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Electronic Supplementary Material (ESI) for Metallomics. This journal is © The Royal Society of Chemistry 2019

Consolidated list of up-regulated expressed at different Cr (VI) concentrations at time points

Cr (VI) 6 h 9 h 12 h 18 h 24 h 36 h concentration

1-(5-phosphoribosyl)- 23S rRNA (uracil-5-)- ComA2 family 2-isopropylmalate 50S ribosomal 5-amino-4-imidazole- 2-dehydropantoate 2- methyltransferase synthase protein L36 carboxylate reductase RumA carboxylase

ATP-dependent Clp 50S ribosomal NAD(P)H-dependent 2-isopropylmalate 50S ribosomal choline transporter ATP- protein L28 synthase protein L33 binding subunit ClpX CDP-glycerol-- poly(glycerophosphat dihydrofolate 50S ribosomal dihydrofolate 30S ribosomal DNA III e) reductase protein L33 reductase protein S14 subunit alpha glycerophosphotransf erase ATP-dependent Clp hypothetical protein hypothetical protein 30S ribosomal DNA polymerase III DNA polymerase III protease ATP- XA21_07930 BSF33_09680 protein S21 subunit gamma/tau subunit gamma/tau binding subunit ClpX Glutamyl 4-aminobutyrate--2- methionine--tRNA magnesium DNA-binding ATPase oxoglutarate transporter CorA response regulator precursor, serine transaminase proteinase SspA Ferredoxin- GntR family pathogenicity island DNA mismatch polysaccharide ATP-dependent dependent glutamate transcriptional protein repair protein MutS biosynthesis protein DNA RecG synthase regulator

100 mg L-1 CDP- recombination/mobili glycerol:glycerophos DNA polymerase III GNAT family N- dihydroxy-acid zation protein phate subunit alpha dehydratase () glycerophosphotransf erase D-ribose ABC Short-chain GNAT family N- A transporter - dehydrogenase/reduc glutamate synthase acetyltransferase (plasmid) binding protein tase SDR HAD family DNA polymerase X Siderophore hypothetical protein family biosynthesis protein alkyl hydroperoxide hypothetical protein, NAD synthetase GTP-binding protein reductase partial NAD-dependent methionine ABC succinate- HAD family amino acid ABC transporter substrate- semialdehyde hydrolase transporter permease binding protein dehydrogenase Short-chain Mercuric ion methionine--tRNA dehydrogenase/reduc beta-galactosidase reductase ligase tase SDR N-acetylmuramic Uncharacterised deoxyribose- pathogenicity island acid-6-phosphate protein phosphate aldolase protein etherase preprotein asparagine--tRNA NAD(P)H-dependent formyltetrahydrofolat subunit ligase oxidoreductase e deformylase YajC Short-chain class II fumarate sodium:proton dehydrogenase/reduc glutamate ligase hydratase antiporter tase SDR deoxyribose- sulfate VOC family protein lipase phosphate aldolase adenylyltransferase

100 mg L-1 acetyl-CoA dihydrofolate carboxylase magnesium transcriptional reductase carboxyltransferase transporter CorA regulator subunit alpha excinuclease ABC pathogenicity island universal stress racemase subunit B protein protein alkyl hydroperoxide phosphoglyceromuta glutamate ligase reductase se recombination/mobili alpha,alpha- hsp90-like protein zation protein phosphotrehalase (plasmid) hypothetical protein asparagine--tRNA sulfate AXY36_09940 ligase adenylyltransferase hypothetical protein, chorismate synthase valine--tRNA ligase partial damage-inducible protein CinA magnesium dihydroorotate transporter CorA dehydrogenase major facilitator elongation factor Ts superfamily protein glutamate synthase mercuric reductase subunit alpha methicillin resistance hsp90-like protein 100 mg L-1 protein methionine--tRNA hypothetical protein ligase A4A82_06020 hypothetical protein nitroreductase A4A82_09210 hypothetical protein oxidoreductase A4A82_13105 100 mg L-1

preprotein hypothetical protein translocase subunit AXY36_05920 YajC proline:sodium hypothetical protein symporter PutP AXY36_09360 succinate hypothetical protein dehydrogenase AXY36_09955 sulfate hypothetical protein adenylyltransferase BSF33_09455 tRNA uridine(34) 5- carboxymethylamino hypothetical protein methyl synthesis RES11_06070 MnmG urease subunit hypothetical protein gamma RES11_07055 hypothetical protein UF66_0386 hypothetical protein UF66_0831 hypothetical protein XA21_08735 hypothetical protein XA21_11195 hypothetical protein XA21_11670 lysyl-tRNA synthetase multidrug ABC transporter ATP- binding protein multidrug transporter 100 mg L-1

nicotinate phosphoribosyltransf erase nitronate monooxygenase phosphogluconate dehydrogenase (NADP(+)- dependent, decarboxylating) phosphoribosylamino imidazolesuccinocar boxamide synthase proline:sodium symporter PutP putative resolvase (plasmid) pyruvate decarboxylase RmuC recombination/mobili zation protein (plasmid) restriction endonuclease subunit M sodium-independent anion transporter sodium:proton antiporter 100 mg L-1

succinate- semialdehyde dehydrogenase (NADP(+)) sulfate adenylyltransferase tRNA (adenosine(37)- N6)- dimethylallyltransfer ase MiaA trehalose operon repressor 2,5-diketo-D- 1,4-dihydroxy-2- 1,4-dihydroxy-2- 3-oxoacyl-ACP 2-oxoglutarate 3-oxoacyl-ACP gluconic acid naphthoyl-CoA naphthoyl-CoA synthase dehydrogenase E1 synthase reductase synthase synthase 2,3- 23S rRNA bisphosphoglycerate- 23S rRNA methylase 30S ribosomal (adenine(2058)-N(6))-2-deoxyribose-5- 30S ribosomal independent (plasmid) protein S10 methyltransferase phosphate aldolase protein S10 phosphoglycerate Erm(B) mutase 2-oxoglutarate 23S rRNA (uracil-5-)- 2-isopropylmalate 50S ribosomal ferredoxin 30S ribosomal 3-hexulose-6- methyltransferase synthase protein L1 oxidoreductase protein S13 phosphate synthase RumA subunit alpha 30S ribosomal 50S ribosomal 30S ribosomal 3-hexulose-6- 30S ribosomal 30S ribosomal protein S20 protein L11 protein S15 phosphate synthase protein S16 protein S11 50S ribosomal 50S ribosomal 30S ribosomal 3-hydroxyacyl-CoA 30S ribosomal 30S ribosomal protein L32 protein L30 protein S16 dehydrogenase protein S18 protein S13

200 mg L-1 3-methyl-2- 50S ribosomal ABC transporter, 30S ribosomal oxobutanoate 30S ribosomal 30S ribosomal protein L36 ATP-binding protein protein S17 hydroxymethyltransf protein S19 protein S15 erase acetoin utilization ATP-dependent Zn 30S ribosomal 3-oxoacyl-ACP 30S ribosomal 30S ribosomal protein metallopeptidase protein S19 synthase protein S3 protein S16 antibiotic ABC 3-oxoacyl-[acyl- DNA gyrase subunit 30S ribosomal 30S ribosomal 30S ribosomal transporter ATP- carrier protein] A protein S20 protein S4 protein S20 binding protein reductase arginine--tRNA 30S ribosomal 30S ribosomal 30S ribosomal 30S ribosomal DNA helicase ligase protein S8 protein S1 protein S5 protein S3 DNA-directed RNA 50S ribosomal 30S ribosomal 30S ribosomal 30S ribosomal ATPase polymerase subunit protein L10 protein S10 protein S6 protein S4 beta' bifunctional N- acetylglucosamine-1- phosphate GTP-binding protein 50S ribosomal 30S ribosomal 30S ribosomal 30S ribosomal uridyltransferase/gluc TypA protein L23 protein S11 protein S7 protein S5 osamine-1-phosphate acetyltransferase Glutamyl chloramphenicol endopeptidase 50S ribosomal 30S ribosomal 30S ribosomal 30S ribosomal acetyltransferase precursor, serine protein L27 protein S13 protein S8 protein S7 proteinase SspA PTS system N- acetylglucosamine- 50S ribosomal 30S ribosomal 4-oxalocrotonate 30S ribosomal chorismate synthase specific IIBC protein L3 protein S15 tautomerase protein S8 component

200 mg L-1 5'(3')- deoxyribose- PolC-type DNA 50S ribosomal 30S ribosomal 30S ribosomal deoxyribonucleotidas phosphate aldolase polymerase III protein L30 protein S16 protein S9 e 50S ribosomal 30S ribosomal 50S ribosomal 50S ribosomal diacetyl reductase protein L31 protein S18 protein L1 protein L1 UDP-N- D-lactate acetylglucosamine 1- 50S ribosomal 30S ribosomal 50S ribosomal 50S ribosomal dehydrogenase carboxyvinyltransfer protein L33 protein S19 protein L10 protein L10 ase UDP-N- acetylmuramoylalany 8-amino-7- l-D-glutamyl-2, 6- 30S ribosomal 50S ribosomal 50S ribosomal DNA polymerase IV oxononanoate diaminopimelate--D- protein S2 protein L13 protein L13 synthase alanyl-D-alanine ligase aminoglycoside acetyltransferase and DNA polymerase X ATP synthase F0F1 30S ribosomal 50S ribosomal 50S ribosomal aminoglycoside family subunit delta protein S3 protein L14 protein L16 (plasmid) Ferredoxin- ATP-dependent Clp 30S ribosomal 50S ribosomal 50S ribosomal dependent glutamate arsenate reductase protease proteolytic protein S4 protein L17 protein L17 synthase subunit CDP-glycerol-- beta-ketoacyl-[acyl- poly(glycerophosphat glutamate synthase 30S ribosomal 50S ribosomal 50S ribosomal carrier-protein] e) subunit alpha protein S5 protein L18 protein L18 synthase II glycerophosphotransf erase glycerol phosphate 30S ribosomal 50S ribosomal 50S ribosomal lipoteichoic acid synthase large CTP synthetase protein S6 protein L21 protein L24 synthase subunit

200 mg L-1 GNAT family N- cation:proton D-alanine 30S ribosomal 50S ribosomal 50S ribosomal acetyltransferase antiporter aminotransferase protein S7 protein L22 protein L25 GntR family DNA-directed RNA division protein 30S ribosomal 50S ribosomal 50S ribosomal transcriptional polymerase subunit FtsW protein S8 protein L24 protein L27 regulator beta HAD family 30S ribosomal 50S ribosomal 50S ribosomal synthase NAD hydrolase protein S9 protein L25 protein L4 helicase- cytochrome aa3 Phosphate 4-oxalocrotonate 50S ribosomal 50S ribosomal AddAB subunit quinol oxidase acetyltransferase tautomerase protein L27 protein L5 AddB subunit II ferrichrome ABC 5'(3')- RNA-binding protein 50S ribosomal 50S ribosomal hypothetical protein transporter substrate- deoxyribonucleotidas S1 protein L29 protein L7/L12 binding protein e formate RecX family hypothetical protein 50S ribosomal 50S ribosomal ABC transporter dehydrogenase transcriptional A4A82_12595 protein L1 protein L3 ATP-binding protein accessory protein regulator fructose- hypothetical protein Translation 50S ribosomal 50S ribosomal ATP synthase F0F1 bisphosphate RES10_12085 elongation factor Ts protein L10 protein L31 subunit alpha aldolase UDP-N-acetyl-D- ATP-dependent Clp hypothetical protein glycerol-3-phosphate 50S ribosomal 50S ribosomal galactosamine protease proteolytic UF66_0386 dehydrogenase protein L13 protein L33 dehydrogenase subunit UDP-N- hypothetical protein glycine cleavage acetylglucosamine 1- 50S ribosomal 50S ribosomal ATP-dependent Zn UF66_0428 system protein H carboxyvinyltransfer protein L15 protein L4 metallopeptidase ase hypothetical protein Universal stress 50S ribosomal 50S ribosomal D-alanine glyoxalase UF66_1428 protein L17 protein L5 aminotransferase hypothetical protein hydroxymethylglutar 50S ribosomal 50S ribosomal DNA gyrase subunit aconitate hydratase UF66_2233 yl-CoA synthase protein L18 protein L6 A

200 mg L-1 8-amino-7- hypothetical protein hypothetical protein 50S ribosomal DNA polymerase X oxononanoate XA21_10855 (plasmid) protein L19 family synthase DNA ATP-dependent Clp hypothetical protein hypothetical protein 50S ribosomal starvation/stationary alanine racemase protease proteolytic XA21_11705 A4A82_06020 protein L21 phase protection subunit protein hypothetical protein hypothetical protein aldehyde 50S ribosomal ATP-dependent Zn DNA-binding protein XA22_02880 A4A82_10410 dehydrogenase protein L22 metallopeptidase CDP- glycerol:poly(glycero hypothetical protein hypothetical protein 50S ribosomal DNA-binding alpha/beta hydrolase phosphate) XA22_11305 A4A82_12170 protein L23 response regulator glycerophosphotransf erase DNA-directed RNA intracellular protease hypothetical protein 50S ribosomal aminoacyltransferase CTP synthetase polymerase subunit amidase AXY36_00580 protein L24 alpha MarR family bacillithiol DNA-directed RNA hypothetical protein 50S ribosomal Cell division protein transcriptional biosynthesis cysteine- polymerase subunit AXY36_07260 protein L29 FtsK regulator adding enzyme BshC beta bifunctional ornithine DNA-directed RNA hypothetical protein 50S ribosomal D-alanine monooxygenase acetyltransferase/N- polymerase subunit AXY36_09795 protein L3 aminotransferase acetylglutamate beta' synthase hypothetical protein catabolite control 50S ribosomal D-ribose transporter F0F1 ATP synthase multidrug transporter BSF33_00215 protein A protein L4 subunit RbsB subunit beta Nif3-like dinuclear hypothetical protein cell division protein 50S ribosomal FMN reductase metal center DNA helicase BSF33_10120 FtsZ protein L5 (NADPH) hexameric protein

200 mg L-1 non-canonical purine Fe-S cluster hypothetical protein cell division protein 50S ribosomal DNA NTP assembly protein BZ166_05325 GpsB protein L6 methyltransferase pyrophosphatase SufD inosine-5- peptide chain release dephospho-CoA 50S ribosomal DNA polymerase X monophosphate GTPase ObgE factor 2 kinase protein L7/L12 family dehydrogenase phosphopantothenoyl malate DNA-directed RNA LysR family dihydroxy-acid ABC transporter cysteine dehydrogenase polymerase subunit transcriptional dehydratase ATP-binding protein decarboxylase (acceptor) alpha regulator DNA-directed RNA ABC transporter, NAD(P)H-dependent phosphopentomutase methyltransferase enoyl-ACP reductase polymerase subunit ATP-binding protein oxidoreductase beta DNA-directed RNA pyruvate mobilization protein ATP synthase F0F1 NADH esterase polymerase subunit decarboxylase C (plasmid) subunit gamma dehydrogenase beta' recombination/mobili Domain of PTS glucose ATP-dependent zation protein octanoyltransferase ferritin uncharacterised transporter subunit DNA helicase (plasmid) function (DUF334) IIA CDP- restriction fructose- glycerol:poly(glycero Fe-S cluster peptidylprolyl Phosphate endonuclease subunit bisphosphate phosphate) assembly ATPase acetyltransferase S aldolase glycerophosphotransf SufC erase RNA-binding gamma- CtsR family Fe-S cluster RecX family proline transcriptional aminobutyrate transcriptional assembly protein transcriptional dehydrogenase accessory protein permease regulator SufB regulator Fe-S cluster pyridoxamine 5- glucosamine-6- D-alanine Serine protease assembly protein Serine protease phosphate oxidase phosphate isomerase aminotransferase SufD

200 mg L-1 Short-chain D-alanyl-lipoteichoic pyruvate glucose-6-phosphate GTP-binding protein Translation dehydrogenase/reduc acid biosynthesis decarboxylase isomerase TypA elongation factor Ts tase SDR protein DltD pyruvate dehydrogenase glutamine- UDP-N-acetyl-D- sucrose-6-phosphate DNA gyrase subunit Phosphate (acetyl-transferring) hydrolyzing GMP galactosamine hydrolase A acetyltransferase E1 component synthase dehydrogenase subunit alpha UDP-N- RecX family sulfate glutamyl-tRNA acetylglucosamine 1- DNA transcriptional adenylyltransferase amidotransferase carboxyvinyltransfer regulator ase UDP-N-acetyl-D- glutamyl-tRNA UDP-glucose 4- sulfite reductase recombinase A DNA-binding protein galactosamine reductase epimerase dehydrogenase UDP-N- recombination/mobili glutamyl-tRNA DNA-damage repair acetylglucosamine 1- tail protein zation protein synthetase protein carboxyvinyltransfer (plasmid) ase DNA-directed RNA restriction glycerol transporter polymerase subunit Urease beta subunit aconitate hydratase endonuclease dehydrogenase beta Fe-S cluster transporter associated ribulose-phosphate 3- glycerol-3-phosphate assembly ATPase adenylate kinase acyl carrier protein domain protein epimerase cytidylyltransferase SufC tRNA (adenosine(37)- hydroxymethylpyrimi N6)- short-chain GTP cyclohydrolase adenylosuccinate alkaline shock dine/phosphomethylp dimethylallyltransfer dehydrogenase FolE2 synthase protein 23 yrimidine kinase ase MiaA urease subunit short-chain fatty hypothetical protein GTPase ObgE aldo keto reductase aminoacyltransferase gamma acids transporter A4A82_03560

200 mg L-1 uroporphyrin-III stage V sporulation hypothetical protein aminoacyltransferase anti-anti-sigma factor methyltransferase protein G A4A82_06020 resolvase RecU succinyl-CoA:3- aspartyl/glutamyl- ketoacid-coenzyme hypothetical protein NADH tRNA aminopeptidase A subunit A4A82_08725 dehydrogenase amidotransferase B subunit A beta-ketoacyl-[acyl- hypothetical protein NADH-dependent transaldolase anti-anti-sigma factor carrier-protein] A4A82_09265 flavin oxidoreductase synthase II branched-chain alpha- hypothetical protein Na+/H+ antiporter anti-sigma B factor keto acid termination/antitermi A4A82_11275 subunit D RsbW dehydrogenase nation protein NusG subunit E2 PTS glucose transcriptional hypothetical protein aspartate alpha- cell division protein transporter subunit repressor CodY A4A82_12595 decarboxylase FtsZ IIA PTS mannnose hypothetical protein aspartate--tRNA cell division protein transketolase transporter subunit AXY36_01150 ligase GpsB IIA aspartyl/glutamyl- transposon DNA- hypothetical protein Putative cytosolic tRNA invertase AXY36_06780 protein amidotransferase subunit A triose-phosphate hypothetical protein RNA beta-ketoacyl-ACP cysteine synthase isomerase AXY36_09715 reductase

type I glyceraldehyde- hypothetical protein dihydrolipoyl 3-phosphate RepU (plasmid) BSF33_00215 dehydrogenase dehydrogenase

200 mg L-1 ureidoglycolate hypothetical protein Repressor CsoR of cell division protein dihydroxyacetone dehydrogenase BSF33_00755 the copZA operon FtsZ kinase subunit L hypothetical protein III virulence factor cysteine desulfurase elongation factor G BSF33_08575 family protein Rrf2 family hypothetical protein cysteine--tRNA transcriptional elongation factor P RES9_02285 ligase regulator hypothetical protein TIGR01440 family cytidine deaminase elongation factor Ts UF66_2233 protein Type I restriction- modification system, hypothetical protein dephospho-CoA DNA- elongation factor Tu XA21_07930 kinase methyltransferase subunit M UDP-N- hypothetical protein acetylglucosamine 1- elongation factor P enolase XA22_10040 carboxyvinyltransfer ase UDP-N- acetylmuramoylalany inosine-5- l-D-glutamyl-2, 6- monophosphate enoyl-ACP reductase enoyl-ACP reductase diaminopimelate--D- dehydrogenase alanyl-D-alanine ligase formate inositol UDP-glucose 4- excinuclease ABC dehydrogenase monophosphatase epimerase subunit A accessory protein iron ABC transporter UTP-glucose-1- fructose- fructose- substrate-binding phosphate bisphosphate bisphosphate protein uridylyltransferase aldolase aldolase

200 mg L-1 glucose-6-phosphate isoprenyl transferase Urease beta subunit general stress protein isomerase malate glutamine- [acyl-carrier-protein] glucose-6-phosphate dehydrogenase hydrolyzing GMP S-malonyltransferase isomerase (acceptor) synthase manganese ABC glutamine--fructose- acetyl-CoA glutamyl-tRNA transporter substrate- 6-phosphate acetyltransferase amidotransferase binding protein aminotransferase glyceraldehyde-3- metal-dependent phosphate glutamyl-tRNA acetyltransferase hydrolase dehydrogenase, amidotransferase partial molecular addiction module glycerol-3-phosphate glutamyl-tRNA GrpE antitoxin RelB dehydrogenase synthetase multidrug ABC glycerol-3-phosphate transporter ATP- adenylate kinase glyoxalase cytidylyltransferase binding protein heptaprenyl glycerol-3-phosphate nitrate reductase alanine--tRNA ligase pyrophosphate dehydrogenase synthase subunit A histidine--tRNA glycine C- peptidase aldo/keto reductase ligase acetyltransferase alkaline shock hydroxymethylglutar peptidase M23 glycine--tRNA ligase protein 23 yl-CoA synthase hydroxymethylpyrimi histidine ammonia- peptidase M24 aminopeptidase dine/phosphomethylp yrimidine kinase hypothetical protein phage protein anti-anti-sigma factor A4A82_03560

200 mg L-1 phosphoglucosamine anti-sigma B factor hypothetical protein hydroxymethylglutar 200 mg L-1 mutase RsbW A4A82_03720 yl-CoA synthase putative hydroxymethylpyrimi antitermination hypothetical protein transmembrane dine/phosphomethylp protein NusB A4A82_09265 protein yrimidine kinase arginine--tRNA hypothetical protein hypothetical protein putative transporter ligase A4A82_10890 A4A82_01085 pyridoxamine 5- aspartate alpha- hypothetical protein hypothetical protein phosphate oxidase decarboxylase AXY36_00580 A4A82_02240 aspartate--tRNA hypothetical protein hypothetical protein recombinase RecA ligase AXY36_01150 A4A82_03560 bifunctional 5,10- methylene- tetrahydrofolate hypothetical protein hypothetical protein recombinase RecB dehydrogenase/5,10- AXY36_02580 A4A82_04210 methylene- tetrahydrofolate cyclohydrolase branched-chain alpha- serine/threonine keto acid hypothetical protein hypothetical protein dehydrogenase AXY36_02715 A4A82_06020 subunit E2 short-chain capsule biosynthesis hypothetical protein hypothetical protein dehydrogenase protein CapA AXY36_05930 A4A82_07220 single-stranded DNA- cell division protein hypothetical protein hypothetical protein binding protein DivIVA AXY36_07260 A4A82_08725 stage V sporulation cell-cycle regulation hypothetical protein hypothetical protein protein HIT AXY36_09715 A4A82_09265 teichoic acid hypothetical protein hypothetical protein citrate synthase biosynthesis protein AXY36_09795 A4A82_11275 200 mg L-1

class I fructose- thiol reductase hypothetical protein hypothetical protein bisphosphate thioredoxin BSF33_00215 AXY36_01150 aldolase class II fumarate hypothetical protein hypothetical protein thioredoxin hydratase BSF33_00540 AXY36_06600 transcription hypothetical protein hypothetical protein termination/antitermi co-chaperone GroES BSF33_04620 BSF33_04470 nation protein NusG transcriptional hypothetical protein hypothetical protein cold-shock protein repressor CcpN BSF33_05765 BSF33_08575 transposon DNA- hypothetical protein hypothetical protein cysteine synthase invertase BSF33_13140 BSF33_11000 hypoxanthine cysteine--tRNA hypothetical protein trigger factor phosphoribosyltransf ligase RES9_02285 erase inosine-5- universal stress dihydrofolate hypothetical protein monophosphate protein reductase XA22_13145 dehydrogenase hypoxanthine dihydrolipoamide uridylate kinase phosphoribosyltransf lipase succinyltransferase erase imidazole glycerol malate:quinone virulence factor elongation factor G phosphate synthase oxidoreductase subunit HisH malonyl CoA-acyl lipid hydroperoxide elongation factor P carrier protein peroxidase transacylase manganese ABC elongation factor Tu transporter substrate- binding protein 200 mg L-1

fructose- metal-dependent molecular chaperone bisphosphate hydrolase DnaK aldolase multidrug ABC glucose-6-phosphate molecular chaperone transporter ATP- isomerase DnaK binding protein glycine C- ornithine--oxo-acid nucleoside- acetyltransferase transaminase diphosphate kinase glycine--tRNA ligase peptidase oligoribonuclease heptaprenyl pyrophosphate peptidase M28 peptidase synthase subunit A phosphogluconate dehydrogenase histidine--tRNA (NADP(+)- permease ligase dependent, decarboxylating) phosphoribosylformy histidinol-phosphate lglycinamidine peroxiredoxin aminotransferase synthase II phosphoenolpyruvate- hypothetical protein phosphotransacetylas protein A4A82_02240 e phosphotransferase putative N- hypothetical protein carbamoyl-beta- phosphoglycerate A4A82_04790 alanine kinase amidohydrolase phosphopantothenoyl hypothetical protein putative transporter cysteine A4A82_05255 decarboxylase 200 mg L-1

hypothetical protein pyruvate, phosphate phosphopyruvate A4A82_06335 dikinase hydratase putative hypothetical protein quinone phage/plasmid A4A82_07220 oxidoreductase primase reactive hypothetical protein intermediate/imine putative transporter A4A82_08725 deaminase hypothetical protein redox-regulated pyridoxamine 5- A4A82_08945 ATPase YchF phosphate oxidase hypothetical protein ribosomal protein pyruvate A4A82_09030 L7Ae decarboxylase pyruvate dehydrogenase hypothetical protein ribosome recycling (acetyl-transferring) A4A82_09265 factor E1 component subunit alpha hypothetical protein ribulose-phosphate 3- pyruvate kinase A4A82_10890 epimerase hypothetical protein scaffolding protein pyruvate oxidase AXY36_00580 hypothetical protein sodium-independent recombinase A AXY36_01585 anion transporter hypothetical protein stage V sporulation recombinase RecA AXY36_02415 protein G hypothetical protein thioredoxin-disulfide recombinase RecB AXY36_02580 reductase recombination/mobili hypothetical protein threonine synthase zation protein AXY36_06600 (plasmid) 200 mg L-1

hypothetical protein redox-regulated transaldolase AXY36_07245 ATPase YchF transcription hypothetical protein ribose-phosphate termination/antitermi AXY36_09935 pyrophosphokinase nation protein NusA hypothetical protein ribosome recycling transketolase BSF33_04620 factor hypothetical protein translation initiation serine/threonine BSF33_04630 factor IF-1 protein kinase hypothetical protein single-stranded DNA- transposase BSF33_05765 binding protein hypothetical protein sodium-independent trigger factor RES10_10450 anion transporter type I glyceraldehyde- succinate hypothetical protein 3-phosphate dehydrogenase RES11_04470 dehydrogenase flavoprotein subunit succinyl-CoA:3- hypothetical protein ketoacid-coenzyme uridylate kinase RES11_09065 A transferase subunit B teichoic acid hypothetical protein biosynthesis protein RES9_11625 F2 hypothetical protein thiol reductase UF66_0089 thioredoxin hypothetical protein transaldolase UF66_2291 hypothetical protein transcriptional XA21_08605 repressor CodY 200 mg L-1

hypothetical protein transketolase XA21_11860 hypothetical protein translation initiation XA22_07340 factor IF-1 inosine-5- transposon DNA- monophosphate invertase dehydrogenase lipase trigger factor lipid hydroperoxide triose-phosphate peroxidase isomerase malate type I glutamate-- dehydrogenase ammonia ligase (acceptor) malate:quinone universal stress oxidoreductase protein UspA manganese- uracil dependent inorganic phosphoribosyltransf pyrophosphatase erase mannitol-1- phosphate 5- dehydrogenase metal-dependent hydrolase methionine sulfoxide reductase molecular chaperone DnaK molecular chaperone GrpE molecular chaperone Hsp33 200 mg L-1

monooxygenase o-succinylbenzoate synthase ornithine--oxo-acid aminotransferase peptidase M28 permease phage tail protein phosphoenolpyruvate synthase regulatory protein phosphoglucosamine mutase phosphoglyceromuta se phosphotransacetylas e polysaccharide biosynthesis protein preprotein translocase subunit YajC primosomal protein N' putative DNA- binding protein, YbaB family putative phage/plasmid primase 200 mg L-1

pyridoxamine 5- phosphate oxidase quinone oxidoreductase ribonuclease R ribonucleotide- diphosphate reductase subunit beta ribosomal RNA small subunit methyltransferase H ribosomal protein L7Ae ribosome biogenesis GTPase Der ribosome biogenesis GTPase YqeH ribosome recycling factor ribulose-phosphate 3- epimerase serine hydroxymethyltransf erase sigma-54 modulation protein signal recognition particle stage V sporulation protein G 200 mg L-1

succinate--CoA ligase subunit beta sufurtransferase FdhD sulfite reductase subunit beta superoxide dismutase tRNA uridine(34) 5- carboxymethylamino methyl synthesis enzyme MnmG thioredoxin thymidylate synthase transaldolase transcriptional repressor CodY transketolase translation initiation factor IF-1 translation initiation factor IF-2 translation initiation factor IF-3 transposon DNA- invertase trigger factor two-component response regulator, LytR 200 mg L-1

type I glutamate-- ammonia ligase type I glyceraldehyde- 3-phosphate dehydrogenase universal stress protein UspA uracil phosphoribosyltransf erase urease subunit alpha uridylate kinase valine--tRNA ligase 2-oxoglutarate 1,4-dihydroxy-2- 2-dehydro-3- ferredoxin histidine ammonia- 3-ketoacyl-CoA GTP naphthoyl-CoA deoxyphosphoglucon oxidoreductase lyase pyrophosphokinase synthase ate aldolase subunit alpha 2,3- bisphosphoglycerate- hypothetical protein independent CTP synthetase CoA-transferase alpha/beta hydrolase DNA primase A4A82_08960 phosphoglycerate mutase bifunctional ornithine Rrf2 family 2,4-dienoyl-CoA hypothetical protein alpha/beta hydrolase DNA repair protein acetyltransferase/N- transcriptional reductase AXY36_09720 acetylglutamate regulator synthase 2-deoxyribose-5- dephospho-CoA F0F1 ATP synthase hypothetical protein cobalt ABC ribonuclease HII phosphate aldolase kinase subunit C XA21_11670 transporter ATPase 2-oxoglutarate metal-dependent ring-cleaving FAD-dependent lipoate-protein ligase parM protein dehydrogenase E1 hydrolase dioxygenase oxidoreductase A

300 mg L-1 2-oxoglutarate Fis family putative ferredoxin sodium:proton peptidase transcriptional transcriptional oxidoreductase antiporter regulator regulator (plasmid) subunit alpha 23S rRNA (uracil-5-)- spermidine/putrescin GTP-binding protein methyltransferase recombinase RecB sulfate permease e ABC transporter TypA RumA permease succinyl-CoA:3- 3-hexulose-6- Homoserine ketoacid-coenzyme scaffolding protein phosphate synthase dehydrogenase A transferase subunit B 3-methyl-2- oxobutanoate tRNA L-lactate sulfate permease hydroxymethyltransf methyltransferase dehydrogenase erase L-serine dehydratase, 3-oxoacyl-[acyl- iron-- carrier protein] dependent subunit reductase alpha 30S ribosomal Major myo-inositol protein S1 transporter IolT 30S ribosomal MobA/MobL family protein S11 protein PTS beta-glucoside 30S ribosomal transporter subunit protein S15 IIBC 30S ribosomal RNA helicase protein S19 30S ribosomal RND transporter protein S2

300 mg L-1 30S ribosomal acyl-CoA protein S3 dehydrogenase aldehyde 30S ribosomal dehydrogenase protein S5 family protein bifunctional 30S ribosomal riboflavin protein S6 kinase/FMN adenylyltransferase 30S ribosomal damage-inducible protein S7 protein DinB 5'(3')- formate deoxyribonucleotidas dehydrogenase e 50S ribosomal glutamate synthase protein L1 50S ribosomal glycerophosphodieste protein L10 r phosphodiesterase heme ABC 50S ribosomal transporter ATP- protein L14 binding protein 50S ribosomal hypothetical protein protein L15 (plasmid) 50S ribosomal hypothetical protein protein L19 BSF33_09115 50S ribosomal hypothetical protein protein L22 RES9_02800 50S ribosomal hypothetical protein protein L24 XA22_13430

300 mg L-1 50S ribosomal lactonase protein L25 nitric oxide reductase 50S ribosomal activation protein protein L29 NorQ 50S ribosomal peptidase M24 protein L30 50S ribosomal peptide chain release protein L6 factor 3 50S ribosomal phenylalanine--tRNA protein L7/L12 ligase subunit beta

6-phosphogluconate phosphoenolpyruvate dehydrogenase carboxykinase [ATP] 8-amino-7- phosphoglycerate oxononanoate dehydrogenase synthase ABC transporter phosphopyruvate (plasmid) hydratase ABC transporter serine protease SplE ATP-binding protein ATP synthase F0F1 site-specific subunit B ATP synthase F0F1 sporulation regulator subunit alpha WhiA teichoic acid ATP synthase F0F1 biosynthesis protein subunit delta B

300 mg L-1 ATP-dependent Clp -phosphate protease proteolytic pyrophosphorylase subunit ATP-dependent tranposase B DNA helicase transcription ATP-dependent Zn termination factor metallopeptidase Rho ArsR family type I methionyl transcriptional aminopeptidase regulator CDP-glycerol-- poly(glycerophosphat e) glycerophosphotransf erase CDP- glycerol:poly(glycero phosphate) glycerophosphotransf erase CoA-transferase D-alanine aminotransferase D-alanine--D-alanine ligase DNA gyrase subunit A DNA helicase DNA polymerase III subunit beta

300 mg L-1 DNA-binding protein DNA-directed RNA polymerase subunit beta F0F1 ATP synthase subunit beta F0F1 ATP synthase subunit epsilon FAD-dependent oxidoreductase Fe-S cluster assembly protein SufB Fis family transcriptional regulator GTP cyclohydrolase FolE2 GTP-binding protein TypA GTPase ObgE IMP dehydrogenase L-proline 3- hydroxylase Mobile element protein Molybdenum biosynthesis protein A

300 mg L-1 NAD-dependent dehydratase NADH dehydrogenase NADP-dependent oxidoreductase NIF3 protein Oligoendopeptidase F Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA PTS glucose transporter subunit IIA PTS mannnose transporter subunit IIA PadR family transcriptional regulator Phage lysin, N- acetylmuramoyl-L- alanine amidase Phosphate acetyltransferase Replication- associated protein

300 mg L-1 ThiJ/PfpI family protein Translation elongation factor Ts UDP-N-acetyl-D- galactosamine dehydrogenase UDP-N- acetylmuramate-- alanine ligase UDP-N- acetylmuramoylalany l-D-glutamyl-2, 6- diaminopimelate--D- alanyl-D-alanine ligase UDP-glucose 4- epimerase Uncharacterised protein Urease beta subunit YigZ family protein [acyl-carrier-protein] S-malonyltransferase acetate kinase acetyl-CoA carboxylase biotin carboxylase subunit aconitate hydratase acyl carrier protein

300 mg L-1 acyl-CoA dehydrogenase adenylate kinase adenylosuccinate synthase alanine dehydrogenase alanine--tRNA ligase dehydrogenase aldehyde dehydrogenase aldo/keto reductase alkaline shock protein 23 aminopeptidase anthranilate synthase component I anti-anti-sigma factor arginine repressor arsenate reductase aspartate alpha- decarboxylase aspartyl/glutamyl- tRNA amidotransferase subunit A beta-ketoacyl-ACP reductase

300 mg L-1 beta-ketoacyl-[acyl- carrier-protein] synthase II branched-chain alpha- keto acid dehydrogenase E1 branched-chain alpha- keto acid dehydrogenase subunit E2 cadmium resistance protein cell division protein DivIVA cell division protein FtsA cell division protein FtsZ cell division protein GpsB chorismate mutase citrate synthase cysteine desulfurase cysteine synthase cysteine--tRNA ligase cytochrome aa3 quinol oxidase subunit II dehydrogenase

300 mg L-1 dephospho-CoA kinase diaminopimelate decarboxylase dihydrolipoamide succinyltransferase dihydrolipoyl dehydrogenase dihydroxy-acid dehydratase dihydroxyacetone 300 mg L-1 kinase subunit L elongation factor G elongation factor P elongation factor Tu endopeptidase Clp ATP-binding subunit C enolase enoyl-ACP reductase excinuclease ABC subunit A excinuclease ABC subunit B exported protein ferrichrome ABC transporter substrate- binding protein ferritin 300 mg L-1

formate-- tetrahydrofolate ligase fructose- bisphosphate aldolase general stress protein

glucosamine-6- phosphate isomerase

glucose-6-phosphate isomerase glutamate dehydrogenase glutamate synthase glutamate-1- semialdehyde aminotransferase glutamine--fructose- 6-phosphate aminotransferase glutamine- hydrolyzing GMP synthase glycerol-3-phosphate cytidylyltransferase glycine C- acetyltransferase 300 mg L-1

glycine cleavage system protein T glycine dehydrogenase glycine dehydrogenase subunit 2 glycine--tRNA ligase

glycine/betaine ABC transporter permease

heme-binding protein hsp90-like protein hydroxymethylglutar yl-CoA synthase hydroxymethylpyrimi dine/phosphomethylp yrimidine kinase hypothetical protein A4A82_02240 hypothetical protein A4A82_03560 hypothetical protein A4A82_03720 hypothetical protein A4A82_03930 hypothetical protein A4A82_06020 300 mg L-1

hypothetical protein A4A82_07220 hypothetical protein A4A82_08945 hypothetical protein A4A82_09030 hypothetical protein A4A82_12170 hypothetical protein A4A82_12600 hypothetical protein AXY36_02415 hypothetical protein AXY36_02580 hypothetical protein AXY36_03305 hypothetical protein AXY36_06600 hypothetical protein AXY36_06780 hypothetical protein BSF33_00215 hypothetical protein BSF33_00755 hypothetical protein BSF33_04620 hypothetical protein BSF33_05765 hypothetical protein BSF33_08575 300 mg L-1

hypothetical protein BSF33_12980 hypothetical protein BZ166_05325 hypothetical protein RES10_10450 hypothetical protein RES10_11420 hypothetical protein RES11_04470 hypothetical protein RES11_09065 hypothetical protein RES9_02285 hypothetical protein RES9_11625 hypothetical protein UF66_1532 hypothetical protein UF66_2021 hypothetical protein XA21_11805 hypothetical protein XA21_11860 hypothetical protein XA21_13400 hypothetical protein XA22_10040 hypoxanthine phosphoribosyltransf erase 300 mg L-1

iron ABC transporter substrate-binding protein isoleucine--tRNA ligase isoleucyl-tRNA synthetase, partial lactate dehydrogenase late competence protein ComEC leucyl aminopeptidase lipid hydroperoxide peroxidase lipoate--protein ligase long-chain fatty acid-- CoA ligase malate dehydrogenase malate:quinone oxidoreductase manganese ABC transporter substrate- binding protein mannitol-1- phosphate 5- dehydrogenase metal-dependent hydrolase 300 mg L-1

methionine ABC transporter substrate- binding protein methionine sulfoxide reductase molecular chaperone DnaK molecular chaperone Hsp33 nitronate monooxygenase nuclease SbcCD subunit C nucleoside- diphosphate kinase oligoribonuclease oxidoreductase peptidase peptidase M28 phosphoenolpyruvate carboxykinase phosphoenolpyruvate synthase regulatory protein phosphoglyceromuta se phosphonate ABC transporter ATP- binding protein 300 mg L-1

polynucleotide preprotein translocase subunit SecA protein rlx pseudouridine synthase putative DNA- binding protein, YbaB family putative alpha- acetolactate decarboxylase putative phage/plasmid primase pyrimidine- nucleoside phosphorylase pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha pyruvate oxidase pyruvate, phosphate dikinase recombinase A recombinase RecB recombinase XerD 300 mg L-1

ribonuclease J ribose-phosphate pyrophosphokinase ribosomal protein L7Ae ribosome biogenesis GTPase Der ribosome recycling factor ribulose-phosphate 3- epimerase scaffolding protein serine hydroxymethyltransf erase short-chain dehydrogenase sigma-54 modulation protein signal recognition particle succinate dehydrogenase flavoprotein subunit succinate--CoA ligase subunit alpha succinate--CoA ligase subunit beta superoxide dismutase 300 mg L-1

teichoic acid biosynthesis protein thiol reductase thioredoxin thioredoxin thioredoxin-disulfide reductase thymidine phosphorylase thymidylate kinase transcription elongation factor GreA transcriptional repressor CodY transketolase translation initiation factor IF-2 translation initiation factor IF-3 transposase trigger factor two-component response regulator, LytR type I glutamate-- ammonia ligase type I methionyl aminopeptidase universal stress protein UspA 300 mg L-1

uracil phosphoribosyltransf erase uridylate kinase uroporphyrinogen decarboxylase virulence factor 50S ribosomal gamma- 50S ribosomal 30S ribosomal 50S ribosomal 30S ribosomal protein L28 aminobutyrate protein L32 protein S17 protein L11 protein S17 DNA polymerase III DNA polymerase III 50S ribosomal 50S ribosomal 30S ribosomal subunit alpha subunit gamma/tau protein L11 protein L23 protein S19 beta-ketoacyl-[acyl- alkyl hydroperoxide hypothetical protein 50S ribosomal 50S ribosomal 30S ribosomal carrier-protein] reductase BSF33_00540 protein L14 protein L30 protein S2 synthase II class I fructose- phosphotransacetylas 50S ribosomal 6-phosphogluconate 50S ribosomal esterase bisphosphate e protein L30 dehydrogenase protein L11 aldolase Glutamyl multidrug ABC formate 6-phosphogluconate endopeptidase 50S ribosomal transporter ATP- dehydrogenase dehydrogenase precursor, serine protein L14 binding protein accessory protein proteinase SspA ABC transporter NAD(P)-dependent 50S ribosomal nitroreductase (plasmid) oxidoreductase protein L15 ATP-dependent Clp beta-ketoacyl-[acyl- 50S ribosomal peptidase M23 protease ATP- carrier-protein] protein L23 binding subunit ClpX synthase II

100 + 200 mg L-1 phosphogluconate dehydrogenase ATP-dependent Clp 50S ribosomal (NADP(+)- protease proteolytic glucokinase protein L3 dependent, subunit decarboxylating) sufurtransferase DNA 50S ribosomal hsp90-like protein FdhD methyltransferase protein L30 DNA-directed RNA multidrug ABC 50S ribosomal polymerase subunit transporter ATP- protein L6 alpha binding protein Ferredoxin- phosphoglucosamine 6-phosphogluconate 100 + 200 mg dependent glutamate mutase dehydrogenase L-1 synthase Glutamyl ATP-dependent Clp endopeptidase polysaccharide protease ATP- precursor, serine biosynthesis protein binding subunit ClpX proteinase SspA pyridoxamine 5- deoxyribose- N-acetyltransferase phosphate oxidase phosphate aldolase NAD(P)-dependent hypothetical protein recombinase RecA oxidoreductase RES9_02285 transcription cell division protein lipid hydroperoxide elongation factor FtsA peroxidase GreA malate deoxyribose- dehydrogenase phosphate aldolase (acceptor) phosphoglucosamine glucokinase mutase hypothetical protein prephenate A4A82_12595 dehydrogenase 100 + 200 mg L-1

type I glyceraldehyde- hypothetical protein 3-phosphate AXY36_08620 dehydrogenase methionine--tRNA ligase putative transporter teichoic acid biosynthesis protein transcription elongation factor GreA urease subunit gamma 1-pyrroline-5- 1,4-dihydroxy-2- 1,4-dihydroxy-2- 30S ribosomal 30S ribosomal carboxylate naphthoyl-CoA DNA primase naphthoyl-CoA protein S20 protein S6 dehydrogenase synthase synthase 5'- 5'(3')- methylthioadenosine/ 2-oxoisovalerate hypothetical protein 50S ribosomal deoxyribonucleotidas acyl carrier protein S- dehydrogenase RES9_02800 protein L25 e adenosylhomocystein e nucleosidase 3-hydroxyacyl-CoA Oligoendopeptidase translation initiation hypothetical protein 50S ribosomal acetate--CoA ligase dehydrogenase F factor IF-1 A4A82_08725 protein L21 30S ribosomal 50S ribosomal acetate kinase acyl carrier protein protein S10 protein L29 30S ribosomal aldehyde adenylosuccinate 50S ribosomal protein S16 dehydrogenase synthase protein L31 30S ribosomal aldehyde 50S ribosomal aminoacyltransferase protein S17 dehydrogenase protein L36

200 + 300 mg L-1 30S ribosomal aminopeptidase arsenate reductase cold-shock protein protein S18 30S ribosomal aspartate enoyl-ACP reductase superoxide dismutase protein S9 aminotransferase 4,4'- ATP-dependent Clp glucose-6-phosphate diaponeurosporenoat protease ATP- isomerase e glycosyltransferase binding subunit ClpC 50S ribosomal D-alanine--D-alanine protein L18 ligase 50S ribosomal hypothetical protein dihydroxy-acid protein L21 AXY36_04620 dehydratase multidrug ABC 50S ribosomal transporter ATP- DNA helicase protein L33 binding protein DNA 50S ribosomal starvation/stationary oligoribonuclease protein L4 phase protection protein phosphoenolpyruvate- DNA-directed RNA ATP synthase F0F1 protein polymerase subunit subunit gamma phosphotransferase beta' ATP-dependent Clp preprotein excinuclease ABC protease ATP- translocase subunit subunit A binding subunit ClpX SecA DNA putative ferrichrome ABC starvation/stationary phage/plasmid transporter substrate- phase protection primase binding protein protein

200 + 300 mg L-1 DNA-directed RNA Fe-S cluster polymerase subunit pyruvate oxidase assembly protein beta' SufB Glutamyl endopeptidase glutamate precursor, serine dehydrogenase proteinase SspA Lanthionine glutamine biosynthesis protein amidotransferase LanL glutamine--fructose- Major myo-inositol 6-phosphate transporter IolT aminotransferase UDP-N- glutamine- acetylglucosamine 1- hydrolyzing GMP carboxyvinyltransfer synthase ase glutaryl-CoA acetate--CoA ligase dehydrogenase acetyl-CoA glycerol-3-phosphate acetyltransferase cytidylyltransferase alanine racemase glyoxalase aminoacyltransferase GTPase Era hypothetical protein autolysin A4A82_03560 hypothetical protein beta-galactosidase AXY36_04520

200 + 300 mg L-1 bifunctional 5,10- methylene- 200 + 300 mg tetrahydrofolate L-1 hypothetical protein dehydrogenase/5,10- BSF33_12980 methylene- tetrahydrofolate cyclohydrolase catabolite control intracellular protease protein A amidase iron citrate ABC catalase transporter substrate- binding protein class I fructose- isoleucine--tRNA bisphosphate ligase aldolase class II fumarate long-chain fatty acid-- hydratase CoA ligase NAD-dependent glucokinase dehydratase glutamyl-tRNA NIF3 protein synthetase glutaryl-CoA peptidase dehydrogenase prolyl-tRNA glycerol kinase synthetase glycerol-3-phosphate protein rlx dehydrogenase glyoxalase pyruvate oxidase hydroxyacid recombinase RecA dehydrogenase 200 + 300 mg L-1

hypothetical protein recombinase XerD AXY36_00580 hypothetical protein RLX protein AXY36_07855 hypothetical protein scaffolding protein BSF33_00540 hypothetical protein short-chain BSF33_09115 dehydrogenase isocitrate thiol reductase dehydrogenase thioredoxin magnesium thioredoxin-disulfide transporter CorA reductase malate transcription dehydrogenase termination/antitermi (acceptor) nation protein NusG UDP-N- ornithine--oxo-acid acetylmuramate-- aminotransferase alanine ligase phosphoenolpyruvate- Uncharacterised protein protein phosphotransferase undecaprenyldiphosp ho- phosphotransacetylas muramoylpentapepti e de beta-N- acetylglucosaminyltr ansferase preprotein translocase subunit virulence factor YajC 200 + 300 mg L-1

pyridoxamine 5- phosphate oxidase pyruvate kinase single-stranded DNA- binding protein stage V sporulation protein G transaldolase transcriptional regulator triose-phosphate isomerase type I glyceraldehyde- 3-phosphate dehydrogenase urease subunit alpha 3-hydroxy-3- alkyl hydroperoxide methylglutaryl-CoA elongation factor Ts reductase reductase phosphopyruvate epimerase hydratase esterase 100 + 300 mg glycosyl transferase L-1 family 2 octanoyltransferase polyribonucleotide nucleotidyltransferas e 100 + 300 mg L-1

succinate dehydrogenase 30S ribosomal 6-phosphogluconate 50S ribosomal 30S ribosomal octanoyltransferase protein S13 dehydrogenase elongation factor Ts protein L33 protein S10 NAD(P)-dependent prephenate 50S ribosomal alpha/beta hydrolase elongation factor Ts autolysin oxidoreductase dehydrogenase protein L22 asparagine--tRNA cell division protein NAD(P)-dependent hypothetical protein ligase octanoyltransferase GpsB oxidoreductase DNA hypothetical protein phosphopyruvate enoyl-ACP reductase octanoyltransferase methyltransferase RES9_02285 hydratase DNA-directed RNA NAD(P)-dependent hypothetical protein polysaccharide polymerase subunit prephenate oxidoreductase A4A82_03720 biosynthesis protein alpha dehydrogenase hypothetical protein lysine--tRNA ligase peptidase M23 FdhD AXY36_01150 100 + 200 + phosphogluconate 300 mg L-1 manganese- dehydrogenase hypothetical protein dependent inorganic (NADP(+)- RES9_02285 pyrophosphatase dependent, decarboxylating) NAD(P)-dependent prephenate prephenate oxidoreductase dehydrogenase dehydrogenase octanoyltransferase recombinase RecA sulfurtransferase phosphoglucosamine mutase prephenate dehydrogenase recombinase RecA universal stress protein