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The Journal of Immunology is published twice each month by The American Association of Immunologists, Inc., 1451 Rockville Pike, Suite 650, Rockville, MD 20852 All rights reserved. Print ISSN: 0022-1767 Online ISSN: 1550-6606. VOL. 189 | NO. 5 | September 1, 2012 | Pages 2067–2686

2067 IN THIS ISSUE

PILLARS OF IMMUNOLOGY 2069 Cytokine Mimicry with an Immunologic Reformation: The Discovery of a Decade Kenneth M. Murphy

2072 Pillars Article: Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI. Science. 1990. 248: 1230–1234

Kevin W. Moore, Paulo Vieira, David F. Fiorentino, Mary L. Trounstine, Tariq A. Khan, and Timothy R. Mosmann Downloaded from

CUTTING EDGE 2079 Cutting Edge: Suppression of GM-CSF Expression in Murine and Human T Cells by IL-27 Andrew Young, Eimear Linehan, Emily Hams, Aisling C. O’Hara Hall, Angela McClurg, James A. Johnston, Christopher A. Hunter, Padraic G. Fallon, and Denise C. Fitzgerald http://www.jimmunol.org/

2084 Cutting Edge: Influence of Tmevpg1, a Long Intergenic Noncoding RNA, on the Expression of Ifng by Th1 Cells Sarah P. Collier, Patrick L. Collins, Christopher L. Williams, Mark R. Boothby, and Thomas M. Aune

2089 Cutting Edge: IL-10–Mediated Tristetraprolin Induction Is Part of a Feedback Loop That Controls Macrophage STAT3 Activation and Cytokine Production Anthony Gaba, Sergei I. Grivennikov, Mahn Vu Do, Deborah J. Stumpo, Perry J. Blackshear, and Michael Karin by guest on September 23, 2021

2094 Cutting Edge: Lymphoid Tissue Inducer Cells Maintain Memory CD4 T Cells within Secondary Lymphoid Tissue David R. Withers, Fabrina M. Gaspal, Emma C. Mackley, Clare L. Marriott, Ewan A. Ross, Guillaume E. Desanti, Natalie A. Roberts, Andrea J. White, Adriana Flores-Langarica, Fiona M. McConnell, Graham Anderson, and Peter J. L. Lane

On the cover: A section of murine mesenteric lymph node stained for expression of RORg (green), IL-7Ra (yellow), and 2 CD3 (blue) counterstained with a nuclear dye (gray). Clusters of lymphoid tissue inducer cells (RORg+IL-7Ra+CD3 ) are found at the subcapsular sinus and interfollicular areas, sites of entry and recirculation for lymphocytes. Withers, D. R., F. M. Gaspal, E. C. Mackley, C. L. Marriott, E. A. Ross, G. E. Desanti, N. A. Roberts, A. J. White, A. Flores-Langarica, F. M. McConnell, G. Anderson, and P. J. L. Lane. 2012. Cutting Edge: Lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue. J. Immunol. 189: 2094–2098.

The Journal of Immunology (ISSN 0022-1767) is published twice each month by The American Association of Immunologists, Inc., 9650 Rockville Pike, Bethesda, MD 20814-3994, Phone: 301-634-7197, Fax: 301-634-7829. Subscription terms: New subscriptions and renewals begin January 1 and expire one year later (see http://www.jimmunol.org/subscriptions for prices and details). A special rate is available to members of The American Association of Immunologists, Inc. (see http://www.aai.org/ membership). The American Association of Immunologists, Inc., is not responsible for undeliverable issues. Replacement issues can be obtained, if available, at the regular price of single issues (see http://www.jimmunol.org/pdf/single_issue_purchase.pdf). Reprints of individual articles are available only from authors. Periodicals postage paid at Bethesda, MD 20814-3994, and at additional mailing offices. Country of origin U.S.A. Printed on acid-free recyclable paper. Postmaster: Send address changes 60 days in advance to The Journal of Immunology, Subscription Department, 9650 Rockville Pike, Bethesda, MD 20814-3994. Copyright Ó 2012 by The American Association of Immunologists, Inc. CELLULAR IMMUNOLOGY AND IMMUNE REGULATION 2099 NK Cells Regulate CD8+ T Cell Priming and Dendritic Cell Migration during Influenza A Infection by IFN-g and Perforin-Dependent Mechanisms Moyar Qing Ge, Adrian W. S. Ho, Yafang Tang, Kenneth H. S. Wong, Benson Y. L. Chua, Stephan Gasser, and David Michael Kemeny

2110 Immune Suppression and Resistance Mediated by Constitutive Activation of Wnt/b-Catenin Signaling in Human Melanoma Cells Tomonori Yaguchi, Yasufumi Goto, Kenji Kido, Hiroshi Mochimaru, Toshiharu Sakurai, Nobuo Tsukamoto, Chie Kudo-Saito, Tomonobu Fujita, Hidetoshi Sumimoto, and Yutaka Kawakami

2118 CD8+CD45RA+CCR7+FOXP3+ T Cells with Immunosuppressive Properties: A Novel Subset of Inducible Human Regulatory T Cells Masakatsu Suzuki, Ann L. Jagger, Christine Konya, Yasuhiro Shimojima, Sergey Pryshchep, Jo¨rgJ. Goronzy, and Cornelia M. Weyand

2131 A Genetically Encoded IL-1b Bioluminescence Resonance Energy Transfer Sensor To Monitor Inflammasome Activity Vincent Compan, Alberto Baroja-Mazo, Laricia Bragg, Alexei Verkhratsky, Julie Perroy, and Pablo Pelegrin Downloaded from

2138 The 3BP2 Adapter Protein Is Required for Chemoattractant-Mediated Neutrophil Activation Grace Chen, Ioannis Dimitriou, Laura Milne, Karl S. Lang, Philipp A. Lang, Noah Fine, Pamela S. Ohashi, Paul Kubes, and Robert Rottapel

2151 Inhibition of Mechanistic Target of Rapamycin Promotes Dendritic Cell Activation and Enhances http://www.jimmunol.org/ Therapeutic Autologous Vaccination in Mice Eyal Amiel, Bart Everts, Tori C. Freitas, Irah L. King, Jonathan D. Curtis, Erika L. Pearce, and Edward J. Pearce

2159 Cytokine Secretion by CD4+ T Cells at the Immunological Synapse Requires Cdc42-Dependent Local Actin Remodeling but Not Microtubule Organizing Center Polarity Karine Chemin, Armelle Bohineust, Stephanie Dogniaux, Marie Tourret, Sarah Guegan, Francesc Miro, and Claire Hivroz

2169 Decoding the Regulation of Mast Cell Exocytosis by Networks of Rab GTPases by guest on September 23, 2021 Nurit P. Azouz, Takahide Matsui, Mitsunori Fukuda, and Ronit Sagi-Eisenberg

2181 Impaired Humoral Immunity and Tolerance in K14-VEGFR-3-Ig Mice That Lack Dermal Lymphatic Drainage Susan N. Thomas, Joseph M. Rutkowski, Miriella Pasquier, Emma L. Kuan, Kari Alitalo, Gwendalyn J. Randolph, and Melody A. Swartz

2191 Neutrophil Expression of Fas Ligand and Perforin Directs Effector CD8 T Cell Infiltration into Antigen-Challenged Skin Danielle D. Kish, Anton V. Gorbachev, Neetha Parameswaran, Neetu Gupta, and Robert L. Fairchild

2203 The Protein Tyrosine Phosphatase SHP-1 Regulates Phagolysosome Biogenesis Carolina P. Gomez, Marina Tiemi Shio, Pascale Duplay, Martin Olivier, and Albert Descoteaux

2211 GB Virus C Envelope Protein E2 Inhibits TCR-Induced IL-2 Production and Alters IL-2–Signaling Pathways Nirjal Bhattarai, James H. McLinden, Jinhua Xiang, Thomas M. Kaufman, and Jack T. Stapleton

2217 Airway Epithelial Expression of TLR5 Is Downregulated in Healthy Smokers and Smokers with Chronic Obstructive Pulmonary Disease Rui Wang, Joumana Ahmed, Guoqing Wang, Ibrahim Hassan, Yael Strulovici-Barel, Jacqueline Salit, Jason G. Mezey, and Ronald G. Crystal

2226 Inhibition of CD73 Improves B Cell-Mediated Anti-Tumor Immunity in a Mouse Model of Melanoma Giovanni Forte, Rosalinda Sorrentino, Antonella Montinaro, Antonio Luciano, Ian M. Adcock, Piera Maiolino, Claudio Arra, Carla Cicala, Aldo Pinto, and Silvana Morello 2234 Resolution of Experimental Lung Injury by Monocyte-Derived Inducible Nitric Oxide Synthase Franco R. D’Alessio, Kenji Tsushima, Neil R. Aggarwal, Jason R. Mock, Yoshiki Eto, Brian T. Garibaldi, Daniel C. Files, Claudia R. Avalos, Jackie V. Rodriguez, Adam T. Waickman, Sekhar P. Reddy, David B. Pearse, Venkataramana K. Sidhaye, Paul M. Hassoun, Michael T. Crow, and Landon S. King

2246 Antibodies Generated against Conserved Antigens Expressed by Bacteria and Allergen-Bearing Fungi Suppress Airway Disease Nicholas W. Kin, Emily K. Stefanov, Brian L. P. Dizon, and John F. Kearney

2257 Rapid Differentiation of Monocytes into Type I IFN-Producing Myeloid Dendritic Cells as an Antiviral Strategy against Influenza Virus Infection Weiping Cao, Andrew K. Taylor, Renata E. Biber, William G. Davis, Jin Hyang Kim, Adrian J. Reber, Tatiana Chirkova, Juan A. De La Cruz, Aseem Pandey, Priya Ranjan, Jacqueline M. Katz, Shivaprakash Gangappa, and Suryaprakash Sambhara

2266 Nanotopography-Guided Migration of T Cells Keon Woo Kwon, Hyoungjun Park, Kwang Hoon Song, Jong-Cheol Choi, Hyungmin Ahn, Moon Jeong Park, Kahp-Yang Suh, and Junsang Doh Downloaded from 2274 Acquisition of MHC:Peptide Complexes by Dendritic Cells Contributes to the Generation of Antiviral CD8+ T Cell Immunity In Vivo Lesley A. Smyth, Catherine Hervouet, Thomas Hayday, Pablo D. Becker, Richard Ellis, Robert I. Lechler, Giovanna Lombardi, and Linda S. Klavinskis

2283 A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression http://www.jimmunol.org/ Claudia Volpi, Francesca Fallarino, Roberta Bianchi, Ciriana Orabona, Antonella De Luca, Carmine Vacca, Luigina Romani, Bruno Gran, Ursula Grohmann, Paolo Puccetti, and Maria L. Belladonna

2290 An NKp30-Based Chimeric Antigen Receptor Promotes T Cell Effector Functions and Antitumor Efficacy In Vivo Tong Zhang, Ming-Ru Wu, and Charles L. Sentman by guest on September 23, 2021 2300 Dynamics of the Splenic Innate-like CD19+CD45Rlo Cell Population from Adult Mice in Homeostatic and Activated Conditions Belen de Andres, Carmen Prado, Beatriz Palacios, Mario Al´ia, Sharmili Jagtap, Natalia Serrano, Isabel Cortegano, Miguel Angel R. Marcos, and Maria Luisa Gaspar

2309 A TCR Affinity Threshold Regulates Memory CD4 T Cell Differentiation following Vaccination Christina K. Baumgartner, Hideo Yagita, and Laurent P. Malherbe

2318 A c-Myc and Surface CD19 Signaling Amplification Loop Promotes B Cell Lymphoma Development and Progression in Mice Jonathan C. Poe, Veronique Minard-Colin, Evgueni I. Kountikov, Karen M. Haas, and Thomas F. Tedder

2326 Phospholipase Cg2 Plays a Role in TCR Signal Transduction and T Cell Selection Guoping Fu, Yuhong Chen, James Schuman, Demin Wang, and Renren Wen

2333 The Bone Marrow Functions as the Central Site of Proliferation for Long-Lived NK Cells Mary J. G. van Helden, Natascha de Graaf, Claire J. P. Boog, David J. Topham, Dietmar M. W. Zaiss, and Alice J. A. M. Sijts

2338 B7-DC-Ig Enhances Vaccine Effect by a Novel Mechanism Dependent on PD-1 Expression Level on T Cell Subsets Mikayel Mkrtichyan, Yana G. Najjar, Estella C. Raulfs, Linda Liu, Solomon Langerman, Geoffrey Guittard, Laurent Ozbun, and Samir N. Khleif

2348 Stability and Function of Secondary Th1 Memory Cells Are Dependent on the Nature of the Secondary Stimulus Chulwoo Kim, David C. Jay, and Matthew A. Williams MOLECULAR AND STRUCTURAL IMMUNOLOGY 2356 V(D)J Recombinase-Mediated TCR b Locus Gene Usage and Coding Joint Processing in Peripheral T Cells during Perinatal and Pediatric Development Janet M. Murray, Terri Messier, Jami Rivers, J. Patrick O’Neill, Vernon E. Walker, Pamela M. Vacek, and Barry A. Finette

2365 Identification of a Catalytic Exosite for Complement Component C4 on the Serine Protease Domain of C1s Renee C. Duncan, Frida Mohlin, Deni Taleski, Theresa H. Coetzer, James A. Huntington, Richard J. Payne, Anna M. Blom, Robert N. Pike, and Lakshmi C. Wijeyewickrema

2374 Activation-Induced Cytidine Deaminase-Initiated Off-Target DNA Breaks Are Detected and Resolved during S Phase Muneer G. Hasham, Kathy J. Snow, Nina M. Donghia, Jane A. Branca, Mark D. Lessard, Janet Stavnezer, Lindsay S. Shopland, and Kevin D. Mills

2383 A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing Irini Evnouchidou, James Birtley, Sergey Seregin, Athanasios Papakyriakou, Efthalia Zervoudi, Martina Samiotaki, George Panayotou, Petros Giastas, Olivia Petrakis, Dimitris Georgiadis, Andrea Amalfitano, Emmanuel Saridakis, Downloaded from Irene M. Mavridis, and Efstratios Stratikos

2393 ZBTB32 Is an Early Repressor of the CIITA and MHC Class II Gene Expression during B Cell Differentiation to Plasma Cells

Hye Suk Yoon, Christopher D. Scharer, Parimal Majumder, Carl W. Davis, Royce Butler, Wendy Zinzow-Kramer, http://www.jimmunol.org/ Ioanna Skountzou, Dimitrios G. Koutsonanos, Rafi Ahmed, and Jeremy M. Boss

IMMUNOGENETICS 2404 Recombinatorial Biases and Convergent Recombination Determine Interindividual TCRb Sharing in Murine Thymocytes Hanjie Li, Congting Ye, Guoli Ji, Xiaohui Wu, Zhe Xiang, Yuanyue Li, Yonghao Cao, Xiaolong Liu, Daniel C. Douek, David A. Price, and Jiahuai Han by guest on September 23, 2021 HOST DEFENSE 2414 Sialoadhesin Promotes Rapid Proinflammatory and Type I IFN Responses to a Sialylated Pathogen, Campylobacter jejuni Mariliis Klaas, Cornelia Oetke, Leanne E. Lewis, Lars P. Erwig, Astrid P. Heikema, Alistair Easton, Hugh J. Willison, and Paul R. Crocker

2423 Anti-Peptidoglycan Antibodies and Fcg Receptors Are the Key Mediators of Inflammation in Gram-Positive Sepsis Dawei Sun, Brent Raisley, Marybeth Langer, Janaki K. Iyer, Vidya Vedham, Jimmy L. Ballard, Judith A. James, Jordan Metcalf, and K. Mark Coggeshall

2432 CD8 T Cells Are Essential for Recovery from a Respiratory Vaccinia Virus Infection John Goulding, Rebecka Bogue, Vikas Tahiliani, Michael Croft, and Shahram Salek-Ardakani

2441 CD4+ T Cells Are Necessary and Sufficient To Confer Protection against Chlamydia trachomatis Infection in the Murine Upper Genital Tract David C. Gondek, Andrew J. Olive, Georg Stary, and Michael N. Starnbach

2450 Type I Alveolar Epithelial Cells Mount Innate Immune Responses during Pneumococcal Pneumonia Kazuko Yamamoto, Joseph D. Ferrari, Yuxia Cao, Maria I. Ramirez, Matthew R. Jones, Lee J. Quinton, and Joseph P. Mizgerd

2460 Olfactomedin 4 Inhibits Cathepsin C-Mediated Protease Activities, Thereby Modulating Neutrophil Killing of Staphylococcus aureus and Escherichia coli in Mice Wenli Liu, Ming Yan, Yueqin Liu, Kenneth R. McLeish, William G. Coleman, Jr., and Griffin P. Rodgers 2468 Integrin aXb2 Is a Leukocyte Receptor for Candida albicans and Is Essential for Protection against Fungal Infections Samir Jawhara, Elzbieta Pluskota, Dmitriy Verbovetskiy, Olena Skomorovska-Prokvolit, Edward F. Plow, and Dmitry A. Soloviev

2478 Human H-Ficolin Inhibits Replication of Seasonal and Pandemic Influenza A Viruses Anamika Verma, Mitchell White, Vinod Vathipadiekal, Shweta Tripathi, Julvet Mbianda, Micheal Ieong, Li Qi, Jeffery K. Taubenberger, Kazue Takahashi, Jens C. Jensenius, Steffen Thiel, and Kevan L. Hartshorn

2488 Endothelial Cells and Fibroblasts Amplify the Arthritogenic Type I IFN Response in Murine Lyme Disease and Are Major Sources of Chemokines in Borrelia burgdorferi-Infected Joint Tissue Robert B. Lochhead, F. Lynn Sonderegger, Ying Ma, James E. Brewster, Doug Cornwall, Heather Maylor-Hagen, Jennifer C. Miller, James F. Zachary, John H. Weis, and Janis J. Weis

2502 Differential Interaction of the Two Related Fungal Species Candida albicans and Candida dubliniensis with Human Neutrophils Eliska Svobodova, Peter Staib, Josephine Losse, Florian Hennicke, Dagmar Barz, and Mihaly Jozsi

2512 Heligmosomoides polygyrus bakeri Induces Tolerogenic Dendritic Cells that Block Colitis and Prevent

Antigen-Specific Gut T Cell Responses Downloaded from Arthur M. Blum, Long Hang, Tommy Setiawan, Joseph P. Urban, Jr., Korynn M. Stoyanoff, John Leung, and Joel V. Weinstock

2521 Negative Impact of IFN-g on Early Host Immune Responses to Retroviral Infection Amanda K. Duley, Mickael€ J.-Y. Ploquin, Urszula Eksmond, Christoph G. Ammann, Ronald J. Messer, Lara Myers, Kim J. Hasenkrug, and George Kassiotis http://www.jimmunol.org/

2530 CD4+ T Cell-Dependent IFN-g Production by CD8+ Effector T Cells in Mycobacterium tuberculosis Infection Tyler D. Bold and Joel D. Ernst

2537 Increased Susceptibility to Salmonella Infection in Signal Regulatory Protein a-Deficient Mice Lin-Xi Li, Shaikh M. Atif, Shirdi E. Schmiel, Seung-Joo Lee, and Stephen J. McSorley by guest on September 23, 2021 INFLAMMATION 2545 Chitin Elicits CCL2 from Airway Epithelial Cells and Induces CCR2-Dependent Innate Allergic Inflammation in the Lung Rene M. Roy, Marcel Wu¨thrich, and Bruce S. Klein

2553 Endothelial CD47 Promotes Vascular Endothelial-Cadherin Tyrosine Phosphorylation and Participates in T Cell Recruitment at Sites of Inflammation In Vivo Veronica Azcutia, Michael Stefanidakis, Naotake Tsuboi, Tanya Mayadas, Kevin J. Croce, Daiju Fukuda, Masanori Aikawa, Gail Newton, and Francis W. Luscinskas

2563 Prostaglandin E2 Induces Oncostatin M Expression in Human Chronic Wound Macrophages through Axl Receptor Tyrosine Kinase Pathway Kasturi Ganesh, Amitava Das, Ryan Dickerson, Savita Khanna, Narasimham L. Parinandi, Gayle M. Gordillo, Chandan K. Sen, and Sashwati Roy

2574 Proteinase 3, the Autoantigen in Granulomatosis with Polyangiitis, Associates with Calreticulin on Apoptotic Neutrophils, Impairs Macrophage Phagocytosis, and Promotes Inflammation Julie Gabillet, Arnaud Millet, Magali Pederzoli-Ribeil, Pascale Tacnet-Delorme, Loi¨c Guillevin, Luc Mouthon, Philippe Frachet, and Veronique Witko-Sarsat

2584 Dendritic Cell Sphingosine 1-Phosphate Receptor-3 Regulates Th1–Th2 Polarity in Kidney Ischemia–Reperfusion Injury Amandeep Bajwa, Liping Huang, Hong Ye, Krishna Dondeti, Steven Song, Diane L. Rosin, Kevin R. Lynch, Peter I. Lobo, Li Li, and Mark D. Okusa

2597 Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat Joan Claria, Jesmond Dalli, Stephanie Yacoubian, Fei Gao, and Charles N. Serhan 2606 The Role of Properdin in Zymosan- and Escherichia coli-Induced Complement Activation Morten Harboe, Peter Garred, Julie K. Lindstad, Anne Pharo, Fredrik Mu¨ller, Gregory L. Stahl, John D. Lambris, and Tom E. Mollnes

2614 Systemic Analysis of PPARg in Mouse Macrophage Populations Reveals Marked Diversity in Expression with Critical Roles in Resolution of Inflammation and Airway Immunity Emmanuel L. Gautier, Andrew Chow, Rainer Spanbroek, Genevieve Marcelin, Melanie Greter, Claudia Jakubzick, Milena Bogunovic, Marylene Leboeuf, Nico van Rooijen, Andreas J. Habenicht, Miriam Merad, and Gwendalyn J. Randolph

CLINICAL IMMUNOLOGY 2625 Glioma Big Potassium Channel Expression in Human Cancers and Possible T Cell Epitopes for Their Immunotherapy Lisheng Ge, Neil T. Hoa, Andrew N. Cornforth, Daniela A. Bota, Anthony Mai, Dong In Kim, Shiun-Kwei Chiou, Michelle J. Hickey, Carol A. Kruse, and Martin R. Jadus

2635 Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-b1 Signaling Chun Geun Lee, Erica L. Herzog, Farida Ahangari, Yang Zhou, Mridu Gulati, Chang-Min Lee, Xueyan Peng,

Carol Feghali-Bostwick, Sergio A. Jimenez, John Varga, and Jack A. Elias Downloaded from

2645 Noncovalent Assembly of Anti-Dendritic Cell Antibodies and Antigens for Evoking Immune Responses In Vitro and In Vivo Anne-Laure Flamar, Sandra Zurawski, Felix Scholz, Ingrid Gayet, Ling Ni, Xiao-Hua Li, Eynav Klechevsky, John Quinn, SangKon Oh, Daniel H. Kaplan, Jacques Banchereau, and Gerard Zurawski http://www.jimmunol.org/ 2656 Intratumoral hu14.18–IL-2 (IC) Induces Local and Systemic Antitumor Effects That Involve Both Activated T and NK Cells As Well As Enhanced IC Retention Richard K. Yang, Nicholas A. Kalogriopoulos, Alexander L. Rakhmilevich, Erik A. Ranheim, Songwon Seo, KyungMann Kim, Kory L. Alderson, Jacek Gan, Ralph A. Reisfeld, Stephen D. Gillies, Jacquelyn A. Hank, and Paul M. Sondel

2665 Functional Exhaustion of CD4+ T Lymphocytes during Primary Cytomegalovirus Infection

Pierre Antoine, Veronique Olislagers, Ariane Huygens, Sandra Lecomte, Corinne Liesnard, Catherine Donner, by guest on September 23, 2021 and Arnaud Marchant

2673 B Cell Memory to a Serogroup C Meningococcal Conjugate Vaccine in Childhood and Response to Booster: Little Association with Serum IgG Antibody Kirsten P. Perrett, Celina Jin, Elizabeth Clutterbuck, Tessa M. John, Amy P. Winter, Elizabeth Kibwana, Ly-Mee Yu, Nigel Curtis, and Andrew J. Pollard

CORRECTIONS 2682 Correction: Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals Sebastian Kreiter, Abderraouf Selmi, Mustafa Diken, Martin Sebastian, Phillip Osterloh, Hansjo¨rgSchild, Christoph Huber, € Ozlem Tu¨reci, and Ugur Sahin

2683 AUTHOR INDEX