Article Topical Emulsion Containing Lavandula stoechas Essential Oil as a Therapeutic Agent for Cutaneous Wound Healing Mohamed Nadjib Boukhatem 1,2,* , Henni Chader 3,4, Aicha Houche 1, Faiza Oudjida 5, Fatma Benkebaili 1 and Yahia Hakim 6 1 Department of Biology, Faculty of Life and Natural Sciences, University Blida 1, Blida 09000, Algeria;
[email protected] (A.H.);
[email protected] (F.B.) 2 Laboratoire Ethnobotanique et Substances Naturelles, Ecole Normale Supérieure, Kouba, Alger 16047, Algeria 3 Laboratoire Pharmaco-Toxicologie, Laboratoire National de Contrôle des Produits Pharmaceutiques (LNCPP), Dély Brahim, Alger 16047, Algeria;
[email protected] 4 Faculté de Médecine, Université Ben Youcef Ben Khedda, Alger I, Alger 16000, Algeria 5 Laboratoire Anatomie Pathologique, Centre Hospitalo-Universitaire de Beni Messous, Alger 16206, Algeria;
[email protected] 6 Extral-Bio Company, Chiffa, Blida 09000, Algeria;
[email protected] * Correspondence:
[email protected]; Tel.: +213-664983174 Abstract: Background and objectives: The present research was designed to evaluate the chemical composition of Lavandula stoechas essential oil (EOLS) as well as the in vivo wound-healing property. The chemical composition of EOLS was identified by gas chromatography mass spectrometry. Nine- teen compounds of EOLS were reported. Linalool was identified as the major chemical compound Citation: Boukhatem, M.N.; (24.87%), followed by linalyl acetate (19.10%). EOLS showed a high content of oxygenated com- Chader, H.; Houche, A.; Oudjida, F.; pounds (63.54%). In vivo wound healing activity of the topical cream prepared from EOLS (0.5% w/w) Benkebaili, F.; Hakim, Y. Topical was assessed using a circular excision wound model.