DOCSLIB.ORG

REVIEW Doi: 10.12032/TMRCR20200728016

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
REVIEW Doi: 10.12032/TMRCR20200728016 REVIEW doi: 10.12032/TMRCR20200728016 TMR Clinical Research Meta-analysis of the clinical efficacy and safety of Urinary Kallidinogenase in the treatment of acute cerebral infarction Yuan Qin1, Qian Yi2, Hui-Hui Shi2, Ya-Lin Qi2*, Jing-Yue Hu2 1Chongqing Mental Health Center, Geleshan ward eight ward, Chongqing 400036, China. 2Military Army Medical University (Third Military Medical University) Daping Hospital Neurology, Chongqing 400010, China. *Corresponding to: Ya-Lin Qi. Daping Hospital, Army Medical University (Third Military Medical University. NO. 10, Changjiang branch road, Daping, Yuzhong district, Chongqing 400042, China. E-mail: [email protected]. Highlights The treatment of cerebral infarction by Urinary Kallidinogenase can improve the neurological defect symptoms, improve the quality of life, and the adverse reaction rate is low, and the safety is good, which provides evidence-based evidence for the treatment of cerebral infarction by Urinary Kallidinogenase. Submit a manuscript: https://www.tmrjournals.com/tcr TMR | November 2020 | vol. 3 | no. 4 | 131 doi: 10.12032/TMRCR20200728016 REVIEW Abstract Objective: To evaluate the clinical efficacy and safety of Urinary Kallidinogenase for Injection in the treatment of acute cerebral infarction. Methods: PubMed, The Cochrane Library, Embase, CNKI, VIP, Wan Fang and bibliographic database of Chinese medicine were searched by computer to collect randomized controlled trials of Urinary Kallidinogenase 's treatment of acute cerebral infarction. The time limit was set up until September 2019. At the same time, the references and grey literature in the literature were manually screened. Two independent researchers were screened, evaluated and extracted according to inclusion and exclusion criteria. Meta-analysis was carried out by RevMan 5.3 software. Results: A total of 17 randomized controlled trials involving 2,066 patients, including 1,033 in the experimental group, and 1,033 in the control group. meta-analysis results showed that compared with the conventional treatment, Urinary Kallidinogenase had better effect in the treatment of acute cerebral infarction [OR = 3.26, 95%CI (2.56, 4.16), P < 0.00001]; the national institule of Health Stroke Scale of the Urinary Kallidinogenase group was significantly better than that of the control group. Urinary Kallidinogenase group activity of daily living scale was better than the control group [OR = 21.33, 95%CI (6.64, 36.01), P = 0.004]; a total of 7 articles reported adverse reactions, including 19 cases in the trial group and 21 cases in the control group, the main adverse reactions were blood pressure drop, other symptoms were chest tightness, facial redness, dizziness fever, nausea and vomiting, arrhythmia, and no other serious adverse reactions. It can recover itself. Conclusion: the available evidence shows that Urinary Kallidinogenase can effectively improve the symptoms of neurological deficits and improve the ability of daily living in patients with acute cerebral infarction, and is safe. However, the quality of the study is limited. Keywords: Human urinary kallikrein, Urinary Kallidinogenase, Acute cerebral infarction, Randomized controlled trial, meta-analysis Abbreviations: rt-PA, recombinant tissue plasminogen activator; RCT, randomized controlled trial; CT, computed tomography; MRI, magnetic resonance Imaging; NIHSS, national institutes of health stroke scale; ADL, activity of daily living; OR, odds ratio; CI, confidence interval; PNA, pentose nucleic acid; ACEI, angiotension converting enzyme inhibitors; hk1, hexokinase 1. Competing interests: The authors declare that there is no conflict of interest. Citation: Yuan Qin, Qian Yi, Hui-Hui Shi, et al. Meta-analysis of the clinical efficacy and safety of Urinary Kallidinogenase in the treatment of acute cerebral infarction. TMR Clinical Research 2020, 3(4): 131–141. Executive Editor: Shan-Shan Lin. Submitted: 12 December 2019, Accepted: 12 May 2020, Online: 28 July 2020 TMR | November 2020 | vol. 3 | no. 4 | 132 Submit a manuscript: https://www.tmrjournals.com/tcr REVIEW doi: 10.12032/TMRCR20200728016 magnetic resonance Imaging (MRI) patients with a Background cute cerebral infarction within 72 hours had no ge nder or age. No strict gravity center, liver or kidn At present, stroke has become the first cause of death ey insufficiency, no systemic bleeding or bleeding in China. It is also an important cause of disability. Its tendency. main clinical manifestations are disturbance of (3) The intervention group adopted the same routine consciousness, dysfunction and other symptoms. It has treatment, including lowering blood fat, anti-platelet a high disability rate and mortality rate [1]. Cerebral aggregation, nourishing brain cells and improving the infarction, also known as ischemic stroke, is caused by cerebral circulation. The experimental group was local cerebral vascular supply disorders leading to additionally given Urinary Kallidinogenase, while the hypoxic degeneration and necrosis of the brain tissue, control group was given placebo, inactive or active resulting in a corresponding clinical neurological drugs on the routine treatment. Two groups were given deficit 80%, which accounts for all stroke types, is the same treatment. used in the treatment of acute cerebral infarction. In (4) Outcome measures: effective rate: the National addition to recombinant tissue plasminogen activator Institutes of Health Stroke Scale (NIHSS) was used to (rt-PA), an antiplatelet drug aspirin and thrombolytic evaluate the improvement of neurological deficits at drugs, has become an international guideline for grade the end of treatment. The following criteria were A and grade I recommendation. The evidence for other adopted to improve the degree of improvement: the drugs is not yet sufficient. Therefore, it is of great basic cure was: the neurological deficit score was significance to study new drugs for improving cerebral reduced by 90%–100%, the disability degree was 0 circulation and protecting brain function. grade; significant progress was achieved: the Urinary Kallidinogenase, also known as the human neurological impairment score was reduced by 46%– Urinary Kallidinogenase (trade name, Kai Likang), is a 89%, and the disability degree was 1–3; progress: serine proteinase composed of 238 amino acids neurological deficit score decreased by 18%–45%; no extracted from the urine of healthy men. It is a new change: neurological impairment score decreased or class I drug developed in recent years in China. It has increased by 18%; deterioration: neurological been shown that the drug has a certain dose under impairment score increased 18%. Improved conversion certain dose. It can expand the small artery in ischemic to classification variable effective and invalid, which area, increase blood flow in ischemic brain tissue, and will be effectively defined as basic cure, significant improve cerebral circulation in 10 years. In October progress and progress, Total Efficiency = (Basic Cure 2005, it was approved by The State Food and Drug + Significant Progress + Progression/Total Number) × Administration and widely used in clinical practice.In 100%; NIHSS score; 3 activity of daily living scale recent years, the drug has been more widely used in (ADL) score. China, and the corresponding clinical randomized (5) Adverse reactions were defined as intracranial controlled trials (RCT) are also increasing, but the hemorrhage, extracranial blood, allergies, and research quality is uneven, so it is necessary to carry unexplained organ dysfunction. out systematic evaluation to provide evidence-based medical evidence for it. Exclusion criteria (1) Non randomized controlled trials. Materials and methods (2) There is no clear diagnosis, inclusion and exclusion criteria. Search strategy Computer (3) The course of treatment is inconsistent and there is Search strategy retrieves databases such as PubMe d, no definite criteria for evaluating the therapeutic effect. The Cochrane Library, Embase, CNKI, VIP, Wa n (4) Repeated published studies. Fang and Chinese biomedical literature database. Registry from inception to September 2019. “Stro Data extraction ke” and Chinese search terms such as “Urinary K Extraction were carried out separately by two allidinogenase”, “human urinary kinase” and “cereb researchers, and the data were screened and extracted. ral infarction” were retrieved by combining themati If there were differences, reference was made to third c words and free words. people's opinions. The relevant documents were retrieved into the literature management software Inclusion criteria NoteExpress to read the titles and abstracts, and the (1) Study type: RCT, whether or not use blindness. articles that did not meet the inclusion criteria were Language is restricted to Chinese and English. carefully read out and screened again. Finally, the data (2) The subjects met the diagnostic criteria of cere included the first author or information provider, date bral infarction diagnosed by the Fourth National C of publication, age, time of entry, sample size, onference on cerebrovascular diseases, and confirm intervention measures, course of treatment, and ed by cranial computed tomography (CT) and/or outcome criteria. Submit a manuscript: https://www.tmrjournals.com/tcr TMR | November 2020 | vol. 3 | no. 4 | 133 doi: 10.12032/TMRCR20200728016 REVIEW analysis variables to draw funnel plots for publication Quality evaluation bias detection. According to the bias risk assessment method recommended in
Load more

Recommended publications
  • Role of PARP1-Mediated Autophagy in EGFR-TKI Resistance in Non
    www.nature.com/scientificreports OPEN Role of PARP1‑mediated autophagy in EGFR‑TKI resistance in non‑small cell lung cancer Zhimin Zhang1,4, Xiaojuan Lian2,4, Wei Xie1, Jin Quan2, Maojun Liao1, Yan Wu3, Zhen‑Zhou Yang3,4* & Ge Wang1,4* Resistance to epidermal growth factor receptor‑tyrosine kinase inhibitors (EGFR‑TKIs) has become the main clinical challenge of advanced lung cancer. This research aimed to explore the role of PARP1‑ mediated autophagy in the progression of TKI therapy. PARP1‑mediated autophagy was evaluated in vitro by CCK‑8 assay, clonogenic assay, immunofuorescence, and western blot in the HCC‑827, H1975, and H1299 cells treated with icotinib (Ico), rapamycin, and AZD2281 (olaparib) alone or in combination. Our results and GEO dataset analysis confrmed that PARP1 is expressed at lower levels in TKI‑sensitive cells than in TKI‑resistant cells. Low PARP1 expression and high p62 expression were associated with good outcomes among patients with NSCLC after TKI therapy. AZD2281 and a lysosomal inhibitor reversed resistance to Ico by decreasing PARP1 and LC3 in cells, but an mTOR inhibitor did not decrease Ico resistance. The combination of AZD2281 and Ico exerted a markedly enhanced antitumor efect by reducing PARP1 expression and autophagy in vivo. Knockdown of PARP1 expression reversed the resistance to TKI by the mTOR/Akt/autophagy pathway in HCC‑827IR, H1975, and H1299 cells. PARP1‑mediated autophagy is a key pathway for TKI resistance in NSCLC cells that participates in the resistance to TKIs. Olaparib may serve as a
    [Show full text]
  • Download Thesis
    This electronic thesis or dissertation has been downloaded from the King’s Research Portal at https://kclpure.kcl.ac.uk/portal/ Across the Geo-political Landscape Chinese Women Intellectuals’ Political Networks in the Wartime Era 1937-1949 Guo, Xiangwei Awarding institution: King's College London The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without proper acknowledgement. END USER LICENCE AGREEMENT Unless another licence is stated on the immediately following page this work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence. https://creativecommons.org/licenses/by-nc-nd/4.0/ You are free to copy, distribute and transmit the work Under the following conditions: Attribution: You must attribute the work in the manner specified by the author (but not in any way that suggests that they endorse you or your use of the work). Non Commercial: You may not use this work for commercial purposes. No Derivative Works - You may not alter, transform, or build upon this work. Any of these conditions can be waived if you receive permission from the author. Your fair dealings and other rights are in no way affected by the above. Take down policy If you believe that this document breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. Download date: 30. Sep. 2021 Across the Geo-political Landscape: Chinese Women Intellectuals’ Political
    [Show full text]
  • Chongqing Handbook All Essential Information You Need to Know About Chongqing
    Chongqing Handbook All essential information you need to know about Chongqing Presented by Chongqing Expat Club www.cqexpat.com Copyright 2008. All Rights Reserved. Table of Contents CHAPTER ONE - ABOUT CHONGQING Page 3 CHAPTER TWO – THE CITY HUBS Page 3 CHAPTER THREE – CITY TRANSPORT Page 4 CHAPTER FOUR – ATTRACTIONS Page 6 CHAPTER FIVE – NIGHTLIFE & ENTERTAINMENT Page 16 CHAPTER SIX – ACCOMMODATION Page 18 CHAPTER SEVEN – INTERNATIONAL FOOD Page 21 CHAPTER EIGHT– SHOPPING Page 24 CHAPTER NINE - EDUCATION Page 27 CHAPTER TEN – HEALTH CARE Page 29 CHAPTER ELEVEN – EMBASSIES & CONSULATES Page 31 CHAPTER TWELVE – USEFUL CONTACTS Page 32 CHAPTER THIRTEEN – USEFUL WORDS and PHRASES Page 32 CHAPTER ONE - ABOUT CHONGQING Chongqing is the economic hub of southwest China and the fourth Municipality in China (after Beijing, Shanghai and Tianjin). Chongqing is situated in the east of southwest China, about 2,500km up the Yangtze River from Shanghai. Under its jurisdiction there are 40 districts, cities and counties. It covers an area of 82,000 square kilometres with a total population of 31 million. An estimated 6 million people live in urban Chongqing city. Downtown Chongqing lies at the point where the Yangtze River and the Jialing River merge. Known as the Mountain City, the whole city is built against a backdrop of hills and rivers, characterized by zig-zagging roads and overlapping houses. It is also known as one of the four Furnace Cities for its hot summers and the Foggy City for its misty winters. CHAPTER TWO – THE CITY HUBS Chongqing has five major business and shopping precincts - the oldest and most important being Jiefangbei situated within what remains of the Old Walled City.
    [Show full text]
  • FORMATO PDF Ranking Instituciones Acadã©Micas Por Sub áRea OCDE
    Ranking Instituciones Académicas por sub área OCDE 2020 1. Cs. Naturales > 1.06 Ciencias Biológicas PAÍS INSTITUCIÓN RANKING PUNTAJE USA Harvard University 1 5,000 USA Massachusetts Institute of Technology (MIT) 2 5,000 USA Stanford University 3 5,000 UNITED KINGDOM University of Oxford 4 5,000 UNITED KINGDOM University of Cambridge 5 5,000 USA University of California San Francisco 6 5,000 USA Johns Hopkins University 7 5,000 USA University of Washington Seattle 8 5,000 CANADA University of Toronto 9 5,000 UNITED KINGDOM University College London 10 5,000 USA University of California San Diego 11 5,000 USA University of Pennsylvania 12 5,000 USA Cornell University 13 5,000 DENMARK University of Copenhagen 14 5,000 USA University of Michigan 15 5,000 USA University of California Berkeley 16 5,000 USA University of California Los Angeles 17 5,000 UNITED KINGDOM Imperial College London 18 5,000 FRANCE Sorbonne Universite 19 5,000 USA Duke University 20 5,000 AUSTRALIA University of Queensland 21 5,000 AUSTRALIA University of Melbourne 22 5,000 USA University of California Davis 23 5,000 USA Columbia University 24 5,000 USA Yale University 25 5,000 USA University of North Carolina Chapel Hill 26 5,000 USA University of Minnesota Twin Cities 27 5,000 USA Washington University (WUSTL) 28 5,000 UNITED KINGDOM University of Edinburgh 29 5,000 SWEDEN Karolinska Institutet 30 5,000 NETHERLANDS Utrecht University 31 5,000 USA University of Florida 32 5,000 USA University of Wisconsin Madison 33 5,000 USA Baylor College of Medicine 34 5,000 USA
    [Show full text]
  • List of Medical Device Clinical Trial Filing Institutions
    List Of Medical Device Clinical Trial Filing Institutions Serial Record number Institution name number Beijing: 5 6 Ge Mechanical temporary 1 agency Beijing Tsinghua Chang Gung Memorial Hospital preparation 201800003 Mechanical temporary 2 agency Plastic Surgery Hospital of Chinese Academy of Medical Sciences preparation 201800008 Mechanical temporary 3 agency Beijing Youan Hospital, Capital Medical University preparation 201800019 Mechanical temporary 4 agency Peking University Shougang Hospital preparation 201800044 Mechanical temporary 5 agency Beijing Cancer Hospital preparation 201800048 Mechanical temporary 6 agency Eye Hospital of China Academy of Chinese Medical Sciences preparation 201800077 Mechanical temporary Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical 7 agency University preparation 201800086 Mechanical temporary 8 agency Beijing Anorectal Hospital (Beijing Erlong Road Hospital) preparation 201800103 Mechanical temporary 9 agency Cancer Hospital of Chinese Academy of Medical Sciences preparation 201800108 Serial Record number Institution name number Mechanical temporary Peking Union Medical College Hospital, Chinese Academy of Medical 10 agency Sciences preparation 201800119 Mechanical temporary 11 agency Beijing Luhe Hospital, Capital Medical University preparation 201800128 Mechanical temporary 12 agency Beijing Huilongguan Hospital preparation 201800183 Mechanical temporary 13 agency Beijing Children's Hospital, Capital Medical University preparation 201800192 Mechanical temporary 14 agency
    [Show full text]
  • Annual Report 2019
    HAITONG SECURITIES CO., LTD. 海通證券股份有限公司 Annual Report 2019 2019 年度報告 2019 年度報告 Annual Report CONTENTS Section I DEFINITIONS AND MATERIAL RISK WARNINGS 4 Section II COMPANY PROFILE AND KEY FINANCIAL INDICATORS 8 Section III SUMMARY OF THE COMPANY’S BUSINESS 25 Section IV REPORT OF THE BOARD OF DIRECTORS 33 Section V SIGNIFICANT EVENTS 85 Section VI CHANGES IN ORDINARY SHARES AND PARTICULARS ABOUT SHAREHOLDERS 123 Section VII PREFERENCE SHARES 134 Section VIII DIRECTORS, SUPERVISORS, SENIOR MANAGEMENT AND EMPLOYEES 135 Section IX CORPORATE GOVERNANCE 191 Section X CORPORATE BONDS 233 Section XI FINANCIAL REPORT 242 Section XII DOCUMENTS AVAILABLE FOR INSPECTION 243 Section XIII INFORMATION DISCLOSURES OF SECURITIES COMPANY 244 IMPORTANT NOTICE The Board, the Supervisory Committee, Directors, Supervisors and senior management of the Company warrant the truthfulness, accuracy and completeness of contents of this annual report (the “Report”) and that there is no false representation, misleading statement contained herein or material omission from this Report, for which they will assume joint and several liabilities. This Report was considered and approved at the seventh meeting of the seventh session of the Board. All the Directors of the Company attended the Board meeting. None of the Directors or Supervisors has made any objection to this Report. Deloitte Touche Tohmatsu (Deloitte Touche Tohmatsu and Deloitte Touche Tohmatsu Certified Public Accountants LLP (Special General Partnership)) have audited the annual financial reports of the Company prepared in accordance with PRC GAAP and IFRS respectively, and issued a standard and unqualified audit report of the Company. All financial data in this Report are denominated in RMB unless otherwise indicated.
    [Show full text]
  • A Spatial Statistical Analysis on Intra-Country Economy in Chongqing from Inputs Point of View
    ISSN 1913-0341 [Print] Management Science and Engineering ISSN 1913-035X [Online] Vol. 8, No. 4, 2014, pp. 1-7 www.cscanada.net DOI: 10.3968/6127 www.cscanada.org A Spatial Statistical Analysis on Intra-Country Economy in Chongqing From Inputs Point of View GAO Yuandong[a],*; ZHANG Na[b]; ZHAO Xiaoming[b] [a]Associate Professor, College of Economics and Management, Gao, Y. D., Zhang, N., & Zhao, X. M. (2014). A Spatial Statistical Southwest University, Chongqing, China. Analysis on Intra-Country Economy in Chongqing From Inputs Point [b]College of Economics and Management, Southwest University, of View. Management Science and Engineering, 8(4), 1-7. Available Chongqing, China. from: URL: http://www.cscanada.net/index.php/mse/article/view/6127 *Corresponding author. DOI: http://dx.doi.org/10.3968/6127 Supported by the Major Program of National Social Science Foundation of China (12&ZD100); the National Social Science Foundation of China (14BJY125); the Social Science Foundation of Ministry of Education of China (12YJC790041); the China Postdoctoral Science Foundation INTRODUCTION (2013M540687); the Key Program of Humanities and Social Science Since Chongqing became the municipality in 2007, its Key Research Bases in Chongqing (13SKB020); the Key Program of Higher Education Teaching Reform Research in Chongqing (132061). economic comprehensive strength has increased a lot. From 1997 to 2011, Chongqing’s nominal GDP has Received 18 September 2014; accepted 25 November 2014 increased from 150.975 billion to 1001.137 billion, the Published online 16 December 2014 economic aggregate has expanded by 6.63 times, its average annual growth rate has reached to 14.66%, which Abstract is 1.1% higher than the average annual growth rate of In order to analyze the region difference and the dynamic national nominal GDP ( the annual growth rate of national changes of intra-country economy in Chongqing since nominal GDP from 1997 to 2011 is 13.56%).
    [Show full text]
  • The Construction and Prospects of the Chongqing Twin Children Database
    The Construction and Prospects of the Chongqing Twin Children Database Yixiao Fu,1 Peng Xie,3 Huaqing Meng,1 Qing Qin,1 Lu Jia,1 Qi Li,3 Yi Huang,2 Xiao Hou,5 Qinghua Luo,1 Xiaohong Ma,2 Wei Deng,3 Yingcheng Wang,3 Hua Hu,1 Lian Du,1 Kun Feng,1 Haitang Qiu,1 Yun Xiang,4 and Tao Li6 1 Department of Psychiatry, The First Affiliated Hospital, Chongqing Medical University, Chongqing, China 2 Department of Psychiatry, West China Hospital, Sichuan University, Chengdu, China 3 Department of neurology The First Affiliated Hospital, Chongqing Medical University, Chongqing, China 4 The Forth Hospital of Chengdu, Chengdu, China 5 Chongqing Medicine College, Chongqing, China 6 King’s College London, Department of Psychological Medicine, Institute of Psychiatry, London, United Kingdom wins could play a crucial role in our understanding the proportion of children under the age of 16 in the Tof genetic contributions to numerous etiologically total population of developing countries is higher than complex disorders. In China, although adult twins are that of developed countries, the total number of relatively rare, twins will become increasingly avail- affected children is much higher. Currently, the inci- able due to increasing twin birth rates. Thus, child dence of child mental health problems is approximately twin data will be a valuable resource to contribute to 15% in China (Junmian, 2000; Xueyong, 2002), the field of child and adolescent psychopathology. meaning that 50 million children and teenagers may The first twin database of children aged from 6 to 16 need mental health services. was established in Chongqing, R.P., China.
    [Show full text]
  • The People's Liberation Army's 37 Academic Institutions the People's
    The People’s Liberation Army’s 37 Academic Institutions Kenneth Allen • Mingzhi Chen Printed in the United States of America by the China Aerospace Studies Institute ISBN: 9798635621417 To request additional copies, please direct inquiries to Director, China Aerospace Studies Institute, Air University, 55 Lemay Plaza, Montgomery, AL 36112 Design by Heisey-Grove Design All photos licensed under the Creative Commons Attribution-Share Alike 4.0 International license, or under the Fair Use Doctrine under Section 107 of the Copyright Act for nonprofit educational and noncommercial use. All other graphics created by or for China Aerospace Studies Institute E-mail: [email protected] Web: http://www.airuniversity.af.mil/CASI Twitter: https://twitter.com/CASI_Research | @CASI_Research Facebook: https://www.facebook.com/CASI.Research.Org LinkedIn: https://www.linkedin.com/company/11049011 Disclaimer The views expressed in this academic research paper are those of the authors and do not necessarily reflect the official policy or position of the U.S. Government or the Department of Defense. In accordance with Air Force Instruction 51-303, Intellectual Property, Patents, Patent Related Matters, Trademarks and Copyrights; this work is the property of the U.S. Government. Limited Print and Electronic Distribution Rights Reproduction and printing is subject to the Copyright Act of 1976 and applicable treaties of the United States. This document and trademark(s) contained herein are protected by law. This publication is provided for noncommercial use only. Unauthorized posting of this publication online is prohibited. Permission is given to duplicate this document for personal, academic, or governmental use only, as long as it is unaltered and complete however, it is requested that reproductions credit the author and China Aerospace Studies Institute (CASI).
    [Show full text]
  • Residential Savills Research
    Chongqing – January 2021 MARKET IN MINUTES Residential Savills Research Savills team Please contact us for further information RESEARCH James Macdonald Senior Director China +8621 6391 6688 james.macdonald@ Prices in main urban areas rise savills.com.cn Sophy Pan The average transaction price in the main urban areas increased to RMB13,300 Senior Manager sq m. Western China +8628 6737 3737 • The supply of first-hand commodity housing in the main • In 2H/2020, Chongqing’s Housing, Urban and Rural sophy.pan@ savills.com.cn urban area1of Chongqing increased 11.1% to 6.7 million sq m Construction Commission announced that enterprises can quarter-on-quarter (QoQ) in Q4/2020. apply for an employee housing accumulation fund reduction, down to the minimum of 5%, in order to alleviate the cash CENTRAL MANAGMENT • The transaction volume of first-hand commodity housing in pressure on companies due to the fallout of COVID-19. Eric Wo the main urban area increased 22.9% to 6.5 million sq m in Managing Director Q4/2020. Western China +8628 8658 7828 • The transaction price of first-hand housing in the main [email protected] urban area rose slightly to RMB13,300. Savills plc Savills is a leading global real • The transaction volume of residential land increased estate service provider listed on 76.2% QoQ to 4 million sq m, and the average floor price of “Relatively stable market the London Stock Exchange. The company established in 1855, has residential land fell 19.2% QoQ to RMB5,109 per sq m. a rich heritage with unrivalled demand at the end of growth.
    [Show full text]
  • Food Production in Chongqing, China: Opportunities and Challenges
    Middle States Geographer, 2016, 49: 55-62 FOOD PRODUCTION IN CHONGQING, CHINA: OPPORTUNITIES AND CHALLENGES M. Rock*, S. Engel-Di Mauro*, S. Chen, M. Iachetta, A. Mabey, K. McGill, J. Zhao Department of Geography, State University of New York at New Paltz 1 Hawk Drive, New Paltz, NY 12561 ABSTRACT: Urban food production (UFP) has been the subject of much interest, especially in light of worldwide urbanization trends. There have been many place-specific studies and overviews about UFP, but very little in China. Studies investigating enabling and constraining conditions and people’s motivations for UFP have also largely omitted China and they have entirely missed one of the fastest growing cities in the world, Chongqing. Research was carried out in several districts of Chongqing to assess the social composition of urban farmers and the conditions they face, as well as find out their reasons for farming in the city. Methods included transect walks, semi-structured interviews, crop inventory, and soil field analysis. Thirty interviews were carried out involving 37 participants, and crop and soil descriptions were completed at 28 and 15 sites, respectively. Results indicate that a majority of urban food producers are women and people older than 30 years. Most are not city natives and little more than half have had prior farming experience. They grow food often on thin soils in marginal spaces, usually having precarious land access contingent on business or government decisions that can lead to eviction or field destruction. Nevertheless, farmers grow a diversity of crops and sometimes raise other animals. Most farming is for subsistence and/or recreational and social networking possibilities afforded by UFP.
    [Show full text]
  • For More Details Or Information, Please Contact Director of Sales And
    Monument of Liberation Hotel Exterior INTERCONTINENTAL CHONGQING Address 101, Minzu Road, Yuzhong District, Chongqing, 400010, People’s Republic of China Telephone (86-23) 8906 6888 Facsimile (86-23) 8906 6999 Management InterContinental Hotels Group Holidex Code CHGHA Website www.intercontinental.com General Manager Ms.Sharon Fraser Toll Free Reservation No. 400 8840 888 Email: [email protected] For more details or information, please contact Director of Sales and Marketing-Rowena Zhang Sales Office 12th Floor, 101, Minzu Road, Yuzhong District, Chongqing, 400010, P.R China Contact No (86-23) 8906 6888 Ext: 6618 Fax No (86-23) 8906 6656 Email [email protected] THE HOTEL The InterContinental Chongqing, offering the finest five-star accommodation, facilities and services in the centre of Chongqing to cater to the most discerning travelers whether on business or for leisure. Including spacious rooms and suites, executive floors with private lounge, efficient business centre, large selection of bars and restaurants plus a comprehensive range of other leisure facilities such as swimming pool, spa, massage, gymnasium etc. Elegant banqueting, conference and meeting facilities and most importantly warm, friendly, attentive and caring service. InterContinental Chongqing’s entry into this city brings a new era to the Chongqing hotel landscape as the hotel offers spectacular city views and a landmark building in the cosmopolitan skyline nestled between the famed Jialing and Yangtze Rivers. As the city’s premier hotel, the InterContinental Chongqing exemplifies the excellent service and attention to detail for which the InterContinental name is globally renowned. LOCATION InterContinental Chongqing is centrally located in the heart of Chongqing’s Central Yuzhong District, the city’s business, shopping, sightseeing and entertainment district.
    [Show full text]