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Urology / Gynecology Business Unit (UGBU) Strategy
Urology / Gynecology Business Unit (UGBU) Strategy Minoru Okabe Head of Uro/Gyn Business Unit Olympus Corporation March 30, 2016 Todayʼs Agenda 1.Business Overview 2.Recognition of Current Conditions 3.Market Trends 4.Business Strategies 5.Targets and Indicators 2 2016/3/30 No data copy / No data transfer permitted Todayʼs Agenda 1.Business Overview 2.Recognition of Current Conditions 3.Market Trends 4.Business Strategies 5.Targets and Indicators 3 2016/3/30 No data copy / No data transfer permitted Positioning of UG Business within Olympus 4 2016/3/30 No data copy / No data transfer permitted Distribution of Sales and Positioning FY2016 Net Sales (Forecast) Urology / Gynecology Business Unit (UGBU)* ET 72.0 Surgical Flexible and rigid endoscopes Benign prostatic hypertrophy and bladder Medical Business Devices* GI (ureteroscopes and cystoscopes) tumor resectoscopes and therapeutic FY2016 Net Sales electrodes (disposable) 337.4 205.6 (Forecast) ¥615.0 billion Urology field Flexible hysteroscopes * The figure for Surgical Devices net sales (¥205.6 billion) includes Stone treatment Gynecology field net sales of the Urology / Gynecology Business Unit (UGBU). devices (disposable) Resectoscopes Colposcopes 5 2016/3/30 No data copy / No data transfer permitted Applications and Characteristics of Major Products Field Urology Flexible Ureteroscope Stone Treatment Therapeutic Flexible Cystoscope Resectoscope URF-V2 Devices Electrodes (Disposable) CYF-VH OES Pro. (Disposable) Product Flexible ureteroscopes are used for Flexible cystoscopes are Resectoscopes are used to treat treating urinary stones. used to treat bladder benign prostatic hypertrophy and Feature Olympus flexible ureteroscopes have a tumors. bladder tumors. dominating edge realized by merging GI Olympus flexible Bipolar TURis electrodes endoscope technologies with the small cystoscopes have a (disposable) boast higher levels of diameter scope technologies of former dominating edge realized cutting safety and performance company Gyrus. -
Male Infertility Low Testosterone
Male Infertility low testosterone. One of the first academic medical centers in the Both are fellowship-trained, male reproductive urologists prepared to deal nation to create a sperm bank continues to lead with the most complex infertility cases and the way in male infertility research and in complex to perform complex microsurgeries, such as vasectomy reversals and testicular-sperm clinical care. extraction. Partnering with URMC’s female infertility experts, the male infertility clinic An andrology lab and sperm bank were bank, today URMC’s Urology department is part of a designated in-vitro fertilization created more than 30 years ago at the now boasts two fellowship-trained male center of excellence in New York state. University of Rochester Medical Center infertility specialists—Jeanne H. O’Brien, (URMC). Grace M. Centola, Ph.D., M.D. and J. Scott Gabrielsen, M.D., Ph.D. Complex Care H.C.L.D., former associate professor of A nationally recognized male-infertility URMC’s male infertility clinicians see a Obstetrics and Gynecology at URMC, expert, O’Brien has received numerous growing number of patients with male- was instrumental in creating the bank, in awards and recognitions for both her factor infertility, such as decreased collaboration with Robert Davis, M.D., clinical and basic science research work. sperm counts, motility or morphology. and Abraham Cockett, M.D., from the Gabrielsen focuses on male reproductive The first steps in the care process are a Department of Urology. health, including male infertility, erectile baseline semen analysis, coupled with Building on the groundbreaking sperm dysfunction, male sexual dysfunction and an understanding of a patient’s health 4 UR Medicine | Department of Urology | urology.urmc.edu history. -
Post-Orgasmic Illness Syndrome: a Closer Look
Indonesian Andrology and Biomedical Journal Vol. 1 No. 2 December 2020 Post-orgasmic Illness Syndrome: A Closer Look William1,2, Cennikon Pakpahan2,3, Raditya Ibrahim2 1 Department of Medical Biology, Faculty of Medicine and Health Sciences, Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia 2 Andrology Specialist Program, Department of Medical Biology, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo Hospital, Surabaya, Indonesia 3 Ferina Hospital – Center for Reproductive Medicine, Surabaya, Indonesia Received date: Sep 19, 2020; Revised date: Oct 6, 2020; Accepted date: Oct 7, 2020 ABSTRACT Background: Post-orgasmic illness syndrome (POIS) is a rare condition in which someone experiences flu- like symptoms, such as feverish, myalgia, fatigue, irritabilty and/or allergic manifestation after having an orgasm. POIS can occur either after intercourse or masturbation, starting seconds to hours after having an orgasm, and can be lasted to 2 - 7 days. The prevalence and incidence of POIS itself are not certainly known. Reviews: Waldinger and colleagues were the first to report cases of POIS and later in establishing the diagnosis, they proposed 5 preliminary diagnostic criteria, also known as Waldinger's Preliminary Diagnostic Criteria (WPDC). Symptoms can vary from somatic to psychological complaints. The mechanism underlying this disease are not clear. Immune modulated mechanism is one of the hypothesis that is widely believed to be the cause of this syndrome apart from opioid withdrawal and disordered cytokine or neuroendocrine responses. POIS treatment is also not standardized. Treatments includeintra lymphatic hyposensitization of autologous semen, non-steroid anti-inflamation drugs (NSAIDs), steroids such as Prednisone, antihistamines, benzodiazepines, hormones (hCG and Testosterone), alpha-blockers, and other adjuvant medications. -
Pediatric Urology in the 21St Century
Pediatric Urology in the 21st Century • Richard Caesar, MD • Urologic Surgeons of Maine General Pediatric Urology • Undescended Testis • Acute pediatric scrotum • Urinary Tract Infection • Vesico-ureteral reflux • Lower urinary tract dysfunction • Circumcision • Hypospadias/labial adhesions • Varicocele Terminology Undescended; abdominal, canal, and pre-scrotal (superficial inguinal ring) Retractile Testis; palpable in canal; during examination, testis stays in scrotum; observation ; normal histology Terminology Ascending Testis; can be manipulated in to scrotum but does not stay; abnormal histology Ectopic testis; testis distal to the external ring but not in the scrotum; femoral, perineal or contralateral scrotum Infertility/UDT • Paternity • Bilateral 65% • Unilateral 89% • Control 93% Lee et al; PSU UDT Incidence depends on birth weight and prematurity NB 3 months Premature 30 % 10% Term 3 % 1% Rarely does descent occur past 3 months Cancer Risk in UDT • % DX Testis Ca • USA- AA 0.3% • Scandinavian 0.7% • UDT 3-5% • Contralateral of UDT 1.5-2% • Hussmann et al Pedi Urol 2001 12 months - delay in germ cell development (Ad spermatogonia) 24 month; peri-tubular fibrosis 3-4 yrs/Adulthood; Germ cell aplasia with vacuolization AUA Guidelines Guidelines Guidelines Differential for Scrotal Pain • Testicular Torsion 16-31% • Torsion of Appendix Testis 31-46% • Epididymitis • Hernia • Hydrocele • Tumor • Trauma • Henoch-Schonlein Purpura • Idiopathic Scrotal Edema • Varicocele History Timing of Onset of Pain • Torsion; acute/unrelenting • App -
Sexually Transmitted Infections Treatment Guidelines, 2021
Morbidity and Mortality Weekly Report Recommendations and Reports / Vol. 70 / No. 4 July 23, 2021 Sexually Transmitted Infections Treatment Guidelines, 2021 U.S. Department of Health and Human Services Centers for Disease Control and Prevention Recommendations and Reports CONTENTS Introduction ............................................................................................................1 Methods ....................................................................................................................1 Clinical Prevention Guidance ............................................................................2 STI Detection Among Special Populations ............................................... 11 HIV Infection ......................................................................................................... 24 Diseases Characterized by Genital, Anal, or Perianal Ulcers ............... 27 Syphilis ................................................................................................................... 39 Management of Persons Who Have a History of Penicillin Allergy .. 56 Diseases Characterized by Urethritis and Cervicitis ............................... 60 Chlamydial Infections ....................................................................................... 65 Gonococcal Infections ...................................................................................... 71 Mycoplasma genitalium .................................................................................... 80 Diseases Characterized -
Male Anorgasmia: from “No” to “Go!”
Male Anorgasmia: From “No” to “Go!” Alexander W. Pastuszak, MD, PhD Assistant Professor Center for Reproductive Medicine Division of Male Reproductive Medicine and Surgery Scott Department of Urology Baylor College of Medicine Disclosures • Endo – speaker, consultant, advisor • Boston Scientific / AMS – consultant • Woven Health – founder, CMO Objectives • Understand what delayed ejaculation (DE) and anorgasmia are • Review the anatomy and physiology relevant to these conditions • Review what is known about the causes of DE and anorgasmia • Discuss management of DE and anorgasmia Definitions Delayed Ejaculation (DE) / Anorgasmia • The persistent or recurrent delay, difficulty, or absence of orgasm after sufficient sexual stimulation that causes personal distress Intravaginal Ejaculatory Latency Time (IELT) • Normal (median) à 5.4 minutes (0.55-44.1 minutes) • DE à mean IELT + 2 SD = 25 minutes • Incidence à 2-11% • Depends in part on definition used J Sex Med. 2005; 2: 492. Int J Impot Res. 2012; 24: 131. Ejaculation • Separate event from erection! • Thus, can occur in the ABSENCE of erection! Periurethral muscle Sensory input - glans (S2-4) contraction Emission Vas deferens contraction Sympathetic input (T12-L1) SV, prostate contraction Bladder neck contraction Expulsion Bulbocavernosus / Somatic input (S1-3) spongiosus contraction Projectile ejaculation J Sex Med. 2011; 8 (Suppl 4): 310. Neurochemistry Sexual Response Areas of the Brain • Pons • Nucleus paragigantocellularis Neurochemicals • Norepinephrine, serotonin: • Inhibit libido, -
Pediatric & Adolescent Gynecology – a How to Approach (Didactic)
Pediatric & Adolescent Gynecology – A How To Approach (Didactic) PROGRAM CHAIR Joseph S. Sanfi lippo, MD Heather Appelbaum, MD Robert K. Zurawin, MD Sponsored by AAGL Advancing Minimally Invasive Gynecology Worldwide Professional Education Information Target Audience Educational activities are developed to meet the needs of surgical gynecologists in practice and in training, as well as, other allied healthcare professionals in the field of gynecology. Accreditation AAGL is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AAGL designates this live activity for a maximum of 3.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS As a provider accredited by the Accreditation Council for Continuing Medical Education, AAGL must ensure balance, independence, and objectivity in all CME activities to promote improvements in health care and not proprietary interests of a commercial interest. The provider controls all decisions related to identification of CME needs, determination of educational objectives, selection and presentation of content, selection of all persons and organizations that will be in a position to control the content, selection of educational methods, and evaluation of the activity. Course chairs, planning committee members, presenters, authors, moderators, panel members, and others in a position to control the content of this activity are required to disclose relevant financial relationships with commercial interests related to the subject matter of this educational activity. Learners are able to assess the potential for commercial bias in information when complete disclosure, resolution of conflicts of interest, and acknowledgment of commercial support are provided prior to the activity. -
EAU Guidelines on Ejaculatory Dysfunction G
European Urology European Urology 46 (2004) 555–558 Review EAU Guidelines on Ejaculatory Dysfunction G. Colpia, W. Weidnerb, A. Jungwirthc, J. Pomerold, G. Pappe, T. Hargreavef, G. Dohleg,* (EAU Working Party on Male Infertility) aAndrology Department, Osp. San Paolo, Milan, Italy bDepartment of Urology, Justus-Liebig-University, Giessen, Germany cDepartment of Urology and Andrology, Landeskliniken Salzburg, Salzburg, Austria dDepartment of Urology, Fundacio´ Puigvert, Barcelona, Spain eDepartment of Androloy/Urology, Semmelweis University Medical School, Budapest, Hungary fDepartment of Oncology, Western General Hospital, Edinburgh, United Kingdom gDepartment of Urology, Erasmus University Medical Centre Rotterdam, Dr. Molenwaterplein 40, 3015 GD Rotterdam, The Netherlands Accepted 23 July 2004 Available online 11 August 2004 Keywords: Ejaculation; Disorders; Diagnosis; Treatment; EAU guidelines 1. Int r o d uc tion sporadic events of nocturnal emission or of ejaculation occurring during great emotional excitement unrelated Disorders of ejaculation are uncommon but impor- to sexual activity [3]. tant causes of male infertility. Several heterogeneous dysfunctions belong to this group, and may be of either 2.3. Delayed ejaculation organic or functional origin. Delayed ejaculation is the condition wherein an abnormal stimulation of the erected penis is necessary to obtain an orgasm with ejaculation. It may be con- 2. Classification and aetiology sidered a slight form of anorgasmia: both can be alternatively found in the same patient. The causes 2.1. Anejaculation of delayed ejaculation may be psychological or Anejaculation is the complete absence of an ante- organic, e.g. incomplete spinal cord lesion [3], grade or retrograde ejaculation. It is caused by a failure iatrogenic penile nerve damage [4] pharmacological of emission of semen from the seminal vesicles, the (antidepressants, antihypertensives, antipsychotics). -
Acute Scrotum Medical Student Curriculum
ADVERTISEMENT 0 AUAU My AUA Join Journal of Urology Guidelines Annual Meeting 2017 ABOUT US EDUCATION RESEARCH ADVOCACY INTERNATIONAL PRACTICE RESOURCES Are you a Patient? EDUCATION > Educational Programs > Education for Medical Students > Medical Student Curriculum > Acute Scrotum Medical Student Curriculum ACUTE SCROTUM This document was amended in July 2016 to reflect literature that was released since the original publication of this content in May 2012. This document will continue to be periodically updated to reflect the growing body of literature related to this topic. KEY WORDS: Testis, epididymis, torsion, epididymitis, ischemia, tumor, infection, hernia Learning Objectives ADVERTISEMENT At the end of medical school, the student should be able to: ADVERTISEMENT 1. Describe 6 conditions that may produce acute scrotal pain or swelling. 2. Distinguish, through the history, physical examination and laboratory testing, testicular torsion, torsion of testicular appendices, epididymitis, testicular tumor, scrotal trauma and hernia. 3. Appropriately order imaging studies to make the diagnosis of the acute scrotum. 4. Determine which acute scrotal conditions require emergent surgery and which may be handled less emergently or electively. Introduction The "acute scrotum" may be viewed as the urologist's equivalent to the general surgeon's "acute abdomen." Both conditions are guided by similar management principles: The patient history and physical examination are key to the diagnosis and often guide decision making regarding whether or not surgical intervention is appropriate. Imaging studies should complement, but not replace, sound clinical judgment. When making a decision for conservative, non-surgical care, the provider must balance the potential morbidity of surgical exploration against the potential cost of missing a surgical diagnosis. -
Growth and Development of Male External Genitalia a Cross-Sectional Study of 6200 Males Aged 0 to 19 Years
ARTICLE Growth and Development of Male External Genitalia A Cross-sectional Study of 6200 Males Aged 0 to 19 Years Analia Tomova, MD, PhD; Fnu Deepinder, MD; Ralitsa Robeva, MD; Hristina Lalabonova, MD, PhD; Philip Kumanov, MD, PhD; Ashok Agarwal, PhD, HCLD Objective: To provide estimates of normal variations and penile circumference (measuring tape) from birth in penile measurements and testicular volumes, and to to 19 years of age. establish reference ranges for clinical use. Results: Testes did not show any increase in size until the onset of puberty at age 11 years, whereas penile growth Design: Cross-sectional, population-based study. was gradual after birth. However, both penile and testicu- lar development demonstrated peak growth from 12 to 16 Setting: Schools, kindergartens, and child care centers in different parts of Bulgaria. years of age, which coincided with the maximal male pu- bertal growth spurt. Data indicate an earlier pubertal de- Participants: A population of 6200 clinically healthy velopment for this study population than that for a simi- white males aged 0 to 19 years. lar population several decades ago. Significant differences betweenurbanandruralpopulationsregardingpenilelength Interventions: The study physician chose schools, were also noticed. kindergartens, and child care centers randomly and Conclusions: Our study provides the contemporary ref- examined children at random until he reached the erence range values for height, weight, testicular volume, required number. Each of the 20 age groups (age and penile length and circumference of males aged 0 to range, 0-19 years) had an equal number of males (ie, 19 years. Our data show that, even by the end of 20th cen- 310). -
Varicoceles What You Should Know
PEDIATRIC HEALTH Varicoceles What You Should Know What is Varicoceles? Men tend to find varicoceles during a self-exam. Doctors can diagnose it during a routine exam. Your urologist may order A varicocele is when the group of veins inside your scrotum a scrotal ultrasound test to see inside the scrotum. (the sac that holds your testicles) get bigger because of poor blood flow. These veins are called the pampiniform The Causes of Varicocele plexus. When they grow larger, they may look like a “bag of worms”. Varicoceles are more common on the left side. Ten Varicocele could happen for a few reasons. The valves in to fifteen men out of one hundred have this. It is like getting the veins may not work well (or may be missing). Blood may a varicose vein in your leg. pool in the veins if blood flow is sluggish. If blood pressure is weak, blood can flow backwards and cause the veins to Most of the time, varicoceles cause no problems and are swell. In rare cases, swollen lymph nodes or other masses harmless. They may cause pain, problems with fertility, or behind the belly can block blood flow and make the scrotal slow testicle growth in young boys. veins swell. What Happens Normally? Treatments for Varicocele The scrotum holds the testicles (testes) of the male Most of the time varicoceles are not treated. However, reproductive system. Sperm and the hormone testosterone treatment is offered for men who have fertility problems or are made in the testicles. abnormal semen, or if a boy’s testicle grows slowly. -
Clinical Observer in Male Fertility
Clinical Observer in Male Fertility Short-term training in male infertility is available at Cleveland Clinic’s Glickman Urological & Kidney Institute for candidates who have completed their urology residency. Foreign graduates are welcome to apply. An observer will have the opportunity to observe the clinical evaluation and surgical treatment of the infertile male. Additional didactic opportunities include participation in various research conferences, journal clubs and observing ongoing research in the American Center for Reproductive Medicine. Training Objectives: Candidates will observe clinical and surgical cases in male infertility with Sarah Vij, MD and Edmund Sabanegh, Jr., MD and interact with other members of faculty interested in men's health. Clinical Observer How to apply: An observer will: Those interested in this observership › Learn about emerging surgeries for the correction of anatomic should write to Nikki Williams at: causes of male factor infertility (example: microsurgical reconstructions such as vasovasostomy and Nikki Williams vasoepididymostomy) Project Manager › Understand the role of new assisted reproductive techniques Department of Urology in the management of infertility Glickman Urological and Kidney Institute Cleveland Clinic › Compare various techniques for harvest of sperm in non-obstructive azoospermia (example: microsurgical 9500 Euclid Ave/Q10 testicular sperm harvest, percutaneous epididymal Cleveland, OH 44195 USA sperm aspiration) Phone: 216.444.6320 Fax: 216.636.4492 Appointment: Observer in Urology Duration: 4 weeks E-mail: [email protected] Cleveland Clinic Urology Cleveland Clinic’s urology program is recognized worldwide for excellence in patient care, teaching, research and innovation. The program was ranked No. 1 by U.S. News & World Report in 2018-2019. Since 2000, Cleveland Clinic urology has been ranked No.