7th Introductory Course
Microbiology and Immunology
January 21 – 25, 2013
Large Lecture Hall Institute of Plant Biology Zollikerstrasse 107 8008 Zurich
Monday 21st 09:00-09:15 Welcome: Hauke Hennecke
09:15-10:15 Students’ Session: T-Cells in Viral Infections & Allergies S01 – Vanessa Landtwing The Cross-Talk between Human Dendritic Cells and Natural Killer Cells S02 – Nicolas Baumann CD8 T cell immunity during murine cytomegalovirus (MCMV) infection S03 – Donald McHugh Epstein-Barr virus associated central nervous system lymphoma genesis after
selective loss of virus-specific T cell control S04 – Tess Brodie Characterization and reactivation of HIV latent reservoir Morning Break (10:15-10:30) 10:30-11:30 Students’ Session: Microbial Communities: Interaction & Cooperation S05 – Anne Leinweber Siderophore cooperation and the evolution of virulence S06 – Elena Butaite Siderophore cooperation in the environment S07 – Daniel Müller Metaproteomics of a synthetic phyllosphere community using SWATH-MS S08 – Martina Stöckli Microfluidic platforms for monitoring interaction between fungi & bacteria Lunch Break (11:30-13:00) 13:00-13:45 P01 – Silke Stertz (Intro: Renier Myburgh)
Host factors required for influenza A virus entry 13:45-14:30 P02 – Cornel Fraefel (Intro: Hulda Jonsdottir) Molecular Mechanisms of inter-action between HSV-1 and adeno-associated virus in co-infected cells Afternoon Break (14:30-15:00) 15:00-15:45 P03 – Mübeccel Akdis (Intro: Tess Brodie) Antigen specific T and B cell regulation 15:45-16:30 P04 – Salomé LeibundGut (Intro: Mareike Bindszus) Host defense against fungal infections 16:30-17:15 G01 – Eric Eichhorn, GIVAUDAN (Intro: Niels van der Velden) Enzymes at work: from basic research to applications in the pharmaceutical and flavours & fragrances industry
Tuesday 22nd
09:00-10:15 Students’ Session: Virulence Factors & Proteins in Pathogens S09 – Anne Buttgereit Identifying a microglia specific transcription factor S10 –Ismeta Curkic Bistable gene expression of the Salmonella Pathogenicity Island 1 (SPI-1) S11 –Franziska Schönherr Pathogen-derived factors controlling Candida albicans infections S12 –Giuseppina Fascellaro Adapting to stress – Investigating the dynamic of the mycobacterial pupylome S13 –Begonia Fudrini Characterization of protein accesory factors pafB and pafC Morning Break (10:15-10:30) 10:30-11:30 Students’ Session: Viral Diseases & Novel Diagnostics S14 –Hulda Jonsdottir Reverse genetic analysis of coronavirus-host interactions in primary human airway epithelium S15 –Eveline Kindler Impact of RNA modification on coronavirus-induced innate immune responses S16 –Ramon Marc Eichenberger Development of novel diagnostic tools for canine babesiosis S17 –Dagmara Lewandowska Metagenomic profiling of viral infections for improved virus diagnostic and infectious disease management in immune compromised patients. Lunch Break (11:30-13:00) 13:00-13:45 P05 – Rolf Kümmerli (Intro: Martina Stöckli) The evolution of cooperation in microbes 13:45-14:30 P06 – Hauke Hennecke (Intro:Kristina Poljak) Biogenesis of cytochrome oxidases in bacteria Afternoon Break (14:30-15:00) 15:00-15:45 P07 – Melanie Greter (Intro: Ana Chavez Steenbock) Cytokine control of the mononuclear phagocyte system 15:45-16:30 P08 – Riccardo Bernasconi (Intro: Kathrin Moor) Endoplasmic reticulum: the protein factory in eukaryotic cells Transfer to ETH-Zentrum 17:15-18:00 G02 – Shin Numao, NOVARTIS (Intro: Shuai Man), HG D 7.1 The science of high throughput screening: from academic to industrial science
Afterwards: MIM-Apéro, Dozentenfoyer (HG Floor J) until 22:00
Wednesday 23rd 09:00-10:15 Students’ Session: Interleukins in Infection & Inflammation S18 – Mareike Bindszus Role of IL-36 in Candida infection S19 – Ana Chavez Steenbock Role of IL-10 in a model of oral candidiasis S20 – Oliver Fabian Wirz Regulatory and effector function B cell subsets S21 – Simon Altmeier The role of IL-17 in the interaction of Candida albicans with the host epithelium S22 – Anna Müller Deciphering cytokine signaling in the gut mucosa Morning Break (10:15-10:30) 10:30-11:30 Students’ Session: Fighting HIV S23 – Kok Yik Lim Ex vivo and In vitro Investigation of HIV-1 Integration Sites S24 – Renier Myburgh Engineering an HIV resistant Immune System S25 – Emanuel Stiegeler Selection of DARPins able to block HIV entry S26 – Lucia Reh HIV transmission via free viruses and cell-to-cell transmission
Lunch Break (11:30-13:00) 13:00-13:45 P09 – Peter Kast (Intro: Raoul Rosenthal)
On Nature’s Playground: Enzymes Dissected by Directed Evolution 13:45-14:30 P10 – Markus Künzler (Intro: Katrin Zurfluh) Protein-mediated interactions of fungi with worms and bacteria Afternoon Break (14:30-15:00) 15:00-15:45 P11 – Annelies Zinkernagel (Intro: Nadja Leimer) Host Bacterial Interactions: How Gram positive bacteria circumvent host defenses 15:45-16:30 P12 – Roman Spörri (Intro: Vanessa Landtwing) Activation of antigen-presenting cells for immunity and tolerance
Thursday 24th
09:00-10:15 Students’ Session: Physiology: Novel Enzymes & Pathways S27 – Shuai Man
Glycosylation in bacteria and virus S28 – Elsy Ngwa Structure-function- characterisation of Saccharomyces cerevisiae STT3 S29 – Kristina Poljak Functional characterization of yeast OTase S30 – Raoul Rosenthal Challenging NADPH chemistry, the case of crotonyl-CoA carboxylase/reductase S31 – Lennart Schada von Borzyskowski Design and implementation of synthetic CO2-fixation pathways in
Methylobacterium extorquens Morning Break (10:15-10:30) 10:30-11:30 Student’s Session: Microbes & Food, Microbiota & Biofilms
S32 – Serranda Gashi Dysregulation of gut-associated immunity by food-borne nanoparticles (Acronym: Food N'Immunity) S33 – Deborah Patsch Microbiota-Derived Histamine - Relevance to Mucosal Immune Homeostasis S34 – Katrin Zurfluh Emergence of foodborne pathogens and commensal organisms expressing resistance to modern β-lactam and quinolone antibiotics Lunch Break (11:30-13:00) 13:15-14:00 P14 – Karin Metzner (Intro: Lucia Reh)
HIV-1 genomics: Diversity, evolution and small non-coding RNAs 14:00-14:45 P15 – Roberto Speck (Intro: Nicolas Baumann) HIV-infection: Is a cure feasible?
14:45-18:00 Foxtrail – An outdoor paper chase through Zurich (Starting Point: Main Station Zurich)
Afterwards: “One Beer” at the bQm (bQm Kultur Cafe & Bar Unter der Polyterrasse, Leonhardstr. 34, 8092 Zurich)
Friday 25th
09:00-10:15 Students’ Session: Immune System & Defense Mechanisms S35 – Caroline Lanz Characterzation of the antiviral activity of avian IFITM proteins against influenza viruses S36 – Kathrin Moor The ability of adaptive immunity to protect animals with bacterial killing deficiencies from Salmonella infection S37 – Niels van der Velden Toxicity-based identification of novel nematotoxic defense effector proteins from mushroom forming fungi S38 – Cédric Vogt Safe oral vaccine against Echinoccocus granulosis based on recombinant Bacillus subtilis S39 – Ana Raykova Humoral immune responses in humanized mice Morning Break (10:15-10:30)
10:30-11:30 Students’ Session: Pathogens & Diseases S40 – Sandra Wotzka Host responses driving maturation of the gut microbial ecosystem S41 – Nadja Leimer Consequences of Staphylococcus aureus - host cell interactions S42 – Katharina Palmer Search for candidate autoantigens & putative environmental triggers in Multiple Sclerosis S43 – Sandra Ivic HIV and gene engineering Lunch Break (11:30-13:00) 13:00-13:45 P13 – Martin Ackermann (Intro: Daniel Müller) On the biological relevance of bacterial individuality
13:45-14:00 Closing Remarks: Leo Eberl
List of Participants
NAME & INSTITUTION (ETH/Uni) E-MAIL – ADRESS
Altmeier Simon ETH [email protected] Bao Kai UZH [email protected] Baumann Nicolas ETH [email protected] Bindszus Mareike ETH [email protected] Brodie Tess UZH [email protected] Butaite Elena UZH [email protected] Buttgereit Anne ETH [email protected] Chavez Ana ETH [email protected] Steenbock Curkic Ismeta ETH [email protected] Ramon Eichenberger UZH [email protected] Marc Fascellaro Giuseppina UZH [email protected] Fudrini Begonia UZH [email protected] Gashi Serranda UZH [email protected] Ivic Sandra UZH [email protected] Jonsdottir Hulda ETH [email protected] Kindler Eveline ETH [email protected] Kok Yik Lim UZH [email protected] Landtwing Vanessa UZH [email protected] Lanz Caroline UZH [email protected] Leimer Nadja UZH [email protected] Leinweber Anne UZH [email protected] Lewandowska Dagmara UZH [email protected] Man Shuai ETH [email protected] McHugh Donal UZH [email protected] Moor Kathrin ETH [email protected] Müller Anna ETH [email protected] Müller Daniel ETH [email protected]
Myburgh Renier UZH [email protected] Ngwa Elsy ETH [email protected] Pallmer Katharina UZH [email protected] Patsch Deborah UZH [email protected] Poljak Kristina ETH [email protected] Raykova Ana UZH [email protected] Reh Lucia ETH [email protected] Rosenthal Raoul ETH [email protected] Schada von Lennart ETH [email protected] Borzyskowski Schönherr Franziska ETH [email protected] Stiegeler Emanuel ETH [email protected] Stöckli Martina ETH [email protected] van der Niels ETH [email protected] Velden Vogt Cédric UZH [email protected] Oliver Wirz UZH [email protected] Fabian Wotzka Sandra ETH [email protected] Zurfluh Katrin UZH [email protected]
Planning and Organization: Judith Zingg, MIM PhD Program Coordinator ETH Zurich, Institute of Microbiology, Wolfgang-Pauli-Strasse 10, HCI G 429 CH - 8093 Zurich, Switzerland, Phone: +41 44 632 04 06 [email protected]
Dr. Tobias J. Erb ETH Zurich, Institute of Microbiology, Wolfgang-Pauli-Strasse 10, HCI F 437 CH - 8093 Zurich, Switzerland, Phone: +41 44 632 36 54 [email protected]
Fabian Meister, Institute of Microbiology, Online Technical Support