The Miracle of Stem Cells ) How Adult Stem Cells are Transforming Medicine Roger J. Howe, PhD, Maynard A. Howe, PhD, Nikolai I. Tankovich, MD, PhD, David A. Howe, MD, with James R. Tager Copyright © 2011 by Stemedica Cell Technologies, Inc. Distributed by Changewell, Inc. Printed in the United States of America. All rights reserved. This book, or any parts thereof, may not be used or reproduced in any manner without written permission. For more information: Changewell, Inc., P.O. Box 7303, Rancho Sante Fe, CA 92067 www.changewell.com
[email protected] T: 858-756-1491 F: 858-756-3467 ISBN 10: 0-9716250-9-3 ISBN 13: 9780971625099 Front cover: Image of cell is courtesy of Stemedica, Dr. Yuri Kudinov (MD, PhD). Design was done by Nancy Van Allen. Neural stem cell that was stained with membrane dye Dil and nuclear dye DAPI. Back cover images from left to right: Retinal Pigement Epithelial (RPE) cells image: Reprinted by permission from Macmillan Publishers Ltd: Nature Biotechnology, Osakada, F., Ikeda, H., Mandai, M., Wataya, T., Watanabe, K., Yoshimura, N., ... Takahashi, M. Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells, 26(2), 215-224, copy- right (2008). Cardiomyocyte image: Copyright (2003) National Academy of Sciences, U.S.A. Urbanek, K., Quaini, F., Giordano, T., Torella, D., Castaldo, C., Nadal-Ginard, B., ... Anversa, P. (2003). Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America, 100(18), 10440-10445. All other images on the backcover are courtesy of Stemedica, Dr.