. Alcohol Clin Exp Res. 2014 Nov;38(11):2770-9. doi: 10.1111/acer.12555. PubMed PMID: 25421514; PubMed Central PMCID: PMC4519347. Keeley PW, Zhou C, Lu L, Williams RW, Melmed S, Reese BE. Pituitary tumor-transforming gene 1 regulates the patterning of retinal mosaics. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9295-300. doi: 10.1073/pnas.1323543111. Epub 2014 Jun 10. PubMed PMID: 24927528; PubMed Central PMCID: PMC4078852.

Keeley PW, Whitney IE, Madsen NR, St John AJ, Borhanian S, Leong SA, Williams RW, Reese BE. Independent genomic control of neuronal number across retinal cell types. Dev Cell. 2014 Jul 14;30(1):103-9. doi: 10.1016/j.devcel.2014.05.003. Epub 2014 Jun 19. PubMed PMID: 24954025; PubMed Central PMCID: PMC4101151.

Kroenke CD, Rohlfing T, Park B, Sullivan EV, Pfefferbaum A, Grant KA. Monkeys that voluntarily and chronically drink alcohol damage their brains: a longitudinal MRI study. Neuropsychopharmacology. 2014 Mar;39(4):823-30. doi: 10.1038/npp.2013.259. Epub 2013 Sep 27. PubMed PMID: 24077067; PubMed Central PMCID: PMC3924514.

Leeman RF, Beseler CL, Helms CM, Patock-Peckham JA, Wakeling VA, Kahler CW. A brief, critical review of research on impaired control over alcohol use and suggestions for future studies. Alcohol Clin Exp Res. 2014 Feb;38(2):301-8. doi: 10.1111/acer.12269. Epub 2013 Oct 7. Review. PubMed PMID: 24117468; PubMed Central PMCID: PMC3946792.

Lopez MF, Becker HC. Operant ethanol self-administration in ethanol dependent mice. Alcohol. 2014 May;48(3):295-9. doi: 10.1016/j.alcohol.2014.02.002. Epub 2014 Mar 13. Review. PubMed PMID: 24721194; PubMed Central PMCID: PMC4020177.

Lopez MF, Becker HC, Chandler LJ. Repeated episodes of chronic intermittent ethanol promote insensitivity to devaluation of the reinforcing effect of ethanol. Alcohol. 2014 Nov;48(7):639-45. doi: 10.1016/j.alcohol.2014.09.002. Epub 2014 Sep 6. PubMed PMID: 25266936; PubMed Central PMCID: PMC4250386.

Lopez MF, Laber K. Impact of social isolation and enriched environment during adolescence on voluntary ethanol intake and anxiety in C57BL/6J mice. Physiol Behav. 2014 Nov 8. pii: S0031-9384(14)00527-7. doi: 10.1016/j.physbeh.2014.11.012. [Epub ahead of print] PubMed PMID: 25446196.

Lotan A, Fenckova M, Bralten J, Alttoa A, Dixson L, Williams RW, van der Voet M. Neuroinformatic analyses of common and distinct genetic components associated with major neuropsychiatric disorders. Front Neurosci. 2014 Nov 6;8:331. doi: 10.3389/fnins.2014.00331. eCollection 2014. PubMed PMID: 25414627; PubMed Central PMCID: PMC4222236.

Maldonado-Devincci AM, Beattie MC, Morrow DH, McKinley RE, Cook JB, O'Buckley TK, Morrow AL. Reduction of circulating and selective limbic brain levels of (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) following forced swim stress in C57BL/6J mice. Psychopharmacology (Berl). 2014 Sep;231(17):3281-92. doi: 10.1007/s00213-014- 3552-z. Epub 2014 Apr 18. PubMed PMID: 24744202; PubMed Central PMCID: PMC4335654.

Maldonado-Devincci AM, Cook JB, O'Buckley TK, Morrow DH, McKinley RE, Lopez MF, Becker HC, Morrow AL. Chronic intermittent ethanol exposure and withdrawal alters (3α,5α)-3-hydroxy-pregnan-20-one immunostaining in cortical and limbic brain regions of C57BL/6J mice. Alcohol Clin Exp Res. 2014 Oct;38(10):2561-71. doi: 10.1111/acer.12530. Epub 2014 Oct 7. PubMed PMID: 25293837; PubMed Central PMCID: PMC4211975.

McCool BA, Chappell AM. Persistent enhancement of ethanol drinking following a monosodium glutamate- substitution procedure in C57BL6/J and DBA/2J mice. Alcohol. 2014 Feb;48(1):55-61. doi: 10.1016/j.alcohol.2013.10.008. Epub 2013 Nov 22. PubMed PMID: 24355071; PubMed Central PMCID: PMC3946935.

McCool BA, Christian DT, Fetzer JA, Chappell AM. Lateral/basolateral amygdala serotonin type-2 receptors modulate operant self-administration of a sweetened ethanol solution via inhibition of principal neuron activity. Front Integr Neurosci. 2014 Jan 30;8:5. doi: 10.3389/fnint.2014.00005. eCollection 2014. PubMed PMID: 24523680; PubMed Central PMCID: PMC3906593. McGuier NS, Padula AE, Lopez MF, Woodward JJ, Mulholland PJ. Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice. Alcohol. 2015 Feb;49(1):21-7. doi: 10.1016/j.alcohol.2014.07.017. Epub 2014 Nov 3. PubMed PMID: 25468278; PubMed Central PMCID: PMC4314373.

McLachlan SM, Aliesky H, Banuelos B, Magana J, Williams RW, Rapoport B. Immunoglobulin heavy chain variable region and major histocompatibility region genes are linked to induced graves' disease in females from two very large families of recombinant inbred mice. Endocrinology. 2014 Oct;155(10):4094-103. doi: 10.1210/en.2014-1388. Epub 2014 Jul 22. PubMed PMID: 25051451; PubMed Central PMCID: PMC4164918.

McLachlan SM, Hamidi S, Aliesky H, Williams RW, Rapoport B. Sex, genetics, and the control of thyroxine and thyrotropin in mice. Thyroid. 2014 Jul;24(7):1080-7. doi: 10.1089/thy.2014.0003. Epub 2014 May 22. PubMed PMID: 24564389; PubMed Central PMCID: PMC4080870.

Messaoudi I, Pasala S, Grant K. Could moderate alcohol intake be recommended to improve vaccine responses? Expert Rev Vaccines. 2014 Jul;13(7):817-9. doi:10.1586/14760584.2014.924405. Epub 2014 May 29. PubMed PMID: 24872009; PubMed Central PMCID: PMC4245072.

Miller OH, Yang L, Wang CC, Hargroder EA, Zhang Y, Delpire E, Hall BJ. GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine. Elife. 2014 Oct 23;3:e03581. doi: 10.7554/eLife.03581. PubMed PMID: 25340958; PubMed Central PMCID: PMC4270067.

Miranda-Dominguez O, Mills BD, Carpenter SD, Grant KA, Kroenke CD, Nigg JT, Fair DA. Connectotyping: model based fingerprinting of the functional connectome. PLoS One. 2014 Nov 11;9(11):e111048. doi: 10.1371/journal.pone.0111048. eCollection 2014. PubMed PMID: 25386919; PubMed Central PMCID: PMC4227655.

Miranda-Dominguez O, Mills BD, Grayson D, Woodall A, Grant KA, Kroenke CD, Fair DA. Bridging the gap between the human and macaque connectome: a quantitative comparison of global interspecies structure-function relationships and network topology. J Neurosci. 2014 Apr 16;34(16):5552-63. doi: 10.1523/JNEUROSCI.4229- 13.2014. PubMed PMID: 24741045; PubMed Central PMCID: PMC3988411.

Morrow AL. Special issue in memory of Robert H. Purdy. Psychopharmacology (Berl). 2014 Sep;231(17):3241-2. doi: 10.1007/s00213-014-3585-3. Epub 2014 Apr 22. PubMed PMID: 24752660.

Muldoon PP, Jackson KJ, Perez E, Harenza JL, Molas S, Rais B, Anwar H, Zaveri NT, Maldonado R, Maskos U, McIntosh JM, Dierssen M, Miles MF, Chen X, De Biasi M, Damaj MI. The α3β4* nicotinic ACh receptor subtype mediates physical dependence to morphine: mouse and human studies. Br J Pharmacol. 2014 Aug;171(16):3845-57. doi: 10.1111/bph.12741. PubMed PMID: 24750073; PubMed Central PMCID: PMC4128047.

Nesic J, Duka T. Effects of stress and dietary tryptophan enhancement on craving for alcohol in binge and non-binge heavy drinkers. Behav Pharmacol. 2014 Sep;25(5-6):503-17. doi: 10.1097/FBP.0000000000000067. PubMed PMID: 25036731, PubMed Central PMCID: PMC4141218.

Pandey AK, Lu L, Wang X, Homayouni R, Williams RW. Functionally enigmatic genes: a case study of the brain ignorome. PLoS One. 2014 Feb 11;9(2):e88889. doi: 10.1371/journal.pone.0088889. eCollection 2014. PubMed PMID: 24523945; PubMed Central PMCID: PMC3921226.

Pandey AK, Williams RW. Genetics of gene expression in CNS. Int Rev Neurobiol. 2014;116:195-231. doi: 10.1016/B978-0-12-801105-8.00008-4. PubMed PMID: 25172476; PubMed Central PMCID: PMC4258695.

Piza-Palma C, Barfield ET, Brown JA, Hubka JC, Lusk C, Schonhar CA, Sweat SC, Grisel JE. Oral self-administration of EtOH: sex-dependent modulation by running wheel access in C57BL/6J mice. Alcohol Clin Exp Res. 2014 Sep;38(9):2387-95. doi:10.1111/acer.12519. PubMed PMID: 25257288; PubMed Central PMCID: PMC5495182.

Porcu P, Morrow AL. Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies. Psychopharmacology (Berl). 2014 Sep;231(17):3257-72. doi: 10.1007/s00213-014- 3564-8. Epub 2014 Apr 26. PubMed PMID: 24770626; PubMed Central PMCID: PMC4135033. Porcu P, Locci A, Santoru F, Berretti R, Morrow AL, Concas A. Failure of acute ethanol administration to alter cerebrocortical and hippocampal allopregnanolone levels in C57BL/6J and DBA/2J mice. Alcohol Clin Exp Res. 2014 Apr;38(4):948-58. doi: 10.1111/acer.12329. Epub 2014 Jan 15. PubMed PMID: 24428156; PubMed Central PMCID: PMC4142143.

Shin DL, Pandey AK, Ziebarth JD, Mulligan MK, Williams RW, Geffers R, Hatesuer B, Schughart K, Wilk E. Segregation of a spontaneous Klrd1 (CD94) mutation in DBA/2 mouse substrains. G3 (Bethesda). 2014 Dec 17;5(2):235-9. doi: 10.1534/g3.114.015164. PubMed PMID: 25520036; PubMed Central PMCID: PMC4321031.

Stephens MC, McCaul ME, Wand GS. (2014) The potential role of glucocorticoids and the HPA axis in alcohol dependence. In A Noronha, C Cui, A Harris and J Crabbe (Eds.), Neurobiology of Alcohol Dependence (pp. 429- 450). London: Elsevier.

Uys JD, Mulholland PJ, Townsend DM. Glutathione and redox signaling in substance abuse. Biomed Pharmacother. 2014 Jul;68(6):799-807. doi: 10.1016/j.biopha.2014.06.001. Epub 2014 Jun 24. Review. PubMed PMID: 25027386; PubMed Central PMCID: PMC4455547.

Wang L, Lu W, Zhang L, Huang Y, Scheib R, Liu X, Myers L, Lu L, Farber CR, Liu G, Wang CY, Deng H, Williams RW, Wang Y, Gu W, Jiao Y. Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men. PLoS One. 2014 Jan 8;9(1):e84485. doi: 10.1371/journal.pone.0084485. eCollection 2014. PubMed PMID: 24416236; PubMed Central PMCID: PMC3885592.

Williams MA, Li C, Kash TL, Matthews RT, Winder DG. Excitatory drive onto dopaminergic neurons in the rostral linear nucleus is enhanced by norepinephrine in an α1 adrenergic receptor-dependent manner. Neuropharmacology. 2014 Nov;86:116-24. doi: 10.1016/j.neuropharm.2014.07.001. Epub 2014 Jul 10. PubMed PMID: 25018040; PubMed Central PMCID: PMC4188726.a>

Ye R, Carneiro AM, Airey D, Sanders-Bush E, Williams RW, Lu L, Wang J, Zhang B, Blakely RD. Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice. Genes Brain Behav. 2014 Mar;13(3):247-60. doi: 10.1111/gbb.12092. Epub 2013 Oct 31. PubMed PMID: 24102824; PubMed Central PMCID: PMC3979832.

Yorgason JT, Ferris MJ, Steffensen SC, Jones SR. Frequency-dependent effects of ethanol on dopamine release in the nucleus accumbens. Alcohol Clin Exp Res. 2014 Feb;38(2):438-47. doi: 10.1111/acer.12287. Epub 2013 Oct 11. PubMed PMID: 24117706; PubMed Central PMCID: PMC4085573.