Alister Mcgrath
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The Impact of NMR and MRI
WELLCOME WITNESSES TO TWENTIETH CENTURY MEDICINE _____________________________________________________________________________ MAKING THE HUMAN BODY TRANSPARENT: THE IMPACT OF NUCLEAR MAGNETIC RESONANCE AND MAGNETIC RESONANCE IMAGING _________________________________________________ RESEARCH IN GENERAL PRACTICE __________________________________ DRUGS IN PSYCHIATRIC PRACTICE ______________________ THE MRC COMMON COLD UNIT ____________________________________ WITNESS SEMINAR TRANSCRIPTS EDITED BY: E M TANSEY D A CHRISTIE L A REYNOLDS Volume Two – September 1998 ©The Trustee of the Wellcome Trust, London, 1998 First published by the Wellcome Trust, 1998 Occasional Publication no. 6, 1998 The Wellcome Trust is a registered charity, no. 210183. ISBN 978 186983 539 1 All volumes are freely available online at www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/ Please cite as : Tansey E M, Christie D A, Reynolds L A. (eds) (1998) Wellcome Witnesses to Twentieth Century Medicine, vol. 2. London: Wellcome Trust. Key Front cover photographs, L to R from the top: Professor Sir Godfrey Hounsfield, speaking (NMR) Professor Robert Steiner, Professor Sir Martin Wood, Professor Sir Rex Richards (NMR) Dr Alan Broadhurst, Dr David Healy (Psy) Dr James Lovelock, Mrs Betty Porterfield (CCU) Professor Alec Jenner (Psy) Professor David Hannay (GPs) Dr Donna Chaproniere (CCU) Professor Merton Sandler (Psy) Professor George Radda (NMR) Mr Keith (Tom) Thompson (CCU) Back cover photographs, L to R, from the top: Professor Hannah Steinberg, Professor -
Postmaster & the Merton Record 2020
Postmaster & The Merton Record 2020 Merton College Oxford OX1 4JD Telephone +44 (0)1865 276310 Contents www.merton.ox.ac.uk College News From the Warden ..................................................................................4 Edited by Emily Bruce, Philippa Logan, Milos Martinov, JCR News .................................................................................................8 Professor Irene Tracey (1985) MCR News .............................................................................................10 Front cover image Merton Sport .........................................................................................12 Wick Willett and Emma Ball (both 2017) in Fellows' Women’s Rowing, Men’s Rowing, Football, Squash, Hockey, Rugby, Garden, Michaelmas 2019. Photograph by John Cairns. Sports Overview, Blues & Haigh Ties Additional images (unless credited) Clubs & Societies ................................................................................24 4: © Ian Wallman History Society, Roger Bacon Society, Neave Society, Christian 13: Maria Salaru (St Antony’s, 2011) Union, Bodley Club, Mathematics Society, Quiz Society, Art Society, 22: Elina Cotterill Music Society, Poetry Society, Halsbury Society, 1980 Society, 24, 60, 128, 236: © John Cairns Tinbergen Society, Chalcenterics 40: Jessica Voicu (St Anne's, 2015) 44: © William Campbell-Gibson Interdisciplinary Groups ...................................................................40 58, 117, 118, 120, 130: Huw James Ockham Lectures, History of the Book -
Postmaster & the Merton Record 2017
Postmaster & The Merton Record 2017 Merton College Oxford OX1 4JD Telephone +44 (0)1865 276310 www.merton.ox.ac.uk Contents College News Features Records Edited by Merton in Numbers ...............................................................................4 A long road to a busy year ..............................................................60 The Warden & Fellows 2016-17 .....................................................108 Claire Spence-Parsons, Duncan Barker, The College year in photos Dr Vic James (1992) reflects on her most productive year yet Bethany Pedder and Philippa Logan. Elections, Honours & Appointments ..............................................111 From the Warden ..................................................................................6 Mertonians in… Media ........................................................................64 Six Merton alumni reflect on their careers in the media New Students 2016 ............................................................................ 113 Front cover image Flemish astrolabe in the Upper Library. JCR News .................................................................................................8 Merton Cities: Singapore ...................................................................72 Undergraduate Leavers 2017 ............................................................ 115 Photograph by Claire Spence-Parsons. With MCR News .............................................................................................10 Kenneth Tan (1986) on his -
Glycobiology at Oxford a Personal View
feature Glycobiology Glycobiology at Oxford A personal view by Raymond Dwek In the 1980s, one of the approaches we took to determining the One day, I received a knock on my (Oxford Glycobiology function of oligosaccharides was to find out how they altered in door from a woman working for the Institute, UK) disease states. In 1985 my research group published a paper in Oxford English Dictionary. She Nature in which we showed that a change in the glycosylation informed me that she was responsible of the antibody molecule correlated with the occurrence of for the letter ‘G’. Glycobiology had rheumatoid arthritis. When I was interviewed on the Radio 4 been chosen, after much discussion Today programme and by other radio stations, it became clear and deliberations, to be included in the that the word ‘oligosaccharide’ was not user-friendly for the vast new addendum to the dictionary, majority of the non-scientific public. I coined the word which was to be published in 1992. I ‘glycobiology’, and, with Tom Rademacher and Raj Parekh, members subsequently attended a launch of the of my research team, subsequently used it in the Annual Reviews of supplement to the Oxford English Biochemistry in 19881. At that time I was appointed Professor of Dictionary and was assured by the Glycobiology by Oxford University and encouraged the Oxford Vice Chancellor of Oxford University University Press to start the journal Glycobiology. The word that there was no higher honour for a ‘glycobiology’ was soon taken up around the world, where it scientist than to have his name and his provided a special identity to many people already working in the word in so eminent a publication as field. -
History of UK Biobank, Electronic Medical Records in the NHS, and the Proposal for Data-Sharing Without Consent
Bioscience for Life? Appendix A The history of UK Biobank, electronic medical records in the NHS, and the proposal for data-sharing without consent January 2009 1 Bioscience for Life? Appendix A Table of contents 1. Introduction................................................................... 12 2. Summary........................................................................ 12 3. What is UK Biobank?...................................................... 13 4. Concerns about UK Biobank and genetic ‘prediction and prevention’ of disease........................................................ 14 5. Timeline......................................................................... 15 1995................................................................................... 15 The Foresight report................................................................................ 15 1997................................................................................... 16 The biotech economy......................................................... 16 The European directive and gene patenting........................17 A new NHS........................................................................ 17 1998.................................................................................. 17 Claims that genetics will transform medicine.................... 17 The Government partners with the Wellcome Trust........... 18 The McKinsey Report......................................................... 18 An increasing role for the Wellcome Trust........................ -
Sixth Report
HOUSE OF LORDS SELECT COMMITTEE ON SCIENCE AND TECHNOLOGY - SIXTH REPORT The published report was ordered by the House of Lords to be printed 21 November 2000. CONTENTS REPORT SUMMARY CHAPTER 1: INTRODUCTION CHAPTER 2: DISCIPLINES EXAMINED CHAPTER 3: PATIENT SATISFACTION, THE ROLE OF THE THERAPIST AND THE PLACEBO RESPONSE CHAPTER 4: EVIDENCE CHAPTER 5: REGULATION CHAPTER 6: PROFESSIONAL TRAINING AND EDUCATION CHAPTER 7: RESEARCH AND DEVELOPMENT CHAPTER 8: INFORMATION CHAPTER 9: DELIVERY SUMMARY OF RECOMMENDATIONS APPENDIX 1 Difficulties of Randomised Controlled Trials APPENDIX 2 Features of the General Osteopathic Council and the General Chiropractic Council APPENDIX 3 Visit to Mr Simon Mills' CAM Practice, Department of Complementary Medicine, University of Exeter; and the Centre for Complementary Health Studies, University of Exeter On 22/23 March 2000 APPENDIX 4 Visit to the Marylebone Health Centre, 12 April 2000 APPENDIX 5 Visit to the University of Southampton Medical School and the Centre for the Study of Complementary Medicine, Southampton, on 9 June 2000 APPENDIX 6 Special visit to the Glasgow Homeopathic Hospital by two members of the Sub-Committee on 24 August 2000 APPENDIX 7 Sub-Committee 1 APPENDIX 8 List of Witnesses APPENDIX 9 Acronyms Note Written and oral evidence received by the Committee is published in two separate volumes (HL Paper 48 and HL Paper 118). In the text of the Report: Q refers to a question in oral evidence; p refers to a page of written evidence printed in HL Paper 118; and P refers to a page of written evidence printed in HL Paper 48. By the Select Committee appointed to consider Science and Technology. -
Postmaster & the Merton Record 2018
Postmaster & The Merton Record 2018 Merton College Oxford OX1 4JD Telephone +44 (0)1865 276310 www.merton.ox.ac.uk Contents College News Edited by Claire Spence-Parsons, Duncan Barker, James Vickers, From the Warden ..................................................................................4 Timothy Foot (2011), and Philippa Logan. JCR News .................................................................................................6 Front cover image MCR News ...............................................................................................8 Oak and ironwork detail on the thirteenth-century Merton Sport ........................................................................................10 Hall door. Photograph by John Cairns. American Football, Hockey, Tennis, Men’s Rowing, Women’s Rowing, Rugby, Badminton, Water Polo, Sports Overview, Additional images (unless credited) Blues & Haigh Awards 4, 12, 15, 38, 39, 42, 44, 47, 56, 62, 68, 70, 102, 104, 105, Clubs & Societies ................................................................................22 107, 113, 117, 119, 125, 132: John Cairns Merton Floats, Bodley Club, Chalcenterics, Mathematics Society, (www.johncairns.co.uk) Halsbury Society, History Society, Tinbergen Society, Music Society, 6: Dan Paton (www.danpaton.net) Neave Society, Poetry Society, Roger Bacon Society 8, 9, 34, 124: Valerian Chen (2016) 14, 16, 17, 22, 23, 27, 28: Sebastian Dows-Miller (2016) Interdisciplinary Groups ....................................................................34 -
The Royal College of Physicians and Oxford Brookes University Medical Sciences Video Archive MSVA 036
© 2011 Oxford Brookes University The Royal College of Physicians and Oxford Brookes University Medical Sciences Video Archive MSVA 036 Sir Rex Richards FRS in interview with Max Blythe Oxford, March 1988 Interview Two MB Sir Rex, in the closing minutes of our last interview, we had you returning in 1955 from America working with Purcell 1 and then Pound, 2 and then moving progressively on to various interests with magnets, electromagnets, and then moving towards the 1960s and changes in interests, and also a meeting with Martin Wood – we’d just mentioned, I think, at the close of the interview – that was going to be quite significant. RR Yes, indeed. Yes. Well, you see, at the end of the… by the late 1950s when high-resolution magnetic resonance had become quite well-established by then, although the equipment was still rather primitive, but my high-resolution permanent magnet instrument was behaving very well, and it was very productive in exploring the use of NMR [nuclear magnetic resonance] to study the structures of organic compounds of modest size. MB This is the magnet made by Mullard? RR Mullard. Yes, that’s the magnet made by Mullard. And from that time onwards, this technique of high-resolution NMR was exploited; commercial equipment was manufactured by one or two major international manufacturers, and it has, of course, become a technique of immense importance in the organic chemical and pharmaceutical industry. It is the method of choice for obtaining the structures of organic compounds. 1 Professor Edward Mills Purcell (1912-1997), Professor of Physics at Harvard University, 1949-77. -
Makers of Modern Biomedicine: a Register
MAKERS OF MODERN BIOMEDICINE: A REGISTER Compiled by C Overy, A Wilkinson, and E M Tansey Volume 63 2017 ©The Trustee of the Wellcome Trust, London, 2017 First published by Queen Mary University of London, 2017 The History of Modern Biomedicine Research Group is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 1 91019 5307 All volumes are freely available online at www.histmodbiomed.org Please cite as: Overy C, Wilkinson A, Tansey E M. (comps) (2017) Makers of Modern Biomedicine: A Register. Wellcome Witnesses to Contemporary Medicine, vol. 63. London: Queen Mary University of London. CONTENTS Introduction E M Tansey v Acknowledgements E M Tansey vii Witness Seminar volume titles ix Contributors to Witness Seminars and interviews 1 Images 61 INTRODUCTION In 1997 we published the proceedings of our first four Witness Seminars in modern medicine, funded by the Wellcome Trust. Somewhat optimistically, we called this ‘volume 1’, hoping that we might get funding and support to develop the series at least into double figures. After twenty years of generous funding, we have now published 62 volumes, containing the proceedings of 70 or so seminars, all of which are made freely available on the web. The themes represented here were selected by a Programme Committee (until 2010) or were related to a Strategic Award from the Wellcome Trust (from 2010 until 2017). Topics cover the whole range of modern biomedicine: from clinical genetics to medical- and bio-technology; ethics to rural practice; pure lab research to clinical care; narrative medicine to neuroscience. Our meetings have attracted more than 1200 individuals who have contributed their recollections and comments, agreements and disagreements; several of them having contributed in multiple ways: attending or chairing a number of meetings, writing introductions to the published proceedings, providing commentaries and appendices. -
A Contemporary History of the Origins and Development of UK Biobank 1998-2005
A contemporary history of the origins and development of UK Biobank 1998-2005 Mairi Anna Langan A dissertation submitted in partial fulfilment of the degree of PhD University of Glasgow MRC Social and Public Health Sciences Unit August, 2007 © Mairi Langan, 2007 1 Abstract Background This thesis examines the origins and early development of UK Biobank. This is a resource funded in 2002 by the Medical Research Council, the Wellcome Trust, the Department of Health and the Scottish Executive to gather genetic and lifestyle information from half a million participants aged 40-69 years old in the UK and monitor their health for up to thirty years in order to improve the prevention, diagnosis and treatment of major diseases. UK Biobank was set up following the completion of the Human Genome Project in 2001, and was one of many established at around the same time with the goal of translating the knowledge of the human genome sequence into practical benefits for human health. (National genetic databases were also set up or proposed in Iceland, Estonia, Latvia, Sweden, Singapore, Tonga, Spain, and the United States). They, and the Human Genome Project, had raised a number of important issues about access to and ownership of genetic information. Aims The original aim of my PhD was to examine lay and professional understandings and responses to Biobank in the light of this background. However, UK Biobank took longer than expected to reach the stage of data collection, in part because of negotiations about its organisational structure. The aim therefore changed to address the question of how and why was UK Biobank initially configured in the manner it was.