Rift Valley Lake Fish and Shellfish Provided Brain-Specific Nutrition for Early Homo
Total Page:16
File Type:pdf, Size:1020Kb
Downloaded from British Journal of Nutrition (1998), 79, 3-21 3 https://www.cambridge.org/core Review article Rift Valley lake fish and shellfish provided brain-specific nutrition for early Homo . IP address: C. Leigh Broadhurst'*t, Stephen C. Cunnane2 and Michael A. Crawford3 122"d Century Nutrition Inc., 1315 Harding Lane, Cloverly, MD 209054007, USA and Visiting Scientist, Nutrient 170.106.40.219 Requirements and Functions Laboratory, Building 307, Room 224, USDA Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA 2Department of Nutritional Sciences, Faculty of Medicine, FitzGerald Building, 150 College Street, University of Toronto, Toronto, Ontario M5S IA8, Canada , on 31nstitute of Brain Chemistry and Human Nutrition, University of North London, 166-222 Holloway Road, 23 Sep 2021 at 17:29:05 London N78DB, UK (Received 3 January 1997 - Revised 2 September 1997 - Accepted 3 September 1997) , subject to the Cambridge Core terms of use, available at An abundant, balanced dietary intake of long-chain polyunsaturated fatty acids is an absolute requirement for sustaining the very rapid expansion of the hominid cerebral cortex during the last one to two million years. The brain contains 600 g lipid/kg, with a long-chain poly- unsaturated fatty acid profile containing approximately equal proportions of arachidonic acid and docosahexaenoic acid. Long-chain polyunsaturated fatty acid deficiency at any stage of fetal and/or infant development can result in irreversible failure to accomplish specific components of brain growth. For the past fifteen million years, the East African Rift Valley has been a unique geological environment which contains many enormous freshwater lakes. Paleoan- thropological evidence clearly indicates that hominids evolved in East Africa, and that early Homo inhabited the Rift Valley lake shores. Although earlier hominid species migrated to Eurasia, modem Homo supiens is believed to have originated in Africa between 100 and 200 thousand years ago, and subsequently migrated throughout the world. A shift in the hominid resource base towards more high-quality foods occurred approximately two million years ago; this was accompanied by an increase in relative brain size and a shift towards modem patterns of fetal and infant development. There is evidence for both meat and fish scavenging, although sophisticated tool industries and organized hunting had not yet developed. The earliest https://www.cambridge.org/core/terms occurrences of modem H. supiens and sophisticated tool technology are associated with aquatic resource bases. Tropical freshwater fish and shellfish have long-chain polyunsaturated lipid ratios more similar to that of the human brain than any other food source known. Consistent consumption of lacustrine foods could have provided a means of initiating and sustaining cerebral cortex growth without an attendant increase in body mass. A modest intake of fish and shellfish (6-12 % total dietary energy intake) can provide more arachidonic acid and especially more docosahexaenoic acid than most diets contain today. Hence, 'brain-specific' nutrition had and still has significant potential to affect hominid brain evolution. Fish: Brain-specific nutrition: Long-chain PUFA: East Africa Rift Valley Lakes . https://doi.org/10.1079/BJN19980004 Marked expansion of the hominid cerebral cortex took gical and ecological environment of the East African Rift place only in the last one to two million years. During this Valley provided an equally unique nutritional resource base small evolutionary window, genus Australopithecus be- for the enlargement of the Homo brain, culminating in came extinct while Homo greatly expanded. Sophisticated Homo sapiens. How in this remarkably short stretch of tool manufacture, organized hunting, culture, and speech evolutionary history did our intelligence arise? While many followed rapidly. We hypothesize that the unique geolo- physical (i.e. development of bipedalism, speech), ecolo- Abbreviations: AA, arachidonic acid; CNS, central nervous system; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; EQ, encephalization quotient; FD, high-fish mixed-diet population group; LA, linoleic acid; LC-PUFA, long-chain PUFA; LNA, a-linolenic acid; PUFA, polyunsaturated fatty acids; VD, vegetarian-diet population group. *Corresponding author: Dr C. Leigh Broadhurst, email [email protected] ?Author is not USDA employee. Downloaded from 4 C. L. Broadhurst et al. gical (adaptation to omnivorous diet, drier climatic condi- to lie between. We envision something such as: horninids https://www.cambridge.org/core tions) and cultural adaptations (use of tools, living in scavenged fish and/or fished opportunistically, which groups) have roles, these adaptations alone are apparently helped increase intelligence enough for them to fish more not sufficient to account for the unique intelligence and often and more successfully. We aim to bring attention to culture we have today. If these adaptations alone were the fact that the latter end-member, in which nutrition plays sufficient, then in all cases we must ask ourselves why no a crucial role in the origin and maintenance of intelligence, other primates developed as such. has not been given adequate consideration. Previous authors (Martin, 1983; Harvey & Clutton- Brock, 1985; Blumenschine, 1991; Foley & Lee, 1991; . IP address: McHenry, 1994) have considered an ecological approach to human evolution. In these arguments, the high metabolic Encephalization quotients (EQ): quantifying cerebral energy requirements of the brain require that hominids expansion 170.106.40.219 must have accessed relatively-high-quality and abundant The term EQ was introduced in the 1970s to account for the food resources. Various selective pressures affecting influence of body size on brain size, thereby permitting a hominid evolution might be necessary, but are not scale of comparison between species that would identify sufficient conditions for cerebral expansion. Whatever the relatively larger-brained species independent of body size , on selective pressures, they can only be satisfied in a context (Martin, 1983). The EQ compares brain weight : overall 23 Sep 2021 at 17:29:05 where sufficient dietary energy and essential nutrients are body weight for all species of interest, and is scaled so that available to fuel the added brain growth. Sufficient protein, the comparison among brains is in effect done for constant vitamins, and trace elements are certainly required, but body size. It has become a valuable tool for quantifying the dletary essential polyunsaturated fatty acids (PUFA) are remarkably larger brain size in H. sapiens v. other extant probably the most limiting nutrients for neural growth primate and extinct hominoid species (Table 1). By (Crawford & Sinclair, 1972). If hominid diets were providing a quantitative and reproducible scale, the EQ , subject to the Cambridge Core terms of use, available at consistently deficient in long-chain (LC-) PUFA, the has helped evolutionists focus on developing an adequate uniquely complex human neurological system could not explanation for the enlargement of the evolving human have developed, regardless of the diverse stimuli that may brain. Exact EQ values vary among sources, depending on have been involved. the method of calculation and the database used; however, We are in agreement with the ecological approach to all sources consistently show that adult H. sapiens has an evolution of human intelligence, and propose that nutrition EQ about 2.4-2.7 times larger than adult Pan troglodytes played a more crucial role in the rapid neural development (modem chimpanzee). They also consistently show that as of genus Homo than has been considered previously. We hominids evolved, EQ increased from about 1.4 in concentrate specifically on the nutrition provided by the Australopithecus africanus to about 2..4 in Homo erectus. unique ecosystem of the East African Rift Valley lakes. EQ values are not as different between neonates of The fossil evidence clearly indicates that Homo arose in the various primate species as they are between adults, vicinity of these lakes, which are geologically better suggesting that both brain and body growth postnatally classified as ‘proto-oceans’. The diverse alkaline-fresh- have an influence on the resultant EQ of adults. It should be water fish species within those lakes provided, either noted that overall body weight is still a key reference point directly or indirectly, a source of both protein and PUFA. In for establishing EQ values, and modem-day primates are https://www.cambridge.org/core/terms particular, the freshwater-fish lipid profile has a docosa- significantly leaner than humans. Hence, the presence of hexaenoic acid (DHA) : arachidonic acid (AA) value that is 15-30 % body fat in humans actually reduces the EQ closer to that in our brain phospholipids than any other food difference between primates (or hominids) and H. sapiens. source known. We hypothesize that consistent consumption This is especially true for neonates, since human infants of fish, crustaceans, molluscs, and other lacustrine species have much more body fat than infants of other primate from the lake margins provided a facile means of both species. initiating and sustaining growth of the cerebral cortex without an attendant increase in body mass. Table 1. Mean brain volumes and encephalization quotients (brain We are aware that the origin of human intelligence is one weight : overall body weight; EQ)