AIPET Syllabus for Periodontology – Paper – II
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Journal of Dental Research
Journal of Dental Research http://jdr.sagepub.com/ Cell Differentiation and Matrix Organization in Engineered Teeth A. Nait Lechguer, M.L. Couble, N. Labert, S. Kuchler-Bopp, L. Keller, H. Magloire, F. Bleicher and H. Lesot J DENT RES 2011 90: 583 originally published online 4 February 2011 DOI: 10.1177/0022034510391796 The online version of this article can be found at: http://jdr.sagepub.com/content/90/5/583 Published by: http://www.sagepublications.com On behalf of: International and American Associations for Dental Research Additional services and information for Journal of Dental Research can be found at: Email Alerts: http://jdr.sagepub.com/cgi/alerts Subscriptions: http://jdr.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav >> Version of Record - Apr 13, 2011 OnlineFirst Version of Record - Feb 4, 2011 What is This? Downloaded from jdr.sagepub.com at Service Commun de la Documentation Université de Strasbourg on September 6, 2013 For personal use only. No other uses without permission. © 2011 International & American Associations for Dental Research RESEARCH REPORTS Biomaterials & Bioengineering A. Nait Lechguer1,2, M.L. Couble3,4, N. Labert3,4, S. Kuchler-Bopp1,2, Cell Differentiation and L. Keller1,2, H. Magloire3,4, F. Bleicher3,4, Matrix Organization in and H. Lesot1,2* Engineered Teeth 1INSERM UMR 977, Faculté de Médecine, 11, rue Humann, F-67085 Strasbourg, France; 2Dental School, University of Strasbourg, Strasbourg, France; 3Université de Lyon, Faculté d’Odontologie, Rue Guillaume Paradin, F-69372 Lyon Cedex 08, France; and 4IGFL, CNRS UMR 5242, Ecole Normale Supérieure, 46 Allée d’Italie, 69364, Lyon Cedex 08, France; *corresponding author, [email protected] J Dent Res 90(5):583-589, 2011 ABSTRACT InTRODuCTIOn Embryonic dental cells were used to check a series of criteria to be achieved for tooth engineering. -
Pediatric Oral Pathology. Soft Tissue and Periodontal Conditions
PEDIATRIC ORAL HEALTH 0031-3955100 $15.00 + .OO PEDIATRIC ORAL PATHOLOGY Soft Tissue and Periodontal Conditions Jayne E. Delaney, DDS, MSD, and Martha Ann Keels, DDS, PhD Parents often are concerned with “lumps and bumps” that appear in the mouths of children. Pediatricians should be able to distinguish the normal clinical appearance of the intraoral tissues in children from gingivitis, periodontal abnormalities, and oral lesions. Recognizing early primary tooth mobility or early primary tooth loss is critical because these dental findings may be indicative of a severe underlying medical illness. Diagnostic criteria and .treatment recommendations are reviewed for many commonly encountered oral conditions. INTRAORAL SOFT-TISSUE ABNORMALITIES Congenital Lesions Ankyloglossia Ankyloglossia, or “tongue-tied,” is a common congenital condition characterized by an abnormally short lingual frenum and the inability to extend the tongue. The frenum may lengthen with growth to produce normal function. If the extent of the ankyloglossia is severe, speech may be affected, mandating speech therapy or surgical correction. If a child is able to extend his or her tongue sufficiently far to moisten the lower lip, then a frenectomy usually is not indicated (Fig. 1). From Private Practice, Waldorf, Maryland (JED); and Department of Pediatrics, Division of Pediatric Dentistry, Duke Children’s Hospital, Duke University Medical Center, Durham, North Carolina (MAK) ~~ ~ ~ ~ ~ ~ ~ PEDIATRIC CLINICS OF NORTH AMERICA VOLUME 47 * NUMBER 5 OCTOBER 2000 1125 1126 DELANEY & KEELS Figure 1. A, Short lingual frenum in a 4-year-old child. B, Child demonstrating the ability to lick his lower lip. Developmental Lesions Geographic Tongue Benign migratory glossitis, or geographic tongue, is a common finding during routine clinical examination of children. -
Lecture 2 – Bone
Oral Histology Summary Notes Enoch Ng Lecture 2 – Bone - Protection of brain, lungs, other internal organs - Structural support for heart, lungs, and marrow - Attachment sites for muscles - Mineral reservoir for calcium (99% of body’s) and phosphorous (85% of body’s) - Trap for dangerous minerals (ex:// lead) - Transduction of sound - Endocrine organ (osteocalcin regulates insulin signaling, glucose metabolism, and fat mass) Structure - Compact/Cortical o Diaphysis of long bone, “envelope” of cuboid bones (vertebrae) o 10% porosity, 70-80% calcified (4x mass of trabecular bone) o Protective, subject to bending/torsion/compressive forces o Has Haversian system structure - Trabecular/Cancellous o Metaphysis and epiphysis of long bone, cuboid bone o 3D branching lattice formed along areas of mechanical stress o 50-90% porosity, 15-25% calcified (1/4 mass of compact bone) o High surface area high cellular activity (has marrow) o Metabolic turnover 8x greater than cortical bone o Subject to compressive forces o Trabeculae lined with endosteum (contains osteoprogenitors, osteoblasts, osteoclasts) - Woven Bone o Immature/primitive, rapidly growing . Normally – embryos, newborns, fracture calluses, metaphyseal region of bone . Abnormally – tumors, osteogenesis imperfecta, Pagetic bone o Disorganized, no uniform orientation of collagen fibers, coarse fibers, cells randomly arranged, varying mineral content, isotropic mechanical behavior (behavior the same no matter direction of applied force) - Lamellar Bone o Mature bone, remodeling of woven -
Dental Cementum Reviewed: Development, Structure, Composition, Regeneration and Potential Functions
Braz J Oral Sci. January/March 2005 - Vol.4 - Number 12 Dental cementum reviewed: development, structure, composition, regeneration and potential functions Patricia Furtado Gonçalves 1 Enilson Antonio Sallum 1 Abstract Antonio Wilson Sallum 1 This article reviews developmental and structural characteristics of Márcio Zaffalon Casati 1 cementum, a unique avascular mineralized tissue covering the root Sérgio de Toledo 1 surface that forms the interface between root dentin and periodontal Francisco Humberto Nociti Junior 1 ligament. Besides describing the types of cementum and 1 Dept. of Prosthodontics and Periodontics, cementogenesis, attention is given to recent advances in scientific Division of Periodontics, School of Dentistry understanding of the molecular and cellular aspects of the formation at Piracicaba - UNICAMP, Piracicaba, São and regeneration of cementum. The understanding of the mechanisms Paulo, Brazil. involved in the dynamic of this tissue should allow for the development of new treatment strategies concerning the approach of the root surface affected by periodontal disease and periodontal regeneration techniques. Received for publication: October 01, 2004 Key Words: Accepted: December 17, 2004 dental cementum, review Correspondence to: Francisco H. Nociti Jr. Av. Limeira 901 - Caixa Postal: 052 - CEP: 13414-903 - Piracicaba - S.P. - Brazil Tel: ++ 55 19 34125298 Fax: ++ 55 19 3412 5218 E-mail: [email protected] 651 Braz J Oral Sci. 4(12): 651-658 Dental cementum reviewed: development, structure, composition, regeneration and potential functions Introduction junction (Figure 1). The areas and location of acellular Cementum is an avascular mineralized tissue covering the afibrillar cementum vary from tooth to tooth and along the entire root surface. Due to its intermediary position, forming cementoenamel junction of the same tooth6-9. -
Effect of Posters and Mobile-Health Education Strategies on Teething Beliefs and Oral Health Knowledge Among Mothers in Nairobi
EFFECT OF POSTERS AND MOBILE-HEALTH EDUCATION STRATEGIES ON TEETHING BELIEFS AND ORAL HEALTH KNOWLEDGE AMONG MOTHERS IN NAIROBI. DR. REGINA MUTAVE JAMES REGISTRATION NUMBER: V91/96427/2014 Department of Periodontology/Community and Preventive Dentistry THESIS SUBMITTED IN FULFILMENT OF THE DOCTOR OF PHILOSOPHY DEGREE (PhD) IN COMMUNITY AND PREVENTIVE DENTISTRY, UNIVERSITY OF NAIROBI DECLARATION: I, Regina Mutave James hereby declare that this is my original work and that it has not been submitted by any other person for research purpose, degree or otherwise in any other university or institution. Signed ………………………………………. Date ………………………………. Regina Mutave James R.M.J PhD Thesis - 2015 Page i SUPERVISORS’ DECLARATION This research thesis has been submitted for the fulfillment of the requirement for the award of PhD in Community and Preventive Dentistry with our approval as supervisors. Supervisors: Signed ………………………………..Date……………………………. Prof. Loice W. Gathece BDS., MPH., PhD( Nbi). Department of Periodontology/ Community and Preventive Dentistry, University of Nairobi. Signed ………………………………..Date……………………………. Prof. Arthur M. Kemoli BDS (Nbi)., MSc (UvA)., PhD (UvA). Department of Pediatric Dentistry and Orthodontics, University of Nairobi. R.M.J PhD Thesis - 2015 Page ii DEDICATION To the Almighty, for His unending Grace! R.M.J PhD Thesis - 2015 Page iii ACKNOWLEDGEMENTS My PhD studies including this thesis were made possible by the financial support that I received from the University of Nairobi, and I am grateful for the opportunity. I wish to thank my supervisors Prof. Loice Gathece and Prof Arthur Kemoli who were always there to offer guidance and encouragement throughout the process. My sincere appreciation for my family and friends who stood by me even when I had no time for them and especially my children Erick, Aileen, Mbithe and Jynette. -
Sclerostin in Oral Tissues: Distribution, Biological Functions and Potential Therapeutic Role
Review Article Open Access Journal of Review Article Biomedical Science ISSN: 2690-487X Sclerostin in Oral Tissues: Distribution, Biological Functions and Potential Therapeutic Role Fangyuan Shuai1, Aileen To2, Yan Jing3 and Xianglong Han1* 1State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, China 2Texas A&M College of Dentistry, D3 dental student, USA 3Texas A&M College of Dentistry, Department of Orthodontics, USA ABSTRACT Sclerostin is a well-known osteogenic negative regulator whose biological functions have been widely studied in bone homeostasis. Targeting sclerostin via monoclonal antibodies was shown to be a powerful strategy for bone-related diseases. Traditionally, to osteocytes, there are other cell types in oral tissues that can produce sclerostin. Sclerostin regulates the formation of dental andsclerostin periodontal was known structures as an and osteocyte-specific is also involved inglycoprotein. various physiological However, andin recent pathological studies, events it has in been oral showntissues. thatThus, in sclerostin addition modulation has been determined as a possible treatment strategy for periodontium-related diseases. To develop the therapeutic oral tissues. In this review, we highlight the existing awareness of sclerostin’s functions in oral tissues; the roles it plays in dental and periodontalpotential of sclerostindiseases and and treatments; its antibodies and in the the therapeutic field of dentistry, potential researchers of sclerostin must and clearly its antibodies -
A Global Compendium of Oral Health
A Global Compendium of Oral Health A Global Compendium of Oral Health: Tooth Eruption and Hard Dental Tissue Anomalies Edited by Morenike Oluwatoyin Folayan A Global Compendium of Oral Health: Tooth Eruption and Hard Dental Tissue Anomalies Edited by Morenike Oluwatoyin Folayan This book first published 2019 Cambridge Scholars Publishing Lady Stephenson Library, Newcastle upon Tyne, NE6 2PA, UK British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Copyright © 2019 by Morenike Oluwatoyin Folayan and contributors All rights for this book reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission of the copyright owner. ISBN (10): 1-5275-3691-2 ISBN (13): 978-1-5275-3691-3 TABLE OF CONTENTS Foreword .................................................................................................. viii Introduction ................................................................................................. 1 Dental Development: Anthropological Perspectives ................................. 31 Temitope A. Esan and Lynne A. Schepartz Belarus ....................................................................................................... 48 Natallia Shakavets, Alexander Yatzuk, Klavdia Gorbacheva and Nadezhda Chernyavskaya Bangladesh ............................................................................................... -
Developmental Biology of Cementum
Int. J. Dev. Biol. 45: 695-706 (2001) Review Developmental Biology of Cementum THOMAS G.H. DIEKWISCH* Allan G. Brodie Laboratory for Craniofacial Genetics, University of Illinois at Chicago, USA CONTENTS Origins of cementum - a scientific "whodunit" ........................................................................695 Loss of ameloblast continuity and insertion of mesenchymal cells from the dental follicle proper ................................................................................................697 Initial cementum matrix deposition by mesenchymal cells in proximity to non-secretory epithelial cells ...................................................................................699 Cementogenesis at the tooth cervix and at the cemento-enamel junction .............................700 Early removal of HERS from the root surface in humans as seen in the Gottlieb collection ..............................................................................................701 Role of amelogenins in cementogenesis ................................................................................702 Possible mechanism of cementoblast induction .....................................................................704 Summary ................................................................................................................................704 KEY WORDS: Cementum, Hertwig’s epithelial root sheath, Gottlieb, amelogenin, periodontium Tooth cementum is a bone-like mineralized tissue secreted by Origins of cementum - a scientific -
Initiation to Eruption
Head and Neck embryology Tooth Development Review head and neckblk embryology Initiation to eruption Skip Review Initiation Initiation stomodeum Epithelial cells (dental lamina) During 6th week, ectoderm in stomodeum forms horseshoe shaped mass of oral epithelium mesenchyme Basement membrane mesenchyme Initiation of anterior primary teeth Epithelial cells in horseshoe Dental lamina begins begins the sixth to seventh week form dental lamina growing into mesenchyme of development, initiation of additional At site where tooth will be teeth follows and continues for years Dental Lamina – Initiation Supernumerary tooth PREDICT what would happen if an extra tooth was initiated. Mesiodens 1 Bud Stage – eighth week Bud Stage Epithelium (dental Lamina) Dental lamina grows down into mesenchyme at site of tooth. Mesenchyme starts to change composition in response mesenchyme PREDICT what would happen if two tooth buds fused together or one tooth bud split in half. Fusion/Gemination Cap stage – week 9 By week 9, all germ layers of future tooth have formed ElEnamel organ (ename ll)l only) Dental papilla (dentin and pulp) Fusion Gemination Dental sac (cementum, PDL, Alveolar bone) PREDICT how you would know if it was mesenchyme fusion or gemination Cap Stage Successional Dental Lamina Each primary tooth germ has epithelium a successional lamina that becomes a permanent tooth Succedaneous teeth replace a deciduous tooth, nonsuccedaneous do not IDENTIFY nonsuccedaneous teeth mesenchyme PREDICT What occurs if no successional lamina forms? 2 Congenitally -
QUICK ORAL HEALTH FACTS ABOUT the YOUNG Dr Ng Jing Jing, Dr Wong Mun Loke
ORAL health IN PRIMARY CARE UNIT NO. 2 QUICK ORAL HEALTH FACTS ABOUT THE YOUNG Dr Ng Jing Jing, Dr Wong Mun Loke ABSTRACT Table 1. Eruption sequence of Primary Dentition This article sheds light on the sequence of teeth eruption Primary Upper Teeth Primary Lower Teeth in the young and teething problems; highlights the importance and functions of the primary dentition and Central Incisors: 8-13 months Central Incisors: 6-10 months provides a quick overview of common developmental Lateral Incisors: 8-13 months Lateral Incisors: 10-16 months dental anomalies and other dental conditions in Canines: 16-23 months Canines: 16-23 months children. First Molars: 16-23 months First Molars: 13-19 months Second Molars: 25-33 months Second Molars: 23-31 months SFP2011; 37(1) Supplement : 10-13 Table 2. Eruption sequence of Adult Dentition Adult Upper Teeth Adult Lower Teeth INTRODUCTION Central Incisors: 7-8 years Central Incisors: 6-7 years The early years are always full of exciting moments as we observe Lateral Incisors: 8-9 years Lateral Incisors: 7-8 years our children grow and develop. One of the most noticeable Canines: 11-12 years Canines: 9-10 years aspects of their growth and development is the eruption of First Premolars: 10-11 years First Premolars: 10-11 years teeth. The first sign of a tooth in the mouth never fails to Second Premolars: 11-12 years Second Premolars: 11-12 years attract the attention of the parent and child. For the parent, it First Molars: 6-7 years First Molars: 6-7 years marks an important developmental milestone of the child but Second Molars: 12-13 years Second Molars: 11-13 years for the child, it can be a source of irritation brought on by the Third Molars: 18-25 years Third Molars: 18-25 years whole process of teething. -
Current and Future Trends in Periodontal Tissue Engineering and Bone Regeneration
Galli et al. Plast Aesthet Res 2021;8:3 Plastic and DOI: 10.20517/2347-9264.2020.176 Aesthetic Research Review Open Access Current and future trends in periodontal tissue engineering and bone regeneration Matthew Galli1, Yao Yao1, William V. Giannobile1,2,3, Hom-Lay Wang1 1Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USA. 2Biointerfaces Institute, North Campus Research Complex, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USA. 3Harvard School of Dental Medicine, Boston, MA 02115, USA. Correspondence to: Prof. Hom-Lay Wang, Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, 1011 North University Avenue, Ann Arbor, MI 48109, USA. E-mail: [email protected] How to cite this article: Galli M, Yao Y, Giannobile WV, Wang HL. Current and future trends in periodontal tissue engineering and bone regeneration. Plast Aesthet Res 2021;8:3. http://dx.doi.org/10.20517/2347-9264.2020.176 Received: 31 Aug 2020 First Decision: 16 Nov 2020 Revised: 28 Nov 2020 Accepted: 7 Dec 2020 Published: 8 Jan 2021 Academic Editor: Filippo Citterio, Raúl González-García Copy Editor: Cai-Hong Wang Production Editor: Jing Yu Abstract Periodontal tissue engineering involves a multi-disciplinary approach towards the regeneration of periodontal ligament, cementum and alveolar bone surrounding teeth, whereas bone regeneration specifically applies to ridge reconstruction in preparation for future implant placement, sinus floor augmentation and regeneration of peri- implant osseous defects. Successful periodontal regeneration is based on verifiable cementogenesis on the root surface, oblique insertion of periodontal ligament fibers and formation of new and vital supporting bone. -
It's Only Teething…
OPINION personal view It’s only teething… A report of the myths and modern approaches to teething M. P. Ashley1 Paediatric dentistry is not my usual field of work. I am now based ter, come off best’. Gastrointestinal disorders and contamination of foodstuffs were more almost entirely in restorative dentistry and it is five years since I frequent in the summer. worked in the dental department of a children’s hospital. An essay In medieval times, animal substances on teething would appear to be an unusual choice of topic. With the were still being rubbed into the gums and current professional climate of ‘general professional education’ and teething infants were encouraged to chew ‘lifelong learning’ I can easily justify my time and effort studying a on hard objects such as roots. In 1429, Von Louffenberg, a German priest, summarised subject somewhat removed from my regular work. However, to be the care of a teething baby. completely honest, I have reached that age when many of my ‘Now when your baby’s teeth appear, you friends, relatives and colleagues are enjoying the sleepless nights must of these take prudent care. that accompany expanding families. Add to this the fact that I have For teething comes with grievous pain, so recently married into a family of midwives, health visitors, nurses to my word take heed again. When now the teeth are pushing and new mothers. I was not sure that I was giving the best, most up through, to rub the gums thou thus shall to date advice when asked about teething.