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Schizophrenia Bipolar, acute mania Bipolar, acute mixed Bipolar, maintenance MDD GAD Social Anxiety D/O Panic D/O PTSD PsychiatricOCD Indications PMDD Bulimia nervosa Insomnia EPS ADHD TCA=tricyclic antidepressant MAO-I=monoamine oxidase inhibitor MDD=major depressive d/o GAD=generalized anxiety d/o OCD=obsessive compulsive d/o PMDD=pre-menstrual dysphoric d/o EPS=extrapyramidal symptoms ADHD=attention deficit hy *for treatment-resistant schizo **includes ***includes amantadine, benztro ªBHCS non-formular conventional APs XXXXXX p X XXXXXXaripiprazole X henelzine, tran ☼ X X XXXX Updated December 13, 2005 XXclozapin XXe* All conventional antipsychotics (except pimozide) below Oral Medications Used in Adult Psychiatry ♦ ☼ olanzapine Lorazepam, oxazepam, alprazolam See y medication quetiapine y lc risperidone p yp ♣ hrenia onl romine, isocarboxazid All tricyclic antidepressants are indicated for ziprasidone p ine, bi carbamazepine p y divalproex Na iriden, di ; also indicated for reduction in risk of recurrent suicidal behaviors in schizo Chlorpromazine gabapentinª lamotrigine p henh lithium Temazepam, triazolam, flurazepam y dramine, trihex oxcarbazepineª Diazepam topiramateª is also indicated for treatment of TCAs , and HaloperidolPimozide citalopram and yp chlordiazepoxide Diazepam XXX XXXXXXXXescitalopram henid ♣ below chlordiazepoxide are indicated for See fluoxetine XX X yl is only Clonazepam fluvoxamine is also indicated for XXX X is indicated for relief of paroxetine Depression XXXX indicated for XXX sertraline X XX bupropion are indicated for XX is indicated for Schizophrenia/management of manifestations of Psychotic D/Os duloxetineª are indicated for , and , except MAO-Is** A Tourette's D/O. cute mania associated with Bipolar D/O. estazolam mirtazapine Tourette's D/O. trazodone clomipramine p venlafaxine Acute anixety "Anxiety D/O or short-term relief of symptoms of anxiety." hrenia or schizoaffective d/o Panic D/O. benzodiazepines are indicated for A cute alcohol withdrawal. buspirone PTSD=post-traumatic stress d/o chloral hydrate below , which is only approved for ♦ peractivity d/o See zaleplon . zolpidem antiparkinsonians*** Insomnia XXX amphetamine salts XR atomoxetineª d-methylphenidate XRª only. X XXX OCD. .

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AMANTADIP\Dle: on Nemolebtic-II[WDUCED CATALEPSY UV the RAT
J. Fac. Plmnz. Istanbul lstanbul Ecz. Fak. Mec. 29, 1 (1993) 29, 1 (1993) THE EFFECT OF CYPROHEPT~~AWEb AMANTADIP\dlE: ON NEmOLEBTIC-II[WDUCED CATALEPSY UV THE RAT SUMMARY Catalepsy is not a unitary phenomenon. With respect to biochemical mechanisms and neurotransmitter sytems, the origin of this behavioural response varies according to different substances which cause catalepsy. For example, the catdeptogenic effect of ne- uroleptics has been related to the blockage of striatal doparnine receptors. Neurophysio- logical and biochemical data have shown that a mechanism caused by gama-aminobuty- ric acid and serotonin have been effective in the proper functioning of the dopaminergic nigrosbriatal tract. We have studied the effects of cyproheptadine, a serotonin antagonist, and of amantadin which is used in the treatment of Parkinson syndrome on the catalepsy indu- ced by trifluoperazine, a phenothiazin compound, and pimozid, a drug used as a neuro- leptic. It was observed that when rats were pretreated with cyproheptadine as well as amantadiie, the catalepsy induced by the above neuroleptic drugs was attenuated. The results of our study show that substances which have an effect on the seroto- nergic and dopaminergic systems also play a role on cases of catalepsy induced by the neuroleptic drugs mentioned above. (*) Faculty of Pharmacy, Depament of Pharmacology, University of Istanbul, 31152, Istanbul, Turkey Katalepsi bir tek nedene bagh OWortaya qllian bit durum degildir. Biyokimya- sal ve norotransmitter sistemler agsmdan bu davran~glnsebebi, katalepsi olughYan qe- gitli maddeler iqin fad&&. Omegin noroleptiklerin kataleptojenik etkisi striatal dopa- min reseptorlerinin blokaj~nabajjlanmqtx. Niirofizyolojik ve biyokimyasal veriler do- pamine jik nigro-striatal sistemin duzenli $&$masmda gma-aminobutirik asid ve sero- tonin'e bagh olan bir mekanizmmn etkili oldugunu gostermigtir.
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65 © Elsevier/North-Holland Biomedical Press MONOAMINE REPLACEMENT AFTER RESERPINE: CATECHOLAMINERGIC AGONISTS RESTORE MOTOR AC
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