Evolution and Postglacial Colonization of Seewis Hantavirus with Sorex Araneus in Finland
Infection, Genetics and Evolution 57 (2018) 88–97 Contents lists available at ScienceDirect Infection, Genetics and Evolution journal homepage: www.elsevier.com/locate/meegid Research paper Evolution and postglacial colonization of Seewis hantavirus with Sorex T araneus in Finland ⁎ Jiaxin Linga, , Teemu Smuraa, Daniel Tamaritb, Otso Huituc, Liina Voutilainena,d, Heikki Henttonend, Antti Vaheria, Olli Vapalahtia,e,f, Tarja Sironena,e a University of Helsinki, Medicum, Department of Virology, Helsinki, Finland b Uppsala University, Biomedical Centre, Science for Life Laboratory, Cell and Molecular Biology, Department of Molecular Evolution, Sweden c Forest and Animal Ecology, Natural Resources Institute Finland, Tampere, Finland d Forest and Animal Ecology, Natural Resources Institute Finland, Helsinki, Finland e University of Helsinki, Department of Veterinary Biosciences, Helsinki, Finland f Helsinki University Hospital, University of Helsinki, Helsinki, Finland ARTICLE INFO ABSTRACT Keywords: Hantaviruses have co-existed with their hosts for millions of years. Seewis virus (SWSV), a soricomorph-borne Hantavirus hantavirus, is widespread in Eurasia, ranging from Central Siberia to Western Europe. To gain insight into the Seewis phylogeography and evolutionary history of SWSV in Finland, lung tissue samples of 225 common shrews (Sorex Sorex araneus araneus) trapped from different parts of Finland were screened for the presence of SWSV RNA. Forty-two of the Evolution samples were positive. Partial small (S), medium (M) and large (L) segments of the virus were sequenced, and Phylogeography analyzed together with all SWSV sequences available in Genbank. The phylogenetic analysis of the partial S- segment sequences suggested that all Finnish SWSV strains shared their most recent common ancestor with the Eastern European strains, while the L-segment suggested multiple introductions.
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