sensfeel™ Increases man’s power of physical attraction
sensfeel™ is an active designed to enhance man’s appeal, by increasing the synthesis of his own pheromones
What are pheromones? How does sensfeelTM work? Pheromones are natural, odourless and sensfeelTM modulates the pheromones production consciously undetectable substances, which by the synergistic action of its components: trigger a deep sexual response in the brain of Forskolin those who come into contact with them. Diterpene obtained from makandi root (Coleus The pheromone related to human sexual forskohlii). attraction is androstadienone. Increases the expression of the enzyme The production and secretion of pheromones 3ß-HSD to produce more androstadienone. are natural processes regulated by hormones and stimuli from nervous system, which arrive Theaflavins to cells of apocrine glands and sebocytes of Polyphenols obtained from black tea leaves sebaceous glands. (Camellia sinensis). Reduce 5α-reductase activity to decrease androstadienone metabolization and cause its accumulation.
3ß-HSD 5α-reductase 3α-HSD
Androstadienol Androstadienone Androstenone Androstenol FORSKOLIN +=THEAFLAVINS Activation Inhibition sensfeel™
sensfeel™ is a natural green alternative to enhance the production of a male pheromone called androstadienone, with the aim of increasing the power of attraction SENSORIAL
In vitro efficacy
Development of an innovative cellular model Boosting effect of androstadienone production
The creation of a suitable cellular model able The complementary actions of forskolin and to produce pheromones was necessary to theaflavins lead to a boosting synergistic effect. evaluate sensfeel™ in vitro efficacy. sensfeel™ doubles the production of Progenitor keratinocytes, which can androstadienone (105%) at a concentration of differentiate to sebocytes under certain 1.2%. conditions, were selected. SYNERGISTIC EFFECT Originated sebocytes were identified, 205% 250 characterized and they showed their ability to 200 141% produce pheromones, especially 100% 111% 150 androstadienone. 100 50 0 ACTIVE FK TF FK/TF C3
INCREASE VS. CONTROL CONTROL (FORSKOLIN) (THEAFLAVINS) (sensfeel™ 1.2%)
The amount of pheromone increases in parallel to the concentration of sensfeel™,
SEBOCYTES (7 DAYS) SEBOCYTES reaching three times the control result at the maximum dosage (5%).
DOSE EFFECT 269% 300 223% 205% 250 200 137% 150 100% 100 50 0 SEBOCYTES (15 DAYS) SEBOCYTES INCREASE VS. CONTROL ACTIVE FK/TF C1 FK/TF C3 FK/TF C4 FK/TF C5 CONTROL (sensfeel™ (sensfeel™ (sensfeel™ (sensfeel™ 0.25%) 1.2%) 2.5%) 5%)
Representative images obtained by immunofluorescence. They show HPEK cells differentiated to keratinocytes and sebocytes at 7 and 15 days. The red dye represents polar lipids (phospholipids), the green With sensfeel™, feel the power dye non-polar or neutral lipids (triglycerides and waxes), and of attraction the blue dye nucleus.