CORE Metadata, citation and similar papers at core.ac.uk Provided by epublications@Marquette Marquette University e-Publications@Marquette Chemistry Faculty Research and Publications Chemistry, Department of 8-1-2009 Recent Applications of Acyclic (Diene)iron Complexes and (Dienyl)iron Cations in Organic Synthesis William Donaldson Marquette University,
[email protected] Subhabrata Chaudhury Marquette University Accepted version. European Journal of Organic Chemistry, Volume 2009, Issue 23 (August 2009). pp 3831-3843. DOI: 10.1002/ejoc.200900141 © 2009 Wiley-VCH Verlag. Used with permission. This is the pre-peer reviewed version of the article, which has been published in final form. NOT THE PUBLISHED VERSION; this is the author’s final, peer-reviewed manuscript. The published version may be accessed by following the link in the citation at the bottom of the page. Recent Applications of Acyclic (Diene)iron Complexes and (Dienyl)iron Cations in Organic Synthesis William A. Donaldson Department of Chemistry, Marquette University Milwaukee, WI Subhabrata Chaudhury Department of Chemistry, Marquette University Milwaukee, WI Abstract: Complexation of (tricarbonyl)iron to an acyclic diene serves to protect the ligand against oxidation, reduction and cycloaddition reactions while the steric bulk of this adjunct serves to direct the approach reagents to unsaturated groups attached to the diene onto the face opposite to iron. Furthermore, the Fe(CO)3 moiety can serve to stabilize carbocation centers adjacent to the diene (i.e. pentadienyl-iron cations). Recent applications of these reactivities to the synthesis of polyene, cyclopropane, cycloheptadiene and cyclohexenone containing natural products or analogs will be presented. Keywords: Diene ligands, Iron, Synthetic methods, Regioselective nucleophilic addition.