T&F Not for Distribution

Total Page:16

File Type:pdf, Size:1020Kb

T&F Not for Distribution Contents List of illustrations vii 6 Legal systems and the role of List of contributors xiii law in environmental health and Foreword One xvi approaches to regulation 167 Foreword Two xviii Catherine Davey and Stephen Battersby Preface xx T&F7 Business management, environmental health and the EHP/ 1 Historical context, philosophy and business interface 252 principles of environmental health 1 Not for distributionRoger Pearce Stephen Battersby 8 Environmental management systems 281 2 Environmental health – a changing John Barwise and Stephen Battersby practice 60 Chris Day 9 Constructions and related matters relevant to environmental health 310 3 Communication in environmental John Bryson and Stephen Battersby health 90 Sarah Daniels 10 Human physiology, hazards and health risks 343 4 Research and evidence-based David J. Baker; Naima Bradley, environmental health 102 Alec Dobney and Virginia Murray; Rob Couch, Caroline Barratt, Surindar Jill R. Meara and John O’Hagan; Dhesi, Jill Stewart and Alan Page Neil P. McColl; Caryn L. Cox 5 Regulation and environmental 11 Housing, health and the domestic health governance 128 environment 436 Rosalind Malcolm David Ormandy and Véronique Ezratty v Contents 12 Water and environmental health 454 19 Noise and vibration 879 Kathy Pond and Stephen Pedley Andrew Colthurst and Steve Fisher 13 Food, food safety and healthy eating 495 20 Port health 936 John Questier and Jenny Morris Iain Pocknell, Angela Tanner and John Ambrose 14 The work and leisure environments 619 Jonathan Hayes and Stuart Wiggans 21 Environmental health in different settings 976 15 Air and air quality 697 Virginia Murray, Gareth Moore, Geoff Stephen Hedley Ward and Andrew Charnick 16 Pest management and vector control 754 22 The international dimension 1002 Gai Murphy and David Oldbury Barrie Whitehead and Peter Wright 17 Waste management 790 Index 1021 Jeff Cooper 18 Land and land use 835 Alan Higgins T&F Not for distribution vi 1 Historical context, philosophy and principles of environmental health Stephen Battersby SECTION 1 A HISTORICAL PERSPECTIVE Introduction Poor Law Commission (and later Board) and Par- ishes were introduced. The municipal corporations As has been made clear in earlier editions of Clay’s, of the 1830s and the new Boards of Health were the history and development of what we now largely conceived to deal with outbreaks of com- call environmental health is long and complex.T&F As municable disease and to afford basic measures of Western societies developed (what would now be classified as the high-income countries1) so the health protection. Subsequently, a new concept of stressors on humanNot health increased; for indeed distributionper- health arose: the idea of public health. New phi- haps we can ignore the notion of ‘Western’ as there losophies for the delivery of education and other would have been both environmental and health public services began to take shape, and a new form impacts from the moment fire was discovered and of democracy evolved – extended suffrage, which wherever human groupings existed. The history became universal in the early twentieth century. and development of what we now call ‘environ- Environmental health as we know it has often mental health’, however, are closely allied to the been related to public health issues, and some- social history of the UK. times the impacts of different stressors. There are In the UK there were great economic, social and of course practitioners in the UK who qualified environmental changes in the eighteenth and nine- as Public Health Inspectors and remain proud of teenth centuries, when urbanisation and indus- that. Given that the real concern is with the impact trialisation brought millions of people together of environmental stressors on human health it is in crowded, sprawling and insanitary settlements. understandable why many prefer the term pub- In response, society underwent a period of rapid lic health particularly when the focus is on those change particularly motivated when the effects of stressors that are a consequence of human activity. the insanitary conditions spread to the middle and It remains true that environmental health practi- upper classes and the causes of cholera and typhoid tioners are part of the public health workforce. were identified. Impacts are not always the same as issues; whether New models for the delivery of public ser- an impact becomes an issue can depend on the vices to protect public health and maintain both public response, which is often linked to how the a healthier workforce and reduce the strain on the media report an impact. So a public health issue 1 Stephen Battersby reflects public or political pressure. An easy way to Earlier editions of this book sought to divide the think of the development of environmental health evolution of environmental health into eras. This is in the context of different developments in the historical perspective does not intend to replicate legal framework, but that is also to think in very that approach, rather to provide some pointers and narrow terms of environmental health. This section key issues in this evolution that have helped to of this first chapter looks at some environmental or define environmental health. public health issues over time and how they influ- The 20th edition had limited historical refer- enced the legal landscape at that time. However, ences, as it sought to look forward with broader environmental health is more than just a subject horizons, but since then a number of works (listed that relies on legislation and the implementation of in further reading) have perhaps underscored a those laws for its existence. Environmental health point made in the 19th edition that a historical could exist without any legislation, which provides perspective can make it easier to understand the only one means of addressing problems. current position. There is admittedly always the This section of the chapter looks at how envi- possibility that mistakes and tragedies of the past ronmental health as it is generally perceived has will be repeated, and not necessarily as farce (to developed in the British Isles. However, if one con- paraphrase Marx). This is true in the UK if as is siders the range of practitioners around the world possible public expenditure as a proportion of gross who consider themselves to be environmental domestic product (GDP) is reduced to 1930s levels. health practitioners, then we can see that even now Much of this historical perspective is linked to eco- there are slightly different interpretations or indeed nomic and social development. specialities within the overall concept. Historically many of the concerns were with The agricultural revolution the effects of waste on health and, as Mellanby [1] has said, quoting archaeologist Jacquetta Hawkes,T&F The agricultural revolution is taken as being the ‘waste disposal by human beings may be said to period from 1700 to the early eighteenth century have begun when hunters of the earliest Stone and also led to movement from the country into Age tossed their gnawnNot bones overfor their shouldistribution- towns. The likes of Charles Townsend, Thomas ders’, indeed to such an extent that caves became Coke, Jethro Tull, Robert Bakewell and others so reduced in size that they could no longer be introduced improvements in animal husbandry and occupied, and their occupants were certainly not arable farming. The Enclosure Acts allowed those ‘cave-proud’. Until the nineteenth century waste with the wealth to purchase public fields and push disposal and sewerage systems and sewage treat- out small-scale farmers, causing a migration of men ment in the cities of Britain were very ineffective looking for wage labour in cities. although through the centuries the great houses New patterns of crop rotation and livestock and monasteries may have had better organized utilisation paved the way for better crop yields, a (and healthier) systems for dealing with waste. Yet greater diversity of wheat and vegetables and the in many towns refuse was allowed to rot in the ability to support more livestock. These changes also streets, and there was no concern with contamina- impacted society so that workers’ diets improved a tion of water supplies. little and contributed to a slow decline in the rural Environmental health was concerned initially death rate. Those who remained as farm workers with those factors that were easily identifiable as had a low living standard in damp and crowded affecting human health, but as the interaction of housing. Working on the land throughout the year, the environment with human health became bet- whatever the weather, and poor living conditions ter understood the role of environmental health still contributed to a low life expectancy. expanded. In some cases this was also accidental as These social changes and growth of towns made environmental health included a cadre of people it increasingly difficult to provide a consistent and able to deal with issues (and legislation) that had satisfactory food supply for those living in the no obvious body to implement control measures. urban areas. The increased productivity of the rural 2 Context, philosophy and principles of EH economy did not lead to improved quality, indeed Machinery enabled production to be vastly the conditions were ripe for fraudulent substitu- increased with economies of scale to be grasped. tion, and for food to be adulterated. As factories increased in size and complexity, they also needed more workers, who had to be housed nearby because, in the absence of public transport, The industrial revolution they had to be able to walk to work. The need The industrial revolution did not follow the agri- to house workers close to the factories resulted cultural revolution, rather they overlapped con- in street after street of small, poorly constructed siderably; for example, Abram Darby first smelted houses. There was little provision for drainage or local iron ore with coke made from Coalbrookdale refuse disposal; water supplies were inadequate and coal in 1709, and in the coming decades Shropshire usually grossly polluted.
Recommended publications
  • Vol 37 Issue 1.Qxp
    EH Forrest 27 Mathurin P, Abdelnour M, Ramond M-J et al. Early change in critical appraisal and meta-analysis of the literature. Crit Care Med bilirubin levels is an important prognostic factor in severe 1995; 23:1430-–9. alcoholic hepatitis treated with prednisolone. Hepatol 2003; 32 Bollaert P-E, Charpentier C, Levy B, Debouvrie M, Audiebert G, 38:1363–9 Larcan, A. Reversal of late septic shock with supraphysiologic 28 Morris JM, Forrest EH. Bilirubin response to corticosteroids in doses of hydrocortisone. Crit Care Med 1998; 26:645–50. alcoholic hepatitis. Eur J Gastroenterol Hepatol 2005; 17:759–62. 33 Staubach K-H, Schroeder J, Stuber F,Gehrke K,Traumann E, Zabel 29 Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O. P. Effect of pentoxifylline in severe sepsis: results of a randomised Pentoxifylline improves short term survival in severe alcoholic double-blind, placebo-controlled study. Arch Surg 1998; hepatitis: a double blind placebo controlled trial. Gastroenterol 133:94–100. 2000; 119:1637–48. 34 Bacher A, Mayer N, Klimscha W, Oismuller C, Steltzer H, 30 Lefering R, Neugebauer EAM. Steroid controversy in sepsis and Hammerle A. Effects of pentoxifylline on haemodynamics and septic shock: a meta-analysis. Crit Care Med 1995; 23:1294–303. oxygenation in septic and non-septic patients. Crit Care Med 31 Cronin L, Cook DJ, Carlet J et al. Corticosteroid for sepsis: a 1997; 25:795–800. GENERAL MEDICINE BOOKS YOU SHOULD READ of the spread of cholera across Europe and its eventual spread into The Medical Detective by Sandra England in the early nineteenth Hempel.
    [Show full text]
  • Now on Cholerad--The Special Lecture in the Second British ,Epidemiology
    ~~,,~lnalof Epidemiology Vol. 8. No. 4 Oct --- $now on cholerad--The Special Lecture in the second British ,Epidemiology and ...Public Health Course at Kansai .Systems Laboratory dn 24 AIJ~S~I968 - .- -- .-- -- - " -- Shinichi Tan'ihara ', Seiji Morioka 2, Kazunori Kodama 3, Tsutomu Hashimoto 2, Hiroshi Yanagawa I, and Walter W Holland TheSecond British Epidemiology and Public Health Course was held from 19 to 25 August 1996 in Osaka as a satellite meeting for the 14th lnternational Scientific Meeting of the lnternational Epidemiological Association. Thirty-three researchers from 10 countries participated in the course. Professor Walter W Holland gave a special lecture about Snow on cholera during the course, and the lecture revealed that Henry Whitehead who was a junior priest at that time contributed to Snow's work to prevent the cholera outbreak in Golden Square in 1854. What John Snow did in his life are reviewed in detail in this paper J Epiderniol, 1998 ; 8 : 185-1 94. -3 John Snow, cholera, Henry Whitehead, British Course After the success of the First British Epidemiology and as my first lecture to my students. I think almost all the Public Health Course in 1994 I). the \econd course was Japanese professors of epidemiology or publlc health would planned. The organising committee for the course (see Table Like to speak about John Snow in their lectures. I regret that in 1) was able to prepare it from 19 August to 25 August 1996 in the first course, I missed his lecture. But today, I can listeihto Osaka, just bel'ore the 14th International Scientific Meeting for the lecw from fust to last.
    [Show full text]
  • The Ghost Map: the Story of London’S Most Terrifying Epidemic and How It Changed Science, Cities, and the Modern World by Steven Johnson
    Welcome to our April book, Historians! We will meet on Tuesday, April 3 at 6:30 to discuss The Ghost Map: The Story of London’s Most Terrifying Epidemic and How It Changed Science, Cities, and the Modern World by Steven Johnson. This is the story of the cholera outbreak in Victorian London in 1854. The book centers on Dr. John Snow who created a map of the cholera cases and the Reverend Henry Whitehead who knew the community through his church work and who was able to use this “social intelligence” to figure out the source of the outbreak, the now infamous water pump on Broad Street. In The Ghost Map, we meet these men and the victims and medical workers, both named and unnamed, who worked to stop a disease that no one understood or understood how it spread. Fighting disease in a densely populated urban environment was a new development in medicine. With two and one-half million inhabitants, no city in history had been as large as London is in 1854. When a disease like cholera hits, the results are devastating. As Johnson explains, cholera acts swiftly upon the body. People can die in as fast as twelve hours as cholera causes you to lose the water in your body. Sadly, because the water keeping your brain hydrated is the last water to disappear, victims are consciously dying, fully aware of their circumstances. The medical community believes that cholera is spread by bad air, what is called the miasma theory. Snow and Whitehead provide the evidence that cholera is spread by bad water, but the medical community is slow to accept the evidence, even when shutting down the Broad Street water pump ends the epidemic.
    [Show full text]
  • Note to Users
    - NOTE TO USERS The original manuscript received by UMI contains broken, slanted print, and margins exceed guidelines. All efforts were made to acquire the highest quality manuscript from the author or school. Microfilmed as received. This reproduction is the best copy available UMI MELTING SNOW: A RE-EXAMINATION OF DR JOHN SNOW, HIS DOT-MAP, AND THE 1854 BROAD STREET CHOLERA OUTBREAK Kari S. McLeod, B. A. (Honors) 1995 A thesis submitted to the Faculty of Graduate Studies in partid fuifil Iment of the requirement for the degree of Master of Arts Department of Geography Carleton University Ottawa, Ontario May 1,1998 O 1998, Kari S. McLeod National Librar y Bibliothèque nationale 1+m OfCrnada du Canada Acquisitions and Acquisitions et Bibliographie Services services bibliographiques The author has granted a non- L'auteur a accordé une licence non exclusive licence allowing the exclusive permettant à la National Library of Canach to Bibliothèque nationale du Canada de reproduce, loan, distnibute or sel1 reproduire, prêter, distn'buer ou copies of this thesis in microform, vendre des copies de cette thèse sous paper or electronic formats. la forme de microfiche/nlm, de reproduction sur papier ou sur format électronique. The author retams ownersbip of the L'auteur conserve la propriété du copyright in this thesis. Neither the droit d'auteur qui protège cette thèse. thesis nor substantial extracts fiom it Ni la thèse ni des extraits substantiels may be printed or otherwise de celle-ci ne doivent être imprimés reproduced without the author's ou autrement reproduits sans son permission. autorisation. ABSTRACT The mythical story of John Snow and the Broad Street outbreak is common in medical geography, epidemiology, and the history of medicine.
    [Show full text]
  • Cholera and the Pump on Broad Street
    CChhoolleerraa aanndd tthhee PPuummpp oonn BBrrooaadd SSttrreeeett:: THE LIFE AND LEGACY OF JOHN SNOW Laura Ball Senior Division Paper AFTER ALL, IT REALLY IS ALL OF HUMANITY THAT IS UNDER THREAT DURING A PANDEMIC. -- Dr. Margaret Chan, Director General of the World Health Organization There is still a pump in the Golden Square neighborhood on what was once called Broad Street. It does not work, for it is merely a replica of the original, and like the original its handle is missing. It serves as a curiously simple monument to the events that took place over one hundred years ago, when the real pump supplied water to the Broad Street residents. In 1854, hundreds of these hapless locals dropped dead within days of each other as Soho experienced one of the most brutal outbreaks of cholera that London has ever seen.1 Not even the most eminent physicians could say what caused the disease, or why it came and went as it did. John Snow’s solution to the cholera crisis broke the medical conventions of his era, slowed the progress of a virulent intercontinental disease, and forever changed the way society confronts public health problems. CHOLERA, THE BLUE DEATH Cholera plagued civilization for many generations before John Snow’s breakthrough. Medical researchers confirm that cholera was present in India in the seventeenth and eighteenth centuries, though records of diseases with cholera-like symptoms extend back as far as the fifth century B.C. The first intercontinental surge, referred to as the First Pandemic, occurred from 1 John Snow, “On the Mode of Communication of Cholera," 2nd ed., Snow on Cholera (New York: Hafner Publishing, 1965): 38.
    [Show full text]
  • Historiographical Unpacking—31 August 1854 Thursday, 31 August
    Historiographical Unpacking—31 August 1854 the participants, need to be unpacked if we are to be just in our assessments of actions taken dur- ing the point-source outbreak centered in Broad Street. Readers of the daily newspapers and major medical journals would have found many more theories than those I selected. It was a hot and contentious topic. Since the General Register Office regularly surveyed and assessed this litera- ture, I decided to narrow the field to the GRO’s report on the 1848-49 English cholera epidemic, Thursday, 31 August 1854 prepared under the direction of William Farr, the A normal day during a cholera epidemic in metro- examiner and compiler of abstracts and head of politan London. Figures from the seventh week of the statistical department. the epidemic, ending the previous Saturday, were Farr (1852) highlighted eight “theories available: 847 fatalities from Asiatic cholera in a and analogies,” from which I chose three fre- population greater than two and a quarter mil- quently cited by subsequent commentators who lion. Worrisome, but not as severe as the number eventually sought to explain the 1854 outbreak carried off by cholera during the seventh week of in St. James, Westminster parish (v). Farr’s the 1849 epidemic. In fact, there were hopeful multicausal zymotic theory and John Snow’s signs in the current epidemic’s weekly progress: alimentary-contagion theory are presented in one just 5 dead during the first week, followed by 26, extended scenario. The third theory, atmospheric 133, 399, 644, 729, and 847 in subsequent weeks infection, involved assumptions and reasoning (MTG 1854, 249).
    [Show full text]
  • Cholera and Clean Water Timeline Bob Phillips 1 Leeuwenhoek
    Cholera and Clean Water Timeline Bob Phillips Date Events Comment Citations from Miasma theory Going all the way back to the 1st century AD, the potential effects of miasma from fetid ancient swamplands was a key influence when siting a city. The Roman architectural writer Vitruvius times wrote of ―the morning breezes blowing towards town at sunrise mingled with the mist and the Wikipedia on Miasma poisonous breath of creatures of the marshes‖ Theory Miasma theory – that disease was carried through the air, in foul smells and such-like, persisted right into the Victorian age, with authorities like Dr. William Farr supporting the theory until the Hempel, p 35ff events of our tale induced him to change his mind. 1674 Magnified view of Antonie Philips van Leeuwenhoek (1632 – 1723) is best known for his work on the improvement Wikipedia on micro-organisms in of the microscope and for his contributions towards the establishment of microbiology . Using his Leeuwenhoek water handcrafted microscopes, he was the first to observe and describe single celled organisms, which he originally referred to as animalcules, and which we now refer to as micro-organisms. van Leeuwenhoek is often referred to as ―the Father of Microbiology‖ and he is considered to be the first microbiologist. He represents the beginning of our story of cholera, even though it was two centuries before ―animalcules‖ such as the ones he observed were identified as the agents that carried diseases like cholera. van Leeuwenhoek was a cloth mercnt in Delft, in the Netherlands. He first developed lenses to enable him to look more closely at the quality of cloth.He was a self-taught scientist, and He was the first to record microscopic observations of muscle fibers, bacteria spermatazoa and blood flow in capillaries (small blood vessels).
    [Show full text]
  • Analysis of Control Measures Used During Cholera Outbreaks Among Internally Displaced Persons Nicole Devine Carneal-Frazer Walden University
    Walden University ScholarWorks Walden Dissertations and Doctoral Studies Walden Dissertations and Doctoral Studies Collection 2019 Analysis of Control Measures Used During Cholera Outbreaks Among Internally Displaced Persons Nicole Devine Carneal-Frazer Walden University Follow this and additional works at: https://scholarworks.waldenu.edu/dissertations Part of the Epidemiology Commons This Dissertation is brought to you for free and open access by the Walden Dissertations and Doctoral Studies Collection at ScholarWorks. It has been accepted for inclusion in Walden Dissertations and Doctoral Studies by an authorized administrator of ScholarWorks. For more information, please contact [email protected]. Walden University College of Health Sciences This is to certify that the doctoral dissertation by Nicole Carneal-Frazer has been found to be complete and satisfactory in all respects, and that any and all revisions required by the review committee have been made. Review Committee Dr. Donald Goodwin, Committee Chairperson, Public Health Faculty Dr. Adebowale Awosika-Olumo, Committee Member, Public Health Faculty Dr. Jagdish Khubchandani, University Reviewer, Public Health Faculty Chief Academic Officer Eric Riedel, Ph.D. Walden University 2018 Abstract Analysis of Control Measures Used During Cholera Outbreaks Among Internally Displaced Persons by Nicole Carneal-Frazer MS, Walden University, 2014 BS, Lynchburg College, 2008 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Public Health Walden University February 2019 Abstract Cholera remains a major public health problem affecting high-risk populations such as camps of internally displaced persons. During a cholera outbreak, it is essential to reduce transmission and minimize new infections. The Miasma theory, host-agent-environment model and Ecosocial theory were utilized for this study.
    [Show full text]
  • Vibrio Cholerae and Studies on the Role of Serotype in Epidemic Spread of Cholera
    DEVELOPMENT OF NOVEL VACCINE STRAINS OF VIBRIO CHOLERAE AND STUDIES ON THE ROLE OF SEROTYPE IN EPIDEMIC SPREAD OF CHOLERA Stefan Karlsson Department of Microbiology & Immunology Institute of Biomedicine Sahlgrenska Academy at University of Gothenburg Cover illustration: Stefan Karlsson Development of novel vaccine strains of Vibrio cholerae and studies on the role of serotype in epidemic spread of cholera © Stefan Karlsson 2014 [email protected] ISBN 978–91–628–9122–0 Epub: ISBN 978–91–628–9152–7 http://hdl.handle.net/2077/35959 Printed by Ale Tryckteam AB Bohus, Sweden 2014 You and I may not live to see the day, and my name may be forgotten when it comes; but the time will arrive when great outbreaks of cholera will be things of the past; and it is the knowledge of the way in which the disease is propagated which will cause them to disappear. John Snow 1855 ABSTRACT. Cholera, caused by bacterium Vibrio cholerae O1, is a severe diarrheal disease with an estimated 3-5 million cases and more than 140 000 deaths every year particularly affecting children under 5 years of age. It can be found all over the world and often causes cholera in places where access to clean water or proper sanitary facilities are limited or compromised. Typically cholera follows in the wake of natural disasters or man-made catastrophes but it is also endemic in many countries including India and Bangladesh. Today there are two licensed vaccines available on the market in more than 60 countries. Despite the fact that these vaccines are effective they are both expensive and complicated to manufacture and there is scope and motivation for creating a new cheaper and more effective vaccine against cholera.
    [Show full text]
  • Sustainable Control of Water-Related Infectious Diseases: a Review And
    Review Sustainable Control of Water-Related Infectious Diseases: A Review and Proposal for Interdisciplinary Health-Based Systems Research Stuart Batterman,1 Joseph Eisenberg,2 Rebecca Hardin,3 Margaret E. Kruk,4 Maria Carmen Lemos,3 Anna M. Michalak,5 Bhramar Mukherjee,6 Elisha Renne,7 Howard Stein,8 Cristy Watkins,9 and Mark L. Wilson2 1Department of Environmental Health Sciences, 2Department of Epidemiology, 3School of Natural Resources and the Environment, 4Department of Health Management and Policy, 5Department of Civil and Environmental Engineering, 6Department of Biostatistics, 7Department of Environmental Engineering, 8Center for African American Studies, and 9School of Natural Resources and Environment, University of Michigan, Ann Arbor, Michigan, USA generally directed against proximal causes of OB JECTIVE : Even when initially successful, many interventions aimed at reducing the toll of water- infection transmission, paying less (and often related infectious disease have not been sustainable over longer periods of time. Here we review his- insufficient) attention to the more distal causal torical practices in water-related infectious disease research and propose an interdisciplinary public factors. This proximal focus comes from an health‒oriented systems approach to research and intervention design. individual-based approach to etiology and DATA sources: On the basis of the literature and the authors’ experiences, we summarize contribu- epidemiology that emphasizes the immedi- tions from key disciplines and identify common problems and trends. Practices in developing coun- ate and short-term risk factors. We suggest tries, where the disease burden is the most severe, are emphasized. that incorporating more distal processes into DATA extraction: We define waterborne and water-associated vectorborne diseases and identify analyses and designs of interventions will result disciplinary themes and conceptual needs by drawing from ecologic, anthropologic, engineering, in more sustainable interventions.
    [Show full text]
  • A Clinical Approach to Alcoholic Hepatitis
    J R Coll Physicians Edinb 2007; 37:3–8 PAPER © 2007 Royal College of Physicians of Edinburgh A clinical approach to alcoholic hepatitis EH Forrest Consultant Hepatologist, Department of Gastroenterology, Glasgow Royal Infirmary, Glasgow, Scotland ABSTRACTThere has been a dramatic increase in alcoholic liver disease in Scotland Published online March 2007 over recent years. Alcoholic hepatitis is perhaps the most florid manifestation of this, however considerable controversy exists regarding its diagnosis and Correspondence to E Forrest, management. This review indicates that it is possible to confidently make a Department of Gastroenterology, diagnosis of alcoholic hepatitis on clinical grounds using a minimum threshold of Wards 8/9, Glasgow Royal Infirmary, serum bilirubin as a diagnostic criterion. All patients with alcoholic hepatitis need Castle Street, Glasgow G4 0SF GENERAL MEDICINE nutritional assessment and support. The severity of alcoholic hepatitis can be tel. +44 (0)141 211 0734 ascertained using the Discriminant Function, however the Glasgow Alcoholic Hepatitis Score appears to be more specific and accurate predictor of outcome. fax. +44 (0)141 552 6126 Patients with severe disease should be considered for specific treatment. The evidence is in favour of corticosteroids which have the added benefit of allowing e-mail Ewan.Forrest@northglasgow. responsiveness to the treatment to be assessed after one week. Pentoxifylline scot.nhs.uk may be a useful alternative to corticosteroids. The patients with alcoholic hepatitis and concomitant
    [Show full text]
  • SHEN-DISSERTATION-2019.Pdf (12.95Mb)
    ENGINEERING SHANGHAI: WATER, SEWAGE, AND THE MAKING OF HYDRAULIC MODERNITY A Dissertation Presented to The Academic Faculty by Xincheng Shen In Partial Fulfillment Of the Requirements for the Degree PhD in the SCHOOL OF HISTORY AND SOCIOLOGY Georgia Institute of Technology MAY 2019 COPYRIGHT © 2019 BY XINCHENG SHEN ENGINEERING SHANGHAI: WATER, SEWAGE, AND THE MAKING OF HYDRAULIC MODERNITY Approved by: Dr. Hanchao Lu, Advisor Dr. Joe Brown School of History and Sociology School of Civil and Environmental Georgia Institute of Technology Engineering Georgia Institute of Technology Dr. John Krige Dr. John Tone School of History and Sociology School of History and Sociology Georgia Institute of Technology Georgia Institute of Technology Dr. Laura Bier School of History and Sociology Georgia Institute of Technology Date Approved: [March 11, 2019] In Memory of My Grandparents ACKNOWLEDGEMENTS The origin of this research is a myth. As far as I recall, I came up with this idea of studying city water infrastructures as a midway to combine my archaeology background and the new pursuit of STS and urban history. But my father insists that he is the one who crafted the theme in one of our many conversations. Either way, I owe a great deal to my parents, whose integrity, compassion, patriotism, and thirst for knowledge never cease to amaze me. Living up to their expectation is not easy. With this dissertation completed I hope I am half way there. Six years ago, I decided to come to Georgia Tech for my PhD study. It turned out to be one of the best decisions I have ever made.
    [Show full text]