The Rise and Fall of the Tuberculosis Sanitarium in Response to the White Plague a Thesis Submitted to the Graduate School In
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Remedy and Elimination of Tuberculosis” Akanksha Mishra [email protected]
The University of San Francisco USF Scholarship: a digital repository @ Gleeson Library | Geschke Center Master's Theses Theses, Dissertations, Capstones and Projects Winter 12-15-2017 A Novel Model of “Remedy and Elimination of Tuberculosis” Akanksha Mishra [email protected] Follow this and additional works at: https://repository.usfca.edu/thes Part of the Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons, Diseases Commons, Epidemiology Commons, International Public Health Commons, and the Other Medicine and Health Sciences Commons Recommended Citation Mishra, Akanksha, "A Novel Model of “Remedy and Elimination of Tuberculosis”" (2017). Master's Theses. 1118. https://repository.usfca.edu/thes/1118 This Thesis is brought to you for free and open access by the Theses, Dissertations, Capstones and Projects at USF Scholarship: a digital repository @ Gleeson Library | Geschke Center. It has been accepted for inclusion in Master's Theses by an authorized administrator of USF Scholarship: a digital repository @ Gleeson Library | Geschke Center. For more information, please contact [email protected]. A Novel Model of “Remedy and Elimination of Tuberculosis” By: Akanksha Mishra University of San Francisco November 21, 2017 MASTER OF ARTS in INTERNATIONAL STUDIES 1 ABSTRACT OF THE DISSERTATION A Novel Model of “Remedy and Elimination of Tuberculosis” MASTER OF ARTS in INTERNATIONAL STUDIES By AKANKSHA MISHRA December 18, 2017 UNIVERSITY OF SAN FRANCISCO Under the guidance and approval of the committee, and approval by all the members, this thesis project has been accepted in partial fulfillment of the requirements for the degree. Adviser__________________________________ Date ________________________ Academic Director Date ________________________________________ ______________________ 2 ABSTRACT Tuberculosis (TB), is one of the top ten causes of death worldwide. -
Media Inquiries
2010 WORLD MONUMENTS FUND/KNOLL MODERNISM PRIZE AWARDED TO BIERMAN HENKET ARCHITECTEN AND WESSEL DE JONGE ARCHITECTEN Award given for restoration of Zonnestraal Sanatorium, in Hilversum, The Netherlands; rescue of iconic building helped launch global efforts to preserve modern architecture at risk. For Immediate Release—New York, NY, October 5, 2010. Bonnie Burnham, president, World Monuments Fund (WMF), announced today that WMF has awarded its 2010 World Monuments Fund/Knoll Modernism Prize to Bierman Henket architecten and Wessel de Jonge architecten, leading practitioners in the restoration of modern buildings, for their technically and programmatically exemplary restoration of the Zonnestraal Sanatorium (designed 1926–28; completed 1931), in Hilversum, The Netherlands. The sanatorium is a little-known but iconic modernist building designed by Johannes Duiker (1890–1935) and Bernard Bijvoet (1889–1979). The biennial award will Zonnestraal, Main Pavilion, 2004 (post-restoration). Photo courtesy Bierman Henket architecten and Wessel de Jonge architecten. be presented to the Netherlands- based firms at The Museum of Modern Art, New York (MoMA), on November 18, 2010, by Ms. Burnham; Barry Bergdoll, MoMA’s Philip Johnson Chief Curator of Architecture & Design and chairman of the Prize jury; and Andrew Cogan, CEO, Knoll, Inc. The presentation will be followed by a free public lecture by Messrs. Henket and de Jonge, who will accept the award on behalf of their firms. The World Monuments Fund/Knoll Modernism Prize is the only prize to acknowledge the specific and growing threats facing significant modern buildings, and to recognize the architects and designers who help ensure their rejuvenation and long-term survival through new design solutions. -
Paimio Sanatorium
MARIANNA HE IKINHEIMO ALVAR AALTO’S PAIMIO SANATORIUM PAIMIO AALTO’S ALVAR ARCHITECTURE AND TECHNOLOGY ARCHITECTURE AND TECHNOLOGY: : PAIMIO SANATORIUM ARCHITECTURE AND TECHNOLOGY: Alvar Aalto’s Paimio Sanatorium TIIVISTELMÄ rkkitehti, kuvataiteen maisteri Marianna Heikinheimon arkkitehtuurin histo- rian alaan kuuluva väitöskirja Architecture and Technology: Alvar Aalto’s Paimio A Sanatorium tarkastelee arkkitehtuurin ja teknologian suhdetta suomalaisen mestariarkkitehdin Alvar Aallon suunnittelemassa Paimion parantolassa (1928–1933). Teosta pidetään Aallon uran käännekohtana ja yhtenä maailmansotien välisen moder- nismin kansainvälisesti keskeisimpänä teoksena. Eurooppalainen arkkitehtuuri koki tuolloin valtavan ideologisen muutoksen pyrkiessään vastaamaan yhä nopeammin teollis- tuvan ja kaupungistuvan yhteiskunnan haasteisiin. Aalto tuli kosketuksiin avantgardisti- arkkitehtien kanssa Congrès internationaux d’architecture moderne -järjestön piirissä vuodesta 1929 alkaen. Hän pyrki Paimion parantolassa, siihenastisen uransa haastavim- massa työssä, soveltamaan uutta näkemystään arkkitehtuurista. Työn teoreettisena näkökulmana on ranskalaisen sosiologin Bruno Latourin (1947–) aktiivisesti kehittämä toimijaverkkoteoria, joka korostaa paitsi sosiaalisten, myös materi- aalisten tekijöiden osuutta teknologisten järjestelmien muotoutumisessa. Teorian mukaan sosiaalisten ja materiaalisten toimijoiden välinen suhde ei ole yksisuuntainen, mikä huo- mio avaa kiinnostavia näkökulmia arkkitehtuuritutkimuksen kannalta. Olen ymmärtänyt arkkitehtuurin -
Planning the Nation: the Sanatorium Movement In
This article was downloaded by: [University College London] On: 11 March 2015, At: 05:23 Publisher: Routledge Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH, UK The Journal of Architecture Publication details, including instructions for authors and subscription information: http://www.tandfonline.com/loi/rjar20 Planning the Nation: the sanatorium movement in Germany Eva Eylersa a The Bartlett School of Architecture, University College London, United Kingdom Published online: 23 Oct 2014. Click for updates To cite this article: Eva Eylers (2014) Planning the Nation: the sanatorium movement in Germany, The Journal of Architecture, 19:5, 667-692, DOI: 10.1080/13602365.2014.966587 To link to this article: http://dx.doi.org/10.1080/13602365.2014.966587 PLEASE SCROLL DOWN FOR ARTICLE Taylor & Francis makes every effort to ensure the accuracy of all the information (the “Content”) contained in the publications on our platform. Taylor & Francis, our agents, and our licensors make no representations or warranties whatsoever as to the accuracy, completeness, or suitability for any purpose of the Content. Versions of published Taylor & Francis and Routledge Open articles and Taylor & Francis and Routledge Open Select articles posted to institutional or subject repositories or any other third-party website are without warranty from Taylor & Francis of any kind, either expressed or implied, including, but not limited to, warranties of merchantability, fitness for a particular purpose, or non-infringement. Any opinions and views expressed in this article are the opinions and views of the authors, and are not the views of or endorsed by Taylor & Francis. -
Word Heritage Papers 5 ; Identification and Documentation of Modern
World Heritage papers5 Identification and Documentation of Modern Heritage Identification and Documentation of Modern Heritage Disclaimer The authors are responsible for the choice and presentation of the facts contained in this publication and for the opinions therein, which are not necessarily those of UNESCO and do not commit the Organization. The designation employed and the presentation of the material throughout this publication do not imply the expression of any opinion whatsoever on the part of UNESCO concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Published in 2003 by the UNESCO World Heritage Centre with financial contribution from the Netherlands Funds-in-Trust 7, place de Fontenoy 75352 Paris 07 SP France Tel : 33 (0)1 45 68 18 76 Fax : 33 (0)1 45 68 55 70 E-mail : [email protected] http://whc.unesco.org Compiled and edited by R. van Oers and S. Haraguchi Foreword Under the Global Strategy for a credible, balanced and representative World Heritage List, adopted by the World Heritage Committee in 1994, the World Heritage Centre is engaged in assisting States Parties that have few or no World Heritage sites to protect, preserve and nominate their heritage of outstanding universal value. Next to this, a pro-active approach is also taken with regard to the identification and documentation of less-represented categories of heritage for inclusion on the World Heritage List. One such category is Modern Heritage, which comprises the architecture, town planning and landscape design of the 19th and 20th centuries. -
Open Corner Loggias Tested Key Interventions That Were Damaging to the Physical Fabric
World Monuments Fund/ Knoll Modernism Prize 2016 AWARD TO Molenaar & Co. architecten, Hebly Theunissen architecten, and Michael van Gessel landscapes For the rehabilitation of the Justus van Effen complex in Rotterdam, the Netherlands Designed and built by Michiel Brinkman 1919-1922 1 Jury Citation The 2016 World Monuments Fund/Knoll Modernism Prize is awarded to Molenaar and Co. architecten, Rotterdam; Hebly Theunissen architecten, Delft; and Michael van Gessel landscapes, Amsterdam for the restoration of the Justus van Effen Complex. Located in Rotterdam, the Netherlands, the complex was designed by Michiel Brinkman in 1919-1921, and completed in 1922. The Justus van Effen complex is a remarkable example of early Modernism, and is emblematic of the ideals embodied in the Modern movement. The concept and execution of these 264 dwellings in Rotterdam’s new Spangen district were impressively novel in 1922. Combining typologies of the perimeter block and the row house, the complex presented by far the most radical response to the pressing post WWI housing shortage in the Netherlands. The boldly cantilevered walkway above the second floor reduced vertical circulation space and tied the complex together, while creating a careful balance between the collective and the private. The flat roofs, sparse and delicate ornamentation, careful contrast of bricks with exposed concrete, and open corner loggias tested key interventions that were damaging to the physical fabric. It elements and strategies of the emerging modern movement. also reflects the technological innovation that founded the original design by introducing state of the art energy-saving In the context of Spangen, a neighborhood that has faced devices for climate control. -
Modernism-Hizuchi.Pdf
2012 award to The Architectural Consortium for Hizuchi Elementary School SUZUKI Hiroyuki, MAGATA Kiyotada, HANADA Yoshiaki, WADA Kouichi, TAKECHI Kazutomi, KOSHIHARA Mikio, and Yawatahama City, OHSHIRO Ichiro, Mayor, for the restoration of Hizuchi Elementary School Yawatahama City, Ehime Prefecture, Japan Designed by MATSUMURA Masatsune 1956–1958 Jury Citation THE 2012 WORLD MONUMENTS FUND/KNOLL MODERNISM PRIZE is awarded to the Architectural Consortium for Hizuchi Elementary School for the restoration of Hizuchi Elementary School. Located in Yawatahama City, Ehime Prefecture, Japan, Hizuchi was designed by MATSUMURA Masatsune, constructed from 1956 to 1958, and restored by the Con- sortium from 2008 to 2009. In its review of the nominations, the jury was delighted to discover an exemplary building in the history of post-war modernist architecture in Japan little known, as yet, outside the country. Even at the time it was built, Hizuchi, a wood-framed modern structure located in a small, relatively re- mote Japanese town, took the Japanese architectural profession by surprise for its originality and conviction. Of local and national significance, Hizuchi Elementary School has been saved and masterfully restored, and has been re-inscribed in national modern architectural history. It can now be recognized internationally as both an extremely fine building and an absolutely impeccable res- toration project. Equally impressive was the process by which the community was engaged, came to re-appre- ciate, and eventually saved the school despite some initial sentiment to tear it down following ex- tensive damage in a 2004 typhoon. It is a living piece of the community once again—where school- children are interacting with a very finely designed building in everything from education and recreation to their part in daily maintenance. -
The Architectural Programming of the Royal Melbourne Hospital 1935–45? the Sub-Questions Are As Follows
DESIGN-BY-DIALOGUE: THE ARCHITECTURAL PROGRAMMING OF THE ROYAL MELBOURNE HOSPITAL 1935 – 1945 Catherine Ann Tate Submitted in total fulfilment of the requirements of the degree of Doctor of Philosophy March 2016 Faculty of Architecture, Building and Planning The University of Melbourne Printed on Archival Paper In memory of my mother and father, Winifred (Win) and John (Jack) Tate We shall not cease from exploration. And the end of all our exploring Will be to arrive where we started And know the place for the first time. TS Eliot (1943), Little Gidding V, Four Quartets. Catherine Tate ABSTRACT This dissertation argues that the dialogue between expert clients and expert architects is critical to the creation of a general hospital – arguably the most programmatically complex of all building types. Using the third realisation of the Royal Melbourne Hospital (RMH), the initial structure on the Parkville site, 1935-45, as an historical example, this dissertation provides significant insights into rarely recorded programming interaction between the clients, the RMH, and the architects, Stephenson Meldrum/Turner (SM/T). The RMH was (and still is) a premier health, teaching and research facility within Australia. In 1935, the RMH’s goal for the new hospital was to create a modern teaching hospital on a par with the world’s best. This clearly was achieved as, in 1945, the hospital buildings had gained significance within the Australian hospital architectural milieu for being the first general public hospital to be completed in the vertical typology and implementing the modernist principles of functionality and the minimalist aesthetic. It was also particularly significant within the hospital oeuvre of SM/T as it was their first general hospital and one which became the exemplar for their later hospital work. -
Life in the Open Air: the Persistence of Outdoor Air Treatment for Pulmonary
James Madison University JMU Scholarly Commons Masters Theses The Graduate School Spring 2011 Life in the open air: The persistence of outdoor air treatment for pulmonary tuberculosis patients in America from the Industrial Revolution to the 1950s Tara Darlene Mastrangelo James Madison University Follow this and additional works at: https://commons.lib.jmu.edu/master201019 Part of the History Commons Recommended Citation Mastrangelo, Tara Darlene, "Life in the open air: The persistence of outdoor air treatment for pulmonary tuberculosis patients in America from the Industrial Revolution to the 1950s" (2011). Masters Theses. 268. https://commons.lib.jmu.edu/master201019/268 This Thesis is brought to you for free and open access by the The Graduate School at JMU Scholarly Commons. It has been accepted for inclusion in Masters Theses by an authorized administrator of JMU Scholarly Commons. For more information, please contact [email protected]. Life in the Open Air: The Persistence of Outdoor Air Treatment for Pulmonary Tuberculosis Patients in America from the Industrial Revolution to the 1950s Tara Mastrangelo A thesis submitted to the Graduate Faculty of JAMES MADISON UNIVERSITY In Partial Fulfillment of the Requirements for the degree of Master of Arts History May 2011 Acknowledgements First and foremost, I would like to express appreciation for my thesis advisor, Dr. Raymond M. Hyser, for all of his guidance, enthusiasm, and support during the thesis writing process and in general. Despite having many advisees he was always willing to make time to meet, for which I am extremely grateful. He urged me on with patience and humor every step of the way. -
Tuberculosis Transcriptomics
Tuberculosis Transcriptomics: Host Protection and ImmuneTown Evasion Mechanisms Cape of Mumin OZTURK Thesis submitted to the University of Cape Town in fulfillment of the University degree Doctor of Philosophy Cytokines and Disease Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component and Institute of Infectious Diseases and Molecular Medicine (IDM), Division of Immunology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. The copyright of this thesis vests in the author. No quotation from it or information derived from it is to be published without full acknowledgement of the source. The thesis is to be used for private study or non- commercial research purposes only. Published by the University of Cape Town (UCT) in terms of the non-exclusive license granted to UCT by the author. University of Cape Town TABLE OF CONTENTS ACKNOWLEDGEMENTS……………………………………………………………………….4 ABSTRACT……………………………………………………………………………………….5 LIST OF PUBLICATIONS………………………………………………………………………..6 LIST OF ABBREVIATIONS……………………………………………………………………..7 CHAPTER I LITERATURE REVIEW…………………………………………………………...9 1.1 HISTORY of TUBERCULOSIS………………………………………………………9 1.2 TUBERCULOSIS: CURRENT SITUATION and INSIGHTS……………………...15 1.3 TUBERCULOSIS IMMUNOPATHOLOGY……………………………………….16 1.4 MTB AND MACROPHAGE INTERPLAY………………………………………...21 CHAPTER II TRANSCRIPTOMICS OF MTB INFECTED MACROPHAGES………………29 2.1 ROLE OF FUNCTIONAL GENOMICS TO UNDERSTAND IMMUNE RESPONSES ……………………………………………………………………………29 2.2 CAP ANALYSIS GENE EXPRESSION -
Conserving Modern Architecture Issue. Spring 2013 (PDF Edition)
29215 GCI_NewsSpr13 R1.indd 1 4/19/13 9:17 AM A Note from the Director For the past few decades, our colleagues who advocated for the preservation of great twentieth-century architecture have been suc- cessful. They have not only saved important buildings—think the De La Warr Pavilion in England or the Century Plaza Hotel in my hometown of Los Angeles—but have also, in the process, raised public consciousness of their significance and helped preserve the ideas of optimism, innovation, and prog- ress that they contain. These colleagues have my admiration and appreciation! Still, despite these successes and a considerable amount of work on issues facing practitioners, done early on by a number of key organizations, the conservation field has lagged behind in the research necessary for the develop- ment of best-practice solutions for the maintenance, repair, and renovation of these structures. Working closely with international partners, our Conserving Modern Architecture Initiative (CMAI) attempts to reinvigorate some of those efforts that began in the 1990s. We seek to bring a strategic focus to these challenges through a program of research, through the development and dissemination of knowledge intended to fill identified gaps in practice, and through training and education efforts. This edition of Conservation Perspectives is a small piece of this effort. The feature article in this edition is authored by Susan Macdonald, who not only is head of GCI Field Projects, but also serves as the project director of the CMAI. In her article she notes the relatively recent emergence of myriad organizations dedicated to saving and conserving modern heritage and delineates the challenges that lie ahead, including achieving widespread recognition and support for the conservation of twentieth-century places, as well as developing a common vision and approach to do so. -
Fuelling Drug Discovery Against Mycobacterium Tuberculosis
More Medicines for Tuberculosis: Fuelling Drug Discovery against Mycobacterium tuberculosis THÈSE NO 8906 (2018) PRÉSENTÉE LE 5 OCTOBRE 2018 À LA FACULTÉ DES SCIENCES DE LA VIE UNITÉ DU PROF. COLE PROGRAMME DOCTORAL EN BIOTECHNOLOGIE ET GÉNIE BIOLOGIQUE ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE POUR L'OBTENTION DU GRADE DE DOCTEUR ÈS SCIENCES PAR Shi-Yan Caroline FOO acceptée sur proposition du jury: Prof. M. Blokesch, présidente du jury Prof. S. Cole, directeur de thèse Prof. P. Sander, rapporteur Prof. M. Jackson, rapporteuse Prof. K.-H. Altmann, rapporteur Suisse 2018 Summary Tuberculosis (TB), whose etiological agent is Mycobacterium tuberculosis (M. tuberculosis), has plagued humanity since antiquity. Even with chemotherapy available today, TB is the leading cause of death due to an infectious disease. Modern day factors, such as the HIV epidemic and the emergence of drug-resistant TB strains, have redefined the complexities and challenges of tackling the TB pandemic. Current treatments for TB are lengthy, and poor adherence to such prolonged treatment further exacerbates the issue of drug resistance. Moreover, therapies for drug-resistant TB have low cure rates. There is therefore a pressing need for improved therapies that are short and efficacious against all TB strains, which can be achieved through new antimicrobials that are more potent and have novel mechanisms of action, in addition to being affordable, orally bioavailable, and without drug-drug interactions. Such new anti-TB drugs need to be discovered and developed through a long, risky, and costly process, in which attrition rates are high. While there are promising compounds currently being developed, including the benzothiazinones (BTZs), it is necessary to further populate and enhance the Global TB drug pipeline to ensure the availability of new drugs.