Medicinal Plants & Their Importance
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
On Adulteration of Hydrastis Canadensis Root and Rhizome by Michael Tims, Phd Maryland University of Integrative Health, 7750 Montpelier Road, Laurel, MD 20723
on Adulteration of Hydrastis canadensis root and rhizome By Michael Tims, PhD Maryland University of Integrative Health, 7750 Montpelier Road, Laurel, MD 20723 Correspondence: e-mail Keywords: Hydrastis canadensis, goldenseal root, adulterant, adulteration Goal: The goal of this bulletin is to provide information and/or updates on issues regarding adulteration of goldenseal (Hydrastis canadensis) root to the international herbal industry and extended natural products community in general. It is intended to present the available data on occurrence of adulteration, the market situa- tion, and consequences for the consumer and the industry. 1 General Information 1.1 Common name: Goldenseal1,2 1.2 Other common names: English: Yellow root, yellow puccoon, ground raspberry, wild curcuma*, Indian dye, eye root, eye balm, Indian paint, jaundice root, Warnera3,4 French: Hydraste du Canada, hydraste, fard inolien, framboise de terre, sceau d’or5 German: Goldsiegelwurzel, Kanadische Gelbwurz, Kanadische Orangenwurzel5 Italian: Idraste, radice gialla6 Goldenseal Hydrastis canadensis Spanish: Hidrastis, hidrastis de Canadá, raíz de oro, scello de Photo ©2016 Steven Foster oro5 1.3 Accepted Latin binomial: Hydrastis canadensis7,8 1.4 Botanical family: Ranunculaceae 1.5 Plant part and form: Whole fresh or dry roots and rhizomes, powdered dry roots and rhizomes, hydroalcoholic and glycerin-water extracts and powdered dry extracts.9,10 Dried whole or powdered roots and rhizomes complying with the United States Pharmacopeia (USP) are required to contain -
The First Comprehensive Phylogeny of Coptis (Ranunculaceae) and Its Implications for Character Evolution and Classification
RESEARCH ARTICLE The First Comprehensive Phylogeny of Coptis (Ranunculaceae) and Its Implications for Character Evolution and Classification Kun-Li Xiang1,2, Sheng-Dan Wu3, Sheng-Xian Yu1, Yang Liu4, Florian Jabbour5, Andrey S. Erst6,7, Liang Zhao8, Wei Wang1*, Zhi-Duan Chen1 1 State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China, 2 University of Chinese Academy of Sciences, Beijing, 100049, China, 3 College of Life Sciences, Shanxi Normal University, Linfen, 041004, China, 4 Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, Connecticut, 06269–3043, United States of America, 5 Muséum national d’Histoire naturelle, Institut de Systématique, Evolution, Biodiversité, UMR 7205 ISYEB MNHN/CNRS/UPMC/EPHE, Sorbonne Universités, Paris, 75005, France, 6 Central Siberian Botanical Garden of the Siberian Branch of Russian Academy of Sciences, Zolotodolinskaya str. 101, Novosibirsk, 630090, Russia, 7 Laboratory of Systematics and Phylogeny of Plants, National Research Tomsk State University, prospekt Lenina 36, Tomsk, 634050, Russia, 8 College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, 712100, China * [email protected] OPEN ACCESS Citation: Xiang K-L, Wu S-D, Yu S-X, Liu Y, Jabbour F, Erst AS, et al. (2016) The First Comprehensive Abstract Phylogeny of Coptis (Ranunculaceae) and Its Implications for Character Evolution and Coptis (Ranunculaceae) contains 15 species and is one of the pharmaceutically most Classification. PLoS ONE 11(4): e0153127. important plant genera in eastern Asia. Understanding of the evolution of morphological doi:10.1371/journal.pone.0153127 characters and phylogenetic relationships within the genus is very limited. -
Utility of a Phylogenetic Perspective in Structural Analysis of CYP72A Enzymes from Flowering Plants
RESEARCH ARTICLE Utility of a Phylogenetic Perspective in Structural Analysis of CYP72A Enzymes from Flowering Plants Wil Prall, Oliver Hendy, Leeann E. Thornton* Department of Biology, The College of New Jersey, Ewing, New Jersey, United States of America * [email protected] a11111 Abstract Plant adaptation to external pressures depends on functional diversity in cytochrome P450 (CYP) enzymes. CYPs contain structural domains necessary for the characteristic P450 fold that allows monooxygenation, but they also have great variation in substrate binding affinity. Plant genomes typically contain hundreds of CYPs that contribute to essential func- tions and species-specific metabolism. The CYP72A subfamily is conserved in angio- OPEN ACCESS sperms but its contribution to physiological functions is largely unknown. With genomic Citation: Prall W, Hendy O, Thornton LE (2016) information available for many plants, a focused analysis of CYP subfamily diversity is Utility of a Phylogenetic Perspective in Structural Analysis of CYP72A Enzymes from Flowering important to understand the contributions of these enzymes to plant evolution. This study Plants. PLoS ONE 11(9): e0163024. doi:10.1371/ examines the extent to which independent gene duplication and evolution have contributed journal.pone.0163024 to structural diversification of CYP72A enzymes in different plant lineages. CYP72A genes Editor: BjoÈrn Hamberger, Michigan State are prevalent across angiosperms, but the number of genes within each genome varies University, UNITED STATES greatly. The prevalence of CYP72As suggest that the last common ancestor of flowering Received: May 12, 2016 plants contained a CYP72A sequence, but gene duplication and retention has varied Accepted: September 1, 2016 greatly for this CYP subfamily. -
Alkaloids – Secrets of Life
ALKALOIDS – SECRETS OF LIFE ALKALOID CHEMISTRY, BIOLOGICAL SIGNIFICANCE, APPLICATIONS AND ECOLOGICAL ROLE This page intentionally left blank ALKALOIDS – SECRETS OF LIFE ALKALOID CHEMISTRY, BIOLOGICAL SIGNIFICANCE, APPLICATIONS AND ECOLOGICAL ROLE Tadeusz Aniszewski Associate Professor in Applied Botany Senior Lecturer Research and Teaching Laboratory of Applied Botany Faculty of Biosciences University of Joensuu Joensuu Finland Amsterdam • Boston • Heidelberg • London • New York • Oxford • Paris San Diego • San Francisco • Singapore • Sydney • Tokyo Elsevier Radarweg 29, PO Box 211, 1000 AE Amsterdam, The Netherlands The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, UK First edition 2007 Copyright © 2007 Elsevier B.V. All rights reserved No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email: [email protected]. Alternatively you can submit your request online by visiting the Elsevier web site at http://elsevier.com/locate/permissions, and selecting Obtaining permission to use Elsevier material Notice No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation -
Botanikos Sodo Augalų Sąvadas
ŠIAULI Ų UNIVERSITETAS Asta Klimien ė, Rimanta Vainorien ė, Roberta Dubosait ė-Lepeškevi čė , Aldona Grišait ė, Vaidas Juknevi čius BOTANIKOS SODO AUGAL Ų S ĄVADAS 4 Leidinyje apibendrinama informacija apie Šiauli ų universiteto Botanikos sode sukauptas augal ų takson ų ir veisli ų kolekcijas. Augal ų s ąvadas sudarytas naudojantis A. L. Tachtadžjano sistema. Lietuviški ir lotyniški augal ų vardai apib ūdinti remiantis literat ūros s ąraše pateiktais šaltiniais. Lietuviški augal ų vardai pateikti remiantis Valstybin ės lietuvi ų kalbos komisijos patvirtintu lietuvišk ų augal ų vard ų s ąrašu. Sąvade šeimos, augal ų taksonai ir veisl ės išd ėstyti alfabeto tvarka. Viršelyje melsvasis gencijonas ( Gentiana cruciata L.). R ūšis įtraukta į Lietuvos Raudonosios knygos s ąrašus. Nuotraukos autorius fotografas Romualdas Struoga. 2 TURINYS PRATARM Ė .....................................................................................................................................4 1. EQUISETOPHYTA ......................................................................................................................6 EQUISETOPSIDA ...............................................................................................................6 2. POLYPODIOPHYTA …………………………………………………………………………. 6 POLYPODIOPSIDA …………………………………………...………………………… 6 3. PINOPHYTA ................................................................................................................................7 GINKGOOPSIDA ................................................................................................................7 -
Occurrence and Function of Natural Products in Plants – Michael Wink
PHYTOCHEMISTRY AND PHARMACOGNOSY – Occurrence and Function of Natural Products in Plants – Michael Wink OCCURRENCE AND FUNCTION OF NATURAL PRODUCTS IN PLANTS Michael Wink Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, INF 364, 69120 Heidelberg, Germany Keywords: Secondary metabolites, ecological functions, defense compounds, signal compounds, evolution, chemotaxonomy, pharmacology, toxicology, endophytic fungi, horizontal gene transfer, transport, storage Contents 1. Classes and Numbers of Secondary Metabolites (SM) 2. Occurrence and Properties of Major Groups of SM 3. Physiology of Secondary Metabolism: Biosynthesis, Transport and Storage of SM 4. Ecological Roles of SM 5. Molecular Modes of Action of SM 6. Chemosystematics of Plants and Distribution Patterns of SM 7. Origins and Evolution of Plant Secondary Metabolism 8. Conclusions Glossary Bibliography Biographical sketch Summary Secondary metabolites (SM) occur in plants in a high structural diversity. A typical feature of secondary metabolites is their storage as complex mixtures in relatively high concentrations, sometimes in organs which do not produce them. Some SM are stored as inactive “prodrugs” that are enzymatically activated in case of danger (wounding, infection). Biochemical and physiological features of secondary metabolism are strongly correlated with its function: SM are not useless waste products but important means of plants for defense against herbivores, microbes (bacteria, fungi) and viruses. Some SM also functions as signal molecules to attract pollinating arthropods or seed- dispersing animals. Land plants have evolved SM with a wide repertoire of biochemical and pharmacologicalUNESCO properties. Many –SM inEOLSSteract with proteins, DNA/RNA and/or biomembranes. Some of the interactions with molecular targets are highly specific, others have pleiotropicSAMPLE properties. All plants CHAPTERSproduce secondary metabolites. -
Considérations Sur L'histoire Naturelle Des Ranunculales
Considérations sur l’histoire naturelle des Ranunculales Laetitia Carrive To cite this version: Laetitia Carrive. Considérations sur l’histoire naturelle des Ranunculales. Botanique. Université Paris-Saclay, 2019. Français. NNT : 2019SACLS177. tel-02276988 HAL Id: tel-02276988 https://tel.archives-ouvertes.fr/tel-02276988 Submitted on 3 Sep 2019 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Considérations sur l’histoire naturelle des Ranunculales 2019SACLS177 Thèse de doctorat de l'Université Paris-Saclay : préparée à l’Université Paris-Sud NNT École doctorale n°567 : Sciences du végétal, du gène à l'écosystème (SDV) Spécialité de doctorat : Biologie Thèse présentée et soutenue à Orsay, le 05 juillet 2019, par Laetitia Carrive Composition du Jury : Catherine Damerval Directrice de recherche, CNRS (– UMR 320 GQE) Présidente du jury Julien Bachelier Professeur, Freie Universität Berlin (– Institute of Biology) Rapporteur Thomas Haevermans Maître de conférences, MNHN (– UMR 7205 ISYEB) Rapporteur Jean-Yves Dubuisson Professeur, SU (–UMR 7205 ISYEB) Examinateur Sophie Nadot Professeure, U-PSud (– UMR 8079 ESE) Directrice de thèse « Le commencement sera d’admirer tout, même les choses les plus communes. Le milieu, d’écrire ce que l’on a bien vu et ce qui est d’utilité. -
Piper Nigrum CYP719A37 Catalyzes the Decisive Methylenedioxy Bridge Formation in Piperine Biosynthesis
plants Article Piper nigrum CYP719A37 Catalyzes the Decisive Methylenedioxy Bridge Formation in Piperine Biosynthesis Arianne Schnabel 1 , Fernando Cotinguiba 2 , Benedikt Athmer 1 and Thomas Vogt 1,* 1 Leibniz Institute of Plant Biochemistry, Department Cell and Metabolic Biology, Weinberg 3, D-06120 Halle (Saale), Germany; [email protected] (A.S.); [email protected] (B.A.) 2 Instituto de Pesquisas de Produtos Naturais (IPPN), Universidade Federal do Rio de Janeiro (UFRJ), Avenida Carlos Chagas Filho, 373, 21941-902 Rio de Janeiro/RJ, Brazil; [email protected] * Correspondence: [email protected] Abstract: Black pepper (Piper nigrum) is among the world’s most popular spices. Its pungent principle, piperine, has already been identified 200 years ago, yet the biosynthesis of piperine in black pepper remains largely enigmatic. In this report we analyzed the characteristic methylenedioxy bridge formation of the aromatic part of piperine by a combination of RNA-sequencing, functional expression in yeast, and LC-MS based analysis of substrate and product profiles. We identified a single cytochrome P450 transcript, specifically expressed in black pepper immature fruits. The corresponding gene was functionally expressed in yeast (Saccharomyces cerevisiae) and characterized for substrate specificity with a series of putative aromatic precursors with an aromatic vanilloid structure. Methylenedioxy bridge formation was only detected when feruperic acid (5-(4-hydroxy- 3-methoxyphenyl)-2,4-pentadienoic acid) was used as a substrate, and the corresponding product was identified as piperic acid. Two alternative precursors, ferulic acid and feruperine, were not accepted. Our data provide experimental evidence that formation of the piperine methylenedioxy bridge takes place in young black pepper fruits after a currently hypothetical chain elongation of ferulic acid and before the formation of the amide bond. -
Title Phylogenetic Distribution of Lignan Producing Plants
Title Phylogenetic Distribution of Lignan Producing Plants Author(s) UMEZAWA, Toshiaki Wood research : bulletin of the Wood Research Institute Kyoto Citation University (2003), 90: 27-110 Issue Date 2003-09-30 URL http://hdl.handle.net/2433/53098 Right Type Departmental Bulletin Paper Textversion publisher Kyoto University Note Phylogenetic Distribution of Lignan Producing Plants T oshiaki U MEZAWA *1 (Received May 31, 2003) Keywords: biosynthesis, evolution, lignans, phylogenetic distribution herein the author presents the complete and detailed list of Abstract phylogenetic distribution oflignan producing plant species Lignans are phenylpropanoid dimers, where the phenyl in relation to 66 typical lignans belonging to the 12 lignan propane units are linked by the central carbon (Cs) oftheir subgroups. 7 side chains. The chemical structures of lignans vary In the previous review ), 66 typicallignans (Fig. 1) were substantially in basic carbon frameworks, as do their chosen based on a database search. Briefly, 308 typical 2 oxidation levels and substitution patterns. In addition, lignans listed by Ayres and Loike ) was subjected to a lignans show considerable diversity in terms of enanti database search [SciFinder Scholar; database, CAPLUS; omeric compositions, biosynthesis, and phylogenetic keywords, "the name ofeach lignan (e.g. pinoresinol)" and distribution. In this paper, the phylogenetic distribution "isolation"], and lignans which appeared in more than 10 of plants producing more than 70 typical lignans with a papers were chosen, giving rise to the 66 lignans. As variety of chemical structures are listed based on a data shown in Fig. 1, the 66 lignans were classified into the 12 base search. subgroups taki~g the possible biosynthetic pathways into account. -
The First Comprehensive Phylogeny of Coptis
The First Comprehensive Phylogeny of Coptis (Ranunculaceae) and Its Implications for Character Evolution and Classification Kun-Li Xiang, Sheng-Dan Wu, Sheng-Xian Yu, Yang Liu, Florian Jabbour, Andrey S. Erst, Liang Zhao, Wei Wang, Zhi-Duan Chen To cite this version: Kun-Li Xiang, Sheng-Dan Wu, Sheng-Xian Yu, Yang Liu, Florian Jabbour, et al.. The First Com- prehensive Phylogeny of Coptis (Ranunculaceae) and Its Implications for Character Evolution and Classification. PLoS ONE, Public Library of Science, 2016, 11 (4), pp.e0153127. 10.1371/jour- nal.pone.0153127. hal-01310776 HAL Id: hal-01310776 https://hal.sorbonne-universite.fr/hal-01310776 Submitted on 3 May 2016 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Distributed under a Creative Commons Attribution| 4.0 International License RESEARCH ARTICLE The First Comprehensive Phylogeny of Coptis (Ranunculaceae) and Its Implications for Character Evolution and Classification Kun-Li Xiang1,2, Sheng-Dan Wu3, Sheng-Xian Yu1, Yang Liu4, Florian Jabbour5, Andrey S. Erst6,7, Liang Zhao8, Wei Wang1*, Zhi-Duan -
Analysis of the Coptis Chinensis Genome Reveals the Diversification
ARTICLE https://doi.org/10.1038/s41467-021-23611-0 OPEN Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids ✉ Yifei Liu 1,9 , Bo Wang2,9, Shaohua Shu3,9, Zheng Li4,9, Chi Song5, Di Liu1, Yan Niu5, Jinxin Liu3, Jingjing Zhang1, Heping Liu3, Zhigang Hu1, Bisheng Huang1, Xiuyu Liu6, Wei Liu1, Liping Jiang1, Mohammad Murtaza Alami3, Yuxin Zhou2, Yutao Ma3, Xiangxiang He5, Yicheng Yang5, Tianyuan Zhang5, ✉ ✉ ✉ Hui Hu7, Michael S. Barker 4, Shilin Chen8 , Xuekui Wang3 & Jing Nie2 1234567890():,; Chinese goldthread (Coptis chinensis Franch.), a member of the Ranunculales, represents an important early-diverging eudicot lineage with diverse medicinal applications. Here, we present a high-quality chromosome-scale genome assembly and annotation of C. chinensis. Phylogenetic and comparative genomic analyses reveal the phylogenetic placement of this species and identify a single round of ancient whole-genome duplication (WGD) shared by the Ranunculaceae. We characterize genes involved in the biosynthesis of protoberberine- type alkaloids in C. chinensis. In particular, local genomic tandem duplications contribute to member amplification of a Ranunculales clade-specific gene family of the cytochrome P450 (CYP) 719. The functional versatility of a key CYP719 gene that encodes the (S)-canadine synthase enzyme involved in the berberine biosynthesis pathway may play critical roles in the diversification of other berberine-related alkaloids in C. chinensis. Our study provides insights into the genomic landscape of early-diverging eudicots and provides a valuable model gen- ome for genetic and applied studies of Ranunculales. 1 College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China. 2 Hubei Institute for Drug Control, Wuhan, China. -
Alkaloid Chemistry in Biosynthesis, Models and Other Methodological Considerations and Basic Techniques Used
Elsevier AMS Prelims-N52736 Job code: ASLA 17-2-2007 12:35p.m. Page:xi Trimsize:165×240MM List of Figures 1 Contemporary scheme of morphine. 2 2 Some alkaloids isolated by pharmaceutists Pierre Joseph Pelletier and Joseph Beinamé Caventou during 1817–1821. 3 3 Schemes of taxol, vinblastine, vincristine and vincamine 5 4 An example of a true alkaloid 11 5 An example of protoalkaloids 11 6 An example of a pseudoalkaloid 12 7 The raw extraction of quinolizidine alkaloids 13 8 l-tryptophan with its aromatic side chain 15 9 The devil’s-pepper genus, Rauwolfia serpentina 15 10 l-phenylalanine is a precursor 17 11 l-ornithine is an important precursor 19 12 l-tyrosine, with its aromatic side chain 19 13 l-anthranilic acid is a precursor 23 14 l-histidine is a precursor 24 15 l-ornithine and l-nicotinic acids are precursors 26 16 l-lysine is a precursor 31 17 (a) Structure of seed testa of the Washington lupine (b) Alkaloidal Lupinus polyphyllus Lindl. 32 18 Jervine, cyclopamine and protoveratrine structures. 49 19 Basic alkaloids of mushrooms. 55 20 Ergotamine and LSD 56 21 Secondary metabolism blocks 65 22 Pyruvate derivation and acetyl CoA synthesis 66 23 General scheme of alkaloid synthesis 68 24 l-lysine-derived nuclei 69 25 Nuclei and skeletons of izidine alkaloids 70 26 The source and forms of the pyrrolidine ring 70 27 l-histidine and the nuclei of imidazole and manzamine alkaloids. 70 28 The nuclei produced by anthranilic acid in alkaloids 71 29 The nucleus of alkaloids derived from nicotinic acid 72 30 l-phenylanine-derived nuclei in alkaloid biosynthesis 72 31 Nuclei supplied to alkaloids by l-tyrosine in the synthesizing process 73 32 The l-tryptophan-supplied nucleus during synthesis 74 33 Synthesis of alkaloids from ornithine 75 34 Synthesis pathway of the pyrrolizidine alkaloids 76 35 Synthesis of hordeine and mescaline 77 Font Used:Times Margins:Top:18mm Gutter:20mm Font Size:11/13 Text Width:125mm Depth:43 Lines Elsevier AMS Prelims-N52736 Job code: ASLA 17-2-2007 12:35p.m.